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Cardiac resynchronization

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https://www.readbyqxmd.com/read/28814710/left-univentricular-pacing-by-rate-adaptive-atrioventricular-delay-in-treatment-of-chronic-heart-failure
#1
Lulu Zhao, Ling Zhao, Lijin Pu, Baotong Hua, Yu Wang, Shumin Li, Qing Li, Tao Guo
BACKGROUND Cardiac resynchronization therapy (CRT) is efficacious in the treatment of chronic heart failure (CHF); however, because it is non-physiological, some patients are unresponsive. The present study used rate-adaptive atrioventricular delay (RAAVD) to track the physiological atrioventricular delay and investigated the effects of left univentricular pacing on CRT. MATERIAL AND METHODS Patients with CHF fulfilling the indication of CRT Class I were categorized into a left univentricular pacing by RAAVD group and a standard biventricular pacing group...
August 17, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28814264/left-ventricular-contractile-reserve-by-stress-echocardiography-as-a-predictor-of-response-to-cardiac-resynchronization-therapy-in-heart-failure-a-systematic-review-and-meta-analysis
#2
Quirino Ciampi, Clara Carpeggiani, Claudio Michelassi, Bruno Villari, Eugenio Picano
BACKGROUND: The presence of left ventricular contractile reserve (LVCR) during stress echo (SE) may provide favorable response to cardiac resynchronization therapy (CRT) in heart failure patients. The aim of the study was to perform a meta-analysis of available SE data in this set of patients. METHODS: From a Pubmed and Advance Google Scholar database web based search scan up to December 2016, we initially identified 5906 records. From this initial set, we removed that did not include SE and duplicate studies...
August 16, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28805992/a-brief-overview-of-cardiac-resynchronization-therapy-and-its-current-use-in-clinical-practice
#3
EDITORIAL
Luigi Tavazzi
No abstract text is available yet for this article.
August 14, 2017: European Journal of Heart Failure
https://www.readbyqxmd.com/read/28803515/protocol-driven-remote-monitoring-of-cardiac-resynchronization-therapy-as-part-of-a-heart-failure-disease-management-strategy
#4
Christophe J P Smeets, Frederik H Verbrugge, Julie Vranken, Jo Van der Auwera, Wilfried Mullens, Matthias Dupont, Lars Grieten, Hélène De Cannière, Dorien Lanssens, Thijs Vandenberk, Valerie Storms, Inge M Thijs, Pieter Vandervoort
BACKGROUND: Cardiac resynchronisation therapy (CRT) is an established treatment for heart failure (HF) with reduced ejection fraction. CRT devices are equipped with remote monitoring functions, which are pivotal in the detection of device problems, but may also facilitate disease management. The aim of this study was to provide a comprehensive overview of the clinical interventions taken based on remote monitoring. METHODS: This is a single centre observational study of consecutive CRT patients (n = 192) participating in protocol-driven remote follow-up...
August 14, 2017: Acta Cardiologica
https://www.readbyqxmd.com/read/28803216/3d-2d-registration-with-superabundant-vessel-reconstruction-for-cardiac-resynchronization-therapy
#5
Daniel Toth, Maria Panayiotou, Alexander Brost, Jonathan M Behar, Christopher A Rinaldi, Kawal S Rhode, Peter Mountney
A key component of image guided interventions is the registration of preoperative and intraoperative images. Classical registration approaches rely on cross-modality information; however, in modalities such as MRI and X-ray there may not be sufficient cross-modality information. This paper proposes a fundamentally different registration approach which uses adjacent anatomical structures with superabundant vessel reconstruction and dynamic outlier rejection. In the targeted clinical scenario of cardiac resynchronization therapy (CRT) delivery, preoperative, non contrast-enhanced, MRI is registered to intraoperative, contrasted X-ray fluoroscopy...
August 5, 2017: Medical Image Analysis
https://www.readbyqxmd.com/read/28801203/echocardiographic-prediction-of-cardiac-resynchronization-therapy-response-requires-analysis-of-both-mechanical-dyssynchrony-and-right-ventricular-function-a-combined-analysis-of%C3%A2-patient-data-and-computer-simulations
#6
Wouter M van Everdingen, John Walmsley, Maarten J Cramer, Iris van Hagen, Bart W L De Boeck, Mathias Meine, Tammo Delhaas, Pieter A Doevendans, Frits W Prinzen, Joost Lumens, Geert E Leenders
BACKGROUND: Pronounced echocardiographically measured mechanical dyssynchrony is a positive predictor of response to cardiac resynchronization therapy (CRT), whereas right ventricular (RV) dysfunction is a negative predictor. The aim of this study was to investigate how RV dysfunction influences the association between mechanical dyssynchrony and left ventricular (LV) volumetric remodeling following CRT. METHODS: One hundred twenty-two CRT candidates (mean LV ejection fraction, 19 ± 6%; mean QRS width, 168 ± 21 msec) were prospectively enrolled and underwent echocardiography before and 6 months after CRT...
August 8, 2017: Journal of the American Society of Echocardiography
https://www.readbyqxmd.com/read/28798987/maximization-of-interventricular-conduction-time-by-means-of-quadripolar-leads-for-cardiac-resynchronization-therapy
#7
Giuseppe Stabile, Valter Bianchi, Francesco Solimene, Assunta Iuliano, Quintino Parisi, Patrizia Pepi, Mario Bocchiardo, Francesco Urraro, Antonio De Simone, Roberto Ospizio, Antonio D'Onofrio
PURPOSE: Identifying the left ventricular (LV) site associated with the maximum spontaneous interventricular conduction time (right ventricle (RV)-to-LV interval) has proved to be an effective strategy for optimal LV pacing site selection in cardiac resynchronization therapy (CRT). The aim of our study was to determine whether quadripolar LV lead technology allows RV-to-LV interval maximization. METHODS: We enrolled 108 patients undergoing implantation of a CRT system using an LV quadripolar lead and 114 patients who received a bipolar lead...
August 10, 2017: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
https://www.readbyqxmd.com/read/28794367/earlier-right-ventricular-pacing-in-cardiac-resynchronization-therapy-for-a-patient-with-right-axis-deviation
#8
Yusuke Hattori, Kohei Ishibashi, Takashi Noda, Hideo Okamura, Hideaki Kanzaki, Toshihisa Anzai, Satoshi Yasuda, Kengo Kusano
We describe the case of a 37-year-old woman who presented with complete right bundle branch block and right axis deviation. She was admitted to our hospital due to severe heart failure and was dependent on inotropic agents. Cardiac resynchronization therapy was initiated but did not improve her condition. After the optimization of the pacing timing, we performed earlier right ventricular pacing, which led to an improvement of her heart failure. Earlier right ventricular pacing should be considered in patients with complete right bundle branch block and right axis deviation when cardiac resynchronization therapy is not effective...
August 10, 2017: Internal Medicine
https://www.readbyqxmd.com/read/28793004/abnormal-diastolic-function-underlies-the-different-beneficial-effects-of-cardiac-resynchronization-therapy-on-ischemic-and-non-ischemic-cardiomyopathy
#9
Qi Wang, Kang-Yu Chen, Fei Yu, Hao Su, Chun-Sheng An, Yang Hu, Dong-Mei Yang, Jian Xu, Ji Yan
OBJECTIVES: To investigate the association between diastolic function and the different beneficial effects of cardiac resynchronization therapy in patients with heart failure due to different causes. METHODS: The 104 enrolled patients were divided into an ischemic cardiomyopathy group (n=27) and a non-ischemic cardiomyopathy group (n=77) according to the cause of heart failure. Before implantation, left ventricular diastolic function was evaluated in all patients using echocardiography...
July 2017: Clinics
https://www.readbyqxmd.com/read/28791621/assessment-of-dyssynchrony-by-gated-myocardial-perfusion-imaging-does-not-improve-patient-management
#10
Ran Lee, Ravi V Shah, Venkatesh L Murthy
Clinical trials have demonstrated improved outcomes with cardiac resynchronization therapy in patients with heart failure and electrical evidence of dyssynchrony. There has been intense effort at developing imaging markers of dyssynchrony with the aim of improved risk stratification. However, these efforts have not been fruitful to date. This article discusses mechanisms of cardiac dyssynchrony, reviews clinical data supporting resynchronization therapy, and addresses the lack of convincing evidence to support the use of noninvasive imaging measures of dyssynchrony in improving patient management...
August 8, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28781300/successful-catheter-ablation-as-a-substitute-for-cardiac-resynchronization-therapy-in-patient-with-an-accessory-pathway-induced-cardiomyopathy
#11
Keisuke Nakabayashi, Ryo Sugiura, Yusuke Mizuno, Hiroko Kato, Naomi Nakazawa, Toshiaki Suzuki, Hideki Saito, Naomi Kawakatsu, Masayuki Goto, Daichi Isomura, Hisayuki Okada, Toshiaki Oka
A 50-year-old man presented with exertional dyspnea and orthopnea. An electrocardiogram showed a delta wave and a wide QRS complex, similar to left bundle branch block. Cardiac echocardiography revealed diffuse severe hypokinesis and dyssynchrony. The patient was diagnosed with congestive heart failure. We considered that the patient's condition was caused by an accessory pathway-induced cardiomyopathy after heart failure compensation with guideline-oriented medical therapy. We therefore performed catheter ablation for right-sided pre-excitation syndrome as cardiac resynchronization therapy...
August 1, 2017: Internal Medicine
https://www.readbyqxmd.com/read/28780194/scar-characterization-to-predict-life-threatening-arrhythmic-events-and%C3%A2-sudden-cardiac-death-in-patients-with-cardiac-resynchronization-therapy-the-gaudi-crt-study
#12
Juan Acosta, Juan Fernández-Armenta, Roger Borràs, Ignasi Anguera, Felipe Bisbal, Julio Martí-Almor, Jose M Tolosana, Diego Penela, David Andreu, David Soto-Iglesias, Reinder Evertz, María Matiello, Concepción Alonso, Roger Villuendas, Teresa M de Caralt, Rosario J Perea, Jose T Ortiz, Xavier Bosch, Luis Serra, Xavier Planes, Andreas Greiser, Okan Ekinci, Luis Lasalvia, Lluis Mont, Antonio Berruezo
OBJECTIVES: The aim of this study was to analyze whether scar characterization could improve the risk stratification for life-threatening ventricular arrhythmias and sudden cardiac death (SCD). BACKGROUND: Among patients with a cardiac resynchronization therapy (CRT) indication, appropriate defibrillator (CRT-D) therapy rates are low. METHODS: Primary prevention patients with a class I indication for CRT were prospectively enrolled and assigned to CRT-D or CRT pacemaker according to physician's criteria...
July 28, 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28776898/august-2017-at-a-glance-tailored-treatment-acute-heart-failure-and-cardiac-resynchronization
#13
Marco Metra
No abstract text is available yet for this article.
August 2017: European Journal of Heart Failure
https://www.readbyqxmd.com/read/28772031/local-microrna-133a-downregulation-is-associated-with-hypertrophy-in-the-dyssynchronous-heart
#14
Lars B van Middendorp, Marion Kuiper, Chantal Munts, Philippe Wouters, Jos G Maessen, Frans A van Nieuwenhoven, Frits W Prinzen
AIMS: Left bundle branch block (LBBB) creates considerable regional differences in mechanical load within the left ventricle (LV). We investigated expression of selected microRNAs (miRs) in relation to regional hypertrophy and fibrosis in LBBB hearts and their reversibility upon cardiac resynchronization therapy (CRT). METHODS AND RESULTS: Eighteen dogs were followed for 4 months after induction of LBBB, 10 of which received CRT after 2 months. Five additional dogs served as control...
August 2017: ESC Heart Failure
https://www.readbyqxmd.com/read/28770034/echocardiographic-electrocardiographic-changes-and-clinical-outcomes-of-patients-who-respond-to-cardiac-resynchronization-therapy-after-one-year
#15
Young Choi, Jaeho Byeon, Mi-Hyang Jung, Hae Ok Jung, Ho-Joong Youn
BACKGROUND: Response to cardiac resynchronization therapy (CRT) is commonly assessed after 6 or 12 months. We evaluated subsequent echocardiographic changes, serial QRS duration, and clinical outcomes in patients showing delayed responses to CRT after 12 months. METHODS: Among all patients who received CRT in Seoul St. Mary's Hospital, 36 one-year survivors were enrolled. Indicators of a positive CRT response were ≥ 15% reduction in left ventricular end-systolic volume (LVESV) or ≥ 10% increase in left ventricular ejection fraction (LVEF) on any follow up echocardiogram...
June 2017: Journal of Cardiovascular Ultrasound
https://www.readbyqxmd.com/read/28765767/simple-and-effective-solution-for-diaphragm-pacing-by-that-uses-the-transvenous-femoral-approach-in-a-patient-treated-with-cardiac-resynchronization-defibrillator-therapy-the-wrapping-method
#16
Ahmet Taha Alper, Mert İlker Hayıroğlu, Ahmet İlker Tekkeşin, Ceyhan Türkkan
The use of cardiac resynchronization therapy (CRT) has become widespread in patients with heart failure who meet the criteria for implantation. Coronary sinus lead positioning is important to provide the intended biventricular stimulation. Diaphragm pacing is a lead-related complication which occurs secondary to phrenic nerve stimulation. We present the case of a 58-year-old male patient who had diaphragm pacing after CRT with defibrillator implantation. The complication was resolved by using the transvenous femoral approach with the wrapping method...
August 2017: Journal of Arrhythmia
https://www.readbyqxmd.com/read/28765745/rapid-and-potent-antiarrhythmic-effect-of-cardiac-resynchronization-therapy-in-a-patient-with-advanced-dilated-cardiomyopathy-and-a-large-ventricular-arrhythmia-burden
#17
Dong Sub Jeon, Jong Sung Park
We report a case demonstrating a rapid and potent antiarrhythmic effect of biventricular pacing. A 67-year-old male patient with dilated cardiomyopathy was admitted for heart failure. The initial surface electrocardiogram revealed a left bundle branch block with a QRS complex duration of 200 ms. Echocardiographic examination revealed a left ventricular ejection fraction of 16%, a left ventricular end-diastolic dimension of 91 mm, and marked interventricular dyssynchrony. Continuous rhythm monitoring revealed frequently-recurring non-sustained monomorphic ventricular tachycardia (VT)...
July 2017: Korean Circulation Journal
https://www.readbyqxmd.com/read/28762918/-noninvasive-electrophysiological-mapping-in-patients-with-complete-left-bundle-branch-block-and-different-modes-of-biventricular-pacing
#18
S V Zubarev, M P Chmelevsky, M A Budanova, M A Trukshina, T A Lyubimtseva, V K Lebedeva, D S Lebedev
OBJECTIVE: to investigate possibilities of noninvasive electrophysiological mapping (NEM) during biventricular (BiV) pacing and to compare the results with data of 12 lead ECG and tissue Doppler echocardiography (TDI). MATERIAL AND METHODS: The study included 25 patients with complete left bundle branch block (LBBB) and implanted cardiac resynchronization therapy (CRT) system. Twenty-two patients were CRT responders, three other patients did not demonstrate a clear effect...
May 2017: Kardiologiia
https://www.readbyqxmd.com/read/28760213/retained-cardiac-implantable-electronic-device-fragments-are-not-associated-with-magnetic-resonance-imaging-safety-issues-morbidity-or-mortality-after-orthotopic-heart-transplant
#19
Christopher O Austin, Kevin Landolfo, Pragnesh P Parikh, Parag C Patel, K L Venkatachalam, Fred M Kusumoto
BACKGROUND: Cardiac implantable electronic device therapy (CIED) has revolutionized treatment for advanced heart failure. Most patients considered for orthotopic heart transplantation (OHT) are treated with implantable cardioverter defibrillators, cardiac resynchronization therapy, or both. These CIEDs are surgically extracted at the time of transplant. Occasionally, CIEDs are incompletely removed. Little is known about the outcomes of post-OHT patients with retained CIED fragments. METHODS: We identified 200 consecutive patients that underwent OHT at our institution between April 2006 and December 2014 and performed a retrospective analysis of available radiographic images and clinical records...
August 2017: American Heart Journal
https://www.readbyqxmd.com/read/28757175/-main-novelties-of-the-last-set-of-european-guidelines-for-the-management-of-heart-failure
#20
Richard Isnard, Nadjib Hammoudi, Lise Legrand, Françoise Pousset
Heart failure is the main chronic disease in cardiology. Its prognosis remains poor despite improvements in its management that allow patients to live increasingly longer with this disease, alternating periods of stability and episodes of decompensation. Treatment guidelines are regularly updated to integrate new results of recent trials that are likely to influence routine care. These guidelines are proposed with different classes of recommendations and difference levels of evidence. It is of paramount importance to summarize the guidelines to make them accessible to the vast majority of cardiologists and easier to read to promote their application...
July 27, 2017: La Presse Médicale
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