Atiene S Sagay, Szu-Chia Hsieh, Yu-Ching Dai, Charlotte Ajeong Chang, Jerry Ogwuche, Olukemi O Ige, Makshwar L Kahansim, Beth Chaplin, Godwin Imade, Michael Elujoba, Michael Paul, Donald J Hamel, Hideki Furuya, Ricardo Khoury, Viviane Sampaio Boaventura, Laíse de Moraes, Phyllis J Kanki, Wei-Kung Wang
OBJECTIVE: Chikungunya virus (CHIKV), a reemerging global public health concern, causes acute febrile illness, rash, and arthralgia and during pregnancy may affect both mothers and infants. Mother-to-child transmission (MTCT) of CHIKV in Africa remains understudied. METHODS: Our cohort study screened 1006 pregnant women with a Zika/dengue/CHIKV rapid test at two clinics in Nigeria between 2019 and 2022. Women who were rapid test positive were followed through pregnancy and their infants observed for six months, with a subset tested by RT-PCR and neutralization, to investigate seropositivity rates and MTCT of CHIKV...
December 4, 2023: International Journal of Infectious Diseases: IJID