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https://www.readbyqxmd.com/read/28228000/c60-fullerene-as-promising-therapeutic-agent-for-the-prevention-and-correction-of-skeletal-muscle-functioning-at-ischemic-injury
#1
D M Nozdrenko, D O Zavodovskyi, T Yu Matvienko, S Yu Zay, K I Bogutska, Yu I Prylutskyy, U Ritter, P Scharff
The therapeutic effect of pristine C60 fullerene aqueous colloid solution (C60FAS) on the functioning of the rat soleus muscle at ischemic injury depending on the time of the general pathogenesis of muscular system and method of administration C60FAS in vivo was investigated. It was found that intravenous administration of C60FAS is the optimal for correction of speed macroparameters of contraction for ischemic muscle damage. At the same time, intramuscular administration of C60FAS shows pronounced protective effect in movements associated with the generation of maximum force responses or prolonged contractions, which increase the muscle fatigue level...
December 2017: Nanoscale Research Letters
https://www.readbyqxmd.com/read/28227843/investigating-motor-imagery-tasks-by-their-neural-effects-a-case-study
#2
I E Nicolae, M M C Stefan, B Hurezeanu, D D Taralunga, R Strungaru, T M Vasile, O A Bajenaru, G M Ungureanu, I E Nicolae, M M C Stefan, B Hurezeanu, D D Taralunga, R Strungaru, T M Vasile, O A Bajenaru, G M Ungureanu, B Hurezeanu, R Strungaru, G M Ungureanu, O A Bajenaru, D D Taralunga, T M Vasile, I E Nicolae, M M C Stefan
Motor imagery, one of the first investigated neural process for Brain-Computer Interfaces (BCIs) still provides a great challenge nowadays. Aiming a better and more accurate control, multiple researches have been conducted by the scientific community. Nevertheless, there is still no robust and confident application developed. In order to augment the potential referring to motor imagery, and to attract user's interest, we propose multiple motor imagery tasks in combination with different visual or auditory stimuli...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227026/the-effects-of-perceived-usb-delay-for-sensor-and-embedded-system-development
#3
J Du, D Kade, C Gerdtman, O Ozcan, M Linden, J Du, D Kade, C Gerdtman, O Ozcan, M Linden, O Ozcan, M Linden, D Kade, C Gerdtman, J Du
Perceiving delay in computer input devices is a problem which gets even more eminent when being used in healthcare applications and/or in small, embedded systems. Therefore, the amount of delay found as acceptable when using computer input devices was investigated in this paper. A device was developed to perform a benchmark test for the perception of delay. The delay can be set from 0 to 999 milliseconds (ms) between a receiving computer and an available USB-device. The USB-device can be a mouse, a keyboard or some other type of USB-connected input device...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226547/portable-electrocardiogram-device-using-android-smartphone
#4
S G E Brucal, G K D Clamor, L A O Pasiliao, J P F Soriano, L P M Varilla, S G E Brucal, G K D Clamor, L A O Pasiliao, J P F Soriano, L P M Varilla, J P F Soriano, L P M Varilla, S G E Brucal, L A O Pasiliao, G K D Clamor
Portable electrocardiogram (ECG) capturing device can be interfaced to a smart phone installed with an android-based application (app). This app processes and analyses the data sent by the device to provide an interpretation of the patient/user's heart current condition (e.g.: beats per minute, heart signal waveform, R-R interval). The ECG recorded by the app is stored in the smart phone's Secure Digital (SD) card and cloud storage which can be accessed remotely by a physician to aid in providing medical diagnosis...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226373/microvascular-flaps-in-nasal-reconstruction
#5
Irene A Kim, Kofi D O Boahene, Patrick J Byrne, Shaun C Desai
Nasal reconstruction for subtotal and total rhinectomy defects is a challenging endeavor, which requires technical finesse, a keen artistic eye, and the ability to anticipate long-term changes that accompany postoperative healing. While local and regional flaps have traditionally been utilized to reconstitute missing nasal elements, certain situations may not provide sufficient or acceptable tissue for optimal reconstruction. In these situations, the three major components of the nose-lining, structural support, and external skin-may require reconstruction with tissues harvested from distant sites through microvascular free tissue transfer...
February 2017: Facial Plastic Surgery: FPS
https://www.readbyqxmd.com/read/28226310/adhesion-of-ligand-conjugated-biosynthesized-magnetite-nanoparticles-to-triple-negative-breast-cancer-cells
#6
John D Obayemi, Jingjie Hu, Vanessa O Uzonwanne, Olushola S Odusanya, Karen Malatesta, Nicolas Anuku, Winston O Soboyejo
This paper presents the results of an experimental study of the adhesion forces between components of model conjugated magnetite nanoparticle systems for improved selectivity in the specific targeting of triple negative breast cancer. Adhesion forces between chemically synthesized magnetite nanoparticles (CMNPs), biosynthesized magnetite nanoparticles (BMNPs), as well as their conjugated systems and triple negative breast cancer cells (MDA-MB-231) or normal breast cells (MCF 10A) are elucidated at a nanoscale...
February 6, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28226294/extruded-dielectric-sample-tubes-of-complex-cross-section-for-epr-signal-enhancement-of-aqueous-samples
#7
Jason W Sidabras, Richard R Mett, James S Hyde
This paper builds on the work of Mett and Hyde (2003) and Sidabras et al. (2005) where multiple flat aqueous sample cells placed perpendicular to electric fields in microwave cavities were used to reduce the RF losses and increase the EPR signal. In this work, we present three novel sample holders for loop-gap resonators (LGRs) and cylindrical cavity geometries. Two sample holders have been commissioned and built by polytetrafluoroethylene (PTFE) extrusion techniques: a 1mm O.D. capillary with a septum down the middle, named DoubleDee, and a 3...
February 14, 2017: Journal of Magnetic Resonance
https://www.readbyqxmd.com/read/28226293/physico-chemical-characterization-and-antibacterial-activity-of-inclusion-complexes-of-hyptis-martiusii-benth-essential-oil-in-%C3%AE-cyclodextrin
#8
Tatianny A Andrade, Thiago S Freitas, Francielly O Araújo, Paula P Menezes, Grace Anne A Dória, Alessandra S Rabelo, Lucindo J Quintans-Júnior, Márcio R V Santos, Daniel P Bezerra, Mairim R Serafini, Irwin Rose A Menezes, Paula Santos Nunes, Adriano A S Araújo, Maria S Costa, Fábia F Campina, Antonia T L Santos, Ana R P Silva, Henrique D M Coutinho
Cyclodextrins (CDs) have been used as important pharmaceutical excipients for improve the physicochemical properties of the drugs of low solubility as the essential oil of Hyptis martiusii. This oil is important therapeutically, but the low solubility and bioavailability compromises your use. Therein, the aim of this study was to obtain and to characterize physico-chemically the samples obtained by physical mixture (PM), paste complexation (PC) and slurry complexation (SC) of the essential oil Hyptis martiusii (EOHM) in β-CD, and to compare the antibacterial and modulatory-antibiotic activity of products obtained and oil free...
February 19, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28226267/a-simple-lc-ms-ms-method-for-the-simultaneous-quantification-of-resveratrol-and-its-major-phase-ii-metabolites-assessment-of-their-urinary-and-biliary-excretions-in-rats
#9
Zhixia Qiu, Jiaojiao Yu, Yu Dai, Xijing Chen, Fang Huang, Ning Li
Trans-resveratrol (Res) is rapidly metabolized, extensively distributed into various tissues and mainly excreted by urine. The present study aimed to establish a simple LC-MS/MS method to simultaneously quantify Res and its major phase II metabolites (Res-3-O-β-d-glucuronide, R3G; Res-4'-O-β-d-glucuronide, R4'G; Res-resveratrol 3-sulfate, R3S; and Res-4'-sulfate, R4'S), and apply this method to assess their urinary and biliary excretions in rats. A simplified salting-out assisted liquid-liquid extraction (SALLE) strategy was developed to prepare samples with acetonitrile-methanol mixture (8:2, v/v) as extractant and ammonium acetate solution (10M) as salting-out reagent...
February 14, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/28225995/clinical-impact-of-thyroglobulin-tg-and-tg-autoantibody-tgab-measurements-in-needle-washouts-of-neck-lymph-node-biopsies-in-the-management-of-patients-with-papillary-thyroid-carcinoma
#10
M Cecilia Martins-Costa, Rui M B Maciel, Teresa S Kasamatsu, Claudia C D Nakabashi, Cleber P Camacho, Felipe Crispim, Elza S Ikejiri, M Conceição O Mamone, Danielle M Andreoni, Rosa Paula M Biscolla
Objectives: The presence of thyroglobulin (Tg) in needle washouts of fine needle aspiration biopsy (Tg-FNAB) in neck lymph nodes (LNs) suspected of metastasis has become a cornerstone in the follow-up of patients with papillary thyroid carcinoma (PTC). However, there are limited data regarding the measurement of anti-Tg antibodies in these washouts (TgAb-FNAB), and it is not clear whether these antibodies interfere with the assessment of Tg-FNAB or whether there are other factors that would more consistently justify the finding of low Tg-FNAB in metastatic LNs...
February 13, 2017: Archives of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28225973/do-you-know-this-syndrome-leopard-syndrome
#11
Flávio Heleno da Silva Queiroz Cançado, Luis Candido Pinto da Silva, Paulo Franco Taitson, Ana Carolina Dias Viana de Andrade, Matheus Melo Pithon, Dauro Douglas Oliveira
Hypertrophic cardiomyopathy is known as Leopard syndrome, which is a mnemonic rule for multiple lentigines (L), electrocardiographic conduction abnormalities (E), ocular hypertelorism (O), pulmonary stenosis (P), abnormalities of genitalia (A), retardation of growth (R), and deafness (D). We report the case of a 12-year-old patient with some of the abovementioned characteristics: hypertelorism, macroglossia, lentigines, hypospadias, cryptorchidism, subaortic stenosis, growth retardation, and hearing impairment...
January 2017: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/28225888/local-inhibition-of-nitrergic-activity-in-tenotomized-rats-accelerates-muscle-regeneration-by-increasing-fiber-area-and-decreasing-central-core-lesions
#12
A D Seabra, S A S Moraes, E J O Batista, T B Garcia, M C Souza, K R M Oliveira, A M Herculano
Muscular atrophy is a progressive degeneration characterized by muscular proteolysis, loss of mass and decrease in fiber area. Tendon rupture induces muscular atrophy due to an intrinsic functional connection. Local inhibition of nitric oxide synthase (NOS) by Nω-nitro-L-arginine methyl ester (L-NAME) accelerates tendon histological recovery and induces functional improvement. Here we evaluate the effects of such local nitrergic inhibition on the pattern of soleus muscle regeneration after tenotomy. Adult male Wistar rats (240 to 280 g) were divided into four experimental groups: control (n=4), tenotomized (n=6), vehicle (n=6), and L-NAME (n=6)...
February 20, 2017: Brazilian Journal of Medical and Biological Research, Revista Brasileira de Pesquisas Médicas e Biológicas
https://www.readbyqxmd.com/read/28225739/damage-control-laparotomy-utilization-rates-are-highly-variable-among-level-i-trauma-centers-pragmatic-randomized-optimal-platelet-and-plasma-ratios-findings
#13
Justin Jeremiah Joseph Watson, Jamison Nielsen, Kyle Hart, Priya Srikanth, John D Yonge, Christopher R Connelly, Phillip M Kemp Bohan, Hillary Sosnovske, Barbara C Tilley, Gerald van Belle, Bryan A Cotton, Terence S OʼKeeffe, Eileen M Bulger, Karen J Brasel, John B Holcomb, Martin A Schreiber
BACKGROUND: Damage control laparotomy (DCL) is intended to limit deleterious effects from trauma-induced coagulopathy. DCL has been associated with mortality reduction, but may increase complications including sepsis, abscess, respiratory failure, hernia, and gastrointestinal fistula. We hypothesized that (1) DCL incidence would vary between institutions; (2) mortality rates would vary with DCL rates; (3) standard DCL criteria of pH, international normalized ratio, temperature and major intra-abdominal vascular injury would not adequately capture all patients...
March 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28225652/dna-vaccination-partially-protects-muskellunge-against-viral-hemorrhagic-septicemia-virus-vhsv-ivb
#14
Elena V Millard, Ashley M Bourke, Scott E LaPatra, Travis O Brenden, Scott D Fitzgerald, Mohamed Faisal
A DNA vaccine containing the glycoprotein (G) gene of the North American viral hemorrhagic septicemia virus (VHSV) genotype IVb was developed to evaluate the immune response of fish following vaccination and evaluate its efficacy in protecting a susceptible species, the Muskellunge Esox masquinongy, against VHSV-IVb challenge. Seven weeks (539 degree-days) following vaccination with 10 μg of either pVHSivb-G or a control plasmid, Muskellunge were challenged by immersion with 10(5) plaque-forming units (pfu)/mL of VHSV-IVb...
March 2017: Journal of Aquatic Animal Health
https://www.readbyqxmd.com/read/28225623/a-palladium-catalyzed-ullmann-cross-coupling-reductive-cyclisation-route-to-the-carbazole-natural-products-3-methyl-9h-carbazole-glycoborine-glycozoline-clauszoline-k-mukonine-and-karapinchamine-a
#15
Qiao Yan, Emma Gin, Malgorzata Wasinska-Kalwa, Martin Gerhardt Banwell, Paul D Carr
The title natural products 2-7 have been prepared by reductive cyclisation of the relevant 2-arylcyclohex-2-en-1-one (e.g. 20) to the corresponding tetrahydrocarbazole (e.g. 21) and dehydrogenation of this to give the target carbazole (e.g. 4). Compounds such as 20 were prepared using a palladium-catalyzed Ullmann cross-coupling reaction between the appropriate 2-iodocyclohex-2-en-1-one and o-halonitrobenzene.
February 22, 2017: Journal of Organic Chemistry
https://www.readbyqxmd.com/read/28225331/standing-on-the-shoulders-of-giants
#16
Peter D O Davies
No abstract text is available yet for this article.
March 1, 2017: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/28225184/bis-picolinamide-ruthenium-iii-dihalide-complexes-dichloride-to-diiodide-exchange-generates-single-trans-isomers-with-high-potency-and-cancer-cell-selectivity
#17
Aida M Basri, Rianne M Lord, Simon J Allison, Andrea Rodríguez-Bárzano, Stephanie J Lucas, Felix D Janeway, Helena J Shepherd, Christopher M Pask, Roger M Phillips, Patrick Columba McGowan
A library of new bis-picolinamide ruthenium(III) dihalide complexes of the type RuX2L2 (X = Cl or I and L = picolinamide) have been synthesized and characterized. They exhibit different picolinamide ligand binding modes, whereby one ligand is bound (N,N) and the other bound (N,O). Structural studies reveal a mixture of cis and trans isomers for the RuCl2L2 complexes but upon a halide exchange reaction to RuI2L2, only single trans isomers are present. High cytotoxic activity against human cancer cell lines was observed, with potencies for some complexes similar to or better than cisplatin...
February 22, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28225055/alcoholic-beverage-preference-and-diabetes-incidence-across-europe-the-consortium-on-health-and-ageing-network-of-cohorts-in-europe-and-the-united-states-chances-project
#18
D Sluik, N Jankovic, M Hughes, M G O'Doherty, B Schöttker, W Drygas, O Rolandsson, S Männistö, J M Ordóñez-Mena, J Ferrieres, C Bamia, G de Gaetano, J C Kiefte-De Jong, O H Franco, I Sluijs, A M W Spijkerman, S Sans, S Eriksson, D Kromhout, A Trichopoulou, T Wilsgaard, H Brenner, K Kuulasmaa, T Laatikainen, S Söderberg, L Iacoviello, P Boffetta, F Kee, E J M Feskens
BACKGROUND/OBJECTIVES: It is unknown if wine, beer and spirit intake lead to a similar association with diabetes. We studied the association between alcoholic beverage preference and type 2 diabetes incidence in persons who reported to consume alcohol. SUBJECTS/METHODS: Ten European cohort studies from the Consortium on Health and Ageing: Network of Cohorts in Europe and the United States were included, comprising participant data of 62 458 adults who reported alcohol consumption at baseline...
February 22, 2017: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28224720/pyridostigmine-bromide-versus-fludrocortisone-in-the-treatment-of-orthostatic-hypotension-in-parkinson-s-disease-a-randomized-controlled-trial
#19
S R Schreglmann, F Büchele, M Sommerauer, L Epprecht, G Kägi, S Hägele-Link, O Götze, L Zimmerli, D Waldvogel, C R Baumann
BACKGROUND AND PURPOSE: Evidence for effective treatment options for orthostatic hypotension (OH) in Parkinson's disease (PD) is scarce. Elevation of cholinergic tone with pyridostigmine bromide has been reported as a way to improve blood pressure (bp) regulation in neurogenic hypotension without causing supine hypertension. METHODS: This was a double-centre, double-blind, randomized, active-control, crossover, phase II non-inferiority trial of pyridostigmine bromide for OH in PD (clinicaltrials...
February 22, 2017: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/28224715/foot-and-mouth-disease-virus-serotype-sat1-in-cattle-nigeria
#20
D O Ehizibolo, A Haegeman, A R De Vleeschauwer, J U Umoh, H M Kazeem, E C Okolocha, S Van Borm, K De Clercq
The knowledge of foot-and-mouth disease virus (FMDV) dynamics and epidemiology in Nigeria and the West Africa subregion is important to support local and regional control plans and international risk assessment. Foot-and-mouth disease virus serotype South African territories (SAT)1 was isolated, identified and characterized from an FMD outbreak in cattle in Nigeria in 2015, 35 years after the last report of FMDV SAT1 in West Africa. The VP1 coding sequence of the Nigerian 2015 SAT1 isolates diverges from reported SAT1 topotypes resulting in a separate topotype...
February 21, 2017: Transboundary and Emerging Diseases
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