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https://www.readbyqxmd.com/read/28224374/mri-findings-of-knee-abnormalities-in-adolescent-and-adult-volleyball-players
#1
Heide Boeth, Aoife MacMahon, Felix Eckstein, Gerd Diederichs, Arne Schlausch, Wolfgang Wirth, Georg N Duda
BACKGROUND: To longitudinally and cross-sectionally evaluate knee abnormalities by sex and age in adolescent and adult volleyball athletes over 2 years using magnetic resonance imaging (MRI). METHODS: Thirty-six high-level volleyball athletes (18 adolescents: 56% female, mean age 16.0 ± 0.8 years; and 18 adults: 50% female, mean age 46.8 ± 5.1 years) were imaged by MRI at BL and at 2-year follow-up (FU). Prevalence and severity of cartilage lesions, subarticular bone marrow lesions (BMLs), subarticular cysts, osteophytes, and ligament and meniscus integrity were evaluated by sex and by age cohort (adolescents and adults) using the whole-organ MRI score (WORMS)...
December 2017: Journal of Experimental Orthopaedics
https://www.readbyqxmd.com/read/28213953/the-effects-of-acl-graft-placement-on-in-vivo-knee-function-and-cartilage-thickness-distributions
#2
REVIEW
Louis E DeFrate
Injuries to the anterior cruciate ligament (ACL) frequently lead to early-onset osteoarthritis. Despite advancement in surgical techniques, ACL reconstruction has a limited ability to prevent these degenerative changes. While previous studies have investigated knee function after ACL reconstruction, in vivo investigations of the effects of graft placement on in vivo joint function and cartilage health are limited. This review presents a series of studies that used novel imaging and 3D modeling techniques to determine the in vivo placement of the ACL graft on the femur using two different ACL reconstruction techniques...
February 18, 2017: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/28211591/magnetic-resonance-imaging-of-the-knee-an-overview-and-update-of-conventional-and-state-of-the-art-imaging
#3
Nicholas C Nacey, Matthew G Geeslin, Grady Wilson Miller, Jennifer L Pierce
: Magnetic resonance imaging (MRI) has become the preferred modality for imaging the knee to show pathology and guide patient management and treatment. The knee is one of the most frequently injured joints, and knee pain is a pervasive difficulty that can affect all age groups. Due to the diverse pathology, complex anatomy, and a myriad of injury mechanisms of the knee, the MRI knee protocol and sequences should ensure detection of both soft tissue and osseous structures in detail and with accuracy...
February 17, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28203112/bone-contusion-progression-from-traumatic-knee-injury-association-of-rate-of-contusion-resolution-with-injury-severity
#4
Douglas R Pedersen, Georges Y El-Khoury, Dan R Thedens, Mothana Saad-Eldine, Phinit Phisitkul, Annunziato Amendola
BACKGROUND: Bone contusions are frequently encountered in magnetic resonance imaging (MRI) evaluation of knee anterior cruciate ligament (ACL) injuries. Their role as indicators of injury severity remains unclear, primarily due to indeterminate levels of joint injury forces and to a lack of preinjury imaging. PURPOSE: The purpose of this study was to 1) quantify bone contusion pathogenesis following traumatic joint injuries using fixed imaging follow-ups, and 2) assess the feasibility of using longitudinal bone contusion volumes as an indicator of knee injury severity...
2017: Open Access Journal of Sports Medicine
https://www.readbyqxmd.com/read/28194878/platelet-activated-serum-might-have-a-therapeutic-effect-on-damaged-articular-cartilage
#5
Munetaka Yokoyama, Masato Sato, Yoshiki Tani, Miyuki Yokoyama, Mami Kokubo, Masayuki Yamato, Teruo Okano, Joji Mochida
Platelet-activated serum (PAS) was collected from rabbits. This contains high concentrations of growth factors, including vascular endothelial growth factor (VEGF), platelet-derived growth factor (PDGF)-BB, and transforming growth factor-beta (TGF-β). PAS was injected into the knee joints of Japanese White rabbits subjected to anterior cruciate ligament transection (ACL-T) to investigate its therapeutic effects on articular cartilage. The effect of Avastin (an anti-VEGF monoclonal antibody) on VEGF expression was also investigated...
February 14, 2017: Journal of Tissue Engineering and Regenerative Medicine
https://www.readbyqxmd.com/read/28193143/conscious-performance-and-arthroscopic-findings-in-athletes-with-anterior-cruciate-ligament-injuries-treated-via-conservative-therapy-during-the-competitive-season
#6
Yasushi Takata, Junsuke Nakase, Tatsuhiro Toratani, Hitoaki Numata, Takeshi Oshima, Katsuhiko Kitaoka, Hiroyuki Tsuchiya
PURPOSE: Athletes often receive conservative treatment for injured anterior cruciate ligaments (ACLs) so that they can continue to play to the end of their season. The purpose of this study was to examine the conscious performance and arthroscopic findings of athletes who received conservative therapy for ACL injuries. METHODS: Forty-two patients with ACL injuries underwent conservative treatment. After the season ended, ACL reconstruction was performed. We examined the following parameters: (1) time required for return to competition after injury, (2) conscious performance after return to competition, (3) whether the injured knee gave way during conservative therapy or after return to competition, and (4) cause of performance deterioration if applicable...
January 2017: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/28167976/chondroprotective-effects-and-multitarget-mechanisms-of-fu-yuan-capsule-in-a-rat-osteoarthritis-model
#7
Li Zeng, Cai Zhi Xiao, Zi Ting Deng, Rong Heng Li
Fu Yuan Capsule (FYC) has been clinically used for osteoarthritis (OA) and its related diseases for many years in China. However, its pharmacological mechanism remains unclear. This study aimed to investigate the potential chondroprotective effects of FYC on articular cartilage. Rat OA model was induced by anterior cruciate ligament transection. A group of rats was treated with FYC for 12 weeks. Joint structure, types I and II collagen, and proteoglycan were evaluated by histological examination. The expression of C-terminal crosslinking telopeptide of type II collagen, hydroxyproline, a disintegrin and metalloproteinase with thrombospondin motifs, matrix metalloproteinase, interleukin-1 beta, nitric oxide, prostaglandin E2, heat-shock protein 70, transforming growth factor-beta, osteoprotegerin, and receptor activator of nuclear factor κB ligand were detected...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28164045/ipsilateral-medial-and-lateral-discoid-meniscus-with-medial-meniscus-tear
#8
Kengo Shimozaki, Junsuke Nakase, Yoshinori Ohashi, Hitoaki Numata, Takeshi Oshima, Yasushi Takata, Hiroyuki Tsuchiya
INTRODUCTION: Discoid meniscus is a well-documented knee pathology, and there are many cases of medial or lateral discoid meniscus reported in the literature. However, ipsilateral concurrent medial and lateral discoid meniscus is very rare, and only a few cases have been reported. Herein, we report a case of concurrent medial and lateral discoid meniscus. CASE REPORT: A 27-year-old Japanese man complained of pain on medial joint space in his right knee that was diagnosed as a complete medial and lateral discoid meniscus...
September 2016: Journal of Orthopaedic Case Reports
https://www.readbyqxmd.com/read/28161746/correlation-between-osteoarthritic-changes-in-the-stifle-joint-in-dogs-and-the-results-of-orthopedic-radiographic-ultrasonographic-and-arthroscopic-examinations
#9
Gabriel Ignacio Ramírez-Flores, Javier Del Angel-Caraza, Israel Alejandro Quijano-Hernández, Don A Hulse, Brian S Beale, José Mauro Victoria-Mora
Osteoarthritis (OA) is a chronic, degenerative disease affecting the articular cartilage and subchondral bone that causes pain and inhibits movement. The stifle's joint fibrous capsule contains the synovial membrane, which produces cartilage nutrients. A ruptured cranial cruciate ligament injures the joint and produces OA. Osteoarthritis diagnosis starts with clinical radiographic and ultrasonographic tests, although the latter is not used very much in dog and cat clinics for this purpose. The objective of this study was to establish the correlation among the results of orthopedic, radiographic, ultrasonographic examinations and structural anatomical changes revealed by arthroscopic evaluation to diagnose stifle joint OA and determine risk factors in the dogs affected...
February 4, 2017: Veterinary Research Communications
https://www.readbyqxmd.com/read/28153474/feasibility-of-using-mris-to-create-subject-specific-parallel-mechanism-joint-models
#10
Simao Brito da Luz, Luca Modenese, Nicola Sancisi, Peter M Mills, Ben Kennedy, Belinda R Beck, David G Lloyd
Musculoskeletal models typically use generic 2D models for the tibiofemoral (TFJ) and patellofemoral (PFJ) joints, with a hinge talocrural joint (TCJ), which are scaled to each subject׳s bone dimensions. Alternatively joints' measured kinematics in cadavers are well-predicted using 3D cadaver-specific models. These employ mechanisms constrained by the articulations of geometric objects fitted to the joint׳s surfaces. In this study, we developed TFJ, PFJ and TCJ mechanism-based models off MRIs for fourteen participants and compared the estimated kinematics with those from published studies modified to be consistent with mechanisms models and subject-specific anatomical landmarks...
December 29, 2016: Journal of Biomechanics
https://www.readbyqxmd.com/read/28150869/biochemical-markers-of-cartilage-metabolism-are-associated-with-walking-biomechanics-six-months-following-anterior-cruciate-ligament-reconstruction
#11
Brian Pietrosimone, Richard F Loeser, J Troy Blackburn, Darin A Padua, Matthew S Harkey, Laura E Stanley, Brittney A Luc-Harkey, Veronica Ulici, Stephen W Marshall, Joanne M Jordan, Jeffery T Spang
The purpose of our study was to determine the association between biomechanical outcomes of walking gait (peak vertical ground reaction force [vGRF], vGRF loading rate [vGRF-LR] and knee adduction moment [KAM]) six months following anterior cruciate ligament reconstruction (ACLR) and biochemical markers of serum type-II collagen turnover (collagen type-II cleavage product to collagen type-II C-propeptide [C2C:CPII]), plasma degenerative enzymes (matrix metalloproteinase-3 [MMP-3]), and a pro-inflammatory cytokine (interleukin-6 [IL-6])...
February 2, 2017: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/28146402/a-multicenter-study-of-early-anti-inflammatory-treatment-in-patients-with-acute-anterior-cruciate-ligament-tear
#12
Christian Lattermann, Cale A Jacobs, Mary Proffitt Bunnell, Laura J Huston, Lee G Gammon, Darren L Johnson, Emily K Reinke, Janet L Huebner, Virginia B Kraus, Kurt P Spindler
BACKGROUND: It is increasingly recognized that biochemical abnormalities of the joint precede radiographic abnormalities of posttraumatic osteoarthritis (PTOA) by as much as decades. A growing body of evidence strongly suggests that the progression from anterior cruciate ligament (ACL) injury to PTOA is multifactorial, involving the interplay between biomechanical disturbances and biochemical homeostasis of articular cartilage. PURPOSE: The purposes of this randomized study using an acute ACL injury model were to (1) evaluate the natural progression of inflammatory and chondrodegenerative biomarkers, (2) evaluate the relationship between subjective reports of pain and inflammatory and chondrodegenerative biomarkers, and (3) determine if postinjury arthrocentesis and corticosteroid injection offer the ability to alter this biochemical cascade...
February 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28144717/-individualized-unicondylar-knee-replacement-use-of-patient-specific-implants-and-instruments
#13
J Arnholdt, B M Holzapfel, L Sefrin, M Rudert, J Beckmann, A F Steinert
OBJECTIVE: Unicompartmental knee replacement in patients with osteoarthritis (OA) of the medial compartment. Individualized instruments and implants with a planning protocol for optimal fit. The individualized instruments and implants (ConforMIS Inc.; Burlington, MA, USA) are manufactured based on a computed tomography scan of the affected lower extremity and are provided together with a planning protocol (iView®) of the surgery. INDICATIONS: Unicompartmental OA of the knee (Kellgren & Lawrence stage IV) or Morbus Ahlbäck after unsuccessful conservative or joint preserving surgery...
February 2017: Operative Orthopädie und Traumatologie
https://www.readbyqxmd.com/read/28144716/bicompartmental-individualized-knee-replacement-use-of-patient-specific-implants-and-instruments-iduo%C3%A2
#14
A F Steinert, J Beckmann, B M Holzapfel, M Rudert, J Arnholdt
OBJECTIVE: Bicompartmental knee replacement in patients with combined osteoarthritis (OA) of the medial or lateral and patellofemoral compartment. Patient-specific instruments and implants (ConforMIS iDuo™) with a planning protocol for optimal implant fit. INDICATIONS: Bicompartmental OA of the knee (Kellgren & Lawrence stage IV) affecting both the medial or lateral and patellofemoral compartment after unsuccessful conservative or joint-preserving surgery. CONTRAINDICATIONS: Tricompartmental OA, knee ligament instabilities, knee deformities >15° (varus, valgus, extension deficit)...
February 2017: Operative Orthopädie und Traumatologie
https://www.readbyqxmd.com/read/28144608/the-current-perspectives-of-stem-cell-therapy-in-orthopedic-surgery
#15
REVIEW
Serkan Akpancar, Oner Tatar, Hasan Turgut, Faruk Akyildiz, Safak Ekinci
CONTEXT: Musculoskeletal injuries may be painful, troublesome, life limiting and also one of the global health problems. There has been considerable amount of interest during the past two decades to stem cells and tissue engineering techniques in orthopedic surgery, especially to manage special and compulsive injuries within the musculoskeletal system. EVIDENCE ACQUISITION: The aim of this study was to present a literature review regarding the most recent progress in stem cell procedures and current indications in orthopedics clinical care practice...
December 2016: Archives of Trauma Research
https://www.readbyqxmd.com/read/28138717/-patellofemoral-arthroplasty
#16
M Cotic, P Forkel, A B Imhoff
OBJECTIVE: Isolated resurfacing of the trochlea using an inlay prosthesis without changing the complex kinematics of the patellofemoral joint. INDICATIONS: Symptomatic, isolated patellofemoral osteoarthritis or isolated osteochondral lesions, failed conservative and cartilage regeneration procedures. No or concurrently corrected ligament instability, tibiofemoral and patellofemoral malalignment. CONTRAINDICATIONS: Symptomatic patellofemoral osteoarthritis, inflammatory joint disease, chondrocalcinosis, chronic pain syndromes, active infections or knee ankylosis...
February 2017: Operative Orthopädie und Traumatologie
https://www.readbyqxmd.com/read/28131634/comminuted-intraarticular-fractures-of-the-tibial-plateau-lead-to-posttraumatic-osteoarthritis-of-the-knee-current-treatment-review
#17
REVIEW
Matthias Aurich, Veit Koenig, Gunther Hofmann
Posttraumatic osteoarthritis (PTOA) of the knee is a common complication after intra- and extra-articular fractures. Moreover, PTOA may also be a result of isolated cartilage defects, meniscus resections, and ligament injuries. There are various methods of treatment of knee joint fractures. However, in the final stage of a PTOA, when nonoperative treatment fails, endoprosthetic joint replacement is the method of choice. Primary total knee replacement (TKR) for the treatment for a fracture of the knee joint is a rare indication, even at major treatment centers...
January 25, 2017: Asian Journal of Surgery
https://www.readbyqxmd.com/read/28119800/ulna-rotation-osteotomy-in-complete-dislocation-of-the-distal-radioulnar-joint
#18
Markus Gabl, Rohit Arora, Eva Maria Gassner, Gernot Schmidle
Background Complete dislocation of the distal radioulnar joint (DRUJ) is a rare injury. Dislocation can present as uni- or multidirectional, acute or chronic, reducible or irreducible. It can occur due to isolated loss of ligamentous restraints or more frequent in Galeazzi - or Essex-Lopresti-type fractures. Case Description A 28-year-old man sustained a distal radius fracture and presented after conservative treatment with blocked supination. Examination revealed a malunion of the distal radius in combination with an irreducible dorsal dislocation of the DRUJ...
February 2017: Journal of Wrist Surgery
https://www.readbyqxmd.com/read/28116257/an-unusual-case-of-partial-anterior-cruciate-ligament-acl-tear-secondary-to-a-glass-foreign-body-in-an-adolescent-knee-joint
#19
Shishir S M, Abhay Harsh K, Kanagasabai R, James J Gnanadoss
INTRODUCTION: Various types of foreign bodies have been removed from the knee joint. We report an unusual case of partial anterior cruciate ligament (ACL) tear secondary to a glass foreign body in an adolescent knee joint. CASE REPORT: A 13-year-old boy presented with pain, swelling and deformity of the left knee since 4 days. X-Ray revealed a foreign body in the left knee joint. The glass foreign body remained in the subcutaneous tissue for few days and later migrated into the knee joint...
July 2016: Journal of Orthopaedic Case Reports
https://www.readbyqxmd.com/read/28112382/ginsenoside%C3%A2-rg5-treatment-inhibits-apoptosis-of-chondrocytes-and-degradation-of-cartilage-matrix-in-a-rat-model-of-osteoarthritis
#20
Ping Zhang
This study investigated the effect of ginsenoside‑Rg5 on the degradation of articular cartilage in osteoarthritis rat model and on induction of chondrocyte apoptosis. Osteoarthritis rat model was prepared by ligament transection and medial meniscus resection. The rats were then treated with different doses (1, 2, 5, 10 and 15 µM) of ginsenoside‑Rg5 for 48 h. The results from histopathological analysis revealed a significant (P=0.005) prevention of cartilage degradation in OA rat model by ginsenoside‑Rg5 treatment at 15 µM...
January 19, 2017: Oncology Reports
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