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https://www.readbyqxmd.com/read/29718521/associate-degree-in-nursing-to-bachelor-of-science-in-nursing-graduates-education-and-their-perceived-ability-to-keep-patients-safe
#1
Allison Brandt Anbari, Amy Vogelsmeier
BACKGROUND: Associate Degree in Nursing (ADN)-to-Bachelor of Science in Nursing (BSN) programs are designed to advance the ADN-prepared RNs' clinical reasoning and analytical skills. However, little is known about exactly how their BSN education may improve their clinical practice, specifically in the area of patient safety. METHOD: During semi-structured one-to-one interviews, ADN-to-BSN graduates were asked about their educational process and the perceived affect their education made on their ability to keep patients safe...
May 1, 2018: Journal of Nursing Education
https://www.readbyqxmd.com/read/29694926/gh-prevents-adipogenic-differentiation-of-mesenchymal-stromal-stem-cells-derived-from-human-trabecular-bone-via-canonical-wnt-signaling
#2
Simona Bolamperti, Michela Signo, Alice Spinello, GianLuigi Moro, Gianfranco Fraschini, Francesca Guidobono, Alessandro Rubinacci, Isabella Villa
The imbalance between osteogenesis and adipogenesis, which naturally accompanies bone marrow senescence, may contribute to the development of bone-associated diseases, like osteoporosis. In the present study, using primary human mesenchymal stromal cells (hMSCs) isolated from trabecular bone, we assessed the possible effect of GH on hMSC differentiation potential into adipocytes. GH (5 ng/ml) significantly inhibited the lipid accumulation in hMSCs cultured for 14 days in lipogenic medium. GH decreased the expression of the adipogenic genes, CCAAT/enhancer-binding protein alpha (C/EBPα) and adiponectin (ADN) as well as the expression of two lipogenesis-related enzymes, lipoprotein lipase (LPL) and acethylCoA carboxylase (ACACA)...
April 22, 2018: Bone
https://www.readbyqxmd.com/read/29676866/detecci%C3%A3-n-y-expresi%C3%A3-n-de-superant%C3%A3-genos-y-de-resistencia-antimicrobiana-en-aislamientos-obtenidos-de-mujeres-portadoras-de-staphylococcus-aureus-que-cuidan-y-alimentan-ni%C3%A3-os
#3
Yina Marcela Guaca-González, Gladys Fernanda Flórez-Restrepo, José Ignacio Moncayo-Ortíz, Jorge Santacruz-Ibarra, Adalucy Álvarez-Aldana
Introducción. Staphylococcus aureus coloniza mucosas y piel, y causa graves infecciones en el hombre y los animales. Es importante establecer el estatus de portadoras de cepas enterotoxigénicas de este microorganismo en manipuladoras de alimentos, con el fin de prevenir intoxicaciones alimentarias.Objetivo. Establecer las correlaciones entre los genes de enterotoxinas clásicas, el gen tsst-1, la producción de toxinas en cultivo y la resistencia antimicrobiana en aislamientos de S. aureus provenientes de manipuladoras de alimentos que cuidan niños en sus comunidades...
March 15, 2018: Biomédica: Revista del Instituto Nacional de Salud
https://www.readbyqxmd.com/read/29605616/comparison-of-heterotrophic-and-autotrophic-denitrification-processes-for-nitrate-removal-from-phosphorus-limited-surface-water
#4
Zheng Wang, Shengbing He, Jungchen Huang, Weili Zhou, Wanning Chen
Phosphorus (P) limitation has been demonstrated for micro-polluted surface water denitrification treatment in previous study. In this paper, a lab-scale comparative study of autotrophic denitrification (ADN) and heterotrophic denitrification (HDN) in phosphorus-limited surface water was investigated, aiming to find out the optimal nitrogen/phosphorus (N/P) ratio and the mechanism of the effect of P limitation on ADN and HDN. Furthermore, the optimal denitrification process was applied to the West Lake denitrification project, aiming to improve the water quality of the West Lake from worse than grade V to grade IV (GB3838-2006)...
March 29, 2018: Environmental Pollution
https://www.readbyqxmd.com/read/29602116/increasing-atmospheric-deposition-nitrogen-and-ammonium-reduced-microbial-activity-and-changed-the-bacterial-community-composition-of-red-paddy-soil
#5
Fengwu Zhou, Jian Cui, Jing Zhou, John Yang, Yong Li, Qiangmei Leng, Yangqing Wang, Dongyi He, Liyan Song, Min Gao, Jun Zeng, Andy Chan
Atmospheric deposition nitrogen (ADN) increases the N content in soil and subsequently impacts microbial activity of soil. However, the effects of ADN on paddy soil microbial activity have not been well characterized. In this study, we studied how red paddy soil microbial activity responses to different contents of ADN through a 10-months ADN simulation on well managed pot experiments. Results showed that all tested contents of ADN fluxes (27, 55, and 82kgNha-1 when its ratio of NH4 + /NO3 - -N (RN ) was 2:1) enhanced the soil enzyme activity and microbial biomass carbon and nitrogen and 27kgNha-1 ADN had maximum effects while comparing with the fertilizer treatment...
March 27, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29570503/a-nursing-partnership-to-accelerate-academic-progression
#6
Sharon Kumm, Delois Laverentz
Associate degree nursing faculty in a Midwestern state reported that their students were being excluded from many clinical experiences and that their graduates were not being hired in Magnet® or Magnet-seeking hospitals. University and community college faculty formed a partnership to promote academic progression. Barriers of residency requirements, financial aid, and accreditation were overcome. Students complete all BSN prerequisites, take ADN and BSN courses simultaneously, graduate with both degrees, and take the national licensure examination...
March 22, 2018: Nursing Education Perspectives
https://www.readbyqxmd.com/read/29540173/adiponectin-and-adiponectin-receptor-1-overexpression-enhance-inflammatory-bowel-disease
#7
Yu-Ju Peng, Tang-Long Shen, Yu-Shan Chen, Harry John Mersmann, Bing-Hsien Liu, Shih-Torng Ding
BACKGROUND: Adiponectin (ADN) is an adipokine derived from adipocytes. It binds to adiponectin receptor 1 and 2 (AdipoR1 and R2) to exert its function in regulating whole-body energy homeostasis and inflammatory responses. However, the role of ADN-AdipoR1 signaling in intestinal inflammation is controversial, and its role in the regulation of neutrophils is still unclear. Our goal was to clarify the role of AdipoR1 signaling in colitis and the effects on neutrophils. METHODS: We generated porcine AdipoR1 transgenic mice (pAdipoR1 mice) and induced murine colitis using dextran sulfate sodium (DSS) to study the potential role of AdipoR1 in inflammatory bowel disease...
March 14, 2018: Journal of Biomedical Science
https://www.readbyqxmd.com/read/29526625/legacy-effect-in-combined-diabetic-renal-multifactorial-intervention-in-patients-with-advanced-diabetic-nephropathy
#8
Jose Kuzhively, Bettina Tahsin, Peter Hart, Leon Fogelfeld
AIM: Evaluate legacy effect on renal outcomes after the end of a multifactorial-multidisciplinary intervention in patients with advanced diabetic nephropathy (ADN trial) CKD 3-4. METHODS: A retrospective electronic review was conducted of 72 patients who completed the ADN trial ESRD-free with subsequent follow-up of two years or until ESRD development. RESULTS: At baseline, reflecting ADN trial end, 38 post-intervention and 34 post-control patients were similar except for lower HbA1c, SBP and age in the post-intervention group...
May 2018: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/29469829/measurement-of-multispecies-concentration-and-gas-temperature-in-an-ammonium-dinitramide-based-thruster-by-tunable-diode-lasers
#9
Hui Zeng, Fei Li, Xilong Yu, Dongbin Ou, Lianzhong Chen
In this paper, quantitative experiments were made to measure the concentration of key intermediate products (CO, N2 O, and NO) and the gas temperature for combustion flow based on near-infrared and mid-infrared laser absorption spectroscopy. This paper used the developed diagnostic system to study two main ignition modes of a real 1-Newton thruster based on ammonium dinitramide (ADN): steady-state firing and pulse-mode firing over a feed pressure of 5-12 bar. The steady-state firing experiments distinguished the whole process into catalytic decomposition stage and combustion stage, experimentally demonstrating the combustion kinetics mechanism of an ADN monopropellant...
February 20, 2018: Applied Optics
https://www.readbyqxmd.com/read/29398220/self-organized-attractor-dynamics-in-the-developing-head-direction-circuit
#10
Joshua P Bassett, Thomas J Wills, Francesca Cacucci
Head direction (HD) cells are neurons found in an extended cortical and subcortical network that signal the orientation of an animal's head relative to its environment [1-3]. They are a fundamental component of the wider circuit of spatially responsive hippocampal formation neurons that make up the neural cognitive map of space [4]. During post-natal development, HD cells are the first among spatially modulated neurons in the hippocampal circuit to exhibit mature firing properties [5, 6], but before eye opening, HD cell responses in rat pups have low directional information and are directionally unstable [7, 8]...
February 19, 2018: Current Biology: CB
https://www.readbyqxmd.com/read/29384571/interprofessional-education-on-adverse-childhood-experiences-for-associate-degree-nursing-students
#11
Jeanette M Olsen, Sarah L Warring
BACKGROUND: The health impact of adverse childhood experiences (ACEs) is significant. Nurses need knowledge and must work in multidisciplinary teams to address this problem. This study examined the effects of an interprofessional education (IPE) activity with nonhealth care students on associate degree nursing (ADN) students' ACEs knowledge and perspectives on IPE. METHOD: The mixed-methods approach used a quasi-experimental pretest-posttest design with an intervention and control group and thematic analysis of focus group data...
February 1, 2018: Journal of Nursing Education
https://www.readbyqxmd.com/read/29339376/tumor-immunity-and-survival-as-a-function-of-alternative-neopeptides-in-human-cancer
#12
Andrew J Rech, David Balli, Alejandro Mantero, Hemant Ishwaran, Katherine L Nathanson, Ben Z Stanger, Robert H Vonderheide
The immune system exerts antitumor activity via T cell-dependent recognition of tumor-specific antigens. Although the number of tumor neopeptides-peptides derived from somatic mutations-often correlates with immune activity and survival, most classically defined high-affinity neopeptides (CDNs) are not immunogenic, and only rare CDNs have been linked to tumor rejection. Thus, the rules of tumor antigen recognition remain incompletely understood. Here, we analyzed neopeptides, immune activity, and clinical outcome from 6,324 patients across 27 tumor types...
January 16, 2018: Cancer Immunology Research
https://www.readbyqxmd.com/read/29326116/behavioural-responses-to-infrasonic-particle-acceleration-in-cuttlefish
#13
Maria Wilson, Jens Ådne Rekkedal Haga, Hans Erik Karlsen
Attacks by aquatic predators generate frontal water disturbances characterised by low-frequency gradients in pressure and particle motion. Low-frequency hearing is highly developed in cephalopods. Thus, we examined behavioural responses in juvenile cuttlefish to infrasonic accelerations mimicking main aspects of the hydrodynamic signals created by predators. In the experimental set-up, animals and their surrounding water moved as a unit to minimise lateral line activation and to allow examination of the contribution by the inner ear...
January 11, 2018: Journal of Experimental Biology
https://www.readbyqxmd.com/read/29300298/supported-ni-catalyst-for-liquid-phase-hydrogenation-of-adiponitrile-to-6-aminocapronitrile-and-hexamethyenediamine
#14
Chengqiang Wang, Zekun Jia, Bin Zhen, Minghan Han
Supported Ni catalysts prepared under different conditions, for liquid phase hydrogenation of adiponitrile (ADN) to 6-aminocapronitrile (ACN) and hexamethyenediamine (HMD), were investigated. The highly reactive imine intermediate can form condensation byproducts with primary amine products (ACN and HMD), which decreased the yield coefficient of primary amines. The catalysts support, condition of catalyst preparation and dosage of additive were studied to improve the yield. A highly dispersed Ni/SiO₂ catalyst prepared by the direct reduction of Ni(NO₃)₂/SiO₂ suppressed the condensation reactions by promoting the hydrogenation of adsorbed imines, and it gave the improved hydrogenation activity of 0...
January 4, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29277251/-characterization-of-the-genetic-variability-of-field-strains-of-brucella-canis-isolated-in-antioquia
#15
Juana L Vidal Arboleda, Luisa F Ortiz Roman, Martha Olivera Angel
Brucella canis is a facultative intracellular pathogen responsible for canine brucellosis, a zoonotic disease that affects canines, causing abortions and reproductive failure; and the production of non-specific symptoms in humans. In 2005 the presence of B. canis in Antioquia was demonstrated and the strains were identified as type 2. The sequencing of the genome of a field strain denoted Brucella canis str. Oliveri, showed species-specific indel events, which led us to investigate the genomic characteristics of the B...
December 22, 2017: Revista Argentina de Microbiología
https://www.readbyqxmd.com/read/29274332/abnormal-cannabidiol-confers-cardioprotection-in-diabetic-rats-independent-of-glycemic-control
#16
Asmaa I Matouk, Ashraf Taye, Mohamed A El-Moselhy, Gehan H Heeba, Abdel A Abdel-Rahman
Chronic GPR18 activation by its agonist abnormal cannabidiol (trans-4-[3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl]-5-pentyl-1,3-benzenediol; abn-cbd) improves myocardial redox status and function in healthy rats. Here, we investigated the ability of abn-cbd to alleviate diabetes-evoked cardiovascular pathology and the contribution of GPR18 to this effect. Four weeks after diabetes induction by streptozotocin (STZ, 55mg/kg; i.p), male Wistar rats received abn-cbd, the GPR18 antagonist (1,3-dimethoxy-5-methyl-2-[(1R,6R)-3-methyl-6-(1-methylethenyl)-2-,cyclohexen-1-yl]benzene;O-1918), their combination (100µg/kg/day, i...
February 5, 2018: European Journal of Pharmacology
https://www.readbyqxmd.com/read/29243561/patient-safety-communication-among-differently-educated-nurses-converging-and-diverging-meaning-systems
#17
Allison Brandt Anbari, Amy Vogelsmeier, Debbie S Dougherty
Studies that suggest an increased number of bachelor's prepared nurses (BSNs) at the bedside improves patient safety do not stratify their samples into traditional bachelor's and associates (ADN) to BSN graduates. This qualitative study investigated potential differences in patient safety meaning among BSNs and ADN to BSN graduates. Guided by the theory of Language Convergence/Meaning Divergence, interview data from eight BSN and eight ADN to BSN graduates were analyzed. Findings indicate there are two meaning levels or systems, the local level and the systemic level...
December 1, 2017: Western Journal of Nursing Research
https://www.readbyqxmd.com/read/29215742/effects-of-small-interfering-rna-targeting-tlr4-on-expressions-of-adipocytokines-in-obstructive-sleep-apnea-hyponea-syndrome-with-hypertension-in-a-rat-model
#18
Jing-Guo Wu, Nan Xun, Li-Jin Zeng, Zhen-Yu Li, Yan-Bing Liang, Hao Tang, Zhong-Fu Ma
We explored the effects of RNA interference-mediated silencing of TLR4 gene on expressions of adipocytokines in obstructive sleep apnea hyponea syndrome (OSAS) with hypertension in a rat model. Systolic blood pressure of caudal artery and physiological changes were observed when establishing rat models of OSAS with hypertension. Mature rat adipocytes were induced from separated and cultured primary rat adipocytes. To transfect rat mature adipocytes, TLR4 siRNA group and negative control (NC) siRNA group were established...
December 7, 2017: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/29209593/analysis-of-the-salivary-gland-transcriptome-of-unfed-and-partially-fed-amblyomma-sculptum-ticks-and-descriptive-proteome-of-the-saliva
#19
Eliane Esteves, Sandra R Maruyama, Rebeca Kawahara, André Fujita, Larissa A Martins, Adne A Righi, Francisco B Costa, Giuseppe Palmisano, Marcelo B Labruna, Anderson Sá-Nunes, José M C Ribeiro, Andréa C Fogaça
Ticks are obligate blood feeding ectoparasites that transmit a wide variety of pathogenic microorganisms to their vertebrate hosts. Amblyomma sculptum is vector of Rickettsia rickettsii , the causative agent of Rocky Mountain spotted fever (RMSF), the most lethal rickettsiosis that affects humans. It is known that the transmission of pathogens by ticks is mainly associated with the physiology of the feeding process. Pathogens that are acquired with the blood meal must first colonize the tick gut and later the salivary glands (SG) in order to be transmitted during a subsequent blood feeding via saliva...
2017: Frontiers in Cellular and Infection Microbiology
https://www.readbyqxmd.com/read/29173592/west-nile-virus-in-horses-during-the-summer-and-autumn-seasons-of-2015-and-2016-portugal
#20
Sílvia C Barros, Fernanda Ramos, Teresa Fagulha, Margarida Duarte, Ana Margarida Henriques, Helga Waap, Tiago Luís, Teresa Costa, Rita Amador, Sofia Quintans, Miguel Fevereiro
West Nile fever (WNF) is an emergent disease in Europe, under surveillance in the European Union. Following a 5-year period of apparent silence (autumn 2010 to summer 2015), West Nile virus (WNV) reemerged in the South of Portugal, in July 2015. Here we present data from the onset, geographic location within mainland Portugal, and outcome of clinical cases of WNV infection in horses in 2015 and 2016. During the transmission seasons of 2015 and 2016, twenty-seven horses, most symptomatic (n=20) were found positive to IgM, pr-E immunoglobulins and VNT, leading to the subsequent report to Animal Disease Notification System of the European Commission (ADNS) by the Portuguese National Authority for Animal Health...
December 2017: Veterinary Microbiology
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