keyword
https://read.qxmd.com/read/38357954/gas-chromatography-mass-spectrometry-gc-ms-analysis-of-scaphium-affine-seed-extract-and-assessment-of-its-anti-hemorrhoidal-efficacy
#21
JOURNAL ARTICLE
Syed Atif Abbas, Abdullah Khan, Mehraj Fatima, Anandarajagopal Kalusalingam, Mahibub Mahamadsa Kanakal, Shiva Kumar Inamdar, Vijay Kotra, Long Chiau Ming, Ashok Kumar M Dastapur, Tazneem B
BACKGROUND: Seeds of plant Scaphium Affine are traditionally used by the healers of "India" for the treatment of piles. OBJECTIVE: The primary objective of the study was to assess the anti-hemorrhoidal potential of the ethanolic seed extract of Scaphium affine. METHODS: After the soxhlet extraction method, the seed extract from Scaphium affine was first submitted to phytochemical standardization and then GC-MS analysis. Rats were given Croton oil and Jatropha oil to develop hemorrhoids, and Scaphium affine seed extract (ESA) was administered orally for 5 days and 3 days, respectively, at doses of 1000 and 500 mg/kg...
February 14, 2024: Anti-inflammatory & Anti-allergy Agents in Medicinal Chemistry
https://read.qxmd.com/read/38357940/clinical-outcomes-before-and-after-prucalopride-treatment-an-observational-study-in-patients-with-chronic-idiopathic-constipation-in-the-usa
#22
JOURNAL ARTICLE
Anthony Lembo, Brooks D Cash, Mei Lu, Emi Terasawa, Brian Terreri, Shawn Du, Rajeev Ayyagari, Paul Feuerstadt, Baharak Moshiree, Ben Westermeyer, Selina Pi, Mena Boules
INTRODUCTION: This real-world US-based claims study compared constipation-related symptoms and complications 6 months before and after prucalopride initiation in adults with chronic idiopathic constipation (CIC). METHODS: This observational, retrospective cohort analysis used the IBM MarketScan® Commercial Claims and Encounters and the Medicare Supplemental databases (January 2015-June 2020). Prucalopride-treated patients (≥18 years old) who had ≥1 constipation-related International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) diagnosis code during the baseline or study period were included...
February 15, 2024: Clinical and Translational Gastroenterology
https://read.qxmd.com/read/38356039/clinical-evidence-and-rationale-of-mesoglycan-to-treat-chronic-venous-disease-and-hemorrhoidal-disease-a-narrative-review
#23
REVIEW
Gaetano Gallo, Arcangelo Picciariello, Antonella Tufano, Giuseppe Camporese
Chronic venous disease (CVD) and hemorrhoidal disease (HD) are among the most common vascular diseases in the world, with CVD affecting 22-41% of the population in Europe and HD having a point prevalence of 11-39%. The burden is substantial in terms of the effect of symptoms on patients' health-related quality of life (HRQoL) and direct/indirect medical costs. Treatment begins with lifestyle changes, compression in CVD and topical therapies in HD, and escalates as needed through oral therapies first and eventually to surgery for severe disease...
February 14, 2024: Updates in Surgery
https://read.qxmd.com/read/38354383/a-rare-case-of-varicella-zoster-infection-in-hemorrhoids-in-a-patient-with-inflammatory-bowel-disease
#24
JOURNAL ARTICLE
Hanna Siatecka, Sarah Al-Awami, Ahsan Siddiqi, A Hafeez Diwan
Hemorrhoids are normal anatomical structures in the anus. When symptomatic, they prompt medical attention due to pain, rectal bleeding, and discomfort. Treatment includes dietary modifications, rubber band ligations, sclerotherapy, cryotherapy, or hemorrhoidectomy. Histologic examination is important to rule out incidental findings, such as perianal intraepithelial neoplasia, anal carcinoma, melanoma, or coexisting infections. Special attention should be given when patient is immunocompromised. We present a case of a 41-year-old man with a history of ulcerative colitis on adalimumab who presented with anal lesions...
March 1, 2024: American Journal of Dermatopathology
https://read.qxmd.com/read/38345506/anorectal-melanoma-a-rare-entity
#25
JOURNAL ARTICLE
Luís Miguel Relvas, Tânia Gago, Francisco Velasco, Sónia Barros, Isabel Carvalho, Paulo Caldeira
Anorectal melanoma is a rare malignant tumor with the potential of simulating a benign anorectal disease, making its diagnosis difficult. We describe a case of anorectal melanoma, in which the interpretation of symptoms as hemorrhoidal disease delayed diagnosis and appropriate intervention.
February 12, 2024: Revista Española de Enfermedades Digestivas
https://read.qxmd.com/read/38330500/evaluation-of-a-novel-disposable-endoscope-for-retroflexed-endoscopic-rubber-band-ligation-of-internal-hemorrhoids-a-randomized-pilot-study
#26
JOURNAL ARTICLE
Wen Xu, Guili Xia, Laihe Li, Ge Cao, Xianhuan Yan, Ling Dong, Ying Zhu
PURPOSE: Retroflexed endoscopic rubber band ligation (ERBL) for treating Grade II and III internal hemorrhoids using disposable endoscopes has not been previously assessed. We therefore compared the safety and effectiveness of ERBL for internal hemorrhoids using novel disposable endoscopes versus traditional reusable endoscopes. METHODS: This prospective randomized controlled trial involved 42 patients who underwent ERBL for Grade II and III internal hemorrhoids using either a disposable endoscope (n = 21) or a reusable endoscope (n = 21)...
February 8, 2024: Postgraduate Medical Journal
https://read.qxmd.com/read/38322778/use-of-rectal-balloon-spacer-in-patients-with-localized-prostate-cancer-receiving-external-beam-radiotherapy
#27
JOURNAL ARTICLE
Paulo Costa, Joana Vale, Graça Fonseca, Adelina Costa, Michael Kos
OBJECTIVE: To evaluate the efficacy of the balloon spacer when used to reduce the radiation dose delivered to the rectum in prostate cancer patients undergoing external beam radiotherapy. METHOD: A single center retrospective analysis including 75 PC patients with localized T1-T3a disease who received balloon spacer followed by EBRT. Pre- and post-implantation computed tomography (CT) scans were utilized for treatment planning for standard EBRT (78-81 Gy in 1...
March 2024: Technical innovations & patient support in radiation oncology
https://read.qxmd.com/read/38318578/prevalence-of-hemorrhoids-and-the-associated-risk-factors-among-the-general-adult-population-in-makkah-saudi-arabia
#28
JOURNAL ARTICLE
Raghad O Al-Masoudi, Raghad Shosho, Dhuha Alquhra, Mohammed Alzahrani, Mohanned Hemdi, Lujain Alshareef
INTRODUCTION: Hemorrhoidal disease is one of the most common benign anorectal conditions. It is described as the symptomatic enlargement and abnormally downward displacement of anal cushions. Its effect on the quality of life of patients is significantly negative and is considered one of the leading causes of lower gastrointestinal bleeding. However, studies that determine the prevalence of and risk factors associated with hemorrhoidal disease are limited...
January 2024: Curēus
https://read.qxmd.com/read/38301138/efficacy-of-individualized-homeopathic-medicines-in-the-treatment-of-hemorrhoids-double-blind-randomized-placebo-controlled-trial
#29
JOURNAL ARTICLE
Munmun Koley, Vinod Kumar Vimal, Arvind Kumar Verma, Shiv Shanker Pal, Dileep Kumar Sonkar, Smita Vimal, Om Prakash Singh, Shubhamoy Ghosh, Subhranil Saha
Objectives: To investigate the efficacy and safety of individualized homeopathic medicines (IHMs) in treating hemorrhoids compared with placebo. Design: This is a double-blind, randomized (1:1), two parallel arms, placebo-controlled trial. Setting: The trial was conducted at the surgery outpatient department of the State National Homoeopathic Medical College and Hospital, Lucknow, Uttar Pradesh, India. Subjects: Patients were 140 women and men, aged between 18 and 65 years, with a diagnosis of primary hemorrhoids grades I-III for at least 3 months...
February 1, 2024: J Integr Complement Med
https://read.qxmd.com/read/38294832/the-american-society-of-colon-and-rectal-surgeons-clinical-practice-guidelines-for-the-management-of-hemorrhoids
#30
JOURNAL ARTICLE
Alexander T Hawkins, Bradley R Davis, Anuradha R Bhama, Sandy H Fang, Aaron J Dawes, Daniel L Feingold, Amy L Lightner, Ian M Paquette
No abstract text is available yet for this article.
January 31, 2024: Diseases of the Colon and Rectum
https://read.qxmd.com/read/38283447/horseshoe-abscess-as-a-rare-complication-after-transanal-hemorrhoid-dearterialization-with-mucopexy-a-case-report
#31
Yuki Nakao, Heather Reeves, David A Denning, James Martin
Transanal hemorrhoidal dearterialization (THD) is a minimally invasive procedure that has gained popularity as a treatment for symptomatic hemorrhoids. It involves ligating the arterial blood supply to the hemorrhoidal plexus. Compared to conventional ligation or resection, THD is associated with less postoperative bleeding and pain, allowing for same-day surgery discharge. Horseshoe abscess is a rare but known complication of anorectal surgery, characterized by an abscess that extends around the anal canal, often involving the ischiorectal fossa and adjacent structures...
December 2023: Curēus
https://read.qxmd.com/read/38261136/sclerotherapy-for-hemorrhoidal-disease-systematic-review-and-meta-analysis
#32
REVIEW
G Gallo, A Picciariello, C Armellin, E Lori, G Tomasicchio, G L Di Tanna, G A Santoro, M Alharbi, S Sorrenti, U Grossi
BACKGROUND: This systematic review and meta-analysis aimed to evaluate the safety and efficacy of sclerotherapy methods for hemorrhoidal disease (HD) over the past 40 years. METHODS: The review followed the 2020 Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines. A comprehensive literature search was conducted, including studies reporting the use of sclerotherapy in patients with HD. Study eligibility criteria were defined, and data were extracted independently by the authors...
January 23, 2024: Techniques in Coloproctology
https://read.qxmd.com/read/38243976/comprehensive-review-on-the-genus-haloxylon-pharmacological-and-phytochemical-properties
#33
JOURNAL ARTICLE
Smail Amtaghri, Mohamed Eddouks
AIMS: This review aimed to review the biological, pharmacological, and phytochemical aspects of the genus Haloxylon. BACKGROUND: Plants of the genus Haloxylon have been used for a long time in traditional medicine, and they are distributed in the western Mediterranean region to the Middle East, Iran, Mongolia, Burma, and southwest China. The studied parts of Haloxylon species include aerial parts, leaves, branches, seeds, roots, rhizosphere, soil, and whole plants, used to treat several diseases, including sexual disorders, hepatobiliary disorders, eye disorders, skin diseases and hemorrhoids, diarrhea, and effective in the treatment of various ailments such as snake bite, stomach ache, diabetes, wounds, earache and sciatica pain, windbreak dune fixation, feeding of livestock and firewood...
January 15, 2024: Endocrine, Metabolic & Immune Disorders Drug Targets
https://read.qxmd.com/read/38205695/the-lucky-polyp-an-unusual-manifestation-of-chronic-schistosomiasis
#34
JOURNAL ARTICLE
Inês Costa Santos, Sara Ramos Lopes, Madalena Teixeira, Cláudio Martins, Matilde Gonçalves, Ana Luísa Alves
A 23-year-old male from Brazil presented with bright red hematochezia. Proctological examination revealed grade II internal hemorrhoids, but flexible sigmoidoscopy uncovered a 6 mm-pedunculated polyp in the sigmoid colon, which was found to result from inflammatory reaction to Schistosoma mansoni egg deposition. The patient had no signs of portal hypertension and was successfully treated with praziquantel. This case underscores a rare presentation of chronic intestinal schistosomiasis and emphasizes the role of early diagnosis in preventing severe hepatic sequelae of chronic Schistosoma infection...
January 11, 2024: Revista Española de Enfermedades Digestivas
https://read.qxmd.com/read/38162854/colonoscopic-finding-in-children-with-lower-gastrointestinal-complaints
#35
JOURNAL ARTICLE
Shinwari Abdullah Jan, Ghayour Ajmal, Zaheer Naimatullah
BACKGROUND AND AIM: Colonoscopy is an important tool for the diagnosis and treatment of lower gastrointestinal (LGI) diseases in both children and adults. This study describes an endoscopic profile of children at the Shinnwari Gastroenterology Diagnostic Clinic in Jalalabad, Afghanistan. METHODS: This is a cross-sectional descriptive study conducted in children ≤16 years, taken from recorded colonoscopy reports from 1 January 2021 to 30 December 2022...
December 2023: JGH Open: An Open Access Journal of Gastroenterology and Hepatology
https://read.qxmd.com/read/38157069/comparison-between-stapled-hemorrhoidopexy-and-harmonic-scalpel-hemorrhoidectomy-in-the-management-of-third-and-fourth-degree-piles-a%C3%A2-randomized-clinical-trial
#36
JOURNAL ARTICLE
Mohamed Ali Mohamed Nada, Philobater Bahgat Adly Awad, Andrew Morcos Azmy Kirollos, Mostafa Mohamed Abdelaziz, Karim Mohamed Saad Mohamed, Kerolos Bahgat Adly Awad, Basma Hussein Abdelaziz Hassan
BACKGROUND: This study compared the results of stapled hemorrhoidopexy (SH) and harmonic scalpel hemorrhoidectomy (HSH) in the management of grade III and grade IV piles regarding the time of the procedure, postoperative pain, patient satisfaction, wound infection, bleeding, incontinence, and recurrence within 1 year. PATIENTS AND METHODS: This was a single-blind, prospective, randomized, controlled, single-center trial conducted from January to December 2022 that included 50 (68...
December 29, 2023: Chirurgie (Heidelb)
https://read.qxmd.com/read/38152343/editorial-advances-in-proctology-and-colorectal-surgery
#37
EDITORIAL
Marta Goglia, Mario Trompetto, Alberto Realis Luc, Giuseppe Clerico, Gaetano Gallo
No abstract text is available yet for this article.
2023: Frontiers in Surgery
https://read.qxmd.com/read/38152300/the-role-of-pudendal-nerve-block-in-hemorrhoid-surgery-a-systematic-review-and-meta-analysis-of-double-blind-randomized-controlled-trials
#38
Shijun Xia, Lidan Luo, Wenjiang Wu, Kaiyuan Lu, Tao Jiang, Yue Li
BACKGROUND: Pudendal nerve block (PNB) is a commonly used anesthesia method that has been widely used in postoperative analgesia for hemorrhoids in recent years. Therefore, we conducted a systematic review and meta-analysis of double-blind randomized controlled trials (RCTs) to analyze the effectiveness of PNB in postoperative analgesia for hemorrhoids. METHODS: Relevant data and studies published from inception until August 14, 2023, were retrieved from PubMed, Embase, and Web of Science to evaluate the beneficial effects of PNB for analgesia following hemorrhoidectomy...
2023: Frontiers in Medicine
https://read.qxmd.com/read/38151682/thrombosed-external-hemorrhoids-during-pregnancy-surgery-versus-conservative-treatment
#39
JOURNAL ARTICLE
Yuliia Medkova, Inna Tulina, Ivan Novikov, Andrey Nikonov, Anatoliy Ischenko, Leonid Aleksandrov, Donato F Altomare, Agnese Dezi, Arcangelo Picciariello, Petr Tsarkov
The management of thrombosed external hemorrhoids (TEH) during pregnancy is still under debate because of the fear of potential adverse effects on the fetus. This study aims to compare efficacy and safety of conservative versus surgical treatment of acute TEH in pregnant women. Furthermore, the outcome of two different surgical approaches was evaluated. This is a prospective observational study including a sub-analysis on two randomized groups of pregnant women affected by TEH. The primary outcome measured was the impact of conservative and surgical treatment defined in terms of VAS, clinical patient grading assessment scale (CPGAS) and the SF-12 questionnaire...
December 27, 2023: Updates in Surgery
https://read.qxmd.com/read/38131339/stapled-hemorrhoidopexy-a-single-center-study-on-over-600-patients-with-long-term-follow-up
#40
JOURNAL ARTICLE
Levent Eminoğlu
UNLABELLED: OBJECTIVE; The aim of this study is to evaluate the results of patients treated by stapler hemorrhoidopexy for hemorrhoidal disease with a long term foloow up. MATERIAL AND METHOD: Patients who were operated with stapled hemorrhoidopexy (SH) technique between 01/01/2009 and 01/01/2019 in the general surgery department were included. Patients with stage 2 and stage 3 hemorrhoidal disease included. All patients were operated by the same surgeon using a 33-mm circular PPH stapler...
2023: Annali Italiani di Chirurgia
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