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Epidemiology diabetic foot

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https://www.readbyqxmd.com/read/28682679/influence-of-epidemiologic-and-patient-behavior-related-predictors-on-amputation-rates-in-diabetic-patients-systematic-review-and-meta-analysis
#1
Jin Yong Shin, Si-Gyun Roh, Nae-Ho Lee, Kyung-Moo Yang
Amputation of patients with diabetic foot is a major issue worldwide, particularly from a medical and economic standpoint. This meta-analysis aimed to identify significant risk factors of high amputation rate among epidemiologic and patient behavior-related predictors in diabetic patients. A systematic literature review and meta-analysis were performed using MEDLINE, EMBASE, and Cochrane databases. Seven variables were extracted from the included studies and evaluated based on amputation rate. The Newcastle-Ottawa scale was used to assess the quality of the studies...
March 2017: International Journal of Lower Extremity Wounds
https://www.readbyqxmd.com/read/28664412/early-use-of-ceftaroline-fosamil-in-the-united-states-veterans-health-care-system
#2
Rachel S Britt, Kirk E Evoy, Grace C Lee, Kelly R Reveles, Kimberly M Sorensen, Xavier Jones, Mary Bollinger, Christopher R Frei
BACKGROUND: Ceftaroline fosamil is US Food and Drug Administration-approved for acute bacterial skin and skin structure infections and community-acquired bacterial pneumonia, but it is not known how ceftaroline is being used in real-world settings or how adverse effects (AEs) and mortality compare to clinical trials. OBJECTIVE: This study describes ceftaroline use, AEs, and mortality in US Veterans Health Administration (VHA) hospital patients. METHODS: This phase IV, population-based, epidemiologic study analyzed patients ≥18 years old who received one or more ceftaroline doses within 14 days of admission to 69 VHA hospitals in 41 US states/territories from 1 October 2010 to 30 September 2014...
August 2017: Drugs
https://www.readbyqxmd.com/read/28521817/epidemiology-of-diabetic-foot-disease-and-diabetes-related-lower-extremity-amputation-in-australia-a-systematic-review-protocol
#3
Jaap J van Netten, Mendel Baba, Peter A Lazzarini
BACKGROUND: Diabetic foot disease is associated with major morbidity, mortality, costs, and reduction of a person's quality of life. Investigating the epidemiology of diabetic foot disease is the backbone of diabetic foot research and clinical practice, yet the full burden of diabetic foot disease in Australia is unknown. This study aims to describe the protocol for a systematic review of the epidemiology of diabetic foot disease and diabetes-related lower-extremity amputation in Australia...
May 18, 2017: Systematic Reviews
https://www.readbyqxmd.com/read/28495817/estimating-the-prevalence-hospitalisation-and-mortality-from-type-2-diabetes-mellitus-in-nigeria-a-systematic-review-and-meta-analysis
#4
Davies Adeloye, Janet O Ige, Adewale V Aderemi, Ngozi Adeleye, Emmanuel O Amoo, Asa Auta, Gbolahan Oni
BACKGROUND: There is not yet a comprehensive evidence-based epidemiological report on type 2 diabetes mellitus (T2DM) in Nigeria. We aimed to estimate country-wide and zonal prevalence, hospitalisation and mortality rates of T2DM in Nigeria. METHODS: We searched MEDLINE, EMBASE, Global Health, Africa Journals Online (AJOL) and Google Scholar for population and hospital-based studies on T2DM in Nigeria. We conducted a random-effects meta-analysis on extracted crude estimates, and applied a meta-regression epidemiological model, using the United Nations demographics for Nigeria in 1990 and 2015 to determine estimates of diabetes in Nigeria for the two years...
May 11, 2017: BMJ Open
https://www.readbyqxmd.com/read/28465790/osteomyelitis-in-diabetic-foot-a-comprehensive-overview
#5
REVIEW
Laura Giurato, Marco Meloni, Valentina Izzo, Luigi Uccioli
Foot infection is a well recognized risk factor for major amputation in diabetic patients. The osteomyelitis is one of the most common expression of diabetic foot infection, being present approximately in present in 10%-15% of moderate and in 50% of severe infectious process. An early and accurate diagnosis is required to ensure a targeted treatment and reduce the risk of major amputation. The aim of this review is to report a complete overview about the management of diabetic foot osteomyelitis. Epidemiology, clinical aspects, diagnosis and treatment are widely described according to scientific reccomendations and our experience...
April 15, 2017: World Journal of Diabetes
https://www.readbyqxmd.com/read/28442913/fracture-risk-in-patients-with-type-2-diabetes-mellitus-and-possible-risk-factors-a-systematic-review-and-meta-analysis
#6
REVIEW
Ardeshir Moayeri, Mahmoud Mohamadpour, Seyedeh Fatemeh Mousavi, Ehsan Shirzadpour, Safoura Mohamadpour, Mansour Amraei
AIM: Patients with type 2 diabetes mellitus (T2DM) have an increased risk of bone fractures. A variable increase in fracture risk has been reported depending on skeletal site, diabetes duration, study design, insulin use, and so on. The present meta-analysis aimed to investigate the association between T2DM with fracture risk and possible risk factors. METHODS: Different databases including PubMed, Institute for Scientific Information, and Scopus were searched up to May 2016...
2017: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/28409160/peripheral-and-autonomic-neuropathy-in-south-asians-and-white-caucasians-with-type-2-diabetes-mellitus-possible-explanations-for-epidemiological-differences
#7
Abd A Tahrani, Q A Altaf, Milan K Piya, Anthony H Barnett
Objectives. To compare the prevalence of diabetic peripheral neuropathy (DPN) and that of cardiac autonomic neuropathy (CAN) between South Asians and White Caucasians with type 2 diabetes and to explore reasons for observed differences. Methods. A cross-sectional study of casually selected South Asian and White Caucasian adults attending a hospital-based diabetes clinic in the UK. DPN and CAN were assessed using the Michigan Neuropathy Screening Instrument (MNSI) and heart rate variability testing, respectively...
2017: Journal of Diabetes Research
https://www.readbyqxmd.com/read/28387897/prevalence-of-type-2-diabetes-in-the-arab-world-impact-of-gdp-and-energy-consumption
#8
S A Meo, A M Usmani, E Qalbani
OBJECTIVE: Diabetes Mellitus (DM) is a rapidly growing and most challenging health issue of the 21st century. This study aimed to investigate the prevalence of type-2 DM and its association with Gross Domestic Product (GDP) and energy consumption in the Arab world countries. MATERIALS AND METHODS: We identified 88 articles through systematic searches including Institute of Scientific Information (ISI) Web of Science, PubMed and EMBASE databases published between 1980-2015...
March 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28191040/moisturisers-for-the-treatment-of-foot-xerosis-a-systematic-review
#9
REVIEW
Justin Parker, Rolf Scharfbillig, Sara Jones
BACKGROUND: Xerosis, literally dryness of the skin, of the foot is a common condition encountered clinically, which can lead to discomfort and predisposition to infection. Currently, there are no evidence-based recommendations on which moisturiser formulations best alleviate xerotic symptoms. The aim of this review was to guide clinical practice in the treatment of primary and diabetes related foot xerosis, by identifying from the existing literature the most effective ingredient or formulation of topical treatments for symptoms of primary foot xerosis in the general population...
2017: Journal of Foot and Ankle Research
https://www.readbyqxmd.com/read/28166662/-ischemic-origin-of-diabetic-foot-disease-epidemiology-difficulties-of-diagnosis-options-for-prevention-and-revascularization
#10
REVIEW
Endre Kolossváry, Zoltán Bánsághi, Gábor Viktor Szabó, Zoltán Járai, Katalin Farkas
"Diabetic foot" as definition covers a multifactorial clinical condition. According to the recent epidemiological data, the role of lower limb ischemia is getting more influential over other pathological causes, like neuropathy, infections and bone or soft tissue deformity. In diabetes, vascular disease leads to increased risk for leg ulcers and minor or major amputations. The traditional diagnostic tools for recognition of peripheral arterial disease have limited value because of diabetes specific clinical manifestations...
February 2017: Orvosi Hetilap
https://www.readbyqxmd.com/read/28009675/effects-of-foot-and-ankle-devices-on-balance-gait-and-falls-in-adults-with-sensory-perception-loss-a-systematic-review
#11
Joanne Paton, Anna L Hatton, Keith Rome, Bridie Kent
BACKGROUND: Foot and ankle devices are being developed as a method of preventing people with sensory perception loss sustaining a fall. Such devices are believed to work by reducing the likelihood of a fall by improving the balance and gait of the user. OBJECTIVES: The objective of the review was to evaluate the effectiveness of foot and ankle devices for the prevention of falls and the improvement of balance and gait in adults with sensory perception loss. INCLUSION CRITERIA TYPES OF PARTICIPANTS: Participants were community-dwelling adults with bilateral pathological sensory perception loss...
December 2016: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/27585063/global-epidemiology-of-diabetic-foot-ulceration-a-systematic-review-and-meta-analysis-%C3%A2
#12
Pengzi Zhang, Jing Lu, Yali Jing, Sunyinyan Tang, Dalong Zhu, Yan Bi
Diabetic foot is a severe public health issue, yet rare studies investigated its global epidemiology. Here we performed a systematic review and meta-analysis through searching PubMed, EMBASE, ISI Web of science, and Cochrane database. We found that that global diabetic foot ulcer prevalence was 6.3% (95%CI: 5.4-7.3%), which was higher in males (4.5%, 95%CI: 3.7-5.2%) than in females (3.5%, 95%CI: 2.8-4.2%), and higher in type 2 diabetic patients (6.4%, 95%CI: 4.6-8.1%) than in type 1 diabetics (5.5%, 95%CI: 3...
March 2017: Annals of Medicine
https://www.readbyqxmd.com/read/27583022/skin-disorders-in-diabetes-mellitus-an-epidemiology-and-physiopathology-review
#13
REVIEW
Geisa Maria Campos de Macedo, Samanta Nunes, Tania Barreto
Skin disorders, usually neglected and frequently underdiagnosed among diabetic patients, are common complications and encounter a broad spectrum of disorders in both type 1 and type 2 diabetes mellitus (DM)-e.g. cutaneous infection, dry skin, pruritus. Skin disorders are highly associated with increased risk of important outcomes, such as skin lesions, ulcerations and diabetic foot, which can lead to major complications and revolve around multifactorial factors besides hyperglycemia and advanced glycation end products...
2016: Diabetology & Metabolic Syndrome
https://www.readbyqxmd.com/read/27574651/epidemiology-of-foot-burns-in-a-dutch-burn-centre
#14
Tülay Kılıç, Pieta Krijnen, Wim E Tuinebreijer, Roelf S Breederveld
BACKGROUND: Although the feet involve a small percentage of the total body surface area, they can have major effects in daily life, caused by prolonged bed rest, hospitalization and high risk of both early and late complications. The aim of this study was to define the aetiology, treatment and outcomes of foot burns, with special interest in paediatric patients, patients with diabetic disease and burns acquired at the workplace. METHODS: This is a retrospective cohort study of 82 patients who were admitted to one of the three burn centres in the Netherlands during the period 2004 to 2013...
2015: Burns and trauma
https://www.readbyqxmd.com/read/27556897/epidemiology-of-methicillin-resistant-staphylococcus-aureus-diabetic-foot-infections-in-a-large-academic-hospital-implications-for-antimicrobial-stewardship
#15
Kelly R Reveles, Bryson M Duhon, Robert J Moore, Elizabeth O Hand, Crystal K Howell
INTRODUCTION: Diabetic foot infections (DFIs) are the leading cause of non-traumatic lower extremity amputations in the United States. Antimicrobials active against methicillin-resistant Staphylococcus aureus (MRSA) are recommended in patients with associated risk factors; however, limited data exist to support these recommendations. Due to the changing epidemiology of MRSA, and the consequences of unnecessary antibiotic therapy, guidance regarding the necessity of empirical MRSA coverage in DFIs is needed...
2016: PloS One
https://www.readbyqxmd.com/read/27556759/what-role-does-function-play-in-deciding-on-limb-salvage-versus-amputation-in-patients-with-diabetes
#16
REVIEW
Dane K Wukich, Katherine M Raspovic
BACKGROUND: Patients with diabetic foot disease are at an increased risk for lower extremity amputation (LEA), premature mortality, and reduced health-related quality of life. In the setting of chronic infection, significant tissue loss, and/or an unstable deformity, limb salvage may not be possible, and major amputation is necessary. METHODS: The primary goal of this study was to review the literature with an emphasis on the functional aspects associated with successful limb salvage versus major LEA...
September 2016: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/27504557/major-lower-limb-amputations-experience-of-a-tertiary-care-hospital-in-sri-lanka
#17
D H B Ubayawansa, W Y M Abeysekera, M M A J Kumara
OBJECTIVE: To determine the epidemiology and conditions frequently seen in major lower extremity amputation. STUDY DESIGN: Observational study. PLACE AND DURATION OF STUDY: Teaching Hospital Karapitiya, Sri Lanka, from October 2013 to September 2014. METHODOLOGY: Major lower limb amputations were identified according to ICD-10 criteria. Data was retrospectively collected. Type of the amputation, indication for the amputation, gender and age of the patients, and mortality were noted...
July 2016: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/27449710/prevalence-and-comorbidities-of-double-diabetes
#18
S R Merger, W Kerner, M Stadler, A Zeyfang, P Jehle, M Müller-Korbsch, R W Holl
BACKGROUND: A growing number of people with type 1 diabetes (T1DM) are identified with features of metabolic syndrome (MS) known as "double diabetes", but epidemiologic data on the prevalence of MS in T1DM and its comorbidities are still lacking. Aim of this cross sectional study is to better estimate the prevalence of MS in T1DM, and to assess its association with comorbidities. METHODS: Data of 31,119 persons with autoimmune diabetes mellitus were analysed for signs of MS and presence of late complications...
September 2016: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/27445007/effects-of-foot-complications-in-patients-with-type-2-diabetes-mellitus-on-public-healthcare-an-analysis-based-on-the-korea-national-diabetes-program-cohort
#19
So Young Park, Sang Youl Rhee, Suk Chon, Kyu Jeung Ahn, Sung-Hoon Kim, Sei Hyun Baik, Yongsoo Park, Moon Suk Nam, Kwan Woo Lee, Jeong-Taek Woo, Ki Hong Chun, Young Seol Kim
AIM: Diabetes mellitus (DM) patients are susceptible to foot injury or foot diseases such as diabetic foot and peripheral arterial disease. Although these conditions are considered important, few studies have investigated them in detail. Therefore, we investigated the epidemiology of diabetic foot complications (DFC) with respect to the effects on the public healthcare system. METHODS: We evaluated the incidence, clinical characteristics, health service utilization frequency and medical expenses of DFC in type 2 DM patients in the Korea National Diabetes Program (KNDP), the largest multi-center, prospective cohort in Korea (n=4405)...
February 2017: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/27339028/susceptibility-patterns-of-staphylococcus-aureus-biofilms-in-diabetic-foot-infections
#20
Carla Mottola, Carina S Matias, João J Mendes, José Melo-Cristino, Luís Tavares, Patrícia Cavaco-Silva, Manuela Oliveira
BACKGROUND: Foot infections are a major cause of morbidity in people with diabetes and the most common cause of diabetes-related hospitalization and lower extremity amputation. Staphylococcus aureus is by far the most frequent species isolated from these infections. In particular, methicillin-resistant S. aureus (MRSA) has emerged as a major clinical and epidemiological problem in hospitals. MRSA strains have the ability to be resistant to most β-lactam antibiotics, but also to a wide range of other antimicrobials, making infections difficult to manage and very costly to treat...
June 23, 2016: BMC Microbiology
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