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https://www.readbyqxmd.com/read/29684546/connubial-bliss-or-distress-transcatheter-mitral-valve-implantation-with-mechanical-aortic-prostheses
#1
EDITORIAL
Mohamad Alkhouli, Vinay Badhwar
No abstract text is available yet for this article.
April 20, 2018: Seminars in Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29684164/acute-kidney-injury-after-aortic-valve-replacement-in-a-nationally-representative-cohort-in-the-usa
#2
Nilay Kumar, Neetika Garg
Background: Randomized trials have consistently shown lower rates of acute kidney injury (AKI) with transcatheter aortic valve replacement (TAVR) compared with surgical aortic valve replacement (SAVR). Comparative rates of AKI for TAVR versus SAVR, and predictors and prognostic implications of AKI after aortic valve replacement (AVR) have not been well studied in nationally representative real-world data. Objectives: First, to compare rates of AKI and dialysis requiring AKI in TAVR versus SAVR...
April 18, 2018: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/29684119/aortic-stiffness-in-adolescent-turner-and-marfan-syndrome-patients
#3
Michal Schäfer, Lorna P Browne, Uyen Truong, James J Jaggers, Max B Mitchell, Ladonna Malone, Gareth Morgan, Kathryn Chatfield, Daniel McLennan, Harma Turbendian, Danial Vargas, Brian Fonseca, Michael DiMaria, Anar Shah, Margaret P Ivy, Alex J Barker, Kendall S Hunter, Neil Wilson, D Dunbar Ivy, David N Campbell
OBJECTIVES: Turner syndrome (TS) and Marfan syndrome (MFS) are partially characterized by aortopathies with a risk of developing severe aortic dilation, stiffness and consequent dissection and aneurysm formation. The incidence of a bicuspid aortic valve (BAV) is also increased in TS. We investigated aortic stiffness in teenage TS and MFS patients and evaluated to what degree stiffness in TS patients is augmented by the presence of a BAV. METHODS: Fifty-seven patients with TS (n = 37) and MFS (n = 20), as well as 22 controls with similar age and size distribution underwent evaluation of thoracic aortic stiffness using phase-contrast magnetic resonance imaging...
April 19, 2018: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29683812/current-trends-in-aortic-root-surgery-the-mini-bentall-approach
#4
Djamila Abjigitova, Georgia Panagopoulos, Oleg Orlov, Vishal Shah, Konstadinos A Plestis
OBJECTIVE: The mini-sternotomy approach is becoming a widespread technique for aortic valve surgery. However, its safety for aortic root replacement has yet to be established. The aim of the present study was to compare the operative outcomes of patients who underwent aortic root replacement via upper mini-sternotomy (mini-Bentall) to patients who underwent Bentall procedure via median sternotomy (full-sternotomy Bentall). METHODS: Between November 1998 and November 2016, 91 consecutive patients underwent full-sternotomy Bentall procedure and 26 patients underwent mini-Bentall procedure...
April 20, 2018: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
https://www.readbyqxmd.com/read/29682470/aortic-valve-insufficiency-in-aortic-root-aneurysms-consider-every-valve-for-repair
#5
REVIEW
Talal Al-Atassi, Munir Boodhwani
Aortic valve (AV) preservation and repair is emerging as an attractive alternative to AV replacement in younger patients with aortic insufficiency (AI) and aortic root aneurysms. AV repair mitigates some of the risks associated with prosthetic valves. More centers are reporting the safety of AV preservation and repair and favorable short- and long-term outcomes. However, further work is needed to improve long-term repair durability and dissemination of knowledge and technique to make AV repair the gold standard in this patient population...
2018: Journal of Visualized Surgery
https://www.readbyqxmd.com/read/29682454/awake-transcatheter-aortic-valve-replacement-an-anesthesiologist-s-perspective
#6
Jiapeng Huang, Sheng Wang, Jiakai Lu
Transcatheter aortic replacement has become the standard of care for patients with severe aortic valve stenosis. With advancement of technologies, this technique has become much safer and simpler. Both general anesthesia (GA) and monitored anesthesia care (MAC) have been provided for transcatheter aortic valve replacement (TAVR). MAC or awake transcatheter valve replacement was shown to carry similar clinical outcomes with significantly reduced length of stay. We reviewed the literature and presented our practical minimalist anesthesia approach to awake TAVR...
2018: Journal of Visualized Surgery
https://www.readbyqxmd.com/read/29681960/first-uses-of-haart-300-rings-for-aortic-valve-repair-in-poland-4-case-studies
#7
Jacek H Juściński, Andrzej Koprowski, Magdalena Kołaczkowska, Maciej M Kowalik, Jan A Rogowski, James S Rankin
Introduction: Aortic valve reconstructions using geometric annuloplasty rings HAART 300/200 open new era in aortic valve surgery. The HAART technology resizes, reshapes, stabilizes and simplifies aortic valve repair. The HAART aortic repair rings are designed to be implanted directly into aortic annulus (under aortic valve leaflets). Aim: We present first in Poland 4 cases of aortic valve reconstructions using geometric annuloplasty rings HAART 300. Material and methods: Two patients had type IA aortic insufficiency (due to El-Khoury classification) - they were treated by HAART 300 ring insertion and ascending aorta prosthesis implantation...
March 2018: Kardiochirurgia i Torakochirurgia Polska, Polish Journal of Cardio-Thoracic Surgery
https://www.readbyqxmd.com/read/29681570/single-femoral-venous-drainage-versus-both-vena-cava-drainage-in-isolated-repeat-tricuspid-valve-surgery
#8
Runsheng Peng, Hui Shi, Jun Ba, Chunsheng Wang
To assess the potential advantages of minimally invasive surgery using a single femoral venous drainage method versus femoral venous and superior vena cava or jugular venous drainage method during repeat tricuspid valve surgery.From January 2010 to December 2016, 50 repeat tricuspid valve procedures were performed using a minimally invasive approach without aortic cross-clamping at our institution. The arterial cannula was inserted into the femoral artery, and at the same time, the venous cannula was placed in the femoral vein in 28 patients (FV group) during cardiopulmonary bypass (CPB)...
April 20, 2018: International Heart Journal
https://www.readbyqxmd.com/read/29681546/educational-series-in-congenital-heart-disease-congenital-left-sided-heart-obstruction
#9
REVIEW
Michelle Carr, Stephanie Curtis, Jan Marek
Congenital obstruction of the left ventricular outflow tract remains a significant problem and multilevel obstruction can often coexist. Obstruction can take several morphological forms and may involve the subvalvar, valvar or supravalvar portion of the aortic valve complex. Congenital valvar stenosis presenting in the neonatal period represents a spectrum of disorders ranging from the hypoplastic left heart syndrome to almost normal hearts. Treatment options vary dependent on the severity of the left ventricular outflow tract obstruction (LVOTO) and the variable degree of left ventricular hypoplasia as well as the associated lesions such as arch hypoplasia and coarctation...
June 2018: Echo Research and Practice
https://www.readbyqxmd.com/read/29681408/manta-versus-proglide-vascular-closure-devices-in-transfemoral-transcatheter-aortic-valve-implantation
#10
Fausto Biancari, Hannu Romppanen, Mikko Savontaus, Antti Siljander, Timo Mäkikallio, Olli-Pekka Piira, Jarkko Piuhola, Viivi Vilkki, Antti Ylitalo, Tuija Vasankari, Juhani K E Airaksinen, Matti Niemelä
BACKGROUND: The MANTA system is a novel vascular closure device (VCD) and its safety and efficacy were compared to the ProGlide VCD in patients undergoing transfemoral transcatheter aortic valve implantation (TAVI). METHODS: This is a retrospective study including 222 patients who underwent transfemoral TAVI at three Finnish University Hospitals. The MANTA VCD was used in 107 patients and their outcome was compared with that of 115 patients in whom the arterial access was closed with the ProGlide VCD...
April 14, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29681152/highly-selective-and-potent-ecto-nucleotide-pyro%C3%A2-phosphatase-1-npp1-inhibitors-based-on-uridine-5-p%C3%AE-%C3%AE-dithiophosphate-analogues
#11
Vadim Zelikman, Julie Pelletier, Luba Simhaev, Aviad Sela, Fernand-Pierre Gendron, Guillaume Arguin, Hanoch Senderowitz, Jean Sévigny, Bilha Fischer
Ecto-nucleotide pyro¬phosphatase/phosphodiesterase-1 (NPP1) hydrolyzes phospho¬diester bonds of nucleotides such as ATP, resulting mainly in the formation of AMP and pyrophosphate. NPP1 activity plays a deleterious function in calcified aortic valve disease and calcium pyrophosphate deposition disease. Thus, inhibitors of NPP1 represent a medical need. We developed novel NPP1 inhibitors based on uridine 5'-Pα,α-di-thiophosphate analogues, 9-12. All these analogues potently inhibited hNPP1 (80-100% inhibition) at 100 µM, with no, or minimal, inhibition of NPP3 and other ectonucleotidases (NTPDase1,2,3,8)...
April 22, 2018: Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/29680865/comparison-of-midterm-outcomes-of-transcatheter-aortic-valve-implantation-in-patients-with-and-without-previous-coronary-artery-bypass-grafting
#12
Hideyuki Kawashima, Yusuke Watanabe, Ken Kozuma, Akihisa Kataoka, Makoto Nakashima, Hirofumi Hioki, Fukuko Nagura, Yugo Nara, Shinichi Shirai, Norio Tada, Motoharu Araki, Toru Naganuma, Futoshi Yamanaka, Hiroshi Ueno, Minoru Tabata, Kazuki Mizutani, Akihiro Higashimori, Kensuke Takagi, Masanori Yamamoto, Kentaro Hayashida
The midterm safety and feasibility of transcatheter aortic valve implantation (TAVI) for patients with a history of coronary artery bypass graft (CABG) and high operative risk are unclear. This study compared the midterm outcomes of patients undergoing TAVI with or without previous CABG surgery. Between October 2013 and July 2016, 1,613 patients underwent TAVI according to the Optimized CathEter vAlvular iNtervention (OCEAN)-TAVI registry (previous CABG: n = 120; no previous CABG: n = 1493). The propensity score comprised the variables of the Society of Thoracic Surgeons Score, previous myocardial infarction, peripheral artery disease, chronic kidney disease > stage 2 (estimated glomerular filtration rate < 60 mL/min/1...
April 21, 2018: Heart and Vessels
https://www.readbyqxmd.com/read/29680713/bicuspid-aortic-valve-aortopathy-in-the-era-of-fake-news-a-clinician-s-perspective-on-the-truth
#13
EDITORIAL
Hector I Michelena
No abstract text is available yet for this article.
March 29, 2018: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29680341/pulmonary-hypertension-in-patients-with-severe-aortic-stenosis-prognostic-impact-after-transcatheter-aortic-valve-replacement-pulmonary-hypertension-in-patients-undergoing-tavr
#14
Brunilda Alushi, Frederik Beckhoff, David Leistner, Marcus Franz, Markus Reinthaler, Barbara E Stähli, Andreas Morguet, Hans R Figulla, Torsten Doenst, Francesco Maisano, Volkmar Falk, Ulf Landmesser, Alexander Lauten
OBJECTIVES: The authors investigated the development of pulmonary hypertension (PH), predictors of PH regression, and its prognostic impact on short, mid-, and long-term outcomes in patients undergoing transcatheter aortic valve replacement (TAVR) for severe aortic stenosis (AS). BACKGROUND: PH represents a common finding in patients with AS. Although TAVR is frequently associated with regression of PH, the predictors of reversible PH and its prognostic significance remain uncertain...
April 13, 2018: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29680217/delayed-left-main-narrowing-from-the-native-left-aortic-valve-leaflet-after-transcatheter-aortic-valve-replacement-with-the-lotus-valve-a-successful-intervention-for-a-novel-complication
#15
Matthew S Glassy, Jeffrey A Southard, Benjamin R Stripe, Reginald I Low
No abstract text is available yet for this article.
April 12, 2018: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29680215/in-vivo-stent-frame-infolding-of-a-self-expanding-transcatheter-aortic-valve-after-resheathing
#16
Mohammad Abdelghani, Ahmed El Ghalban, Martin Landt, Gert Richardt, Mohamed Abdel-Wahab
No abstract text is available yet for this article.
April 12, 2018: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29680171/impact-of-balloon-predilatation-on-hemodynamics-and-outcomes-after-transcatheter-aortic-valve-implantation-with-the-self-expanding-corevalve-prosthesis
#17
Toby Rogers, Ron Waksman, J Kevin Harrison, G Michael Deeb, Angie Q Zhang, James B Hermiller, Jeffrey J Popma, Michael J Reardon
The impact of predilatation (Pre-Dil) on prosthesis hemodynamics and clinical outcomes of subjects who underwent transcatheter aortic valve implantation (TAVI) with a self-expanding prosthesis remains unclear. Two thousand seven hundred twenty-one subjects from the extreme- and high-risk CoreValve Continued Access Study (CAS) were included in the analysis. Subjects who underwent Pre-Dil before TAVI were compared with subjects who underwent TAVI without Pre-Dil. Clinical outcomes included death, stroke, myocardial infarction, acute kidney injury, and new permanent pacemaker implantation...
March 1, 2018: American Journal of Cardiology
https://www.readbyqxmd.com/read/29679990/three-dimensional-echocardiographic-evaluation-of-ebstein-s-anomaly-of-the-tricuspid-valve-in-a-patient-with-hypoplastic-left-heart-syndrome
#18
Courtney Cassidy, Max B Mitchell, Pei-Ni Jone
We report three-dimensional imaging of a rare finding of Ebstein's anomaly of the tricuspid valve in a patient with hypoplastic left heart syndrome, which has been previously reported only by two-dimensional echocardiography. A fetal echocardiogram was performed at 19 weeks that showed a moderately hypoplastic left ventricle, severely hypoplastic mitral valve, a severely hypoplastic aortic valve, and a dysplastic tricuspid valve. Post Caesarean delivery at 40 weeks of gestation, a transthoracic echocardiogram confirmed the findings seen on the fetal echocardiogram...
April 22, 2018: Cardiology in the Young
https://www.readbyqxmd.com/read/29679571/metformin-ameliorates-tgf-%C3%AE-1-induced-osteoblastic-differentiation-of-human-aortic-valve-interstitial-cells-by-inhibiting-%C3%AE-catenin-signaling
#19
Liu Fayuan, Chu Chong, Wei Qinyu, Shi Jiawei, Li Huadong, Dong Nianguo
Osteoblastic differentiation of aortic valve interstitial cells (AVICs) is the central process in the development of calcific aortic valve disease (CAVD). Metformin is a widely used first-line antidiabetic drug, and recently, pleiotropic benefits of metformin beyond hypoglycemia have been reported in the cardiovascular system. Here, we examined the effect of metformin on the osteoblastic differentiation of human AVICs. Our results showed that metformin ameliorated TGF-β1-induced production of osteogenic proteins Runx2 and osteopontin as well as calcium deposition in the cultured human AVICs...
April 18, 2018: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/29678618/concomitant-surgical-atrial-fibrillation-ablation-is-safe-and-efficacious-in-patients-undergoing-double-valve-replacement-a-cohort-study
#20
Guang Tong, Hao Yu, Xuan Zhou, Ben Zhang, Shenghui Bi, Lin Luo, Tao Yan, Xianyue Wang, Hua Lu, Tao Ma, Xiaowu Wang, Zhongchan Sun, Weida Zhang
BACKGROUND: Current European Society of Cardiology Guidelines recommend concomitant atrial fibrillation (AF) ablation for all symptomatic patients undergoing other cardiac surgeries, but the safety and potential benefits of concomitant atrial fibrillation (AF) ablation at the time of double valve replacement (DVR: aortic and mitral valve replacement) remains unexamined. MATERIALS AND METHODS: We conducted a retrospective review of 238 patients with AF who underwent DVR with or without concomitant surgical ablation (Ablation group, n=113; Non-ablation group, n=125) at a single institute from April 2006 to September 2011...
April 17, 2018: International Journal of Surgery
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