Marnie F Hazlehurst, Kecia N Carroll, Paul E Moore, Adam A Szpiro, Margaret A Adgent, Logan C Dearborn, Allison R Sherris, Christine T Loftus, Yu Ni, Qi Zhao, Emily S Barrett, Ruby H N Nguyen, Shanna H Swan, Rosalind J Wright, Nicole R Bush, Sheela Sathyanarayana, Kaja Z LeWinn, Catherine J Karr
We examined associations between prenatal fine particulate matter (PM2.5 ), nitrogen dioxide (NO2 ), and ozone (O3 ) exposures and child respiratory outcomes through age 8-9 years in 1279 ECHO-PATHWAYS Consortium mother-child dyads. We averaged spatiotemporally modeled air pollutant exposures during four fetal lung development phases: pseudoglandular (5-16 weeks), canalicular (16-24 weeks), saccular (24-36 weeks), and alveolar (36+ weeks). We estimated adjusted relative risks (RR) for current asthma at age 8-9 and asthma with recent exacerbation or atopic disease, and odds ratios (OR) for wheezing trajectories using modified Poisson and multinomial logistic regression, respectively...
March 8, 2024: International Journal of Hygiene and Environmental Health