keyword
MENU ▼
Read by QxMD icon Read
search

treponema

keyword
https://www.readbyqxmd.com/read/29341338/human-teeth-biobank-microbiological-analysis-of-the-teeth-storage-solution
#1
Fabiana Almeida Curylofo-Zotti, Francine Lorencetti-Silva, Jéssica de Almeida Coelho, Rachel Maciel Monteiro, Evandro Watanabe, Silmara Aparecida Milori Corona
The cross-infections may occur during handling of dental elements, affecting the health of dental practitioners and researchers. This study aimed to analyze the influence of the storage medium temperature on the bacterial contingent of the human teeth used for research purposes. Thirty human teeth were donated to the Human Teeth Biobank immediately after extraction. The teeth were cleaned with tap water and neutral soap. The teeth were randomly distributed according to the temperature of the storage solution (deionized water): at 4 °C (refrigerator) or at -10 °C (freezer) and were stored individually in sterile vials during 60 days...
January 17, 2018: Microscopy Research and Technique
https://www.readbyqxmd.com/read/29333776/-clinical-and-microbiologic-follow-up-evaluations-after-non-surgical-periodontal-treatment-with-nd-yag-laser-and-scaling-and-root-planning
#2
Yin Yanli, Xu Chunmei, Wu Yafei, Zhao Lei
OBJECTIVE: Our research aimed to detect the efficacy of non-surgical periodontal treatment with Nd: YAG laser and scaling and root planning (SRP) for chronic periodontitis. METHODS: We recruited chronic periodontitis patients who have more than four teeth with clinical pocket depth of 4-8 mm. These teeth were distributed in four different zones within the oral cavity. Moreover, the teeth were single root teeth and not adjacent to each other. The subordinated teeth were randomized into four groups, as follows: no treatment (C group), simple SRP (SRP group), Nd: YAG laser after SRP treatment (SRP+L group), and SRP after Nd: YAG laser treatment (L+SRP group)...
December 1, 2017: Hua Xi Kou Qiang Yi Xue za Zhi, Huaxi Kouqiang Yixue Zazhi, West China Journal of Stomatology
https://www.readbyqxmd.com/read/29330119/temporal-changes-of-the-bacterial-community-colonizing-wheat-straw-in-the-cow-rumen
#3
Wei Jin, Ying Wang, Yuanfei Li, Yanfen Cheng, Weiyun Zhu
This study used Miseq pyrosequencing and scanning electron microscopy to investigate the temporal changes in the bacterial community tightly attached to wheat straw in the cow rumen. The wheat straw was incubated in the rumens and samples were recovered at various times. The wheat straw degradation exhibited three phases: the first degradation phase occurred within 0.5 h, and the second degradation phase occurred after 6 h, with a stalling phase occurring between 0.5 and 6 h. Scanning electron microscopy revealed the colonization of the microorganisms on the wheat straw over time...
January 9, 2018: Anaerobe
https://www.readbyqxmd.com/read/29327500/multiplex-polymerase-chain-reaction-detection-of-selected-bacterial-species-from-symptomatic-and-asymptomatic-non-vital-teeth-with-primary-endodontic-infections
#4
Smita Pattanshetty, Vijayalakshmi S Kotrashetti, Kishore Bhat, Ramakant S Nayak, Pradeep Somannavar, Madhu Pujar
AIM: The aim of the present study was to investigate the presence of selective anaerobic microorganisms in primary root canal infections of symptomatic and asymptomatic non-vital teeth with periapical pathosis using multiplex polymerase chain reaction. METHODS: A total of 100 root canal samples (50 from symptomatic and 50 from asymptomatic teeth) were obtained from patients with primary endodontic infections. DNA extracted from the samples was amplified by using specific primers for the 16S rRNA gene of each bacterium, and semiquantification was done to analyze the prevalence of microorganisms and their correlation to clinical features...
January 11, 2018: Journal of Investigative and Clinical Dentistry
https://www.readbyqxmd.com/read/29327449/clinical-microbiological-and-cytomorphometric-evaluation-of-low-level-laser-therapy-as-an-adjunct-to-periodontal-therapy-in-patients-with-chronic-periodontitis
#5
M S Petrović, I Y Kannosh, J M Milašin, D S Mihailović, R R Obradović, S R Bubanj, L G Kesić
OBJECTIVE: A clinical prospective study was designed to evaluate microbiological, cytomorphometric and clinical efficacy of low-level laser therapy (LLLT) as an adjunct to periodontal therapy in the treatment of chronic periodontitis. METHODS: Sixty subjects were included and randomly assigned into 2 groups: SRP (scaling root planning) group (n = 30) and LLLT + SRP group (n = 30). Clinical parameters were measured before intervention, after the fifth treatment, and after a month...
January 12, 2018: International Journal of Dental Hygiene
https://www.readbyqxmd.com/read/29325576/reanalysis-of-chinese-treponema-pallidum-samples-all-chinese-samples-cluster-with-ss14-like-group-of-syphilis-causing-treponemes
#6
Michal Strouhal, Jan Oppelt, Lenka Mikalová, Natasha Arora, Kay Nieselt, Fernando González-Candelas, David Šmajs
OBJECTIVE: Treponema pallidum subsp. pallidum (TPA) is the causative agent of syphilis. Genetic analyses of TPA reference strains and human clinical isolates have revealed two genetically distinct groups of syphilis-causing treponemes, called Nichols-like and SS14-like groups. So far, no genetic intermediates, i.e. strains containing a mixed pattern of Nichols-like and SS14-like genomic sequences, have been identified. Recently, Sun et al. (Oncotarget 2016. https://doi.org/10.18632/oncotarget...
January 11, 2018: BMC Research Notes
https://www.readbyqxmd.com/read/29318719/crystal-structures-of-mglb-2-tp0684-a-topologically-variant-d-glucose-binding-protein-from-treponema-pallidum-reveal-a-ligand-induced-conformational-change
#7
Chad A Brautigam, Ranjit K Deka, Wei Z Liu, Michael V Norgard
Previously, we determined the crystal structure of apo-TpMglB-2, a D-glucose-binding component of a putative ABC transporter from the syphilis spirochete Treponema pallidum. The protein had an unusual topology for this class of proteins, raising the question of whether the D-glucose-binding mode would be different in TpMglB-2. Here, we present the crystal structures of a variant of TpMglB-2 with and without D-glucose bound. The structures demonstrate that, despite its aberrant topology, the protein undergoes conformational changes and binds D-glucose similarly to other Mgl-type proteins, likely facilitating D-glucose uptake in T...
January 10, 2018: Protein Science: a Publication of the Protein Society
https://www.readbyqxmd.com/read/29309603/a-non-human-primate-model-for-rectally-transmitted-syphilis
#8
Cassandra Tansey, Chunxia Zhao, Andre Hopkins, Jana M Ritter, Yetunde F Fakile, Allan Pillay, Samantha S Katz, Lara Pereira, James Mitchell, Frank Deyounks, Ellen N Kersh, Janet M McNicholl, Sundaram Ajay Vishwanathan
Men, diagnosed with syphilis or other rectal sexually transmitted infections (STIs), who have sex with men (MSM) are at a higher risk for HIV acquisition, which is concerning given the large increase in recently reported syphilis cases in the United States. We have developed the first non-human primate model for rectally transmitted syphilis by exposing SHIV-infected and naïve rhesus macaques to Treponema pallidum in the rectum. All animals showed mucosal lesions, systemic dissemination, and seroconversion (treponemal antibodies)...
December 22, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29304083/combined-evaluation-of-sexually-transmitted-infections-in-hiv-infected-pregnant-women-and-infant-hiv-transmission
#9
Kristina Adachi, Jiahong Xu, Nava Yeganeh, Margaret Camarca, Mariza G Morgado, D Heather Watts, Lynne M Mofenson, Valdilea G Veloso, Jose Henrique Pilotto, Esau Joao, Glenda Gray, Gerhard Theron, Breno Santos, Rosana Fonseca, Regis Kreitchmann, Jorge Pinto, Marisa M Mussi-Pinhata, Mariana Ceriotto, Daisy Maria Machado, Yvonne J Bryson, Beatriz Grinsztejn, Jack Moye, Jeffrey D Klausner, Claire C Bristow, Ruth Dickover, Mark Mirochnick, Karin Nielsen-Saines
BACKGROUND: Sexually transmitted infections (STIs) including Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG), Treponema pallidum (TP), and cytomegalovirus (CMV) may lead to adverse pregnancy and infant outcomes. The role of combined maternal STIs in HIV mother-to-child transmission (MTCT) was evaluated in mother-infant pairs from NICHD HPTN 040. METHODOLOGY: Urine samples from HIV-infected pregnant women during labor were tested by polymerase chain reaction (PCR) for CT, NG, and CMV...
2018: PloS One
https://www.readbyqxmd.com/read/29281641/development-of-a-multilocus-sequence-typing-mlst-scheme-for-treponema-pallidum-subsp-pertenue-application-to-yaws-in-lihir-island-papua-new-guinea
#10
Charmie Godornes, Lorenzo Giacani, Alyssa E Barry, Oriol Mitja, Sheila A Lukehart
BACKGROUND: Yaws is a neglected tropical disease, caused by Treponema pallidum subsp. pertenue. The disease causes chronic lesions, primarily in young children living in remote villages in tropical climates. As part of a global yaws eradication campaign initiated by the World Health Organization, we sought to develop and evaluate a molecular typing method to distinguish different strains of T. pallidum subsp. pertenue for disease control and epidemiological purposes. METHODS AND PRINCIPAL FINDINGS: Published genome sequences of strains of T...
December 27, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29277436/-the-key-role-of-the-pathologist-in-the-diagnosis-of-syphilis-a-case-report
#11
Cécile Picard, Juliette Fontaine, Brigitte Chouvet, Brigitte Balme, Alexandra Traverse-Glehen
Syphilis is a resurging sexually transmitted infection linked to Treponema Pallidum. Syphilitic lymphadenitis can be present during the 3 stages of the disease. Its histological diagnosis remains challenging for the pathologist given its possible misleading aspect and its ability to mimic as well as reactional as tumoral conditions. We report the case of an HIV-infected young patient referred for suspicion of an aggressive lymphoma. Histological and immunohistochemical analysis of cervical lymphadenopathy revealed secondary syphilis...
December 22, 2017: Annales de Pathologie
https://www.readbyqxmd.com/read/29240636/the-etiology-of-genital-ulcer-disease-and-coinfections-with-chlamydia-trachomatis-and-neisseria-gonorrhoeae-in-zimbabwe-results-from-the-zimbabwe-sti-etiology-study
#12
More Mungati, Anna Machiha, Owen Mugurungi, Mufuta Tshimanga, Peter H Kilmarx, Justice Nyakura, Gerald Shambira, Vitalis Kupara, David A Lewis, Elizabeth Gonese, Beth A Tippett Barr, H Hunter Handsfield, Cornelis A Rietmeijer
BACKGROUND: In many countries, sexually transmitted infections (STIs) are treated syndromically. Thus, patients diagnosed as having genital ulcer disease (GUD) in Zimbabwe receive a combination of antimicrobials to treat syphilis, chancroid, lymphogranuloma venereum (LGV), and genital herpes. Periodic studies are necessary to assess the current etiology of GUD and assure the appropriateness of current treatment guidelines. MATERIALS AND METHODS: We selected 6 geographically diverse clinics in Zimbabwe serving high numbers of STI cases to enroll men and women with STI syndromes, including GUD...
January 2018: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/29236656/secondary-syphilis-associated-with-membranous-nephropathy-and-acute-hepatitis-in-a-patient-with-hiv-a-case-report
#13
Zhou Zhang, Aviv Hever, Nitin Bhasin, Dean A Kujubu
INTRODUCTION: We present a case of membranous nephropathy associated with a secondary syphilis infection in a patient with HIV. CASE PRESENTATION: A 37-year-old white man with HIV who was receiving highly active antiretroviral therapy presented to the Emergency Department with 6 weeks of rectal pain. He had a CD3-CD4 count of 656 cells/mm3 and an undetectable viral load. On admission, he was found to have an anal ulcer, a serum creatinine of 1.4 mg/dL (baseline 0...
2017: Permanente Journal
https://www.readbyqxmd.com/read/29229275/frequency-of-treponema-pallidum-invasion-into-cerebrospinal-fluid-in-primary-or-secondary-early-stage-syphilis
#14
Mao Hagihara, Yuka Yamagishi, Hideo Kato, Yuichi Shibata, Arufumi Shiota, Daisuke Sakanashi, Hiroyuki Suematsu, Hiroki Watanabe, Nobuhiro Asai, Yusuke Koizumi, Tatsuro Furui, Seiichiro Takahashi, Koji Izumi, Hiroshige Mikamo
Frequency of Treponema pallidum invasion into cerebrospinal fluid (CSF) has not been clear at this present. Since it is impossible to culture T. pallidum in vitro at this present, we need molecular based-approach to detect it in CSF. Additionally, neurosyphilis is usually a late sequela, however it might result in asymptomatic neurosyphilis even at primary or secondary syphilis. This study was to reveal the frequency of T. pallidum invasion into CSF especially at primary or secondary syphilis with polymerase chain reaction (PCR) test...
December 8, 2017: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://www.readbyqxmd.com/read/29228176/screening-and-identification-of-immunoactive-flab-protein-fragments-of-treponema-pallidum-for-the-serodiagnosis-of-syphilis
#15
Manyi Tan, Man Xu, Yongjian Xiao, Yafeng Xie, Chuanhao Jiang, Kang Zheng, Qian Chen, Feijun Zhao, Tiebing Zeng, Yimou Wu
Flagellin is a classical pathogen-associated molecular pattern that can evoke robust immune response. We have demonstrated previously that three full-length flagellins of Treponema pallidum, namely FlaB1, FlaB2 and FlaB3, did have diagnostic value in serodiagnosis of syphilis. Here, we selected and constructed three recombinant fragments of each complete FlaB, both the conserved N-terminal and the C-terminal region, and the middle variable part, with the goal of exploring fragment unique to Treponema pallidum for use as antigen target in a fragment based serological test...
December 5, 2017: Pathogens and Disease
https://www.readbyqxmd.com/read/29225977/double-morphology-tertiary-syphilis-and-acquired-immunodeficiency-syndrome-a-rare-association
#16
R M Ngwanya, B Kakande, N P Khumalo
Background: Human immunodeficiency virus (HIV) and Treponema pallidum coinfection is relatively common and accounts for about 25% of primary and secondary syphilis. Tertiary syphilis in HIV-uninfected and HIV-infected patients is vanishingly rare. This is most likely due to early treatment of cases of primary and secondary syphilis. There is rapid progression to tertiary syphilis in HIV-infected patients. Case Presentation: A 49-year-old woman diagnosed with HIV Type 1 infection and cluster of differentiation 4 (CD4) count of 482 presented with a four-week history of multiple crusted plaques, nodules, and ulcers on her face, arms, and abdomen...
2017: Case Reports in Dermatological Medicine
https://www.readbyqxmd.com/read/29224873/a-clinical-and-histopathological-comparison-of-the-effectiveness-of-salicylic-acid-to-a-compound-of-inorganic-acids-for-the-treatment-of-digital-dermatitis-in-cattle
#17
N Capion, E K Larsson, O L Nielsen
Bovine digital dermatitis (DD) is a painful infectious disease, causing lameness, reduced animal welfare, and production losses in dairy herds. The main factors contributing to DD are an infection with Treponema spp. and poor hygiene. Topical treatment has primarily consisted of antibiotics; however, the demand for effective nonantibiotic alternatives is increasing. The objective was to evaluate the performance of 3 nonantibiotic topical treatments (salicylic acid and a compound of inorganic acids in a 20% solution and in a dry form) on DD in a commercial dairy herd...
December 7, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/29223963/field-evaluation-of-two-point-of-care-tests-for-syphilis-among-men-who-have-sex-with-men-verona-italy
#18
Antonella Zorzi, Maddalena Cordioli, Lorenzo Gios, Paola Del Bravo, Igor Toskin, Rosanna W Peeling, Karel Blondeel, Giuseppe Cornaglia, James Kiarie, Ronald Ballard, Massimo Mirandola
OBJECTIVES: The incidence of HIV and syphilis among men who have sex with men (MSM) in Europe has recently increased. Rapid point-of-care tests (POCTs) for syphilis can improve access to screening. The purpose of this study was to evaluate the performance of two syphilis POCTs compared with laboratory tests among MSM. METHODS: The study was undertaken in Verona, Italy. Asymptomatic MSM, potentially exposed to syphilis, were enrolled prospectively. The POCTs evaluated were SD Bioline Syphilis 3...
December 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/29205773/treponema-denticola-increases-mmp-2-expression-and-activation-in-the-periodontium-via-reversible-dna-and-histone-modifications
#19
Islam M Ateia, Pimchanok Sutthiboonyapan, Pachiyappan Kamarajan, Taocong Jin, Valentina Godovikova, Yvonne L Kapila, J Christopher Fenno
Host-derived matrix metalloproteinases (MMPs) and bacterial proteases mediate destruction of extracellular matrices and supporting alveolar bone in periodontitis. The Treponema denticola dentilisin protease induces MMP-2 expression and activation in periodontal ligament (PDL) cells, and dentilisin-mediated activation of pro-MMP-2 is required for cellular fibronectin degradation. Here we report that T. denticola regulates MMP-2 expression through epigenetic modifications in the periodontium. PDL cells were treated with epigenetic enzyme inhibitors before or after T...
December 4, 2017: Cellular Microbiology
https://www.readbyqxmd.com/read/29201173/serological-evaluation-of-antigen-tp0693-for-diagnosis-of-syphilis
#20
Li Zhang, Meixia Deng, Xiaohong Zhang, Weiguo Yin, Wen Liu, Xi Luo, Jie Yang, Fei Chen, Feijun Zhao
The aim of the present study was to evaluate the diagnostic value of the Treponema pallidum (Tp) antigen Tp0693 for syphilis. ELISA was used to examine the serum levels of Tp0693. The sample-to-cutoff ratio (S/CO) value was used to generate a receiver operating characteristic (ROC) curve. A correlation analysis was performed to compare the detection efficacy of Tp0693-specific ELISA, Treponema pallidum Particle Agglutination (TPPA), Tolulized Red Unheated Serum test (TRUST) and LiZhu™ Tp-ELISA. The area under the ROC curve was 0...
November 2017: Experimental and Therapeutic Medicine
keyword
keyword
12229
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"