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https://www.readbyqxmd.com/read/29044996/lifestyle-habitat-and-farmers-risk-of-exposure-to-tick-bites-in-an-endemic-area-of-tick-borne-diseases-in-hungary
#1
S Li, L Juhász-Horváth, A Trájer, L Pintér, M D A Rounsevell, P A Harrison
Controlling tick bites on farmers is important to the management of tick-borne diseases and occupational health risks in agriculture. Based on an extensive household survey conducted between June and August 2015 with 219 farmers from western Hungary where tick-borne diseases are endemic, we analysed the pattern of farmers' self-reported contacts with ticks and investigated the potential interactions between farmers, landscape and the risk of exposure to tick bites. We developed a lifestyle typology based on farmers' socioeconomic profiles, farming objectives and time use patterns, and a habitat typology describing different configurations of tick habitats and agricultural areas in place of farming...
October 17, 2017: Zoonoses and Public Health
https://www.readbyqxmd.com/read/29042239/microbiota-of-field-collected-ixodes-scapularis-and-dermacentor-variabilis-from-eastern-and-southern-ontario-canada
#2
Katie M Clow, J Scott Weese, Joyce Rousseau, Claire M Jardine
The microbiota of hard ticks has been an area of growing interest due to the potential role that the broader microbial community may play in pathogen carriage and transmission. In the last two decades, Ontario, Canada has experienced rapid changes in the risk of tick-borne disease, primarily due to the range expansion of Ixodes scapularis. Another human-biter, Dermacentor variabilis, is a longstanding resident of the province, but currently poses minimal risk of pathogen transmission. To examine the microbiota of these two species, we collected adult and nymphal I...
September 20, 2017: Ticks and Tick-borne Diseases
https://www.readbyqxmd.com/read/29037090/prevention-and-the-state-of-knowledge-of-tick-borne-diseases-among-orienteers-in-poland
#3
Piotr Cych, Dorota Kiewra, Anna Szczepańska
No abstract text is available yet for this article.
October 16, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/29035855/transovarial-persistence-of-babesia-ovata-dna-in-a-hard-tick-haemaphysalis-longicornis-in-a-semi-artificial-mouse-skin-membrane-feeding-system
#4
Rika Umemiya-Shirafuji, Takeshi Hatta, Kazuhiro Okubo, Moeko Sato, Hiroki Maeda, Aiko Kume, Naoaki Yokoyama, Ikuo Igarashi, Naotoshi Tsuji, Kozo Fujisaki, Noboru Inoue, Hiroshi Suzuki
Bovine piroplasmosis, a tick-borne protozoan disease, is a major concern for the cattle industry worldwide due to its negative effects on livestock productivity. Toward the development of novel therapeutic and vaccine approaches, tick-parasite experimental models have been established to clarify the development of parasites in the ticks and the transmission of the parasites by ticks. A novel tick-Babesia experimental infection model recently revealed the time course of Babesia ovata migration in its vector Haemaphysalis longicornis, which is a dominant tick species in Japan...
December 20, 2017: Acta Parasitologica
https://www.readbyqxmd.com/read/29035848/animal-level-risk-factors-associated-with-babesia-and-theileria-infections-in-cattle-in-egypt
#5
Mohamed Abdo Rizk, Akram Salama, Shimaa Abd-El-Salam El-Sayed, Ahmed Elsify, Maged El-Ashkar, Hussam Ibrahim, Mohamed Youssef, Sabry El-Khodery
In present study, blood samples were collected randomly from 439 cows at three main regions of Egypt (northern, central and southern). Molecular diagnosis of Babesia and Theileria infections by PCR amplification of DNA (gene) fragments, then cloning and sequencing of the positive samples were conducted. A questionnaire was created to imply the assumed risk factors and logistic regression statistical analysis was carried out to appraise the potential factors on the animal level. The results revealed that 49 (11...
December 20, 2017: Acta Parasitologica
https://www.readbyqxmd.com/read/29032549/detection-of-bioluminescent-borrelia-burgdorferi-from-in-vitro-cultivation-and-during-murine-infection
#6
Jenny A Hyde, Jon T Skare
Borrelia burgdorferi, etiologic agent of Lyme disease, is the leading tick-borne disease in the United States with approximately 300,000 cases diagnosed annually. Disease occurs in stages beginning localized infection at the site of a tick bite and progresses to disseminated infection when antibiotic treatment is not administered in a timely manner. A multi-systemic infection develops following dissemination to numerous immunoprotective tissues, such as the heart, bladder, and joints, resulting in late Lyme disease...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29032540/artificial-infection-of-ticks-with-borrelia-burgdorferi-using-a-microinjection-method-and-their-detection-in-vivo-using-quantitative-pcr-targeting-flab-rna
#7
Alexis A Smith, Xiuli Yang, Erol Fikrig, Utpal Pal
Borrelia burgdorferi is maintained in nature by a tick-rodent infection cycle where it traverses and colonizes a variety of host and vector tissues. A tick-borne murine model has been developed to study Lyme disease in the laboratory, which has a substantial impact in advancing our knowledge of spirochete infectivity and pathogenesis. Here, we detail a microinjection-based method for rapid and efficient infection of ticks with B. burgdorferi. While laboratory generation of B. burgdorferi-infected nymphs via natural larval engorgement on infected hosts and subsequent molting could take several weeks to months, the microinjection-based infection procedure requires only a few hours to generate infected ticks and allows introduction of defined quantities of spirochetes, including mutant isolates that are attenuated for infection in mice and thus cannot be naturally acquired by ticks...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29032532/genotyping-strains-of-lyme-disease-agents-directly-from-ticks-blood-or-tissue
#8
Alan G Barbour, Vanessa J Cook
The tick-borne spirochetes that cause Lyme disease in North America and Eurasia display strong linkage disequilibrium between certain chromosomal and plasmid loci within each three major geographic areas of their distribution. For strain typing for epidemiologic and ecologic purposes, the commonly used genotypes based on a single locus are the spacer between the 16S-23S ribosomal RNA and the ospC gene of a plasmid. A simple genotyping scheme based on the two loci allows for discrimination between strains representing all the areas of distribution...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29029730/assessing-the-diversity-of-rodent-borne-viruses-exploring-of-high-throughput-sequencing-and-classical-amplification-sequencing-approaches
#9
Stephan Drewes, Petra Straková, Jan F Drexler, Jens Jacob, Rainer G Ulrich
Rodents are distributed throughout the world and interact with humans in many ways. They provide vital ecosystem services, some species are useful models in biomedical research and some are held as pet animals. However, many rodent species can have adverse effects such as damage to crops and stored produce, and they are of health concern because of the transmission of pathogens to humans and livestock. The first rodent viruses were discovered by isolation approaches and resulted in break-through knowledge in immunology, molecular and cell biology, and cancer research...
2017: Advances in Virus Research
https://www.readbyqxmd.com/read/29026617/cerebral-vasculitis-and-intracranial-multiple-aneurysms-in-a-child-with-lyme-neuroborreliosis
#10
Elisa Kortela, Jukka Hytönen, Jussi Numminen, Margit Overmyer, Harri Saxen, Jarmo Oksi
Introduction. Lyme borreliosis is a multisystem tick-borne disease caused by Borrelia burgdorferi. Neurological manifestations are reported in up to 15 % of adult patients with Lyme disease, while the frequency among children is higher. The most common manifestations are painful radiculopathy, facial nerve paresis and lymphocytic meningitis. Epileptic seizures and cerebral vasculitis with stroke or aneurysms are very rare complications. Case presentation. We describe a paediatric patient with sensorineural auditory dysfunction, headache, fatigue and epileptic seizures as sequelae of meningoencephalitis/Lyme neuroborreliosis (LNB) caused by B...
April 2017: JMM Case Reports
https://www.readbyqxmd.com/read/29024765/identification-of-2-deoxy-2-fluorocytidine-as-a-potent-inhibitor-of-crimean-congo-hemorrhagic-fever-virus-replication-using-a-recombinant-fluorescent-reporter-virus
#11
Stephen R Welch, Florine E M Scholte, Mike Flint, Payel Chatterjee, Stuart T Nichol, Éric Bergeron, Christina F Spiropoulou
Crimean-Congo hemorrhagic fever virus (CCHFV), a tick-borne orthonairovirus, causes a severe hemorrhagic disease in humans (Crimean-Congo hemorrhagic fever, CCHF). Currently, no vaccines are approved to prevent CCHF; treatment is limited to supportive care and the use of ribavirin, the therapeutic benefits of which remain unclear. CCHF is part of WHO's priority list of infectious diseases warranting further research and development. To aid in the identification of new antiviral compounds, we generated a recombinant CCHFV expressing a reporter protein, allowing us to quantify virus inhibition by measuring the reduction in fluorescence in infected cells treated with candidate compounds...
October 9, 2017: Antiviral Research
https://www.readbyqxmd.com/read/29021088/the-impact-of-strain-specific-immunity-on-lyme-disease-incidence-is-spatially-heterogeneous
#12
Camilo E Khatchikian, Robert B Nadelman, John Nowakowski, Ira Schwartz, Gary P Wormser, Dustin Brisson
Lyme disease, caused by the bacterium Borrelia burgdorferi, is the most common tick-borne infection in the US. Recent studies have demonstrated that the incidence of human Lyme disease would have been even greater were it not for the presence of strain-specific immunity, which protects previously infected patients against subsequent infections by the same B. burgdorferi strain. Here, spatial heterogeneity is incorporated into epidemiological models to accurately estimate the impact of strain-specific immunity on human Lyme disease incidence...
August 25, 2017: Diagnostic Microbiology and Infectious Disease
https://www.readbyqxmd.com/read/29017579/surveillance-of-ixodes-ricinus-ticks-acari-ixodidae-in-iceland
#13
Matthias Alfredsson, Erling Olafsson, Matthias Eydal, Ester Rut Unnsteinsdottir, Kayleigh Hansford, William Wint, Neil Alexander, Jolyon M Medlock
BACKGROUND: Ixodes ricinus is a three-host tick, a principal vector of Borrelia burgdorferi (s.l.) and one of the main vectors of tick-borne encephalitis (TBE) virus. Iceland is located in the North Atlantic Ocean with subpolar oceanic climate. During the past 3-4 decades, average temperature has increased, supporting more favourable conditions for ticks. Reports of I. ricinus have increased in recent years. If these ticks were able to establish in a changing climate, Iceland may face new threats posed by tick-borne diseases...
October 10, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28991904/epidemiological-consequences-of-immune-sensitisation-by-pre-exposure-to-vector-saliva
#14
Tsukushi Kamiya, Megan A Greischar, Nicole Mideo
Blood-feeding arthropods-like mosquitoes, sand flies, and ticks-transmit many diseases that impose serious public health and economic burdens. When a blood-feeding arthropod bites a mammal, it injects saliva containing immunogenic compounds that facilitate feeding. Evidence from Leishmania, Plasmodium and arboviral infections suggests that the immune responses elicited by pre-exposure to arthropod saliva can alter disease progression if the host later becomes infected. Such pre-sensitisation of host immunity has been reported to both exacerbate and limit infection symptoms, depending on the system in question, with potential implications for recovery...
October 9, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28988038/innate-immune-transcriptomic-evaluation-of-pbmc-isolated-from-sheep-after-infection-with-e-ruminantium-welgevonden-strain
#15
T Nefefe, J Liebenberg, M van Kleef, H C Steyn, A Pretorius
Heartwater is a tick-borne non-infectious fatal disease of wild and domestic ruminants caused by the bacterium Ehrlichia ruminantium, transmitted by Amblyomma ticks. Although there is evidence that interferon-gamma (IFN-γ) controls E. ruminantium growth and that cellular immune responses could be protective, an effective recombinant vaccine for this disease is lacking. An overall analysis of which immune pathways are up- or down-regulated in sheep peripheral blood mononuclear cells is expected to lead to a better understanding of the global immune response of sheep to E...
October 4, 2017: Molecular Immunology
https://www.readbyqxmd.com/read/28987040/-history-of-the-study-epidemiology-of-the-disease-and-characterization-of-borrelia-burgdorferi-infection
#16
EDITORIAL
Tadeusz Płusa
From the beginning of the twentieth century interest in tick-borne borreliosis continues to be an important diagnostic and therapeutic problem. In 1977, in Lyme and Old Lyme, Cunnecticut, in the United States, arthritis and skin lesions were described in 12 children, which were associated with tick bites. The name of the place was called a syndrome of Lyme disease. Dr Willy Burgdorfer observed microaerophilic Gram-negative bacteria (Spirochetes) with a diameter of 0.3-0.5 µm and a length of about 20-30 µm, which were isolated from the tick colon...
September 29, 2017: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/28981693/molecular-detection-and-identification-of-rickettsia-species-in-ticks-acari-ixodidae-collected-from-belize-central-america
#17
Suppaluck Polsomboon, David F Hoel, Jittawadee R Murphy, Yvonne-Marie Linton, Maysa Motoki, Richard G Robbins, Kim Bautista, Ireneo Bricen O, Nicole L Achee, John P Grieco, Wei-Mei Ching, Chien-Chung Chao
Little is known about tick-borne rickettsial pathogens in Belize, Central America. We tested ixodid ticks for the presence of Rickettsia species in three of the six northern and western Belizean districts. Ticks were collected from domestic animals and tick drags over vegetation in 23 different villages in November 2014, February 2015, and May 2015. A total of 2,506 collected ticks were identified to the following species: Dermacentor nitens Neumann (46.69%), Rhipicephalus sanguineus (Latreille) (19.55%), Rhipicephalus microplus (Canestrini) (19...
July 25, 2017: Journal of Medical Entomology
https://www.readbyqxmd.com/read/28981687/mutation-in-the-sodium-channel-gene-corresponds-with-phenotypic-resistance-of-rhipicephalus-sanguineus-sensu-lato-acari-ixodidae-to-pyrethroids
#18
G M Klafke, R J Miller, J Tidwell, R Barreto, F D Guerrero, P E Kaufman, A A Pérez de León
The brown dog tick, Rhipicephalus sanguineus sensu lato (Latreille), is a cosmopolitan ectoparasite and vector of pathogens that kill humans and animals. Pyrethroids represent a class of synthetic acaricides that have been used intensely to try to control the brown dog tick and mitigate the risk of tick-borne disease transmission. However, acaricide resistance is an emerging problem in the management of the brown dog tick. Understanding the mechanism of resistance to acaricides, including pyrethroids, is important to adapt brown dog tick control strategies...
July 13, 2017: Journal of Medical Entomology
https://www.readbyqxmd.com/read/28978457/in-vitro-efficacy-of-a-botanical-acaricide-and-its-active-ingredients-against-larvae-of-susceptible-and-acaricide-resistant-strains-of-rhipicephalus-boophilus-microplus-canestrini-acari-ixodidae
#19
Nirbhay K Singh, Robert J Miller, Guilherme M Klafke, John A Goolsby, Donald B Thomas, Adalberto A Perez de Leon
Ticks and tick-borne diseases are a major constraint for a sustainable cattle industry in the tropical and subtropical regions of the world. The development of resistance to most of the commonly used acaricides has led to an assessment of herbal products for acaricidal activity as an eco-friendly tick control alternative. A botanical product, Essentria(®) IC-3 insect concentrate containing rosemary oil (10%), geraniol (5%) and peppermint oil (2%), acts on target pests by blocking octopamine. Essentria(®) IC-3 and its active components were evaluated for larvicidal activity against several susceptible and acaricide-resistant strains of the cattle fever tick, Rhipicephalus (Boophilus) microplus Canestrini by Larval Packet test using 14-21 d old unfed larvae...
September 14, 2017: Ticks and Tick-borne Diseases
https://www.readbyqxmd.com/read/28978456/evidence-based-tick-acaricide-resistance-intervention-strategy-in-uganda-concept-and-feedback-of-farmers-and-stakeholders
#20
Patrick Vudriko, James Okwee-Acai, Joseph Byaruhanga, Dickson Stuart Tayebwa, Robert Omara, Jeanne Bukeka Muhindo, Charles Lagu, Rika Umemiya-Shirafuji, Xuenan Xuan, Hiroshi Suzuki
The emergence of multi-acaricide resistant ticks has led to unprecedented level of acaricide failure in central and western Uganda. In the absence of a national acaricide resistance management strategy, the country's dairy sector is threatened by upsurge of ticks and tick-borne diseases. In this study, we developed a short-to-medium-term intervention approach called Evidence-Based Acaricide Tick Control (EBATIC): Identify, Test, Intervene and Eradicate (IT-IE). Furthermore, the perception of 199 farmers and extension workers, 12 key informants in four districts and 47 stakeholders in the animal industry in Uganda were assessed using semi-structured questionnaires...
September 21, 2017: Ticks and Tick-borne Diseases
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