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https://www.readbyqxmd.com/read/28542895/aura-and-other-neurologic-dysfunction-in-or-with-migraine
#1
Narayan R Kissoon, Fred Michael Cutrer
PREMISE: Migraine can present with a wide range of neurological symptoms. PROBLEM: Based on currently available data, the symptoms of typical migraine aura are most likely related to cortical spreading depression (CSD), and evidence supports that CSD can lead to trigeminovascular activation resulting in the headache phase of migraine. POTENTIAL SOLUTION: An alternative diagnosis to migraine aura should be considered if migrainous headaches present with transient neurological symptoms that have features inconsistent with aura...
May 19, 2017: Headache
https://www.readbyqxmd.com/read/28542809/arterial-spin-labeled-mr-imaging-detecting-biphasic-neurovascular-changes-in-migraine-with-persistent-aura
#2
Robert Burns, Maxine De Malherbe, Marie-Laure Chadenat, Fernando Pico, Dan Buch
No abstract text is available yet for this article.
May 19, 2017: Headache
https://www.readbyqxmd.com/read/28541766/the-clinical-utility-of-vestibular-autorotation-test-in-patients-with-vestibular-migraine
#3
Yogun Thungavelu, Wei Wang, Peng Lin, Taisheng Chen, Kaixu Xu
OBJECTIVE: To investigate the characteristics and clinical utility of vestibular autorotation test (VAT) in patients with vestibular migraine. METHODS: This study included two groups, an experimental group (441 patients) and a control group (65 healthy subjects). Both groups undertook VAT; the parameters evaluated were horizontal gain/phase, vertical gain/phase and asymmetry. The differences in VAT results between the two groups were investigated. RESULTS: There were no statistical differences between the VAT data of the control group when compared to the reference value from the manufacturer (p > ...
May 25, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28541256/modulation-of-brainstem-activity-and-connectivity-by-respiratory-gated-auricular-vagal-afferent-nerve-stimulation-in-migraine-patients
#4
Ronald G Garcia, Richard L Lin, Jeungchan Lee, Jieun Kim, Riccardo Barbieri, Roberta Sclocco, Ajay D Wasan, Robert R Edwards, Bruce R Rosen, Nouchine Hadjikhani, Vitaly Napadow
Migraine pathophysiology includes altered brainstem excitability, and recent neuromodulatory approaches aimed at controlling migraine episodes have targeted key brainstem relay and modulatory nuclei. In this study, we evaluated the impact of respiratory-gated auricular vagal afferent nerve stimulation (RAVANS), a novel neuromodulatory intervention based on an existing transcutaneous vagus nerve stimulation approach, in the modulation of brainstem activity and connectivity in migraine patients. We applied 3T-functional magnetic resonance imaging with improved in-plane spatial resolution (2...
April 25, 2017: Pain
https://www.readbyqxmd.com/read/28540738/somatosensory-gating-is-altered-and-associated-with-migraine-chronification-a-magnetoencephalographic-study
#5
Fu-Jung Hsiao, Shuu-Jiun Wang, Yung-Yang Lin, Jong-Ling Fuh, Yu-Chieh Ko, Pei-Ning Wang, Wei-Ta Chen
Background Brain excitability is changed in migraine but not fully characterized yet. This study explored if somatosensory gating is altered in migraine and linked to migraine chronification. Methods Paired electrical stimuli were delivered to the left index fingers of 21 patients with migraine without aura (MO), 22 patients with chronic migraine (CM), and 36 controls. The first and second responses to the paired stimuli were obtained from the contralateral primary (cSI), contralateral secondary (cSII) and ipsilateral secondary (iSII) somatosensory cortices to compute the gating ratios (second vs...
January 1, 2017: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/28538577/in-depth-review-of-symptoms-triggers-and-treatment-of-occipital-migraine-headaches-site-iv
#6
Mona Ascha, David E Kurlander, Abdus Sattar, James Gatherwright, Bahman Guyuron
BACKGROUND: This study reports the surgical technique and efficacy of deactivation of occipital-triggered migraine headaches. In addition, it reports the effect of surgical deactivation of occipital-triggered migraine headaches on migraine triggers and associated symptoms other than pain. METHODS: One hundred ninety-five patients undergoing surgery for occipital-triggered migraine headaches performed by a single surgeon, and followed for at least 1 year, were analyzed...
June 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28538472/efficacy-of-intratympanic-gentamicin-in-m%C3%A3-ni%C3%A3-re-s-disease-with-and-without-migraine
#7
Yuan F Liu, Elizabeth Renk, Steven D Rauch, Helen X Xu
OBJECTIVE: To compare the efficacy of intratympanic gentamicin injection (ITG) on vertigo control, drop attacks, and functional level in Ménière's disease patients with and without a history of migraine. PATIENTS: Ménière's disease patients (patients with migraine and age- and sex-matched control patients without migraine) treated from 2002 to 2012 who failed medical management and received ITG, with a minimum 2-year follow up. INTERVENTION: ITG...
May 22, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28537581/the-effects-of-a-multispecies-probiotic-on-migraine-and-markers-of-intestinal-permeability-results-of-a-randomized-placebo-controlled-study
#8
N M de Roos, S van Hemert, J M P Rovers, M G Smits, B J M Witteman
BACKGROUND/OBJECTIVES: Migraine, associated with several gastrointestinal disorders, may result from increased intestinal permeability, allowing endotoxins to enter the bloodstream. We tested whether probiotics could reduce migraine through an effect on intestinal permeability and inflammation. SUBJECTS/METHODS: In total, 63 patients were randomly allocated to the probiotic (n=31) or the placebo group (n=32). Participants ingested a multispecies probiotic (5x10(9) colony-forming units) or placebo daily for 12 weeks...
May 24, 2017: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28536973/the-effect-of-maternal-migraine-headache-on-their-children-s-quality-of-life
#9
Belma Doğan Güngen, Yesim Güzey Aras, Sıdıka Sinem Gül, Türkan Acar, Ayşe Burcu Ayaz, Aybala Neslihan Alagöz, Bilgehan Atılgan Acar
Migraine is an episodic disease characterized by a throbbing and generally unilateral headache, often accompanied by nausea, vomiting and light and sound sensitivity. Migraine is known to affect one's quality of life; not only the person with migraine but also his/her family and social environment are affected by this condition. Our study aimed to evaluate the effects of maternal migraine on children's quality of life. The patient group comprised 70 mothers with migraine diagnoses and their 111 healthy children, while 50 healthy mothers and their 86 children were included in this study as the control group...
May 23, 2017: Acta Neurologica Belgica
https://www.readbyqxmd.com/read/28536947/brainstem-nuclei-changes-in-migraine-detected-by-transcranial-sonography
#10
Katarina Blažina, Darija Mahović-Lakušić, Maja Relja
The aim of this study was to estimate the role of transcranial sonography in detecting basal ganglia changes as structural biomarkers in migraine. Transcranial sonography was performed on Aloka prosound α-10. Semiquantitative and planimetric methods were applied when basal ganglia changes were detected. Comparison between groups was performed by unpaired Student's t test and Spearman's correlation test. We analyzed 30 migraine patients and 30 age-/sex-matched controls. Substantia nigra hyperechogenicity was detected in 36...
May 23, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28536104/development-and-validation-of-qrisk3-risk-prediction-algorithms-to-estimate-future-risk-of-cardiovascular-disease-prospective-cohort-study
#11
Julia Hippisley-Cox, Carol Coupland, Peter Brindle
Objectives To develop and validate updated QRISK3 prediction algorithms to estimate the 10 year risk of cardiovascular disease in women and men accounting for potential new risk factors.Design Prospective open cohort study.Setting General practices in England providing data for the QResearch database.Participants 1309 QResearch general practices in England: 981 practices were used to develop the scores and a separate set of 328 practices were used to validate the scores. 7.89 million patients aged 25-84 years were in the derivation cohort and 2...
May 23, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28535696/the-role-of-the-affect-heuristic-and-cancer-anxiety-in-responding-to-negative-information-about-medical-tests
#12
Laura D Scherer, Victoria A Shaffer, Tanner Caverly, Aaron M Scherer, Brian J Zikmund-Fisher, Jeffrey T Kullgren, Angela Fagerlin
OBJECTIVE: Little is known about the affective implications of communicating negative information about medical tests. This research explored how affective processes - particularly the Affect Heuristic and cancer anxiety - influence the way in which people respond to such information. DESIGN: Participants received different types of information about PSA screening for prostate cancer and magnetic resonance imaging (MRI) scans for migraine headaches. This was a 2 (Test harm information: present vs...
May 23, 2017: Psychology & Health
https://www.readbyqxmd.com/read/28534048/the-first-report-of-cadasil-in-peru-olfactory-dysfunction-on-initial-presentation
#13
Anastasia Vishnevetsky, Miguel Inca-Martinez, Karina Milla-Neyra, Danny Moises Barrientos-Iman, Ivan Cornejo-Herrera, Carlos Cosentino, Mario Cornejo-Olivas
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy (CADASIL) is a rare, heritable, small vessel vascular disease caused by mutations in the Notch3 gene that is characterized by migraines, subcortical vascular events, cognitive decline, and mood disturbances. However, many CADASIL cases present with unusual symptoms such as status epilepticus, a movement disorder, or sensory dysfunction. This study describes the clinical, genetic, and radiologic characteristics of a Peruvian family with CADASIL in which multiple family members presented with severe olfactory deficits...
December 2016: ENeurologicalSci
https://www.readbyqxmd.com/read/28533997/metoclopramide-for-acute-migraine-treatment-in-the-emergency-department-an-effective-alternative-to-opioids
#14
REVIEW
Mejdi Najjar, Tyler Hall, Blanca Estupinan
In light of recent warnings by the United States (US) Surgeon General and Centers for Disease Control (CDC) guidelines for recommending more prudent use of opioid narcotics, the search for a non-opioid alternative for aborting acute migraines is particularly relevant. The CDC also estimates the prevalence of opioid dependence may be as high as 26% among patients prescribed opioids for chronic pain, not due to cancer, in the primary care setting. Given such staggering data, it is imperative that we, as caretakers, not foster opioid dependence but rather continue to investigate non-opioid therapies for the management of acute migraines in the emergent care settings...
April 20, 2017: Curēus
https://www.readbyqxmd.com/read/28533763/is-alteration-of-tuning-property-in-cervical-vestibular-evoked-myogenic-potential-specific-for-m%C3%A3-ni%C3%A3-re-s-disease
#15
Toshihisa Murofushi, Masahito Tsubota, Ryota Suizu, Eriko Yoshimura
OBJECTIVE: The aim of this study is to show sensitivity and specificity of cervical vestibular-evoked myogenic potential (cVEMP) tuning property test to Ménière's disease (MD) in comparison with healthy controls (HC) and patients with other vestibular diseases. SUBJECTS: Totally 92 subjects (50 women and 42 men, 20-77 years of age) were enrolled in this study. Subjects were composed of 38 definite unilateral MD patients, 11 unilateral benign paroxysmal positional vertigo patients, 14 vestibular migraine patients, 19 unilateral vestibular neuritis patients, and 10 HC...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28527091/raven-coloured-progressive-matrices-in-migraine-without-aura-patients
#16
Giovanna Viticchi, Lorenzo Falsetti, Marco Bartolini, Laura Buratti, Lara Pistelli, Leandro Provinciali, Mauro Silvestrini
Conflicting results emerged from studies investigating cognitive performances in migraine patients. Based on clinical and neuroradiological aspects, the possible involvement of executive functions has been especially taken into consideration. The aim of this study was to evaluate, in a population of subjects affected by migraine without aura (MwoA), frontal lobe cognitive functions. We enrolled all the consecutive patients affected by MwoA referred to our headache centre for a first evaluation. Each patient underwent a neuropsychological evaluation including Raven coloured progressive matrices (CPM)...
May 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28527090/stroke-like-attack-first-episode-of-sporadic-hemiplegic-migraine
#17
Enrico Ferrante, Valentina Prone, Marco Longoni, Elio Clemente Agostoni
Hemiplegic migraine (HM) is a rare migraine with aura; it can be familiar or sporadic. A 46-years-old man presented left migraine followed by right hemiparesis with bilateral plantar flexion of cutaneous plantar reflex (CPR). Brain CT and CT-angiography were normal. The next day patient got worse. The EEG showed left fronto-temporal cuspidate delta waves and brain MRI showed a minimal hyperintensity at T2-sequences in the left frontal cortex with a minor representation of the cortical veins at susceptibility weighted imaging sequences...
May 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28527089/pediatric-migraine-with-aura-in-an-italian-case-series
#18
Arens Taga, Marco Russo, Antonio Genovese, Maria Vittoria Paglia, Gian Camillo Manzoni, Paola Torelli
The aim of the present study was to describe the characteristics of migraine with aura (MwA) in a case series of patients with headache onset before 12 years of age. We considered all consecutive patients referred to the Parma Headache Centre between 1975 and 2015 affected by MwA, diagnosed by our team of trained neurologists; the cases were subsequently reviewed applying the ICHD3-beta criteria. We then identified those cases with headache age-of-onset <12 years (i.e., "pediatric" cases), which were compared to all remaining cases...
May 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28527087/migraine-with-aura-and-white-matter-lesions-an-mri-study
#19
Carla Uggetti, Silvia Squarza, Fabio Longaretti, Alberto Galli, Paola Di Fiore, Paolo Filippo Reganati, Adriana Campi, Andreana Ardemagni, Maurizio Cariati, Fabio Frediani
Several studies report the presence of white matter lesions on brain magnetic resonance imaging in patients with migraine. The aim of our study was to detect the entity of white matter T2-hyperintensities in 90 high selected patients affected by migraine with aura, compared to a group of 90 healthy controls. We found no significant difference of incidence of white matter alterations comparing these two groups.
May 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28527086/non-invasive-vagus-nerve-stimulation-nvns-as-symptomatic-treatment-of-migraine-in-young-patients-a-preliminary-safety-study
#20
Licia Grazzi, Gabriella Egeo, Eric Liebler, Anna Maria Padovan, Piero Barbanti
Recent clinical experiences and clinical trials have demonstrated the safety, tolerability, and efficacy of non-invasive vagus nerve stimulation (nVNS; gammaCore(®)) for the acute and prophylactic treatment of migraine. nVNS has a favorable adverse event profile, making it an attractive option for sensitive patient populations. We explored the safety, tolerability, and efficacy of nVNS as acute migraine treatment in adolescents. A group of adolescent patients suffering from migraine without aura were trained to use gammaCore to manage their migraine attacks...
May 2017: Neurological Sciences
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