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https://www.readbyqxmd.com/read/28812530/feline-herpesvirus-pneumonia-investigations-into-the-pathogenesis
#1
Josep Maria Monne Rodriguez, Gail Leeming, Kernt Köhler, Anja Kipar
Feline herpesvirus type 1 (FeHV-1) is one of the etiological agents of feline respiratory disease. FeHV-1 is an epitheliotropic and cytopathic virus that mainly causes rhinitis and conjunctivitis, although pneumonia is also occasionally seen. In this study, the authors investigated the pathogenesis of FeHV-1-associated pneumonia, comparing natural cases with viral infection of tracheal ring and cell cultures in vitro, using histology, immunohistology, double immunofluorescence, and transmission electron microscopy as investigative tools...
January 1, 2017: Veterinary Pathology
https://www.readbyqxmd.com/read/28811940/recurrent-wheezing-and-cough-caused-by-double-aortic-arch-not-asthma
#2
Qiao Zhang, Zhou Fu, Jihong Dai, Gang Geng, Wenlong Fu, Daiyin Tian
INTRODUCTION: Double aortic arch is a congenital vascular abnormality in which the connected segments and their branches course between and compress the trachea and esophagus, often resulting in invariable airway compression. CASE PRESENTATION: A 4-year-old boy with a history of recurrent wheezing was admitted to our hospital for evaluation of asthma based on his past medical history, persistent cough, wheezing, and airway hyperresponsiveness by lung function test...
2017: Case Reports in Cardiology
https://www.readbyqxmd.com/read/28811312/myosin-ii-is-not-required-for-drosophila-tracheal-branch-elongation-and-cell-intercalation
#3
Amanda Ochoa-Espinosa, Stefan Harmansa, Emmanuel Caussinus, Markus Affolter
The Drosophila tracheal system consists of an interconnected network of monolayered epithelial tubes that ensures oxygen transport in the larval and adult body. During tracheal dorsal branch (DB) development, individual DBs elongate as a cluster of cells, led by tip cells at the front and trailing cells in the rear. Branch elongation is accompanied by extensive cell intercalation and cell lengthening of the trailing stalk cells. Although cell intercalation is governed by Myosin II (MyoII)-dependent forces during tissue elongation in the Drosophila embryo that lead to germ-band extension, it remained unclear whether MyoII plays a similar active role during tracheal branch elongation and intercalation...
August 15, 2017: Development
https://www.readbyqxmd.com/read/28811222/antitussive-antispasmodic-bronchodilating-and-cardiac-inotropic-effects-of-the-essential-oil-from-blepharocalyx-salicifolius-leaves
#4
Jehison Jiménez Hernández, María Inés Ragone, Patricia Bonazzola, Arnaldo L Bandoni, Alicia E Consolini
ETHOPHARMACOLOGY RELEVANCE: Blepharocalyx salicifolius (Kunth) O. Berg (Myrtaceae) is a tree native to Argentina and Uruguay that grows and is cultivated along the riverside of the Rio de la Plata. The leaves of this plant species, locally known as "anacahuita" are used in South America to prepare infusions for the empiric treatment of cough and bronchospasm, as well as diarrhoea and other intestinal disorders. Although previous phytochemical studies have been performed with the essential oil extracted from Blepharocalyx salicifolius, pharmacological evidence supporting its traditional use is still lacking...
August 12, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28805043/fatal-peste-des-petits-ruminants-disease-in-chowsingha
#5
S Jaisree, R P Aravindhbabu, P Roy, M G Jayathangaraj
This communication reports fatal Peste des petits ruminants (PPR) disease in Chowsingha (Tetracerus quadricornis), a member of the subfamily Bovinae and family Bovidae captured in a Zoological Park. The animals showed clinical signs of acute respiratory disease with frothy nasal discharge (1-2 days) and mortality of twenty animals (80%) within 48 hr. Necropsy of dead Chowsingha showed haemorrhagic patches in trachea and severe congestion of lungs and ocular mucosa. There was no characteristic lesion in the intestine...
August 14, 2017: Transboundary and Emerging Diseases
https://www.readbyqxmd.com/read/28804685/percutaneous-dilatational-tracheostomy-through-paramedian-technique-and-lateral-approach-in-a-patient-with-cervical-esophagostomy-a-case-report
#6
Kapil D Soni, Neha Garg, Richa Aggarwal, Ambuj Ambuj
BACKGROUND: Percutaneous dilatational tracheostomy (PDT) is a common surgical procedure and established as first choice for securing the airway in critically ill patients needing prolonged mechanical ventilation. There are case reports of open tracheostomy through paramedian approach without complications. This case report presents a case of PDT through paramedian approach. CASE REPORT: An 18 year old female, case of firearm injury underwent cervical esophagostomy on the left side of neck approaching midline...
2017: International Journal of Burns and Trauma
https://www.readbyqxmd.com/read/28801512/unresectable-squamous-cell-carcinoma-of-upper-trachea-with-long-term-survival-after-concurrent-chemoradiotherapy
#7
Prahlad H Yathiraj, Sandeep Ail, Anshul Singh, Vidyasagar Mamidipudi
Upper tracheal malignancies are rare, and long-term survival is even rarer, especially among the unresectable malignancies. A 66-year-old chronic smoker was diagnosed as a locally advanced, non-metastatic squamous cell carcinoma of the upper trachea. Being unresectable, he was treated with six cycles of concurrent weekly cisplatin and three-dimensional conformal radiotherapy to a dose of 60 Gy in 30 fractions over 6 weeks. Follow-up imaging at 6 and 12 months revealed no disease. Our patient is presently 36 months post-treatment and is disease free without tracheal necrosis, fistula or radiation pneumonitis but developed hypothyroidism and is presently euthyroid...
August 11, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28800992/new-approaches-to-airway-management-in-tracheal-resections-a-systematic-review-and-meta-analysis
#8
Mark Schieren, Andreas Böhmer, Fabian Dusse, Aris Koryllos, Frank Wappler, Jerome Defosse
OBJECTIVES: Although endotracheal intubation, surgical crossfield intubation, and jet ventilation are standard techniques for airway management in tracheal resections, there are also reports of new approaches, ranging from regional anesthesia to extracorporeal support. The objective was to outline the entire spectrum of new airway techniques. DESIGN: The literature databases PubMed/Medline and the Cochrane Library were searched systematically for prospective and retrospective trials as well as case reports on tracheal resections...
August 2017: Journal of Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/28796800/the-temporal-dynamics-of-the-tracheal-microbiome-in-tracheostomised-patients-with-and-without-lower-respiratory-infections
#9
Marcos Pérez-Losada, Robert J Graham, Madeline Coquillette, Amenah Jafarey, Eduardo Castro-Nallar, Manuel Aira, Robert J Freishtat, Jonathan M Mansbach
BACKGROUND: Airway microbiota dynamics during lower respiratory infection (LRI) are still poorly understood due, in part, to insufficient longitudinal studies and lack of uncontaminated lower airways samples. Furthermore, the similarity between upper and lower airway microbiomes is still under debate. Here we compare the diversity and temporal dynamics of microbiotas directly sampled from the trachea via tracheostomy in patients with (YLRI) and without (NLRI) lower respiratory infections...
2017: PloS One
https://www.readbyqxmd.com/read/28789874/genotyping-of-avian-infectious-bronchitis-viruses-in-iran-2015-2017-reveals-domination-of-is-1494-like-virus
#10
Amir Modiri, Arash GhalyanchiLangerodui, Masoud Hashemzadeh, Hossein Hosseini, Vahid Karimi, Ramak Yahyaraeyat, Hamideh Najafi
Avian infectious bronchitis virus (IBV) is causing major economic losses to the poultry industry. The analysis of the S1 gene has been used to determine IBV genotype. The aim of this study was genotyping of IBVs circulating among the Iranian broiler flocks in the period between 2015 to 2017. Trachea samples from 278 broiler flocks were collected from broiler farms in eight provinces of Iran. After Real-time RT-PCR, IBV-positive samples were further characterized based on S1 gene. The results of the Real-time RT-PCR showed that 52...
August 5, 2017: Virus Research
https://www.readbyqxmd.com/read/28782137/interkinetic-nuclear-migration-in-the-tracheal-and-esophageal-epithelia-of-the-mouse-embryo-possible-implications-for-tracheo-esophageal-anomalies
#11
Ryo Kaneda, Yuko Saeki, Dereje Getachew, Akihiro Matsumoto, Motohide Furuya, Noriko Ogawa, Tomoyuki Motoya, Ashiq Mahmood Rafiq, Esrat Jahan, Jun Udagawa, Ryuju Hashimoto, Hiroki Otani
Interkinetic nuclear migration (INM) is a cell polarity-based phenomenon in which progenitor cell nuclei migrate along the apico-basal axis of the pseudostratified epithelium in synchrony with the cell cycle. INM is suggested to be at least partially cytoskeleton-dependent and to regulate not only the proliferation/differentiation of stem/progenitor cells but also the localized/overall size and shape of organs/tissues. INM occurs in all three of the germ-layer derived epithelia, including the endoderm-derived gut...
August 6, 2017: Congenital Anomalies
https://www.readbyqxmd.com/read/28780837/-application-and-efficacy-of-endotracheal-tube-of-drug-injection-for-postoperative-patients
#12
S Q Liu, Z Liu, W C Yang, Z H Hu, J L Zhang, Y Li
Objective: To evaluate the efficacy of endotracheal tube for drug injection in postoperative ICU patients. Methods: A total of 60 ICU patients who were given mechanical ventilation after surgical treatment were enrolled in this study from January 2015 to August 2016 at our hospital. All the patients were divided into the observation group (30 cases) and the control group (30 cases). In the observation group, the patients were treated with the endotracheal tube for surface anesthesia by injecting 2% lidocaine into the trachea, and patients in the control group were treated with saline instead of lidocaine...
August 1, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28776693/a-comparison-of-tracheal-scaffold-strategies-for-pediatric-transplantation-in-a-rabbit-model
#13
Elizabeth F Maughan, Colin R Butler, Claire Crowley, Gui Zhen Teoh, Margot Den Hondt, Nicholas J Hamilton, Robert E Hynds, Peggy Lange, Tahera Ansari, Luca Urbani, Samuel M Janes, Paolo De Coppi, Martin A Birchall, Martin J Elliott
OBJECTIVES/HYPOTHESIS: Despite surgical advances, childhood tracheal stenosis is associated with high morbidity and mortality. Various tracheal scaffold strategies have been developed as the basis for bioengineered substitutes, but there is no consensus on which may be superior in vivo. We hypothesized that there would be no difference in morbidity and mortality between three competing scaffold strategies in rabbits. STUDY DESIGN: Pilot preclinical study. METHODS: Tracheal scaffolds were prepared by three methods that have been applied clinically and reported: preserved cadaveric ("Herberhold") allografts, detergent-enzymatically decellularized allografts, and synthetic scaffolds (nanocomposite polymer [polyhedral oligomeric silsesquioxane poly(carbonate-urea) urethane (POSS-PCU)])...
August 4, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28774673/can-videolaryngoscopy-be-a-first-option-in-a-patient-with-laryngeal-amyloidosis
#14
L España Fuente, G Mella Pérez, B Laserna Cocina, J L González González
Amyloidosis is a term that involves a group of diseases characterised by deposition of extracellular monoclonal light-chain fibrillar immunoglobulin aggregates in the body, including many organs, with the larynx among them. A case is presented of a 78 year-old man who was referred to our institution for strangulated umbilical hernia treatment. He suffered from progressive hoarseness and dysphagia for 5months. He had a history of primary laryngeal amyloidosis. Awake intubation was performed successful with the King Vision(®) video-laryngoscopy...
July 31, 2017: Revista Española de Anestesiología y Reanimación
https://www.readbyqxmd.com/read/28774013/additive-manufacturing-of-patient-customizable-scaffolds-for-tubular-tissues-using-the-melt-drawing-method
#15
Yu Jun Tan, Xipeng Tan, Wai Yee Yeong, Shu Beng Tor
Polymeric fibrous scaffolds for guiding cell growth are designed to be potentially used for the tissue engineering (TE) of tubular organs including esophagi, blood vessels, tracheas, etc. Tubular scaffolds were fabricated via melt-drawing of highly elastic poly(l-lactide-co-ε-caprolactone) (PLC) fibers layer-by-layer on a cylindrical mandrel. The diameter and length of the scaffolds are customizable via 3D printing of the mandrel. Thickness of the scaffolds was varied by changing the number of layers of the melt-drawing process...
November 3, 2016: Materials
https://www.readbyqxmd.com/read/28771438/fetal-goitrous-hypothyroidism-treated-by-intra-amniotic-levothyroxine-administration-case-report-and-review-of-the-literature
#16
Mami Kobayashi, Hideaki Yagasaki, Tomohiro Saito, Atsushi Nemoto, Atsushi Naito, Kanji Sugita
BACKGROUND: Fetal goitrous hypothyroidism is mainly caused by maternal treatment of Graves' disease. Fetal goiter sometimes compresses the trachea and esophagus and may cause polyhydramnios, preterm labor, complications of labor and delivery, and neonatal respiratory disorder. CASE PRESENTATION: We report a case of fetal goitrous hypothyroidism in which the mother had Graves' disease, which was treated with propylthiouracil. Intra-amniotic levothyroxine (L-T4) administration was performed, and the fetal goiter decreased in size...
August 3, 2017: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/28770245/molecular-characterization-and-phylogenetic-analyses-of-virulent-infectious-bronchitis-viruses-isolated-from-chickens-in-eastern-saudi-arabia
#17
Maged Gomaa Hemida, Mohammed A Al-Hammadi, Abdul Hafeed S Daleb, Cecilio R Gonsalves
Infectious bronchitis virus (IBV) is one of the major respiratory viral threats for chickens. Despite the intensive application of IBV vaccines, several outbreaks have been reported worldwide. Here, we report several IBV outbreaks in thirteen poultry farms in Eastern Saudi Arabia (ESA) from 2013 to 2014. The main goals of the current study were as follows: (1) isolation and molecular characterization of the currently circulating strains in ESA (Al-Hasa, Dammam, and Buqayq) and (2) evaluation of the immune status of these birds to IBV...
June 2017: Virusdisease
https://www.readbyqxmd.com/read/28767607/primary-clear-cell-carcinoma-of-the-trachea-a-care-compliant-case-report
#18
Min Li, Wenye Zhu, Rana Sami Ullah Khan, Ummair Saeed, Shaoqing Shi, Zhuang Luo
RATIONALE: Primary clear cell carcinoma of the lung is a rare condition, and presentation as an endotracheal lesion is even more unusual. In this report, we present a patient with clear cell carcinoma occurring in the trachea, which obstructed the tracheal lumen and lead to the respiratory distress. PATIENT CONCERNS: A 60-year old female patient was admitted due to a 6-month history of dyspnea with worsening symptoms for 1 month. Chest CT scan revealed a smooth nodular shadow with homogeneous density on the wall of upper trachea...
August 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28763472/infectious-bronchitis%C3%A2-corona%C3%A2-virus%C3%A2-establishes-productive-infection-in-avian-macrophages-interfering-with-selected-antimicrobial-functions
#19
Aruna Amarasinghe, Mohamed Sarjoon Abdul-Cader, Sadiya Nazir, Upasama De Silva Senapathi, Frank van der Meer, Susan Catherine Cork, Susantha Gomis, Mohamed Faizal Abdul-Careem
Infectious bronchitis virus (IBV) causes respiratory disease leading to loss of egg and meat production in chickens. Although it is known that macrophage numbers are elevated in the respiratory tract of IBV infected chickens, the role played by macrophages in IBV infection, particularly as a target cell for viral replication, is unknown. In this study, first, we investigated the ability of IBV to establish productive replication in macrophages in lungs and trachea in vivo and in macrophage cell cultures in vitro using two pathogenic IBV strains...
2017: PloS One
https://www.readbyqxmd.com/read/28758273/assessment-of-computed-tomography-derived-cricoid-cartilage-and-tracheal-dimensions-to-evaluate-degree-of-cricoid-narrowing-in-brachycephalic-dogs
#20
Lynda Rutherford, Lee Beever, Mieghan Bruce, Gert Ter Haar
The aims of this observational, analytical, retrospective study were to (i) obtain computed tomographic (CT) cricoid dimensions (height, width, and transverse-sectional area), (ii) compare the cricoid dimensions between brachycephalic and mesaticephalic breeds, and (iii) compare cricoid cartilage dimensions between dogs without and affected with brachycephalic airway syndrome. The study is important to help to further evaluate and understand the anatomical components of brachycephalic airway syndrome. Measurements were performed in 147 brachycephalic and 59 mesaticephalic dogs...
July 30, 2017: Veterinary Radiology & Ultrasound
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