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https://www.readbyqxmd.com/read/28092098/evaluation-the-ethnopharmacological-studies-in-iran-during-2004-2016-a-systematic-review
#1
REVIEW
Zahra Sadeghi, Maryam Akaberi, Seyed Ahmad Emami, Alireza Sobhkhizi, Amirhossein Sahebkar
Although Iran has a deep history in herbal medicine and great heritage of ancient medical scholars, few efforts have been made to evaluate ethnopharmacological aspects of medicinal plants in this country. In the present study, the authors have reviewed all important literature about the ethnopharmacological investigations on medicinal plants used in the last decade in Iran. All provinces of Iran were categorized according to a phytogeographical division. Information was collected through bibliographic investigations from scientific journals and books...
January 16, 2017: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/28088492/pikuni-blackfeet-traditional-medicine-neuroprotective-activities-of-medicinal-plants-used-to-treat-parkinson-s-disease-related-symptoms
#2
Aurélie de Rus Jacquet, Mitali Arun Tambe, Sin Ying Ma, George P McCabe, Jay Hansford C Vest, Jean-Christophe Rochet
ETHNOPHARMACOLOGICAL RELEVANCE: Parkinson's disease (PD) is a multifactorial neurodegenerative disorder affecting 5% of the population over the age of 85 years. Current treatments primarily involve dopamine replacement therapy, which leads to temporary relief of motor symptoms but fails to slow the underlying neurodegeneration. Thus, there is a need for safe PD therapies with neuroprotective activity. In this study, we analyzed contemporary herbal medicinal practices used by members of the Pikuni-Blackfeet tribe from Western Montana to treat PD-related symptoms, in an effort to identify medicinal plants that are affordable to traditional communities and accessible to larger populations...
January 11, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28076407/medicinal-plant-diversity-and-inter-cultural-interactions-between-indigenous-guarani-criollos-and-polish-migrants-in-the-subtropics-of-argentina
#3
Monika Kujawska, Norma I Hilgert, Héctor A Keller, Guillermo Gil
Numerous studies highlight the importance of phytotherapy for indigenous and non-indigenous people in different parts of the world. In this work we analyze the richness (number of species), diversity (plant identity and the number of illnesses for which it is used) and similarity of plant species and illnesses treated with them, in order to contribute new data and insight into the importance of plant medicines to the local medical systems of people living in Misiones province, in the subtropics of Argentina...
2017: PloS One
https://www.readbyqxmd.com/read/28075584/review-of-medicinal-and-aromatic-plants-industrial-profiles-volume-48-sesame-the-genus-sesamum-medicinal-and-aromatic-plants-industrial-profiles-volume-48-sesame-the-genus-sesamum-edited-by-d-bedigian-missouri-botanical-garden-st-louis-missouri-crc-press-taylor
#4
https://www.readbyqxmd.com/read/28068355/a-methodology-for-cancer-therapeutics-by-systems-pharmacology-based-analysis-a-case-study-on-breast-cancer-related-traditional-chinese-medicines
#5
Yan Li, Jinghui Wang, Feng Lin, Yinfeng Yang, Su-Shing Chen
Breast cancer is the most common carcinoma in women. Comprehensive therapy on breast cancer including surgical operation, chemotherapy, radiotherapy, endocrinotherapy, etc. could help, but still has serious side effect and resistance against anticancer drugs. Complementary and alternative medicine (CAM) may avoid these problems, in which traditional Chinese medicine (TCM) has been highlighted. In this section, to analyze the mechanism through which TCM act on breast cancer, we have built a virtual model consisting of the construction of database, oral bioavailability prediction, drug-likeness evaluation, target prediction, network construction...
2017: PloS One
https://www.readbyqxmd.com/read/28068280/landolphia-owariensis-attenuates-alcohol-induced-cerebellar-neurodegeneration-significance-of-neurofilament-protein-alteration-in-the-purkinje-cells
#6
Charles A Oyinbo, Patrick S Igbigbi, Godwin O Avwioro
BACKGROUND: Alcohol-induced cerebellar neurodegeneration is a neuroadaptation that is associated with chronic alcohol abuse. Conventional drugs have been largely unsatisfactory in preventing neurodegeneration. Yet, multimodal neuro-protective therapeutic agents have been hypothesised to have high therapeutic potential for the treatment of CNS conditions; there is yet a dilemma of how this would be achieved. Contrarily, medicinal botanicals are naturally multimodal in their mechanism of action...
December 1, 2016: Folia Medica
https://www.readbyqxmd.com/read/28043897/natural-products-against-alzheimer-s-disease-pharmaco-therapeutics-and-biotechnological-interventions
#7
REVIEW
Abhijit Dey, Raktim Bhattacharya, Anuradha Mukherjee, Devendra Kumar Pandey
Alzheimer's disease (AD) is a severe, chronic and progressive neurodegenerative disease associated with memory and cognition impairment ultimately leading to death. It is the commonest reason of dementia in elderly populations mostly affecting beyond the age of 65. The pathogenesis is indicated by accumulation of the amyloid-beta (Aβ) plaques and neurofibrillary tangles (NFT) in brain tissues and hyperphosphorylation of tau protein in neurons. The main cause is considered to be the formation of reactive oxygen species (ROS) due to oxidative stress...
December 30, 2016: Biotechnology Advances
https://www.readbyqxmd.com/read/28038955/traditional-chinese-medicine-for-pulmonary-fibrosis-therapy-progress-and-future
#8
REVIEW
Liu-Cheng Li, Lian-Di Kan
ETHNOPHARMACOLOGICAL RELEVANCE: Pulmonary fibrosis (PF) is a chronic, debilitating and often lethal lung disorder. Despite the molecular mechanisms of PF are gradually clear with numerous researchers' efforts, few effective drugs have been developed to reverse human PF or even halt the chronic progression to respiratory failure. Traditional Chinese medicine (TCM), the main component of the medical practice used for more than 5000 years especially in China, often exerts wider action spectrum than previously attempted options in treating human diseases...
December 27, 2016: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28025163/use-of-medicinal-plants-by-health-professionals-in-mexico
#9
Angel Josabad Alonso-Castro, Fabiola Domínguez, Juan José Maldonado-Miranda, Luis Jesús Castillo-Pérez, Candy Carranza-Álvarez, Eloy Solano, Mario Alberto Isiordia-Espinoza, María Del Carmen Juárez-Vázquez, Juan Ramón Zapata-Morales, Marco Antonio Argueta-Fuertes, Alan Joel Ruiz-Padilla, César Rogelio Solorio-Alvarado, Joceline Estefanía Rangel-Velázquez, Rolffy Ortiz-Andrade, Ignacio González-Sánchez, Gustavo Cruz-Jiménez, Luis Manuel Orozco-Castellanos
ETHNOPHARMACOLOGICAL RELEVANCE: The use of medicinal plants in Mexico has been documented since pre-Hispanic times. Nevertheless, the level of use of medicinal plants by health professionals in Mexico remains to be explored. AIM OF THE STUDY: To evaluate the use, acceptance and prescription of medicinal plants by health professionals in 9 of the states of Mexico MATERIALS AND METHODS: Direct and indirect interviews, regarding the use and acceptance of medicinal plants, with health professionals (n=1614), including nurses, physicians, pharmacists, and odontologists from nine states in Mexico were performed from January 2015 to July 2016...
December 23, 2016: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/27999287/simultaneous-qualitation-and-quantitation-of-chlorogenic-acids-in-kuding-tea-using-ultra-high-performance-liquid-chromatography-diode-array-detection-coupled-with-linear-ion-trap-orbitrap-mass-spectrometer
#10
Yanyun Che, Zhibin Wang, Zhiyun Zhu, Yangyang Ma, Yaqiong Zhang, Wen Gu, Jiayu Zhang, Gaoxiong Rao
Kuding tea, the leaves of Ilex Kudingcha C.J. Tseng, has been applied for treating obesity, hypertension, cardiovascular disease, hyperlipidemia, and so on. The chlorogenic acids (CGAs) in Kuding tea have shown excellent antioxidative, antiobesity, anti-atherosclerotic and anticancer activities. Nevertheless, the chemical profiles of CGAs in Kuding tea have not been comprehensively studied yet, which hinders further quality control. In the present study, a sensitive ultra-high-performance liquid chromatography-diode array detection coupled with a linear ion trap-Orbitrap (UHPLC-DAD-LTQ-Orbitrap) method was established to screen and identify CGAs in Kuding tea...
December 16, 2016: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/27975375/complexity-synergy-endophytes-and-more-addressing-the-challenges-of-botanical-medicine-research
#11
N B Cech
No abstract text is available yet for this article.
December 2016: Planta Medica
https://www.readbyqxmd.com/read/27894973/is-there-nothing-new-under-the-sun-the-influence-of-herbals-and-pharmacopoeias-on-ethnobotanical-traditions-in-albacete-spain
#12
Diego Rivera, Alonso Verde, Concepción Obón, Francisco Alcaraz, Candelaria Moreno, Teresa Egea, José Fajardo, José Antonio Palazón, Arturo Valdés, Maria Adele Signorini, Piero Bruschi
ETHNOPHARMACOLOGICAL RELEVANCE: This paper has two overarching aims: (1) presenting the results of studying the Albacete tariff of medicines of 1526 and (2) broadly analyzing the origin and influences of medicinal traditional knowledge in the region of Albacete, Spain. We use historical and modern literature that may have influenced this knowledge. Our primary goal was to determine the ingredients used in the pharmacy in the 16th century CE in Albacete through the analysis of the tariff, and our secondary goal was to investigate until when ingredients and uses present in pharmacy and herbals persisted in later periods...
January 4, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/27890584/a-sedge-plant-as-the-source-of-kangaroo-island-propolis-rich-in-prenylated-p-coumarate-ester-and-stilbenes
#13
Colin C Duke, Van H Tran, Rujee K Duke, Abdallah Abu-Mellal, George T Plunkett, Douglas I King, Kaiser Hamid, Karen L Wilson, Russell L Barrett, Jeremy J Bruhl
Propolis samples from Kangaroo Island, South Australia, were investigated for chemical constituents using high-field nuclear magnetic resonance spectral profiling. A type of propolis was found containing a high proportion of prenylated hydroxystilbenes. Subsequently, the botanical origin of this type of propolis was identified using a beehive propolis depletion method and analysis of flora. Ligurian honey bees, Apis mellifera ligustica Spinola, were found to produce propolis from resin exuded by the Australian native sedge plant Lepidosperma sp...
February 2017: Phytochemistry
https://www.readbyqxmd.com/read/27866010/the-botanical-explorer-s-legacy-a-promising-bioprospecting-tool
#14
Axel Helmstädter
Records about the traditional uses of medicinal plants can be considered useful in bioprospecting (i.e., the search for new active agents or lead structures in nature). Several sources like Egyptian papyri, early modern herbals and pharmacopoeias have been studied in this respect. It is proposed to use recordings of botanically interested explorers of the 19th and early 20th centuries as well. Some of them give detailed information about traditionally used medicinal plants and analysis shows that a considerable number of these have never been scientifically investigated...
November 16, 2016: Drug Discovery Today
https://www.readbyqxmd.com/read/27865796/bletilla-striata-medicinal-uses-phytochemistry-and-pharmacological-activities
#15
REVIEW
Xirui He, Xiaoxiao Wang, Jiacheng Fang, Zefeng Zhao, Linhong Huang, Hao Guo, Xiaohui Zheng
ETHNOPHARMACOLOGICAL RELEVANCE: Bletilla striata (Thunb.) Reichb. f. (Orchidaceae), also known as Hyacinth Orchid and Baiji (Simplified Chinese: ), not only has been widely used for the treatment of hematemesis, hemoptysis, and traumatic bleeding due to the efficacy of arresting bleeding with astringent action, but also has been applied topically to overcome ulcers, sores, swellings, and chapped skin due to the efficacy of dispersing swelling and promoting tissue regeneration. Additional medical applications include the treatment of tuberculosis, malignant ulcers, hemorrhoids, anthrax, eye diseases, and silicosis...
January 4, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/27857157/inhibiting-mdsc-differentiation-from-bone-marrow-with-phytochemical-polyacetylenes-drastically-impairs-tumor-metastasis
#16
Wen-Chi Wei, Sheng-Yen Lin, Chun-Wen Lan, Yu-Chen Huang, Chih-Yu Lin, Pei-Wen Hsiao, Yet-Ran Chen, Wen-Chin Yang, Ning-Sun Yang
Myeloid-derived suppressor cells (MDSCs) are implicated in the promotion of tumor metastasis by protecting metastatic cancerous cells from immune surveillance and have thus been suggested as novel targets for cancer therapy. We demonstrate here that oral feeding with polyacetylenic glycosides (BP-E-F1) from the medicinal plant Bidens pilosa effectively suppresses tumor metastasis and inhibits tumor-induced accumulation of granulocytic (g) MDSCs, but does not result in body weight loss in a mouse mammary tumor-resection model...
November 18, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27843675/evidence-for-the-paleoethnobotany-of-the-neanderthal-a-review-of-the-literature
#17
REVIEW
Gerhard P Shipley, Kelly Kindscher
Our perception of our closest human relatives, the Neanderthals, has evolved in the last few decades from brutish ape-men to intelligent archaic human peoples. Our understanding and appreciation of their cultural sophistication has only recently extended to their diet. Only within the last few years, with new techniques and a shift in focus, have we begun to truly investigate and understand the role of plants in their diet and culture. The more we learn about Neanderthals, the more we realize that biological and cultural distinctions between them and us were relatively small...
2016: Scientifica
https://www.readbyqxmd.com/read/27834307/effects-of-tanshinone-nanoemulsion-and-extract-on-inhibition-of-lung-cancer-cells-a549
#18
W D Lee, Y J Liang, B H Chen
Danshen (Salvia miltiorrhiza), a Chinese medicinal herb, consists of several functional components including tanshinones responsible for prevention of several chronic diseases. This study intends to prepare tanshinone extract and nanoemulsion from danshen and determine their inhibition effect on lung cancer cells A549. A highly stable tanshinone nanoemulsion composed of Capryol 90, Tween 80, ethanol and deionized water with the mean particle size of 14.2 nm was successfully prepared. Tanshinone nanoemulsion was found to be more effective in inhibiting A549 proliferation than tanshinone extract...
December 9, 2016: Nanotechnology
https://www.readbyqxmd.com/read/27829985/potential-therapeutic-strategies-for-hypertension-exacerbated-cardiotoxicity-of-anticancer-drugs
#19
REVIEW
Robin K Kuriakose, Rakesh C Kukreja, Lei Xi
Despite their recognized cardiotoxic effects, anthracyclines remain an essential component in many anticancer regimens due to their superior antitumor efficacy. Epidemiologic data revealed that about one-third of cancer patients have hypertension, which is the most common comorbidity in cancer registries. The purpose of this review is to assess whether anthracycline chemotherapy exacerbates cardiotoxicity in patients with hypertension. A link between hypertension comorbidity and anthracycline-induced cardiotoxicity (AIC) was first suggested in 1979...
2016: Oxidative Medicine and Cellular Longevity
https://www.readbyqxmd.com/read/27802026/magnetic-microbead-affinity-selection-screening-magmass-of-botanical-extracts-for-inhibitors-of-15-lipoxygenase
#20
Michael D Rush, Elisabeth M Walker, Tristesse Burton, Richard B van Breemen
To expedite the identification of active natural products in complex mixtures such as botanical extracts, a magnetic microbead affinity selection screening (MagMASS) procedure was developed. This technique utilizes target proteins immobilized on magnetic beads for rapid bioaffinity isolation of ligands from complex mixtures. A MagMASS method was developed and validated for 15-lipoxygenase. As a proof of concept, several North American prairie plants used medicinally by Native Americans were extracted with MeOH and screened...
November 23, 2016: Journal of Natural Products
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