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https://www.readbyqxmd.com/read/28646801/the-effects-of-exposure-to-low-frequency-electromagnetic-fields-on-male-fertility
#1
Mahsa Darbandi, Sara Darbandi, Ashok Agarwal, Ralf Henkle, Mohammad Reza Sadeghi
Context • People are increasingly exposed to low frequency (LF) electromagnetic fields (EMFs), mainly from electricity distribution networks and electronic devices. Critics of this widespread exposure believe that it can have detrimental effects on the human body. On the other hand, many in vivo and in vitro studies have claimed that low frequency electromagnetic therapy can function as a form of alternative medicine and that therapists can treat disease by applying electromagnetic radiation or pulsed EMFs to the body or cells...
June 23, 2017: Alternative Therapies in Health and Medicine
https://www.readbyqxmd.com/read/28636944/transduction-of-repetitive-mechanical-stimuli-by-piezo1-and-piezo2-ion-channels
#2
Amanda H Lewis, Alisa F Cui, Malcolm F McDonald, Jörg Grandl
Several cell types experience repetitive mechanical stimuli, including vein endothelial cells during pulsating blood flow, inner ear hair cells upon sound exposure, and skin cells and their innervating dorsal root ganglion (DRG) neurons when sweeping across a textured surface or touching a vibrating object. While mechanosensitive Piezo ion channels have been clearly implicated in sensing static touch, their roles in transducing repetitive stimulations are less clear. Here, we perform electrophysiological recordings of heterologously expressed mouse Piezo1 and Piezo2 responding to repetitive mechanical stimulations...
June 20, 2017: Cell Reports
https://www.readbyqxmd.com/read/28628659/wave-intensity-of-aortic-root-pressure-as-diagnostic-marker-of-left-ventricular-systolic-dysfunction
#3
Bernhard Hametner, Stephanie Parragh, Thomas Weber, Siegfried Wassertheurer
BACKGROUND: Systolic left ventricular function strongly influences the blood pressure waveform. Therefore, pressure-derived parameters might potentially be used as non-invasive, diagnostic markers of left ventricular impairment. The aim of this study was to investigate the performance of pressure-based parameters in combination with electrocardiography (ECG) for the detection of left ventricular systolic dysfunction defined as severely reduced ejection fraction (EF). METHODS AND RESULTS: Two populations, each comprising patients with reduced EF and pressure-matched controls, were included for the main analysis (51/102 patients) and model testing (44/88 patients)...
2017: PloS One
https://www.readbyqxmd.com/read/28622745/sex-differences-in-vascular-stiffness-and-relationship-to-the-risk-of-renal-functional-decline-in-patients-with-type-2-diabetes
#4
Kenneth A Earle, Lauren Ng, Sarah White, Karima Zitouni
BACKGROUND: Recent data suggest that the higher risk of end-stage renal disease in women compared with men is associated with waist circumference. We investigated whether vascular stiffness which is linked to visceral fat accumulation is gender specific and associated with a loss in renal function. METHODS: We studied 166 patients with type 2 diabetes at high risk of progressive renal disease. A vascular stiffness index was derived from measurement of the peripheral arterial pulse waveform using infrared finger photoplethysmography...
July 2017: Diabetes & Vascular Disease Research
https://www.readbyqxmd.com/read/28620319/vascular-endothelial-growth-factor-b-induces-a-distinct-electrophysiological-phenotype-in-mouse-heart
#5
Nikolay Naumenko, Jenni Huusko, Tomi Tuomainen, Jussi T Koivumäki, Mari Merentie, Erika Gurzeler, Kari Alitalo, Riikka Kivelä, Seppo Ylä-Herttuala, Pasi Tavi
Vascular endothelial growth factor B (VEGF-B) is a potent mediator of vascular, metabolic, growth, and stress responses in the heart, but the effects on cardiac muscle and cardiomyocyte function are not known. The purpose of this study was to assess the effects of VEGF-B on the energy metabolism, contractile, and electrophysiological properties of mouse cardiac muscle and cardiac muscle cells. In vivo and ex vivo analysis of cardiac-specific VEGF-B TG mice indicated that the contractile function of the TG hearts was normal...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28614281/transcranial-motor-evoked-potential-alarm-criteria-to-predict-foot-drop-injury-during-lumbosacral-surgery
#6
Arvydas Tamkus, Kent S Rice, Gregory Hoffman
STUDY DESIGN: Retrospective cohort analysis. OBJECTIVE: This study aims to investigate whether waveform alterations in transcranial motor evoked potentials (TCMEP) can reliably predict postoperative foot drop. SUMMARY OF BACKGROUND DATA: Nerve injury leading to foot drop is a potential complication of lumbosacral surgery. Very limited data exist on the use of intraoperative TcMEPs to identify iatrogenic foot drop. METHODS: We retrospectively reviewed neuromonitoring data from 130 consecutive spine surgeries with instrumentation involving L4-S1...
June 13, 2017: Spine
https://www.readbyqxmd.com/read/28571131/systemic-and-local-effects-of-warm-oxygen-exposure-to-the-lower-extremities-in-healthy-volunteers
#7
Vidya Sunil Joshi, Sunil Subhash Joshi, Maruthy
INTRODUCTION: Warmth to the extremity is known to improve the cutaneous blood flow and tissue perfusion. Oxygen is essential for healing of chronic wounds. Topical oxygen therapy has become standard therapy in management of lower extremity wounds. A combination of local heat and oxygen is likely to be beneficial in many clinical scenarios of non-healing wounds without any systemic effects. AIM: To evaluate the local and systemic effects of the exposure of extremity to warm oxygen in healthy volunteers...
April 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28566465/the-stochastic-nature-of-action-potential-backpropagation-in-apical-tuft-dendrites
#8
Shaina M Short, Katerina D Oikonomou, Wen-Liang L Zhou, Corey D Acker, Marko A Popovic, Dejan Zecevic, Srdjan D Antic
In cortical pyramidal neurons, backpropagating action potentials (bAPs) supply Ca(2+) to synaptic contacts on dendrites. To determine whether the efficacy of AP backpropagation into apical tuft dendrites is stable over time, we performed dendritic Ca(2+) and voltage imaging in rat brain slices. We found that the amplitude of bAP-Ca(2+) in apical tuft branches was unstable, as it varied from trial to trial (termed "bAP-Ca(2+) flickering"). Small perturbations in dendritic physiology, such as spontaneous synaptic inputs, channel inactivation, or temperature-induced changes in channel kinetics, can cause bAP flickering...
May 31, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/28559807/eeg-and-eye-tracking-signatures-of-target-encoding-during-structured-visual-search
#9
Anne-Marie Brouwer, Maarten A Hogervorst, Bob Oudejans, Anthony J Ries, Jonathan Touryan
EEG and eye tracking variables are potential sources of information about the underlying processes of target detection and storage during visual search. Fixation duration, pupil size and event related potentials (ERPs) locked to the onset of fixation or saccade (saccade-related potentials, SRPs) have been reported to differ dependent on whether a target or a non-target is currently fixated. Here we focus on the question of whether these variables also differ between targets that are subsequently reported (hits) and targets that are not (misses)...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28528787/inspiratory-phonation-in-baby-voice
#10
Kathleen Wermke, Asin Ahmad Haschemi, Volker Hesse, Michael P Robb
OBJECTIVE: This study aimed to evaluate the developmental occurrence of inspiratory phonations (IPs) in the spontaneous cries of healthy infants across the first 10 weeks of life. STUDY DESIGN: This is a populational retrospective study. PARTICIPANTS: The spontaneous crying of 17 healthy infants (10 were male) was retrospectively investigated. MATERIALS AND METHODS: Sound files of spontaneously uttered cries that were repeatedly recorded once per week for across the first 10 weeks of life were retrospectively analyzed...
May 18, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/28520951/non-selective-his-bundle-pacing-with-a-biphasic-waveform-enhancing-septal-resynchronization
#11
Daniel F Ortega, Luis D Barja, Emilio Logarzo, Nicolas Mangani, Analia Paolucci, Maria P Bonomini
Aims: His bundle pacing has shown to prevent detrimental effects from right ventricular apical pacing (RVA) and proved to resynchronize many conduction disturbances cases. However, the extent of His bundle pacing resynchronization is limited. An optimized stimulation waveform could expand this limit when implemented in His bundle pacing sets. In this work, we temporarily implemented RVA and Non-selective His bundle pacing with a biphasic anodal-first waveform (AF-nHB) and compared their effects against sinus rhythm (SR)...
May 17, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28497774/evaluation-of-respiratory-and-postural-induced-changes-on-the-ballistocardiogram-signal-by-time-warping-averaging
#12
Alba Martin-Yebra, Federica Landreani, Claudia Casellato, Esteban Enrique Pavan, Pierre-François Migeotte, Carlo Frigo, Juan Martinez Cortes, Enrico Caiani
OBJECTIVE: The aim of this work was to evaluate the potential changes in the ballistocardiogram (BCG) signal induced by different respiratory patterns and posture, by using the dynamic time warping (DTW) technique. APPROACH: BCG signals were recorded in a group of 20 healthy volunteers, simultaneously to the ECG. Two recordings, one in supine (SUP) and one in standing (ST) position, including spontaneous breathing, two 1-minute apneas (at full and empty-lungs, respectively) and 30s of Valsalva, were analyzed...
May 12, 2017: Physiological Measurement
https://www.readbyqxmd.com/read/28485823/effects-of-aphidius-gifuensis-on-the-feeding-behavior-and-potato-virus-y-transmission-ability-of-myzus-persicae
#13
Ying-Qin He, Yong-Qiang Zhang, Juan-Ni Chen, Wen-Long Chen, Xian-Yi Zeng, Hai-Tao Chen, Wei Ding
The stylet penetration behavior of aphids when feeding on plants is associated with virus acquisition and inoculation. Aphidius gifuensis (Ashmead) is a primary endoparasitoid of Myzus persicae (Sulzer) which is the most efficient vector of plant viruses. Information about the effects of parasitoid on aphid and virus transmission can provide an essential foundation for designing effective biological control strategies. This study aimed to investigate the effects of A. gifuensis on the feeding behavior and Potato virus Y (PVY) transmission ability of M...
May 9, 2017: Insect Science
https://www.readbyqxmd.com/read/28475545/effects-of-stimulus-duration-on-event-related-potentials-recorded-from-cochlear-implant-users
#14
Alessandro Presacco, Hamish Innes-Brown, Matthew J Goupell, Samira Anderson
OBJECTIVES: Several studies have investigated the feasibility of using electrophysiology as an objective tool to efficiently map cochlear implants. A pervasive problem when measuring event-related potentials is the need to remove the direct-current (DC) artifact produced by the cochlear implant. Here, we describe how DC artifact removal can corrupt the response waveform and how the appropriate choice of stimulus duration may minimize this corruption. DESIGN: Event-related potentials were recorded to a synthesized vowel /a/ with a 170- or 400-ms duration...
May 4, 2017: Ear and Hearing
https://www.readbyqxmd.com/read/28467509/laryngeal-evidence-for-the-first-and-second-passaggio-in-professionally-trained-sopranos
#15
Matthias Echternach, Fabian Burk, Marie Köberlein, Andreas Selamtzis, Michael Döllinger, Michael Burdumy, Bernhard Richter, Christian Thomas Herbst
INTRODUCTION: Due to a lack of empirical data, the current understanding of the laryngeal mechanics in the passaggio regions (i.e., the fundamental frequency ranges where vocal registration events usually occur) of the female singing voice is still limited. MATERIAL AND METHODS: In this study the first and second passaggio regions of 10 professionally trained female classical soprano singers were analyzed. The sopranos performed pitch glides from A3 (ƒo = 220 Hz) to A4 (ƒo = 440 Hz) and from A4 (ƒo = 440 Hz) to A5 (ƒo = 880 Hz) on the vowel [iː]...
2017: PloS One
https://www.readbyqxmd.com/read/28459692/a-128-channel-fpga-based-real-time-spike-sorting-bidirectional-closed-loop-neural-interface-system
#16
Jongkil Park, Gookhwa Kim, Sang-Don Jung
A multichannel neural interface system is an important tool for various types of neuroscientific studies. For the electrical interface with a biological system, high-precision highspeed data recording and various types of stimulation capability are required. In addition, real-time signal processing is an important feature in the implementation of a real-time closed-loop system without unwanted substantial delay for feedback stimulation. Online spike sorting, the process of assigning neural spikes to an identified group of neurons or clusters, is a necessary step to make a closed-loop path in real time, but massive memory-space requirements commonly limit hardware implementations...
April 24, 2017: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://www.readbyqxmd.com/read/28458554/patient-characteristics-associated-with-false-arrhythmia-alarms-in-intensive-care
#17
Patricia R Harris, Jessica K Zègre-Hemsey, Daniel Schindler, Yong Bai, Michele M Pelter, Xiao Hu
INTRODUCTION: A high rate of false arrhythmia alarms in the intensive care unit (ICU) leads to alarm fatigue, the condition of desensitization and potentially inappropriate silencing of alarms due to frequent invalid and nonactionable alarms, often referred to as false alarms. OBJECTIVE: The aim of this study was to identify patient characteristics, such as gender, age, body mass index, and diagnosis associated with frequent false arrhythmia alarms in the ICU. METHODS: This descriptive, observational study prospectively enrolled patients who were consecutively admitted to one of five adult ICUs (77 beds) at an urban medical center over a period of 31 days in 2013...
2017: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/28436812/retrospective-waveform-analysis-of-transcranial-motor-evoked-potentials-mep-to-identify-early-predictors-of-impending-motor-deficits-in-spinal-surgeries
#18
Scheherazade Le, Viet Nguyen, Alexander C Ekwueme, S Charles Cho, Leslie Lee, Jaime López
PURPOSE: Although there are guidelines analyzing transcranial motor evoked potentials (MEP) waveform criteria, they vary widely and are not applied universally during intraoperative neurophysiologic monitoring (IONM). The objective is to generate hypotheses to identify early and reliable MEP waveform characteristics prior to complete loss of MEP to predict impending motor spinal cord injuries during spinal surgeries. The ultimate goal is to enhance real-time feedback to prevent injury or detect reversible spinal cord damage...
2017: Neurodiagnostic Journal
https://www.readbyqxmd.com/read/28377112/the-assessment-of-electrophysiological-activity-in-human-induced-pluripotent-stem-cell-derived-cardiomyocytes-exposed-to-dimethyl-sulfoxide-and-ethanol-by-manual-patch-clamp-and-multi-electrode-array-system
#19
Soo-Wang Hyun, Bo-Ram Kim, Sung-Ae Hyun, Joung-Wook Seo
INTRODUCTION: Recently, electrophysiological activity has been effectively measured in human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) to predict drug-induced arrhythmia. Dimethyl sulfoxide (DMSO) and ethanol have been used as diluting agents in many experiments. However, the maximum DMSO and ethanol concentrations that can be effectively used in the measurement of electrophysiological parameters in hiPSC-CMs-based patch clamp and multi-electrode array (MEA) have not been fully elucidated...
April 1, 2017: Journal of Pharmacological and Toxicological Methods
https://www.readbyqxmd.com/read/28374072/outcomes-following-cryoballoon-ablation-for-atrial-fibrillation-guided-by-pressure-waveform-monitoring-without-the-routine-use-of-pulmonary-venography
#20
Akshit Sharma, Jashdeep Dhoot, Jingyan Wang, Philip Jones, Sanjaya Gupta, Alan P Wimmer
PURPOSE: Pressure waveform analysis has the potential for facilitated assessment of pulmonary vein occlusion during cryoballoon ablation for atrial fibrillation. Data on clinical outcomes using this method are lacking. We sought to validate through clinical outcomes the use of pressure waveform analysis as the primary method of determining pulmonary vein occlusion during cryoballoon ablation. METHODS: A study was performed of 122 consecutive patients with atrial fibrillation (85% paroxysmal) undergoing cryoballoon ablation from May 2014 through July 2015 at a single institution using pressure waveform analysis as the primary method of assessing pulmonary vein occlusion...
June 2017: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
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