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https://www.readbyqxmd.com/read/29779644/development-of-a-novel-tissue-engineered-nitinol-frame-artificial-trachea-with-native-like-physical-characteristics
#1
Yasuto Sakaguchi, Toshihiko Sato, Yusuke Muranishi, Yojiro Yutaka, Teruya Komatsu, Koichi Omori, Tatsuo Nakamura, Hiroshi Date
BACKGROUND: Tracheal reconstruction is complicated by the short length to which a trachea can be resected. We previously developed a biocompatible polypropylene frame artificial trachea, but it lacked the strength and flexibility of the native trachea. In contrast, nitinol may provide these physical characteristics. We developed a novel nitinol frame artificial trachea and examined its biocompatibility and safety in canine models. METHODS: We constructed several nitinol frame prototypes and selected the frame that most closely reproduced the strength of the native canine trachea...
April 24, 2018: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29774857/influenza-d-virus-infection-in-feral-swine-populations-united-states
#2
Lucas Ferguson, Kaijian Luo, Alicia K Olivier, Fred L Cunningham, Sherry Blackmon, Katie Hanson-Dorr, Hailiang Sun, John Baroch, Mark W Lutman, Bianca Quade, William Epperson, Richard Webby, Thomas J DeLiberto, Xiu-Feng Wan
Influenza D virus (IDV) has been identified in domestic cattle, swine, camelid, and small ruminant populations across North America, Europe, Asia, South America, and Africa. Our study investigated seroprevalence and transmissibility of IDV in feral swine. During 2012-2013, we evaluated feral swine populations in 4 US states; of 256 swine tested, 57 (19.1%) were IDV seropositive. Among 96 archived influenza A virus-seropositive feral swine samples collected from 16 US states during 2010-2013, 41 (42.7%) were IDV seropositive...
June 2018: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/29773094/replication-and-pathology-of-duck-influenza-virus-subtype-h9n2-in-chukar
#3
Yin Chuan Zhu, Bin Zhang, Zeng Hui Sun, Xi Jing Wang, Xiao Hui Fan, Ling Xi Gao, Ying Liang, Xiao Yan Chen, Zeng Feng Zhang
To investigate the susceptibility of Chukars to duck avian influenza virus H9N2 and explore their role in interspecies transmission of influenza viruses. Chukars were inoculated with duck avian influenza viruses H9N2. The present study demonstrated that inflammatory lesions and virus antigen were present in the trachea, bronchus, and parabronchus, and the viruses could be isolated from throat swabs and lung tissue homogenate supernatants. At 14 d post virus inoculation, anti-H9 influenza virus antibody in the serum was detected...
April 2018: Biomedical and Environmental Sciences: BES
https://www.readbyqxmd.com/read/29771610/tracheal-acid-or-surfactant-instillation-raises-alveolar-surface-tension
#4
Tam L Nguyen, Carrie E Perlman
Whether alveolar liquid surface tension, T, is elevated in the acute respiratory distress syndrome (ARDS) has not been demonstrated in situ in the lungs. Neither is it known how exogenous surfactant, which has failed to treat ARDS, affects in situ T. We aim to determine T in an acid-aspiration ARDS model before and after exogenous surfactant administration. In isolated rat lungs, we combine servo-nulling pressure measurement and confocal microscopy to determine alveolar liquid T according to the Laplace relation...
May 17, 2018: Journal of Applied Physiology
https://www.readbyqxmd.com/read/29771053/-arytenoid-dislocation-after-trachea-foreign-body-surgery-one-case-report
#5
Y F Ji, J Liu, R R Yin, X Chen, D L Jin
One case of arytenoids dislocation after removal of a foreign body from the trachea was reported. After operation, throat pain, hoarseness and laborious speech, arytenoids dislocation was revealed by electronic laryngoscopy.
May 20, 2017: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://www.readbyqxmd.com/read/29771052/-a-case-of-schwannoma-in-cervical-trachea
#6
X Q Shi, J F Luo, Y Yang, X Chen, W S Qu, Y B Wang, F B Cheng
Primary tracheal schwannoma is rare. It is easy to be misdiagnosed as bronchitis, asthma due to the lack of special symptom. Diagnosis of schwannoma depends on a comprehensive examination. Surgery is the only effective mean. Here we reported a 17-year-old male, who suffered from cough for 10 months. A variety of tests confirmed that he had schwannoma. There is no significant change after tumor resection via rigid bronchoscope since two years ago.
May 20, 2017: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://www.readbyqxmd.com/read/29771049/-a-case-report-of-tracheotomy-complicated-by-hemorrhage-after-radical-operation-of-tongue
#7
M Y Sun, H J Wu
A 55-year old middle-aged male presented swelling lymph nodes in neck and mass in left tongue for three mouths. Physical examination shows a size 5 cm×5 cm mass in tongue and went over the midline. The mandibular lymph nodes were touched with moderate tenderness and little mobility in bilateral. The laboratory results, function of the kidney and heart liver, nasopharyngeal fiber area were basically normal. The result of CT and MRI shows the mass reached the lingual muscle layer and several suspected metastatic lymph nodes in neck...
May 20, 2017: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://www.readbyqxmd.com/read/29769502/variation-of-luminal-diameter-of-the-right-principal-bronchus-in-different-age-and-sex-group-of-bangladeshi-cadaver
#8
N Nawshin, S Mannan, M F Kamal, E Z Epsi, Z Ahmed
The respiratory system is involved in the intake and exchange of oxygen and carbon dioxide between an organism and the environment which is essential for human survival. The bronchial tree includes the trachea, right and left principal bronchi and their branching upto alveoli. A common medical problem with the respiratory tract is acute respiratory tract infection (ARI) which is the leading killer of children under five. The aim of the present study was to find out the variation of the luminal diameter of right principal bronchus in Bangladeshi people...
April 2018: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/29768944/zataria-multiflora-essential-oil-reduces-replication-rate-of-avian-influenza-virus-h9n2-subtype-in-challenged-broiler-chicks
#9
Arzhang Shayeganmehr, Mehdi Vasfi Marandi, Vahid Karimi, Abbas Barin, Arash Ghalyanchi-Langeroudi
The effect of Zataria multiflora essential oil on replication rate of the H9N2 virus in target organs was determined by real-time PCR. One-day-old broiler chicks were randomly divided into six groups and were challenged with H9N2 influenza. Two groups received either 20 or 40 µl/kg body weight/day Zataria multiflora essential oils (ZM) seven days before the challenge while two other groups received the essential oil at the same dosage but after H9N2 challenge. One group received 4 mg/kg body weight/day of the anti-viral compound amantadine after challenge and the last group received no treatment and served as the control...
May 17, 2018: British Poultry Science
https://www.readbyqxmd.com/read/29768342/mucosa-associated-lymphoid-tissue-lymphoma-of-the-trachea-associated-with-idiopathic-pulmonary-fibrosis-a-case-report-and-literature-review
#10
June Hong Ahn, Jin Hong Chung, Kyeong-Cheol Shin, Eun Young Choi, Hyun Jung Jin, Joon Hyuk Choi, Kwan Ho Lee
RATIONALE: Mucosa-associated lymphoid tissue (MALT) lymphoma of the trachea is a rare disease that has been shown to be associated with chronic antigenic stimulation. There have been few reports of MALT lymphoma of the trachea in association with idiopathic pulmonary fibrosis (IPF). PATIENT CONCERNS: A 73-year-old patient visited with a 2-year history of dyspnea on exertion and productive cough, which had worsened 1 month ago. DIAGNOSES: MALT lymphoma of the trachea associated with IPF...
May 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29767634/measurement-and-estimation-of-human-forced-expiratory-noise-parameters-using-a-microphone-with-a-stethoscope-head-and-a-lapel-microphone
#11
Anna Yur'evna Glazova, Vladimir I Korenbaum, Anatoly E Kostiv, Oksana I Kabancova, Alexander A Tagiltcev, Svetlana N Shin
The time signature of tracheal noise in the 200-2000 Hz frequency band recorded during a forced expiratory manoeuvre (FETa) is a promising tool for diagnosis of bronchial obstructions. FETa is typically registered using a microphone with a stethoscope head placed on the neck over the trachea (stethoscope sensor). We studied basic time and spectral parameters of forced expiratory tracheal noises with a microphone placed near the mouth (lapel microphone, outside the flow of exhaled air) and compared these with measurements via stethoscope sensor, with the aim of providing patient home monitoring via standard personal computer facilities...
May 16, 2018: Physiological Measurement
https://www.readbyqxmd.com/read/29765893/successful-management-of-acquired-tracheomalacia-of-patients-with-amyotrophic-lateral-sclerosis-a-report-of-three-cases
#12
Jung Hyun Yang, Tae Wan Kim, Byeong Ju Lee, Jin A Yoon, Myung Jun Shin, Yong Beom Shin
Tracheomalacia is characterized by weakness of the tracheal walls and supporting cartilage. It results in dynamic compression of the airway, where the cross-sectional area of the trachea is reduced by expiratory compression. Acquired tracheomalacia results from complications associated with the use of endotracheal or tracheostomy tubes. In this report, we present three cases of patients with amyotrophic lateral sclerosis (ALS) successfully treated for tracheomalacia, including one case where the patient underwent surgery for combined tracheoesophageal fistula...
April 2018: Annals of Rehabilitation Medicine
https://www.readbyqxmd.com/read/29765640/vascularization-of-the-trachea-in-the-bottlenose-dolphin-comparison-with-bovine-and-evidence-for-evolutionary-adaptations-to-diving
#13
Cristina Ballarin, Paola Bagnoli, Antonella Peruffo, Bruno Cozzi
The rigid structure of the mammalian trachea is functional to maintain constant patency and airflow during breathing, but no gas exchange takes place through its walls. The structure of the organ in dolphins shows increased rigidity of the tracheal cartilaginous rings and the presence of vascular lacunae in the submucosa. However, no actual comparison was ever made between the size and capacity of the vascular lacunae of the dolphin trachea and the potentially homologous structures of terrestrial mammals. In the present study, the extension of the lacunae has been compared between the bottlenose dolphin and the bovine, a closely related terrestrial Cetartiodactyla...
April 2018: Royal Society Open Science
https://www.readbyqxmd.com/read/29765235/fatal-hemoptysis-in-patients-with-advanced-esophageal-cancer-treated-with-apatinib
#14
Wei Wang, Lin Zhang, Yan Xie, Tianchang Zhen, Gongzhang Su, Qi Zang
Targeted therapy is commonly used for treating advanced malignant tumors. Compared with cytotoxic drugs, targeted drugs have the characteristics of good curative results, less adverse effects, and convenient oral administration. Hence, they are especially suitable for patients with cancer who are not able to tolerate chemotherapy. Anti-angiogenic therapy can achieve the objective by inhibiting the formation of new blood vessels in tumors. Apatinib is a novel tyrosine kinase inhibitor targeting the intracellular domain of vascular endothelial growth factor receptor-2...
2018: OncoTargets and Therapy
https://www.readbyqxmd.com/read/29763597/a-hem-o-lok-induced-tracheoesophageal-fistula-cured-by-temporary-airway-stenting-modified-with-three-dimensional-printing
#15
Yichao Han, Su Yang, Wei Huang, Zhongmin Wang, Hecheng Li
We present the case of a fistula between the trachea and the esophagogastric anastomosis in a 58-year-old male after esophagectomy. A Hem-o-Lok clip used at the time to ligate the azygos vein was discovered by esophagoscopy and bronchoscopy to be eroding into the both structures. A covered self-expandable Y-shaped metallic tracheobronchial stent was customized with a 3D printed airway model and inserted in place, with endoscopic injection of fibrin glue to the anastomotic site. 64 days after implantation, the stent was withdrawn with complete healing of the fistula...
May 12, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29763253/croup-diagnosis-and-management
#16
Dustin K Smith, Andrew J McDermott, John F Sullivan
Croup is a common respiratory illness affecting 3% of children six months to three years of age. It accounts for 7% of hospitalizations annually for fever and/or acute respiratory illness in children younger than five years. Croup is a manifestation of upper airway obstruction resulting from swelling of the larynx, trachea, and bronchi, leading to inspiratory stridor and a barking cough. Many patients experience low-grade fevers, but fever is not necessary for diagnosis. Less commonly, stridor can be associated with acute epiglottitis, bacterial tracheitis, and foreign body airway obstruction...
May 1, 2018: American Family Physician
https://www.readbyqxmd.com/read/29762877/visualisation-of-insect-tracheal-systems-by-lactic-acid-immersion
#17
Y Ruan, Y Li, M Zhang, X Chen, Z Liu, S Wang, S Jiang
The endeavours to reveal the tracheal system of insects and some arachnids has a long history. The traditional way to observe a tracheal system in an insect body is by utilising the glycerin immersion method. In this study, we developed the lactic acid immersion method, which reveals a more complete tracheal system. By mounting various types of live specimens or body parts directly into lactic acid, multiple intact and complex tracheal systems were clearly visualised. The lactic acid immersion contributed to revealing tracheal systems by penetrating body tissue while reserving enough time for observation before the penetration of the tracheae...
May 15, 2018: Journal of Microscopy
https://www.readbyqxmd.com/read/29761867/airway-physical-examination-tests-for-detection-of-difficult-airway-management-in-apparently-normal-adult-patients
#18
REVIEW
Dominik Roth, Nathan L Pace, Anna Lee, Karen Hovhannisyan, Alexandra-Maria Warenits, Jasmin Arrich, Harald Herkner
BACKGROUND: The unanticipated difficult airway is a potentially life-threatening event during anaesthesia or acute conditions. An unsuccessfully managed upper airway is associated with serious morbidity and mortality. Several bedside screening tests are used in clinical practice to identify those at high risk of difficult airway. Their accuracy and benefit however, remains unclear. OBJECTIVES: The objective of this review was to characterize and compare the diagnostic accuracy of the Mallampati classification and other commonly used airway examination tests for assessing the physical status of the airway in adult patients with no apparent anatomical airway abnormalities...
May 15, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29757925/a-modified-co2-o2-guedel-airway-improves-capnographic-accuracy-compared-with-a-co2-o2-nasal-cannula-an-infant-manikin-study
#19
Jens Moll, Pinelopi Anagnostopoulou, Franz J Frei, Thomas O Erb
BACKGROUND: Capnography via a CO2/O2 nasal cannula is commonly used for respiratory monitoring during sedation. However, signal disturbances are frequently encountered, especially in young children. OBJECTIVE: Sampling ports placed closer to the trachea have been shown to result in improved signal quality. In a manikin model of a 6-month-old infant we compared capnography from a modified Guedel airway with a CO2 port located at the tip with that from a CO2/O2 nasal cannula...
April 30, 2018: European Journal of Anaesthesiology
https://www.readbyqxmd.com/read/29756744/monitoring-the-oxygen-reserve-index-can-contribute-to-the-early-detection-of-deterioration-in-blood-oxygenation-during-one-lung-ventilation
#20
Wakana Koishi, Motoi Kumagai, Shohei Ogawa, Shuhei Hongo, Kenji Suzuki
BACKGROUND: Hypoxemia can occur during one-lung ventilation (OLV), but monitoring blood oxygenation using percutaneous oxygen saturation (SpO2) can be limited by detection latency, and SpO2 sometimes does not change during OLV. The Oxygen Reserve Index (ORiTM) is a novel index reported to detect impending desaturation before this is observed with SpO2 monitoring. This study assessed whether the ORi decreased earlier than SpO2 during OLV and evaluated its correlation with the partial pressure of arterial oxygen (PaO2) during OLV...
May 14, 2018: Minerva Anestesiologica
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