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https://www.readbyqxmd.com/read/28097470/hepatic-echinococcosis
#1
Andreas Lorenz, Christian Andreas Nebiker
No abstract text is available yet for this article.
January 17, 2017: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/28096605/molecular-and-epidemiological-updates-on-cystic-echinococcosis-infecting-water-buffaloes-from-egypt
#2
Ibrahim Abbas
AIM: Cystic echinococcosis (CE) represents a serious parasitic disease at both animal and public health levels. The majority of reports negated the CE infection in buffaloes from Egypt; however, one study illustrated their infection with G6 genotype (camel strain). The present work contributed to update the epidemiological and molecular knowledge about CE infecting this economically important animal for better understanding of its role in maintaining the Echinococcus life cycle. MATERIALS AND METHODS: A total of 120 slaughtered water buffaloes at Mansoura abattoir, Dakahlia province, Egypt, were inspected for the existence of hydatid cysts...
December 2016: Veterinary World
https://www.readbyqxmd.com/read/28095662/factors-associated-with-echinococcosis-induced-perioperative-anaphylactic-shock
#3
Jianrong Ye, Qin Zhang, Yan Xuan, Siyu Chen, Long Ma, Yongqiang Zhang, Hong Zheng
This retrospective case-control study explored the factors associated with anaphylactic shock during surgery for cystic echinococcosis (CE) at the First Affiliated Hospital of Xinjiang Medical University between October 2008 and September 2013. Patients who suffered from anaphylactic shock (n=16) were age-matched 3:1 to patients who did not (n=43). Multivariate analysis suggested that IL-4 levels (odds ratio=1.096; 95% confidence interval=1.015-1.185; P=0.02) and cyst size (odds ratio=3.028, 95% confidence interval=1...
December 2016: Korean Journal of Parasitology
https://www.readbyqxmd.com/read/28095661/molecular-cloning-and-characterization-of-a-p38-like-mitogen-activated-protein-kinase-from-echinococcus-granulosus
#4
Guodong Lü, Jing Li, Chuanshan Zhang, Liang Li, Xiaojuan Bi, Chaowang Li, Jinliang Fan, Xiaomei Lu, Dominique A Vuitton, Hao Wen, Renyong Lin
Cystic echinococcosis (CE) treatment urgently requires a novel drug. The p38 mitogen-activated protein kinases (MAPKs) are a family of Ser/Thr protein kinases, but still have to be characterized in Echinococcus granulosus. We identified a 1,107 bp cDNA encoding a 368 amino acid MAPK protein (Egp38) in E. granulosus. Egp38 exhibits 2 distinguishing features of p38-like kinases: a highly conserved T-X-Y motif and an activation loop segment. Structural homology modeling indicated a conserved structure among Egp38, EmMPK2, and H...
December 2016: Korean Journal of Parasitology
https://www.readbyqxmd.com/read/28088247/first-molecular-identification-of-echinococcus-vogeli-and-echinococcus-granulosus-sensu-stricto-g1-revealed-in-feces-of-domestic-dogs-canis-familiaris-from-acre-brazil
#5
Leandro Batista das Neves, Paulo Eduardo Ferlini Teixeira, Sidnei Silva, Fernanda Bittencourt de Oliveira, Daniel Daipert Garcia, Fernanda Barbosa de Almeida, Rosângela Rodrigues-Silva, José Roberto Machado-Silva
BACKGROUND: Echinococcus granulosus (sensu lato) (s.l.) and Echinococcus vogeli are causative agents of chronic zoonotic diseases such as cystic and polycystic echinococcosis, respectively. In Brazil, polycystic echinococcosis has a restricted geographical distribution in the North Region, while cystic echinococcosis is observed in the South Region. Domestic dogs (Canis familiaris) fed with raw viscera represent a risk factor for E. granulosus (s.l.) infection in the South Region. Although this practice is frequent, it remains unclear whether domestic dogs are infected with E...
January 14, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28086841/good-outcome-following-liver-transplantation-using-pericardial-peritoneum-window-for-hepato-atrial-anastomosis-to-overcome-advanced-hepatic-alveolar-echinococcosis-and-secondary-budd-chiari-syndrome-a-case-report
#6
Konrad Kobryń, Rafał Paluszkiewicz, Krzysztof Dudek, Urszula Ołdakowska-Jedynak, Michał Korba, Joanna Raszeja-Wyszomirska, Piotr Remiszewski, Michał Grąt, Piotr Milkiewicz, Waldemar Patkowski, Marek Krawczyk
BACKGROUND: This report presents a case of a 57- year old female with advanced Hepatic Alveolar Echinococcosis causing a secondary Budd-Chiari Syndrome due to infiltration of the suprahepatic inferior vena cava treated successfully by liver transplantation. CASE PRESENTATION: A temporary veno-venous bypass was introduced, but a typical end to end cavo-caval anastomosis wasn't possible in this case. In order to access a disease free part of the inferior vena cava, an oval window of the diaphragm was excised, providing communication between the peritoneum and pericardium...
January 13, 2017: BMC Surgery
https://www.readbyqxmd.com/read/28077161/mathematical-modelling-of-echinococcus-multilocularis-abundance-in-foxes-in-zurich-switzerland
#7
Belen Otero-Abad, Simon R Rüegg, Daniel Hegglin, Peter Deplazes, Paul R Torgerson
BACKGROUND: In Europe, the red fox (Vulpes vulpes) is the main definitive host of Echinococcus multilocularis, the aetiological agent of a severe disease in humans called alveolar echinococcosis. The distribution of this zoonotic parasite among the fox population is remarkably aggregated with few heavily infected animals harbouring much of the parasite burdens and being responsible for most of the environmental parasitic egg contamination. Important research questions explored were: (i) spatial differences in parasite infection pressure related to the level of urbanization; (ii) temporal differences in parasite infection pressure in relation to time of the year; (iii) is herd immunity or an age-dependent infection pressure responsible for the observed parasite abundance; (iv) assuming E...
January 11, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28070013/epidemiology-of-echinococcosis-among-schoolchildren-in-golog-tibetan-autonomous-prefecture-qinghai-china
#8
Huixia Cai, Yayi Guan, Xiao Ma, Liying Wang, Hu Wang, Guoming Su, Xuefei Zhang, Xiumin Han, Junying Ma, Yu Fang Liu, Jun Li, Jingxiao Zhang, Yongshun Wang, Wei Wang, Rui Du, Wen Lei, Weiping Wu
Echinococcosis is a serious zoonotic parasitic disease that is highly endemic in Qinghai Province. The present study aimed to investigate the prevalence of echinococcosis among schoolchildren in Golog Tibetan Autonomous Prefecture to improve early diagnosis and treatment of patients and to provide information for echinococcosis prevention and control. A total of 11,260 schoolchildren from five counties (Maqin, Gander, Dari, Jiuzhi, and Banma) in Golog Tibetan Autonomous Prefecture, Qinghai Province, were screened for echinococcosis...
January 9, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28070011/management-of-advanced-hepatic-alveolar-echinococcosis-report-of-42-cases
#9
Bo Qu, Long Guo, Guannan Sheng, Fei Yu, Guannan Chen, Yupeng Wang, Yuan Shi, Hanxiang Zhan, Yi Yang, Xiaoyan Du
Radical resection is the first choice for hepatic alveolar echinococcosis (HAE). However, many patients with advanced HAE have no chance to be treated with curative resection owing to the long clinical latency. This study aimed to evaluate the necessity of aggressive operations, like palliative resection and orthotopic liver transplantation (OLT), in the management of advanced HAE. A retrospective study analyzed 42 patients with advanced HAE treated with palliative resection (N = 15), palliative nonresective procedures (N = 13), OLT (N = 3), or albendazole therapy alone (N = 11)...
January 9, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28070008/expert-reliability-for-the-world-health-organization-standardized-ultrasound-classification-of-cystic-echinococcosis
#10
Nadia Solomon, Paul J Fields, Francesca Tamarozzi, Enrico Brunetti, Calum N L Macpherson
Cystic echinococcosis (CE), a parasitic zoonosis, results in cyst formation in the viscera. Cyst morphology depends on developmental stage. In 2003, the World Health Organization (WHO) published a standardized ultrasound (US) classification for CE, for use among experts as a standard of comparison. This study examined the reliability of this classification. Eleven international CE and US experts completed an assessment of eight WHO classification images and 88 test images representing cyst stages. Inter- and intraobserver reliability and observer performance were assessed using Fleiss' and Cohen's kappa...
January 9, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28054225/spectrum-and-burden-of-neglected-tropical-diseases-observed-in-an-infectious-and-tropical-diseases-unit-in-florence-italy-2000-2015
#11
Lorenzo Zammarchi, Iacopo Vellere, Leonardo Stella, Filippo Bartalesi, Marianne Strohmeyer, Alessandro Bartoloni
Neglected tropical diseases (NTDs) are a diverse group of acute and chronic conditions with distinct characteristics that thrive mainly among the poorest populations, almost exclusively in tropical countries. To evaluate the relevance and impact of NTDs in a temperate area, the number and features of patients diagnosed with NTDs at the Infectious and Tropical Diseases Unit (ITDU), Azienda Ospedaliero-Universitaria Careggi, Florence, Italy between 2000 and 2015 were retrospectively reviewed. Overall 289 NTD cases were diagnosed in 283 subjects accounting for 2...
January 4, 2017: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/28051760/contribution-to-the-diagnosis-and-treatment-of-life-threatening-parasitosis-caused-by-the-parasite-echinococcus-multilocularis
#12
Katarína Šimeková, Mária Szilágyiová, Daniela Antolová, Ladislav Laca, Hubert Polaček, Elena Nováková, Martin Števík, Róbert Rosoľanka
Echinococcosis is a serious parasitic disease that ends lethally in 95% of untreated infected patients. It was first diagnosed in Slovakia in the year 2000. It is caused by the larval stage of a tapeworm belonging to the genus Echinococcus, which was assigned to the group "A" of zoonoses in the year 2004. The number of new infections is rising because of increasing percentage of infected red foxes (Vulpes vulpes). Early and accurate diagnosis of infections with this parasite is essential for proper initiation of adequate therapy...
January 4, 2017: Vector Borne and Zoonotic Diseases
https://www.readbyqxmd.com/read/28045899/characterisation-of-antigen-b-protein-species-present-in-the-hydatid-cyst-fluid-of-echinococcus-canadensis-g7-genotype
#13
Ana Maite Folle, Eduardo S Kitano, Analía Lima, Magdalena Gil, Marcela Cucher, Gustavo Mourglia-Ettlin, Leo K Iwai, Mara Rosenzvit, Carlos Batthyány, Ana María Ferreira
The larva of cestodes belonging to the Echinococcus granulosus sensu lato (s.l.) complex causes cystic echinococcosis (CE). It is a globally distributed zoonosis with significant economic and public health impact. The most immunogenic and specific Echinococcus-genus antigen for human CE diagnosis is antigen B (AgB), an abundant lipoprotein of the hydatid cyst fluid (HF). The AgB protein moiety (apolipoprotein) is encoded by five genes (AgB1-AgB5), which generate mature 8 kDa proteins (AgB8/1-AgB8/5). These genes seem to be differentially expressed among Echinococcus species...
January 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28025118/detection-of-echinococcus-granulosus-and-echinococcus-ortleppi-in-bhutan
#14
Nirmal Kumar Thapa, Maria Teresa Armua-Fernandez, Dukpa Kinzang, Ratna B Gurung, Phuntsho Wangdi, Peter Deplazes
In this pilot study, fecal samples were collected from community dogs around slaughterhouses and from the city of Thimphu (n=138) as well as from carnivores in the forest area around a farm in Bhutan (n=28). Samples were analyzed microscopically for the presence of taeniid eggs by the floatation and sieving method. Further molecular analyses of 20 samples of community dogs positive for taeniid eggs confirmed 10 Echinococcus granulosus sensu lato and one Taenia hydatigena case. From 14 environmental fecal samples from the forest area positive for taeniid eggs, one contained E...
December 24, 2016: Parasitology International
https://www.readbyqxmd.com/read/28017635/use-of-fta-%C3%A2-card-methodology-for-sampling-and-molecular-characterization-of-echinococcus-granulosus-sensu-lato-in-africa
#15
Franck Boué, Ikhlass El Berbri, Vanessa Hormaz, Jean-Marc Boucher, Ahmed Bezeid El Mamy, Abdallah Traore, Ouafaa Fassi Fihri, Anne-Françoise Petavy, Allal Dakkak, Gérald Umhang
Cystic Echinococcosis is a parasitic disease caused by the cestode Echinococcus granulosus widely distributed in Africa. Monitoring of this parasite requires access to cyst samples on intermediate hosts observed at the slaughterhouse. In order to facilitate sampling in the field and analysis, the French National Reference Laboratory for Echinococcus spp. has developed a tissue derived from DNA sampling with FTA(®) card technology. The DNA samples were taken by applying the FTA(®) paper on the germinal layer after opening the cysts...
December 23, 2016: Experimental Parasitology
https://www.readbyqxmd.com/read/28012251/public-health-follow-up-of-suspected-exposure-to-echinococcus-multilocularis-in-southwestern-ontario
#16
L A Trotz-Williams, N J Mercer, J M Walters, D Wallace, B Gottstein, E Osterman-Lind, A K Boggild, A S Peregrine
In the 3 years since the first report of canine alveolar echinococcosis (AE) in Ontario, three additional cases have been diagnosed in the province. Of the four cases reported to date, three have had no known history of travel outside the province. It is possible that this development is an indication of previously unrecognized environmental contamination with Echinococcus multilocularis eggs in some areas of the province. If so, there is the potential for an emerging threat to human health. This article describes a local public health department's investigation of the possible exposure to E...
December 24, 2016: Zoonoses and Public Health
https://www.readbyqxmd.com/read/28008903/-thoracic-echinococcosis-complicated-by-arrosive-bleeding-from-great-vessels
#17
Sh N Khudaibergenov, Kh K Abrolov, R A Ibadov, O T Irisov, O D Eshonkhodzhaev, N T Tursunov, M M Mirolimov, B B Amanov, A T Mustafaev
No abstract text is available yet for this article.
2016: Khirurgiia
https://www.readbyqxmd.com/read/28004258/hints-for-control-of-infection-in-unique-extrahepatic-vertebral-alveolar-echinococcosis
#18
Jean-François Faucher, Cécile Descotes-Genon, Bruno Hoen, Joël Godard, Sophie Félix, Sébastien Aubry, Oleg Blagosklonov, Frédéric Grenouillet, Marie-Pascale Brientini, Carine Richou, Solange Bresson-Hadni, Catherine Chirouze
The prognosis of vertebral alveolar echinococcosis (AE) is poor. We report on the unique outcome of a patient with preexisting liver cirrhosis, in whom a diagnosis of vertebral AE was established on vertebral histopathology (D4 corporectomy in 2010 for paraplegia). Therapeutic drug monitoring of albendazole (ABZ) showed that a low dosage was appropriate. The patient recovered and ABZ withdrawal was decided in 2014, with no relapse 18 months later. In this patient, infection was purely or mainly localized in the dorsal spine, and this may have been favored by liver cirrhosis...
December 21, 2016: Infection
https://www.readbyqxmd.com/read/27994696/primary-hydatid-cyst-of-the-brain-in-a-child-a-case-report
#19
Alessia Imperato, Alessandro Consales, Marcello Ravegnani, Elio Castagnola, Roberto Bandettini, Andrea Rossi
BACKGROUND: Primary intracranial hydatid cyst is a rare location of human echinococcosis whose spontaneous, traumatic or even iatrogenic rupture, as in case of misdiagnosis, may cause anaphylactic reactions and dissemination. CASE REPORT: We discuss the management of a 9-year-old boy who was admitted to our Emergency Department with an intracranial hypertension syndrome. Head CT scan and brain MRI showed a huge intra-axial right temporo-parieto-occipital cyst with a marginal calcification, associated with left ventricular uncompensated hydrocephalus...
2016: Polish Journal of Radiology
https://www.readbyqxmd.com/read/27992434/watch-and-wait-management-of-inactive-cystic-echinococcosis-does-the-path-to-inactivity-matter-analysis-of-a-prospective-patient-cohort
#20
Marija Stojkovic, Kerstin Daniela Rosenberger, Franziska Steudle, Thomas Junghanss
BACKGROUND: Overdiagnosis and overtreatment are rarely discussed in the context of NTDs despite their relevance for patients under the care of health services with limited resources where the risks of therapy induced complications are often disproportionate to the benefit. The advantages of cyst staging-based management of patients with cystic echinococcosis (CE) are not yet fully explored. Questions are: Do inactive cysts (CE 4 and CE 5) need treatment and is there a difference between cysts which reach CE4 and CE5 naturally or by benzimidazole therapy? METHODOLOGY/PRINCIPAL FINDINGS: Analysis of long-term follow-up data from a prospective CE patient cohort of 223 patients of a national clinical center for echinococcosis...
December 2016: PLoS Neglected Tropical Diseases
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