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DEMINERALIZED

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https://www.readbyqxmd.com/read/29349022/arthroscopic-delivery-of-injectable-bone-graft-for-staged-revision-anterior-cruciate-ligament-reconstruction
#1
Kent T Yamaguchi, Gina M Mosich, Kristofer J Jones
Bone defects caused by femoral and tibial tunnel enlargement can pose a significant technical challenge when planning to perform revision anterior cruciate ligament reconstruction. A number of options have been described for managing osseous deficiencies, including the use of large autograft or allograft bone dowels to provide sufficient tunnel fill and subsequent structural support for revision surgery. These techniques can be time-consuming and technically demanding to ensure proper tunnel fill and press-fit stability of the bone graft...
December 2017: Arthroscopy Techniques
https://www.readbyqxmd.com/read/29346398/dual-function-of-edta-with-silver-nanoparticles-for-root-canal-treatment-a-novel-modification
#2
Juan M Martinez-Andrade, Miguel Avalos-Borja, Alfredo R Vilchis-Nestor, Luis O Sanchez-Vargas, Ernestina Castro-Longoria
The chelating and antimicrobial capacity of a novel modification of 17% EDTA with silver nanoparticles (AgNPs) (EDTA-AgNPs) was evaluated in-vitro for root canal treatment (RCT). The EDTA-AgNPs solution was characterized by UV-Vis spectroscopy, ζ-potential and high-resolution transmission electron microscopy (HRTEM). Antimicrobial capacity was evaluated against Candida albicans and Staphylococcus aureus in planktonic and biofilm cells by broth macrodilution (24 h) and XTT assays, (1, 10 and 30 min) respectively...
2018: PloS One
https://www.readbyqxmd.com/read/29344804/influence-of-highly-concentrated-fluoride-dentifrices-on-remineralization-characteristics-of-enamel-in-vitro
#3
R J Wierichs, S Westphal, J Lausch, H Meyer-Lueckel, M Esteves-Oliveira
OBJECTIVES: The aim of this in vitro study was to evaluate the role of highly fluoridated dentifrice on remineralization characteristics of lowly and highly pre-demineralized enamel artificial caries lesions. METHODS: Bovine enamel specimens were prepared (pH 4.95; 21 days) and discriminated in either lowly [L] or highly [H] pre-demineralized artificial caries lesions. Specimens with a mean ΔZbaseline,L (95% CI) of 5120 (4995; 5245) vol.% × μm and a mean ΔZbaseline,H of 8187 (8036; 8339) vol...
January 17, 2018: Clinical Oral Investigations
https://www.readbyqxmd.com/read/29342454/sodium-trimetaphosphate-as-a-novel-strategy-for-matrix-metalloproteinase-inhibition-and-dentin-remineralization
#4
Rafael Simões Gonçalves, Polliana Mendes Candia Scaffa, Marina Ciccone Giacomini, Cristina de Mattos Pimenta Vidal, Heitor Marques Honório, Linda Wang
The effect of sodium trimetaphosphate (STMP) as an antiproteolytic and remineralizing agent on demineralized dentin was evaluated in vitro. The inhibitory potential of STMP at 0.5, 1.5, 3.5, and 5% against recombinant matrix metalloproteinases (MMPs) MMPs-2 and -9 was assessed by zymography. To investigate its remineralization potential, 40 bovine root specimens were obtained and subjected to a demineralization protocol to produce caries-like dentin lesions. After that, dentin surfaces were divided into 3 areas: (1) mineralized (no treatment); (2) demineralized; and (3) demineralized/treated with STMP and submitted to a pH-cycling associated or not with STMP (1...
January 18, 2018: Caries Research
https://www.readbyqxmd.com/read/29339648/caries-preventive-effect-of-naf-naf-plus-tcp-naf-plus-cpp-acp-and-sdf-varnishes-on-sound-dentin-and-artificial-dentin-caries-in-vitro
#5
Richard J Wierichs, Sabrina Stausberg, Julian Lausch, Hendrik Meyer-Lueckel, Marcella Esteves-Oliveira
The aim of this study was to compare the caries-preventive effect of different fluoride varnishes on sound dentin as well as on artificial dentin caries-like lesions. Bovine dentin specimens (n = 220) with one sound surface (ST) and one artificial caries lesion (DT) were prepared and randomly allocated to 11 groups. The interventions before pH cycling were as follows: application of a varnish containing NaF (22,600 ppm F-; Duraphat [NaF0/NaF1]), NaF plus tricalcium phosphate (22,600 ppm F-; Clinpro White Varnish Mint [TCP0/TCP1]), NaF plus casein phosphopeptide-stabilized amorphous calcium phosphate complexes (CPP-ACP; 22,600 ppm F-; MI Varnish [CPP0/CPP1]), or silver diamine fluoride (SDF; 35,400 ppm F-; Cariestop 30% [SDF0/SDF1]) and no intervention (NNB/N0/N1)...
January 17, 2018: Caries Research
https://www.readbyqxmd.com/read/29335685/can-coloured-fluoride-gel-stain-demineralised-enamel
#6
Flávia Isaia Vieira, Fabio Zovico Maxnuck Soares, Rachel de Oliveira Rocha
PURPOSE: This study evaluated the colour changes of demineralized enamel after treatment with coloured fluoride gel. MATERIALS AND METHODS: Enamel blocks obtained from bovine incisors were submitted to artificial caries induction by pH cycling followed by fluoride gel applications (2% sodium fluoride, pH 6.8) using a colourless gel (control group), pink or blue gels. The enamel optical properties were evaluated by spectrophotometry, using the CIE L*a*b* system at baseline (sound enamel), after artificial caries induction (demineralised enamel) and after each of the five fluoride gel applications (weekly intervals)...
January 15, 2018: Oral Health & Preventive Dentistry
https://www.readbyqxmd.com/read/29333778/-remineralization-effect-of-casein-phosphopeptide-amorphous-calcium-phosphate-for-enamel-demineralization-a-system-review
#7
Wang Xiaotong, Rao Nanquan, Xie Jing, Zhao Yuming, Ge Lihong
OBJECTIVE: This study  aims  to  assess  the  remineralization effect of casein phosphopeptide (CPP)-amorphous calcium phosphate (ACP) on enamel demineralization by  performing  system review of  randomized  controlled  trials (RCT)  involving  the  treatment of enamel demineralization with  CPP-ACP. METHODS: The  study  was  developed  based  on  the 
Cochrane handbook  for  systematic  reviews of  interventions (Version 5...
December 1, 2017: Hua Xi Kou Qiang Yi Xue za Zhi, Huaxi Kouqiang Yixue Zazhi, West China Journal of Stomatology
https://www.readbyqxmd.com/read/29331472/influence-of-partially-demineralized-milk-proteins-on-rheological-properties-and-microstructure-of-acid-gels
#8
G H Meletharayil, H A Patel, L E Metzger, C Marella, T Huppertz
Innovative clean label processes employed in the manufacture of acid gels are targeted to modify the structure of proteins that contribute to rheological properties. In the present study, CO2-treated milk protein concentrate powder with 80% protein in dry matter (TMPC80) was mixed with nonfat dry milk (NDM) in different ratios for the manufacture of acid gels. Dispersions of NDM and TMPC80 that provided 100, 90, 70, and 40% of protein from NDM were reconstituted to 4.0% (wt/wt) protein and 12.0% (wt/wt) total solids...
January 10, 2018: Journal of Dairy Science
https://www.readbyqxmd.com/read/29330611/a%C3%A2-comparison-of-different-sealants-preventing-demineralization-around-brackets
#9
Stefanie Louise Coordes, Paul-Georg Jost-Brinkmann, Thomas Michael Präger, Theodosia Bartzela, Dominik Visel, Theresa Jäcker, Ralf Müller-Hartwich
AIM: Aim of the study was to compare how six different sealants resisted thermal, mechanical, and chemical loading in vitro. MATERIALS AND METHODS: In all, 120 extracted human, nondecayed molars were divided into six groups (20 samples each) and embedded in resin blocks. The buccal surfaces of the tooth samples were polished and divided into three areas. Area A contained the product to be analyzed, area B was covered with colorless nail varnish (negative control), and area C remained untreated (positive control)...
January 12, 2018: Journal of Orofacial Orthopedics, Fortschritte der Kieferorthopädie
https://www.readbyqxmd.com/read/29323776/remineralization-of-natural-human-carious-dentin-lesions-with-an-experimental-whisker-reinforced-atraumatic-restorative-treatment-composite
#10
Chao Zhang, Stephen D Campbell, Sabine H Dickens, Bin Yang
PURPOSE: To evaluate the remineralization of natural human dentin caries with an experimental whisker-reinforced Atraumatic Restorative Treatment (ART) composite. MATERIALS AND METHODS: Teeth with moderate active dentin caries were prepared with caries-disclosing dye and hand instruments, restored with ART or resin-modified glass ionomer cement (RM-GIC), and then wet sliced into 120-μm sections with 15 sections in each group. After taking transverse microradiographs and implementing digital image analysis to determine the "mineral-loss-before," each section was incubated in artificial saliva solution (pH = 7...
January 11, 2018: Journal of Prosthodontics: Official Journal of the American College of Prosthodontists
https://www.readbyqxmd.com/read/29310783/isolation-production-and-analysis-of-small-leucine-rich-proteoglycans-in-bone
#11
David J Kirby, Marian F Young
Small leucine-rich proteoglycans (SLRPs) are a unique class of proteins that exist in the extracellular matrix, playing key roles in cell proliferation and function. In bone, SLRPs such as biglycan and decorin affect osteogenesis and bone remodeling. Their essential role in this organ system has created the need to isolate these proteins for study. Bone presents unique obstacles to the study of proteins; however, through the use of demineralizing agents, efficient methods of the purification of proteoglycans have been developed...
2018: Methods in Cell Biology
https://www.readbyqxmd.com/read/29304422/bleaching-and-enamel-surface-interactions-resulting-from-the-use-of-highly-concentrated-bleaching-gels
#12
Guillermo Grazioli, Lisia Lorea Valente, Cristina Pereira Isolan, Helena Alves Pinheiro, Camila Gonçalves Duarte, Eliseu Aldrighi Münchow
Tooth bleaching is considered a non-invasive treatment, although the use of highly-concentrated products may provoke increased surface roughness and enamel demineralization, as well as postoperative sensitivity. Thus, the aim of this study was to investigate whether hydrogen peroxide (H2O2) concentration would affect tooth bleaching effectiveness and the enamel surface properties. Enamel/dentin bovine specimens (6 × 4 mm) were immersed in coffee solution for 7 days and evaluated with a spectrophotometer (Easyshade; baseline), using the CIEL*a*b* color parameters...
December 28, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/29303859/three-dimensional-radiological-assessment-of-alveolar-bone-volume-preservation-using-bovine-bone-xenograft
#13
Ali Al Qabbani, Sausan Al Kawas, Noor Hayati A Razak, Saad Wahby Al Bayatti, Hamid Hammad Enezei, A Rani Samsudin, Suzina Sheikh Ab Hamid
INTRODUCTION: Alveolar bone is critical in supporting natural teeth, dental implants as well as a removable and fixed prosthesis. Alveolar bone volume diminishes when its associated natural tooth is lost. OBJECTIVE: The aim of this study is to evaluate the effectiveness of bovine bone granules on alveolar bone socket augmentation for ridge preservation following atraumatic tooth extraction. MATERIALS AND METHODS: Twenty medically fit patients (12 males and 8 females aged between 18 and 40 years) who needed noncomplicated tooth extraction of 1 mandibular premolar tooth were divided randomly and equally into 2 groups...
January 4, 2018: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29301651/release-of-ictp-and-ctx-telopeptides-from-demineralized-dentin-matrices-effect-of-time-mass-and-surface-area
#14
Gianluca Turco, Milena Cadenaro, Tatjana Maravić, Andrea Frassetto, Eleonora Marsich, Annalisa Mazzoni, Roberto Di Lenarda, Franklin R Tay, David H Pashley, Lorenzo Breschi
OBJECTIVE: The present study evaluated the influence of time, mass and surface area of demineralized dentin collagen matrices on telopeptides release. The hypotheses tested were that the rates of ICTP and CTX release by matrix bound endogenous proteases are 1) not time-dependent, 2) unrelated to specimen mass, 3) unrelated to specimen surface area. METHODS: Non-carious human molars (N=24) were collected and randomly assigned to three groups. Dentin slabs with three different thicknesses: 0...
January 1, 2018: Dental Materials: Official Publication of the Academy of Dental Materials
https://www.readbyqxmd.com/read/29301123/a-randomized-in-situ-clinical-study-of-fluoride-dentifrices-on-enamel-remineralization-and-resistance-to-demineralization-effects-of-zinc
#15
Jonathan E Creeth, Ritu Karwal, Anderson T Hara, Domenick T Zero
This study aimed to determine the effect of zinc ions and F concentration in a dentifrice on remineralization of early caries lesions in situ and on resistance to subsequent demineralization. This was a single-center, 6-period, 6-product, blinded (examiner, subject, analyst), randomized (n = 62), crossover study. Products (all NaF) were: 0, 250, 1,150 and 1,426 ppm F (dose-response controls), "Zn-A" (0.3% ZnCl2, 1,426 ppm F), and "Zn-B" (as Zn-A, with high-foaming surfactants) in a conventional silica base...
January 5, 2018: Caries Research
https://www.readbyqxmd.com/read/29298447/dynamic-influence-of-ph-on-metalloproteinase-activity-in-human-coronal-and-radicular-dentin
#16
Stella F do Amaral, Polliana M C Scaffa, Renata D S Rodrigues, Douglas Nesadal, Marcia M Marques, Fernando N Nogueira, Maria Angela Pita Sobral
The aim of this study was to evaluate the effect of pH on the activation of matrix metalloproteinases (MMPs) of human coronal (CD) and radicular dentin (RD). CD and RD were pulverized to powder, and proteins were extracted with 1% phosphoric acid. The extracted proteins and the demineralized powder were separately incubated in the following solutions: 4-aminophenylmercuric acetate (control) or a buffer solution at different pHs (2.5, 4.5, 5.0, 6.0, and 7.0). After incubation, proteins were separated by electrophoresis to measure MMP activities by zymography...
January 4, 2018: Caries Research
https://www.readbyqxmd.com/read/29296111/effect-of-surface-treatment-on-enamel-cracks-after-orthodontic-bracket-debonding-er-cr-ysgg-laser-etching-versus-acid-etching
#17
Hassanali Ghaffari, Amirhossein Mirhashemi, Tahereh Baherimoghadam, Amir Azmi, Reza Rasooli
Objectives: This study sought to compare enamel cracks after orthodontic bracket debonding in the surfaces prepared with erbium, chromium: yttrium-scandium-galliumgarnet (Er,Cr:YSGG) laser and the conventional acid-etching technique. Materials and Methods: This in-vitro experimental study was conducted on 60 sound human premolars extracted for orthodontic purposes. The teeth were randomly divided into two groups (n=30). The teeth in group A were etched with 37% phosphoric acid gel, while the teeth in group B were subjected to Er,Cr:YSGG laser irradiation (gold handpiece, MZ8 tip, 50Hz, 4...
September 2017: Journal of Dentistry of Tehran University of Medical Sciences
https://www.readbyqxmd.com/read/29291465/deformation-regimes-of-collagen-fibrils-in-cortical-bone-revealed-by-in-situ-morphology-and-elastic-modulus-observations-under-mechanical-loading
#18
Peng-Fei Yang, Xiao-Tong Nie, Dong-Dong Zhao, Zhe Wang, Li Ren, Hui-Yun Xu, Joern Rittweger, Peng Shang
The mechanical properties of the bone play a decisive role in the resistance of the bone to fracture. Clinically, the quantity of the bone in the mineral phase has been considered as the gold-standard indicator for the risk of bone fracture. However, the bone is a complex tissue with a hierarchical-structure consisting of organic matrix, mineral hydroxyapatite, and water. Collagen comprises up to 90% of the organic matrix in the bone, and is vital for its mechanical behavior. To date, the morphological and mechanical responses of collagen fibrils in the bone matrix have been largely overlooked...
December 16, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/29285031/efficacy-of-modified-bioactive-glass-for-dentin-remineralization-and-obstruction-of-dentinal-tubules
#19
Mahshid Saffarpour, Maryam Mohammadi, Mohammadreza Tahriri, Azadeh Zakerzadeh
Objectives: This study assessed the efficacy of modified bioactive glass (MBG) for dentin remineralization and obstruction of dentinal tubules. Materials and Methods: Thirty-six dentin discs were made from 20 third molars and were stored in 12% lactic acid solution for two weeks to induce demineralization. The samples were divided into three groups (n=12): 1- BG, 2- BG modified with 5% strontium (Sr) and 3- BG modified with 10% Sr. After applying the BG, the samples were stored in artificial saliva for 7, 14 and 21 days...
July 2017: Journal of Dentistry of Tehran University of Medical Sciences
https://www.readbyqxmd.com/read/29284982/erosion-infiltration-technique-a-novel-alternative-for-masking-enamel-white-spot-lesion
#20
Praveen Muthuvel, Aarthi Ganapathy, Mohan Kumar Subramaniam, Vanita D Revankar
Enamel White spot lesions are early signs of demineralization under the intact enamel, which may or may not lead to the development of caries. An inactive white spot lesion might act as an arrested dental caries and impair the esthetic appearance by displaying a milky white color from its interior opacity. The first choice of treatment is remineralization with various remineralizing agents such as fluoride and ACP-CCP. Caries infiltration is a less invasive and effective method for arresting the white spot lesions...
November 2017: Journal of Pharmacy & Bioallied Sciences
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