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https://www.readbyqxmd.com/read/28938142/insulin-regimens-and-glycemic-control-in-different-parts-of-europe-over-4years-after-starting-insulin-in-people-with-type-2-diabetes-data-from-the-credit-non-interventional-study
#1
Lawrence Blonde, Michel Marre, Maya Vincent, Sandrine Brette, Valerie Pilorget, Nicholas Danchin, Giacomo Vespasiani, Philip Home
AIMS: A number of insulin regimens are used in type 2 diabetes. This analysis aims to better understand the evolution of insulin therapy in different regions of Europe. METHODS: Data from people starting any insulin were collected in eastern Europe (EEur: Croatia, Russia, Ukraine), northern Europe (NEur: Finland, Germany, UK) and southern Europe (SEur: France, Italy, Portugal, Spain). Retrospective data on starting insulin and prospective follow-up data were extracted from clinical records...
August 31, 2017: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/28936408/emerging-trends-in-epidemiology-of-hepatitis-b-virus-infection
#2
REVIEW
Cristina Stasi, Caterina Silvestri, Fabio Voller
Although a vaccine against hepatitis B virus (HBV) has been available since 1982, the prevalence of adults with chronic HBV infection in sub-Saharan Africa and East Asia is still estimated at 5-10%. A high rate of chronic infections is also found in the Amazon and the southern parts of eastern and central Europe. In the Middle East and the Indian subcontinent, the prevalence is 2-5%. Less than 1% of the population of Western Europe and North America is chronically infected. Given the high prevalence of infections (such as hepatitis) among inmates, prison is considered a reservoir for facilitating such infections...
September 28, 2017: Journal of Clinical and Translational Hepatology
https://www.readbyqxmd.com/read/28936133/migrants-decision-process-shaping-work-destination-choice-the-case-of-long-term-care-work-in-the-united-kingdom-and-norway
#3
Karen Christensen, Shereen Hussein, Mohamed Ismail
Escalating demands for formal long-term care (LTC) result in the reliance on migrant workers in many developed countries. Within Europe, this is currently framed by progressive European immigration policies favouring inter-European mobility. Using the UK and Norway as case studies, this article has two main aims: (1) to document changes in the contribution of European Union (EU) migrants to the LTC sectors in Western Europe, and (2) to gain further understanding of migrants' decision-processes relating to destination and work choices...
September 2017: European Journal of Ageing
https://www.readbyqxmd.com/read/28935118/ex-vivo-trypanocidal-activity-of-1-2-hydroxybenzylidene-thiosemicarbazide-against-trypanosoma-equiperdum
#4
N Parra, M Jaume, K Boscán, A Hernández, A Mijares, M González, Y Alvarado, J Restrepo
Trypanosoma equiperdum is the causative agent of dourine, a venereal disease in horses and donkeys. This parasite has a widely distribution, is found in Africa, Asia, Southern and Eastern Europe, Russia, Mexico and Venezuela. The T. equiperdum is morphologically indistinguishable to other Trypanozoon species, however differs from other mammalian trypanosomes due to the fact that it is primarily a tissue parasite, generating cutaneous plaques, swelling of genitalia and neurological signs. The aim of this study was to evaluate the trypanocidal effectiveness of a set of derivatives of thiosemicarbazones on a T...
July 8, 2017: Veterinary Parasitology
https://www.readbyqxmd.com/read/28934957/phylogenetic-analyses-of-bat-associated-bugs-hemiptera-cimicidae-cimicinae-and-cacodminae-indicate-two-new-species-close-to-cimex-lectularius
#5
Sándor Hornok, Krisztina Szőke, Sándor A Boldogh, Attila D Sándor, Jenő Kontschán, Vuong Tan Tu, Ali Halajian, Nóra Takács, Tamás Görföl, Péter Estók
BACKGROUND: Bats are regarded as the primary (ancestral) hosts of bugs of the family Cimicidae. The historically and economically most important species in the family is the common bedbug (Cimex lectularius), because of its worldwide occurrence and association with humans. This molecular-phylogenetic study was initiated in order to expand the knowledge on the phylogeny of cimicid bugs of bats, by investigating samples from Hungary, Romania (representing central-eastern Europe) and two further countries (South Africa and Vietnam)...
September 21, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28934946/genome-wide-snp-data-unveils-the-globalization-of-domesticated-pigs
#6
Bin Yang, Leilei Cui, Miguel Perez-Enciso, Aleksei Traspov, Richard P M A Crooijmans, Natalia Zinovieva, Lawrence B Schook, Alan Archibald, Kesinee Gatphayak, Christophe Knorr, Alex Triantafyllidis, Panoraia Alexandri, Gono Semiadi, Olivier Hanotte, Deodália Dias, Peter Dovč, Pekka Uimari, Laura Iacolina, Massimo Scandura, Martien A M Groenen, Lusheng Huang, Hendrik-Jan Megens
BACKGROUND: Pigs were domesticated independently in Eastern and Western Eurasia early during the agricultural revolution, and have since been transported and traded across the globe. Here, we present a worldwide survey on 60K genome-wide single nucleotide polymorphism (SNP) data for 2093 pigs, including 1839 domestic pigs representing 122 local and commercial breeds, 215 wild boars, and 39 out-group suids, from Asia, Europe, America, Oceania and Africa. The aim of this study was to infer global patterns in pig domestication and diversity related to demography, migration, and selection...
September 21, 2017: Genetics, Selection, Evolution: GSE
https://www.readbyqxmd.com/read/28934332/end-member-modelling-as-a-tool-for-climate-reconstruction-an-eastern-mediterranean-case-study
#7
Sarah Beuscher, Stefan Krüger, Werner Ehrmann, Gerhard Schmiedl, Yvonne Milker, Helge Arz, Hartmut Schulz
The Eastern Mediterranean Sea is a sink for terrigenous sediments from North Africa, Europe and Asia Minor. Its sediments therefore provide valuable information on the climate dynamics in the source areas and the associated transport processes. We present a high-resolution dataset of sediment core M40/4_SL71, which was collected SW of Crete and spans the last ca. 180 kyr. We analysed the clay mineral composition, the grain size distribution within the silt fraction, and the abundance of major and trace elements...
2017: PloS One
https://www.readbyqxmd.com/read/28933005/human-papillomavirus-in-oropharyngeal-squamous-cell-carcinoma-in-south-eastern-norway-prevalence-genotype-and-survival
#8
Guro Haugen Fossum, Agnes Kathrine Lie, Peter Jebsen, Lars Erik Sandlie, Jon Mork
The objectives of this study were to assess the prevalence of high-risk human papillomavirus (HR HPV) and survival in all oropharyngeal cancer (OPSCC) patients in a Norwegian population cohort in 2010-2011. Clinical data were retrieved from hospital records. Biopsies from 166 patients were tested for the presence of HR HPV by qualitative polymerase chain reaction (qPCR). p16 immunohistochemistry was performed in 138 cases. Survival was compared between groups of patients with tumors positive for HPV16 and other HR HPV genotypes, and patients with HPV negative tumors...
September 20, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28931103/-current-situation-of-palliative-care-in-hungary-integrated-palliative-care-model-as-a-breakout-possibility
#9
Gábor Benyó, Miklós Lukács, Csilla Busa, László Mangel, Ágnes Csikós
Modern palliative-hospice care has gained space in Europe for more than 50 years. Since the initial empirical work of Cicely Saunders, palliative medicine has gained its place in evidence-based medicine in more and more countries. However, development, as in many other medical fields, is not uniform, there are big differences between countries in the world. There are also significant differences in development of care and the level of services within the European Union amongst Western and Eastern European countries...
September 20, 2017: Magyar Onkologia
https://www.readbyqxmd.com/read/28922908/vitamin-d-status-in-internationally-adopted-children-the-experience-in-northwest-italy
#10
Irene Raffaldi, Silvia Garazzino, Giuseppina Ballardini, Mauro Zaffaroni, Nicolino Grasso, Gianni Bona, Pier-Angelo Tovo, Andrea Guala
BACKGROUND: The majority of internationally adopted children, before adoption, might have experienced malnutrition, exposure to infectious diseases, environmental deprivation and neglect; they could also develop medical problems such as vitamin D deficiency. Scantly data are available about vitamin D status in internationally adopted children and, to our knowledge, no report exists on Italian adoptees. METHODS: We carried out a prospective multicenter study, involving three Pediatric Centers in Piedmont, Italy, in order to collect information about 25-hydroxyvitamin D [25(OH)D] profile in adoptees, shortly after their arrival in Italy...
September 15, 2017: Minerva Pediatrica
https://www.readbyqxmd.com/read/28921895/genetic-characterization-of-african-swine-fever-virus-isolates-from-soft-ticks-at-the-wildlife-domestic-interface-in-mozambique-and-identification-of-a-novel-genotype
#11
C J Quembo, F Jori, W Vosloo, L Heath
African swine fever virus (ASFV) is one of the most threatening infectious diseases of pigs. There are not sufficient data to indicate the importance of the sylvatic cycle in the spread and maintenance of the disease locally and potentially, globally. To assess the capacity to maintain ASF in the environment, we investigated the presence of soft tickreservoirs of ASFV in Gorongosa National Park (GNP) and its surrounding villages. A total of 1,658 soft ticks were recovered from warthog burrows and pig pens at the wildlife/livestock interface of the GNP and viral DNA was confirmed by nested PCR in 19% of Ornithodoros porcinus porcinus and 15% of O...
September 17, 2017: Transboundary and Emerging Diseases
https://www.readbyqxmd.com/read/28919116/global-regional-and-national-age-sex-specific-mortality-for-264-causes-of-death-1980-2016-a-systematic-analysis-for-the-global-burden-of-disease-study-2016
#12
(no author information available yet)
BACKGROUND: Monitoring levels and trends in premature mortality is crucial to understanding how societies can address prominent sources of early death. The Global Burden of Disease 2016 Study (GBD 2016) provides a comprehensive assessment of cause-specific mortality for 264 causes in 195 locations from 1980 to 2016. This assessment includes evaluation of the expected epidemiological transition with changes in development and where local patterns deviate from these trends. METHODS: We estimated cause-specific deaths and years of life lost (YLLs) by age, sex, geography, and year...
September 16, 2017: Lancet
https://www.readbyqxmd.com/read/28915462/abundance-of-large-old-trees-in-wood-pastures-of-transylvania-romania
#13
Tibor Hartel, Jan Hanspach, Cosmin I Moga, Lucian Holban, Árpád Szapanyos, Réka Tamás, Csaba Hováth, Kinga-Olga Réti
Wood-pastures are special types of agroforestry systems that integrate trees with livestock grazing. Wood pastures can be hotspots for large old tree abundance and have exceptional natural values; but they are declining all over Europe. While presence of large old trees in wood-pastures can provide arguments for their maintenance, actual data on their distribution and abundance are sparse. Our study is the first to survey large old trees in Eastern Europe over such a large area. We surveyed 97 wood-pastures in Transylvania (Romania) in order to (i) provide a descriptive overview of the large old tree abundance; and (ii) to explore the environmental determinants of the abundance and persistence of large old trees in wood-pastures...
September 12, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28914233/lessons-from-two-cases-of-radiation-induced-skin-injuries-in-fluoroscopic-procedures-in-bulgaria
#14
Desislava Kostova-Lefterova, Jenia Vassileva, M M Rehani
Radiation-induced injuries to patient skin as a result of fluoroscopy guided interventional procedures are infrequently reported, often misdiagnosed and there is a need to learn lessons from every injury. Methods: This paper describes two cases of radiation induced skin injuries that are, to the best of our knowledge, the first ever reported cases from Bulgaria and possibly from Eastern Europe, and would thus have educational value. Results: The important messages from the skin injuries reported here are: lack of awareness among part of the interventional specialists about the potential for radiation induced skin injury, misdiagnosis after injury happened because of lack of awareness and knowledge among general physicians, dermatologists and surgeons who followed up cases of skin injuries; lack of system to monitor patients with relatively high exposure; important role played by the medical physicist in diagnosing the injury and overall in initiating actions; role of training and informational material displayed in interventional facilities...
September 15, 2017: Journal of Radiological Protection: Official Journal of the Society for Radiological Protection
https://www.readbyqxmd.com/read/28905230/molecular-detection-of-anaplasma-platys-anaplasma-phagocytophilum-and-wolbachia-sp-but-not-ehrlichia-canis-in-croatian-dogs
#15
Doroteja Huber, Irena Reil, Sanja Duvnjak, Daria Jurković, Damir Lukačević, Miroslav Pilat, Ana Beck, Željko Mihaljević, Lea Vojta, Adam Polkinghorne, Relja Beck
The bacteria Anaplasma platys, Anaplasma phagocytophilum and Ehrlichia canis are tick-borne agents that cause canine vector-borne disease. The prevalence of these pathogens in South Eastern Europe is unknown with the exception of an isolated case of A. platys detected in a dog imported into Germany from Croatia. To gain a better insight into their presence and prevalence, PCR-based screening for these bacterial pathogens was performed on domesticated dogs from different regions of Croatia. Blood samples from 1080 apparently healthy dogs from coastal and continental parts of Croatia as well as tissue samples collected from 63 deceased dogs with a history of anaemia and thrombocytopenia were collected for molecular screening by an Anaplasmataceae-specific 16S rRNA conventional PCR...
September 14, 2017: Parasitology Research
https://www.readbyqxmd.com/read/28905167/molecular-diversity-and-phylogeny-of-indigenous-rhizobium-leguminosarum-strains-associated-with-trifolium-repens-plants-in-romania
#16
Rodica C Efrose, Craita M Rosu, Catalina Stedel, Andrei Stefan, Culita Sirbu, Lucian D Gorgan, Nikolaos E Labrou, Emmanouil Flemetakis
The symbiotic nitrogen fixing legumes play an essential role in sustainable agriculture. White clover (Trifolium repens L.) is one of the most valuable perennial legumes in pastures and meadows of temperate regions. Despite its great agriculture and economic importance, there is no detailed available information on phylogenetic assignation and characterization of rhizobia associated with native white clover plants in South-Eastern Europe. In the present work, the diversity of indigenous white clover rhizobia originating in 11 different natural ecosystems in North-Eastern Romania were assessed by a polyphasic approach...
September 13, 2017: Antonie Van Leeuwenhoek
https://www.readbyqxmd.com/read/28904263/concerning-increase-in-antimicrobial-resistance-in-shiga-toxin-producing-escherichia-coli-isolated-from-young-animals-during-1980-2016
#17
Flore Chirila, Alexandra Tabaran, Nicodim Fit, George Nadas, Marian Mihaiu, Flaviu Tabaran, Cornel Cătoi, Oana Lucia Reget, Sorin Daniel Dan
This study was conducted in order to assess the antimicrobial resistance patterns of E. coli isolated from young animals affected between 1980 and 2016. The selected isolates for this study (n=175) carried stx1/stx2 genes and the most prevalent type of pathogenic E. coli found belonged to serogroup O101, antigen (K99)-F41 positive. All STEC-positive isolates were tested for susceptibility to 11 antimicrobials. Multidrug resistance (MDR) increased from 11% during the 1980s to 40% between 2000 and 2016. Resistance to tetracycline and streptomycin was the most frequent co-resistance phenotype (37%)...
September 12, 2017: Microbes and Environments
https://www.readbyqxmd.com/read/28903779/hepatitis-delta-virological-and-clinical-aspects
#18
REVIEW
Luan Felipo Botelho-Souza, Mariana Pinheiro Alves Vasconcelos, Alcione de Oliveira Dos Santos, Juan Miguel Villalobos Salcedo, Deusilene Souza Vieira
There are an estimated 400 million chronic carriers of HBV worldwide; between 15 and 20 million have serological evidence of exposure to HDV. Traditionally, regions with high rates of endemicity are central and northern Africa, the Amazon Basin, eastern Europe and the Mediterranean, the Middle East and parts of Asia. There are two types of HDV/HBV infection which are differentiated by the previous status infection by HBV for the individual. Individuals with acute HBV infection contaminated by HDV is an HDV/HBV co-infection, while individuals with chronic HBV infection contaminated by HDV represent an HDV/HBV super-infection...
September 13, 2017: Virology Journal
https://www.readbyqxmd.com/read/28893637/advances-in-the-diagnosis-of-bovine-besnoitiosis-current-options-and-applications-for-control
#19
REVIEW
Daniel Gutiérrez-Expósito, Ignacio Ferre, Luis M Ortega-Mora, Gema Álvarez-García
Bovine besnoitiosis, which is caused by the tissue cyst-forming intracellular parasite Besnoitia besnoiti, is a chronic and debilitating disease that is responsible for severe economic losses in the cattle raised under extensive husbandry systems. The absence of vaccines, treatments or a health scheme at local, national and international levels has led to a rapid spread of bovine besnoitiosis from western Europe towards eastern countries and northwards. Moreover, this parasitic disease is widely present in many sub-Saharan countries...
September 9, 2017: International Journal for Parasitology
https://www.readbyqxmd.com/read/28887467/long-term-impact-of-amazon-river-runoff-on-northern-hemispheric-climate
#20
S Jahfer, P N Vinayachandran, Ravi S Nanjundiah
Amazon discharges a large volume of freshwater into the ocean, yet its impact on climate is largely unknown. Climate projections show that a warmer northern tropical Atlantic Ocean together with a warmer equatorial Pacific lead to extreme droughts in the Amazonia, considerably reducing the Amazon runoff. Here we present results from coupled model simulations and observations on the climatic response to a significant reduction in Amazon runoff into the Atlantic Ocean. Climate model simulation without Amazon runoff resulted in cooler equatorial Atlantic, weakening the Hadley cell and thereby the atmospheric meridional cells...
September 8, 2017: Scientific Reports
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