Daniel L Drane, Emma Acerbo, Anna Rogers, Nigel P Pedersen, Adam Williamson, Matthew A Stern, Adam S Dickey, Brian M Howard, Donald J Bearden, Noah Okada, Ekaterina Staikova, Claire Anne Gutekunst, Abdulrahman Alwaki, Timothy Gershon, Viktor Jirsa, Robert E Gross, David W Loring, Ammar Kheder, Jon T Willie
The conventional intracarotid amobarbital (Wada) test has been used to assess memory function in patients being considered for temporal lobe epilepsy (TLE) surgery. Minimally invasive approaches that target the medial temporal lobe (MTL) and spare neocortex are increasingly used, but a knowledge gap remains in how to assess memory and language risk from these procedures. We retrospectively compared results of two versions of the Wada test, the intracarotid artery (ICA-Wada) and posterior cerebral artery (PCA-Wada) approaches, with respect to predicting subsequent memory and language outcomes, particularly after stereotactic laser amygdalohippocampotomy (SLAH)...
March 26, 2024: medRxiv