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https://www.readbyqxmd.com/read/29778318/quality-specifications-for-articles-of-botanical-origin-from-the-united-states-pharmacopeia
#1
Cuiying Ma, Hellen Oketch-Rabah, Nam-Cheol Kim, Maria Monagas, Anton Bzhelyansky, Nandakumara Sarma, Gabriel Giancaspro
BACKGROUND: In order to define appropriate quality of botanical dietary supplements, botanical drugs, and herbal medicines, the United States Pharmacopeia (USP) and the Herbal Medicines Compendium (HMC) contain science-based quality standards that include multiple interrelated tests to provide a full quality characterization for each article in terms of its identity, purity, and content. PURPOSE: To provide a comprehensive description of the pharmacopeial tests and requirements for articles of botanical origin in the aforementioned compendia...
April 10, 2018: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
https://www.readbyqxmd.com/read/29775867/phytochemical-profiles-phototoxic-and-antioxidant-properties-of-eleven-hypericum-species-a-comparative-study
#2
Edoardo Napoli, Laura Siracusa, Giuseppe Ruberto, Alessandra Carrubba, Silvia Lazzara, Antonio Speciale, Francesco Cimino, Antonella Saija, Mariateresa Cristani
Hypericum is one out of the nine genera belonging to the botanical family Clusiaceae Lindl (syn. Hypericaceae Juss.; APG III, 2009). The genus contains 484 species spread worldwide, one of which, Hypericum perforatum, is largely used in folk medicine. The aim of this study was to evaluate the chemical composition, along with the antioxidant and phototoxic activity, of 11 Hypericum species grown in Sicily (H. perforatum L., H. aegypticum L., H. androsaemum L., H. calycinum L., H. hircinum L., H. hirsutum L...
May 15, 2018: Phytochemistry
https://www.readbyqxmd.com/read/29751644/protective-effects-of-selected-botanical-agents-on-bone
#3
REVIEW
James Jam Jolly, Kok-Yong Chin, Ekram Alias, Kien Hui Chua, Ima Nirwana Soelaiman
Osteoporosis is a serious health problem affecting more than 200 million elderly people worldwide. The early symptoms of this disease are hardly detectable. It causes progressive bone loss, which ultimately renders the patients susceptible to fractures. Osteoporosis must be prevented because the associated fragility fractures result in high morbidity, mortality, and healthcare costs. Many plants used in herbal medicine contain bioactive compounds possessing skeletal protective effects. This paper explores the anti-osteoporotic properties of selected herbal plants, including their actions on osteoblasts (bone forming cells), osteoclasts (bone resorbing cells), and bone remodelling...
May 11, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29748977/paeonol-extracted-from-paeonia-suffruticosa-andr-ameliorated-uvb-induced-skin-photoaging-via-dld-nrf2-are-and-mapk-ap-1-pathway
#4
ZhengWang Sun, Juan Du, Eunson Hwang, Tae-Hoo Yi
Paeonia suffruticosa Andr. (PS) has been used in traditional Chinese medicine for a long time. However, there are no studies that investigate the preventive effects of PS on ultraviolet B (UVB)-induced photoaging. In this study, paeonol (PA) was detected the main compound in PS root. In vitro, PS and PA significantly inhibited UVB-induced phosphorylation of mitogen-activated protein kinase and activator protein 1 in keratinocytes, which consequently led to degradation of procollagen type I. On the other hand, PS and PA increased NAD(P)H:quinone oxidoreductase 1 and heme oxygenase-1 expression, confirmed by greater nuclear accumulation of nuclear factor E2-releated factor 2 (Nrf2)...
May 10, 2018: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/29740227/comparative-analysis-of-bioactive-phenolic-compounds-composition-from-26-medicinal-plants
#5
Oksana Sytar, Irene Hemmerich, Marek Zivcak, Cornelia Rauh, Marian Brestic
Bioactive phenolic compounds are powerful antioxidants in traditionally used medicinal and industrial crop plants and have attracted increased interest in the last years in their application and role in non-destructive methodology for pre-screening analysis of some stress factors. In this study the qualitative target was linked with future possible applications of received data for improving non-destructive methodology as well as for improving existing knowledge regarding antioxidant content in some plant species...
May 2018: Saudi Journal of Biological Sciences
https://www.readbyqxmd.com/read/29735755/recommended-approaches-for-pharmacokinetic-natural-product-drug-interaction-research-a-napdi-center-commentary
#6
Mary F Paine, Danny D Shen, Jeannine S McCune
Sales of botanical dietary supplements and other purported medicinal natural products (NPs) have escalated over the past ~25 years, increasing the potential for NPs to precipitate clinically significant pharmacokinetic interactions with United States Food and Drug Administration (FDA)-approved medications (NP-drug interactions or NPDIs). Published NPDI studies to date often lack consistency in design, implementation, and documentation, which present difficulties in assessing the clinical significance of the results...
May 7, 2018: Drug Metabolism and Disposition: the Biological Fate of Chemicals
https://www.readbyqxmd.com/read/29728134/ethnobotany-of-the-sierra-nevada-del-cocuy-g%C3%A3-ic%C3%A3-n-climate-change-and-conservation-strategies-in-the-colombian-andes
#7
Mireia Alcántara Rodríguez, Andrea Angueyra, Antoine M Cleef, Tinde Van Andel
BACKGROUND: The Sierra Nevada del Cocuy-Güicán in the Colombian Andes is protected as a National Natural Park since 1977 because of its fragile páramo ecosystems, extraordinary biodiversity, high plant endemism, and function as water reservoir. The vegetation on this mountain is threatened by expanding agriculture, deforestation, tourism, and climate change. We present an ethnobotanical inventory among local farmer communities and discuss the effects of vegetation change on the availability of useful plants...
May 5, 2018: Journal of Ethnobiology and Ethnomedicine
https://www.readbyqxmd.com/read/29728034/-development-of-indel-markers-for-molecular-authentication-of-panax-ginseng-and-p-quinquefolius
#8
Rong-Bo Wang, Hui-Li Tian, Hong-Tao Wang, Gui-Sheng Li
Panax ginseng and P. quinquefolius are two kinds of important medicinal herbs. They are morphologically similar but have different pharmacological effects. Therefore, botanical origin authentication of these two ginsengs is of great importance for ensuring pharmaceutical efficacy and food safety. Based on the fact that intron position in orthologous genes is highly conserved across plant species, intron length polymorphisms were exploited from unigenes of ginseng. Specific primers were respectively designed for these two species based on their insertion/deletion sequences of cytochrome P450 and glyceraldehyde 3-phosphate dehydrogenase, and multiplex PCR was conducted for molecular authentication of P...
April 2018: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29727721/natural-occurrence-of-genotoxic-and-carcinogenic-alkenylbenzenes-in-indonesian-jamu-and-evaluation-of-consumer-risks
#9
Suparmi Suparmi, Diana Widiastuti, Sebastiaan Wesseling, Ivonne M C M Rietjens
The consumer risks of jamu, Indonesian traditional herbal medicines, was assessed focussing on the presence of alkenylbenzene containing botanical ingredients. Twenty-three out of 25 samples contained alkenylbenzenes at levels ranging from 3.8 to 440 μg/kg, with methyleugenol being the most frequently encountered alkenylbenzene. The estimated daily intake (EDI) resulting from jamu consumption was estimated to amount to 0.2-171 μg/kg bw/day for individual alkenylbenzenes, to 0.9-203 μg/kg bw/day when adding up all alkenylbenzenes detected, and to 0...
May 1, 2018: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/29709646/cytotoxicity-of-18-cameroonian-medicinal-plants-against-drug-sensitive-and-multi-factorial-drug-resistant-cancer-cells
#10
Armelle T Mbaveng, Hermione T Manekeng, Gaelle S Nguenang, Joachim K Dzotam, Victor Kuete, Thomas Efferth
ETHNOPHARMACOLOGICAL RELEVANCE: Recommendations have been made stating that ethnopharmacological usages such as immune and skin disorders, inflammatory, infectious, parasitic and viral diseases should be taken into account if selecting plants for anticancer screening, since these reflect disease states bearing relevance to cancer or cancer-like symptoms. Cameroonian medicinal plants investigated in this work are traditionally used to treat cancer or ailments with relevance to cancer or cancer-like symptoms...
April 27, 2018: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29708295/the-safety-of-st-john-s-wort-hypericum-perforatum-in-pregnancy-and-lactation-a-systematic-review-of-rodent-studies
#11
REVIEW
Catharine Avila, Dawn Whitten, Sue Evans
Herbal products are popular among women during the perinatal period. St John's wort (SJW), Hypericum perforatum, is a common remedy for mild depression, a problem prevalent in this population. Although the safety of herbal products must be investigated, ethical issues constrain intervention studies in humans. Hence, animal studies often inform clinical decisions. The objective of this study is to systematically review rodent studies assessing the safety of SJW during the perinatal period. A literature search to November 10, 2017, identified 10 rodent studies that met a priori inclusion criteria...
April 30, 2018: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/29705516/icones-plantarum-malabaricarum-early-18th-century-botanical-drawings-of-medicinal-plants-from-colonial-ceylon
#12
Tinde Van Andel, Ariane Scholman, Mieke Beumer
ETHNOPHARMACOLOGICAL RELEVANCE: From 1640-1796, the Dutch East India Company (VOC) occupied the island of Ceylon (now Sri Lanka). Several VOC officers had a keen interest in the medicinal application of the local flora. The Leiden University Library holds a two-piece codex entitled: Icones Plantarum Malabaricarum, adscriptis nominibus et viribus, Vol. I. & II. (Illustrations of Plants from the Malabar, assigned names and strength). This manuscript contains 262 watercolour drawings of medicinal plants from Sri Lanka, with handwritten descriptions of local names, habitus, medicinal properties and therapeutic applications...
April 27, 2018: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29701283/therapeutic-effect-of-northern-labrador-tea-extracts-for-acute-myeloid-leukemia
#13
Colin M McGill, Patrick L Tomco, Regina M Ondrasik, Kaitlyn C Belknap, Gaelen K Dwyer, Daniel J Quinlan, Thomas A Kircher, Cheryl P Andam, Timothy J Brown, David F Claxton, Brian M Barth
Acute myeloid leukemia (AML) is an aggressive hematological malignancy that is one of the more common pediatric malignancies in addition to occurring with high incidence in the aging population. Unfortunately, these patient groups are quite sensitive to toxicity from chemotherapy. Northern Labrador tea, or Rhododendron tomentosum Harmaja (a.k.a. Ledum palustre subsp. decumbens) or "tundra tea," is a noteworthy medicinal plant used by indigenous peoples in Alaska, Canada, and Greenland to treat a diversity of ailments...
April 27, 2018: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/29690891/palikur-traditional-roundwood-construction-in-eastern-french-guiana-ethnobotanical-and-cultural-perspectives
#14
Clémence Ogeron, Guillaume Odonne, Antonia Cristinoi, Julien Engel, Pierre Grenand, Jacques Beauchêne, Bruno Clair, Damien Davy
BACKGROUND: Palikur Amerindians live in the eastern part of French Guiana which is undergoing deep-seated changes due to the geographical and economic opening of the region. So far, Palikur's traditional ecological knowledge is poorly documented, apart from medicinal plants. The aim of this study was to document ethnobotanical practices related to traditional construction in the region. METHODS: A combination of qualitative and quantitative methods was used. Thirty-nine Palikur men were interviewed in three localities (Saint-Georges de l'Oyapock, Regina and Trois-Palétuviers) between December 2013 and July 2014...
April 24, 2018: Journal of Ethnobiology and Ethnomedicine
https://www.readbyqxmd.com/read/29676110/-species-diversity-of-ex-situ-cultivated-chinese-medicinal-plants
#15
Ling Que, Xiu-Lian Chi, Chun-Xin Zang, Yu Zhang, Min Chen, Guang Yang, An-Qi Jin
Ex-situ conservation is an important means to protect biological genetic resources. Resource protection has received more and more attention with the continuous improvement of the comprehensive utilization of traditional Chinese medicine resources. In this paper, the research and compilation of the species list of ex-situ cultivated medicinal plants in 12 Chinese Academy of Sciences botanic gardens and 19 specialized medicinal botanic gardens in China were carried out. Based on the Species 2000(2017) and other classification databases, species diversity of medicinal plants ex-situ cultivated in these botanical gardens were analyzed...
March 2018: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29674964/botanical-provenance-of-traditional-medicines-from-carpathian-mountains-at-the-ukrainian-polish-border
#16
REVIEW
Weronika Kozlowska, Charles Wagner, Erin M Moore, Adam Matkowski, Slavko Komarnytsky
Plants were an essential part of foraging for food and health, and for centuries remained the only medicines available to people from the remote mountain regions. Their correct botanical provenance is an essential basis for understanding the ethnic cultures, as well as for chemical identification of the novel bioactive molecules with therapeutic effects. This work describes the use of herbal medicines in the Beskid mountain ranges located south of Krakow and Lviv, two influential medieval centers of apothecary tradition in the region...
2018: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/29674230/association-of-herbal-botanic-supplement-use-with-quality-of-life-recurrence-and-survival-in-newly-diagnosed-stage-ii-colon-cancer-patients-a-2-y-follow-up-study
#17
Qiran Chen, Pengcheng Xun, Cari Lewis Tsinovoi, Beate Henschel, Alyce D Fly, Ka He
OBJECTIVES: Our objective was to investigate the association between herbal/botanic supplement use and perceived quality of life (QoL), cancer recurrence, and all-cause mortality in colon cancer patients. METHODS: Patients (n = 453) newly diagnosed with stage II adenocarcinoma of the colon between 2009 and 2011 were recruited from the North Carolina Central Cancer Registry. Data including demographic variables, herbal medicine use and frequency, lifestyle, diet, cancer treatment, and QoL were collected by interviews at diagnosis (baseline) and 1 and 2 y after diagnosis...
February 13, 2018: Nutrition
https://www.readbyqxmd.com/read/29672820/a-review-of-the-toxicity-of-compounds-found-in-herbal-dietary-supplements
#18
Amy Hudson, Elizabeth Lopez, Ahmad J Almalki, Amy L Roe, Angela I Calderón
Use of herbal dietary supplements by the public is common and has been happening for centuries. In the United States, the Food and Drug Administration has a limited scope of regulation over marketed herbal dietary supplements, which may contain toxic botanical compounds that pose a public health risk. While the Food and Drug Administration has made efforts to prohibit the sale of unsafe herbal dietary supplements, numerous reports have proliferated of adverse events due to these supplements. This literature review investigates bioactive plant compounds commonly used in herbal dietary supplements and their relative toxicities...
April 19, 2018: Planta Medica
https://www.readbyqxmd.com/read/29629295/-in-vivo-anti-arthritic-and-anti-nociceptive-effects-of-ethanol-extract-of-moringa-oleifera-leaves-on-complete-freund-s-adjuvant-cfa-induced-arthritis-in-rats
#19
Harith Jameel Mahdi, Nurzalina Abdul Karim Khan, Mohd Zaini Bin Asmawi, Roziahanim Mahmud, Vikneswaran A/L Murugaiyah
Background: The medicinal uses of plants are in many cases based exclusively on traditional knowledge without enough scientific evidences. Different parts of Moringa oleifera were traditionally used for the treatment of wide variety of ailments including arthritis and joints pain. The present study had been designed to evaluate the anti-arthritic and anti-nociceptive activities of ethanol extract of Moringa leaves, this being the most abundant plant part suitable for commercial mass production of botanical medicinal products...
March 2018: Integrative Medicine Research
https://www.readbyqxmd.com/read/29629064/plantago-major-in-traditional-persian-medicine-and-modern-phytotherapy-a-narrative-review
#20
REVIEW
Younes Najafian, Shokouh Sadat Hamedi, Masoumeh Kaboli Farshchi, Zohre Feyzabadi
Plantago major has been used widely since ancient times, to manage a wide range of diseases including constipation, coughs and wounds. The aim of this study is to review the traditional application, botanical characterization, pharmacological activities, phytochemistry effects and toxicity of Plantago major. In this review study, medicinal properties of Plantago major are collected from credible pharmacopeias, textbooks of traditional Persian medicine (TPM) belonging to the 10-18th century AD, such as "The Canon of Medicine", "Makhzan-Al- Advia" and so on...
February 2018: Electronic Physician
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