Vitória S Fahed, Emer P Doheny, Carla Collazo, Joanna Krzysztofik, Elliot Mann, Philippa Morgan-Jones, Laura Mills, Cheney Drew, Anne E Rosser, Rebecca Cousins, Grzegorz Witkowski, Esther Cubo, Monica Busse, Madeleine M Lowery
PURPOSE: Changes in voice and speech are characteristic symptoms of Huntington's disease (HD). Objective methods for quantifying speech impairment that can be used across languages could facilitate assessment of disease progression and intervention strategies. The aim of this study was to analyze acoustic features to identify language-independent features that could be used to quantify speech dysfunction in English-, Spanish-, and Polish-speaking participants with HD. METHOD: Ninety participants with HD and 83 control participants performed sustained vowel, syllable repetition, and reading passage tasks recorded with previously validated methods using mobile devices...
March 26, 2024: American Journal of Speech-language Pathology