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https://www.readbyqxmd.com/read/29351642/caregiver-provided-physical-therapy-home-programs-for-children-with-motor-delay-a-scoping-review
#1
Edward James R Gorgon
Background: Caregiver-provided physical therapy home programs (PTHP) play an important role in enhancing motor outcomes in pediatric patient populations. Purpose: This scoping review systematically mapped clinical trials of caregiver-provided PTHP that were aimed at enhancing motor outcomes in children who have or who are at risk for motor delay, with the purpose of (1) describing trial characteristics; (2) assessing methodologic quality, and (3) examining the reporting of caregiver-related components...
January 17, 2018: Physical Therapy
https://www.readbyqxmd.com/read/29351630/prevalence-and-trends-of-transfusion-transmittable-infections-among-blood-donors-in-southwest-china
#2
Ting Xu, Zhong-Mei Yi, Jun-Mei Luo, He-Lian Yu, Ya-Han Fan, Hua Lu, Shu-Ming Zhao, Tian-Lun Jiang
Background: The high prevalence of transfusion-transmitted infections (TTIs) is causing serious harm to human health worldwide. The aim of this research was to assess the prevalence and influencing factors of TTIs in Southwest China. Methods: A retrospective study of blood donor records from January 2008 to December 2015 was conducted. All samples were screened for HBV, HCV, HIV and syphilis. The donor's data was recorded and analyzed statistically using SPSS software...
January 17, 2018: Journal of Public Health
https://www.readbyqxmd.com/read/29351610/orthotopic-branched-endovascular-aortic-arch-repair-in-patients-who-cannot-undergo-classical-surgery
#3
Martin Czerny, Bartosz Rylski, Julia Morlock, Holger Schröfel, Friedhelm Beyersdorf, Bertrand Saint Lebes, Olivier Meyrignac, Fatima Mokrane, Mario Lescan, Christian Schlensak, Constatijn Hazenberg, Trijntje Bloemert-Tuin, Sue Braithwaite, Joost van Herwaarden, Herve Rousseau
OBJECTIVES: Our goal was to assess the results after orthotopic branched endovascular aortic arch repair using a new double-branch endoprosthesis in patients with thoracic aortic disease affecting the aortic arch who cannot undergo classical surgery. METHODS: Within a 4-year period, 15 patients with thoracic aortic disease affecting the aortic arch were treated with the Bolton Relay plus double-branch endoprosthesis (Bolton Medical, Sunrise, FL, USA). We assessed clinical outcome, occurrence of endoleaks and the need for secondary interventions...
January 16, 2018: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29351597/a-systematic-review-of-health-promotion-interventions-to-increase-breast-cancer-screening-uptake-from-the-last-12-years
#4
Feleke Doyore Agide, Roya Sadeghi, Gholamreza Garmaroudi, Bereket Molla Tigabu
Background: The outcome of breast cancer treatment largely depends on the timing of detection. The health promotion interventions have an immense contribution to early detection and improved survival. Therefore, this review aimed to provide evidence on the efficacy of the health promotion interventions to increase the uptake of breast cancer screening and to develop effective interventions targeting women. Methods: Online databases (PubMed/MEDLINE/PubMed Central, Ovid/MEDILINE, EMBASE, Web of Science and Google Scholar) were searched for studies published between January 2005 and January 2017...
January 16, 2018: European Journal of Public Health
https://www.readbyqxmd.com/read/29351596/freedom-solo%C3%A2-versus-trifecta%C3%A2-bioprostheses-clinical-and-haemodynamic-evaluation-after-propensity-score-matching
#5
Rui J Cerqueira, Renata Raimundo, Soraia Moreira, Francisca A Saraiva, Marta Andrade, Elson Salgueiro, Jorge Almeida, Mário Jorge Amorim, Paulo Pinho, André P Lourenço, Adelino Leite-Moreira
OBJECTIVES: The goal of this study was to compare the stentless Freedom Solo® (FS) and the stented Trifecta® (TF) aortic bioprostheses with regard to haemodynamic profile, left ventricular mass regression and early and late postoperative outcomes and survival. METHODS: A longitudinal cohort study of consecutive patients undergoing aortic valve replacement (2009-16) with either the FS or TF at 1 centre was performed. Local databases and national records were queried...
January 16, 2018: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29351456/guidelines-for-measuring-cardiac-physiology-in-mice
#6
Merry L Lindsey, Zamaneh Kassiri, Jitka Amira Ismail Virag, Lisandra E de Castro Bras, Marielle Scherrer-Crosbie
Cardiovascular disease is a leading cause of death, and translational research is needed to better understand mechanisms whereby the left ventricle responds to injury. Mouse models of heart disease have provided valuable insights into mechanisms that occur during cardiac aging and in response to a variety of pathologies. Assessing cardiovascular physiological responses to injury or insult is an important and necessary component of this research. With increasing consideration for rigor and reproducibility, the goal of this guidelines review is to provide best practice information regarding how to accurately measure cardiac physiology in animal models...
January 5, 2018: American Journal of Physiology. Heart and Circulatory Physiology
https://www.readbyqxmd.com/read/29351455/thrombosis-systemic-and-cardiac-oxidative-stress-and-dna-damage-induced-by-pulmonary-exposure-to-diesel-exhaust-particles-and-the-effect-of-nootkatone-thereon
#7
Abderrahim Nemmar, Suhail Al-Salam, Sumaya Beegam, Priya Yuvaraju, Badreldin H Ali
Adverse cardiovascular effects of particulate air pollution persist even at lower concentrations than those of the current air quality limit. Therefore, identification of safe and effective measures against particles-induced cardiovascular toxicity is needed. Nootkatone is a sesquiterpenoid in grapefruit with diverse bioactivities including anti-inflammatory and antioxidant effects. However, its protective effect on the cardiovascular injury induced by diesel exhaust particles (DEP) has not been studied before...
January 5, 2018: American Journal of Physiology. Heart and Circulatory Physiology
https://www.readbyqxmd.com/read/29351416/acute-and-chronic-resistance-training-downregulates-select-line-1-retrotransposon-activity-markers-in-human-skeletal-muscle
#8
Matthew A Romero, C Brooks Mobley, Petey W Mumford, Paul A Roberson, Cody T Haun, Wesley C Kephart, James C Healy, Darren T Beck, Kaelin C Young, Jeffrey S Martin, Christopher M Lockwood, Michael D Roberts
Herein, we examined if acute or chronic resistance exercise affected markers of skeletal muscle LINE-1 retrotransposon activity. In study 1, 10 resistance-trained college-aged males performed three consecutive daily back squat sessions, and vastus lateralis biopsies were taken prior to (Pre), 2 h following session 1 (Post1), and 3 days following session 3 (Post2). In study 2, 13 untrained college-aged males performed a full-body resistance training program (3 d/wk), and vastus lateralis biopsies were taken prior to (week 0) and ~72 h following training cessation (week 12)...
December 20, 2017: American Journal of Physiology. Cell Physiology
https://www.readbyqxmd.com/read/29351396/mechanisms-of-repetitive-retrograde-contractions-in-response-to-sustained-esophageal-distension-a-study-evaluating-patients-with-post-fundoplication-dysphagia
#9
Dustin A Carlson, Peter J Kahrilas, Katherine Ritter, Zhiyue Lin, John E Pandolfino
BACKGROUND: Repetitive, retrograde contractions (RRCs) in response to sustained esophageal distension are a distinct contractility pattern observed with functional luminal imaging probe (FLIP) panometry that are common in type III (spastic) achalasia. RRCs are hypothesized to be indicative of either impaired inhibitory innervation or esophageal outflow obstruction. We aimed to apply FLIP panometry to patients with post-fundoplication dysphagia (a model of esophageal obstruction) to explore mechanisms behind RRCs...
December 21, 2017: American Journal of Physiology. Gastrointestinal and Liver Physiology
https://www.readbyqxmd.com/read/29351367/accurate-understanding-of-infertility-risk-among-families-of-adolescent-males-newly-diagnosed-with-cancer
#10
Vicky Lehmann, Jessica S Flynn, Rebecca H Foster, Kathryn M Russell, James L Klosky
OBJECTIVE: To examine patient and parent understanding of infertility risk (relative to oncologists' risk ratings) among adolescents newly diagnosed with cancer, and to identify background factors related to inaccurate reporting/estimating. METHODS: Male patients (N=137; aged 13-21) and their parents completed self-report questionnaires. Those who reported a fertility-related conversation with their provider (N=102 adolescents, N=74 parents), reported their infertility risk (i...
January 19, 2018: Psycho-oncology
https://www.readbyqxmd.com/read/29351338/stockouts-of-hiv-commodities-in-public-health-facilities-in-kinshasa-barriers-to-end-hiv
#11
Tinne Gils, Claire Bossard, Kristien Verdonck, Philip Owiti, Ilse Casteels, Maria Mashako, Gilles Van Cutsem, Tom Ellman
Stockouts of HIV commodities increase the risk of treatment interruption, antiretroviral resistance, treatment failure, morbidity and mortality. The study objective was to assess the magnitude and duration of stockouts of HIV medicines and diagnostic tests in public facilities in Kinshasa, Democratic Republic of the Congo. This was a cross-sectional survey involving visits to facilities and warehouses in April and May 2015. All zonal warehouses, all public facilities with more than 200 patients on antiretroviral treatment (ART) (high-burden facilities) and a purposive sample of facilities with 200 or fewer patients (low-burden facilities) in Kinshasa were selected...
2018: PloS One
https://www.readbyqxmd.com/read/29351312/prognostic-relevance-of-elevated-pulmonary-arterial-pressure-assessed-non-invasively-analysis-in-a-large-patient-cohort-with-invasive-measurements-in-near-temporal-proximity
#12
Sebastian Greiner, Andreas Jud, Matthias Aurich, Christoph Geisenberger, Lorenz Uhlmann, Thomas Hilbel, Meinhard Kieser, Hugo A Katus, Derliz Mereles
BACKGROUND: The clinical relevance of non-invasively derived pulmonary arterial pressure (PAP) by Doppler echocardiography (DE) has been questioned in the past. However, transthoracic echocardiography is used as a cornerstone examination for patients with dyspnea and suspected pulmonary hypertension (PH). This study aimed to evaluate the prognostic value of non-invasive assessed PAP in a large population of patients with known or suspected cardiopulmonary disease. METHODS: The analyses are based on data of patients of a tertiary cardiology center that received right heart catheterization (RHC) as well as non-invasively assessed PAP by DE within five days, and includes serological and clinical parameters in a retrospective follow-up for up to eight years...
2018: PloS One
https://www.readbyqxmd.com/read/29351311/the-quality-of-voluntary-medical-male-circumcision-done-by-mid-level-workers-in-tshwane-district-south-africa-a-retrospective-analysis
#13
Sanele Ngcobo, Jacqueline Elizabeth Wolvaardt, Martin Bac, Elize Webb
BACKGROUND: Voluntary medical male circumcision (VMMC) reduces the acquisition of human immunodeficiency virus (HIV) in heterosexual men by up to 60%. One HIV infection is averted for every 5 to 15 VMMCs. To conduct VMMCs in large populations, large numbers of trained healthcare professionals are needed. Countries in Sub-Saharan Africa have a high burden of HIV and a shortage of healthcare professionals, creating a healthcare conundrum. To bridge this gap, South Africa launched a new cadre of mid-level medical worker called Clinical Associates (CA)...
2018: PloS One
https://www.readbyqxmd.com/read/29351295/effects-of-a-population-based-person-centred-and-integrated-care-service-on-health-wellbeing-and-self-management-of-community-living-older-adults-a-randomised-controlled-trial-on-embrace
#14
Sophie L W Spoorenberg, Klaske Wynia, Ronald J Uittenbroek, Hubertus P H Kremer, Sijmen A Reijneveld
OBJECTIVE: To evaluate the effects of the population-based, person-centred and integrated care service 'Embrace' at twelve months on three domains comprising health, wellbeing and self-management among community-living older people. METHODS: Embrace supports older adults to age in place. A multidisciplinary team provides care and support, with intensity depending on the older adults' risk profile. A randomised controlled trial was conducted in fifteen general practices in the Netherlands...
2018: PloS One
https://www.readbyqxmd.com/read/29351277/ex-ante-assessment-of-different-vaccination-based-control-schedules-against-the-peste-des-petits-ruminants-virus-in-sub-saharan-africa
#15
Pachka Hammami, Renaud Lancelot, Joseph Domenech, Matthieu Lesnoff
BACKGROUND: Peste des petits ruminants (PPR) is a highly contagious and widespread viral infection of small ruminants (goats and sheep), causing heavy economic losses in many developing countries. Therefore, its progressive control and global eradication by 2030 was defined as a priority by international organizations addressing animal health. The control phase of the global strategy is based on mass vaccination of small ruminant populations in endemic regions or countries. It is estimated that a 70% post-vaccination immunity rate (PVIR) is needed in a given epidemiological unit to prevent PPR virus spread...
2018: PloS One
https://www.readbyqxmd.com/read/29351178/using-time-referenced-data-to-assess-medication-administration-performance-and-quality
#16
John M Welton, Catherine Kleiner, Carolyn Valdez, Sara Richardson, Kathy Boyle, Eric Lucas
OBJECTIVE: This study tests the feasibility of using a large (big) clinical data set to test the ability to extract time-referenced data related to medication administration to identify late doses and as-needed (PRN) administration patterns by RNs in an inpatient setting. METHODS: The study is a secondary analysis of a set of data using bar-code medication administration time stamps (n = 3043812) for 50883 patients admitted to a single, urban, 525-bed hospital in 11 inpatient units by 714 nurses between April 1, 2013, and March 31, 2015...
February 2018: Journal of Nursing Administration
https://www.readbyqxmd.com/read/29351139/a-pilot-randomized-controlled-trial-of-a-phone-based-intervention-for-smoking-cessation-and-relapse-prevention-in-the-postpartum-period
#17
Victoria H Coleman-Cowger, Katrina S Mark, Zachary R Rosenberry, Bartosz Koszowski, Mishka Terplan
OBJECTIVES: To pilot-test a Phone-based Postpartum Continuing Care (PPCC) protocol developed from existing evidence-based approaches to address both postpartum smoking relapse among low-income women who quit smoking during pregnancy and postpartum smoking increase among those who had cut down. METHODS: One hundred thirty low-income pregnant women who were current or recently quit tobacco smokers were recruited at their first prenatal appointment and randomized to either a Control (standard care) or Experimental (standard care + PPCC) group...
January 18, 2018: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/29351133/using-clinical-questions-asked-by-primary-care-providers-through-econsults-to-inform-continuing-professional-development
#18
Douglas Archibald, Clare Liddy, Heather A Lochnan, Paul J Hendry, Erin J Keely
INTRODUCTION: Continuing professional development (CPD) offerings should address the educational needs of health care providers. Innovative programs, such as electronic consultations (eConsults), provide unique educational opportunities for practice-based needs assessment. The purpose of this study is to assess whether CPD offerings match the needs of physicians by coding and comparing session content to clinical questions asked through eConsults. METHODS: This study analyzes questions asked by primary care providers between July 2011 and January 2015 using a service that allows specialists to provide consultation over a secure web-based server...
January 16, 2018: Journal of Continuing Education in the Health Professions
https://www.readbyqxmd.com/read/29351122/how-to-reliably-assess-nodal-status-in-distal-pancreatectomy-for-adenocarcinoma
#19
Matthieu Faron, Hélène Vuarnesson, Jean-Marie Boher, Philippe Bachellier, Alain Sauvanet, Antonio Sa Cunha, Yves-Patrice Le Treut, Jean-Yves Mabrut, Jean-Robert Delpero, François Paye
OBJECTIVES: The optimal number of lymph nodes that need to be analyzed to reliably assess nodal status in distal pancreatectomy for adenocarcinoma is still unknown. METHODS: Two hundred seventy-eight patients who underwent distal pancreatectomy for adenocarcinoma were retrieved from a retrospective French nationwide database. The relations between the number of analyzed lymph nodes and the nodal status of the tumor were studied. The beta-binomial law was used to estimate the probability of being truly node negative depending on the number of analyzed lymph nodes...
January 18, 2018: Pancreas
https://www.readbyqxmd.com/read/29351097/effect-of-epidural-infusion-bolus-delivery-rate-on-the-duration-of-labor-analgesia-a-randomized-clinical-trial
#20
Elizabeth M S Lange, Cynthia A Wong, Paul C Fitzgerald, Wilmer F Davila, Suman Rao, Robert J McCarthy, Paloma Toledo
BACKGROUND: Programmed intermittent boluses of local anesthetic have been shown to be superior to continuous infusions for maintenance of labor analgesia. High-rate epidural boluses increase delivery pressure at the catheter orifice and may improve drug distribution in the epidural space. We hypothesized that high-rate drug delivery would improve labor analgesia and reduce the requirement for provider-administered supplemental boluses for breakthrough pain. METHODS: Nulliparous women with a singleton pregnancy at a cervical dilation of less than or equal to 5 cm at request for neuraxial analgesia were eligible for this superiority-design, double-blind, randomized controlled trial...
January 19, 2018: Anesthesiology
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