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https://www.readbyqxmd.com/read/28923034/an-implementation-science-protocol-of-the-women-s-health-coop-in-healthcare-settings-in-cape-town-south-africa-a-stepped-wedge-design
#1
Wendee M Wechsberg, Jacqueline W Ndirangu, Ilene S Speizer, William A Zule, Winnifred Gumula, Courtney Peasant, Felicia A Browne, Laura Dunlap
BACKGROUND: HIV persists as a public health emergency in South Africa, especially among women of childbearing age. In response to the HIV epidemic, the Joint United Nations Programme on HIV/AIDS has put forth the 90-90-90 global goals to achieve an AIDS-free generation by 2020. This goal aspires to have 90% of people living with HIV diagnosed; 90% of those who test positive on sustained antiretroviral therapy (ART); and 90% of those on ART be virally suppressed. Ensuring access to ART is an important first step in reducing HIV incidence, especially among vulnerable populations such as women who use substances and bear the burden of HIV in South Africa...
September 18, 2017: BMC Women's Health
https://www.readbyqxmd.com/read/28882163/prevalence-and-significance-of-mycoplasma-genitalium-in-women-living-with-hiv-in-denmark
#2
Anne Marie Rosendahl Madsen, Kristina Thorsteinsson, Anne-Mette Lebech, Merete Storgaard, Terese L Katzenstein, Frederikke F Rönsholt, Isik Somuncu Johansen, Gitte Pedersen, Lars Noerregaard Nielsen, Aase Bengaard Andersen, Jørgen Skov Jensen
OBJECTIVE: Mycoplasma genitalium (M. genitalium) is a sexually transmitted pathogen associated with urethritis, cervicitis, and pelvic inflammatory disease. Previous studies have shown a strong association between M. genitalium and HIV infection, therefore screening and treatment for M. genitalium has been suggested as part of HIV prevention strategies. The objective of this study was to determine the prevalence of M. genitalium in women living with HIV (WLWH) in Denmark, and to compare the result with data on symptoms from the lower abdomen, sexual habits and immune status...
September 7, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28835824/acute-recurrent-lymphocytic-meningitis-in-an-immunocompetent-hiv-positive-african-woman-is-it-a-mollaret-s-meningitis-or-not
#3
Katie Tharshana Yoganathan, Soumeya Cherif, Mariam Rashid, Kathir Yoganathan
We report a case of acute recurrent meningitis in an HIV-positive immunocompetent woman. In this case, a 34-year-old African woman with a known HIV infection presented with symptoms of acute meningitis. She was on combination antiretroviral therapy with abacavir, lamivudine, and nevirapine. Her HIV RNA level was <70 IU/mL, and CD4 counts were 640 cells/mm(3). This indicates that she was not immunocompromised. She was febrile on examination, with marked neck stiffness. Her cerebrospinal fluid revealed raised white cell counts with 100% lymphocytes and mildly raised protein...
2017: SAGE open medical case reports
https://www.readbyqxmd.com/read/28831309/effect-of-efavirenz-on-endogenous-progesterone-concentrations-and-contraceptive-outcomes-among-ugandan-hiv-infected-women-coadministering-ethinylestradiol-levonorgestrel
#4
Grant Munkwase, Kuteesa R Bisaso, Othman Kakaire, Sarah Nanzigu
This study assessed the effect of efavirenz mid-dose plasma concentrations on mid-luteal endogenous progesterone concentrations and contraceptive outcomes among 49 HIV infected women coadministering ethinylestradiol/levonorgestrel, including 34 HIV positive women on Highly Active Antiretroviral Therapy (HAART) and 15 HAART naïve HIV infected women, purposively selected from Mulago Hospital, Uganda. A blood sample was collected once between days 20 and 22 of each woman's menstrual cycle for measuring endogenous progesterone and efavirenz concentrations by electrochemiluminescence technology and High Performance Liquid Chromatography (HPLC), respectively...
2017: AIDS Research and Treatment
https://www.readbyqxmd.com/read/28830394/young-women-s-perceptions-of-transactional-sex-and-sexual-agency-a-qualitative-study-in-the-context-of-rural-south-africa
#5
Meghna Ranganathan, Catherine MacPhail, Audrey Pettifor, Kathleen Kahn, Nomhle Khoza, Rhian Twine, Charlotte Watts, Lori Heise
BACKGROUND: Evidence shows that HIV prevalence among young women in sub-Saharan Africa increases almost five-fold between ages 15 and 24, with almost a quarter of young women infected by their early-to mid-20s. Transactional sex or material exchange for sex is a relationship dynamic that has been shown to have an association with HIV infection. METHODS: Using five focus group discussions and 19 in-depth interviews with young women enrolled in the HPTN 068 conditional cash transfer trial (2011-2015), this qualitative study explores young women's perceptions of transactional sex within the structural and cultural context of rural South Africa...
August 22, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28819499/multiple-jejunal-perforation-secondary-to-intestinal-tuberculosis-infection-a-case-report
#6
Anthony Lyonga Ngonge, Domin Sone Majunda Ekaney, Carlson-Babila Sama, Joffi Musonge-Effoe, Valery Sammah Effoe, Gerald Ekwen
Abdominal tuberculosis (TB) may affect any part of the gastrointestinal tract resulting in significant morbidity and mortality. There is an increase in the incidence of abdominal TB favored by the emergence of multi-drug resistant Mycobacterium tuberculosis and immunosuppression especially from HIV co-infection. Our case is that of a 31 year old HIV-positive woman, adherent to antiretroviral therapy, who presented with a 2 month history of progressive abdominal distention, drenching night sweat and fatigue, but without fever...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28797181/hiv-resistance-with-correlation-to-pmtct-regimen-in-hiv-infected-infants-in-northern-tanzania
#7
Dorothy Elizabeth Dow, Werner Schimana, Balthazar M Nyombi, Blandina T Mmbaga, Aisa M Shayo, John A Bartlett, Charles G Massambu, Emmanuel G Kifaro, Elizabeth L Turner, Todd DeMarco, Fangping Cai, Coleen Cunningham, Ann M Buchanan
Prevention of mother-to-child transmission (PMTCT) guidelines recommend that all HIV-infected pregnant woman receive antiretroviral therapy (Option B) and HIV-infected infants should initiate therapy with a protease inhibitor based regimen; however, implementation of these guidelines has lagged in many resource-limited settings. Tanzania only recently implemented these guidelines with little country specific data to inform whether HIV non-nucleoside reverse transcriptase inhibitor (NNRTI) resistance was present among infected infants under the Option A guidelines...
August 11, 2017: AIDS Research and Human Retroviruses
https://www.readbyqxmd.com/read/28760009/hiv-positive-pregnant-women-attending-the-prevention-of-mother-to-child-transmission-of-hiv-aids-pmtct-services-in-ethiopia-economic-productivity-losses-across-urban-rural-settings
#8
Elias Asfaw Zegeye, Josue Mbonigaba, Sylvia Blanche Kaye
HIV/AIDS impacts significantly on pregnant women and on children in Ethiopia. This impact has a multiplier effect on household economies and on productivity losses, and is expected to vary across rural and urban settings. Applying the human capital approach to data collected from 131 respondents, this study estimated productivity losses per HIV-positive pregnant woman-infant pair across urban and rural health facilities in Ethiopia, which in turn were used to estimate the national productivity loss. The study found that the annual productivity loss per woman-infant pair was Ethiopian birr (ETB) 7,433 or United States dollar (US$) 378 and ETB 625 (US$ 32) in urban and rural settings, respectively...
July 31, 2017: Psychology, Health & Medicine
https://www.readbyqxmd.com/read/28752487/the-demography-of-mental-health-among-mature-adults-in-a-low-income-high-hiv-prevalence-context
#9
Iliana V Kohler, Collin F Payne, Chiwoza Bandawe, Hans-Peter Kohler
Very few studies have investigated mental health in sub-Saharan Africa (SSA). Using data from Malawi, this article provides a first picture of the demography of depression and anxiety (DA) among mature adults (aged 45 or older) in a low-income country with high HIV prevalence. DA are more frequent among women than men, and individuals affected by one are often affected by the other. DA are associated with adverse outcomes, such as poorer nutrition intake and reduced work efforts. DA also increase substantially with age, and mature adults can expect to spend a substantial fraction of their remaining lifetime-for instance, 52 % for a 55-year-old woman-affected by DA...
August 2017: Demography
https://www.readbyqxmd.com/read/28741042/the-first-case-of-lymphogranuloma-venereum-in-a-woman-in-east-central-europe-and-its-multiple-co-infections
#10
Katerina Juzlova, Filip Rob, Hana Zakoucka, Andrea Kubatova, Zuzana Secnikova, Martina Krasova, Petr Bohac, Jana Hercogova
We are reporting the first case of lymphogranuloma venereum in women in East-Central Europe. A 22-year-old heterosexual woman attended our department of venereology. She complained about a burning sensation in the urethra and vaginal discharge. Many tests were performed, and lymphogranuloma venereum, syphilis, gonorrhea, chlamydial urethritis and cervicitis, genital herpes, genital warts, and hepatitis C were diagnosed. Lymphogranuloma venereum was originally endemic in tropical and subtropical areas, but since 2003, outbreaks of this infection have been reported in North America, Europe, and Australia in men who have sex with men (MSM) community...
July 24, 2017: Folia Microbiologica
https://www.readbyqxmd.com/read/28728348/effect-of-antiretroviral-therapy-art-on-change-in-fertility-intentions-of-hiv-positive-women-in-addis-ababa-ethiopia-a-prospective-follow-up-study
#11
Hussen Mekonnen
Objectives: The study aimed to assess change in fertility intentions 12 months after ART initiation among HIV positive women in Addis Ababa, Ethiopia. Methods: Institution based follow up study was conducted, among 360 HIV positive women in Addis Ababa; from June 2012 to October 2013. Logistic regression model was used to assess the influence socio-demographic, reproductive health and clinical characteristics on the change in fertility intention of women. Results: Overall, 41...
July 16, 2017: Epidemiology and Health
https://www.readbyqxmd.com/read/28726042/reproductive-desires-and-considerations-of-hiv-positive-men-in-heterosexual-relationships-in-new-york-city
#12
Karolynn Siegel, Étienne Meunier, Jack Ume Tocco, Helen-Maria Lekas
The reproductive desires of HIV-positive men have been investigated far less than those of HIV-positive women, especially in the US. This qualitative study of a sample of 94 HIV-positive men in New York City who were in a relationship with a woman of reproductive age examined their reasons for wanting a child as well as the conditions under which they would feel ready to attempt conception. Participants felt a child would make them feel normal, give meaning to their lives, or make others in their life happy...
July 19, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/28718492/-hiv-and-syphilis-coinfection-in-pregnancy-and-vertical-hiv-transmission-a-study-based-on-epidemiological-surveillance-data
#13
Lisiane M W Acosta, Tonantzin Ribeiro Gonçalves, Nêmora Tregnago Barcellos
Objective: To estimate the rate of HIV and syphilis coinfection among pregnant women living in Porto Alegre, Brazil, as well as the association of coinfection with vertical HIV transmission and socioeconomic variables. Method: This analytical retrospective cross-sectional study employed data from the regular epidemiological surveillance system for the period from 2010 to 2013. Data were obtained regarding pregnant women with HIV and exposed children, syphilis in pregnancy, and congenital syphilis...
December 2016: Revista Panamericana de Salud Pública, Pan American Journal of Public Health
https://www.readbyqxmd.com/read/28703726/motherhood-and-risk-for-human-immunodeficiency-virus-sexually-transmitted-infections-among-female-sex-workers-in-the-mexico-us-border-region
#14
Argentina E Servin, Elizabeth Reed, Kimberly C Brouwer, Carlos Magis-Rodriguez, Sabrina Boyce, Steffanie A Strathdee, Jay G Silverman
BACKGROUND: Globally, female sex workers (FSWs) have been identified as a high-risk group for human immunodeficiency virus (HIV) and sexually transmitted infections (STIs). However, as women of reproductive age, FSWs also have children. Few studies have investigated if financial responsibilities associated with motherhood increase women's vulnerability to HIV and STIs among FSWs. METHODS: From March 2013 to March 2014, 603 FSWs aged ≥18 years were recruited from Tijuana and Ciudad Juarez (Mexico) to participate in a study assessing HIV/STI risk environments...
August 2017: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/28692210/agency-as-a-mediator-in-the-pathway-from-transactional-sex-to-hiv-among-pregnant-women-in-swaziland-a-multigroup-path-analysis
#15
Rebecca Fielding-Miller, Kristin L Dunkle, Craig Hadley, Hannah Lf Cooper, Michael Windle
INTRODUCTION: Transactional sex is a structural driver of HIV for women and girls in sub-Saharan Africa. In transactional relationships, sexual and economic obligations intertwine and may have positive and negative effects on women's financial standing and social status. We conducted a clinic-based survey with pregnant women in Swaziland using a locally validated transactional sex scale to measure the association between subjective social status, transactional sex, and HIV status, and to assess whether this association differed according to a woman's agency within her relationship...
July 7, 2017: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/28679994/multicentric-castleman-s-disease-with-multiple-hepatic-mass-lesions-mimicking-malignant-liver-tumors
#16
Toshimitsu Ueki, Masaru Nasuno, Hiroko Kaiume, Yuki Hiroshima, Masahiko Sumi, Masahide Watanabe, Dai Inoue, Yasufumi Masaki, Yasuharu Sato, Masaru Kojima, Hikaru Kobayashi
Multicentric Castleman's disease (MCD) is a rare, non-malignant lymphoproliferative disorder. We report a case of MCD with multiple liver masses. A 26-year-old woman presented with asymptomatic anemia and hypoalbuminemia. Laboratory tests detected high CRP levels and findings indicative of polyclonal gammopathy. Abdominal CT revealed multiple hepatic large masses (≤10 cm) and partial calcification in the right lobe. Multiple enlarged lymph nodes were also identified in the cardiophrenic angle and porta hepatis...
2017: [Rinshō Ketsueki] the Japanese Journal of Clinical Hematology
https://www.readbyqxmd.com/read/28679418/transitioning-from-antenatal-surveillance-surveys-to-routine-hiv-testing-a-turning-point-in-the-mother-to-child-transmission-prevention-programme-for-hiv-surveillance-in-brazil
#17
Gerson Fernando Mendes Pereira, Meritxell Sabidó, Alessandro Caruso, Adele Schwartz Benzaken
BACKGROUND: In Brazil, due to the rapid increase in programmes for the prevention of mother-to-child transmission (PMTCT), routine programme data are widely available. The objective of this study was to assess the utility of programmatic data to replace HIV surveillance based on the antenatal care (ANC) surveillance survey (SS). METHODS: We analysed ANC SS data from 219 maternity service clinics. PMTCT variables were extracted from the ANC SS data collection form, which allowed us to capture and compare the ANC SS data and PMTCT HIV test results for each pregnant woman who completed the ANC SS...
July 5, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28662036/prevention-of-mother-to-child-transmission-of-hiv-postpartum-adherence-to-option-b-until-18-months-in-western-uganda
#18
Sarah Decker, Eva Rempis, Alexandra Schnack, Vera Braun, John Rubaihayo, Priscilla Busingye, Nazarius Mbona Tumwesigye, Gundel Harms, Stefanie Theuring
Since 2012, the WHO recommends Option B+ for the prevention of mother-to-child transmission of HIV. This approach entails the initiation of lifelong antiretroviral therapy in all HIV-positive pregnant women, also implying protection during breastfeeding for 12 months or longer. Research on long-term adherence to Option B+ throughout breastfeeding is scarce to date. Therefore, we conducted a prospective observational cohort study in Fort Portal, Western Uganda, to assess adherence to Option B+ until 18 months postpartum...
2017: PloS One
https://www.readbyqxmd.com/read/28623951/progressive-respiratory-distress-in-a-42-year-old-hiv-positive-woman-with-systemic-lupus-erythematosus
#19
Katongo Mutengo, Patrice Mukomena, Nason Lambwe, Owen Ngalamika
BACKGROUND: Identifying and treating the cause of pulmonary symptoms in HIV patients with underlying systemic lupus erythematosus (SLE) can be very challenging. Delays in diagnosing active SLE in HIV patients can lead to significant morbidity and even mortality. We report the case of an HIV-positive woman with SLE who presented with severe respiratory distress. CASE PRESENTATION: A 42-year-old HIV-positive woman presented with a 7-month history of anorexia, progressive dyspnoea, and a productive cough...
June 17, 2017: European Journal of Medical Research
https://www.readbyqxmd.com/read/28604240/the-influence-of-social-constructs-of-hegemonic-masculinity-and-sexual-behaviour-on-acceptability-of-vaginal-microbicides-in-zambia
#20
Oliver Mweemba, Rachael Dixey, Virginia Bond, Alan White
Vaginal microbicides are heralded as a woman's HIV prevention method. This study, conducted in a microbicide clinical trial setting in Zambia, explored how the social construction of masculinity and sexual behaviour influenced the acceptability of vaginal microbicides. The data were generated from 18 In-depth Interviews and 8 Focus Group Discussions. The data were analysed thematically. The study found that hegemonic masculinity influenced the use of vaginal microbicides positively and negatively, in multiple ways including: decision to initiate gel use, autonomous use of the gel, and consistent use of the gel...
June 12, 2017: Global Public Health
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