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Zhenteng Li, Brian Curtis, Robert Layser, Santosh Kumar Selvarajan, James Harrop, Lawrence C Kenyon, Theodore Parsons, Asa Rubin
A 69-year-old woman presented with bilateral upper-extremity radiculopathy and neck pain after a mechanical fall. Admission CT and MRI of the cervical spine demonstrated a pathological C-4 fracture. Subsequent malignancy workup was negative. A CT-guided biopsy of the lesion showed intraosseous hemangioblastoma. Hemangioblastoma is a highly vascular, slow-growing tumor of the CNS; intraosseous location of this tumor is extremely rare. The authors review the diversity of its presentation and the treatment techniques of this rare tumor in an extremely rare location...
September 2017: Journal of Neurosurgery. Spine
Robert B Layser, Michael P Savage, Ethan J Halpern
RATIONALE AND OBJECTIVES: The study aimed to evaluate the association of a coronary interarterial course (IAC) with adverse outcomes in adults and to assess the benefit of coronary artery bypass grafting (CABG) in this population. MATERIALS AND METHODS: A retrospective review identified 172 adults over 40 years of age with an anomalous coronary artery origin from the opposite coronary sinus, including 79 patients with an IAC. Hard outcomes (myocardial infarction or cardiac death) and soft outcomes (persistent angina) were evaluated, with a mean follow-up time of 5 years...
August 2016: Academic Radiology
J A Stryker, C K Chung, J D Layser
Thirty-three patients were randomized prior to pelvic radiotherapy to receive the bile acid-sequestering resin colestipol hydrochloride, 5 grams qid, during the entire time of their therapy or diphenoxylate hydrochloride and atropine sulfate 2.5-20 mg per day (control) if they experienced diarrhea. The colestipol patients also took diphenoxylate if they had diarrhea. The patients in the colestipol group often experienced nausea, vomiting, and abdominal cramps and 8 were forced to discontinue the drug. There was no difference in the weekly stool frequency between the colestipol and the control patients but the colestipol patients who took at least 50% of the prescribed dose required fewer diphenoxylate tablets than the controls...
February 1983: International Journal of Radiation Oncology, Biology, Physics
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