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https://www.readbyqxmd.com/read/28448400/comparison-of-the-performance-between-sepsis-1-and-sepsis-3-in-icus-in-china-a-retrospective-multicenter-study
#1
Baoli Cheng, Zhongwang Li, Jingya Wang, Guohao Xie, Xu Liu, Zhipeng Xu, Lihua Chu, Jialian Zhao, Yongming Yao, Xiangming Fang
The definition of sepsis was updated to sepsis-3 in February 2016. However, the performance of the previous and new definition of sepsis remains unclear in China. This was a retrospective multicenter study in 6 ICUs from 5 university-affiliated hospitals to compare the performance between sepsis-1 and sepsis-3 in China. From May 1, 2016 to June 1, 2016, 496 patients were enrolled consecutively. Data were extracted from the electronic clinical records. We evaluated the performance of sepsis-1 and sepsis-3 by measuring the area under the receiver operating characteristic curves (AUROC) to predict 28-day mortality rates...
April 26, 2017: Shock
https://www.readbyqxmd.com/read/28446375/giant-lipoma-extending-into-two-thigh-canals-a-case-report
#2
Melike Gungor, Emin Sir, Alper Aksoy, Sule Agirbas
Giant lipomas, although rare, represent a real diagnostic and therapeutic challenge. We report an unusual giant lipoma of the thigh extending into two thigh canals and it's diagnostic and therapeutic processes.
April 23, 2017: Acta Orthopaedica et Traumatologica Turcica
https://www.readbyqxmd.com/read/28445537/predicting-epidemic-evolution-on-contact-networks-from-partial-observations
#3
Jacopo Bindi, Alfredo Braunstein, Luca Dall'Asta
The massive employment of computational models in network epidemiology calls for the development of improved inference methods for epidemic forecast. For simple compartment models, such as the Susceptible-Infected-Recovered model, Belief Propagation was proved to be a reliable and efficient method to identify the origin of an observed epidemics. Here we show that the same method can be applied to predict the future evolution of an epidemic outbreak from partial observations at the early stage of the dynamics...
2017: PloS One
https://www.readbyqxmd.com/read/28442215/-neopterin-levels-and-systemic-inflammatory-response-syndrome-in-pediatric-critically-ill-patients
#4
Raquel Gil-Gómez, Javier Blasco-Alonso, Pilar Sánchez-Yáñez, Vanessa Rosa-Camacho, Guillermo Milano Manso
INTRODUCTION: Neopterin and biopterin are sub-products of redox reactions, which act as cofactors of enzymes responsible for nitric oxide production. The hypothesis is presented that plasma neopterin and biopterin evolve differently during the first days in a critically ill child. METHODS: A single-centre prospective observational study was conducted on patients 7 days to 14 years admitted to our Paediatric Intensive Care Unit (PICU) and that met Systemic inflammatory response syndrome (SIRS) criteria...
April 22, 2017: Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría (A.E.P.)
https://www.readbyqxmd.com/read/28442169/cochlear-implantation-in-children-with-anomalous-cochleovestibular-anatomy
#5
REVIEW
Ana Sofia Melo, Jorge Martins, João Silva, Jorge Quadros, António Paiva
OBJECTIVE: The aim of the study is to assess the audiological and surgical outcome after cochlear implantation in children with inner ear malformation and to compare them with a group of congenitally deaf children implantees without inner ear malformation. INTRODUCTION: Children with profound sensorineural deafness with malformations of the inner ear represent a challenge, accounting to 5-15% of congenital sensorineural deafness. These cases were originally regarded as a contraindication for cochlear implant surgery...
April 22, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/28441935/direct-and-indirect-effects-of-influenza-vaccination
#6
Martin Eichner, Markus Schwehm, Linda Eichner, Laetitia Gerlier
BACKGROUND: After vaccination, vaccinees acquire some protection against infection and/or disease. Vaccination, therefore, reduces the number of infections in the population. Due to this herd protection, not everybody needs to be vaccinated to prevent infections from spreading. METHODS: We quantify direct and indirect effects of influenza vaccination examining the standard Susceptible-Infected-Recovered (SIR) and Susceptible-Infected-Recovered-Susceptible (SIRS) model as well as simulation results of a sophisticated simulation tool which allows for seasonal transmission of four influenza strains in a population with realistic demography and age-dependent contact patterns...
April 26, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28441174/increased-incidence-of-cancer-observed-in-hiv-hepatitis-c-virus-coinfected-patients-versus-hiv-monoinfected
#7
Héctor Meijide, Sonia Pértega, Iria Rodríguez-Osorio, Ángeles Castro-Iglesias, Josefa Baliñas, Guillermo Rodríguez-Martínez, Álvaro Mena, Eva Poveda
BACKGROUND: Cancer is a growing problem in persons living with HIV infection (PLWH) and hepatitis C virus (HCV) coinfection could play an additional role in carcinogenesis. Herein, all cancers in an HIV-mono and HIV/HCV-coinfected cohort were evaluated and compared to identify any differences between these two populations. METHODS: A retrospective cohort study was conducted including all cancers in PLWH between 1993 and 2014. Cancers were classified in two groups: AIDS-defining cancer (ADC) and non-AIDS-defining cancer (NADC)...
May 15, 2017: AIDS
https://www.readbyqxmd.com/read/28440347/performance-of-2d-swe-ge-for-predicting-different-stages-of-liver-fibrosis-using-transient-elastography-as-the-reference-method
#8
Felix Bende, Ioan Sporea, Roxana Sirli, Alina Popescu, Ruxandra Mare, Bogdan Miutescu, Raluca Lupusoru, Tudor Moga, Corina Pienar
AIM: To evaluate the performance of 2D shear-wave elastography from General Electric (2D-SWE.GE) for the noninvasiveassessment of liver fibrosis and to identify liver stiffness (LS) cut-off values for predicting different stages of fibrosisusing Transient Elastography (TE) as the reference method. MATERIAL AND METHOD: We included 331 consecutive subjectswith or without chronic hepatopathies in whom LS was evaluated in the same session by means of 2 elastographic techniques:TE and 2D-SWE...
April 22, 2017: Medical Ultrasonography
https://www.readbyqxmd.com/read/28436631/-video-head-impulse-test-for-evaluation-of-vestibular-function-in-patients-with-vestibular-neuritis-and-benign-paroxysmal-positional-vertigo
#9
Qiongfeng Guan, Lisan Zhang, Wenke Hong, Yi Yang, Zhaoying Chen, Dan Zhang, Xingyue Hu
Objective: To assess the clinical application of video head impulse test (vHIT) for vestibular function in vestibular neuritis (VN) and benign paroxysmal positional vertigo (BPPV) patients. Methods: Thirty-three patients with VN and 43 patients with BPPV were enrolled from Sir Run Run Shaw Hospital and Ningbo Second Hospital from March 15 to September 10, 2015; and 50 healthy controls were also enrolled in the study. vHIT was used to quantitatively test the vestibulo-ocular reflex (VOR) gains of a pair of horizontal semicircular canals...
January 25, 2017: Zhejiang da Xue Xue Bao. Yi Xue Ban, Journal of Zhejiang University. Medical Sciences
https://www.readbyqxmd.com/read/28434995/an-sir-dengue-transmission-model-with-seasonal-effects-and-impulsive-control
#10
Joseph Páez Chávez, Thomas Götz, Stefan Siegmund, Karunia Putra Wijaya
In recent decades, Dengue fever and its deadly complications, such as Dengue hemorrhagic fever, have become one of the major mosquito-transmitted diseases, with an estimate of 390 million cases occurring annually in over 100 tropical and subtropical countries, most of which belonging to the developing world. Empirical evidence indicates that the most effective mechanism to reduce Dengue infections is to combat the disease-carrying vector, which is often implemented via chemical pesticides to destroy mosquitoes in their adult or larval stages...
April 20, 2017: Mathematical Biosciences
https://www.readbyqxmd.com/read/28434024/chaotic-dynamics-in-the-seasonally-forced-sir-epidemic-model
#11
Pablo G Barrientos, J Ángel Rodríguez, Alfonso Ruiz-Herrera
We prove analytically the existence of chaotic dynamics in the forced SIR model. Although numerical experiments have already suggested that this model can exhibit chaotic dynamics, a rigorous proof (without computer-aided) was not given before. Under seasonality in the transmission rate, the coexistence of low birth and mortality rates with high recovery and transmission rates produces infinitely many periodic and aperiodic patterns together with sensitive dependence on the initial conditions.
April 22, 2017: Journal of Mathematical Biology
https://www.readbyqxmd.com/read/28433462/-health-and-access-to-health-care-of-18-25%C3%A2-years-old-people-not-in-employment-education-or-training-neets-attending-the-french-missions-locales
#12
S Robert, S Lesieur, J Chastang, V Kergoat, J Dutertre, P Chauvin
BACKGROUND: In France, "missions locales" are public assistance units for young people aged 16-25 years not in employment, education or training (NEET). The health status of the more than 1.5 million young adults attending these units annually is unknown. The purpose of this study was to describe the health status and health care use of this population in comparison with the general population of the same age. METHODS: The Presaje survey was conducted in 2011 on a randomized sample of 1453 young adults aged 18-25 years who attended five "missions locales" in mainland France...
April 19, 2017: Revue D'épidémiologie et de Santé Publique
https://www.readbyqxmd.com/read/28429472/transoral-orthodromic-temporalis-muscle-transfer-technique-for-the-paralysed-midface-our-learning-curve-experience-from-the-first-10-cases
#13
Lepa Lazarova, Tristram H Lesser, Samuel C Leong
Sir Harold Gillies first described rotating a band of temporalis muscle over the zygoma where the muscle sling was augmented with strips of fascia lata to rehabilitate facial paralysis (1) . McLaughlin later modified this technique in the 1950s without inversion of the temporal muscle but in an orthodromic manner thus avoiding the soft tissue fullness over the zygomatic arch area and depression of the donor site (2) . Although several refinements of this technique have been described, all required skin incisions on the face until a transoral technique was described recently by this clinical group (3) ...
April 21, 2017: Clinical Otolaryngology
https://www.readbyqxmd.com/read/28427707/incidence-of-multiple-sclerosis-in-the-republic-of-ireland-a-prospective-population-based-study
#14
K O'Connell, N Tubridy, M Hutchinson, C McGuigan
BACKGROUND: Multiple sclerosis (MS) incidence and prevalence is increasing worldwide, with a disproportionally higher rate in women. Recent studies have questioned the presence of a latitudinal gradient in Europe. Ireland is a high prevalence country for MS with a previously reported North-South gradient making it ideal to further explore this concept. OBJECTIVES: In this study we prospectively determined the incidence rate of newly diagnosed MS in Ireland over a 12-month period and demonstrated the presence of a North-South gradient...
April 2017: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/28426775/dynamic-behaviors-of-a-modified-sir-model-in-epidemic-diseases-using-nonlinear-incidence-and-recovery-rates
#15
Gui-Hua Li, Yong-Xin Zhang
The transmission of infectious diseases has been studied by mathematical methods since 1760s, among which SIR model shows its advantage in its epidemiological description of spread mechanisms. Here we established a modified SIR model with nonlinear incidence and recovery rates, to understand the influence by any government intervention and hospitalization condition variation in the spread of diseases. By analyzing the existence and stability of the equilibria, we found that the basic reproduction number [Formula: see text] is not a threshold parameter, and our model undergoes backward bifurcation when there is limited number of hospital beds...
2017: PloS One
https://www.readbyqxmd.com/read/28421722/second-primary-cancer-risk-among-kidney-cancer-patients-in-korea-a-population-based-cohort-study
#16
Jae Young Joung, Whi-An Kwon, Jiwon Lim, Chang-Mo Oh, Kyu-Won Jung, Sung Han Kim, Ho Kyung Seo, Weon Seo Park, Jinsoo Chung, Kang Hyun Lee, Young-Joo Won
Purpose: Secondary primary cancers (SPCs) commonly arise in patients with renal cell carcinoma (RCC). We designed the present study to estimate the SPC incidence in Korean patients with RCC. Materials and Methods: The study cohort was population-based and consisted of 40,347 individuals from the Korean Central Cancer Registry who were diagnosed with primary renal cancer between 1993 and 2013. Standardized incidence ratios (SIRs) for SPCs were estimated for different ages at diagnosis, latencies, diagnostic periods, and treatments...
April 19, 2017: Cancer Research and Treatment: Official Journal of Korean Cancer Association
https://www.readbyqxmd.com/read/28420465/-clinical-value-of-serum-endocan-and-procalcitonin-in-early-diagnosis-and-prognosis-evaluation-of-sepsis
#17
Rong Zhao, Shimin Dong
OBJECTIVE: To investigate the clinical value of serum endocan and procalcitonin (PCT) in early diagnosis and prognosis evaluation of sepsis. METHODS: The patients with systemic inflammatory response syndrome (SIRS, n = 26) and sepsis (n = 78) admitted to intensive care unit (ICU) of the Third Hospital of Hebei Medical University from December 2014 to December 2016 were enrolled. According to the severity of disease, the sepsis patients were divided into general sepsis group (n = 20), severe sepsis group (n = 24), and septic shock group (n = 34)...
April 2017: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://www.readbyqxmd.com/read/28420038/retrospective-evaluation-of-coyote-attacks-in-dogs-154-cases-1997-2012
#18
Virginia M Frauenthal, Philip Bergman, Robert J Murtaugh
OBJECTIVE: To describe the clinical presentation and outcome of known attacks in client-owned dogs caused by the common coyote, Canis latrans. DESIGN: Retrospective observational study. SETTING: Private referral hospital. ANIMALS: One hundred fifty-four client-owned dogs known to be attacked by coyotes. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: Records from a private referral hospital from May 1997 through December 2012 were reviewed...
April 18, 2017: Journal of Veterinary Emergency and Critical Care
https://www.readbyqxmd.com/read/28418807/coagulase-negative-staphylococci-in-human-milk-from-mothers-of-preterm-compared-with-term-neonates
#19
Hiie Soeorg, Tuuli Metsvaht, Imbi Eelmäe, Hanna Kadri Metsvaht, Sirli Treumuth, Mirjam Merila, Mari-Liis Ilmoja, Irja Lutsar
BACKGROUND: Human milk is the preferred nutrition for neonates and a source of bacteria. Research aim: The authors aimed to characterize the molecular epidemiology and genetic content of staphylococci in the human milk of mothers of preterm and term neonates. METHODS: Staphylococci were isolated once per week in the 1st month postpartum from the human milk of mothers of 20 healthy term and 49 preterm neonates hospitalized in the neonatal intensive care unit. Multilocus variable-number tandem-repeats analysis and multilocus sequence typing were used...
May 2017: Journal of Human Lactation: Official Journal of International Lactation Consultant Association
https://www.readbyqxmd.com/read/28418697/a-two-biomarker-model-predicts-mortality-in-the-critically-ill-with-sepsis
#20
Carmen Mikacenic, Brenda L Price, Susanna Harju-Baker, D Shane O'Mahony, Cassianne Robinson-Cohen, Frank Radella, William O Hahn, Ronit Katz, David C Christiani, Jonathan Himmelfarb, W Conrad Liles, Mark M Wurfel
RATIONALE: Improving the prospective identification of patients with the systemic inflammatory response syndrome (SIRS) and sepsis at low for organ dysfunction and death is a major clinical challenge. OBJECTIVE: To develop and validate a multi-biomarker based prediction model for 28-day mortality in critically ill patients with SIRS and sepsis. METHODS: The derivation cohort (n=888) and internal test cohort (n=278) were from a prospective study of critically ill intensive care unit (ICU) patients meeting 2 of 4 SIRS criteria at an academic medical center for whom plasma was obtained within 24 hours...
April 18, 2017: American Journal of Respiratory and Critical Care Medicine
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