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https://www.readbyqxmd.com/read/29150477/risk-factors-for-recurrent-intussusception-in-children-a-retrospective-cohort-study
#1
Wan-Liang Guo, Zhang-Chun Hu, Ya-Lan Tan, Mao Sheng, Jian Wang
OBJECTIVE: The aim of this study was to assess the frequency of clinical features and pathological lead points in recurrent intussusception, with a special focus on the risk factors that lead to recurrent intussusception. DESIGN: This is a retrospective cohort study. A 5-year retrospective study was performed between January 2012 and July 2016 in the Children's Hospital of Soochow University, Suzhou, China, to determine the clinical features and pathological lead points of recurrent intussusception...
November 16, 2017: BMJ Open
https://www.readbyqxmd.com/read/29142801/idiopathic-acquired-dacryocystocele-presenting-only-with-epiphora-a-very-rare-case-report
#2
Muhammad Jahanzaib Anwar, Saad A Choudhry, Muhammad Aadil, Ahmer Asif, Atif Ameer
A 42-years-old male presented with left medial canthal swelling, accompanied with only mild epiphora. There was no history of dacryocystitis, mid-facial trauma, surgery, or bloody tears. On examination, there was an immobile, subcutaneous, non-inflammatory mass below the medial canthal tendon. Lacrimal irrigation showed blockade at the nasolacrimal duct. A computerized axial tomography (CAT) scan revealed a non-enhancing, low-density, cystic lesion at the inferomedial margin of the orbit. There were no signs of bony erosion, consistent with idiopathic acquired dacryocystocele...
September 4, 2017: Curēus
https://www.readbyqxmd.com/read/29138740/pediatric-pulmonary-hemorrhage-vs-extrapulmonary-bleeding-in-the-differential-diagnosis-of-hemoptysis
#3
Michael Vaiman, Baruch Klin, Noa Rosenfeld, Ibrahim Abu-Kishk
Introduction: Hemoptysis is an important symptom which causes a major concern, and warrants immediate diagnostic attention. The authors compared a group of patients with pediatric pulmonary hemorrhage with pediatric patients diagnosed with extrapulmonary bleeding focusing on differences in etiology, outcome and differential diagnosis of hemoptysis. Methods: We performed the retrospective analysis of medical charts of 134 pediatric patients admitted to the Emergency Department because of pulmonary and extrapulmonary hemorrhage and were diagnosed with suspected hemoptysis or developed hemoptysis (ICD10-CM code R04...
2017: Central Asian Journal of Global Health
https://www.readbyqxmd.com/read/29132613/identification-and-management-of-shigella-infection-in-children-with-diarrhoea-a-systematic-review-and-meta-analysis
#4
Kirkby D Tickell, Rebecca L Brander, Hannah E Atlas, Jeffrey M Pernica, Judd L Walson, Patricia B Pavlinac
BACKGROUND: Shigella infections are a leading cause of diarrhoeal death among children in low-income and middle-income countries. WHO guidelines reserve antibiotics for treating children with dysentery. Reliance on dysentery for identification and management of Shigella infection might miss an opportunity to reduce Shigella-associated morbidity and mortality. We aimed to systematically review and evaluate Shigella-associated and dysentery-associated mortality, the diagnostic value of dysentery for the identification of Shigella infection, and the efficacy of antibiotics for children with Shigella or dysentery, or both...
December 2017: Lancet Global Health
https://www.readbyqxmd.com/read/29124041/alteration-of-gut-microbiota-and-inflammatory-cytokine-chemokine-profiles-in-5-fluorouracil-induced-intestinal-mucositis
#5
Hong-Li Li, Lan Lu, Xiao-Shuang Wang, Li-Yue Qin, Ping Wang, Shui-Ping Qiu, Hui Wu, Fei Huang, Bei-Bei Zhang, Hai-Lian Shi, Xiao-Jun Wu
Disturbed homeostasis of gut microbiota has been suggested to be closely associated with 5-fluorouracil (5-Fu) induced mucositis. However, current knowledge of the overall profiles of 5-Fu-disturbed gut microbiota is limited, and so far there is no direct convincing evidence proving the causality between 5-Fu-disturbed microbiota and colonic mucositis. In mice, in agreement with previous reports, 5-Fu resulted in severe colonic mucositis indicated by weight loss, diarrhea, bloody stool, shortened colon, and infiltration of inflammatory cells...
2017: Frontiers in Cellular and Infection Microbiology
https://www.readbyqxmd.com/read/29121863/multiplex-real-time-pcr-assay-for-detection-of-escherichia-coli-o157-h7-and-screening-for-non-o157-shiga-toxin-producing-e-coli
#6
Baoguang Li, Huanli Liu, Weimin Wang
BACKGROUND: Shiga toxin-producing Escherichia coli (STEC), including E. coli O157:H7, are responsible for numerous foodborne outbreaks annually worldwide. E. coli O157:H7, as well as pathogenic non-O157:H7 STECs, can cause life-threating complications, such as bloody diarrhea (hemolytic colitis) and hemolytic-uremic syndrome (HUS). Previously, we developed a real-time PCR assay to detect E. coli O157:H7 in foods by targeting a unique putative fimbriae protein Z3276. To extend the detection spectrum of the assay, we report a multiplex real-time PCR assay to specifically detect E...
November 9, 2017: BMC Microbiology
https://www.readbyqxmd.com/read/29120301/antimicrobial-susceptibility-virulence-potential-and-sequence-types-associated-with-arcobacter-strains-recovered-from-human-faeces
#7
Alba Pérez-Cataluña, Josepa Tapiol, Clara Benavent, Carolina Sarvisé, Frederic Gómez, Bruno Martínez, Margarida Terron-Puig, Gemma Recio, Angels Vilanova, Isabel Pujol, Frederic Ballester, Antonio Rezusta, María Jose Figueras
PURPOSE: The genus Arcobacter includes bacteria that are considered emergent pathogens because they can produce infections in humans and animals. The most common symptoms are bloody and non-bloody persistent diarrhea but cases with abdominal cramps without diarrhea or asymptomatic cases have also been described as well as cases with bacteremia. The objective was to characterize Arcobacter clinical strains isolated from the faeces of patients from three Spanish hospitals. METHODOLOGY: We have characterized 28 clinical strains (27 of A...
November 9, 2017: Journal of Medical Microbiology
https://www.readbyqxmd.com/read/29116292/first-isolation-report-of-arcobacter-cryaerophilus-from-a-human-diarrhea-sample-in-costa-rica
#8
Karol Barboza, Zaida Cubillo, Eduardo Castro, Mauricio Redondo-Solano, Heriberto Fernández-Jaramillo, María Laura Arias Echandi
Arcobacter cryaerophilus is an emerging enteropathogen and potential zoonotic agent transmitted by food and water. In Costa Rica, this bacterium has not been associated with cases of human gastroenteritis, even though it has been isolated from farm animals, especially poultry. This paper reports the first isolation of A. cryaerophilus from a human case of bloody watery diarrhea and the virulence genes associated with this isolate.
November 6, 2017: Revista do Instituto de Medicina Tropical de São Paulo
https://www.readbyqxmd.com/read/29114931/thrombotic-microangiopathy-with-concomitant-gi-agvhd-after-allogeneic-hematopoietic-stem-cell-transplantation-risk-factors-and-outcome
#9
Xiao-Hui Zhang, Xiao Liu, Qin-Ming Wang, Yun He, Xiao-Lu Zhu, Jia-Min Zhang, Wei Han, Huan Chen, Yu-Hong Chen, Feng-Rong Wang, Jing-Zhi Wang, Yuan-Yuan Zhang, Xiao-Dong Mo, Yao Chen, Yu Wang, Hai-Xia Fu, Ying-Jun Chang, Lan-Ping Xu, Kai-Yan Liu, Xiao-Jun Huang
OBJECTIVES: To explore the possible risk factors for the occurrence and mortality of TMA with concomitant aGVHD and to investigate outcomes and treatments of this disorder after allo-HSCT. METHODS: 50 cases diagnosed with TMA with concomitant aGVHD and 150 controls were identified from a cohort composed of 3 992 patients who underwent allo-HSCT from 2008 to 2016. RESULTS: Grade III-IV aGVHD (p=0.000), acute kidney injury (AKI) (p=0.033) and hypertension (p=0...
November 7, 2017: European Journal of Haematology
https://www.readbyqxmd.com/read/29104199/-surgical-treatment-for-myocardial-rerupture-after-repair-of-post-infarction-left-ventricular-free-wall-rupture
#10
Chikashi Aoki, Kengo Tani, Ryou Taguchi, Ryousuke Kowatari, Norihiro Kondo, Masahito Minakawa, Ikuo Fukuda
A 73-year-old man was admitted for cardiac tamponade by oozing type left ventricular free wall rupture associated with acute myocardial infarction. Transthoracic echocardiography demonstrated moderate pericardial effusion and the presence of pseudoaneurysm within posterior wall. He went into shock with a systolic blood pressure of 60 mmHg. After introducing percutaneous cardiopulmonary support and intraaortic balloon pump, the sutureless repair was performed immediately. After having rehabilitation for right-sided hemiparesis, an elective pseudoaneurysm repair was planned...
November 2017: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/29098132/mycotic-pseudoaneurysm-associated-with-skull-base-osteomyelitis-treated-with-endovascular-embolization
#11
Ali S Haider, Brandon I Esianor, Mrigank S Shail, Margaret I Engelhardt, Aida Kafai Golahmadi, Ramiz Khan, Umair Khan, Steven Vayalumkal, Richa Thakur, Kennith F Layton
Pseudoaneurysms occur due to malformations in arterial wall uniformity, leading to blood collection between the outer arterial layers and resultant outpouching of the vessel. Unlike true aneurysms, pseudoaneurysms do not involve all layers of the blood vessel. Mycotic pseudoaneurysms can occur after associated vessel adventitia infection, leading to transmural dissection. Here we present a case of a 78-year-old man with a history of chronic otitis externa and osteomyelitis who presented with increasing right ear pain with bloody discharge and associated headache...
August 28, 2017: Curēus
https://www.readbyqxmd.com/read/29096349/extramedullary-hematopoiesis-mimicking-mediastinal-tumor-in-a-patient-with-hereditary-spherocytosis-case-report
#12
Jae Bum Park, Song Am Lee, Yo Han Kim, Woo Surng Lee, Jae Joon Hwang
INTRODUCTION: Extramedullary hematopoiesis (EMH) is a rare disorder, defined as the appearance of hematopoietic elements outside the bone marrow or peripheral blood. The exact mechanism of this development is still unknown. We herein report a case of intrathoracic EMH, manifesting as a posterior mediastinal tumor in a patient with hereditary spherocytosis. PRESENTATION OF CASE: A 45-year-old man who presented with anemia, jaundice and abdominal pain was diagnosed with hereditary spherocytosis...
October 27, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29092986/the-analysis-of-synovial-fluid-in-total-knee-arthroplasties-with-flexion-instability
#13
N M Hernandez, M J Taunton, K I Perry, K C Mara, A D Hanssen, M P Abdel
AIMS: Patients with flexion instability after total knee arthroplasty (TKA) often present with a recurrent effusion, which may be a haemarthrosis. While the radiographic factors contributing to flexion instability have been elucidated, the clinical diagnosis remains challenging. Our aim, in this study, was to determine the mean white cell count and differential profile in pre-operative aspirations of synovial fluid in a consecutive series of patients undergoing revision TKA for flexion instability...
November 2017: Bone & Joint Journal
https://www.readbyqxmd.com/read/29079372/positive-guaiac-and-bloody-stool-are-poor-predictors-of-intussusception
#14
Amir A Kimia, Scotty Williams, Peter N Hadar, Assaf Landschaft, John Porter, Richard G Bachur
BACKGROUND: Currant jelly stool is a late manifestation of intussusception and is rarely seen in clinical practice. Other forms of GI bleeding have not been thoroughly studied and little is known about their respective diagnostic values. OBJECTIVE: To assess the predictive value of GI bleeding (positive guaiac test, bloody stool and rectal bleeding in evaluation of intussusception. METHODS: We performed a retrospective cross-sectional study cohort of all children, ages 1month-6years of age, who had an abdominal ultrasound obtained evaluating for intussusception over 5year period...
October 18, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29079313/the-effect-of-gestational-age-on-clinical-and-radiological-presentation-of-necrotizing-enterocolitis
#15
Elena Palleri, Ida Aghamn, Tomas S Bexelius, Marco Bartocci, Tomas Wester
BACKGROUND/PURPOSE: To test the hypothesis that clinical and radiological features of necrotizing enterocolitis vary with gestational age in all neonates with NEC and in subgroup of surgically treated patients. METHODS: This was a retrospective study case series. NEC cases treated in Stockholm County from 2009 to 2014 were identified in the National Quality Register. Patients were included in the study if they had a verified NEC diagnosis and they were divided into 2 groups according to the gestational age...
October 8, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29076895/primary-pericardial-angiosarcoma-shown-on-fdg-pet-ct
#16
Ximin Shi, Fang Li
A 63-year-old woman had persistent bloody pericardial effusion. Tuberculous pericarditis was initially suspected, but empirical antituberculosis therapy was futile. FDG PET/CT study revealed abnormal FDG activity in multiple parts of the pericardium, especially along with aorta and main pulmonary artery, and in the left atrium. However, there was no abnormal activity in other parts of the body. Histopathologic examination revealed primary pericardial angiosarcoma.
October 26, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/29076685/causes-of-lower-gastrointestinal-bleeding-on-colonoscopy
#17
Attique-Ur-Rehman Jehangiri, Rahid Gul, Rania Hadayat, Adil Naseer Khan, Zabiullah, Liaqat Khursheed
BACKGROUND: Bleeding from anus is usually referred as rectal bleeding but actually rectal bleeding is defined as bleeding from lower colon or rectum, which means bleeding from a place distal to ligament of Treitz. This study was conducted to determine the frequency of different causes of rectal bleeding in patients at Ayub Teaching Hospital, Abbottabad. METHODS: One hundred and seventy-five patients with evidence of rectal bleed, without gender discrimination were selected by non-probability convenient sampling from the out-patient department and general medical wards...
July 2017: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/29067041/paediatric-inflammatory-bowel-disease-clinical-presentation-and-disease-location
#18
Danish Abdul Aziz, Maryum Moin, Atif Majeed, Kamran Sadiq, Abdul Gaffar Biloo
OBJECTIVE: To determine different clinical presentationsand disease location demarcatedby upper and lower gastrointestinal endoscopyand relevant histopathologyin children diagnosed with inflammatory bowel disease (IBD). METHODS: This is 5 years (2010 to 2015) retrospective studyconducted at the Aga Khan University Hospitalenrolling65admitted children between 6 months to 15years from either gender, diagnosed with IBD on clinical presentation, endoscopy and biopsy...
July 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/29063990/identification-and-biochemical-characterization-of-wbwb-a-novel-udp-gal-neu5ac-r-%C3%AE-1-4-galactosyltransferase-from-the-intestinal-pathogen-escherichia-coli-serotype-o104
#19
Diana Czuchry, Walter A Szarek, Inka Brockhausen
The intestinal pathogen Escherichia coli serotype O104:H4 (ECO104) can cause bloody diarrhea and haemolytic uremic syndrome. The ECO104 O antigen has the unique repeating unit structure [4Galα1-4Neu5,7,9Ac3α2-3Galβ1-3GalNAcβ1-], which includes the mammalian sialyl-T antigen as an internal structure. Previously, we identified WbwC from ECO104 as the β3Gal-transferase that synthesizes the T antigen, and showed that α3-sialyl-transferase WbwA transfers sialic acid to the T antigen. Here we identify the wbwB gene product as a unique α1,4-Gal-transferase WbwB that transfers Gal from UDP-Gal to the terminal sialic acid residue of Neu5Acα2-3Galβ1-3GalNAcα-diphosphate-lipid acceptor...
October 24, 2017: Glycoconjugate Journal
https://www.readbyqxmd.com/read/29061148/integrated-community-case-management-by-drug-sellers-influences-appropriate-treatment-of-paediatric-febrile-illness-in-south-western-uganda-a-quasi-experimental-study
#20
Freddy Eric Kitutu, Joan Nakayaga Kalyango, Chrispus Mayora, Katarina Ekholm Selling, Stefan Peterson, Henry Wamani
BACKGROUND: Fever case management is a major challenge for improved child health globally, despite existence of cheap and effective child survival health technologies. The integrated Community Case Management (iCCM) intervention of paediatric febrile illnesses though adopted by Uganda's Ministry of Health to be implemented by community health workers, has not addressed the inaccess to life-saving medicines and diagnostics. Therefore, the iCCM intervention was implemented in private drug shops and evaluated for its effect on appropriate treatment of paediatric fever in a low malaria transmission setting in South Western Uganda...
October 23, 2017: Malaria Journal
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