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https://www.readbyqxmd.com/read/28327162/biological-effects-of-carbon-black-nanoparticles-are-changed-by-surface-coating-with-polycyclic-aromatic-hydrocarbons
#1
Karina Lindner, Michael Ströbele, Sandra Schlick, Sina Webering, André Jenckel, Johannes Kopf, Olga Danov, Katherina Sewald, Christian Buj, Otto Creutzenberg, Thomas Tillmann, Gerhard Pohlmann, Heinrich Ernst, Christina Ziemann, Gereon Hüttmann, Holger Heine, Henning Bockhorn, Tanja Hansen, Peter König, Heinz Fehrenbach
BACKGROUND: Carbon black nanoparticles (CBNP) are mainly composed of carbon, with a small amount of other elements (including hydrogen and oxygen). The toxicity of CBNP has been attributed to their large surface area, and through adsorbing intrinsically toxic substances, such as polycyclic aromatic hydrocarbons (PAH). It is not clear whether a PAH surface coating changes the toxicological properties of CBNP by influencing their physicochemical properties, through the specific toxicity of the surface-bound PAH, or by a combination of both...
March 21, 2017: Particle and Fibre Toxicology
https://www.readbyqxmd.com/read/28325777/intratracheal-seal-disc-a-novel-tracheostoma-closure-device
#2
Karen J Christiansen, Niels Moeslund, Henrik Lauridsen, Louise Devantier, Marianne C Rohde, Benedict Kjœrgaard, Michael Pedersen
BACKGROUND: Tracheostomy decannulation is accompanied by several clinical concerns due to air leakage. In this study, we introduced a novel tracheostoma closure device that facilitates the use of noninvasive ventilation, improvement of pulmonary function, and vocalization in the newly decannulated patient. The biosafety and feasibility of the device were evaluated in an animal model. METHODS: Five Danish Landrace pigs were subjected to tracheostomy followed by decannulation and insertion of the tracheostoma closure device...
March 21, 2017: Respiratory Care
https://www.readbyqxmd.com/read/28323575/lung-laryngeal-and-other-respiratory-cancer-incidence-among-japanese-atomic-bomb-survivors-an-updated-analysis-from-1958-through-2009
#3
Elizabeth K Cahoon, Dale L Preston, Donald A Pierce, Eric Grant, Alina V Brenner, Kiyohiko Mabuchi, Mai Utada, Kotaro Ozasa
The Life Span Study (LSS) of Japanese atomic bomb survivors is comprised of a large, population-based cohort offering one of the best opportunities to study the relationship between exposure to radiation and incidence of respiratory cancers. Risks of lung, laryngeal and other cancers of the respiratory system were evaluated among 105,444 LSS subjects followed from 1958 to 2009. During this period, we identified 2,446 lung, 180 laryngeal and 115 other respiratory (trachea, mediastinum and other ill-defined sites) first primary incident cancer cases...
March 21, 2017: Radiation Research
https://www.readbyqxmd.com/read/28320373/nelumbo-nucifera-leaves-extracts-inhibit-mouse-airway-smooth-muscle-contraction
#4
Xiao Yang, Lu Xue, Qingyang Zhao, Congli Cai, Qing-Hua Liu, Jinhua Shen
BACKGROUND: Alkaloids extracted from lotus leaves (AELL) can relax vascular smooth muscle. However, whether AELL has a similar relaxant role on airway smooth muscle (ASM) remains unknown. This study aimed to explore the relaxant property of AELL on ASM and the underlying mechanism. METHODS: Alkaloids were extracted from dried lotus leaves using the high temperature rotary evaporation extraction method. The effects of AELL on mouse ASM tension were studied using force measuring and patch-clamp techniques...
March 20, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28316928/double-aortic-arch-diagnosed-in-a-44-year-old-woman-with-recurring-respiratory-infections
#5
Ana Fenández-Tena, Cristina Martínez-González
Complete vascular rings are originated because of the persistence of the fourth aortic arches, which surround the trachea and esophagus partially or completely, compressing them. The most common type of complete vascular ring is the double aortic arch. Symptoms usually appear in the first months of life, and are provoked by esophageal and tracheal compression. The diagnosis is usually made through the chest X-ray and the esophagogram in patients with dysphagia. We present a case in which the diagnosis of a double aortic arch was made in adulthood, suspected through a spirometry test and a chest X-ray...
2017: Respiratory Medicine Case Reports
https://www.readbyqxmd.com/read/28314172/the-risk-of-cancer-in-the-offspring-and-parental-length-of-life
#6
Ruby Del Risco Kollerud, Karl Gerhard Blaasaas, Bjørgulf Claussen, Bente Oftedal, Øyvind Næss
BACKGROUND: We investigated if cancer onset in offspring is related to having short-lived parents for different cancer types and to see if there was a difference in smoking- and non-smoking related cancers. METHODS: Our study included 524,391 individuals born in Norway 1940-1950. All children were followed up for cancer from the age of 20 until they were between 59 and 69 years. Parental longevity was examined by grouping parental age of death into parents dying before 75 years of age and parents dying at 75 years of age or older...
March 14, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28302227/anaesthetic-concerns-of-surgical-emphysema-following-thyroidectomy
#7
Sanum Kashif, Amna Gulrez
Surgical emphysema secondary to tracheal tear is a rare but serious complication after thyroidectomy. It is usually resolved by conservative management; but in case of compromised airway, early airway control and surgical intervention is required. This is the case report of a 52-year woman diagnosed as thyroid carcinoma, who developed rapidly progressive surgical emphysema involving head and upper thorax, following total thyroidectomy, in post anesthesia care unit (PACU). The complication was related to tracheal tear occurring during excision of huge thyroid mass, encroaching trachea...
March 2017: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/28301367/reconstruction-of-a-long-segment-tracheal-defect-using-an-alloderm-conduit
#8
William D Bolton, Sharon Ben-Or, Allyson L Hale, James E Stephenson
This case describes successful reconstruction of a long-segment tracheal defect using AlloDerm as the conduit for reconstruction. A 38-year-old woman who had undergone a thyroid lobectomy in 2011 presented several months later unable to swallow. Chest computed tomography results revealed a tracheal/esophageal mass and a subsequent bronchoscopy, and esophagogastroduodenoscopy results revealed an upper esophageal/tracheal mass with two areas concerning for fistula. She underwent a bronchoscopy with a tracheal stent and percutaneous endoscopic gastrostomy placement...
March 15, 2017: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
https://www.readbyqxmd.com/read/28301245/prevalence-of-taxa-of-pasteurellaceae-among-populations-of-healthy-captive-psittacine-birds
#9
M Bisgaard, Di Xin, M F Bertelsen, A M Bojesen, H Christensen
Sixty-two strains of Pasteurellaceae-like bacteria were isolated from the tracheas of 87 clinically healthy psittacine birds in two Danish zoos. The isolates were identified by a combination of rpoB and 16S rRNA gene sequencing and by matrix-assisted laser desorption-ionization time of flight. Twenty-eight strains belonged to the genus Volucribacter or were related to this genus and to the unnamed taxon 34 of Bisgaard, and 28 strains were related to the unnamed taxon 44 of Bisgaard. Four strains were identified as Pasteurella multocida , two isolates were classified with the related taxon 45 of Bisgaard, and a single isolate was classified as Pasteurella sp...
March 2017: Avian Diseases
https://www.readbyqxmd.com/read/28298795/a-novel-and-innovative-way-of-nasogastric-tube-insertion-in-anesthetized-intubated-patient
#10
Sandeep Sahu, Kamal Kishore, Vertika Sachan, Arnidam Chatterjee
Nasogastric tube (NGT) placement in anesthetized and intubated is sometimes very challenging with more than 50% failure rate in the first attempt. We describe a newer innovative Sahu's three in one, technique with use of GlideScope and forward placement of intubated trachea by external laryngeal maneuver, these both techniques lead to separation of trachea from esophagus so that endoscopic jejunal feeding tube guide wire strengthen NGT can be guided and manipulated to esophagus under direct vision. After informed consent, we used Sahu's three in one combo technique to insert NGT in adult anesthetized and intubated patients of both the sexes with high success in the first attempt...
January 2017: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/28298739/plasmacytoma-of-the-trachea-a-surprising-diagnosis
#11
Márcio Luís Duarte, Mariana Carneiro Barbosa de Brito, Fabricius André Lyrio Traple, José Luiz Masson de Almeida Prado, Luiz Carlos Donoso Scoppetta
No abstract text is available yet for this article.
January 2017: Radiologia Brasileira
https://www.readbyqxmd.com/read/28298611/frequency-tuning-and-directional-sensitivity-of-tympanal-vibrations-in-the-field-cricket-gryllus-bimaculatus
#12
Martin J Lankheet, Uroš Cerkvenik, Ole N Larsen, Johan L van Leeuwen
Female field crickets use phonotaxis to locate males by their calling song. Male song production and female behavioural sensitivity form a pair of matched frequency filters, which in Gryllus bimaculatus are tuned to a frequency of about 4.7 kHz. Directional sensitivity is supported by an elaborate system of acoustic tracheae, which make the ears function as pressure difference receivers. As a result, phase differences between left and right sound inputs are transformed into vibration amplitude differences. Here we critically tested the hypothesis that acoustic properties of internal transmissions play a major role in tuning directional sensitivity to the calling song frequency, by measuring tympanal vibrations as a function of sound direction and frequency...
March 2017: Journal of the Royal Society, Interface
https://www.readbyqxmd.com/read/28298440/structural-basis-of-outer-dynein-arm-intraflagellar-transport-by-the-transport-adaptor-protein-oda16-and-the-intraflagellar-transport-protein-ift46
#13
Michael Taschner, André Mourão, Mayanka Awasthi, Jerome Basquin, Esben Lorentzen
Motile cilia are found on unicellular organisms such as the green alga Chlamydomonas reinhardtii, on sperm cells, and on cells that line the trachea and fallopian tubes in mammals. The motility of cilia relies on a number of large protein complexes including the force-generating outer dynein arms (ODAs). The transport of ODAs into cilia has been previously shown to require the transport adaptor ODA16 as well as the intraflagellar transport (IFT) protein IFT46, but the molecular mechanism by which ODAs are recognized and transported into motile cilia is still unclear...
March 15, 2017: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/28296730/image-quality-evaluation-for-care-kv-technique-combined-with-iterative-reconstruction-for-chest-computed-tomography-scanning
#14
Bin Yang, Zheng-Liang Li, Yi Gao, Ya-Ying Yang, Wei Zhao
BACKGROUND: To investigate the radiation dose and image quality for iterative reconstruction combined with the CARE kV technique in chest computed tomography (CT) scanning for physical examination. METHODS: A total of 130 patients who underwent chest CT scanning were randomly chosen and the quality reference value was set as 80 mAs. The scanning scheme was set and the patients were randomly divided into groups according to the scanning scheme. Sixty patients underwent a chest scan with 100 kV using the CARE kV technique and SAFIRE reconstruction (value=3) (experimental group) and the other 70 patients underwent chest scanning with 120 kV (control group)...
March 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28295658/successful-closure-of-post-tracheostomy-large-chronic-trachea-esophageal-fistula-with-new-over-the-scope-clip
#15
P Rai, R Bhargava
Acquired tracheo-esophageal fistula mostly occurs secondary to malignancy, infection, ruptured diverticula, and injuries.(1) Among the benign conditions, prolonged mechanical ventilation is the most common (47%), followed by injury (17%), prior laryngectomy (17%), and prior esophagostomy (17%).(2) A 19 y male had a road traffic accident and was managed in an intensive care unit with ventilator support and had tracheostomy for 20 days. This article is protected by copyright. All rights reserved.
March 10, 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/28294161/in-vivo-imaging-of-the-muc5b-gel-forming-mucin
#16
Céline Portal, Valérie Gouyer, Mylène Magnien, Ségolène Plet, Frédéric Gottrand, Jean-Luc Desseyn
Gel-forming mucins are macromolecules produced by goblet cells and responsible for the mucus gel formation. Changes in goblet cell density and in gel-forming mucin production have emerged as sensitive indicators for mucosal diseases. A Muc5b-GFP tagged reporter mouse was used to assess Muc5b production in mouse tissues by immunofluorescence microscopy and fluorescent activity using stereromicroscopy and probe-based confocal laser endomicroscopy. Muc5b production was followed longitudinally by recording the fluorescent activity in vagina and in embryonic lung explants under stimulation by interleukin 13...
March 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28293872/effect-of-high-laser-output-on-the-central-bronchi-and-pulmonary-artery
#17
A Kirschbaum, P Rexin, D K Bartsch, K Quint
A diode-pump Nd:YAG high-power laser (wavelength 1320 nm, power 100 W) is routinely used to surgically remove lung metastases. Even pulmonary lesions in central locations are resectable via this method, yet it also carries a potential risk of damaging the larger bronchi and vessels in the vicinity. Studies investigating the safety of using high-power lasers are lacking. We therefore aimed to examine the direct effects of a 100-watt laser on the bronchi and pulmonary artery at a standard working velocity. From freshly slaughtered pigs, we isolated cylindrical specimens of the trachea, the main and lobar bronchi, and the central pulmonary artery from the both lungs...
March 14, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28292511/thoracic-stomach-right-main-bronchus-fistula-treated-with-dual-y-shaped-covered-airway-stents
#18
Z-M Li, H-B Lu, K-W Ren, X-W Han, G Wu, D-C Jiao
AIM: To determine the efficacy of dual Y-shaped covered airway stents to treat thoracic stomach-right main bronchus fistulae. MATERIAL AND METHODS: Fifteen patients who developed thoracic stomach-right main bronchus fistula after oesophageal cancer resection and postoperative irradiation were retrospectively analysed. All fistulae were close to the right upper lobe bronchus. Two Y-shaped covered airway stents were designed for each patient. Under radiographic guidance, one stent was placed from the right main bronchus into the bifurcation of upper lobe and intermediate bronchus, the other was placed from the trachea into both main bronchi...
March 11, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/28291400/effect-of-variations-in-stent-placement-on-outcome-of-endoluminal-stenting-for-canine-tracheal-collapse
#19
Stephanie Rosenheck, Garrett Davis, Carl D Sammarco, Richard Bastian
The study's objective was to determine effects of relative size and placement location of endoluminal stents on incidence of complications and survival for canine tracheal collapse. Measurements were obtained on lateral radiographs before and after stenting to determine percent of the trachea occupied by the stent. These values were monitored over time and compared to complication rates and survival. Overall median survival time was 502 days. Six month survival rate was 78%, 1 yr survival was 60%, and 2 yr survival was 26%...
March 14, 2017: Journal of the American Animal Hospital Association
https://www.readbyqxmd.com/read/28290239/an-innovative-design-for-cardiopulmonary-resuscitation-manikins-based-on-a-human-like-thorax-and-embedded-flow-sensors
#20
Mark Thielen, Rohan Joshi, Frank Delbressine, Sidarto Bambang Oetomo, Loe Feijs
Cardiopulmonary resuscitation manikins are used for training personnel in performing cardiopulmonary resuscitation. State-of-the-art cardiopulmonary resuscitation manikins are still anatomically and physiologically low-fidelity designs. The aim of this research was to design a manikin that offers high anatomical and physiological fidelity and has a cardiac and respiratory system along with integrated flow sensors to monitor cardiac output and air displacement in response to cardiopulmonary resuscitation. This manikin was designed in accordance with anatomical dimensions using a polyoxymethylene rib cage connected to a vertebral column from an anatomical female model...
March 2017: Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine
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