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Small intestinal bacterial overgrowth

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https://www.readbyqxmd.com/read/29773218/kleine-levin-syndrome-the-contribution-of-pet-scan-and-hydrogen-breath-test-for-small-intestinal-bacterial-overgrowth
#1
Andrea Melpignano, Giulia Milioli, Anna Bertelè, Anna Elisabetta Vaudano, Caterina Ghetti, Liborio Parrino, Livia Ruffini
No abstract text is available yet for this article.
June 2018: Sleep Medicine
https://www.readbyqxmd.com/read/29762383/starch-tolerance-and-the-short-bowel
#2
Jan de Laffolie, Hassan Y Naim, Silvia Rudloff, Klaus-Peter Zimmer
Short bowel syndrome with intestinal failure is a rare disease with a massive impairment in quality of life, requiring a multidisciplinary team approach to medical, surgical, and nutritional therapy. Current pharmacological and surgical therapeutic options are limited; an important cornerstone is enteral and parenteral nutrition. The changed physiology of carbohydrate digestion plays a major role in the adaptation process and can be a target for specific enteral nutrition interventions. An important prognostic factor is the preservation of at least portions of the colon in continuity with small bowel...
June 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29761252/testing-and-treating-small-intestinal-bacterial-overgrowth-reduces-symptoms-in-patients-with-inflammatory-bowel-disease
#3
Shirley Cohen-Mekelburg, Zaid Tafesh, Elliot Coburn, Russell Weg, Neena Malik, Colleen Webb, Hoda Hammad, Ellen Scherl, Brian P Bosworth
BACKGROUND: Common mechanisms against small intestinal bacterial overgrowth (SIBO), including an intact ileocecal valve, gastric acid secretion, intestinal motility, and an intact immune system, are compromised in inflammatory bowel disease (IBD), and therefore, a relatively high incidence of SIBO has been reported in this population. AIMS: We aimed to determine whether an improvement in IBD clinical activity scores is seen after testing and treating SIBO. METHODS: A retrospective cohort study of 147 patients with inflammatory bowel disease who were referred for SIBO breath testing from 1/2012 to 5/2016 was performed...
May 14, 2018: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/29761234/prevalence-and-predictors-of-small-intestinal-bacterial-overgrowth-in-irritable-bowel-syndrome-a-systematic-review-and-meta-analysis
#4
REVIEW
Binrui Chen, John Jae-Woo Kim, Yawen Zhang, Lijun Du, Ning Dai
BACKGROUND: The reported prevalence of small intestinal bacterial overgrowth (SIBO) among individuals with irritable bowel syndrome (IBS) is highly variable. The aim of the study is to estimate the prevalence and identify predictors of SIBO in IBS. METHODS: PubMed, Cochrane Library, and EMBASE through July 2017 were searched to identify studies evaluating the prevalence of SIBO in IBS. The pooled prevalence of SIBO among individuals with IBS and the pooled odds ratio (OR) of SIBO among those with IBS compared with healthy controls were calculated...
May 14, 2018: Journal of Gastroenterology
https://www.readbyqxmd.com/read/29752215/chronic-pancreatitis-and-small-intestinal-bacterial-overgrowth
#5
EDITORIAL
Matthew J DiMagno, Chris E Forsmark
No abstract text is available yet for this article.
May 3, 2018: Pancreatology: Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]
https://www.readbyqxmd.com/read/29729056/a-case-of-small-intestinal-bacterial-overgrowth-performed-capsule-and-double-balloon-endoscopy
#6
Ichiro Otani, Shiro Oka, Shinji Tanaka
A 67-year old woman who had received treatment with prednisolone for systemic scleroderma visited our hospital. She complained of mild abdominal pain, bloating, anorexia, watery stools (approximately three times a day). Abdominal computed tomography showed high contrast appearance and thickening of the entire small intestinal wall as well as accumulation of intestinal fluid with no mechanical obstruction (Figure 1). Capsule endoscopy (Figure 2a) and antegrade double-balloon endoscopy (Figure 2b) revealed retention of cloudy intestinal fluid throughout the entire small intestine with reddish and edematous mucosa...
May 5, 2018: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/29713027/evaluation-of-chronic-diarrhea-and-irritable-bowel-syndrome-with-diarrhea-in-adults-in-the-era-of-precision-medicine
#7
REVIEW
Lawrence R Schiller
Chronic diarrhea is a common clinical problem, affecting roughly 5% of the population in any given year. Evaluation and management of these patients can be difficult due to the extensive differential diagnosis of this symptom. Many patients with chronic diarrhea have structural problems, such as inflammatory bowel disease or celiac disease, that can be readily identified. Others do not, and often are given a diagnosis of irritable bowel syndrome with diarrhea (IBS-D). When based on generally accepted clinical criteria, a diagnosis of IBS-D identifies a group of patients who are unlikely to have disorders producing anatomical changes in the gut...
May 1, 2018: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/29691369/does-colectomy-predispose-to-small-intestinal-bacterial-sibo-and-fungal-overgrowth-sifo
#8
Satish S C Rao, George Tan, Hamza Abdulla, Siegfried Yu, Sebastian Larion, Pornchai Leelasinjaroen
OBJECTIVES: After subtotal colectomy, 40% of patients report chronic gastrointestinal symptoms and poor quality of life. Its etiology is unknown. We determined whether small intestinal bacterial overgrowth (SIBO) or small intestinal fungal overgrowth (SIFO) cause gastrointestinal symptoms after colectomy. METHODS: Consecutive patients with unexplained abdominal pain, gas, bloating and diarrhea (>1 year), and without colectomy (controls), and with colectomy were evaluated with symptom questionnaires, glucose breath test (GBT) and/or duodenal aspiration/culture...
April 25, 2018: Clinical and Translational Gastroenterology
https://www.readbyqxmd.com/read/29687525/does-a-glucose-based-hydrogen-and-methane-breath-test-detect-bacterial-overgrowth-in-the-jejunum
#9
O H Sundin, A Mendoza-Ladd, E Morales, B M Fagan, M Zeng, D Diaz-Arévalo, J Ordoñez, R W McCallum
BACKGROUND: Direct diagnosis of small intestinal bacterial overgrowth (SIBO) requires the collection and culture of fluid from the jejunal lumen, with a finding of over 105 viable bacteria per mL. More often, SIBO is diagnosed indirectly, using a non-invasive test of the exhaled hydrogen and methane generated by microbial fermentation when ingested glucose reaches the jejunum. Our objective was to determine how well this breath test detects chronic overgrowth of jejunal bacteria that is unrelated to gastrointestinal surgery...
April 23, 2018: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/29678362/bowel-symptoms-in-patients-that-receive-proton-pump-inhibitors-results-of-a-multicenter-survey-in-mexico
#10
M J Schmulson, A C Frati-Munari
INTRODUCTION: Proton pump inhibitors (PPIs) have been associated with small intestinal bacterial overgrowth (SIBO), which increases with prolonged PPI use, and SIBO has been associated with irritable bowel syndrome (IBS). OBJECTIVE: The aim of the present study was to study the prevalence of bowel symptoms in patients treated with PPIs in Mexico. METHODS: Gastroenterologists in 36 cities surveyed patients treated with PPIs, utilizing an ad hoc questionnaire to determine the presence of bowel symptoms and IBS...
April 17, 2018: Revista de Gastroenterología de México
https://www.readbyqxmd.com/read/29652914/intestinal-manipulation-affects-mucosal-antimicrobial-defense-in-a-mouse-model-of-postoperative-ileus
#11
Kathy Stein, Lena Hieggelke, Bianca Schneiker, Mariola Lysson, Burkhard Stoffels, Sabine Nuding, Jan Wehkamp, Judith Kikhney, Annette Moter, Joerg C Kalff, Sven Wehner
AIM: To explore the effects of abdominal surgery and interleukin-1 signaling on antimicrobial defense in a model of postoperative ileus. METHODS: C57BL/6 and Interleukin-1 receptor type I (IL-1R1) deficient mice underwent intestinal manipulation to induce POI. Expression of mucosal IL-1α, IL-1β and IL-1R1 and several antimicrobial peptides and enzymes were measured by quantitative PCR or ELISA, western blotting or immunohistochemistry. Bacterial overgrowth was determined by fluorescent in-situ hybridization and counting of jejunal luminal bacteria...
2018: PloS One
https://www.readbyqxmd.com/read/29623817/restless-legs-syndrome-in-patients-infected-with-helicobacter-pylori
#12
Farzaneh Rezvani, Mohammad Sayadnasiri, Omid Rezaei
Objective Although the etiology of restless legs syndrome (RLS) is yet to be discovered, some studies have mentioned the effect of infectious diseases in occurrence of RLS. This study aims to determine the association between common Helicobacter pylori (H. pylori) infection and occurrence of RLS. Methods In this descriptive analytical cross-sectional study, patients with RLS who were referred to the Internal Medicine Clinic of Fayazbakhsh Hospital in Tehran from September to December 2016 were evaluated. Patients with underlying diseases that would lead to secondary RLS were excluded from the study...
April 6, 2018: Neurological Research
https://www.readbyqxmd.com/read/29605778/cirrhosis-following-single-anastomosis-duodeno-ileal-switch-a-case-report
#13
Vincent Kirkpatrick, Rena C Moon, Andre F Teixeira, Muhammad A Jawad
INTRODUCTION: Single anastomosis duodeno-ileal switch (SADI-S) involves a single, loop duodeno-ileal anastomosis with omission of the traditional Roux-en-Y distal ileo-ileal anastomosis. Not much has been published on the complications of SADI-S. PRESENTATION OF CASE: The patient is a 40 year-old male who underwent robot-assisted SADI-S three years prior. At the time of surgery, his body mass index (BMI) was 69 kg/m2 . His BMI was 31 kg/m2 at the time of presentation...
March 17, 2018: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29596112/vagal-dysfunction-and-small-intestinal-bacterial-overgrowth-novel-pathways-to-chronic-inflammation-in-hiv
#14
Jessica Robinson-Papp, Alexandra Nmashie-Osei, Elizabeth Pedowitz, Emma K T Benn, Mary C George, Sandeep Sharma, Jacinta Murray, Josef Machac, Sherif Heiba, Saurabh Mehandru, Seunghee Kim-Schulze, Allison Navis, Isabel Elicer, Susan Morgello
OBJECTIVE: Chronic inflammation in HIV-infected individuals drives disease progression and the development of comorbidities, despite viral suppression with combined antiretroviral therapy. Here, we sought evidence that vagal dysfunction, which occurs commonly as part of HIV-associated autonomic neuropathy, could exacerbate inflammation through gastrointestinal dysmotility, small intestinal bacterial overgrowth (SIBO), and alterations in patterns of soluble immune mediators. DESIGN: This is a cross-sectional observational study...
March 28, 2018: AIDS
https://www.readbyqxmd.com/read/29589108/chronic-diarrhoea-following-surgery-for-colon-cancer-frequency-causes-and-treatment-options
#15
REVIEW
Jonathan Yde, Helene M Larsen, Søren Laurberg, Klaus Krogh, Hanne B Moeller
PURPOSE: The growing population of survivors after colon cancer warrants increased attention to the long-term outcome of surgical treatment. The change in bowel anatomy after resection disrupts normal gastrointestinal function and may cause symptoms. Thus, many patients surviving colon cancer have to cope with bowel dysfunction for the rest of their lives. We here aim to provide an overview of the literature on this topic. METHODS: We review long-term functional outcomes of surgical treatment for colon cancer, the underlying pathology, and treatment options...
March 27, 2018: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/29574688/dosing-of-ceftriaxone-and-metronidazole-for-children-with-severe-acute-malnutrition
#16
Joseph F Standing, Martin O Ongas, Caroline Ogwang, Nancy Kagwanja, Sheila Murunga, Shalton Mwaringa, Rehema Ali, Neema Mturi, Moline Timbwa, Christine Manyasi, Laura Mwalekwa, Victor L Bandika, Bernhards Ogutu, Joseph Waichungo, Karin Kipper, James A Berkley
Infants and young children with severe acute malnutrition (SAM) are treated with empiric broad-spectrum antimicrobials. Parenteral ceftriaxone is currently a second-line agent for invasive infection. Oral metronidazole principally targets small intestinal bacterial overgrowth. Children with SAM may have altered drug absorption, distribution, metabolism and elimination. Population pharmacokinetics of ceftriaxone and metronidazole were studied, with the aim of recommending optimal dosing. Eighty-one patients with SAM (aged 2-45 months) provided 234 post-dose pharmacokinetic samples for total ceftriaxone, metronidazole and hydroxymetronidazole...
March 25, 2018: Clinical Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/29508268/effect-of-a-preparation-of-four-probiotics-on-symptoms-of-patients-with-irritable-bowel-syndrome-association-with-intestinal-bacterial-overgrowth
#17
Konstantinos Leventogiannis, Paraskevas Gkolfakis, Georgios Spithakis, Aikaterini Tsatali, Aikaterini Pistiki, Athanasios Sioulas, Evangelos J Giamarellos-Bourboulis, Konstantinos Triantafyllou
The effect of probiotics on small intestinal bacterial overgrowth (SIBO) in irritable bowel syndrome (IBS) has never been studied so far. In this prospective trial, five patients with IBS and SIBO and 21 patients with IBS without SIBO were administered an oral capsule containing Saccharomyces boulardii, Bifidobacterium lactis, Lactobacillus acidophilus, and Lactobacillus plantarum (Lactolevure® ) every 12 h for 30 days. SIBO was defined by quantitative culture of the third part of the duodenum; IBS was defined by the Rome III criteria...
March 5, 2018: Probiotics and Antimicrobial Proteins
https://www.readbyqxmd.com/read/29502987/the-prevalence-of-small-intestinal-bacterial-overgrowth-in-non-surgical-patients-with-chronic-pancreatitis-and-pancreatic-exocrine-insufficiency-pei
#18
Hazel M Ní Chonchubhair, Yasir Bashir, Mark Dobson, Barbara M Ryan, Sinead N Duggan, Kevin C Conlon
BACKGROUND: Small intestinal bacterial overgrowth (SIBO) is a condition characterised by symptoms similar to pancreatic exocrine insufficiency (PEI) in chronic pancreatitis patients. SIBO is thought to complicate chronic pancreatitis in up to 92% of cases; however, studies are heterogeneous and protocols non-standardised. SIBO may be determined by measuring lung air-expiration of either hydrogen or methane which are by-products of small bowel bacterial fermentation of intraluminal substrates such as carbohydrates...
February 24, 2018: Pancreatology: Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]
https://www.readbyqxmd.com/read/29485256/the-association-between-cigarettes-smoke-small-intestine-bacterial-overgrowth-and-rosacea
#19
Francesco Drago, Giulia Ciccarese, Astrid Herzum, Francesca Drago, Alfredo Rebora, Aurora Parodi
No abstract text is available yet for this article.
February 26, 2018: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/29469038/bacterial-translocation-is-linked-to-increased-intestinal-ifn-%C3%AE-il-4-il-17-and-mucin-2-in-cholestatic-rats
#20
Natali Vega-Magaña, Vidal Delgado-Rizo, Leonel García-Benavides, Susana Del Toro-Arreola, Jorge Segura-Ortega, Adelaida Sara M Zepeda Morales, José Sergio Zepeda-Nuño, Marta Escarra-Senmarti, Jorge Gutiérrez-Franco, Jesse Haramati, Miriam R Bueno-Topete
Background and rationale for the study. Bacterial translocation is an important triggering factor of infection and mortality in cirrhosis. In a rat model using bile duct ligation (BDL), bacterial translocation appears within 24 h after ligation. The dynamic between TH1/TH2/TH17 cytokines and the integrity of the colonic mucosa in the context of cirrhosis is little known. This study aims to determine the link between bacterial translocation and intestinal inflammation in a cholestasis model. Additionally, alterations of the colonic mucus layer and the bacterial load were also addressed...
March 1, 2018: Annals of Hepatology
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