keyword
https://read.qxmd.com/read/37090316/pregnancy-in-women-with-cerebral-palsy
#21
H S Deeksha, Sandhya Pajai, Neema Acharya, Shazia Mohammad
Cerebral palsy is a permanent, non-progressive, irreversible, non-curable condition with high co-morbidities and lifelong complications. Brain lesions may be present at birth or shortly after that. It may be congenital or acquired, prenatal, or abnormal brain development. The damage to the brain is non-progressive. It mainly affects movement, coordination, strength, and posture. Cerebral palsy is believed to increase women's chance of unfavorable pregnancy outcomes. According to studies, the main outcome of cerebral palsy in pregnant women is premature birth...
March 2023: Curēus
https://read.qxmd.com/read/37029354/primary-bilateral-macronodular-adrenocortical-hyperplasia-pbmah-patient-with-armc5-mutations
#22
JOURNAL ARTICLE
Peng Tang, Jun Zhang, Song Peng, Xuzhi Yan, Yapeng Wang, Shuo Wang, Yao Zhang, Gaolei Liu, Jing Xu, Yiqiang Huang, Dianzheng Zhang, Qiuli Liu, Jun Jiang, Weihua Lan
BACKGROUND: Primary bilateral macronodular adrenocortical hyperplasia (PBMAH) is a highly heterogeneous disease with divergent manifestations ranging from asymptomatic subclinical Cushing syndrome (CS) to overt Cushing syndrome with severe complications. ARMC5 mutations occur in 20 to 55% PBMAH patients usually with more severe phenotypes. Different ARMC5 mutations might be associated with diverse phenotypes of PBMAH. CASE PRESENTATION: A 39-year-old man was admitted to our hospital with progressive weight gain and severe hypertension...
April 7, 2023: BMC Endocrine Disorders
https://read.qxmd.com/read/37020907/inequalities-in-health-complaints-20-year-trends-among-adolescents-in-scotland-1998-2018
#23
JOURNAL ARTICLE
Joanna C Inchley, Malachi Willis, Judith Mabelis, Judith Brown, Dorothy B Currie
This study examined trends in inequalities in health complaints among early adolescents in Scotland from 1998 to 2018. We analysed data from the Health Behaviour in School-aged Children (HBSC) survey conducted in Scotland in 1998, 2002, 2006, 2010, 2014 and 2018. A self-report questionnaire was administered in schools to a nationally representative sample of 11-, 13-, and 15-year-olds ( n  = 29,250). Health complaints were measured using a scale comprising four psychological symptoms (feeling low, feeling nervous, irritability and sleep difficulties) and four somatic symptoms (headache, backache, stomachache and dizziness)...
2023: Frontiers in Psychology
https://read.qxmd.com/read/36976340/are-serum-thyroid-hormone-parathormone-calcium-and-vitamin-d-levels-associated-with-lumbar-spine-degeneration-a-cross-sectional-observational-clinical-study
#24
JOURNAL ARTICLE
Murat Şakir Ekşi, Ömer Orhun, Yaren Nur Demir, Müjdat Kara, Gürkan Berikol, Emel Ece Özcan-Ekşi
PURPOSE: Low back pain (LBP) impairs the quality of life and rises healthcare costs. The association of spine degeneration and LBP with metabolic disorders have been reported, previously. However, metabolic processes related with spine degeneration remained unclear. We aimed to analyze whether serum thyroid hormones, parathormone, calcium, and vitamin D levels were associated with lumbar intervertebral disc degeneration (IVDD), Modic changes, and fatty infiltration in the paraspinal muscles...
March 28, 2023: European Spine Journal
https://read.qxmd.com/read/36949518/vitamin-e-induced-coagulopathy-in-a-young-patient-a-case-report
#25
JOURNAL ARTICLE
Ritika Abrol, Reshma Kaushik, Deepak Goel, Sonu Sama, Rajeev Mohan Kaushik, Mansi Kala
BACKGROUND: High-dose vitamin E intake is known to inhibit vitamin K-derived coagulation factor synthesis, which can cause serious bleeding events such as gastrointestinal bleeding and intracranial hemorrhage. We report a case of coagulopathy induced by marginally increased levels of vitamin E. CASE PRESENTATION: A 31-year-old Indian man presented with oral bleeding, black tarry stools, and bruising over his back. He had been taking non-steroidal anti-inflammatory drugs for low backache and vitamin E for hair loss...
March 23, 2023: Journal of Medical Case Reports
https://read.qxmd.com/read/36839965/therapeutic-efficacy-of-a-formulation-prepared-with-linum-usitatissimum-l-plantago-ovata-forssk-and-honey-on-uncomplicated-pelvic-inflammatory-disease-analyzed-with-machine-learning-techniques
#26
JOURNAL ARTICLE
Sana Qayyum, Arshiya Sultana, Md Belal Bin Heyat, Khaleequr Rahman, Faijan Akhtar, Amin Ul Haq, Batool Abdulelah Alkhamis, Mohammed Aedh Alqahtani, Reem M Gahtani
A single-blind double-dummy randomized study was conducted in diagnosed patients (n = 66) to compare the efficacy of Linseeds ( Linum usitatissimum L.), Psyllium ( Plantago ovata Forssk.), and honey in uncomplicated pelvic inflammatory disease (uPID) with standard drugs using experimental and computational analysis. The pessary group received placebo capsules orally twice daily plus a per vaginum cotton pessary of powder from linseeds and psyllium seeds, each weighing 3 gm, with honey (5 mL) at bedtime. The standard group received 100 mg of doxycycline twice daily and 400 mg of metronidazole TID orally plus a placebo cotton pessary per vaginum at bedtime for 14 days...
February 14, 2023: Pharmaceutics
https://read.qxmd.com/read/36750483/take-a-load-off-examining-partial-and-complete-cognitive-offloading-of-medication-information
#27
JOURNAL ARTICLE
Lauren L Richmond, Julia Kearley, Shawn T Schwartz, Mary B Hargis
Although cognitive offloading, or the use of physical action to reduce internal cognitive demands, is a commonly used strategy in everyday life, relatively little is known about the conditions that encourage offloading and the memorial consequences of different offloading strategies for performance. Much of the extant work in this domain has focused on laboratory-based tasks consisting of word lists, letter strings, or numerical stimuli and thus makes little contact with real-world scenarios under which engaging in cognitive offloading might be likely...
February 8, 2023: Cognitive Research: Principles and Implications
https://read.qxmd.com/read/36687193/ochronotic-arthropathy-of-bilateral-hip-joints-a-case-report
#28
Nicolas Yap San Min, Urba Rafi, Juan Wang, Bin He, Lei Fan
BACKGROUND: Ochronosis, also known as alkaptonuria, is a rare autosomal recessive self-metabolic disease arising from deficiency of homogentisate 1,2 dioxygenase enzyme. It affects several organs and muscoskeletal structures. We herein report a case of a patient who presented with severe hip arthropathy complicated with late stage ochronosis. CASE SUMMARY: A 56-year-old male patient was admitted in our department in 2019 with complaints of chronic low backache and left hip pain...
January 6, 2023: World Journal of Clinical Cases
https://read.qxmd.com/read/36578377/intradural-lumbar-disc-herniation-a-case-report-and-literature-review
#29
REVIEW
Cheng-Hsin Cheng, Md PhD Che-Chao Chang, Hung-Lin Lin, Hao-Yu Chuang, Ruey-Mo Lin, Ning-Ping Foo
STUDY DESIGN AND OBJECTION: Intradural disc herniation is a unusual disease associated with spinal surgery. The definitive diagnosis of intradural herniation depends on intraoperative findings. SUMMARY OF BACKGROUND DATA: We present the case of a 63-year-old woman with backache and left sciatica radiation for more than two months. The L2/3 laminectomy and discectomy were performed after magnetic resonance imaging (MRI) study; however, no disc rupture was noted during surgery...
December 2022: Heliyon
https://read.qxmd.com/read/36450457/early-physical-maturation-and-subjective-health-complaints-in-adolescent-girls-a-pooled-cross-sectional-analysis
#30
JOURNAL ARTICLE
Qiguo Lian, Ruili Li, Frank J Elgar, Qiru Su
BACKGROUND: Although adolescents are generally healthy, subjective health complaints (SHC) are common in this age group, especially in adolescent girls. We explored the association between early menarche and the frequency of psychosomatic symptoms and how this association varies between countries. METHODS: Our sample included 298 000 adolescent girls from 2002, 2006, 2010 and 2014 cycles of the Health Behaviour in School-aged Children (HBSC) study in 41 European and North American countries...
November 30, 2022: Journal of Epidemiology and Community Health
https://read.qxmd.com/read/36418181/clinical-and-laboratory-features-and-factors-predicting-disease-severity-in-pediatric-patients-with-hemorrhagic-fever-with-renal-syndrome-caused-by-hantaan-virus
#31
JOURNAL ARTICLE
Ruina Li, Jingkang Sun, Yuting Chen, Xuide Fan, Xiaoyun Wang, Xiaoge Zhang, Kun Zhang, Qunying Han, Zhengwen Liu
The clinical features and factors associated with disease severity in children with hemorrhagic fever with renal syndrome (HFRS) have not been well characterized. This study analyzed the clinical and laboratory factors associated with disease severity in children with HFRS caused by Hantaan virus. Data in pediatric patients with HFRS were retrospectively collected from Xi'an Children's Hospital over a 9-year period. Independent factors associated with disease severity were identified. Nomogram predicting disease severity was constructed based on variables filtered by feature selection...
November 23, 2022: Journal of Medical Virology
https://read.qxmd.com/read/36412397/a-histopathological-and-immunohistochemistry-analysis-of-endometrial-lesions-among-women-presenting-with-abnormal-uterine-bleeding
#32
JOURNAL ARTICLE
Nazia M Walvir, Safia Rana, Zeeba S Jairajpuri, Sujata Jetley, Aruna Nigam
OBJECTIVES: We aimed to histopathologically evaluate the morphological spectrum, apoptotic index (AI), and mitotic index (MI) of endometrial lesions in patients presenting with abnormal uterine bleeding (AUB). METHODS: A cross-sectional study was done over a period of 18 months where a total of 60 newly diagnosed cases of perimenopausal women presenting with AUB were included. All H and E stained pathology slides from the specimens were reviewed for initial histopathological evaluation and diagnosis...
2022: Journal of Cancer Research and Therapeutics
https://read.qxmd.com/read/36412372/correlation-between-obliquity-of-exiting-nerve-root-on-lateral-sagittal-mri-images-and-degenerative-spondylolisthesis
#33
JOURNAL ARTICLE
Dattaprasanna B Katikar
BACKGROUND: MRI has become the investigation of choice for patients of low back pain with radiculopathy. However, MRI does not consistently detect spondylolisthesis. In far lateral sagittalT2 MRI images, exiting nerve roots are seen descending vertically. We observed that the obliquity of these descending nerve roots may be related to spondylolisthesis. OBJECTIVE: Aim of this study is to evaluate the correlation between obliquity of exiting nerve root on MRI and lumbar instability on dynamic radiographs...
2022: Neurology India
https://read.qxmd.com/read/36336772/leptomeningeal-carcinomatosis-in-a-patient-with-recurrent-unresectable-squamous-cell-carcinoma-of-the-retromolar-trigone-a-brief-report
#34
JOURNAL ARTICLE
Jhansi Pattanaik, Varshu Goel, Priyanka Sehrawat, Ruchi Rathore, Rajesh Kumar Singh, Ajay Garg, Ahitagni Biswas
BACKGROUND: The reported incidence of leptomeningeal carcinomatosis is 3-8% in patients with solid tumours. More commonly, it has been described in the setting of advanced cancers of the lung, breast and malignant melanoma. CASE PRESENTATION: A 50-year-old diabetic patient with recurrent unresectable squamous cell carcinoma (SCC) of the right retromolar trigone (rT4bN0M0) presented with severe low backache and weakness in bilateral lower limbs 20 days after the completion of concurrent chemoradiotherapy...
November 7, 2022: Journal of the Egyptian National Cancer Institute
https://read.qxmd.com/read/36309563/association-of-single-child-family-with-subjective-health-complaints-in-children-and-adolescents
#35
JOURNAL ARTICLE
Hadith Rastad, Mostafa Qorbani, Kumars Pourrostami, Fatemeh Ochi, Ali Sheidayi, Hanieh-Sadat Ejtahed, Ehsan Seif, Nami Mohammadian Khonsari, Armita Mahdavi-Gorabi, Ramin Heshmat, Roya Kelishadi
The number of single-child families has been increasing across developing countries during the last decades. We aimed to examine the association between being a single child (SC) and subjective health complaints (SHCs) in Iranian children and adolescents. This study was conducted as a part of the fifth survey of a national surveillance program entitled Childhood and Adolescence Surveillance and Prevention of Adult Non-communicable disease (CASPIAN-V). This national survey included a total of 14,400 students 7-18 years and their parents from rural and urban areas in 30 provinces of Iran...
October 29, 2022: Scientific Reports
https://read.qxmd.com/read/36306669/prevalence-and-quality-of-life-burden-of-vasomotor-symptoms-associated-with-menopause-a-european-cross-sectional-survey
#36
JOURNAL ARTICLE
Rossella E Nappi, Emad Siddiqui, Lora Todorova, Carol Rea, Eric Gemmen, Neil M Schultz
OBJECTIVES: To determine, in a European cohort, the prevalence and health-related quality-of-life (QOL) burden of moderate-to-severe vasomotor symptoms (VMS) in postmenopausal women, and among subgroups of women not taking hormone therapy (HT). STUDY DESIGN: Screening surveys were sent to a random sample of women aged 40-65 years; those meeting the inclusion criteria completed the full questionnaire. Women with successfully treated VMS or breast cancer or who were receiving HT for medical conditions were excluded...
September 24, 2022: Maturitas
https://read.qxmd.com/read/36163757/aml-034-granulocytic-sarcoma-disguised-as-lymphoblastic-lymphoma
#37
JOURNAL ARTICLE
Mona Taalab, Raghda Khalifa, Dalia Salem
CONTEXT: Acute myeloid leukemia (AML) is a malignant clonal disease of hematopoietic stem cells affecting the blood and bone marrow. Granulocytic sarcoma (chloroma) is a rare disease characterized by an extramedullary myeloid cell mass with or without bone marrow infiltration. OBJECTIVE: We report a case of AML presented with granulocytic sarcoma causing cord compression. PATIENTS: An 18-year-old male presented in January 2022 with acute onset and progressive low backache and lower limb weakness with no history of associated trauma...
October 2022: Clinical Lymphoma, Myeloma & Leukemia
https://read.qxmd.com/read/36134572/avascular-necrosis-of-femur-as-a-complication-of-cushing-s-syndrome-due-to-adrenocortical-carcinoma
#38
REVIEW
Atul Anand, Chandan K Jha, Prashant K Singh, Upasana Sinha, Abhirami Ganesh, Punam P Bhadani
A wide range of clinical presentations for Cushing's syndrome has been described in the literature. Avascular necrosis of femur is a well-recognized complication of excessive glucocorticoid administration, but its occurrence due to endogenous hypercortisolism is rare. We present the case of a 47-year-old male who presented to us with severe low backache, hypertension, uncontrolled diabetes, and other signs and symptoms of Cushing's syndrome. Hormonal evaluation confirmed hypercortisolism, and a contrast-enhanced computed tomography of the abdomen localized the lesion in the left adrenal gland...
September 22, 2022: American Surgeon
https://read.qxmd.com/read/35703159/rare-presentation-of-meningitis-due-to-lumbar-facetal-septic-abscess-a-case-report
#39
JOURNAL ARTICLE
Guna Pratheep Kalanjiyam, Rajasekaran Shanmuganathan, Ajoy Prasad Shetty, Rishi Mugesh Kanna, Pushpa Bhari Thippesamy, Dilip Chand Raja
CASE: An elderly obese woman with comorbidities presented with acute-onset altered sensorium. She was diagnosed with meningitis and started on empirical antibiotics. She became oriented after 48 hours and mentioned that she had severe low backache in the previous week. Examination revealed bilateral lower limb weakness. Magnetic resonance imaging showed L3-L4 lumbar facetal abscess (LFA) with epidural extension. Posterior instrumented decompression was performed. Tissue culture grew Enterococcus, and the patient was administered vancomycin and linezolid...
April 1, 2022: JBJS Case Connector
https://read.qxmd.com/read/35443412/a-case-series-on-neuropathogenic-nature-of-an-ancient-disease-tuberculosis
#40
JOURNAL ARTICLE
Shivaraj Hadimani, Puneet Saxena, Suresh Kumar Yadav, Manish Kumar, Chandan Kumar Dash
Tuberculosis is one of the oldest diseases known to affect humans and the top cause of infectious death worldwide caused by M. tuberculosis complex. Tuberculosis may be pulmonary, extra-pulmonary or both. Nervous system tuberculosis is relatively rare and has protean nature of symptoms so poses diagnostic difficulty. Neurological manifestations of tuberculosis includes 1) intracranial 2) spinal 3) peripheral nerve tuberculosis. Central nervous system tuberculosis accounts about 5% of extra pulmonary cases and 1% all tuberculosis...
April 2022: Journal of the Association of Physicians of India
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