keyword
MENU ▼
Read by QxMD icon Read
search

Gore

keyword
https://www.readbyqxmd.com/read/28822038/translocator-protein-pet-imaging-in-a-preclinical-prostate-cancer-model
#1
Mohammed N Tantawy, H Charles Manning, Todd E Peterson, Daniel C Colvin, John C Gore, Wenfu Lu, Zhenbang Chen, C Chad Quarles
PURPOSE: The identification and targeting of biomarkers specific to prostate cancer (PCa) could improve its detection. Given the high expression of translocator protein (TSPO) in PCa, we investigated the use of [(18)F]VUIIS1008 (a novel TSPO-targeting radioligand) coupled with positron emission tomography (PET) to identify PCa in mice and to characterize their TSPO uptake. PROCEDURES: Pten(pc-/-), Trp53(pc-/-) prostate cancer-bearing mice (n = 9, 4-6 months old) were imaged in a 7T MRI scanner for lesion localization...
August 18, 2017: Molecular Imaging and Biology: MIB: the Official Publication of the Academy of Molecular Imaging
https://www.readbyqxmd.com/read/28821007/measurement-tools-for-mental-health-problems-and-mental-well-being-in-people-with-severe-or-profound-intellectual-disabilities-a-systematic-review
#2
REVIEW
Samantha Flynn, Leen Vereenooghe, Richard P Hastings, Dawn Adams, Sally-Ann Cooper, Nick Gore, Chris Hatton, Kerry Hood, Andrew Jahoda, Peter E Langdon, Rachel McNamara, Chris Oliver, Ashok Roy, Vasiliki Totsika, Jane Waite
Mental health problems affect people with intellectual disabilities (ID) at rates similar to or in excess of the non-ID population. People with severe ID are likely to have persistent mental health problems. In this systematic review (PROSPERO 2015:CRD42015024469), we identify and evaluate the methodological quality of available measures of mental health problems or well-being in individuals with severe or profound ID. Electronic searches of ten databases identified relevant publications. Two reviewers independently reviewed titles and abstracts of retrieved records (n=41,232) and full-text articles (n=573)...
August 11, 2017: Clinical Psychology Review
https://www.readbyqxmd.com/read/28818517/ppar-agonists-for-primary-biliary-cholangitis
#3
Andrea A Gossard, Gregory J Gores
No abstract text is available yet for this article.
August 14, 2017: Lancet. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28816217/multispecialty-consensus-statement-for-primary-care-management-of-diabetic-foot-disease-in-india
#4
Arun Bal, Charudatta Chaudhari, Vijay Langer, Dipak Vyas, G Thulasikumar, Milind Ruke, Madhuri A Gore, Pinjala Ramakrishna, Rakesh K Khazanchi, S R Subrammaniyan, S Raja Sabapathy, Sanjay Desai, Sanjay Vaidya, Srikanth Vijayasimha, Sudhir Jain, Sunil Chaudhary, Sunil Kari, Tushar Rege
No abstract text is available yet for this article.
March 2017: National Medical Journal of India
https://www.readbyqxmd.com/read/28815398/characterization-of-host-response-resorption-and-strength-properties-and-performance-in-the-presence-of-bacteria-for-fully-absorbable-biomaterials-for-soft-tissue-repair
#5
N F N Stoikes, J R Scott, A Badhwar, C R Deeken, G R Voeller
PURPOSE: The objective was to evaluate the host response, resorption, and strength properties, and to assess the performance in the presence of bacteria for Phasix™ Mesh (Phasix™) and Gore(®) Bio-A(®) Tissue Reinforcement (Bio-A(®)) in preclinical models. METHODS: In a rat model, one mesh (2 × 2 cm) was implanted subcutaneously in n = 60 rats. Animals were euthanized after 2, 4, 8, 12, 16, or 24 weeks (n = 5/mesh/time point), and implant sites were assessed for host inflammatory response and overall fibrotic repair thickness...
August 16, 2017: Hernia: the Journal of Hernias and Abdominal Wall Surgery
https://www.readbyqxmd.com/read/28812687/community-structure-follows-simple-assembly-rules-in-microbial-microcosms
#6
Jonathan Friedman, Logan M Higgins, Jeff Gore
Microorganisms typically form diverse communities of interacting species, whose activities have tremendous impact on the plants, animals and humans they associate with. The ability to predict the structure of these complex communities is crucial to understanding and managing them. Here, we propose a simple, qualitative assembly rule that predicts community structure from the outcomes of competitions between small sets of species, and experimentally assess its predictive power using synthetic microbial communities composed of up to eight soil bacterial species...
March 27, 2017: Nature ecology & evolution
https://www.readbyqxmd.com/read/28812627/direct-observation-of-increasing-recovery-length-before-collapse-of-a-marine-benthic-ecosystem
#7
Luca Rindi, Martina Dal Bello, Lei Dai, Jeff Gore, Lisandro Benedetti-Cecchi
Ecosystems can experience catastrophic transitions to alternative states, yet recent results have suggested that slowing down in rates of recovery after a perturbation may provide advance warning that a critical transition is approaching. Perturbation experiments with microbial populations have supported this hypothesis under controlled laboratory conditions, but evidence from natural ecosystems remains rare. Here, we manipulated rocky intertidal canopy algae to test the hypothesis that the spatial scale at which the system recovers from a perturbation in space should increase as the system approaches the tipping point, marking the transition from a canopy-dominated to a turf-dominated state...
May 8, 2017: Nature ecology & evolution
https://www.readbyqxmd.com/read/28808884/outcomes-of-laparoscopic-hiatal-hernia-repair-in-nine-bariatric-patients-with-prior-sleeve-gastrectomy
#8
Francisco Igor B Macedo, Mia Mowzoon, Vijay K Mittal, Mubashir Sabir
BACKGROUND: Laparoscopic sleeve gastrectomy (LSG) may exacerbate gastroesophageal reflux disease (GERD) in patients with a hiatal hernia (HH). Surgical repair may be needed, however prior LSG precludes standard HH repair with fundoplication. METHODS: We retrospectively reviewed our experience with bariatric patients with prior LSG undergoing laparoscopic HH repair from August 2010 to July 2016. Patient demographics and outcomes including mortality, length of stay (LOS), readmission rates, reoperation, and complications were described...
August 14, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28807381/postoperative-initial-2-day-blood-pressure-management-facilitates-the-shrinkage-of-abdominal-aortic-aneurysm-after-endovascular-aneurysm-repair-by-reducing-the-incidence-of-type-ii-endoleak
#9
Shuhei Miura, Yoshihiko Kurimoto, Kosuke Ujihira, Yutaka Iba, Ryushi Maruyama, Akira Yamada, Masanori Nojima, Katsuhiko Nakanishi
OBJECTIVE: The aim of this study was to evaluate the effect of initial 2-day blood pressure management (BPM) after endovascular aneurysm repair (EVAR) for the incidence of subsequent type II endoleak (T2E) and shrinkage of abdominal aortic aneurysm (AAA) sac diameter. METHODS: We reviewed 136 patients who underwent EVAR for atherosclerotic AAA between July 2008 and July 2014 with one of three stent grafts (Excluder [W. L. Gore & Associates, Flagstaff, Ariz], Powerlink [Endologix Inc, Irvine, Calif], and Endurant [Medtronic Vascular, Santa Rosa, Calif])...
August 11, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28803865/ureaplasma-urealyticum-necrotizing-soft-tissue-infection
#10
Ian Gassiep, Letitia Gore, Joanne L Dale, E Geoffrey Playford
Ureaplasma urealyticum is a urogenital commensal and often associated with localised infection. With the advent of monoclonal immunosuppressive therapy and improved diagnostic methods, reports of non-urogenital infections are accumulating. We report a rare case of U. urealyticum necrotizing soft tissue infection and left hip septic arthritis in a hypogammaglobulinaemic patient. Consideration of this organism as an etiological agent, and potential early use of nucleic-acid diagnostic investigation with empiric therapy including activity against Ureaplasma in this patient population may be warranted...
August 10, 2017: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://www.readbyqxmd.com/read/28802066/targeting-senescent-cholangiocytes-and-activated-fibroblasts-with-bcl-xl-inhibitors-ameliorates-fibrosis-in-mdr2-mice
#11
Anja Moncsek, Mohammed S Al-Suraih, Christy E Trussoni, Steven P O'Hara, Patrick L Splinter, Camille Zuber, Eleonora Patsenker, Piero V Valli, Christian D Fingas, Achim Weber, Yi Zhu, Tamar Tchkonia, James L Kirkland, Gregory J Gores, Beat Müllhaupt, Nicholas F LaRusso, Joachim C Mertens
Cholangiocyte senescence has been linked to primary sclerosing cholangitis (PSC). Persistent secretion of growth factors by senescent cholangiocytes leads to the activation of stromal fibroblasts (ASF), which are drivers of fibrosis. The activated phenotype of ASF is characterized by an increased sensitivity to apoptotic stimuli. Here, we examined the mechanisms of apoptotic priming in ASF and explored a combined targeting strategy to deplete senescent cholangiocytes and ASF from fibrotic tissue to ameliorate liver fibrosis...
August 12, 2017: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
https://www.readbyqxmd.com/read/28789817/results-of-stent-graft-placement-to-treat-cephalic-arch-stenosis-in-hemodialysis-patients-with-dysfunctional-brachiocephalic-arteriovenous-fistulas
#12
Robert G Jones, Andrew P Willis, Karen Tullett, Peter L Riley
PURPOSE: To determine effectiveness of the VIABAHN (W.L. Gore & Associates, Flagstaff, Arizona) stent graft to treat cephalic arch stenosis in patients with dysfunctional brachiocephalic arteriovenous fistulas after inadequate venoplasty response. MATERIALS AND METHODS: Between 2012 and 2015, patients with failed venoplasty of symptomatic cephalic arch stenosis received a VIABAHN stent graft. Follow-up venography was performed at approximately 3, 6, and 12 months...
August 5, 2017: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/28783450/health-care-use-by-older-adults-with-acute-myeloid-leukemia-at-the-end-of-life
#13
Rong Wang, Amer M Zeidan, Stephanie Halene, Xiao Xu, Amy J Davidoff, Scott F Huntington, Nikolai A Podoltsev, Cary P Gross, Steven D Gore, Xiaomei Ma
Purpose Little is known about the patterns and predictors of the use of end-of-life health care among patients with acute myeloid leukemia (AML). End-of-life care is particularly relevant for older adults with AML because of their poor prognosis. Methods We performed a population-based, retrospective cohort study of patients with AML who were ≥ 66 years of age at diagnosis and diagnosed during the period from 1999 to 2011 and died before December 31, 2012. Medicare claims were used to assess patterns of hospice care and use of aggressive treatment...
August 7, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28782116/alcohol-use-among-concerned-partners-of-heavy-drinking-service-members-and-veterans
#14
Lindsey M Rodriguez, Karen Chan Osilla, Thomas E Trail, Kristie L Gore, Eric R Pedersen
Heavy drinking in relationships is complex and we focus on an understudied sample of concerned partners (CPs) worried about their U.S. service member/veteran partner's drinking. We evaluated the link between CP drinking and their own mental health, and how CP drinking moderated the efficacy of a web-based intervention designed to address CPs' mental health and communication. CPs (N = 234) were randomly assigned to intervention or control and completed assessments at baseline and 5 months later. CP drinking was associated with greater CP depression, anxiety, and anger independent of partner drinking...
August 7, 2017: Journal of Marital and Family Therapy
https://www.readbyqxmd.com/read/28764290/wheatgrass-green-blood-can-help-to-fight-cancer
#15
Rucha Diwakar Gore, Sangeeta Jayant Palaskar, Anirudha Ratnadeep Bartake
INTRODUCTION: Oral squamous cell carcinoma is the sixth most common cancer worldwide and is one of the leading causes of death especially in developing countries like India. It is usually managed with the help of chemotherapeutic agents that are toxic not only to the tumor cells but also to normal cells in many ways. Whereas the traditional herbal medicines which are used from ancient days in India are generally known to be free of toxic effects and are effective. Wheatgrass is the young grass of the wheat plant 'Tritcumaestivum Linn', family Poaceae (Gramineae)...
June 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28759108/a-call-for-action-increasing-enrollment-of-untreated-patients-with-higher-risk-myelodysplastic-syndromes-in-first-line-clinical-trials
#16
REVIEW
Amer M Zeidan, Maximilian Stahl, Mikkael A Sekeres, David P Steensma, Rami S Komrokji, Steven D Gore
Hypomethylating agents (HMAs) have changed the landscape of the management of patients with higher-risk myelodysplastic syndromes (HR-MDS). HMAs have improved hematopoiesis and quality of life and, in the case of azacitidine, prolonged survival in a large randomized trial. However, multiple real-life and registry analyses have demonstrated minimal survival gains at the population level after the approval of HMAs. Furthermore, the 24-month median survival observed with azacitidine in the landmark AZA-001 trial has not been replicated in population-based studies or in other clinical trials using azacitidine monotherapy arms...
July 31, 2017: Cancer
https://www.readbyqxmd.com/read/28754102/how-active-are-women-who-play-bingo-a-cross-sectional-study-from-the-well-bingo-project
#17
Gemma C Ryde, Trish Gorely, Ruth Jepson, Cindy Gray, Ashley Shepherd, Dionne Mackison, Aileen V Ireland, Brian Williams, Marion E T McMurdo, Josie M M Evans
BACKGROUND: The benefits of physical activity are well established, yet large numbers of people are not sufficiently active to gain health benefits. Certain population groups are less physically active than others, including older women from areas of high economic deprivation. The Well!Bingo project was established with the aim of engaging such women in the development of a health promotion intervention in a bingo club. This paper reports on the assessment of health status, physical activity and sedentary behaviour of women attending a bingo club in central Scotland, UK as part of the Well!Bingo project...
July 28, 2017: BMC Women's Health
https://www.readbyqxmd.com/read/28753173/the-wfsa-global-anesthesia-workforce-survey
#18
Peter Kempthorne, Wayne W Morriss, Jannicke Mellin-Olsen, Julian Gore-Booth
BACKGROUND: Safe anesthesia and surgical care are not available when needed for 5 billion of the world's 7 billion people. There are major deficiencies in the specialist surgical workforce in many parts of the world, and specific data on the anesthesia workforce are lacking. METHODS: The World Federation of Societies of Anaesthesiologists conducted a workforce survey during 2015 and 2016. The aim of the survey was to collect detailed information on physician anesthesia provider (PAP) and non-physician anesthesia provider (NPAP) numbers, distribution, and training...
September 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28751202/r1%C3%AF-dispersion-and-sodium-imaging-in-human-calf-muscle
#19
Ping Wang, He Zhu, Hakmook Kang, John C Gore
PURPOSE: To evaluate the magnitude of chemical exchange effects and R1ρ dispersion in muscle and their relationship to tissue sodium levels with aging. METHODS: Seven healthy volunteers (aged 24 to 87years, median age 47) underwent MRI to assess tissue sodium levels and water T1ρ values at different spin-locking frequencies in calf muscles. T1ρ values at each locking field were computed based on a three-parameter mono-exponential model to fit signals obtained at different locking times, and R1ρ (=1/T1ρ) rates were compared at different locking fields...
July 24, 2017: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/28749903/drug-development-for-rare-cancers-in-children
#20
Lia Gore
No abstract text is available yet for this article.
June 2017: Clinical Advances in Hematology & Oncology: H&O
keyword
keyword
12224
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"