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Joint cartilage ligaments

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https://www.readbyqxmd.com/read/29138892/-partial-and-complete-joint-transplantation-with-fresh-osteochondral-allografts-the-flocsat-concept
#1
REVIEW
C Krettek, J-D Clausen, N Bruns, C Neunaber
Cartilage defects in adult patients do not heal well. Fresh osteochondral allograft (OCA) transplantation is based on mature, living, mechanically sound hyaline cartilage attached to a bone interface, which is brought into an osteochondral defect, where it becomes osseointegrated. According to current knowledge, intact hyaline cartilage tissue is immune privileged and does not, in contrast to bone, meniscus or ligaments, cause an immune reaction. The technique has the unique advantage of transplanting viable, mature and mechanically stable hyaline cartilage into the affected area...
November 2017: Der Unfallchirurg
https://www.readbyqxmd.com/read/29117248/medial-knee-loading-is-altered-in-subjects-with-early-osteoarthritis-during-gait-but-not-during-step-up-and-over-task
#2
Susana Meireles, Mariska Wesseling, Colin R Smith, Darryl G Thelen, Sabine Verschueren, Ilse Jonkers
This study evaluates knee joint loading during gait and step-up-and-over tasks in control subjects, subjects with early knee OA and those with established knee OA. Thirty-seven subjects with varying degrees of medial compartment knee OA severity (eighteen with early OA and sixteen with established OA), and nineteen healthy controls performed gait and step-up-and-over tasks. Knee joint moments, contact forces (KCF), the magnitude of contact pressures and center of pressure (CoP) location were analyzed for the three groups for both activities using a multi-body knee model with articular cartilage contact, 14 ligaments, and six degrees of freedom tibiofemoral and patellofemoral joints...
2017: PloS One
https://www.readbyqxmd.com/read/29103840/the-influence-of-full-thickness-chondral-defects-on-outcomes-following-meniscal-allograft-transplantation-a-comparative-study
#3
Bryan M Saltzman, Maximilian A Meyer, Timothy S Leroux, Matthew E Gilelis, Margot Debot, Adam B Yanke, Brian J Cole
PURPOSE: To compare a series of patients who underwent meniscus allograft transplantation (MAT) with full-thickness chondral defects (FTD) with those with no chondral defect (ND) with regard to the following: change in patient-reported outcomes (PROs) from baseline to 2-year follow-up and baseline to the final follow-up (including comparisons to minimal clinically important differences), complications and complication rates, reoperations and reoperation rates/timing, and failures and time to failure (revision MAT or conversion to total knee arthroplasty)...
November 2, 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/29099611/spect-ct-arthrography
#4
Ujwal Bhure, Justus E Roos, Maria Del Sol Pérez Lago, Isabelle Steurer, Hannes Grünig, Urs Hug, Klaus Strobel
Single photon emission CT (SPECT)/CT arthrography, the combination of CT arthrography and late phase bone SPECT/CT, has been developed in 2011 and so far used in knee, ankle and wrist joints. SPECT/CT offers functional information about increased bone turnover in combination with morphological details. Compared with SPECT/CT alone, additional intra-articular contrast enables the assessment of cartilage, menisci, ligaments and loose bodies. SPECT/CT arthrography is a promising alternative technique for the evaluation of internal derangement of joints in patients with MR contraindications and/or metallic implants...
November 16, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/29095402/mri-and-arthroscopy-correlation-in-the-patellofemoral-joint
#5
Lisa G M Friedman, Melissa S White, Patrick F Carroll, Jeffrey A Macalena, Elizabeth A Arendt, Jutta M Ellermann, Marc Tompkins
The patellofemoral joint is an articulation between the patella and the femoral trochlea, which serves to increase the lever arm of the extensor mechanism. The stability of the patella within the trochlear groove is supported statically by the bony confines of the groove itself, as well as the medial patellofemoral ligament, and dynamically by the vastus musculature. Pathologic changes seen on magnetic resonance imaging (MRI) are frequently well correlated with findings found by arthroscopy at the time of surgery...
December 2017: Sports Medicine and Arthroscopy Review
https://www.readbyqxmd.com/read/29093428/danshen-attenuates-cartilage-injuries-in-osteoarthritis-in-vivo-and-in-vitro-by-activating-jak2-stat3-and-akt-pathways
#6
Xilin Xu, Hang Lv, Xiaodong Li, Hui Su, Xiaofeng Zhang, Jun Yang
Articular cartilage degradation is a main feature of osteoarthritis (OA). The effects of Danshen, a traditional Chinese herb, in mitigating cartilage damage have been reported before. This study was conducted to investigate the effects of Danshen on cartilage injuries in OA. Rabbit OA models were established by surgical destabilization of the medial meniscus and the anterior and posterior cruciate ligaments in the left knee joint. Injection of Danshen into the articular cavity attenuated OA cartilage destruction in vivo...
October 31, 2017: Experimental Animals
https://www.readbyqxmd.com/read/29075523/standards-for-musculoskeletal-ultrasound
#7
REVIEW
Zbigniew Czyrny
Ultrasound has become the primary diagnostic tool in traumatic, inflammatory and degenerative soft tissue conditions. It is also used to monitor the condition of joints, ligaments, cartilage and muscles. Its widespread availability as well as cases of unsatisfactory quality of equipment and the lack of appropriate training of ultrasound examiners are reasons why standards need to be set for equipment requirements, the scope of ultrasound assessment and examiner's experience. The paper discusses ultrasound criteria that are common for many specialties as well as detailed criteria for the examined regions and structures along with their description...
September 2017: Journal of Ultrasonography
https://www.readbyqxmd.com/read/29071123/treatment-of-scapholunate-ligament-injury-current-concepts
#8
Jonny K Andersson
Injuries to the scapholunate joint are the most common cause of carpal instability.An isolated injury to the scapholunate ligament may progress to abnormal joint mechanics and degenerative cartilage changes.Treatment for scapholunate instability is aimed at arresting the degenerative process by restoring ligament continuity and normalising carpal kinematics.Early arthroscopic diagnosis of scapholunate injury is mandatory for establishing the prognosis of the injury, as a proper ligament repair is recommended within four to six weeks after trauma...
September 2017: EFORT open reviews
https://www.readbyqxmd.com/read/29070587/ghrelin-protects-against-osteoarthritis-through-interplay-with-akt-and-nf-%C3%AE%C2%BAb-signaling-pathways
#9
Ruize Qu, Xiaomin Chen, Wenhan Wang, Cheng Qiu, Miaomiao Ban, Linlin Guo, Krasimir Vasilev, Jianying Chen, Weiwei Li, Yunpeng Zhao
Osteoarthritis (OA) is a common chronic degenerative disease characterized by degeneration in the joints and subsequent destruction of cartilage and bone, yet much remains to be elucidated regarding its molecular mechanism. Ghrelin is a recently discovered neuropeptide with anti-inflammatory actions, but it is unknown whether ghrelin is involved in OA. Human primary chondrocyte and cartilage samples were collected from patients with OA, and the expression pattern of ghrelin was assessed. Human chondrocyte and cartilage samples were stimulated with IL-1β and TNF-α, and exogenous ghrelin-alleviated disorganization of catabolism and anabolism were mediated by IL-1β and TNF-α...
October 25, 2017: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
https://www.readbyqxmd.com/read/29065630/influence-of-gait-speeds-on-contact-forces-of-lower-limbs
#10
Xin Wang, Yue Ma, Bo Yi Hou, Wing-Kai Lam
While walking with fast speed aims to promote health and fitness of individuals, the potential risk on lower limb joint loading across walking speed is still unknown. In order to determine the joint contact force loading associated with different walking speeds, fifteen young male and fifteen female participants performed barefoot walking across different speeds (regular = 1.1 m/s, medium = 1.4 m/s, and fast = 1.7 m/s). The synchronized motion and ground reaction force (GRF) data were captured by Codamotion capture system and AMTI force platform...
2017: Journal of Healthcare Engineering
https://www.readbyqxmd.com/read/29030067/adipose-tissue-derived-stem-cells-in-combination-with-xanthan-gum-attenuate-osteoarthritis-progression-in-an-experimental-rat-model
#11
Li Mei, Bojiang Shen, Jiajun Xue, Shaoying Liu, Aibin Ma, Fuyan Liu, Huarong Shao, Jianying Chen, Qixin Chen, Fei Liu, Yong Ying, Peixue Ling
The current study explored the efficacy of an intra-articular (IA) injection of allogeneic adipose tissue-derived stem cells (ADSCs) combined with xanthan gum (XG) in a rat osteoarthritis (OA) model. We confirmed that XG significantly inproved proliferation of ADSCs in a dose dependent manner in vitro. The rat OA model was induced by an anterior cruciate ligament transection (ACLT), and at 4 weeks after surgery, rats were divided into four groups: the XG-ADSCs group, the ADSCs group, the XG group and the phosphate-buffered saline (PBS) group...
December 9, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/29020880/pulsed-electromagnetic-fields-and-tissue-engineering-of-the-joints
#12
Kenjiro Iwasa, A Hari Reddi
BACKGROUND: Bone and joint formation, maintenance, and regeneration are regulated by both chemical and physical signals. Among the physical signals there is an increasing realization of the role of pulsed electromagnetic fields (PEMF) in the treatment of nonunions of bone fractures. The discovery of the piezoelectric properties of bone by Fukada and Yasuda in 1953 in Japan established the foundation of this field. Pioneering research by Bassett and Brighton and their teams resulted in the approval by the Food and Drug Administration (FDA) of the use of PEMF in the treatment of fracture healing...
November 17, 2017: Tissue Engineering. Part B, Reviews
https://www.readbyqxmd.com/read/29020716/improving-joint-pain-and-function-in-osteoarthritis
#13
REVIEW
Claire Owens, Philip G Conaghan
Osteoarthritis has become a major chronic pain condition. It affects more than 10% of adults and accounts for almost 10% of health service resources. The impact of osteoarthritis is amplified by underuse of effective muscle strengthening exercises and a focus on often less effective and poorly tolerated analgesic therapies. Although traditionally considered to be primarily a disease of cartilage, there is now ample evidence that typical clinical osteoarthritis involves multiple tissue pathologies. Increased BMI is associated with a higher incidence of knee osteoarthritis...
December 2016: Practitioner
https://www.readbyqxmd.com/read/28991041/quadriceps-function-and-knee-joint-ultrasonography-following-acl-reconstruction
#14
Derek N Pamukoff, Melissa M Montgomery, Tyler J Moffit, Michael N Vakula
PURPOSE: Individuals with anterior cruciate ligament reconstruction (ACLR) are at greater risk for knee osteoarthritis (OA), partially due to chronic quadriceps dysfunction. Articular cartilage is commonly assessed using magnetic resonance imaging and radiography, but these methods are expensive and lack portability. Ultrasound imaging may provide a cost-effective and portable alternative for imaging the femoral cartilage. The purpose of this study was to compare ultrasonography of the femoral cartilage between the injured and uninjured limbs of individuals with unilateral ACLR, and to examine the association between quadriceps function and ultrasonographic measures of femoral cartilage...
October 3, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28989937/comparison-of-2-radiographic-techniques-for-measurement-of-tibiofemoral-joint-space-width
#15
Nabil Mehta, Jeffrey Duryea, Gary J Badger, Matthew R Akelman, Morgan H Jones, Kurt P Spindler, Braden C Fleming
BACKGROUND: No consensus is available regarding the best method for measuring tibiofemoral joint space width (JSW) on radiographs to quantify joint changes after injury. Studies that track articular cartilage thickness after injury frequently use patients' uninjured contralateral knees as controls, although the literature supporting this comparison is limited. PURPOSE: (1) To compare JSW measurements using 2 established measurement techniques in healthy control participants and (2) to determine whether the mean JSW of the uninjured contralateral knee in a cohort with anterior cruciate ligament (ACL) reconstruction is different from that obtained from a true control population...
September 2017: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/28989151/-application-of-pie-crusting-the-medial-collateral-ligament-release-in-arthroscopic-surgery-for-posterior-horn-of-%C3%A2-medial-meniscus-in-knee-joint
#16
Weihong Zhu, Qi Tang, Lele Liao, Ding Li, Yang Yang, You Chen
To explore the effectiveness and safety of pie-crusting the medial collateral ligament release (MCL) in treating posterior horn of medial meniscus (PHMM) tear in tight medial tibiofemoral compartment of knee joint.
 Methods: Thirty-two consecutive patients with PHMM tear in tight medial tibiofemoral compartment of knee joint were admitted to our department from January, 2013 to December, 2014. All patients were performed pie-crusting the MCL release at its tibial insertion with 18-gauge intravenous needle...
September 28, 2017: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
https://www.readbyqxmd.com/read/28987873/hip-joint-biomechanics-in-those-with-and-without-post-traumatic-knee-osteoarthritis-after-anterior-cruciate-ligament-injury
#17
E Wellsandt, J A Zeni, M J Axe, L Snyder-Mackler
BACKGROUND: Anterior cruciate ligament injury results in altered kinematics and kinetics in the knee and hip joints that persist despite surgical reconstruction and rehabilitation. Abnormal movement patterns and a history of osteoarthritis are risk factors for articular cartilage degeneration in additional joints. The purpose of this study was to determine if hip joint biomechanics early after anterior cruciate ligament injury and reconstruction differ between patients with and without post-traumatic knee osteoarthritis 5years after reconstruction...
October 2, 2017: Clinical Biomechanics
https://www.readbyqxmd.com/read/28986634/contrast-enhanced-mri-findings-of-the-knee-in-healthy-children-establishing-normal-values
#18
Robert Hemke, J Merlijn van den Berg, Charlotte M Nusman, E Charlotte van Gulik, Anouk M Barendregt, Dieneke Schonenberg-Meinema, Koert M Dolman, Taco W Kuijpers, Mario Maas
OBJECTIVES: To define normative standards for the knee in healthy children using contrast-enhanced MRI, focusing on normal synovial membrane thickness. Secondly, presence of joint fluid and bone marrow oedema was evaluated. METHODS: For this study, children without disorders potentially resulting in (accompanying) arthritis were included. Patients underwent clinical assessments, followed by contrast-enhanced MRI. MRI features were evaluated in consensus using the Juvenile Arthritis MRI Scoring (JAMRIS) system...
October 6, 2017: European Radiology
https://www.readbyqxmd.com/read/28970982/concomitant-reverse-hill-sachs-lesion-and-posterior-humeral-avulsion-of-the-glenohumeral-ligament-treatment-with-fresh-talus-osteochondral-allograft-and-arthroscopic-posterior-humeral-avulsion-of-the-glenohumeral-ligament-and-labrum-repair
#19
Justin J Mitchell, Alexander R Vap, George Sanchez, Daniel J Liechti, Jorge Chahla, Gilbert Moatshe, Márcio B Ferrari, Matthew T Provencher
Chronic posterior glenohumeral joint instability can be a challenging clinical entity for patients and surgeons alike. In the setting of a posterior dislocation, a large anterior humeral impaction injury (reverse Hill-Sachs [HS]) may occur, leading to engagement of the humerus with the posterior glenoid bone, especially during internal rotation of the joint. A reverse HS is especially debilitating because of the significant portion of affected humeral head cartilage, and is made worse in the setting of ligamentous disruption such as a posterior humeral avulsion of the glenohumeral ligament (HAGL) lesions...
August 2017: Arthroscopy Techniques
https://www.readbyqxmd.com/read/28965577/effects-of-biological-factors-and-health-condition-on-mercury-and-selenium-concentrations-in-the-cartilage-meniscus-and-anterior-cruciate-ligament
#20
Danuta I Kosik-Bogacka, Natalia Lanocha-Arendarczyk, Karolina Kot, Zaneta Ciosek, Pawel Zietek, Maciej Karaczun, Bogumila Pilarczyk, Agnieszka Tomza-Marciniak, Joanna Podlasinska, Elzbieta Kalisinska, Joanna Pyzia
Due the long-term nature of joint tissue remodeling processes, knee structures including meniscus and anterior cruciate ligament (ACL) can be a model for studying the bioaccumulation of mercury (Hg) and selenium (Se). The accumulation and retention of Hg in human tissues can have a negative effect on the proper functioning of homeostasis-affecting organisms. A factor of chronic poisoning with Hg forms is probably the Se:Hg ratio in tissues. Se:Hg molar ratios below one may increase Hg toxicity potentials, while molar ratios that approach or exceed one effectively may protect against Hg toxicity...
December 2017: Journal of Trace Elements in Medicine and Biology
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