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Percutaneous coronary intervention

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https://www.readbyqxmd.com/read/29691963/length-of-stay-following-percutaneous-coronary-intervention-an-expert-consensus-document-update-from-the-society-for-cardiovascular-angiography-and-interventions
#1
Arnold H Seto, Adhir Shroff, Mazen Abu-Fadel, James C Blankenship, Konstantinos Dean Boudoulas, Joaquin E Cigarroa, Gregory J Dehmer, Dmitriy N Feldman, Daniel M Kolansky, Kusum Lata, Rajesh V Swaminathan, Sunil V Rao
Since the publication of the 2009 SCAI Expert Consensus Document on Length of Stay Following percutaneous coronary intervention (PCI), advances in vascular access techniques, stent technology, and antiplatelet pharmacology have facilitated changes in discharge patterns following PCI. Additional clinical studies have demonstrated the safety of early and same day discharge in selected patients with uncomplicated PCI, while reimbursement policies have discouraged unnecessary hospitalization. This consensus update: (1) clarifies clinical and reimbursement definitions of discharge strategies, (2) reviews the technological advances and literature supporting reduced hospitalization duration and risk assessment, and (3) describes changes to the consensus recommendations on length of stay following PCI (Supporting Information Table S1)...
April 24, 2018: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29691803/association-of-beta-blockers-with-survival-on-patients-presenting-with-acs-treated-with-pci-a-propensity-score-analysis-from-the-bleemacs-registry
#2
Fabrizio D'Ascenzo, Dario Celentani, Alessandro Brustio, Alberto Grosso, Sergio Raposeiras-Roubín, Emad Abu-Assi, Jose Paulo Simao Henriques, Jorge Saucedo, José Ramón González-Juanatey, Stephen B Wilton, Wouter J Kikkert, Iván Nuñez-Gil, Albert Ariza-Sole, Xiantao Song, Dimitrios Alexopoulos, Christoph Liebetrau, Tetsuma Kawaji, Zenon Huczek, Shao-Ping Nie, Toshiharu Fujii, Luis Correia, Masa-Aki Kawashiri, José María García-Acuña, Danielle Southern, Emilio Alfonso, Belén Terol, Alberto Garay, Dongfeng Zhang, Yalei Chen, Ioanna Xanthopoulou, Neriman Osman, Helge Möllmann, Hiroki Shiomi, Michal Kowara, Krzysztof Filipiak, Xiao Wang, Yan Yan, Jing-Yao Fan, Yuji Ikari, Takuya Nakahayshi, Kenji Sakata, Masakazu Yamagishi, Oliver Kalpak, Sasko Kedev, Claudio Moretti, Maurizio D'Amico, Fiorenzo Gaita
PURPOSE: The aim was to evaluate prognostic value of beta-blocker (BB) administration in acute coronary syndromes (ACS) patients in the percutaneous coronary intervention (PCI) era. METHODS AND RESULTS: The BleeMACS project is a multicenter, observational, retrospective registry enrolling patients with ACS worldwide in 15 hospitals. Patients discharged with BB therapy were compared to those discharged without a BB before and after propensity score with matching...
April 24, 2018: American Journal of Cardiovascular Drugs: Drugs, Devices, and Other Interventions
https://www.readbyqxmd.com/read/29691767/prognostic-impact-of-final-kissing-balloon-technique-after-crossover-stenting-for-the-left-main-coronary-artery-from-the-aoi-lmca-registry
#3
Koji Nishida, Mamoru Toyofuku, Takeshi Morimoto, Masanobu Ohya, Yasushi Fuku, Hirooki Higami, Kyohei Yamaji, Hiromi Muranishi, Yuhei Yamaji, Daisuke Furukawa, Tomohisa Tada, Euihong Ko, Kazushige Kadota, Kenji Ando, Hiroki Sakamoto, Takashi Tamura, Kazuya Kawai, Takeshi Kimura
It is still uncertain whether the final kissing balloon technique (FKBT) is mandatory after crossover stenting for the left main coronary artery (LMCA). Assessing Optimal Percutaneous Coronary Intervention for LMCA (AOI-LMCA) registry, a 6-center retrospective registry, enrolled 1809 consecutive patients for LMCA stenting in Japan. In the present analysis, 5-year clinical outcomes were compared between non-FKBT (n = 160) and FKBT (n = 578) groups in patients treated with crossover stenting with drug-eluting stents from the LMCA to the left anterior descending artery...
April 24, 2018: Cardiovascular Intervention and Therapeutics
https://www.readbyqxmd.com/read/29691643/the-relationship-between-timing-of-prasugrel-pretreatment-and-in-stent-thrombus-immediately-after-percutaneous-coronary-intervention-for-acute-coronary-syndrome-an-optical-coherence-tomography-study
#4
Yosuke Katayama, Takashi Kubo, Yasushi Ino, Takeyoshi Kameyama, Yoshiki Matsuo, Hironori Kitabata, Kosei Terada, Hiroki Emori, Hiroshi Aoki, Akira Taruya, Kunihiro Shimamura, Shingo Ota, Atsushi Tanaka, Takeshi Hozumi, Takashi Akasaka
The optimal timing of pretreatment with prasugrel in percutaneous coronary intervention (PCI) for acute coronary syndrome (ACS) is unclear. We used optical coherence tomography (OCT) to compare in-stent thrombus volume immediately after PCI between the administration of low-dose prasugrel (20 mg loading dose) at the time of diagnosis of ACS (early prasugrel: n = 34) and the administration of low-dose prasugrel immediately after diagnostic angiography prior to PCI for ACS (late prasugrel: n = 56). The durations between the administration of prasugrel and OCT in the early prasugrel group and late prasugrel group were 5...
April 24, 2018: Heart and Vessels
https://www.readbyqxmd.com/read/29691185/common-themes-in-patients-requiring-urgent-cardiothoracic-surgery-after-percutaneous-coronary-interventions-case-series-and-review-of-the-literature
#5
REVIEW
Saad Ezad, Trent D Williams, Jeremy Condon, Andrew J Boyle, Nicholas J Collins
Urgent cardiothoracic surgical intervention for the management of complications of percutaneous coronary intervention is uncommon in the stent era. Nonetheless, given increasing procedural complexity, in part reflecting an aging population, an ongoing hazard for urgent surgery remains. We sought to review the incidence and outcome of urgent cardiothoracic surgery in patients undergoing PCI in a contemporary cohort at a tertiary referral centre. The incidence of cardiothoracic intervention for PCI related complications was low at 0...
March 21, 2018: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/29691182/staff-radiation-dose-during-percutaneous-coronary-procedures-role-of-adjunctive-protective-drapes
#6
Alessandro Sciahbasi, Alessandro Sarandrea, Stefano Rigattieri, Roberto Patrizi, Maria Cera, Cristian Di Russo, Francesco Perone, Vanessa Porretta, Silvio Fedele, Silvio Romano, Maria Penco, Giuseppe Ferraiuolo
BACKGROUND: The use of adjunctive protective drapes placed on the patient protects the operating physician from scatter radiation during percutaneous coronary procedures (PCP). No data are available on the effect of these drapes for staff members' radio-protection. PURPOSE: To evaluate staff radiation exposure during PCP and the effect of adjunctive protective drapes on dose reduction. METHODS: The RADIANT study (NCT01974453) is a prospective, observational study evaluating operator radiation exposure during PCP using electronic dosimeter...
April 6, 2018: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/29691071/incidence-determinants-and-clinical-impact-of-definite-stent-thrombosis-on-mortality-in-women-from-the-win-des-collaborative-patient-level-pooled-analysis
#7
Laura S Kerkmeijer, Bimmer E Claessen, Usman Baber, Samantha Sartori, Jaya Chandrasekhar, Giulio G Stefanini, Gregg W Stone, P Gabriel Steg, Alaide Chieffo, Giora Weisz, Stephan Windecker, Ghada W Mikhail, Adnan Kastrati, Marie-Claude Morice, George D Dangas, Robbert J de Winter, Roxana Mehran
BACKGROUND: Predictors and clinical outcomes of stent thrombosis (ST) in women have not been well investigated. Present study aimed to identify predictors of definite ST and its impact on mortality in women undergoing percutaneous coronary intervention (PCI). METHODS: Patient-level data of women enrolled in 26 randomized trials of DES was pooled. The study population was stratified based on the presence or absence of definite ST. Cox proportional hazards models were used to determine the predictors of definite ST...
April 12, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29689569/microrna-223-regulates-cardiac-fibrosis-after-myocardial-infarction-by-targeting-rasa1
#8
Xiaoxiao Liu, Yifeng Xu, Yunfei Deng, Hongli Li
BACKGROUND/AIMS: Percutaneous coronary intervention reduces acute myocardial infarction (MI)-induced mortality to a great extent, but effective treatments for MI-induced cardiac fibrosis and heart failure are still lacking. MicroRNAs (miRNAs) play a variety of roles in cells and have thus been investigated extensively. MicroRNA-223 (miR-223) expression has been reported to be altered in post-MI heart failure in humans; however, the roles of miR-223 in MI remain unknown. Our study aimed to elucidate the roles of miR-223 in cardiac fibrosis...
April 19, 2018: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/29688904/chronic-total-occlusion-intervention-of-the-non-infarct-related-artery-in-acute-myocardial-infarction-patients-the-korean-multicenter-chronic-total-occlusion-registry
#9
Ji Young Park, Byoung Geol Choi, Seung-Woon Rha, Tae Soo Kang, Cheol Ung Choi, Cheol Woong Yu, Hyeon-Cheol Gwon, In-Ho Chae, Hyo-Soo Kim, Hun Sik Park, Seung-Hwan Lee, Moo-Hyun Kim, Seung-Ho Hur, Yangsoo Jang
BACKGROUND: The Korean chronic total occlusion (CTO) registry was collected prospectively from 26 cardiovascular centers since May 2007. The aim of this study is to investigate the impact of a successful staged percutaneous coronary intervention (PCI) of CTO lesions in acute myocardial infarction (AMI) patients on clinical outcomes. PATIENTS AND METHODS: Among 2813 patients who underwent a staged PCI because of CTO lesions, 422 (15%) patients underwent primary PCI because of AMI...
April 23, 2018: Coronary Artery Disease
https://www.readbyqxmd.com/read/29688419/clinical-impact-of-direct-stenting-and-interaction-with-thrombus-aspiration-in-patients-with-st-segment-elevation-myocardial-infarction-undergoing-percutaneous-coronary-intervention-thrombectomy-trialists-collaboration
#10
Karim D Mahmoud, Sanjit S Jolly, Stefan James, Vladimír Džavík, John A Cairns, Goran K Olivecrona, Henrik Renlund, Peggy Gao, Bo Lagerqvist, Ashraf Alazzoni, Sasko Kedev, Goran Stankovic, Brandi Meeks, Ole Frøbert, Felix Zijlstra
Aims: Preliminary studies suggest that direct stenting (DS) during percutaneous coronary intervention (PCI) may reduce microvascular obstruction and improve clinical outcome. Thrombus aspiration may facilitate DS. We assessed the impact of DS on clinical outcome and myocardial reperfusion and its interaction with thrombus aspiration among ST-segment elevation myocardial infarction (STEMI) patients undergoing PCI. Methods and results: Patient-level data from the three largest randomized trials on routine manual thrombus aspiration vs...
April 21, 2018: European Heart Journal
https://www.readbyqxmd.com/read/29688287/implications-of-coronary-artery-bypass-grafting-and-percutaneous-coronary-intervention-on-disease-progression-and-the-resulting-changes-to-the-physiology-and-pathology-of-the-native-coronary-arteries
#11
Jacqueline H Fortier, Giovanni Ferrari, David Glineur, Mario Gaudino, Richard E Shaw, Marc Ruel, Juan B Grau
Myocardial revascularization can be achieved through 2 different methods: coronary artery bypass grafting (CABG) and percutaneous coronary intervention (PCI). Clinical trials comparing PCI and CABG generally use the composite end points of death, stroke, myocardial infarction and target vessel revascularization to determine superiority. Other effects of these interventions, including the preservation of normal coronary physiology, the response of the coronary tree to stressors and the response of the vessel wall to the revascularization intervention, are not routinely considered, but these may have significant implications for patients in the medium and long term...
April 23, 2018: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29688176/impact-of-bleeding-assessment-and-adjudication-methodology-on-event-rates-and-clinical-trial-outcomes-insights-from-the-horizons-ami-trial
#12
Ioanna Kosmidou, Gary S Mintz, Tannas Jatene, Monica Embacher, Björn Redfors, S Chiu Wong, Ovidiu Dressler, Roxana Mehran, Ori Ben-Yehuda, Paul L Jenkins, Gregg W Stone
AIMS: Bleeding is a major safety outcome in cardiovascular trials. The present study assessed the impact of the adjudication process of bleeding events on 3-year outcomes in the Harmonizing Outcomes with Revascularization and Stents in Acute Myocardial Infarction (HORIZONS-AMI) trial. METHODS AND RESULTS: HORIZONS-AMI enrolled 3,602 patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention. An independent CEC reviewed 445 potential bleeding events identified from 3 sources: 339 site-reported (SR), 35 CEC-identified, and 71 database (DB)-triggered events based on programmatic identification of a decline in hemoglobin of ≥3 g/dL or in hematocrit by ≥9%; of those, 383/445 (86...
April 24, 2018: EuroIntervention
https://www.readbyqxmd.com/read/29687877/the-mechanism-of-exogenous-adiponectin-in-the-prevention-of-no-reflow-phenomenon-in-type-2-diabetic-patients-with-acute-myocardial-infarction-during-pci-treatment
#13
C-J Zhang, Y-Z Deng, Y-H Lei, J-B Zhao, W Wei, Y-H Li
OBJECTIVE: To investigate the mechanism of exogenous adiponectin in the prevention of no-reflow phenomenon in type 2 diabetic (T2DM) patients with acute myocardial infarction (AMI) during percutaneous coronary intervention (PCI) treatment. PATIENTS AND METHODS: 66 patients were randomly divided into control group and observation group, 33 cases in each group. According to the percutaneous coronary intervention (PCI) emergency treatment principle, patients from the control group were treated with an intracoronary injection of adenosine combined with a micro-pump intravenous infusion of tirofiban...
April 2018: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29687703/surgical-myocardial-revascularization-in-patients-with-reduced-systolic-left-ventricular-function
#14
Piergiorgio Bruno, Mauro Iafrancesco, Massimo Massetti
Surgical myocardial revascularization in patients with reduced left ventricular function has been a matter of debate for decades. Recently published 10-years extension follow-up of the STICH trial have conclusively demonstrated benefit of surgical myocardial revascularization in patients with significant coronary artery disease and low left ventricular ejection fraction. However, selection of patients for surgery remains challenging as well as decision to perform percutaneous rather than surgical revascularization in this class of patients...
April 20, 2018: Minerva Cardioangiologica
https://www.readbyqxmd.com/read/29687700/impella-pumps-overview-and-access-site-management
#15
Francesco Burzotta, Giulo Russo, Leonardo Previ, Piergiorgio Bruno, Cristina Aurigemma, Carlo Trani
The Impella left ventricular support system consists of two main components: a family of different ventricular support catheters with a microaxial pump to be placed across the aortic valve and a single external controller (AIC) which is connected to activate and control the pump function. Four Impella left ventricular support catheters are available: Impella 2.5, Impella CP, Impella 5.0 and Impella LD. Impella 2.5 and Impella CP are designed for percutaneous peripheral insertion, have respectively a 12F and 14F maximal diameter at the pump level and are capable of providing up to 2...
April 20, 2018: Minerva Cardioangiologica
https://www.readbyqxmd.com/read/29687699/merging-the-properties-of-a-sirolimus-coated-balloon-with-those-of-a-bioresorbable-polymer-sirolimus-eluting-stent-to-address-the-diabetes-issue-results-from-the-en-abl-multicenter-registry
#16
Luca Testa, Sameer Dani, Devang Desai, Rashmit Pandya, Pritesh Parekh, Nirav Bhalani, Arvind Sharma, Chirag Seth, Manish Doshi, Prakash Sojitra, Poonam Chodvadiya, Gopee Dutta, Francesco Bedogni
BACKGROUND: Patients with diabetes mellitus (DM) have poorer outcomes after percutaneous coronary intervention than patients without diabetes. The Abluminus DES+TM drug-eluting stent (DES) features a novel technology of fusion coating of PLLA bioresorbable polymer on both the abluminal surface of the stent and exposed parts of the balloon. AIM: To evaluate the efficacy/safety profile of the Abluminus DES+ in an all-comers population with minimal exclusion criteria and with a specific focus on diabetic patients...
April 20, 2018: Minerva Cardioangiologica
https://www.readbyqxmd.com/read/29687412/optimal-pharmacological-therapy-in-st-elevation-myocardial-infarction-a-review-a-review-of-antithrombotic-therapies-in-stemi
#17
REVIEW
R S Hermanides, S Kilic, A W J van 't Hof
Antithrombotic therapy is an essential component in the optimisation of clinical outcomes in patients with ST-elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention. There are currently several intravenous anticoagulant drugs available for primary percutaneous coronary intervention. Dual antiplatelet therapy comprising aspirin and P2Y12 inhibitor represents the cornerstone treatment for STEMI. However, these effective treatment strategies may be associated with bleeding complications...
April 23, 2018: Netherlands Heart Journal
https://www.readbyqxmd.com/read/29686623/ticagrelor-improves-endothelial-function-by-decreasing-circulating-epidermal-growth-factor-egf
#18
Francesco Vieceli Dalla Sega, Francesca Fortini, Giorgio Aquila, Rita Pavasini, Simone Biscaglia, Davide Bernucci, Annamaria Del Franco, Elisabetta Tonet, Paola Rizzo, Roberto Ferrari, Gianluca Campo
Ticagrelor is one of the most powerful P2Y12 inhibitor. We have recently reported that, in patients with concomitant Stable Coronary Artery Disease (SCAD) and Chronic Obstructive Pulmonary Disease (COPD) undergoing percutaneous coronary intervention (PCI), treatment with ticagrelor, as compared to clopidogrel, is associated with an improvement of the endothelial function (Clinical Trial NCT02519608). In the present study, we showed that, in the same population, after 1 month treatment with ticagrelor, but not with clopidogrel, there is a decrease of the circulating levels of epidermal growth factor (EGF) and that these changes in circulating levels of EGF correlate with on-treatment platelet reactivity...
2018: Frontiers in Physiology
https://www.readbyqxmd.com/read/29686544/thrombolytic-use-in-the-region-around-amarillo-texas-in-patients-with-st-elevation-myocardial-infarction
#19
Kelly S McMaster, Totini Chatterjee, Drew McBrayer, David Brabham
Appropriate administration of thrombolytic therapy is particularly important for ST elevation myocardial infarction (STEMI) patients who are unable to access primary percutaneous coronary intervention (PCI) in a timely manner. We evaluated the current state of thrombolytic therapy in the Panhandle region of West Texas where access to primary PCI is poor. The medical records of 79 patients transferred from 20 outlying facilities to the two hospitals in Amarillo, Texas, for STEMI in 2016 were retrospectively evaluated for time of onset of chest pain, initial electrocardiogram findings, medication reconciliation, and any contraindications to thrombolytic therapy...
January 2018: Proceedings of the Baylor University Medical Center
https://www.readbyqxmd.com/read/29686543/overall-survival-and-brain-death-frequency-following-out-of-hospital-cardiac-arrest
#20
Charles E Howard, John S Garrett, Robert C Stoler, Jeffrey M Schussler
Out-of-hospital cardiac arrest (OHCA) is a major cause of mortality that is responsible for over 300,000 deaths in the United States each year. Underlying cardiac etiologies remain the most common culprit. Despite medical advances in the treatment of coronary artery disease, the mortality following OHCA remains dismal. Additionally, of those who survive the initial event, many are left with debilitating and irreversible anoxic brain injuries. Therefore, improving survival as well as neurologic outcome is of primary importance in this group...
January 2018: Proceedings of the Baylor University Medical Center
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