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https://www.readbyqxmd.com/read/28333789/nursing-informatics-competency-assessment-for-the-nurse-leader-the-delphi-study
#1
Sarah Collins, Po-Yin Yen, Andrew Phillips, Mary K Kennedy
OBJECTIVE: The aim of this study was to identify nursing informatics competencies perceived as relevant and required by nurse leaders. BACKGROUND: To participate as a full partner in healthcare leadership among rapidly advancing health information technologies (HITs), nurse leaders must attain knowledge of informatics competencies related to their clinical leadership roles and responsibilities. Despite this increased need to engage in HIT-related decision making, a gap remains in validated informatics competencies specific to the needs of nurse leaders...
April 2017: Journal of Nursing Administration
https://www.readbyqxmd.com/read/28322513/site-of-metabolism-prediction-based-on-ab-initio-derived-atom-representations
#2
Arndt R Finkelmann, Andreas H Göller, Gisbert Schneider
Machine learning models for site of metabolism (SoM) prediction offer the ability to identify metabolic soft spots in low molecular weight drug molecules at low computational cost and enable data-based reactivity prediction. SoM prediction is an atom classification problem. Successful construction of machine learning models requires atom representations that capture the reactivity-determining features of a potential reaction site. We have developed a descriptor scheme that characterizes an atom's steric and electronic environment and its relative location in the molecular structure...
March 21, 2017: ChemMedChem
https://www.readbyqxmd.com/read/28291725/in-situ-operating-room-based-simulation-a-review
#3
Lily Owei, Christopher J Neylan, Raghavendra Rao, Robert C Caskey, Jon B Morris, Richard Sensenig, Ari D Brooks, Daniel T Dempsey, Noel N Williams, Joshua H Atkins, Dimitry Y Baranov, Kristoffel R Dumon
OBJECTIVE: To systematically review the literature surrounding operating room-based in situ training in surgery. METHODS: A systematic review was conducted of MEDLINE. The review was conducted based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) methodology, and employed the Population, Intervention, Comparator, Outcome (PICO) structure to define inclusion/exclusion criteria. The Kirkpatrick model was used to further classify the outcome of in situ training when possible...
March 10, 2017: Journal of Surgical Education
https://www.readbyqxmd.com/read/28255159/high-intensity-aerobic-exercise-training-improves-chronic-intermittent-hypoxia-induced-insulin-resistance-without-basal-autophagy-modulation
#4
Marion Pauly, Allan Assense, Aurélie Rondon, Amandine Thomas, Hervé Dubouchaud, Damien Freyssenet, Henri Benoit, Josiane Castells, Patrice Flore
Chronic intermittent hypoxia (IH) associated with obstructive sleep apnea (OSA) is a major risk factor for cardiovascular and metabolic diseases (insulin resistance: IR). Autophagy is involved in the pathophysiology of IR and high intensity training (HIT) has recently emerged as a potential therapy. We aimed to confirm IH-induced IR in a tissue-dependent way and to explore the preventive effect of HIT on IR-induced by IH. Thirty Swiss 129 male mice were randomly assigned to Normoxia (N), Intermittent Hypoxia (IH: 21-5% FiO2, 30 s cycle, 8 h/day) or IH associated with high intensity training (IH HIT)...
March 3, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28251664/preservation-of-skeletal-muscle-mitochondrial-content-in-older-adults-relationship-between-mitochondria-fibre-type-and-high-intensity-exercise-training
#5
Victoria L Wyckelsma, Itamar Levinger, Michael J McKenna, Luke E Formosa, Michael T Ryan, Aaron C Petersen, Mitchell J Anderson, Robyn M Murphy
KEYPOINTS SUMMARY: Ageing is associated with an upregulation of mitochondrial dynamics proteins, mitofusin 2 (Mfn2) and mitochondrial dynamics protein 49 (MiD49) in human skeletal muscle, the increased abundance of Mfn2 is exclusive to Type II muscle fibres. These changes occur despite a similar content of mitochondria, as measured by COXIV, NDUFA9 and complexes in their native states (Blue Native PAGE). Following 12 weeks of High-Intensity Training (HIT), older adults exhibit a robust increase in mitochondria content...
March 1, 2017: Journal of Physiology
https://www.readbyqxmd.com/read/28221002/computational-biology-and-chemistry-in-mti-emphasis-on-the-prediction-of-some-admet-properties
#6
REVIEW
Maria A Miteva, Bruno O Villoutreix
Our research and teaching group called MTi (Molécules Thérapeutiques in silico) has developed numerous applications available online, thanks to the RPBS platform (Ressource Parisienne en Bioinformatique Structurale), in the field of chemoinformatics, structural bioinformatics and drug design. Since its opening in 2009, over 200 articles/reviews have been reported and involve virtual screening studies, prediction of druggability, analysis of protein-protein interaction inhibitors, development of databases, data mining and knowledge discovery, as well as combined in silico-in vitro work to search for new hits and chemical probes acting on original targets in several therapeutic areas...
February 21, 2017: Molecular Informatics
https://www.readbyqxmd.com/read/28219086/first-report-of-awake-craniotomy-of-a-famous-musician-suprasellar-tumor-surgery-of-pianist-clara-haskil-in-1942
#7
Elena Romana Gasenzer, Ayhan Kanat, Edmund A M Neugebauer
Clara Haskil (January 7, 1895-December 7, 1960) was one of the most famous female pianists of the 20th century. In her life and work she set new standards in piano playing. However, her career was beset by poor health and the adversities of two world wars. In her lifetime Haskil had three major disorders: juvenile scoliosis requiring treatment in her adolescence, a tumor of the sellar region requiring surgery at age 47 years, and a traumatic brain injury causing her death at the age of 65. Her medical history illustrates the development of surgical methods and rehabilitation in medicine before and after World War II...
February 20, 2017: Journal of Neurological Surgery. Part A, Central European Neurosurgery
https://www.readbyqxmd.com/read/28210335/training-level-does-not-affect-auditory-perception-of-the-magnitude-of-ball-spin-in-table-tennis
#8
Daniel P R Santos, Roberto N Barbosa, Luiz H P Vieira, Paulo R P Santiago, Alessandro M Zagatto, Matheus M Gomes
Identifying the trajectory and spin of the ball with speed and accuracy is critical for good performance in table tennis. The aim of this study was to analyze the ability of table tennis players presenting different levels of training/experience to identify the magnitude of the ball spin from the sound produced when the racket hit the ball. Four types of "forehand" contact sounds were collected in the laboratory, defined as: Fast Spin (spinning ball forward at 140 r/s); Medium Spin (105 r/s); Slow Spin (84 r/s); and Flat Hit (less than 60 r/s)...
January 1, 2017: Journal of Human Kinetics
https://www.readbyqxmd.com/read/28198783/effect-of-moderate-versus-high-intensity-interval-exercise-training-on-heart-rate-variability-parameters-in-inactive-latin-american-adults-a-randomised-clinical-trial
#9
Robinson Ramírez-Vélez, Alejandra Tordecilla-Sanders, Luis Andrés Téllez-T, Diana Camelo-Prieto, Paula Andrea Hernández-Quiñonez, Jorge Enrique Correa-Bautista, Antonio Garcia-Hermoso, Rodrigo Ramírez-Campillo, Mikel Izquierdo
We investigated the effect of moderate versus high-intensity interval exercise training on the HRV indices in physically inactive adults. Twenty inactive adults were randomly allocated to receive either moderate intensity training (MCT group) or high-intensity interval training (HIT group). The MCT group performed aerobic training at an intensity of 55-75%, which consisted of walking on a treadmill at 60-80% of the maximum heart rate (HRmax) until the expenditure of 300 kcal. The HIT group ran on a treadmill for 4 minutes at 85-95% peak HRmax and had a recovery of 4 minutes at 65% peak HRmax until the expenditure of 300 kcal...
February 1, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28182523/monitoring-hitting-load-in-tennis-using-inertial-sensors-and-machine-learning
#10
David Whiteside, Olivia Cant, Molly Connolly, Machar Reid
PURPOSE: Quantifying external workload is fundamental to training prescription in sport. In tennis, global positioning data are imprecise and fail to capture hitting loads. The current gold standard (manual notation) is time intensive and often not possible given players' heavy travel schedules. The aim of this study was to develop an automated stroke classification system to help quantify hitting load in tennis. METHODS: 18 athletes wore an inertial measurement unit (IMU) on their wrist during 66 video-recorded training sessions...
February 9, 2017: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/28161874/mindfulness-and-pharmacological-prophylaxis-after-withdrawal-from-medication-overuse-in-patients-with-chronic-migraine-an-effectiveness-trial-with-a-one-year-follow-up
#11
Licia Grazzi, Emanuela Sansone, Alberto Raggi, Domenico D'Amico, Andrea De Giorgio, Matilde Leonardi, Laura De Torres, Francisco Salgado-García, Frank Andrasik
BACKGROUND: Chronic Migraine (CM) is a disabling condition, worsened when associated with Medication Overuse (MO). Mindfulness is an emerging technique, effective in different pain conditions, but it has yet to be explored for CM-MO. We report the results of a study assessing a one-year course of patients' status, with the hypothesis that the effectiveness of a mindfulness-based approach would be similar to that of conventional prophylactic treatments. METHODS: Patients with CM-MO (code 1...
December 2017: Journal of Headache and Pain
https://www.readbyqxmd.com/read/28154947/autonomic-cardiovascular-modulation-in-masters-and-young-cyclists-following-high-intensity-interval-training
#12
Nattai R Borges, Peter R Reaburn, Thomas M Doering, Christos K Argus, Matthew W Driller
PURPOSE: This study aimed at examining the autonomic cardiovascular modulation in well-trained masters and young cyclists following high-intensity interval training (HIT). METHODS: Nine masters (age 55.6 ± 5.0 years) and eight young cyclists (age 25.9 ± 3.0 years) completed a HIT protocol of 6 x 30 sec at 175% of peak power output, with 4.5-min' rest between efforts. Immediately following HIT, heart rate and R-R intervals were monitored for 30-min during passive supine recovery...
February 2, 2017: Clinical Autonomic Research: Official Journal of the Clinical Autonomic Research Society
https://www.readbyqxmd.com/read/28146032/different-training-loads-partially-influence-physiological-responses-to-preparation-period-in-basketball
#13
Davide Ferioli, Andrea Bosio, Antonio La Torre, Domenico Carlomagno, Darragh R Connolly, Ermanno Rampinini
The aim of this study was to compare perceived TL (sRPE-TL), training volume (TV) and the changes in physical fitness between professional (n=14) and semi-professional (n=18) basketball players during the preparation period. Furthermore, relationships between sRPE-TL and TV with changes in physical fitness level were investigated. The players performed the Yo-Yo Intermittent Recovery Test (Yo-Yo IR1) before and after the preparation period. In addition, physiological responses to a standardized 6-min continuous running test (Mognoni's test) and to a standardized 5-min high-intensity intermittent running test (HIT) were measured...
January 30, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28136698/breaking-the-cycles-of-poverty-strategies-achievements-and-lessons-learned-in-los-cuatro-santos-nicaragua-1990-2014
#14
Elmer Zelaya Blandón, Carina Källestål, Rodolfo Peña, Wilton Perez, Staffan Berglund, Mariela Contreras, Lars-Åke Persson
BACKGROUND: In a post-war frontier area in north-western Nicaragua that was severely hit by Hurricane Mitch in 1998, local stakeholders embarked on and facilitated multi-dimensional development initiatives to break the cycles of poverty. OBJECTIVE: The aim of this paper is to describe the process of priority-setting, and the strategies, guiding principles, activities, achievements, and lessons learned in these local development efforts from 1990 to 2014 in the Cuatro Santos area, Nicaragua...
2017: Global Health Action
https://www.readbyqxmd.com/read/28136131/is-marathon-running-toxic-an-observational-study-of-cardiovascular-disease-prevalence-and-longevity-in-54-male-marathon-runners
#15
Benjamin Rosin
OBJECTIVES: Recent literature suggests reduced benefits associated with high intensity (HIT) and or sustained intensity exercise training (SIT). While important, they tend to contrast with other studies of HIT and SIT and may not be representative of all individuals wishing to participate in activities such as marathon running. The purpose of this observational report is to describe a 45-year history of 54 long distance runners, their incidence of death from cardiovascular disease and their ages at death compared to the normal population...
February 8, 2017: Physician and Sportsmedicine
https://www.readbyqxmd.com/read/28126605/cognitive-engineering-and-health-informatics-applications-and-intersections
#16
A Zachary Hettinger, Emilie Roth, Ann M Bisantz
Cognitive engineering is an applied field with roots in both cognitive science and engineering that has been used to support design of information displays, decision support, human-automation interaction, and training in numerous high risk domains ranging from nuclear power plant control to transportation and defense systems. Cognitive engineering provides a set of structured, analytic methods for data collection and analysis that intersect with and complement methods of Cognitive Informatics. These methods support discovery of aspects of the work that make performance challenging, as well as the knowledge, skills, and strategies that experts use to meet those challenges...
January 23, 2017: Journal of Biomedical Informatics
https://www.readbyqxmd.com/read/28125990/an-assessment-of-staffing-needs-at-a-hiv-clinic-in-a-western-kenya-using-the-who-workload-indicators-of-staffing-need-wisn-2011
#17
B Burmen, N Owuor, P Mitei
BACKGROUND: An optimal number of health workers, who are appropriately allocated across different occupations and geographical regions, are required to ensure population coverage of health interventions. Health worker shortages in HIV care provision are highest in areas that are worst hit by the HIV epidemic. Kenya is listed among countries that experience health worker shortages (<2.5 health workers per 1000 population) and have a high HIV burden (HIV prevalence 5.6 with 15.2% in Nyanza province)...
January 26, 2017: Human Resources for Health
https://www.readbyqxmd.com/read/28122657/challenges-and-opportunities-to-engaging-emergency-medical-service-providers-in-substance-use-research-a-qualitative-study
#18
Allysha C Maragh-Bass, Julie C Fields, Junette McWilliams, Amy R Knowlton
Introduction Research suggests Emergency Medical Services (EMS) over-use in urban cities is partly due to substance users with limited access to medical/social services. Recent efforts to deliver brief, motivational messages to encourage these individuals to enter treatment have not considered EMS providers. Problem Little research has been done with EMS providers who serve substance-using patients. The EMS providers were interviewed about participating in a pilot program where they would be trained to screen their patients for substance abuse and encourage them to enter drug treatment...
January 26, 2017: Prehospital and Disaster Medicine
https://www.readbyqxmd.com/read/28121800/effects-of-hit-on-physiological-and-hormonal-adaptions-in-well-trained-cyclists
#19
Øystein Sylta, Espen Tønnessen, Øyvind Sandbakk, Daniel Hammarström, Jørgen Danielsen, Knut Skovereng, Bent R Rønnestad, Stephen Seiler
PURPOSE: Investigate development of specific performance adaptions and hormonal responses every 4 week during a 12-week HIT period in groups with different interval-training prescriptions. METHODS: Sixty-three well-trained cyclists performing a 12-week intervention consisting of 2-3 HIT sessionsweek in addition to ad libitum low intensity training. Groups were matched for total training load, but increasing HIT (INC) group (n=23) performed interval-sessions as 4x16 min in week 1-4, 4x8 min in week 5-8 and 4x4 min in week 9-12...
January 23, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28116879/physical-activity-in-the-prevention-and-management-of-bladder-cancer
#20
Roy J Shephard
INTRODUCTION: The aim was to examine the role of physical activity in reducing the risk of bladder cancer, and in managing established disease. EVIDENCE ACQUISITION: A systematic search of Ovid/Medline from 1996 to June 2016 coupled the term urinary bladder neoplasms (25,061 hits) with markers of physical activity (exercise, physical activity, physical education/training, athletes, and physical fitness, a total of 246,683 unique entries). Of 42 titles identified, 18 relevant abstracts were supplemented by reviewing reference lists and personal files to yield 21 articles on prevention of bladder cancer, and 8 on physical activity in disease management...
January 23, 2017: Journal of Sports Medicine and Physical Fitness
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