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https://www.readbyqxmd.com/read/27922853/heart-sink-topics-in-sexually-transmitted-infections-vaccinations-anal-cancer-screening-and-overlapping-infection-epidemics-in-eastern-europe
#1
Karen E Rogstad
No abstract text is available yet for this article.
December 2, 2016: Current Opinion in Infectious Diseases
https://www.readbyqxmd.com/read/27921036/acute-kidney-injury-in-asia
#2
REVIEW
Li Yang
BACKGROUND: Acute kidney injury (AKI) is a common disorder and is associated with a high morbidity and mortality worldwide. The diversity of the climate and of the socioeconomic and developmental status in Asia has a great influence on the etiology and presentation of AKI in different regions. In view of the International Society of Nephrology's 0by25 initiative, more and more attention has been paid to AKI in Asian countries. SUMMARY: In this review, we summarize the recent achievements with regard to the prevalence and clinical patterns of AKI in Asian countries...
October 2016: Kidney Diseases
https://www.readbyqxmd.com/read/27918088/cerebrolysin-for-acute-ischaemic-stroke
#3
REVIEW
Liliya Eugenevna Ziganshina, Tatyana Abakumova, Ludivine Vernay
BACKGROUND: Cerebrolysin is a mixture of low-molecular-weight peptides and amino acids derived from pigs' brain tissue, which has potential neuroprotective and neurotrophic properties. It is widely used in the treatment of acute ischaemic stroke in Russia, Eastern Europe, China, and other Asian and post-Soviet countries. OBJECTIVES: To assess the benefits and risks of cerebrolysin for treating acute ischaemic stroke. SEARCH METHODS: In May 2016 we searched the Cochrane Stroke Group Trials Register, CENTRAL, MEDLINE, Embase, Web of Science Core Collection, with Science Citation Index, LILACS, OpenGrey, and a number of Russian Databases...
December 5, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27917361/il28b-genotype-is-associated-with-cirrhosis-or-transition-to-cirrhosis-in-treatment-naive-patients-with-chronic-hcv-genotype-1-infection-the-international-observational-gen-c-study
#4
Alessandra Mangia, Victor De Ledinghen, François Bailly, Javier Brahm, Jazeps Keiss, Jonas Valantinas, Nele Rasmann, Diethelm Messinger, Fernando Tatsch, Georgios Bakalos, Graham R Foster
BACKGROUND AND PURPOSE: Contradictory data exist on the association between host interleukin-28B (IL28B) rs12979860 genotype and liver fibrosis in patients with chronic hepatitis C (CHC). This large, international, observational study (NCT01675427/MV25600) investigated relationships between IL28B rs12979860 genotype and liver fibrosis stage in CHC patients. METHODS: A total of 3003 adult, treatment-naive CHC patients were enrolled into the study. Patients made one study visit to provide a blood sample for genotyping; other data were obtained from medical records...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27913025/mapping-monthly-rainfall-erosivity-in-europe
#5
Cristiano Ballabio, Pasquale Borrelli, Jonathan Spinoni, Katrin Meusburger, Silas Michaelides, Santiago Beguería, Andreas Klik, Sašo Petan, Miloslav Janeček, Preben Olsen, Juha Aalto, Mónika Lakatos, Anna Rymszewicz, Alexandru Dumitrescu, Melita Perčec Tadić, Nazzareno Diodato, Julia Kostalova, Svetla Rousseva, Kazimierz Banasik, Christine Alewell, Panos Panagos
Rainfall erosivity as a dynamic factor of soil loss by water erosion is modelled intra-annually for the first time at European scale. The development of Rainfall Erosivity Database at European Scale (REDES) and its 2015 update with the extension to monthly component allowed to develop monthly and seasonal R-factor maps and assess rainfall erosivity both spatially and temporally. During winter months, significant rainfall erosivity is present only in part of the Mediterranean countries. A sudden increase of erosivity occurs in major part of European Union (except Mediterranean basin, western part of Britain and Ireland) in May and the highest values are registered during summer months...
November 29, 2016: Science of the Total Environment
https://www.readbyqxmd.com/read/27912786/circulation-of-dirofilaria-repens-and-dirofilaria-immitis-in-moldova
#6
Tatiana Șuleșco, Heidrun von Thien, Lidia Toderaș, Ion Toderaș, Renke Lühken, Egbert Tannich
BACKGROUND: Over the last two decades, a significant spread of dirofilariasis has been observed in eastern and central Europe. However, data on the circulation of Dirofilaria spp. in Moldova were absent although direct neighbor states reported high incidence rates of human dirofilariasis. METHODS: Daily mean temperature data were used to calculate Dirofilaria spp. development units, which were used to estimate the potential for complete extrinsic development in the mosquitoes (= sum of potential Dirofilaria spp...
December 3, 2016: Parasites & Vectors
https://www.readbyqxmd.com/read/27907032/genetic-structure-in-the-northern-range-margins-of-common-ash-fraxinus-excelsior-l
#7
Mari Mette Tollefsrud, Tor Myking, Jørn Henrik Sønstebø, Vaidotas Lygis, Ari Mikko Hietala, Myriam Heuertz
During post glacial colonization, loss of genetic diversity due to leading edge effects may be attenuated in forest trees because of their prolonged juvenile phase, allowing many migrants to reach the colonizing front before populations become reproductive. The northern range margins of temperate tree taxa in Europe are particularly suitable to study the genetic processes that follow colonization because they have been little affected by northern refugia. Here we examined how post glacial range dynamics have shaped the genetic structure of common ash (Fraxinus excelsior L...
2016: PloS One
https://www.readbyqxmd.com/read/27906999/identification-geochemical-characterisation-and-significance-of-bitumen-among-the-grave-goods-of-the-7th-century-mound-1-ship-burial-at-sutton-hoo-suffolk-uk
#8
Pauline Burger, Rebecca J Stacey, Stephen A Bowden, Marei Hacke, John Parnell
The 7th century ship-burial at Sutton Hoo is famous for the spectacular treasure discovered when it was first excavated in 1939. The finds include gold and garnet jewellery, silverware, coins and ceremonial armour of broad geographical provenance which make a vital contribution to understanding the political landscape of early medieval Northern Europe. Fragments of black organic material found scattered within the burial were originally identified as 'Stockholm Tar' and linked to waterproofing and maintenance of the ship...
2016: PloS One
https://www.readbyqxmd.com/read/27905969/disparities-in-length-of-life-across-developed-countries-measuring-and-decomposing-changes-over-time-within-and-between-country-groups
#9
Sergey Timonin, Vladimir M Shkolnikov, Domantas Jasilionis, Pavel Grigoriev, Dmitry A Jdanov, David A Leon
BACKGROUND: Over the past half century the global tendency for improvements in longevity has been uneven across countries. This has resulted in widening of inter-country disparities in life expectancy. Moreover, the pattern of divergence appears to be driven in part by processes at the level of country groupings defined in geopolitical terms. A systematic quantitative analysis of this phenomenon has not been possible using demographic decomposition approaches as these have not been suitably adapted for this purpose...
August 11, 2016: Population Health Metrics
https://www.readbyqxmd.com/read/27905948/changes-in-life-expectancy-1950-2010-contributions-from-age-and-disease-specific-mortality-in-selected-countries
#10
Jochen Klenk, Ulrich Keil, Andrea Jaensch, Marcus C Christiansen, Gabriele Nagel
BACKGROUND: Changes of life expectancy over time serve as an interesting public health indicator for medical, social and economic developments within populations. The aim of this study was to quantify changes of life expectancy between 1950 and 2010 and relate these to main causes of death. METHODS: Pollard's actuarial method of decomposing life expectancy was applied to compare the contributions of different age- and disease-groups on life expectancy in 5-year intervals...
May 23, 2016: Population Health Metrics
https://www.readbyqxmd.com/read/27905902/understanding-the-value-of-social-networks-in-life-satisfaction-of-elderly-people-a-comparative-study-of-16-european-countries-using-share-data
#11
Florian Tomini, Sonila M Tomini, Wim Groot
BACKGROUND: Networks of family and friends are a source of support and are generally associated with higher life satisfaction values among older adults. On the other hand, older adults who are satisfied with their life may be more able to develop and maintain a wider social network. For this reason, the causal link between size and composition of the social networks and satisfaction with life is yet to be explored. This paper investigates the effect of the 'size', (number of family and friends, and network) and the 'composition' (the proportion of friends over total number of persons) of the social network on life satisfaction among older adults (50+)...
December 1, 2016: BMC Geriatrics
https://www.readbyqxmd.com/read/27903602/whole-genome-sequencing-of-mycobacterium-tuberculosis-provides-insight-into-the-evolution-and-genetic-composition-of-drug-resistant-tuberculosis-in-belarus
#12
Kurt R Wollenberg, Christopher A Desjardins, Aksana Zalutskaya, Vervara Slodovnikova, Andrew J Oler, Mariam Quiñones, Thomas Abeel, Sinead B Chapman, Michael Tartakovsky, Andrei Gabrielian, Sven Hoffner, Aliaksandr Skrahin, Bruce W Birren, Alexander Rosenthal, Alena Skrahina, Ashlee M Earl
The emergence and spread of drug resistant Mycobacterium tuberculosis (DR-TB) is a critical global health issue. Eastern Europe has some of the highest incidences of DR-TB, particularly multidrug-resistant (MDR) and extensively drug-resistant (XDR) TB. To better understand the genetic composition and evolution of MDR- and XDR-TB in the region, we sequenced and analyzed the genomes of 138 M. tuberculosis isolates from 97 patients sampled between 2010 and 2013 in Minsk, Belarus. MDR and XDR-TB isolates were significantly more likely to belong to the Beijing lineage than to the Euro-American lineage, and known resistance-conferring loci accounted for the majority of phenotypic resistance to first- and second-line drugs in MDR and XDR-TB...
November 30, 2016: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/27901622/childhood-asthma-in-batumi-georgia-prevalence-correlates-potential-underdiagnosis
#13
Vakhtang Beridze, Lia Abuladze, Naira Partenadze, Tamar Bakhtadze, Joshua Lawson, Jan E Zejda
OBJECTIVE: A relative lack of data for Eastern Europe and unknown epidemiology of childhood asthma in Batumi (Georgia) justified a study aimed at determining the prevalence of physician-diagnosed asthma and related respiratory conditions, a comparison of the prevalence of these conditions between urban and rural children, and identification of their environmental correlates. METHODS: Subjects of the cross-sectional population-based study were 3238 urban and 2081 rural children aged 5-17 years whose respiratory status was assessed using the ISAAC questionnaire...
November 30, 2016: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/27899125/preventive-measures-aimed-at-minimizing-the-risk-of-african-swine-fever-virus-spread-in-pig-farming-systems
#14
REVIEW
Silvia Bellini, Domenico Rutili, Vittorio Guberti
African swine fever (ASF) is one of the most severe diseases of pigs; it has a drastic impact on the pig industry, causing serious socio-economic consequences to pig farmers and pork producers. In Europe, there are currently two main clusters of infection; one in Sardinia caused by strains of African swine fever virus (ASFV) belonging to genotype I and another in Eastern Europe caused by strains of ASFV belonging to genotype II. The latter is inducing an acute form of ASF and it represents a serious threat to the pig sector...
November 29, 2016: Acta Veterinaria Scandinavica
https://www.readbyqxmd.com/read/27893861/attitudes-towards-intimate-partner-violence-against-women-among-women-and-men-in-39-low-and-middle-income-countries
#15
Thach Duc Tran, Hau Nguyen, Jane Fisher
BACKGROUND: Violence against women perpetrated by an intimate partner (IPV) is prevalent in low- and middle-income countries (LAMIC). The aim was to describe the attitudes of women and men towards perpetration of physical violence to women by an intimate partner, in a large group of low- and middle-income countries. METHODS AND FINDINGS: We used data from Round Four of the UNICEF Multiple Indicator Cluster Surveys. Attitudes towards IPV against women were assessed by a study-specific scale asking if 'wife beating' is justified in any of five circumstances...
2016: PloS One
https://www.readbyqxmd.com/read/27890073/switching-to-nilotinib-versus-imatinib-dose-escalation-in-patients-with-chronic-myeloid-leukaemia-in-chronic-phase-with-suboptimal-response-to-imatinib-lasor-a-randomised-open-label-trial
#16
Jorge E Cortes, Carmino Antonio De Souza, Manuel Ayala, Jose Luis Lopez, Eduardo Bullorsky, Sandip Shah, Xiaojun Huang, K Govind Babu, Kudrat Abdulkadyrov, José Salvador Rodrigues de Oliveira, Zhi-Xiang Shen, Tomasz Sacha, Israel Bendit, Zhizhou Liang, Tina Owugah, Tomasz Szczudlo, Sadhvi Khanna, Rafik Fellague-Chebra, Philipp D le Coutre
BACKGROUND: Optimal management of patients with chronic myeloid leukaemia in chronic phase with suboptimal cytogenetic response remains undetermined. This study aimed to investigate the safety and efficacy of switching to nilotinib vs imatinib dose escalation for patients with suboptimal cytogenetic response on imatinib. METHODS: We did a phase 3, open-label, randomised trial in patients with chronic myeloid leukaemia in chronic phase with suboptimal cytogenetic response to imatinib according to the 2009 European LeukemiaNet criteria, in Latin America, Europe, and Asia (59 hospitals and care centres in 12 countries)...
December 2016: Lancet Haematology
https://www.readbyqxmd.com/read/27889059/chad-genetic-diversity-reveals-an-african-history-marked-by-multiple-holocene-eurasian-migrations
#17
Marc Haber, Massimo Mezzavilla, Anders Bergström, Javier Prado-Martinez, Pille Hallast, Riyadh Saif-Ali, Molham Al-Habori, George Dedoussis, Eleftheria Zeggini, Jason Blue-Smith, R Spencer Wells, Yali Xue, Pierre A Zalloua, Chris Tyler-Smith
Understanding human genetic diversity in Africa is important for interpreting the evolution of all humans, yet vast regions in Africa, such as Chad, remain genetically poorly investigated. Here, we use genotype data from 480 samples from Chad, the Near East, and southern Europe, as well as whole-genome sequencing from 19 of them, to show that many populations today derive their genomes from ancient African-Eurasian admixtures. We found evidence of early Eurasian backflow to Africa in people speaking the unclassified isolate Laal language in southern Chad and estimate from linkage-disequilibrium decay that this occurred 4,750-7,200 years ago...
December 1, 2016: American Journal of Human Genetics
https://www.readbyqxmd.com/read/27888547/towards-a-whole-genome-sequence-for-rye-secale-cereale-l
#18
Eva Bauer, Thomas Schmutzer, Ivan Barilar, Martin Mascher, Heidrun Gundlach, Mihaela M Martis, Sven O Twardziok, Bernd Hackauf, Andres Gordillo, Peer Wilde, Malthe Schmidt, Viktor Korzun, Klaus F X Mayer, Karl Schmid, Chris-Carolin Schön, Uwe Scholz
We report on a whole-genome draft sequence of rye (Secale cereale L.). Rye is a diploid Triticeae species closely related to wheat and barley and an important crop for food and feed in Central and Eastern Europe. Through whole-genome shotgun (WGS) sequencing of the 7.9 Gbp genome of the winter rye inbred line Lo7 we obtained a de novo assembly represented by 1.29 million scaffolds covering a total length of 2.8 Gbp. Our reference sequence represents nearly the entire low-copy portion of the rye genome. This genome assembly was used to predict 27,784 rye gene models based on homology to sequenced grass genomes...
November 26, 2016: Plant Journal: for Cell and Molecular Biology
https://www.readbyqxmd.com/read/27884116/kidney-disease-in-the-elderly-biopsy-based-data-from-14-renal-centers-in-poland
#19
Agnieszka Perkowska-Ptasinska, Dominika Deborska-Materkowska, Artur Bartczak, Tomasz Stompor, Tomasz Liberek, Barbara Bullo-Piontecka, Anna Wasinska, Agnieszka Serwacka, Marian Klinger, Jolanta Chyl, Michal Kuriga, Robert Malecki, Krzysztof Marczewski, Bogdan Hryniewicz, Tadeusz Gregorczyk, Monika Wieliczko, Stanislaw Niemczyk, Olga Rostkowska, Leszek Paczek, Magdalena Durlik
BACKGROUND: Longer life expectancy is associated with an increasing prevalence of kidney disease. Aging itself may cause renal damage, but the spectrum of kidney disorders that affect elderly patients is diverse. Few studies, mostly form US, Asia and West Europe found differences in the prevalence of some types of kidney diseases between elderly and younger patients based on renal biopsy findings, with varied proportion between glomerulopathies and arterionephrosclerosis as a dominant injury found...
November 25, 2016: BMC Nephrology
https://www.readbyqxmd.com/read/27883944/allocative-and-implementation-efficiency-in-hiv-prevention-and-treatment-for-people-who-inject-drugs
#20
Clemens Benedikt, Sherrie L Kelly, David Wilson, David P Wilson
BACKGROUND: Estimated global new HIV infections among people who inject drugs (PWID) remained stable over the 2010-2015 period and the target of a 50% reduction over this period was missed. To achieve the 2020 UNAIDS target of reducing adult HIV infections by 75% compared to 2010, accelerated action in scaling up HIV programs for PWID is required. In a context of diminishing external support to HIV programs in countries where most HIV-affected PWID live, it is essential that available resources are allocated and used as efficiently as possible...
November 21, 2016: International Journal on Drug Policy
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