keyword
MENU ▼
Read by QxMD icon Read
search

Trending

keyword
https://www.readbyqxmd.com/read/28343330/human-papilloma-virus-hpv-infection-leads-to-the-development-of-head-and-neck-lesions-but-offers-better-prognosis-in-malignant-indian-patients
#1
Shreya Sarkar, Neyaz Alam, Jayanta Chakraborty, Jaydip Biswas, Syam Sundar Mandal, Susanta Roychoudhury, Chinmay Kumar Panda
Head and neck cancers constitute a multifactorial global disease burden and are associated with human papilloma virus (HPV) as a possible risk factor. The aim of the study is to understand the relationship between HPV and the development of head and neck lesions in Indian patients. To this end, frequency of HPV was assessed in relation to different demographic and etiological features and correlated with patient survival. The prevalence of HPV significantly increased from mild dysplastic lesions (43.6%) to head and neck squamous cell carcinoma (HNSCC) stage IV (68...
March 25, 2017: Medical Microbiology and Immunology
https://www.readbyqxmd.com/read/28343220/hemorrhagic-transformations-after-thrombectomy-risk-factors-and-clinical-relevance
#2
Johannes Kaesmacher, Mirjam Kaesmacher, Christian Maegerlein, Claus Zimmer, Alexandra S Gersing, Silke Wunderlich, Benjamin Friedrich, Tobias Boeckh-Behrens, Justus F Kleine
BACKGROUND: Hemorrhagic transformation (HT) is a major complication of acute ischemic stroke, potentially associated with clinical deterioration. We attempted to identify risk factors and evaluated clinical relevance of minor and major HTs following endovascular thrombectomy (ET) in isolated middle cerebral artery (MCA) occlusions. METHODS: This is a retrospective single-center analysis of 409 patients with isolated MCA occlusion treated with ET. Patients' and procedural characteristics, severity of HT according to the European Cooperative Acute Stroke Study criteria, and clinical outcomes were analyzed...
March 25, 2017: Cerebrovascular Diseases
https://www.readbyqxmd.com/read/28343208/legal-features-of-the-drug-advertising
#3
Vitalii M Pashkov, Andrii A Olefir, Oleksiy Y Bytyak
INTRODUCTION: In the article discribed current trends of advertising in the pharmaceutical market and foreign experience of legal regulation of these relations. As for the advertising of medicines identified it's symptoms, types, basic rules and prohibitions. Modern pharmaceutical companies can not successfully carry out economic activities without advertising. Besides we can mention some fundamental changes in society (information overload, universal access to internet, social media, freedom of movement of goods, labor and finance), also self-medication becomes more popular...
2017: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/28343180/oxygen-saturation-trends-in-normal-healthy-term-newborns-normal-vaginal-delivery-vs-elective-cesarean-section
#4
Rashi Bhargava, Madhu Mathur, Jyoti Patodia
OBJECTIVES: To study the normal oxygen saturation trends and fetomaternal correlates in healthy term newborns within 30 min of life born by normal vaginal delivery (NVD) and elective cesarean section (CS). MATERIALS AND METHODS: A cross-sectional study was conducted on 200 healthy term newborns born by NVD and elective CS at a tertiary care centre. Routine care as per the Neonatal Resuscitation Program (NRP) 2015 (Wyckoff MH, Aziz K, Escobedo MB, Kapadia VS, Kattwinkel J, Perlman JM, et al...
March 27, 2017: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/28343162/mesothelin-promoter-variants-are-associated-with-increased-soluble-mesothelin-related-peptide-levels-in-asbestos-exposed-individuals
#5
Chiara De Santi, Perla Pucci, Alessandra Bonotti, Ombretta Melaiu, Monica Cipollini, Roberto Silvestri, Veronika Vymetalkova, Elisa Barone, Elisa Paolicchi, Alda Corrado, Irene Lepori, Irene Dell'Anno, Lucia Pellè, Pavel Vodicka, Luciano Mutti, Rudy Foddis, Alfonso Cristaudo, Federica Gemignani, Stefano Landi
BACKGROUND: Soluble mesothelin-related peptide (SMRP) is a promising diagnostic biomarker for malignant pleural mesothelioma (MPM), but various confounders hinder its usefulness in surveillance programmes. We previously showed that a single nucleotide polymorphism (SNP) within the 3'untranslated region (3'UTR) of the mesothelin (MSLN) gene could affect the levels of SMRP. OBJECTIVES: To focus on SNPs located within MSLN promoter as possible critical genetic variables in determining SMRP levels...
March 25, 2017: Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28343112/the-impact-of-australian-legislative-changes-on-synthetic-cannabinoid-exposures-reported-to-the-new-south-wales-poisons-information-centre
#6
Rose Cairns, Jared A Brown, Naren Gunja, Nicholas A Buckley
BACKGROUND: The emergence of new psychoactive substances (NPS), including synthetic cannabinoid receptor agonists (SCRAs) poses novel challenges for drug regulation and public health. Misconceptions of safety and legality, coupled with the fact that NPS are undetectable on routine drugs screens contributes to their popularity. Concerns over the unpredictable toxicity and abuse potential of NPS has led to a variety of legislative responses worldwide. We wish to describe Australian trends in SCRA use, examining the effects of legislative changes on calls to Australia's largest poisons centre...
March 23, 2017: International Journal on Drug Policy
https://www.readbyqxmd.com/read/28343110/the-harder-they-fall-sex-and-race-ethnic-specific-suicide-rates-in-the-u-s-foreclosure-crisis
#7
Jason N Houle, Michael T Light
Previous work shows suicide rates increase during economic recessions, but little research has examined the extent to which the foreclosure crisis-a unique aspect of the Great Recession-has contributed to disparities in rising suicide rates by race and sex. We develop and test two competing hypotheses regarding the association between foreclosures and race by sex specific suicide rates. We link foreclosure data (RealtyTrac) and suicide data (CDC) from 174 metropolitan areas from 2005 to 2010 (1044 MSA-year observations) and find that-net of time invariant unobserved between-metro area differences, national time trends, and time-varying confounders-a rise in the foreclosure rate is associated with a marginal increase in suicide, but this main effect masks considerable heterogeneity across groups...
March 19, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28343099/source-apportionments-of-ambient-fine-particulate-matter-in-israeli-jordanian-and-palestinian-cities
#8
Jongbae Heo, Bo Wu, Ziad Abdeen, Radwan Qasrawi, Jeremy A Sarnat, Geula Sharf, Kobby Shpund, James J Schauer
This manuscript evaluates spatial and temporal variations of source contributions to ambient fine particulate matter (PM2.5) in Israeli, Jordanian, and Palestinian cities. Twenty-four hour integrated PM2.5 samples were collected every six days over a 1-year period (January to December 2007) in four cities in Israel (West Jerusalem, Eilat, Tel Aviv, and Haifa), four cities in Jordan (Amman, Aqaba, Rahma, and Zarka), and three cities in Palestine (Nablus, East Jerusalem, and Hebron). The PM2.5 samples were analyzed for major chemical components, including organic carbon and elemental carbon, ions, and metals, and the results were used in a positive matrix factorization (PMF) model to estimate source contributions to PM2...
March 23, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28343060/uv-chlorine-treatment-of-carbamazepine-transformation-products-and-their-formation-kinetics
#9
Yanheng Pan, ShuangShuang Cheng, Xin Yang, Jingyue Ren, Jingyun Fang, Chii Shang, Weihua Song, Lushi Lian, Xinran Zhang
Carbamazepine (CBZ) is one of the pharmaceuticals most frequently detected in the aqueous environment. This study investigated the transformation products when CBZ is degraded by chlorine under ultraviolet (UV) irradiation (the UV/chlorine process). Detailed pathways for the degradation of CBZ were elucidated using ultra-high performance liquid chromatography (UHPLC)-quadrupole time-of-flight mass spectrometry (QTOF-MS). CBZ is readily degraded by hydroxyl radicals (HO) and chlorine radicals (Cl) in the UV/chlorine process, and 24 transformation products were identified...
March 23, 2017: Water Research
https://www.readbyqxmd.com/read/28343037/concentration-and-sources-of-atmospheric-nitrous-acid-hono-at-an-urban-site-in-western-china
#10
Ru-Jin Huang, Lu Yang, Junji Cao, Qiyuan Wang, Xuexi Tie, Kin-Fai Ho, Zhenxing Shen, Renjian Zhang, Guohui Li, Chongshu Zhu, Ningning Zhang, Wenting Dai, Jiamao Zhou, Suixin Liu, Yang Chen, Jun Chen, Colin D O'Dowd
Highly time-resolved measurements of nitrous acid (HONO) were carried out with a highly sensitive long path absorption photometer (LOPAP) at an urban site of Xi'an in Western China from 24 July to 6 August 2015 to investigate the atmospheric variations, sources, and formation pathways of HONO. The concentrations of HONO vary from 0.02 to 4.3ppbv with an average of 1.12ppbv for the entire measurement period. The variation trends of HONO and NO2 are very similar and positively correlated which, together with the similar diurnal profiles of HONO/NO2 ratio and HONO, suggest the importance of heterogeneous conversion of HONO from NO2...
March 23, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28342994/persistent-organic-pollutants-pops-in-the-atmosphere-of-coastal-areas-of-the-ross-sea-antarctica-indications-for-long-term-downward-trends
#11
Karla Pozo, Tania Martellini, Simonetta Corsolini, Tom Harner, Victor Estellano, Petr Kukučka, Marie D Mulder, Gerhard Lammel, Alessandra Cincinelli
Passive air samplers were used to evaluate long-term trends and spatial distribution of trace organic compounds in Antarctica. Duplicate PUF disk samplers were deployed at six automatic weather stations in the coastal area of the Ross sea (East Antarctica), between December 2010 and January 2011, during the XXVI Italian Scientific Research Expedition. Among the investigated persistent organic compounds, Hexachlorobenzene was the most abundant, with air concentrations ranging from 0.8 to 50 pg m(-3). In general, the following decreasing concentration order was found for the air samples analyzed: HCB > PeCB > PCBs > DDTs > HCHs...
February 27, 2017: Chemosphere
https://www.readbyqxmd.com/read/28342863/disturbed-tryptophan-metabolism-correlating-to-progression-and-metastasis-of-esophageal-squamous-cell-carcinoma
#12
Jing Cheng, Hai Jin, Xiaobei Hou, Jie Lv, Xianfu Gao, Guangyong Zheng
Esophageal squamous cell carcinoma (ESCC) is one of the most frequent malignancies worldwide. Lymph node metastasis is the leading cause of death in ESCC patients. To identify early diagnostic and prognostic biomarkers of ESCC and elucidate underlying pathogenesis of the disease, a targeted metabolomics strategy based on liquid chromatography combined with tandem mass spectrometry was applied to explore tryptophan metabolism between ESCC patients, metastatic ESCC patients (mESCC), and healthy controls. Statistical analysis on metabolite expression abundance and compound concentration ratio was conducted to discriminate patients from healthy controls...
March 23, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/28342801/geographic-disparities-of-pneumonia-specific-under-5-mortality-rates-in-mainland-china-from-1996-to-2015-a-population-based-study
#13
Leni Kang, Chunhua He, Lei Miao, Juan Liang, Jun Zhu, Xiaohong Li, Qi Li, Yanping Wang
OBJECTIVES: This study aims to investigate the disparities of pneumonia-specific under-5 mortality rate (PU5MR) among and within three geographic regions in Mainland China from 1996 to 2015. METHODS: We used data from China's Under-5 Child Mortality Surveillance System (U5CMSS) and grouped the study period by every two years. The Cochran-Armitage trend test and Cochran-Mantel-Haenszel test were used to assess trends and differences in PU5MR among and within geographic regions...
March 22, 2017: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/28342786/pharmaceutical-solvates-hydrates-and-amorphous-forms
#14
REVIEW
Anne Marie Healy, Zelalem Ayenew Worku, Dinesh Kumar, Atif M Madi
Active pharmaceutical ingredients (APIs) may exist in various solid forms, which can lead to differences in the intermolecular interactions, affecting the internal energy and enthalpy, and the degree of disorder, affecting the entropy. Differences in solid forms often lead to differences in thermodynamic parameters and physicochemical properties for example solubility, dissolution rate, stability and mechanical properties of APIs and excipients. Hence, solid forms of APIs play a vital role in drug discovery and development in the context of optimization of bioavailability, filing intellectual property rights and developing suitable manufacturing methods...
March 22, 2017: Advanced Drug Delivery Reviews
https://www.readbyqxmd.com/read/28342754/dietary-supplementation-of-thiamine-and-pyridoxine-loaded-vanillic-acid-grafted-chitosan-microspheres-enhances-growth-performance-metabolic-and-immune-responses-in-experimental-rats
#15
C S Tejpal, N S Chatterjee, K Elavarasan, R G K Lekshmi, R Anandan, K K Asha, B Ganesan, S Mathew, C N Ravishankar
In the present investigation, the effect of dietary supplementation of thiamine and pyridoxine loaded vanillic acid-grafted chitosan microspheres (TPVGC) on growth, metabolic and immune responses in Wistar strain albino rats was studied. Eight experimental groups, namely four groups each for male and female rats were fed with 0, 0.4, 0.8 and 1.6% of TPVGC in the diet. At the end of 45days feeding trials, both male and female rats supplemented with TPVGC had higher weight gain % and specific growth rate than the control groups...
March 22, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28342721/four-year-follow-up-of-the-changes-in-anterior-segment-after-phakic-collamer-lens-icl-implantation
#16
Yuanyuan Lu, Na Yang, Xuedong Li, Jun Kong
PURPOSE: To assess the changes and relationship in central vaulting, flare intensity and crystalline lens thickness during a follow-up period of 4 years after Implantable Collamer Lens (ICL) implantation in eyes with high myopia. DESIGN: Retrospective observational study. METHODS: 98 eyes of 50 patients were followed up with routine measurements of central vaulting, crystalline lens thickness, endothelial cell density and aqueous flare postoperatively...
March 22, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28342704/trends-in-the-presentation-surgical-treatment-and-outcomes-of-tethered-cord-syndrome-a-nationwide-study-from-2001-to-2010
#17
Cyrus M Jalai, Charles Wang, Bryan J Marascalchi, Samantha R Horn, Gregory W Poorman, Olivia J Bono, Anthony K Frempong-Boadu, Peter G Passias
OBJECTIVE: This is a nationwide query into surgical management techniques for tethered cord syndrome, focusing on patient demographic, hospital characteristics, and treatment outcomes. Our hypothesis is that detethering vs. fusion for TCS results in different in-hospital complications. MATERIALS AND METHODS: Retrospective review of the Nationwide Inpatient Sample 2001-2010. Inclusion: TCS discharges undergoing detethering or fusion. Sub-analysis compared TCS cases by age (pediatric [≤9years] vs...
March 22, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28342688/in-hospital-mortality-30-day-readmission-and-length-of-hospital-stay-after-surgery-for-primary-colorectal-cancer-a-national-population-based-study
#18
S Pucciarelli, M Zorzi, N Gennaro, G Gagliardi, A Restivo, M Saugo, A Barina, M Rugge, M Zuin, I Maretto, D Nitti
INTRODUCTION: The simultaneous assessment of multiple indicators for quality of care is essential for comparisons of performance between hospitals and health care systems. The aim of this study was to assess the rates of in-hospital mortality and 30-day readmission and length of hospital stay (LOS) in patients who underwent surgical procedures for colorectal cancer between 2005 and 2014 in Italy. METHODS: All patients in the National Italian Hospital Discharge Dataset who underwent a surgical procedure for colorectal cancer during the study period were included...
March 16, 2017: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28342662/use-of-brca-mutation-test-in-the-u-s-2004-2014
#19
Fangjian Guo, Jacqueline M Hirth, Yu-Li Lin, Gwyn Richardson, Lyuba Levine, Abbey B Berenson, Yong-Fang Kuo
INTRODUCTION: BRCA mutation testing has been used for screening women at high risk of breast and ovarian cancer and for selecting the best treatment for those with breast cancer. To optimize the infrastructure and medical resources allocation for genetic testing, it is important to understand the use of BRCA mutation testing in the U.S. health system. METHODS: This retrospective cohort study included 53,254 adult women with insurance claims for BRCA mutation testing between 2004 and 2014 from Clinformatics(TM) Data Mart Database...
March 18, 2017: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28342661/climate-change-and-human-infectious-diseases-a-synthesis-of-research-findings-from-global-and-spatio-temporal-perspectives
#20
Lu Liang, Peng Gong
The life cycles and transmission of most infectious agents are inextricably linked with climate. In spite of a growing level of interest and progress in determining climate change effects on infectious disease, the debate on the potential health outcomes remains polarizing, which is partly attributable to the varying effects of climate change, different types of pathogen-host systems, and spatio-temporal scales. We summarize the published evidence and show that over the past few decades, the reported negative or uncertain responses of infectious diseases to climate change has been growing...
March 22, 2017: Environment International
keyword
keyword
12213
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"