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https://www.readbyqxmd.com/read/28924454/detection-of-enterotoxigenic-bacteroides-fragilis-in-patients-with-ulcerative-colitis
#1
Samin Zamani, Sonia Hesam Shariati, Mohammad Reza Zali, Hamid Asadzadeh Aghdaei, Akram Sarabi Asiabar, Saied Bokaie, Bizhan Nomanpour, Leonardo Antonio Sechi, Mohammad Mehdi Feizabadi
PURPOSE: Ulcerative colitis (UC) as a type of inflammatory bowel disease (IBD), presumed to occur as a consequence of increased immune responses to intestinal microbiota in genetically susceptible individuals. Enterotoxigenic Bacteroides fragilis (ETBF) strains are important intestinal bacteria that can be involved in IBD. The aim of this study was to design a quantitative assay for detection of B. fragilis and ETBF and also to find their association with UC. METHODS: Ninety-five biopsies were collected from patients with UC (n = 35) and with no IBD (nIBD, n = 60)...
2017: Gut Pathogens
https://www.readbyqxmd.com/read/28863535/dilution-effects-on-combined-magnetic-and-electric-dipole-interactions-a-study-of-ferromagnetic-cobalt-nanoparticles-with-tuneable-interactions
#2
M Hod, A Dobroserdova, S Samin, C Dobbrow, A M Schmidt, M Gottlieb, S Kantorovich
Improved understanding of complex interactions between nanoparticles will facilitate the control over the ensuing self-assembled structures. In this work, we consider the dynamic changes occurring upon dilution in the self-assembly of a system of ferromagnetic cobalt nanoparticles that combine magnetic, electric, and steric interactions. The systems examined here vary in the strength of the magnetic dipole interactions and the amount of point charges per particle. Scattering techniques are employed for the characterization of the self-assembly aggregates, and zeta-potential measurements are employed for the estimation of surface charges...
August 28, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28837622/lef1-dependent-hypothalamic-neurogenesis-inhibits-anxiety
#3
Yuanyuan Xie, Dan Kaufmann, Matthew J Moulton, Samin Panahi, John A Gaynes, Harrison N Watters, Dingxi Zhou, Hai-Hui Xue, Camille M Fung, Edward M Levine, Anthea Letsou, K C Brennan, Richard I Dorsky
While innate behaviors are conserved throughout the animal kingdom, it is unknown whether common signaling pathways regulate the development of neuronal populations mediating these behaviors in diverse organisms. Here, we demonstrate that the Wnt/ß-catenin effector Lef1 is required for the differentiation of anxiolytic hypothalamic neurons in zebrafish and mice, although the identity of Lef1-dependent genes and neurons differ between these 2 species. We further show that zebrafish and Drosophila have common Lef1-dependent gene expression in their respective neuroendocrine organs, consistent with a conserved pathway that has diverged in the mouse...
August 2017: PLoS Biology
https://www.readbyqxmd.com/read/28797409/ivus-oct-and-coronary-artery%C3%A2-calcification-is-there-a-bone-of-contention
#4
EDITORIAL
Samin K Sharma, Yuliya Vengrenyuk, Annapoorna S Kini
No abstract text is available yet for this article.
August 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28795527/utility-of-the-guideliner-catheter-for-percutaneous-coronary-interventions-in-patients-with-prior-transcatheter-aortic-valve-replacement
#5
Aditya S Bharadwaj, Samit Bhatheja, Samin K Sharma, Annapoorna S Kini
The safety and utility of GuideLiner catheters in complex percutaneous coronary interventions (PCI) has been well established. Patients with prior trans-catheter aortic valve replacement especially with CoreValve, who present for PCI, pose a unique set of challenges. Not only does the operator often encounter difficulty with selective engagement of coronary ostia through the struts of the CoreValve, but also the complex nature of the underlying CAD in this high-risk population. We present a case series to illustrate the use of GuideLiner catheter as an adjunctive tool for PCI in this patient population...
August 10, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28777194/pancreatic-ductal-adenocarcinoma-with-high-radiotracer-uptake-in-68ga-prostate-specific-membrane-antigen-pet-ct
#6
Samine Sahbai, Petra Rieping, Christina Pfannenberg, Christian la Fougére, Matthias Reimold
Prostate-specific membrane antigen imaging with PET/CT is increasingly used in prostate cancer and was shown to have a high diagnostic performance. We report a clinical case of a 67-year-old man with previous history of operated prostate cancer and increasing prostate-specific antigen blood level. Ga-HBED-CC prostate-specific membrane antigen PET/CT imaging was indicated for the assessment of local recurrence and lymph node metastases of prostate cancer. In addition, a soft tissue mass in the body of the pancreas with high radiotracer uptake was detected...
September 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28774521/a-comparison-of-undergraduate-clinical-ophthalmology-learning-methods-smart-phone-television-display-versus-slit-lamp-teaching-telescope
#7
Sandy Zhou Wenting, Margaret Million Samin, Srinivasan Sanjay, Kumari Neelam, Khalil Shibli, Su Chang, Jason Cheng
OBJECTIVE: To compare medical students' preference of smart phone television display (SPTD) to a slit-lamp teaching telescope (SLTT) in undergraduate clinical ophthalmology education. METHODS: This is a randomized, crossover, comparative study. Pairs of medical students were randomly assigned to 2 teaching sessions using either SPTD first followed by SLTT or in reverse order. Students were asked to give feedback on the 2 teaching devices by answering 6 questions using a numeric rating score from 1 to 10...
August 2017: Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
https://www.readbyqxmd.com/read/28765529/intracoronary-imaging-cholesterol-efflux-and-transcriptomics-after-intensive-statin-treatment-in-diabetes
#8
Surbhi Chamaria, Kipp W Johnson, Yuliya Vengrenyuk, Usman Baber, Khader Shameer, Aparna A Divaraniya, Benjamin S Glicksberg, Li Li, Samit Bhatheja, Pedro Moreno, Akiko Maehara, Roxana Mehran, Joel T Dudley, Jagat Narula, Samin K Sharma, Annapoorna S Kini
Residual atherothrombotic risk remains higher in patients with versus without diabetes mellitus (DM) despite statin therapy. The underlying mechanisms are unclear. This is a retrospective post-hoc analysis of the YELLOW II trial, comparing patients with and without DM (non-DM) who received rosuvastatin 40 mg for 8-12 weeks and underwent intracoronary multimodality imaging of an obstructive nonculprit lesion, before and after therapy. In addition, blood samples were drawn to assess cholesterol efflux capacity (CEC) and changes in gene expression in peripheral blood mononuclear cells (PBMC)...
August 1, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28722295/prevalence-correlates-and-impact-of-coronary-calcification-on-adverse-events-following-pci-with-newer-generation-des-findings-from-a-large-multiethnic-registry
#9
Robert S Copeland-Halperin, Usman Baber, Melissa Aquino, Anitha Rajamanickam, Swathi Roy, Choudhury Hasan, Nitin Barman, Jason C Kovacic, Pedro Moreno, Prakash Krishnan, Joseph M Sweeny, Roxana Mehran, George Dangas, Annapoorna S Kini, Samin K Sharma
OBJECTIVES: We sought to determine the prevalence, predictors, and clinical impact of target lesion calcification in patients undergoing percutaneous coronary intervention (PCI) with newer generation drug-eluting stents (DES) and devices. BACKGROUND: Coronary calcification is independently associated with adverse outcomes following PCI. While newer DES and contemporary devices are considered safer and more efficacious, their influence on outcomes following PCI of heavily calcified lesions is unknown...
July 19, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28719451/pancreatic-ductal-adenocarcinoma-with-high-radiotracer-uptake-in-68ga-prostate-specific-membrane-antigen-pet-ct
#10
Samine Sahbai, Petra Rieping, Christina Pfannenberg, Christian la Fougère, Matthias Reimold
Prostate-specific membrane antigen imaging with PET/CT is increasingly used in prostate cancer and was shown to have a high diagnostic performance. We report a clinical case of a 67-year-old man with previous history of operated prostate cancer and increasing prostate-specific antigen blood level. Ga-HBED-CC prostate-specific membrane antigen PET/CT imaging was indicated for the assessment of local recurrence and lymph node metastases of prostate cancer. In addition, a soft tissue mass in the body of the pancreas with high radiotracer uptake was detected...
July 17, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28704297/surgical-treatment-of-displaced-pediatric-lateral-condyle-fractures-of-the-humerus-by-the-posterior-approach
#11
William K Conaway, William L Hennrikus, Samine Ravanbakhsh, Zachary Winthrop, John Mahajan
The surgical approach for open reduction and internal fixation of lateral condyle fractures in children is controversial. Some authors recommend the lateral approach to the elbow over the posterior approach because of theoretical concern for injury to the vascular supply of the distal humerus and potential avascular necrosis (AVN). The purpose of this retrospective case series study is to report the outcomes of open reduction and internal fixation of displaced lateral condyle fractures of the humerus by the posterior approach...
July 12, 2017: Journal of Pediatric Orthopedics. Part B
https://www.readbyqxmd.com/read/28695354/mobile-health-clinic-for-the-medical-management-of-clinical-sequelae-experienced-by-survivors-of-the-2013-2016-ebola-virus-disease-outbreak-in-sierra-leone-west-africa
#12
R E Guetiya Wadoum, A Samin, N G Mafopa, M Giovanetti, G Russo, P Turay, J Turay, M Kargbo, M T Kanu, B Kargbo, J Akpablie, C J Cain, P Pasin, V Batwala, M S Sobze, M Potestà, A Minutolo, V Colizzi, C Montesano
An Ebola survivor Mobile Health Clinic (MHC) was established to implement lasting changes in communities it operates by providing effective and efficient mobile healthcare. After months of development, the MHC solution was operationalised in February 2015, aiming to provide integrated primary healthcare services to address the medical and psychosocial needs of Ebola virus (EBOV) survivors living in areas with low medical coverage. A total of 910 medical consultations for 246 EBOV survivors were performed between 7 February 2015 and 10 June 2016...
July 10, 2017: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/28675134/overview-of-the-infant-and-young-child-feeding-policy-environment-in-pakistan-federal-sindh-and-punjab-context
#13
Hana Mahmood, Yasmeen Suleman, Tabish Hazir, Durre Samin Akram, Shahadat Uddin, Michael J Dibley, Saleem Abassi, Amara Shakeel, Narjis Kazmi, Anne Marie Thow
BACKGROUND: Appropriate infant and young child feeding (IYCF) practices have been identified as important for appropriate child growth and development. (Ministry of Planning and Development, Ministry of National Health Services, Regulations and Coordination (2012)) Children in Pakistan still experience high rates of malnutrition, indicating a likely need for stronger IYCF policy. The purpose of this study was to identify major stakeholders who shape the IYCF policy environment and analyze which policies protect, promote and support IYCF practices, either directly or indirectly...
June 13, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28656738/mid-term-outcomes-of-consecutive-998-cases-of-coronary-atherectomy-in-contemporary-clinical-practice
#14
Nishtha Sareen, Usman Baber, Melissa Aquino, Sonny Sayseng, Joseph Sweeny, Nitin Barman, Vishal Kapur, Annapoorna Kini, Samin K Sharma
OBJECTIVES: To compare clinical and safety endpoints with use of rotational (RA) and orbital (OA) atherectomy in a large patient population with moderate to severely calcified lesions undergoing percutaneous coronary intervention (PCI). BACKGROUND: Coronary artery calcification (CAC) has been recognized as a risk factor for adverse outcomes with coronary artery disease (CAD). Though atheroablative techniques, RA and OA have been used extensively, comparison of their clinical and safety endpoints is lacking...
June 27, 2017: Journal of Interventional Cardiology
https://www.readbyqxmd.com/read/28649067/pharmacognostic-and-phytochemical-studies-of-zanthoxylum-armatum-dc
#15
- Barkatullah, Muhammad Ibrar, Naveed Muhammad, Ajmal Khan, Shahid Ali Khan, Salman Zafar, Samin Jan, Nadia Riaz, Zain Ullah, Umar Farooq, Javid Hussain
The pharmacognostic and phytochemical investigations on the leaf, stem bark, and fruit of Zanthoxylum armatum were carried out. Macroscopic study of leaf, stem bark, and fruit of Z. armatum revealed some of the characteristic features like size, shape, color, odor and taste of the crude drug. Distinguishing fragments were identified from the powder drug. Leaf, bark, and fruit powder of this plant have higher values of total, acid insoluble, and water soluble ash as compared to the powder of this plant exhausted with ethanol and n- hexane...
March 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28648438/recent-trends-in-epidemiology-of-dyslipidemias-in-india
#16
REVIEW
Rajeev Gupta, Ravinder S Rao, Anoop Misra, Samin K Sharma
Dyslipidemia is the most important atherosclerotic risk factor. Review of population based studies in India shows increasing mean total cholesterol levels. Recent studies have reported that high cholesterol is present in 25-30% of urban and 15-20% rural subjects. This prevalence is lower than high-income countries. The most common dyslipidemia in India are borderline high LDL cholesterol, low HDL cholesterol and high triglycerides. Studies have reported that over a 20-year period total cholesterol, LDL cholesterol and triglyceride levels have increased among urban populations...
May 2017: Indian Heart Journal
https://www.readbyqxmd.com/read/28631422/dispersive-micro-solid-phase-extraction-using-carbon-based-adsorbents-for-the-sensitive-determination-of-verapamil-in-plasma-samples-coupled-with-capillary-electrophoresis
#17
Abolghasem Jouyban, Samin Hamidi
A dispersive micro-solid-phase extraction procedure coupled with capillary electrophoresis ultraviolet detection was developed for determination of verapamil in plasma samples. Graphene oxide/polydopamin was synthesized by a one-step polymerization method, and graphene oxide/Fe3 O4 (magnetic graphene oxide) nanocomposite was prepared by coprecipitation method. Moreover, they were fully characterized. The use of hazardous and water-immiscible solvents was scaled down, and only 500 μL of acetone was required as the desorption solvent...
August 2017: Journal of Separation Science
https://www.readbyqxmd.com/read/28537607/colloid-oil-water-interface-interactions-in-the-presence-of-multiple-salts-charge-regulation-and-dynamics
#18
J C Everts, S Samin, N A Elbers, J E S van der Hoeven, A van Blaaderen, R van Roij
We theoretically and experimentally investigate colloid-oil-water-interface interactions of charged, sterically stabilized, poly(methyl-methacrylate) colloidal particles dispersed in a low-polar oil (dielectric constant ε = 5-10) that is in contact with an adjacent water phase. In this model system, the colloidal particles cannot penetrate the oil-water interface due to repulsive van der Waals forces with the interface whereas the multiple salts that are dissolved in the oil are free to partition into the water phase...
June 7, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28528289/platelet-hyperactivation-apoptosis-and-hypercoagulability-in-patients-with-acute-pulmonary-embolism
#19
Samin Rezania, Michael A Puskarich, Daniela N Petrusca, Evandro M Neto-Neves, Matthew T Rondina, Jeffrey A Kline
Changes in systemic redox balance can alter platelet activation and aggregation. Acute pulmonary embolism (PE) is a systematic inflammatory disease associated with mechanical shear stress, increased thrombin, catecholamines, serotonin and hemolysis, which cumulatively can hyperactivate platelets and accelerate their turnover. We tested the hypothesis that platelets from patients with moderately severe PE will show hyperstimulation and a pre-apoptotic phenotype associated with microparticles (MPs) in plasma...
July 2017: Thrombosis Research
https://www.readbyqxmd.com/read/28512668/prevalence-of-cancer-in-adult-patients-with-atopic-dermatitis-a-nationwide-study
#20
Samine Ruff, Alexander Egeberg, Yuki M F Andersen, Gunnar Gislason, Lone Skov, Jacob P Thyssen
No abstract text is available yet for this article.
May 17, 2017: Acta Dermato-venereologica
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