Antonio Procopio, Francesco Radico, Felice Gragnano, Chiara Ghiglieno, Gaetano Fassini, Annalisa Filtz, Alessandro Barbarossa, Daniele Sacchetta, Massimiliano Faustino, Fabrizio Ricci, Antonio Dello Russo, Paolo Calabrò, Giuseppe Patti, Sabina Gallina, Giulia Renda
BACKGROUND: Transcatheter left atrial appendage occlusion (LAAO) has emerged as an alternative treatment for stroke prevention in patients with atrial fibrillation (AF) at high risk of thromboembolism, who cannot tolerate long-term oral anticoagulation (OAC). Questions persist regarding effectiveness and safety of this treatment and the optimal post-interventional antithrombotic regimen after LAAO. METHODS: We retrospectively gathered data from 428 patients who underwent percutaneous LAAO in 6 Italian high-volume centres, aimed at describing the real-world utilization, safety, and effectiveness of LAAO procedures, also assessing the clinical outcomes associated with different antithrombotic strategies...
April 2024: IJC Heart & Vasculature