Wtf

It is vital for the development and application of heavy metal stabilization/solidification (S/S) agents to reveal the mechanism of the reaction between water-soluble thiourea formaldehyde (WTF) resin and heavy metal and evaluate its repairing effect. Based on the density functional theory analysis of the WTF resin structure, the mechanism analysis and scanning electron microscope (SEM) showed that the three-dimensional network structure with thiocarbonyl and hydroxyl groups is very conducive to the capture of Cd2+ ...

Groundwater recharge estimation, aquifer response to meteorological variables, and evapotranspiration calculations have been performed on a semi-humid catchment, in northwestern Ethiopian plateau. The Soil Moisture Balance (SMB), WetSpass water balance model, Water Table Fluctuation (WTF), and Chloride Mass Balance (CMB) methods are applied to estimate the groundwater recharge. Accordingly, 431 mm, 462 mm, and 477 mm recharge amounts are estimated as mean annual value, respectively, using SMB, WetSpass, and CMB methods...

Meiotic drivers are parasitic loci that force their own transmission into greater than half of the offspring of a heterozygote. Many drivers have been identified, but their molecular mechanisms are largely unknown. The wtf4 gene is a meiotic driver in Schizosaccharomyces pombe that uses a poison-antidote mechanism to selectively kill meiotic products (spores) that do not inherit wtf4 . Here, we show that the Wtf4 proteins can function outside of gametogenesis and in a distantly related species, Saccharomyces cerevisiae ...

Background: Alcohol consumption is an established risk factor for colorectal cancer (CRC). Identifying cofactor(s) that modulate the effect of alcohol on colon inflammation and carcinogenesis could help risk stratification for CRC. Disruption of circadian rhythm by light/dark shift promotes alcohol-induced colonic inflammation and cancer. More recently, we found that abnormal food timing causes circadian rhythm disruption and promotes alcohol associated colon carcinogenesis. In this study, we examined the interaction of wrong-time feeding (WTF) and alcohol on CRC-related pathways, in relation to changes in microbial community structure...

Killer meiotic drivers are genetic parasites that destroy 'sibling' gametes lacking the driver allele. The fitness costs of drive can lead to selection of unlinked suppressors. This suppression could involve evolutionary tradeoffs that compromise gametogenesis and contribute to infertility. Schizosaccharomyces pombe , an organism containing numerous gamete (spore)-killing wtf drivers, offers a tractable system to test this hypothesis. Here, we demonstrate that in scenarios analogous to outcrossing, wtf drivers generate a fitness landscape in which atypical spores, such as aneuploids and diploids, are advantageous...

Meiotic drivers are selfish alleles that can force their transmission into more than 50% of the viable gametes made by heterozygotes. Meiotic drivers are known to cause infertility in a diverse range of eukaryotes and are predicted to affect the evolution of genome structure and meiosis. The wtf gene family of Schizosaccharomyces pombe includes both meiotic drivers and drive suppressors and thus offers a tractable model organism to study drive systems. Currently, only a handful of wtf genes have been functionally characterized and those genes only partially reflect the diversity of the wtf gene family...

The exploitation of groundwater resources is of great importance and has become crucial in the last few decades, especially in arid regions, where surface water resources are scarce and unreliable. The Hexi Corridor (HC) is one of the most agriculturally rich and densely populated areas of arid northwestern China. Increasing demand for water, due to rapid population growth, oasis expansion and urbanization, has increased groundwater use, resulting in wide-scale depletion in this region. Sustainable management of aquifers in the HC requires accurate estimates of the current situation of groundwater resource sustainability...

This study investigated the occurrence and removals of micropollutants in the sewage treatment tank (STT) which is a typical private wastewater treatment facility used in the rural communities in Korea, and their impact on receiving water. STTs were selected in eight provinces to examine the regional difference in the composition of micropollutant occurrence. We measured ten selected micropollutants in influents and effluents of STTs, as well as upstream and downstream of its receiving surface water. The dominant micropollutants in the influent of the STTs were caffeine (13,346 ng/L), acetaminophen (11,331 ng/L), ibuprofen (1440 ng/L), and naproxen (1313 ng/L), in agreement with the amounts produced annually in Korea...

Water table fluctuation (WTF) methods are a primary and well-established way to determine groundwater recharge based on the direct response of the water table to precipitation input. An emerging complexity of recharge is whether it occurs as an episodic and transient process, or a continuous steady-state process, however most studies have not focused on these short-term vs. long-term timescales, in part because of a lack of data resolution. Here, high-resolution (subhourly) precipitation and water level data are analyzed for wells in the suburbs of New York City using two contrasting WTF approaches, with a common mathematical basis, that are suited to episodic and continuous processes...

Rett syndrome (RTT) is a neurodevelopmental disorder caused by mutation in the X-linked MECP2 gene. Random X-inactivation produces a mosaic of mutant (MT) and wild-type (WT) neurons in female Mecp2+/- (het) mice. Many RTT symptoms are alleviated by increasing activity in medial prefrontal cortex (mPFC) in RTT model mice (Howell et al., 2017). Using a GFP-MeCP2 fusion protein to distinguish WT from MT pyramidal neurons in mPFC we found cell autonomous (cell genotype specific) and non-autonomous effects of MeCP2 deficiency on spontaneous excitatory/inhibitory balance, nicotinic acetylcholine receptor (nAChR) currents and evoked activity...

This study presents an extension of the concept of "quasi-saturation" to a quasi-saturated layer, defined as the uppermost dynamic portion of the saturated zone subject to water table fluctuations. Entrapped air here may cause substantial reductions in the hydraulic conductivity (K) and fillable pore water. Air entrapment is caused by a rising water table, usually as a result of groundwater recharge. The most significant effects of entrapped air are recharge overestimation based on methods that use specific yield (Sy ), such as the water table fluctuation method (WTF), and reductions in K values...

Modern commercial pig production is a complex process that requires successful producers to understand and resolve factors associated with perturbations in production. One important perturbation is inventory loss due to mortality. In this study, data on 60 lots of approximately 2000 weaned pigs (n = 115,213) from one commercial production system were collected through the wean-to-finish (WTF) cycle with the objective of establishing patterns of mortality, estimating differences in profit/loss among patterns of mortality, and identifying production practices associated with mortality patterns...

Natural selection works best when the two alleles in a diploid organism are transmitted to offspring at equal frequencies. Despite this, selfish loci known as meiotic drivers that bias their own transmission into gametes are found throughout eukaryotes. Drive is thought to be a powerful evolutionary force, but empirical evolutionary analyses of drive systems are limited by low numbers of identified meiotic drive genes. Here, we analyze the evolution of the wtf gene family of Schizosaccharomyces pombe that contains both killer meiotic drive genes and suppressors of drive...

Human gait has been shown to be an effective biometric measure for person identification at a distance. On the other hand, changes in the view angle pose a major challenge for gait recognition as human gait silhouettes are usually different from different view angles. Traditionally, such a multi-view gait recognition problem can be tackled by View Transformation Model (VTM) which transforms gait features from multiple gallery views to the probe view so as to evaluate the gait similarity. In the real-world environment, however, gait sequences may be captured from an uncontrolled scene and the view angle is often unknown, dynamically changing, or does not belong to any predefined views (thus VTM becomes inapplicable)...

Small-angle X-ray scattering experiments were carried out to investigate the structural changes of cardiac thin filaments induced by the cardiomyopathy-causing E244D mutation in troponin T (TnT). We examined native thin filaments (NTF) from a bovine heart, reconstituted thin filaments containing human cardiac wild-type Tn (WTF), and filaments containing the E244D mutant of Tn (DTF), in the absence and presence of Ca2+ . Analysis by model calculation showed that upon Ca2+ -activation, tropomyosin (Tm) and Tn in the WTF and NTF moved together in a direction to expose myosin-binding sites on actin...

Meiotic drivers are selfish alleles that subvert gametogenesis to increase their transmission into progeny. Drivers impose a fitness cost, putting pressure on the genome to evolve suppressors. Here we investigate the wtf gene family from Schizosaccharomyces pombe, previously shown to contain meiotic drivers in wild isolates. We discovered that wtf13 found in lab stocks is a meiotic driver. wtf13 kills spores that do not inherit it by generating both a diffusible poison and a spore-specific antidote. Additionally, we demonstrate that wtf13 is suppressed by another wtf gene, wtf18-2, that arose spontaneously in the lab and makes only an antidote...

Determining groundwater recharge is in particular in areas with Monsoon rainfall a challenge. Several methods were used to estimate groundwater recharge for the first time ever for the urban area of Hanoi city, Vietnam. Water table fluctuation method (WTF), hydrograph analyses including recession curve displacement, graphical separation, the Automated Web GIS-Base Hydrology Analysis Tool (WHAT), and empirical formulas were utilized. The mean recharge is approximately 340 mm/year accounting for 20% of precipitation in the period 1996 to 2009 with a certain decrease during this period...

Fields, JB, Merrigan, JJ, White, JB, and Jones, MT. Body composition variables by sport and sport-position in elite collegiate athletes. J Strength Cond Res 32(11): 3153-3159, 2018-To assess body composition measures by sport and sport-position. Elite collegiate athletes participated (n = 475): men's and women's soccer (MSOC, n = 67; WSOC, n = 110); men's and women's swimming (MSWIM, n = 26; WSWIM, n = 22); men's and women's track and field (MTF, n = 29; WTF, n = 24); women's lacrosse and volleyball (WLAX, n = 84; WVB, n = 73); and baseball (BASE, n = 40)...

Meiotic drivers are selfish DNA loci that can bias their own transmission into gametes. Owing to their transmission advantages, meiotic drivers can spread in populations even if the drivers or linked variants decrease organismal fitness. Meiotic drive was first formally described in the 1950s and is thought to be a powerful force shaping eukaryotic genomes. Classic genetic analyses have detected the action of meiotic drivers in plants, filamentous fungi, insects and vertebrates. Several of these drive systems have limited experimental tractability and relatively little is known about the molecular mechanisms of meiotic drive...

Stabilization/Solidification (S/S) can be regarded as necessary for remediation of heavy metal contaminated soil. There is, however, solid agent is not very convenient to use. Water-soluble thiourea-formaldehyde (WTF) is a novel chelating agent, which has more practical applications. The process of WTF resin for S/S process of heavy metal contaminated soils was studied. Laboratory-prepared slurries, made of field soils spiked with Cd2+ and Cr6+ were treated with WTF resin. The toxicity characteristic leaching procedure (TCLP) showed that with 2 wt% WTF, in the neutral condition of soil after treatment for 7 d, the leaching concentrations of Cd2+ and Cr6+ in contaminated soil were decreased by 80...