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https://www.readbyqxmd.com/read/29145720/phospholipase-d-and-its-essential-role-in-cancer
#1
Ju Hwan Cho, Joong-Soo Han
The role of Phospholipase D (PLD) in cancer development and management has been a major area of interest for researchers. The purpose of this mini-review is to explore PLD and its distinct role during chemotherapy including anti-apoptotic function. PLD is an enzyme that belongs to the phospholipase super family and is found in a broad range of organisms such as viruses, yeast, bacteria, animals, and plants. The function and activity of PLD are widely dependent on and regulated by neurotransmitters, hormones, small monomeric GTPases, and lipids...
November 16, 2017: Molecules and Cells
https://www.readbyqxmd.com/read/29145070/arsenic-forms-and-their-combinations-induce-differences-in-phenolic-accumulation-in-ulmus-laevis-pall
#2
Kinga Drzewiecka, Monika Gąsecka, Paweł Rutkowski, Zuzanna Magdziak, Piotr Goliński, Mirosław Mleczek
Total phenolics and the profile of phenolic acids and flavonoids were investigated in the roots and leaves of Ulmus laevis cultured on the medium with inorganic and organic arsenic - As(III), As(V) and DMA(V) at 0.06mM and their equimolar combinations. Further, the accumulation of salicylic acid (free and glucoside-bound) and lipid oxidation were assayed following a three-month long experiment. As treatment caused elevated production of phenolics, which was higher in photosynthetic tissue than in roots for all As forms and their combinations, and their overall content was correlated with the accumulation of organic As in roots and As(III) in leaves...
November 11, 2017: Journal of Plant Physiology
https://www.readbyqxmd.com/read/29143601/morphological-description-and-dna-barcoding-study-of-sand-rice-agriophyllum-squarrosum-chenopodiaceae-collected-in-kazakhstan
#3
Yuliya Genievskaya, Saule Abugalieva, Aibatsha Zhubanysheva, Yerlan Turuspekov
BACKGROUND: Sand rice (Agriophyllum squarrosum (L.) Moq.) is an annual shrub-like plant adapted to the mobile sand dunes in desert and semi-desert regions of Asia. It has a balanced nutrient composition with relatively high concentration of lipids and proteins, which results in its nutrition being similar to legumes. Sand rice's proteins contain the full range of essential amino acids. However, calories content is more similar to wheat. These features together with desert stress resistance make sand rice a potential food crop resilient to ongoing climate change...
November 14, 2017: BMC Plant Biology
https://www.readbyqxmd.com/read/29143394/bactericera-cockerelli-vitellogenin-6-like-a-vitellogenin-without-a-direct-reproductive-function
#4
F Ibanez, X Tang, C Tamborindeguy
Vitellogenin-like proteins are members of the large lipid transfer proteins, a family of proteins involved in reproduction, lipid circulation and immune defences. In this study, we identified a new Bactericera cockerelli vitellogenin-like (Vg-like) transcript, and named it BcVg6-like based on its similarity to Acyrthosiphon pisum Vg6. In silico analyses predicted different conserved domains in BcVg6-like compared with the conventional Ba. cockerelli vitellogenin, BcVg1-like, previously described by our research group...
November 16, 2017: Insect Molecular Biology
https://www.readbyqxmd.com/read/29142430/topical-delivery-of-withania-somnifera-crude-extracts-in-niosomes-and-solid-lipid-nanoparticles
#5
Tawona N Chinembiri, Minja Gerber, Lissinda H du Plessis, Jan L du Preez, Josias H Hamman, Jeanetta du Plessis
Background: Withania somnifera is a medicinal plant native to India and is known to have anticancer properties. It has been investigated for its anti-melanoma properties, and since melanoma presents on the skin, it is prudent to probe the use of W. somnifera in topical formulations. To enhance topical drug delivery and to allow for controlled release, the use of niosomes and solid lipid nanoparticles (SLNs) as delivery vesicles were explored. Objective: The objective of this study is to determine the stability and topical delivery of W...
October 2017: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/29142389/bioactive-constituents-radical-scavenging-and-antibacterial-properties-of-the-leaves-and-stem-essential-oils-from-peperomia-pellucida-l-kunth
#6
Sunday O Okoh, Benson C Iweriebor, Omobola O Okoh, Anthony I Okoh
Background: Peperomia pellucida is an annual herbaceous ethnomedicinal plant used in the treatment of a variety of communicable and noncommunicable diseases in the Amazon region. Objective: The study aimed at profiling the bioactive constituents of the leaves and stem essential oils (LEO and SEO) of P. pellucida, their in vitro antibacterial and radical scavenging properties as probable lead constituents in the management of oxidative stress and infectious diseases...
October 2017: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/29141586/profiling-membrane-glycerolipids-during-%C3%AE-ray-induced-membrane-injury
#7
Guowei Zheng, Weiqi Li
BACKGROUND: γ-rays are high-energy radiation that cause a range of random injuries to plant cells. Most studies on this issue have focused on γ-ray-induced nucleotide damage and the production of reactive oxygen species in cells, so little is known about the glycerolipid metabolism during γ-rays induced membrane injury. Using an ESI-MS/MS-based lipidomic method, we analysed the lipidome changes in wild-type and phospholipase D (PLD)δ- and α1-deficient Arabidopsis after γ-ray treatment...
November 15, 2017: BMC Plant Biology
https://www.readbyqxmd.com/read/29140451/lipids-in-membrane-dynamics-during-autophagy-in-plants
#8
Rodrigo Enrique Gomez, Jérôme Joubès, Nicolas Valentin, Henri Batoko, Béatrice Satiat-Jeunemaître, Amélie Bernard
Autophagy is a critical pathway for plant adaptation to stress. Macroautophagy relies on the biogenesis of a specialized membrane named the phagophore that maturates into a double membrane vesicle. Proteins and lipids act synergistically to promote membrane structure and functions, yet research on autophagy has mostly focused on autophagy-related proteins while knowledge of supporting lipids in the formation of autophagic membranes remains scarce. This review expands on studies in plants with examples from other organisms to present and discuss our current understanding of lipids in membrane dynamics associated with the autophagy pathway in plants...
November 13, 2017: Journal of Experimental Botany
https://www.readbyqxmd.com/read/29139349/leucobacter-triazinivorans-sp-nov-a-s-triazine-herbicide-prometryn-degrading-bacterium-isolated-from-sludge
#9
Le-Ni Sun, Dan-Dan Pan, Xiang-Wei Wu, En-Dong Yang, Ri-Mao Hua, Qing X Li
A Gram-stain-positive, rod-shaped, non-motile bacterial strain, designated JW-1(T), was isolated from activated sludge collected from the outlet of an aeration tank in a prometryn-manufacturing plant, located in Binzhou City, Shandong province, PR China. Phylogenetic analysis, based on 16S rRNA gene sequences, indicated that strain JW-1(T) belongs to the genus Leucobacter and its closest neighbours are 'Leucobacter kyeonggiensis' F3-P9 (98.95 % similarity), Leucobacter celer subsp. astrifaciens CBX151(T) (98...
November 15, 2017: International Journal of Systematic and Evolutionary Microbiology
https://www.readbyqxmd.com/read/29138829/resveratrol-ameliorates-inflammatory-damage-and-protects-against-osteoarthritis-in-a-rat-model-of-osteoarthritis
#10
Yulong Wei, Jie Jia, Xin Jin, Wei Tong, Hongtao Tian
Resveratrol is a non‑flavonoid polyphenol compound with a stilbene structure. As a type of phytoalexin produced under stress in plants, it improves the plant's resistance against pathogens and environment deterioration, and performs important functions beneficial to human health, such as anti‑cancer, anti‑oxidation, regulating blood lipid levels and prolonging life span. The effects of resveratrol were examined in a rat model of osteoarthritis (OA) and observed to ameliorate inflammatory damage and protect against OA...
November 13, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29131851/gdsl-lipases-modulate-immunity-through-lipid-homeostasis-in-rice
#11
Mingjun Gao, Xin Yin, Weibing Yang, Sin Man Lam, Xiaohong Tong, Jiyun Liu, Xin Wang, Qun Li, Guanghou Shui, Zuhua He
Lipids and lipid metabolites play important roles in plant-microbe interactions. Despite the extensive studies of lipases in lipid homeostasis and seed oil biosynthesis, the involvement of lipases in plant immunity remains largely unknown. In particular, GDSL esterases/lipases, characterized by the conserved GDSL motif, are a subfamily of lipolytic enzymes with broad substrate specificity. Here, we functionally identified two GDSL lipases, OsGLIP1 and OsGLIP2, in rice immune responses. Expression of OsGLIP1 and OsGLIP2 was suppressed by pathogen infection and salicylic acid (SA) treatment...
November 13, 2017: PLoS Pathogens
https://www.readbyqxmd.com/read/29129239/an-iso-%C3%AE-acid-rich-extract-from-hops-humulus-lupulus-attenuates-acute-alcohol-induced-liver-steatosis-in-mice
#12
Marianne Hege, Finn Jung, Cathrin Sellmann, Chengjun Jin, Doreen Ziegenhardt, Claus Hellerbrand, Ina Bergheim
OBJECTIVE: Results of in vitro and in vivo studies suggest that consumption of beer is less harmful for the liver than consumption of spirits. It also has been suggested that secondary plant compounds derived from hops such as xanthohumol or iso-α-acids may have beneficial effects on the development of liver diseases of various etiologies. The aim of this study was to determine whether iso-α-acids consumed in doses achieved by "normal" beer consumption have beneficial effects on health...
January 2018: Nutrition
https://www.readbyqxmd.com/read/29128781/photosynthesis-impairments-and-excitation-energy-dissipation-on-wheat-plants-supplied-with-silicon-and-infected-with-pyricularia-oryzae
#13
Carlos Eduardo Aucique-Pérez, Paulo Eduardo de Menezes Silva, Wiler Ribas Moreira, Fábio Murilo DaMatta, Fabrício Ávila Rodrigues
Considering the effect of silicon (Si) in reducing the blast symptoms on wheat in a scenario where the losses in the photosynthetic capacity of the infected plants is lowered, this study investigated the ability of using the incident light, the chloroplastidic pigments (chlorophylls and carotenoids) alterations and the possible role of carotenoids on the process of light dissipation on wheat plants non-supplied (-Si) or supplied (+Si) with Si and inoculated or not with Pyricularia oryzae. For + Si plants, blast severity was reduced compared to -Si plants...
October 26, 2017: Plant Physiology and Biochemistry: PPB
https://www.readbyqxmd.com/read/29128767/biochar-alleviates-phytotoxicity-in-ficus-elastica-grown-in-zn-contaminated-soil
#14
Abhay Kumar, Ludmila Tsechansky, Beni Lew, Eran Raveh, Omer Frenkel, Ellen R Graber
Zinc (Zn) immobilization by two distinct biochars in soil, together with concomitant alleviation of phytotoxic responses in Ficus elastica Roxb. ex Hornem., were examined. Rooted cuttings of F. elastica were grown in 880mgkg(-1) Zn-spiked sandy soil amended with grain husk (GH) or cattle manure (CM) biochar at 0, 10, 30 and 50gkg(-1) soil for a period of 6months. Addition of both GH and CM biochars had significant positive impacts on physiological parameters such as plant growth, leaf relative water content, photosynthetic pigments and leaf gas exchange characteristics...
November 9, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29127883/metabolic-engineering-of-yeast-for-lignocellulosic-biofuel-production
#15
REVIEW
Yong-Su Jin, Jamie Hd Cate
Production of biofuels from lignocellulosic biomass remains an unsolved challenge in industrial biotechnology. Efforts to use yeast for conversion face the question of which host organism to use, counterbalancing the ease of genetic manipulation with the promise of robust industrial phenotypes. Saccharomyces cerevisiae remains the premier host for metabolic engineering of biofuel pathways, due to its many genetic, systems and synthetic biology tools. Numerous engineering strategies for expanding substrate ranges and diversifying products of S...
November 8, 2017: Current Opinion in Chemical Biology
https://www.readbyqxmd.com/read/29127819/morphological-response-of-a-cactus-to-cement-dust-pollution
#16
Juan Manuel E Drack, Diego P Vázquez
Cement dust from cement plants around the world has multiple negative effects on organisms and their environment. Cement's effects come from its strongly alkaline nature and high content of heavy metals. Previous studies on plants have documented that cement dust deposition can influence plant vegetative growth, the lipid and ionic composition of tissues, and foliar temperature. Here we evaluate the effects of cement dust coming from a plant in western Argentina on the morphology of the cactus Tephrocactus aoracanthus...
November 8, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/29125459/pseudogracilibacillus-endophyticus-sp-nov-a-moderately-thermophilic-and-halophilic-species-isolated-from-plant-root
#17
Jisun Park, Min-Kyeong Kim, Bo-Ram Yun, Ji-Hye Han, Seung Bum Kim
A Gram-stain-positive strain, designated DT7-02(T), was isolated from the surface-sterilized root of Oenotherabiennis (evening primrose) and subjected to taxonomic characterization. Cells of DT7-02(T) were slender rod-shaped, motile by means of flagella, and oxidase- and catalase-positive. The colonies were circular, pinkish-yellow, opaque, glistering and 1-2 mm in diameter. The strain was moderately thermophilic and halophilic, as growth occurred at 20-44 °C (optimum 40 °C), pH 7-10 (optimum pH 8-9) and in the presence of 0-8 % of NaCl (optimum 4 %) in tryptic soy broth...
November 10, 2017: International Journal of Systematic and Evolutionary Microbiology
https://www.readbyqxmd.com/read/29125288/uptake-translocation-and-biotransformation-of-organophosphorus-esters-in-wheat-triticum-aestivum-l
#18
Weining Wan, Honglin Huang, Jitao Lv, Ruixia Han, Shuzhen Zhang
The uptake, translocation and biotransformation of organophosphate esters (OPEs) by wheat (Triticum aestivum L.) were investigated by a hydroponic experiment. The results demonstrated that OPEs with higher hydrophobicity were more easily taken up by roots, and OPEs with lower hydrophobicity were more liable to be translocated acropetally. A total of 43 metabolites including dealkylated, oxidatively dechlorinated, hydroxylated, methoxylated, and glutathione- and glucuronide- conjugated products were detected derived from eight OPEs, with di-esters formed by direct dealkylation from the parent tri-esters as the major products, followed with hydroxylated tri-esters...
November 10, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/29124702/impact-of-uv-radiation-on-genome-stability-and-human-health
#19
Sujit Roy
Gradual depletion of the atmospheric ozone layer during the past few years has increased the incidence of solar UV radiation specifically the UV-C on earth's surface is one of the major environmental concerns because of the harmful effects of this radiation in all forms of life. The solar UV radiation including the harmful wavelength range of UV-B (280-320 nm) represents a significant climatic stress for both animals and plants, causing damage to the fundamental biomolecules such as DNA, proteins and lipids, thus activating genotoxic stress and induces genome instability...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/29121271/genome-wide-identification-of-arabidopsis-lbd29-target-genes-reveals-the-molecular-events-behind-auxin-induced-cell-reprograming-during-callus-formation
#20
Chongyi Xu, Huifen Cao, Enjun Xu, Shiqi Zhang, Yuxin Hu
Auxin-induced callus formation represents an important cell reprograming process during in vitro regeneration of plants, in which the pericycle or pericycle-like cells within plant organs are reprogramed into the pluripotent cell mass termed callus that is generally required for subsequent regeneration of root or shoot. However, the molecular events behind cell reprograming during auxin-induced callus formation are largely elusive. We previously identified that auxin-induced LBD transcription factors act as the master regulators to trigger auxin-induced callus formation...
November 7, 2017: Plant & Cell Physiology
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