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https://www.readbyqxmd.com/read/28098530/fatal-infection-with-murray-valley-encephalitis-virus-imported-from-australia-to-canada-2011
#1
Daniel J Niven, Kevin Afra, Mircea Iftinca, Raymond Tellier, Kevin Fonseca, Andreas Kramer, David Safronetz, Kimberly Holloway, Michael Drebot, Andrew S Johnson
Murray Valley encephalitis virus (MVEV), a flavivirus belonging to the Japanese encephalitis serogroup, can cause severe clinical manifestations in humans. We report a fatal case of MVEV infection in a young woman who returned from Australia to Canada. The differential diagnosis for travel-associated encephalitis should include MVEV, particularly during outbreak years.
February 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/28098398/depression-and-discrimination-in-the-lives-of-women-transgender-and-gender-liminal-people-in-ontario-canada
#2
Charmaine C Williams, Deone Curling, Leah S Steele, Margaret F Gibson, Andrea Daley, Datejie Cheko Green, Lori E Ross
This article uses an intersectionality lens to explore how experiences of race, gender, sexuality, class and their intersections are associated with depression and unmet need for mental healthcare in a population of 704 women and transgender/gender liminal people from Ontario, Canada. A survey collecting demographic information, information about mental health and use of mental healthcare services, and data for the Everyday Discrimination Scale and the PHQ-9 Questionnaire for Depression was completed by 704 people via Internet or pen-and-paper between June 2011 and June 2012...
January 18, 2017: Health & Social Care in the Community
https://www.readbyqxmd.com/read/28097711/pharmacists-perceptions-of-pay-for-performance-versus-fee-for-service-remuneration-for-the-management-of-hypertension-through-pharmacist-prescribing
#3
Meagen M Rosenthal, Nimisha Desai, Sherilyn K D Houle
OBJECTIVES: As pharmacists expand their roles as patient care providers, remuneration must be offered for patient care activities apart from dispensing. Most jurisdictions paying for such services utilize the fee-for-service (FFS) model, while little is known about the role of pay for performance (P4P) within the pharmacy profession. This study aimed to elicit the experience of pharmacists practicing under both models within the Alberta Clinical Trial in Optimizing Hypertension (RxACTION) study in Alberta, Canada...
January 18, 2017: International Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/28097356/effect-of-etelcalcetide-vs-cinacalcet-on-serum-parathyroid-hormone-in-patients-receiving-hemodialysis-with-secondary-hyperparathyroidism-a-randomized-clinical-trial
#4
Geoffrey A Block, David A Bushinsky, Sunfa Cheng, John Cunningham, Bastian Dehmel, Tilman B Drueke, Markus Ketteler, Reshma Kewalramani, Kevin J Martin, Sharon M Moe, Uptal D Patel, Justin Silver, Yan Sun, Hao Wang, Glenn M Chertow
Importance: Secondary hyperparathyroidism contributes to extraskeletal calcification and is associated with all-cause and cardiovascular mortality. Control is suboptimal in the majority of patients receiving hemodialysis. An intravenously (IV) administered calcimimetic could improve adherence and reduce adverse gastrointestinal effects. Objective: To evaluate the relative efficacy and safety of the IV calcimimetic etelcalcetide and the oral calcimimetic cinacalcet...
January 10, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/28097355/effect-of-etelcalcetide-vs-placebo-on-serum-parathyroid-hormone-in-patients-receiving-hemodialysis-with-secondary-hyperparathyroidism-two-randomized-clinical-trials
#5
Geoffrey A Block, David A Bushinsky, John Cunningham, Tilman B Drueke, Markus Ketteler, Reshma Kewalramani, Kevin J Martin, T Christian Mix, Sharon M Moe, Uptal D Patel, Justin Silver, David M Spiegel, Lulu Sterling, Liron Walsh, Glenn M Chertow
Importance: Secondary hyperparathyroidism contributes to extraskeletal complications in chronic kidney disease. Objective: To evaluate the effect of the intravenous calcimimetic etelcalcetide on serum parathyroid hormone (PTH) concentrations in patients receiving hemodialysis. Design, Setting, and Participants: Two parallel, phase 3, randomized, placebo-controlled treatment trials were conducted in 1023 patients receiving hemodialysis with moderate to severe secondary hyperparathyroidism...
January 10, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/28097314/complications-of-bilateral-neck-dissection-in-thyroid-cancer-from-a-single-high-volume-center
#6
Caitlin McMullen, Daniel Rocke, Jeremy Freeman
Importance: The morbidity of bilateral lateral neck dissection (BLND) for thyroid cancers has not been described in detail. This study delineates the specific complications arising from BLND for thyroid cancers at a single high-volume center. Objective: To determine the morbidity associated with BLNDs for differentiated thyroid cancers at our institution. Design, Setting, and Participants: This was a retrospective review of medical records performed to identify patients having undergone BLNDs for thyroid cancers by a single surgeon at an academic, tertiary medical center in Toronto, Ontario, Canada, from 1988 to 2015...
January 12, 2017: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28096934/first-line-treatment-options-in-metastatic-renal-cell-cancer
#7
REVIEW
Anil Kapoor
The introduction of targeted therapy a decade ago revolutionized the treatment of metastatic renal cell carcinoma (mRCC). The current standard of care focuses on the inhibition of angiogenesis through the targeting of the vascular endothelial growth factor receptor (VEGFR) and the mammalian target of rapamycin (mTOR). Currently recommended first-line treatments in Canada include sunitinib, pazopanib, and temsirolimus. With the heterogeneity of mRCC disease, the choice of treatment is driven largely by prognostic factors...
November 2016: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/28096756/116th-annual-meeting-medical-library-association-inc-toronto-on-canada-may-15-20-2015
#8
Nicole Mitchell
No abstract text is available yet for this article.
January 2017: Journal of the Medical Library Association: JMLA
https://www.readbyqxmd.com/read/28095762/a-moral-profession
#9
Roger Newham, Louise Terry, Siobhan Atherley, Sinead Hahessy, Yolanda Babenko-Mould, Marilyn Evans, Karen Ferguson, Graham Carr, S H Cedar
BACKGROUND: Lack of compassion is claimed to result in poor and sometimes harmful nursing care. Developing strategies to encourage compassionate caring behaviours are important because there is evidence to suggest a connection between having a moral orientation such as compassion and resulting caring behaviour in practice. OBJECTIVE: This study aimed to articulate a clearer understanding of compassionate caring via nurse educators' selection and use of published texts and film...
January 1, 2017: Nursing Ethics
https://www.readbyqxmd.com/read/28095709/worldwide-trends-of-urinary-stone-disease-treatment-over-the-last-two-decades-a-systematic-review
#10
Robert Geraghty, Patrick Jones, Bhaskar K Somani
INTRODUCTION: Numerous studies have reported on regional or national trends of stone disease treatment. However, no paper has yet examined the global trends of intervention for stone disease. METHODS AND MATERIALS: A systematic review of papers from 2004 to September 2016 for all English language articles reporting on trends of surgical treatment of stone disease was performed. Authors were contacted in the case of data not being clear. If the authors did not reply, data was estimated from graphs or tables...
January 17, 2017: Journal of Endourology
https://www.readbyqxmd.com/read/28095585/clinical-nursing-leadership-education-in-long-term-care-intervention-design-and-evaluation
#11
Valerie Fiset, Tracy Luciani, Alyssa Hurtubise, Theresa L Grant
The main objective of the current case study was to investigate the perceived leadership learning needs and feasibility of delivering leadership education to registered staff involved in direct care in long-term care (LTC) homes. The study was conducted in Ontario, Canada, and participants included RNs, registered practical nurses, and nursing administrators. Phase 1 bilingual web-based survey and bilingual focus group needs assessment data supported a preference for external training along with in-house mentoring to support sustainability...
January 17, 2017: Journal of Gerontological Nursing
https://www.readbyqxmd.com/read/28095539/a-proposed-method-for-upper-eyelid-and-infrabrow-tightening-using-a-transcutaneous-temperature-controlled-radiofrequency-device-with-opaque-plastic-eye-shields
#12
Douglas J Key, Lauren Boudreaux
BACKGROUND: Laxity of the eyelid and periorbital area, a common manifestation of aging, is usually addressed via blepharoplasty and/ or fat transfer. Given the trend toward safer, less invasive treatments preferred by those patients reticent to undergo more invasive procedures, viable alternatives have been sought. Transcutaneous temperature controlled radiofrequency (TTCRF) integrates non- invasive super cial RF treatment with automatic temperature feedback control of energy deposition, as a stimulator of overall collagen remodeling; however, the globe of the eye is particularly sensitive to RF energy...
November 1, 2016: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/28095034/self-reported-driving-under-the-influence-of-alcohol-and-cannabis-among-ontario-students-associations-with-graduated-licensing-risk-taking-and-substance-abuse
#13
Steven Cook, Danielle Shank, Tara Bruno, Nigel E Turner, Robert E Mann
OBJECTIVE: This paper describes the patterns of self-reported driving under the influence of alcohol (DUIA) and driving under the influence of cannabis (DUIC) among licenced Ontario students in 2009, and examines their associations with graduated licencing, risk taking, and substance use problems for understanding DUIA and DUIC behaviours. Ontario's graduated licencing system requires new drivers to hold a G1 license for a minimum of 8 months, and a G2 licence for a minimum of 12 months before a full and unrestricted G license can be obtained...
January 17, 2017: Traffic Injury Prevention
https://www.readbyqxmd.com/read/28094606/trichinella-surveillance-in-black-bears-ursus-americanus-from-the-dehcho-region-northwest-territories-canada-2002-2015
#14
Nicholas C Larter, Brett T Elkin, Lorry B Forbes, Brent Wagner, Danny G Allaire
We used muscle digestion to test black bears ( Ursus americanus ) from the southwestern Northwest Territories, Canada, for Trichinella. Results showed a prevalence of 4.1%. Some bears had infection intensities of more than one larva per gram (LPG) of muscle tissue; this level in meat is considered to pose a human consumption safety risk.
January 17, 2017: Journal of Wildlife Diseases
https://www.readbyqxmd.com/read/28094134/cervical-and-breast-cancer-screening-after-cares-a-community-program-for-immigrant-and-marginalized-women
#15
Sheila F Dunn, Aisha K Lofters, Ophira M Ginsburg, Christopher A Meaney, Farah Ahmad, M Catherine Moravac, Cam Tu Janet Nguyen, Angela M Arisz
INTRODUCTION: Marginalized populations such as immigrants and refugees are less likely to receive cancer screening. Cancer Awareness: Ready for Education and Screening (CARES), a multifaceted community-based program in Toronto, Canada, aimed to improve breast and cervical screening among marginalized women. This matched cohort study assessed the impact of CARES on cervical and mammography screening among under-screened/never screened (UNS) attendees. METHODS: Provincial administrative data collected from 1998 to 2014 and provided in 2015 were used to match CARES participants who were age eligible for screening to three controls matched for age, geography, and pre-education screening status...
January 13, 2017: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28093801/from-questions-to-answers-examining-the-role-of-pediatric-surveillance-units-in-eating-disorder-research
#16
Debra K Katzman, Sloane Madden, Dasha Nicholls, Karizma Mawjee, Mark L Norris
Pediatric Surveillance Units (PSUs) provide a unique model for the study of pediatric eating disorders (EDs). Australia, Britain, and Canada have surveillance programs that have generated valuable epidemiological and clinical data on early-onset eating disorders (EOED). The PSUs represent an important collaborative tool that has helped shape our understanding of EOEDs and offers potential to contribute to decisions regarding health resource allocation and public health policy. This paper reviews the role of PSUs as a unique model to study pediatric EDs and its success in translating the knowledge generated by these programs into improving the health of children and adolescents with EDs worldwide...
January 17, 2017: International Journal of Eating Disorders
https://www.readbyqxmd.com/read/28093680/the-international-diffuse-intrinsic-pontine-glioma-registry-an-infrastructure-to-accelerate-collaborative-research-for-an-orphan-disease
#17
Joshua Baugh, Ute Bartels, James Leach, Blaise Jones, Brooklyn Chaney, Katherine E Warren, Jenavieve Kirkendall, Renee Doughman, Cynthia Hawkins, Lili Miles, Christine Fuller, Tim Hassall, Eric Bouffet, Adam Lane, Darren Hargrave, Jacques Grill, Lindsey M Hoffman, Chris Jones, Alex Towbin, Sharon A Savage, Michelle Monje, Xiao-Nan Li, David S Ziegler, Sophie Veldhuijzen van Zanten, Christof M Kramm, Dannis G van Vuurden, Maryam Fouladi
Diffuse intrinsic pontine glioma (DIPG), a rare, often fatal childhood brain tumor, remains a major therapeutic challenge. In 2012, investigators, funded by the DIPG Collaborative (a philanthropic partnership among 29 private foundations), launched the International DIPG Registry (IDIPGR) to advance understanding of DIPG. Comprised of comprehensive deidentified but linked clinical, imaging, histopathological, and genomic repositories, the IDIPGR uses standardized case report forms for uniform data collection; serial imaging and histopathology are centrally reviewed by IDIPGR neuro-radiologists and neuro-pathologists, respectively...
January 16, 2017: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/28092966/avian-influenza-prevalence-among-hunter-harvested-birds-in-a-remote-canadian-first-nation-community
#18
Eric N Liberda, Richard Meldrum, Nadia A Charania, Robert Davey, Leonard Js Tsuji
INTRODUCTION: Avian influenza virus (AIV) prevalence has been associated with wild game and other bird species. The contamination of these birds may pose a greater risk to those who regularly hunt and consumed infected species. Due to resident concerns communicated by local Band Council, hunter-harvested birds from a remote First Nation community in subArctic Ontario, Canada were assessed for AIV. Hunters, and especially those who live a subsistence lifestyle, are at higher risk of AIV exposure due to their increased contact with wild birds, which represent an important part of their diet...
January 2017: Rural and Remote Health
https://www.readbyqxmd.com/read/28092768/mercury-levels-in-herring-gulls-and-fish-42-years-of-spatio-temporal-trends-in-the-great-lakes
#19
E Agnes Blukacz-Richards, Ariola Visha, Matthew L Graham, Daryl L McGoldrick, Shane R de Solla, David J Moore, George B Arhonditsis
Total mercury levels in aquatic birds and fish communities have been monitored across the Canadian Great Lakes by Environment and Climate Change Canada (ECCC) for the past 42 years (1974-2015). These data (22 sites) were used to examine spatio-temporal variability of mercury levels in herring gull (Larus argentatus) eggs, lake trout (Salvelinus namaycush), walleye (Sander vitreus), and rainbow smelt (Osmerus mordax). Trends were quantified with dynamic linear models, which provided time-variant rates of change of mercury concentrations...
December 30, 2016: Chemosphere
https://www.readbyqxmd.com/read/28091990/revaluation-of-stockpile-amount-of-pfos-containing-aqueous-film-forming-foam-in-japan-gaps-and-pitfalls-in-the-stockpile-survey
#20
Yasuyuki Zushi, Atsushi Yamamoto, Kiyotaka Tsunemi, Shigeki Masunaga
Stockpiles of perfluoro-octane sulfonic acid (PFOS) containing aqueous film-forming foam (AFFF) have the potential to be emitted by leaching, spills, and during use in fire response and other processes. Several studies have discussed the high levels of stockpiled PFOS-containing AFFF and the risk they pose to the environment; however, there are large gaps in the amounts in Japan compared with other countries. For example, 300 tons are stockpiled in Canada, 2200-2600 tons in Switzerland, 1400 tons in Norway, and 19,000 tons in Japan from their reports for publication...
January 13, 2017: Environmental Science and Pollution Research International
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