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https://www.readbyqxmd.com/read/28507223/should-neurotechnological-treatments-offered-to-offenders-always-be-in-their-best-interests
#1
Thomas Søbirk Petersen
The paper critically discusses the moral view that neurotechnological behavioural treatment for criminal offenders should only be offered if it is in their best interests. First, I show that it is difficult to apply and assess the notion of the offender's best interests unless one has a clear idea of what 'best interests' means. Second, I argue that if one accepts that harmful punishment of offenders has a place in the criminal justice system, it seems inconsistent not to accept the practice of offering offenders treatment even when the state will harm them in applying the treatment...
May 15, 2017: Journal of Medical Ethics
https://www.readbyqxmd.com/read/28503833/moral-enhancement-meets-normative-and-empirical-reality-assessing-the-practical-feasibility-of-moral-enhancement-neurotechnologies
#2
Veljko Dubljević, Eric Racine
Moral enhancement refers to the possibility of making individuals and societies better from a moral standpoint. A fierce debate has emerged about the ethical aspects of moral enhancement, notably because steering moral enhancement in a particular direction involves choosing amongst a wide array of competing options, and these options entail deciding which moral theory or attributes of the moral agent would benefit from enhancement. Furthermore, the ability and effectiveness of different neurotechnologies to enhance morality have not been carefully examined...
June 2017: Bioethics
https://www.readbyqxmd.com/read/28488252/multiscale-modeling-in-the-clinic-diseases-of-the-brain-and-nervous-system
#3
REVIEW
William W Lytton, Jeff Arle, Georgiy Bobashev, Songbai Ji, Tara L Klassen, Vasilis Z Marmarelis, James Schwaber, Mohamed A Sherif, Terence D Sanger
Computational neuroscience is a field that traces its origins to the efforts of Hodgkin and Huxley, who pioneered quantitative analysis of electrical activity in the nervous system. While also continuing as an independent field, computational neuroscience has combined with computational systems biology, and neural multiscale modeling arose as one offshoot. This consolidation has added electrical, graphical, dynamical system, learning theory, artificial intelligence and neural network viewpoints with the microscale of cellular biology (neuronal and glial), mesoscales of vascular, immunological and neuronal networks, on up to macroscales of cognition and behavior...
May 9, 2017: Brain Informatics
https://www.readbyqxmd.com/read/28444626/towards-new-human-rights-in-the-age-of-neuroscience-and-neurotechnology
#4
Marcello Ienca, Roberto Andorno
Rapid advancements in human neuroscience and neurotechnology open unprecedented possibilities for accessing, collecting, sharing and manipulating information from the human brain. Such applications raise important challenges to human rights principles that need to be addressed to prevent unintended consequences. This paper assesses the implications of emerging neurotechnology applications in the context of the human rights framework and suggests that existing human rights may not be sufficient to respond to these emerging issues...
December 2017: Life Sciences, Society and Policy
https://www.readbyqxmd.com/read/28443008/against-strong-ethical-parity-situated-cognition-theses-and-transcranial-brain-stimulation
#5
Jan-Hendrik Heinrichs
According to a prominent suggestion in the ethics of transcranial neurostimulation the effects of such devices can be treated as ethically on par with established, pre-neurotechnological alterations of the mind. This parity allegedly is supported by situated cognition theories showing how external devices can be part of a cognitive system. This article will evaluate this suggestion. It will reject the claim, that situated cognition theories support ethical parity. It will however point out another reason, why external carriers or modifications of the mental might come to be considered ethically on par with internal carriers...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28420362/clinical-hemispheric-and-autonomic-changes-associated-with-use-of-closed-loop-allostatic-neurotechnology-by-a-case-series-of-individuals-with-self-reported-symptoms-of-post-traumatic-stress
#6
Charles H Tegeler, Jared F Cook, Catherine L Tegeler, Joshua R Hirsch, Hossam A Shaltout, Sean L Simpson, Brian C Fidali, Lee Gerdes, Sung W Lee
BACKGROUND: The objective of this pilot study was to explore the use of a closed-loop, allostatic, acoustic stimulation neurotechnology for individuals with self-reported symptoms of post-traumatic stress, as a potential means to impact symptomatology, temporal lobe high frequency asymmetry, heart rate variability (HRV), and baroreflex sensitivity (BRS). METHODS: From a cohort of individuals participating in a naturalistic study to evaluate use of allostatic neurotechnology for diverse clinical conditions, a subset was identified who reported high scores on the Posttraumatic Stress Disorder Checklist (PCL)...
April 19, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28381924/we-must-invest-in-applied-knowledge-of-computational-neurosciences-and-neuroinformatics-as-an-important-future-in-malaysia-the-malaysian-brain-mapping-project
#7
EDITORIAL
Putra Sumari, Zamzuri Idris, Jafri Malin Abdullah
The Academy of Sciences Malaysia and the Malaysian Industry-Government group for High Technology has been working hard to project the future of big data and neurotechnology usage up to the year 2050. On the 19 September 2016, the International Brain Initiative was announced by US Under Secretary of State Thomas Shannon at a meeting that accompanied the United Nations' General Assembly in New York City. This initiative was seen as an important effort but deemed costly for developing countries. At a concurrent meeting hosted by the US National Science Foundation at Rockefeller University, numerous countries discussed this massive project, which would require genuine collaboration between investigators in the realms of neuroethics...
March 2017: Malaysian Journal of Medical Sciences: MJMS
https://www.readbyqxmd.com/read/28335018/dissecting-gamma-frequency-activity-during-human-memory-processing
#8
Michal T Kucewicz, Brent M Berry, Vaclav Kremen, Benjamin H Brinkmann, Michael R Sperling, Barbara C Jobst, Robert E Gross, Bradley Lega, Sameer A Sheth, Joel M Stein, Sandthitsu R Das, Richard Gorniak, S Matthew Stead, Daniel S Rizzuto, Michael J Kahana, Gregory A Worrell
Gamma frequency activity (30-150 Hz) is induced in cognitive tasks and is thought to reflect underlying neural processes. Gamma frequency activity can be recorded directly from the human brain using intracranial electrodes implanted in patients undergoing treatment for drug-resistant epilepsy. Previous studies have independently explored narrowband oscillations in the local field potential and broadband power increases. It is not clear, however, which processes contribute to human brain gamma frequency activity, or their dynamics and roles during memory processing...
March 13, 2017: Brain: a Journal of Neurology
https://www.readbyqxmd.com/read/28269579/development-of-semi-chronic-microdrive-system-for-large-scale-circuit-mapping-in-macaque-mesolimbic-and-basal-ganglia-systems
#9
Shaoyu Qiao, Kevin A Brown, Amy L Orsborn, Breonna Ferrentino, Bijan Pesaran
The development of novel neurotechnologies for treating refractory neuropsychiatry disorders depends on understanding and manipulating the dynamics of neural circuits across large-scale brain networks. The mesolimbic pathway plays an essential role in reward processing and mood regulation and disorders of this pathway underlie many neuropsychiatric disorders. Here, we present the design of a customized semi-chronic microdrive array that precisely targets the anatomical structures of non-human primate (NHP) mesolimbic and basal ganglia systems...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28269266/neuronix-enables-continuous-simultaneous-neural-recording-and-electrical-microstimulation
#10
Zhi Yang, Jian Xu, Anh Tuan Nguyen, Tong Wu, Wenfeng Zhao, Wing-Kin Tam
This paper reports a novel neurotechnology (Neuronix) and its validation through experiments. It is a miniature system-on-chip (SoC) that allows recording with simultaneous electrical microstimulation. This function has not been demonstrated before and enables precise, closed-loop neuromodulation. Neuronix represents recent advancement in brain technology and applies to both animal research and clinical applications.
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227834/development-of-semi-chronic-microdrive-system-for-large-scale-circuit-mapping-in-macaque-mesolimbic-and-basal-ganglia-systems
#11
Shaoyu Qiao, Kevin A Brown, Amy L Orsborn, Breonna Ferrentino, Bijan Pesaran, Shaoyu Qiao, Kevin A Brown, Amy L Orsborn, Breonna Ferrentino, Bijan Pesaran, Shaoyu Qiao, Amy L Orsborn, Breonna Ferrentino, Kevin A Brown, Bijan Pesaran
The development of novel neurotechnologies for treating refractory neuropsychiatry disorders depends on understanding and manipulating the dynamics of neural circuits across large-scale brain networks. The mesolimbic pathway plays an essential role in reward processing and mood regulation and disorders of this pathway underlie many neuropsychiatric disorders. Here, we present the design of a customized semi-chronic microdrive array that precisely targets the anatomical structures of non-human primate (NHP) mesolimbic and basal ganglia systems...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227500/neuronix-enables-continuous-simultaneous-neural-recording-and-electrical-microstimulation
#12
Zhi Yang, Jian Xu, Anh Tuan Nguyen, Tong Wu, Wenfeng Zhao, Wing-Kin Tam, Zhi Yang, Jian Xu, Anh Tuan Nguyen, Tong Wu, Wenfeng Zhao, Wing-Kin Tam, Zhi Yang, Anh Tuan Nguyen, Jian Xu, Tong Wu, Wenfeng Zhao, Wing-Kin Tam
This paper reports a novel neurotechnology (Neuronix) and its validation through experiments. It is a miniature system-on-chip (SoC) that allows recording with simultaneous electrical microstimulation. This function has not been demonstrated before and enables precise, closed-loop neuromodulation. Neuronix represents recent advancement in brain technology and applies to both animal research and clinical applications.
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28198703/implantable-optoelectronic-probes-for-in-vivo-optogenetics
#13
Ege Iseri, Duygu Kuzum
More than a decade has passed since optics and genetics came together and lead to the emerging technologies of optogenetics. The advent of light-sensitive opsins made it possible to optically trigger the neurons into activation or inhibition by using visible light. The importance of spatiotemporally isolating a segment of a neural network and controlling nervous signaling in a precise manner has driven neuroscience researchers and engineers to invest great efforts in designing high precision in vivo implantable devices...
February 15, 2017: Journal of Neural Engineering
https://www.readbyqxmd.com/read/28129140/committing-to-memory-memory-prosthetics-show-promise-in-helping-those-with-neurodegenerative-disorders
#14
Michele Solis
Cell phone chimes, sticky notes, even the proverbial string around a finger-these timehonored external cues help guard against our inevitable memory lapses. But some internal help to the brain itself may be on the way in the form of what's being called memory prosthetics. Once considered to be on the fringes of neuroscience, the idea of adding hardware to the brain to help with memory has gathered steam. In 2014, the U.S. Defense Advanced Research Projects Agency (DARPA) made a US$30 million investment in memory prosthetic research as part of the Obama administration's Brain Research through Advancing Innovative Neurotechnologies initiative...
January 2017: IEEE Pulse
https://www.readbyqxmd.com/read/28113241/m3ba-a-mobile-modular-multimodal-biosignal-acquisition-architecture-for-miniaturized-eeg-nirs-based-hybrid-bci-and-monitoring
#15
Alexander von Luhmann, Heidrun Wabnitz, Tilmann Sander, Klaus-Robert Muller
OBJECTIVE: For the further development of the fields of telemedicine, neurotechnology and Brain-Computer Interfaces (BCI), advances in hybrid multimodal signal acquisition and processing technology are invaluable. Currently, there are no commonly available hybrid devices combining bio-electrical and bio-optical neurophysiological measurements (here Electroencephalography (EEG) and functional Near Infrared Spectroscopy (fNIRS)). Our objective was the design of such an instrument, and that in a miniaturized, customizable and wireless form...
September 9, 2016: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/28030932/usage-of-perioperative-anxiety-neuromarker-for-improving-the-quality-of-life-of-a-patient-operated-on-for-critical-stenosis-of-the-internal-carotid-artery
#16
Mariusz Trystuła, Paweł Półrola, Juri Kropotov
OBJECTIVE: The aim of the study was to find a neuromarker of perioperative anxiety in a patient with critical carotid stenosis through the use of neuromarkers in Quantitative EEG (QEEG) and Event Related Potentials (ERPs). The indirect purpose of the research was evaluation of improvement in the patient's quality of life. CASE STUDY: A 45-year-old woman was admitted to the Department of Vascular Surgery and Endovascular Interventions at the John Paul II Hospital in Krakow, with the diagnosis of critical internal carotid stenosis (over 80%), confirmed by Doppler Ultrasound and Angio-CT examinations...
December 23, 2016: Annals of Agricultural and Environmental Medicine: AAEM
https://www.readbyqxmd.com/read/28009249/manipulating-memories-the-ethics-of-yesterday-s-science-fiction-and-today-s-reality
#17
Julie M Robillard, Judy Illes
The paper addresses recent advances in memory manipulation from the perspective of the four key pillars of neuroethics: the self, social policy, neurotechnology, and education and outreach. We provide examples for each pillar, assess their neuroethical implications, and conclude with a call for an ethics framework that is specifically tailored for the ethical challenges of memory manipulation.
December 1, 2016: AMA Journal of Ethics
https://www.readbyqxmd.com/read/27979758/a-testbed-for-optimizing-electrodes-embedded-in-the-skull-or-in-artificial-skull-replacement-pieces-used-after-injury
#18
JingLe Jiang, Amar R Marathe, Jennifer C Keene, Dawn M Taylor
BACKGROUND: Custom-fitted skull replacement pieces are often used after a head injury or surgery to replace damaged bone. Chronic brain recordings are beneficial after injury/surgery for monitoring brain health and seizure development. Embedding electrodes directly in these artificial skull replacement pieces would be a novel, low-risk way to perform chronic brain monitoring in these patients. Similarly, embedding electrodes directly in healthy skull would be a viable minimally-invasive option for many other neuroscience and neurotechnology applications requiring chronic brain recordings...
February 1, 2017: Journal of Neuroscience Methods
https://www.readbyqxmd.com/read/27930909/fda-regulation-of-neurological-and-physical-medicine-devices-access-to-safe-and-effective-neurotechnologies-for-all-americans
#19
Leigh Anderson, Patrick Antkowiak, Aden Asefa, Amber Ballard, Tushar Bansal, Ayo Bello, Bernard Berne, Kristen Bowsher, Bennett Blumenkopf, Ian Broverman, Mohamad Bydon, Kuo Chao, Peter Como, Karlene Cork, Ann Costello, Kathryn De Laurentis, Angela DeMarco, Heather Dean, John Doucet, Bradley Dworak, Lisa Epperson, Eric Franca, Naz Ghassemian, Chandramallika Ghosh, Anupama Govindarajan, Jay Gupta, Stacie Gutowski, Robert Herrmann, Michael Hoffmann, William Heetderks, Steven Hsu, Daryl Kaufman, Erin Keegan, Gregg Kittlesen, Kevin Khuu, Hyung Lee, Larry Lo, Ian Marcus, Timothy Marjenin, Binoy Mathews, Sanjay Misra, Vivek Pinto, Vesper Ramos, Samuel Raben, Avena Russell, Devjani Saha, Joonil Seog, Christian Shenouda, Myra Smith, Xiaorui Tang, Kelliann Wachrathit, Jaime Waterhouse, Dhanya Williams, Xiaolin Zheng, Carlos Peña
The United States Food and Drug Administration (FDA) ensures that patients in the U.S. have access to safe and effective medical devices. The Division of Neurological and Physical Medicine Devices reviews medical technologies that interface with the nervous system. This article addresses how to navigate the FDA's regulatory landscape to successfully bring medical devices to patients.
December 7, 2016: Neuron
https://www.readbyqxmd.com/read/27917107/the-berlin-brain-computer-interface-progress-beyond-communication-and-control
#20
REVIEW
Benjamin Blankertz, Laura Acqualagna, Sven Dähne, Stefan Haufe, Matthias Schultze-Kraft, Irene Sturm, Marija Ušćumlic, Markus A Wenzel, Gabriel Curio, Klaus-Robert Müller
The combined effect of fundamental results about neurocognitive processes and advancements in decoding mental states from ongoing brain signals has brought forth a whole range of potential neurotechnological applications. In this article, we review our developments in this area and put them into perspective. These examples cover a wide range of maturity levels with respect to their applicability. While we assume we are still a long way away from integrating Brain-Computer Interface (BCI) technology in general interaction with computers, or from implementing neurotechnological measures in safety-critical workplaces, results have already now been obtained involving a BCI as research tool...
2016: Frontiers in Neuroscience
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