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https://www.readbyqxmd.com/read/29749872/secondary-prophylaxis-of-toxoplasmosis-in-pregnancy-in-an-hiv-positive-woman
#1
Subathira Dakshina, Robert F Miller, Cheuk Yw Tong, Liat Sarner
A 39-year-old HIV-positive black African woman with previously treated cerebral toxoplasmosis experienced a foetal intra-uterine death due to congenital toxoplasmosis. This case demonstrates the complexities of screening for maternal toxoplasmosis in the context of pregnancy and HIV infection-related cell-mediated immunosuppression. Additionally, the case highlights the challenges in providing effective preventative and therapeutic drug options for congenital toxoplasmosis.
January 1, 2018: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/29744126/htlv-1-atll-refractory-hypercalcaemia-and-hiv-1-co-infection
#2
Abdullah E Laher, Feroza Motara, Muhammed Moolla, Osman Ebrahim
Adult T-cell lymphoma/leukemia (ATLL) is a rare tumour of T-lymphocytes that is associated with human T-lymphotrophic virus type 1 (HTLV-1) infection as well as severe/refractory hypercalcaemia. Human immunodefficiency virus type 1 (HIV-1) infected individuals are at increased risk of acquiring co-infection with HTLV-1. We present the case of a 37 -year -old HIV-1 positive and antiretroviral therapy naive woman who was admitted to the ICU with delirium, a generalised maculopapular rash, severe hypercalcaemia of 4...
January 2018: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/29736274/burden-of-physical-psychological-and-social-ill-health-during-and-after-pregnancy-among-women-in-india-pakistan-kenya-and-malawi
#3
Mary McCauley, Barbara Madaj, Sarah A White, Fiona Dickinson, Sarah Bar-Zev, Mamuda Aminu, Pamela Godia, Pratima Mittal, Shamsa Zafar, Nynke van den Broek
Introduction: For every woman who dies during pregnancy and childbirth, many more suffer ill-health, the burden of which is highest in low-resource settings. We sought to assess the extent and types of maternal morbidity. Methods: Descriptive observational cross-sectional study at primary-level and secondary-level healthcare facilities in India, Pakistan, Kenya and Malawi to assess physical, psychological and social morbidity during and after pregnancy. Sociodemographic factors, education, socioeconomic status (SES), quality of life, satisfaction with health, reported symptoms, clinical examination and laboratory investigations were assessed...
2018: BMJ Global Health
https://www.readbyqxmd.com/read/29704387/the-crucial-role-of-molecular-testing-to-facilitate-the-diagnosis-of-pneumocystis-pneumonia-during-pregnancy
#4
C H Ding, H Yusoff, N A S Muttaqillah, Y L Tang, T L Tan, P Periyasamy, A Y L Ban
Pneumocystis pneumonia is an important human immunodeficiency virus (HIV)-associated opportunistic infection, and especially so in pregnant HIV-positive patients. We report a case of a 40-year-old woman in her first trimester of pregnancy who initially presented with acute gastroenteritis symptoms but due to a history of high-risk behaviour and the observation of oral thrush, she was worked up for HIV infection. Her retroviral status was positive and her CD4+ T cell count was only 8 cells/µL. She was also worked up for pneumocystis pneumonia due to the presence of mild resting tachypnoea and a notable drop in oxygen saturation (from 100% to 88%) following brief ambulation...
April 2018: Malaysian Journal of Pathology
https://www.readbyqxmd.com/read/29686882/pyosalpinges-after-hysterosalpingography-in-a-patient-with-lower-genital-tract-infection-and-managed-by-laparoscopic-surgery-in-a-resource-low-tertiary-hospital-case-report-and-literature-review
#5
Thomas Obinchemti Egbe, Fidelia Mbi Kobenge, Metogo Mbengono Junette Arlette, Eugene Belley-Priso
Background: Pyosalpinges (a complication of pelvic inflammatory disease) is infection of the fallopian tubes and the morbidity associated with it has major health implications. We are reporting a case of pyosalpinges diagnosed after hysterosalpingography and managed by laparoscopic surgery at the Douala General Hospital, Cameroon. Case presentation: A 29-year-old single woman, an assistant nurse of the Douala tribe in Cameroon. She is G1P0010 and came to our attention because of secondary infertility of three years duration...
2018: Fertility Research and Practice
https://www.readbyqxmd.com/read/29669178/the-utility-of-multiparametric-flow-cytometry-in-the-detection-of-primary-effusion-lymphoma-pel
#6
Jacobo Galán, Isaac Martin, Itziar Carmona, José María Rodriguez-Barbero, Esperanza Cuadrado, Luis García-Alonso, José Antonio García-Vela
Primary effusion lymphoma (PEL) is a rare B cell lymphoproliferative disorder that arises predominantly in body cavities causing malignant effusions.The incidence of PEL is very low, accounting for approximately 4% of all HIV-associated non-Hodgkin lymphomas. PEL has also been described in elderly patients and after solid-organ transplantation. It is associated in all cases with human herpesvirus 8 (HHV8). We describe a case of PEL in a 88-year-old HIV-negative woman who presented with progressive dyspnea and moderate right-sided pleural effusion without significate lymphadenopathies or other effusions...
April 18, 2018: Cytometry. Part B, Clinical Cytometry
https://www.readbyqxmd.com/read/29649980/patterns-of-caesarean-section-in-hiv-infected-and-non-infected-women-in-malawi-is-caesarean-section-used-for-pmtct
#7
Lyson Tenthani, Joep J van Oosterhout, Andreas D Haas, Malango Msukwa, Nozgechi Phiri, Frank Chimbwandira, Kali Tal, Karoline Aebi-Popp, Janne Estill, Olivia Keiser
BACKGROUND: Caesarean section (CS) is not recommended for PMTCT in Malawi HIV Guidelines, contrary to most high-income countries where CS is indicated if viral suppression is sub-optimal pre-delivery. We describe patterns of CS in HIV-infected and uninfected women in Malawi and explored if insight into the use of Elective CS (ECS) for PMTCT could be obtained. METHODS: We used routinely collected data from individual medical records from 17 large health facilities in the central and southern regions of Malawi, from January 2010 to December 2013...
April 12, 2018: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29624560/sexual-behaviors-of-hiv-infected-pregnant-women-and-factors-associated-with-sexual-transmitted-infection-in-south-africa
#8
Dvora Joseph Davey, Remco P H Peters, Noah Kojima, Maanda Mudau, Lindsey De Vos, Dawie Olivier, James A McIntyre, Jeffrey D Klausner, Andrew Medina-Marino
BACKGROUND: Sexual behaviors in HIV-infected pregnant women in South Africa are not well understood. METHODS: HIV-infected pregnant women were recruited into a prospective cohort at first antenatal care visit. Sociodemographic information and self-collected vulvovaginal swab samples were collected from participants. Vulvovaginal swab samples were tested for Chlamydia trachomatis (CT), Neisseria gonorrhoea (NG) and Trichomonas vaginalis (TV) using GeneXpert®. We investigated sexual behaviors, alcohol use and factors associated with condomless sex during pregnancy and prevalent sexually transmitted infection (STI) among our cohort...
April 5, 2018: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/29621948/sinecatechins-10-ointment-for-genital-warts-case-report-of-a-beneficial-reaction-in-an-hiv-positive-woman
#9
Roberta Bilenchi, Marco Campoli, Emanuele Trovato, Elisa Cinotti, Pietro Rubegni, Michele Fimiani
Patients with HIV infection are more likely to develop anogenital warts compared to HIV-negative people and are susceptible to treatment failures and recurrences. We report a case of extensive vulvar warts in an HIV-positive woman successfully treated with sinecatechins ointment. After the failure of a combination of cryotherapy and imiquimod 5% cream, we started therapy with sinecatechins 10% ointment. The patient developed an intense local inflammatory reaction after three weeks that induced the discontinuation of the therapy...
January 1, 2018: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/29610697/a-case-of-spondyloarthritis-in-patient-affected-by-unicentric-castleman-s-disease-effectively-managed-with-surgery-resection-and-tocilizumab-treatment
#10
M Filippini, S Cartella, O Bonzanini, E Morello, A Tincani
A 38-year-old woman was referred to our hospital for rheumatologic manifestations (migrant arthritis and tenosynovitis), without psoriasis or family history of psoriasis, gastroenteric manifestations, or recent genitourinary infections. The instrumental and laboratory tests have suggested a diagnosis of undifferentiated seronegative HLA-B27-positive spondyloarthritis with predominantly peripheral involvement. The symptoms were very severe and resistant to anti-inflammatory drugs and steroids. She had a history of hyaline-vascular unicentric Castleman's disease (HBV, HIV, and HHV-8 negative) treated with surgery resection...
2018: Case Reports in Rheumatology
https://www.readbyqxmd.com/read/29592778/posterior-reversible-encephalopathy-syndrome-in-hiv-positive-patients-a-case-report-and-literature-review
#11
Erica Rm Pool, Michael Porte, Nigel Durham, Sue Urwin, Paul Laboi, Fabiola Martin
We are reporting the case of a woman who was admitted acutely to our intensive care unit without any collateral history. She was diagnosed with posterior reversible encephalopathy syndrome (PRES) as a consequence of poor adherence to anti-hypertensive, anti-diabetic and anti-retroviral medications. PRES is a rare condition, which may cause cortical blindness; contrary to its name it is not always reversible. Rapid diagnosis and aggressive management of underlying causes facilitate reversibility of PRES. We also summarise the literature on patients with HIV and PRES...
January 1, 2018: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/29563125/sequential-retinal-necrosis-secondary-to-varicella-zoster-in-unrecognised-long-standing-hiv-infection-patient-safety-report
#12
Brigid Ky Ning, Simon P Kelly, Celia Chu, Emile Morgan
A retired woman with left ophthalmic shingles of over 2 years' duration attended with bilateral vision loss and systemic upset. Acute retinal necrosis with detachment was detected on right fundus examination. Cataract in left eye precluded funduscopy. Ocular ultrasonography revealed fibrotic retinal detachment in the left eye. MRI brain and orbits also showed signals of retinal detachment. No abnormal MRI signal within the optic nerve or brain was found. Varicella zoster virus was detected in ocular aqueous and blood samples...
March 21, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29514043/-it-is-my-business-a-mixed-methods-analysis-of-covert-contraceptive-use-among-women-in-rakai-uganda
#13
Craig J Heck, Stephanie A Grilo, Xiaoyu Song, Tom Lutalo, Neema Nakyanjo, John S Santelli
OBJECTIVES: Covert contraceptive use (CCU) is the use of family planning without a partner's knowledge. This study sought to examine CCU prevalence among women living in Rakai, Uganda, predictors of CCU, and why women resort to CCU. STUDY DESIGN: We used data from women (15-49years) currently using contraceptives (oral contraceptives, Depo Provera, implants, intrauterine devices, and periodic abstinence) during Round 15 (2011-2013) of the Rakai Community Cohort Survey (n=2206)...
March 4, 2018: Contraception
https://www.readbyqxmd.com/read/29482081/benign-osseous-metaplasia-of-the-breast-case-report
#14
Hassan Alyami, Emad Al-Osail, Shawgi Harbi, Mohammed Bu Bshait
INTRODUCTION: Benign Osseous metaplasia of the breast is rare, with only a few cases reported in the literature. Here we present a case of benign osseous metaplasia of the breast presenting as a breast lump. CASE PRESENTATION: 38-year-old previously well woman presented with a one-year history of bilateral breast pain and a left-sided breast lump. Ultrasound and mammography suggested calcified fibroadenoma. An ultrasound-guided true cut biopsy revealed fibrous tissue containing foci of adenosis in the presence of a myoepithelial cell layer...
2018: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29466918/multiple-sclerosis-and-hiv-a-case-of-multiple-sclerosis-immune-reconstitution-inflammatory-syndrome-associated-with-antiretroviral-therapy-initiation
#15
Pria Anand, Deanna Saylor
Studies have suggested that the incidence of multiple sclerosis (MS) in HIV-infected (HIV+) patients is lower than that of the general population. Here, we present a case of MS in an HIV+ patient with a relatively suppressed CD4 cell count who developed clinical and radiographic disease worsening in the setting of antiretroviral therapy (ART) initiation. A 47-year-old HIV+ woman (CD4 cell count 216 cells/µl) presented with decreased vision in her right eye. Magnetic resonance imaging (MRI) revealed optic nerve enhancement and open ring-enhancing lesions in the brain concerning for demyelinating disease...
January 1, 2018: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/29454382/high-risk-human-papillomavirus-prevalence-and-genotype-distribution-among-women-infected-with-hiv-in-manaus-amazonas
#16
Monique Figueiredo Teixeira, Meritxell Sabidó, André Luiz Leturiondo, Cynthia de Oliveira Ferreira, Kátia Luz Torres, Adele Schwartz Benzaken
BACKGROUND: Human immunodeficiency virus (HIV)-positive women have a high prevalence of human papillomavirus (HPV), and are infected with a broader range of HPV types than HIV-negative women. We aimed to determine the prevalence of cervical cytologic abnormalities, high-risk (HR)-HPV prevalence, type distribution according to the severity of cervical lesions and CD4 cell count and identify factors associated with HR-HPV infection among women living with HIV in Manaus, Amazonas. METHODS: We enrolled 325 women living with HIV that attended an infectious diseases referral hospital...
February 17, 2018: Virology Journal
https://www.readbyqxmd.com/read/29438439/mother-to-child-transmission-of-hiv-in-brazil-data-from-the-birth-in-brazil-study-a-national-hospital-based-study
#17
Rosa Maria Soares Madeira Domingues, Valeria Saraceni, Maria do Carmo Leal
AIMS: to estimate the mother to child transmission (MTCT) of HIV among infected pregnant women identified in the "Birth in Brazil" study and to evaluate care practices provided in order to identify missed opportunities at preventing the MTCT of HIV infection in the country. METHODS: Descriptive study using data obtained from the consultation of different databases: the "Birth in Brazil" study database and the Brazilian National Information Systems (NIS) databases...
2018: PloS One
https://www.readbyqxmd.com/read/29424772/systematic-identification-of-correlates-of-hiv-infection-an-x-wide-association-study
#18
Chirag J Patel, Jay Bhattacharya, John P A Ioannidis, Eran Bendavid
OBJECTIVE: Better identification of at-risk groups could benefit HIV-1 care programmes. We systematically identified HIV-1 risk factors in two nationally representative cohorts of women in the Demographic and Health Surveys. METHODS: We identified and replicated the association of 1415 social, economic, environmental, and behavioral factors with HIV-1 status. We used the 2007 and 2013-2014 surveys conducted among 5715 and 15 433 Zambian women, respectively (688 shared factors)...
April 24, 2018: AIDS
https://www.readbyqxmd.com/read/29394463/primary-orbital-melanoma-treated-with-orbital-exenteration-and-postoperative-radiotherapy-a-case-report-and-review-of-the-literature
#19
Christopher P Haskins, Sommer Nurkic, Kristianna M Fredenburg, Peter T Dziegielewski, William M Mendenhall
BACKGROUND: We report on a patient with human immunodeficiency virus (HIV)-positive disease with a primary orbital melanoma treated with surgery and adjuvant radiation. METHODS: A 53-year-old woman with HIV-positive disease presented with left-sided progressive ipsilateral vision loss and proptosis. An MRI scan revealed a mass-enhancing lesion measuring 2.1 × 2.6 × 2.5 cm abutting the optic nerve. The patient underwent left orbital exenteration with temporalis flap reconstruction, pathology revealing malignant melanoma, stage T1N0M0...
March 2018: Head & Neck
https://www.readbyqxmd.com/read/29390523/efficacy-of-eculizumab-in-an-adult-patient-with-hiv-associated-hemolytic-uremic-syndrome-a-case-report
#20
Marine Freist, Cyril Garrouste, Nora Szlavik, Paul Coppo, Alexandre Lautrette, Anne Elisabeth Heng
INTRODUCTION: Hemolytic uremic syndrome (HUS) in Human Immunodeficiency Virus (HIV)-positive patients has become a rare cause of kidney injury since the era of highly active antiretroviral therapy (HAART). Plasma exchange and antiretroviral therapy were previously recommended but often failed to achieve remission. We report a case of HUS in a HIV-positive patient treated successfully with eculizumab. CASE SUMMARY: A 52-year-old woman presented to hospital with acute renal failure, thrombocytopenia, anemia, and hypoxemia...
December 2017: Medicine (Baltimore)
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