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https://www.readbyqxmd.com/read/29457955/a-quality-project-for-radiation-reduction-in-the-cath-lab
#1
Michel de Ceuninck, Philip Muyldermans, Stefaan van de Walle, Bernard Bergez, Rik Haspeslagh, Francis Stammen, Karl Dujardin
The radiation exposure in the cath lab of patients, cardiologists, and nurses was measured during three consecutive periods of 8 weeks. The first 8 weeks the baseline radiation exposure was obtained. In the second period standard incidences for coronarography and frame rate were changed, without compromising the image quality of the examination. In the third period, a pelvic shield covered the lower part of the patient. This pilot quality project demonstrates that further significant reduction in radiation exposure of 37% is possible for patients...
February 19, 2018: Acta Cardiologica
https://www.readbyqxmd.com/read/29457926/the-contribution-of-theory-to-the-design-delivery-and-evaluation-of-interprofessional-curricula-beme-guide-no-49
#2
Sarah Hean, Christopher Green, Elizabeth Anderson, Debra Morris, Carol John, Richard Pitt, Cath O'Halloran
BACKGROUND: Interprofessional curricula have often lacked explicit reference to theory despite calls for a more theoretically informed field that illuminates curricular assumptions and justifies curricular practices. AIM: To review the contributions of theory to the design, delivery, and evaluation of interprofessional curricula. METHODS: Four databases were searched (1988-2015). Studies demonstrating explicit and a high-quality contribution of theory to the design, delivery or evaluation of interprofessional curricula were included...
February 19, 2018: Medical Teacher
https://www.readbyqxmd.com/read/29456707/resveratrol-induces-autophagic-apoptosis-via-the-lysosomal-cathepsin-d-pathway-in-human-drug-resistant-k562-adm-leukemia-cells
#3
Zhewen Zhang, Zhuan Liu, Jing Chen, Juan Yi, Juan Cheng, Wangqing Dun, Hulai Wei
The aim of the present study was to investigate the crosstalk between resveratrol (Res)-induced autophagy and apoptosis, and the molecular pathway by which autophagy leads to apoptotic death in drug-resistant K562/ADM leukemia cells. The viability of K562/ADM cells was determined using the MTT assay. The formation of autophagic vacuoles was detected using transmission electron microscopy and monodansylcadaverine (MDC) staining. Cell apoptosis was evaluated using flow cytometry. The expression of apoptosis- or autophagy-associated proteins was measured using western blotting...
March 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29441275/improving-the-cardiac-cath-lab-interventional-imaging-eco-system
#4
EDITORIAL
Benjamin R Ciske, Michael A Speidel, Amish N Raval
No abstract text is available yet for this article.
January 2018: Translational Pediatrics
https://www.readbyqxmd.com/read/29438221/plasma-concentration-of-biomarkers-reflecting-endothelial-cell-and-glycocalyx-damage-are-increased-in-patients-with-suspected-st-elevation-myocardial-infarction-complicated-by-cardiogenic-shock
#5
Martin Frydland, Sisse Rye Ostrowski, Jacob Eifer Møller, Edina Hadziselimovic, Lene Holmvang, Hanne Berg Ravn, Lisette Okkels Jensen, Anna Sina Pettersson, Jesper Kjaergaard, Matias Greve Lindholm, Pär Ingemar Johansson, Christian Hassager
BACKGROUND: Mortality in ST-elevation myocardial infarction (STEMI)-patients developing cardiogenic shock (CS) during hospitalization is high. Catecholamines, ischemia, and inflammation (parameters present in CS) affect the endothelium. We hypothesized that plasma level of biomarkers reflecting endothelial damage would be associated with CS and mortality. METHODS: In 96% of 1467 consecutive patients with suspected STEMI, biomarkers reflecting endothelial cell- (soluble thrombomodulin, sTM) and glycocalyx- (syndecan-1) damage were measured on admission...
February 12, 2018: Shock
https://www.readbyqxmd.com/read/29429843/invasive-in-the-cath-lab-assessment-of-myocardial-ischemia-in-patients-with-coronary-artery-disease-when-does-the-gold-standard-not-apply
#6
REVIEW
Stefano Benenati, Giovanni Luigi De Maria, Roberto Scarsini, Italo Porto, Adrian P Banning
International guidelines recommend that revascularization for coronary artery disease (CAD) should be guided by evidence of myocardial ischemia. Fractional flow reserve (FFR) and instantaneous free wave ratio (iFR) are the main invasive indices for assessing the ischemic potential of angiographically intermediate coronary stenosis as a large body of evidence supports their routine application. Both indices have been tested and validated in patients with isolated stable CAD, but notably their application outside this specific context is a matter of debate and investigation...
January 31, 2018: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/29427965/decision-support-toolkit-for-integrated-analysis-and-design-of-reclaimed-water-infrastructure
#7
Eun Jung Lee, Craig S Criddle, Mengistu Geza, Tzahi Y Cath, David L Freyberg
Planning of water reuse systems is a complex endeavor. We have developed a software toolkit, IRIPT (Integrated Urban Reclaimed Water Infrastructure Planning Toolkit) that facilitates planning and design of reclaimed water infrastructure for both centralized and hybrid configurations that incorporate satellite treatment plants (STPs). The toolkit includes a Pipeline Designer (PRODOT) that optimizes routing and sizing of pipelines for wastewater capture and reclaimed water distribution, a Selector (SelWTP) that assembles and optimizes wastewater treatment trains, and a Calculator (CalcBenefit) that estimates fees, revenues, and subsidies of alternative designs...
January 30, 2018: Water Research
https://www.readbyqxmd.com/read/29419623/clinical-effectiveness-of-decongestive-treatments-on-excess-arm-volume-and-patient-centered-outcomes-in-women-with-early-breast-cancer-related-arm-lymphedema-a-systematic-review
#8
Eunice Jeffs, Emma Ream, Cath Taylor, Debra Bick
OBJECTIVE: To identify the effect of decongestive lymphedema treatment on excess arm volume or patient-centered outcomes in women presenting within either 12 months or a mean nine months of developing arm lymphedema following breast cancer treatment. INTRODUCTION: Lymphedema is a common consequence of breast cancer treatment requiring life-long treatment to reduce symptoms and prevent complications. Currently, evidence to inform the optimal decongestive lymphedema treatment package is lacking...
February 2018: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/29411518/a-retrospective-study-of-radiation-dose-measurements-comparing-different-cath-lab-x-ray-systems-in-a-sample-population-of-patients-undergoing-percutaneous-coronary-intervention-for-chronic-total-occlusions
#9
Andrew H McNeice, Matthew Brooks, Colm G Hanratty, Michael Stevenson, James C Spratt, Simon J Walsh
OBJECTIVES: A retrospective study was performed to investigate if the generation of X-ray system used was an independent factor for radiation dose in chronic total occlusion (CTO) percutaneous coronary intervention (PCI). BACKGROUND: PCI procedures for CTOs are known to be associated with higher doses of radiation. The authors suspected progressive reductions in radiation doses for CTO PCI as newer X-ray systems were introduced into clinical practice. METHODS: Procedures performed over a five-year period by three interventional cardiologists were retrospectively reviewed...
February 7, 2018: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29407895/innate-antiviral-immune-response-against-infectious-bronchitis-virus-and-involvement-of-prostaglandin-e2-in-the-uterine-mucosa-of-laying-hens
#10
M Elhamouly, T Terada, T Nii, N Isobe, Y Yoshimura
Infectious bronchitis virus (IBV) is an enveloped RNA virus that causes deformities in eggshells. The aim of this study was to investigate the innate immune response to IBV, and to determine whether prostaglandin (PG) E2, which is synthesized during inflammation, is involved in the innate immune response in the uterine mucosa. The effects of intra-oviductal inoculation with attenuated IBV (aIBV) on the expression of viral RNA recognition receptors and innate antiviral factors were examined by real-time PCR and immunohistochemistry, and on PGE2 levels by ELISA...
January 11, 2018: Theriogenology
https://www.readbyqxmd.com/read/29405602/perforations-and-how-to-manage-the-coronary-interventionalist-and-peripheral-interventionalist-working-together-for-a-solution
#11
EDITORIAL
Richard R Heuser
Perforations can occur in both peripheral and coronary interventional procedures potentially resulting in severe morbidity A readily available therapeutic option to treat perforations should be present in every cath lab that does coronary and peripheral procedures The use of a coagulated thrombus injection can be an effective treatment option, but if a major vessel is affected that must remain patent, one viable option is to administer the patients' own clotted blood to recanalize the vessel without permanent sequelae...
February 1, 2018: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29405302/changes-in-plasma-unit-distributions-to-hospitals-over-a-10-year-period
#12
Jansen N Seheult, Beth Shaz, Marjorie Bravo, Harry Croxon, Dana Devine, Cheryl Doncaster, Stephen Field, Peter Flanagan, Marc Germain, Yves Grégoire, Hany Kamel, Matthew Karafin, Nancy Kelting, Marc Lewis, Cath O'Brien, Michael F Murphy, Susan Rossmann, Merlyn Sayers, Eilat Shinar, Minoko Takanashi, Kjell Titlestad, Mark H Yazer
BACKGROUND: There are many influences on a hospital's demand for plasma. Pharmaceuticals are now being administered for many indications instead of plasma, although trauma resuscitation now emphasizes increased and early intervention with plasma. This multinational study evaluated changes in blood center plasma unit distributions over a 10-year period. STUDY DESIGN AND METHODS: Data on the total number and the ABO groups of plasma unit distributions were obtained from nine American blood collectors (ABCs) and nine national or provincial blood services (NPBS) from 2007 through 2016...
February 5, 2018: Transfusion
https://www.readbyqxmd.com/read/29401287/opiate-use-in-the-cath-lab-a-transatlantic-divide-and-new-focus-of-research
#13
Rohan Shah, Ajay J Kirtane, John W McEvoy
No abstract text is available yet for this article.
February 1, 2018: European Heart Journal
https://www.readbyqxmd.com/read/29397359/operational-efficiency-and-productivity-improvement-initiatives-in-a-large%C3%A2-cardiac%C3%A2-catheterization-laboratory
#14
Grant W Reed, Scott Hantz, Rebecca Cunningham, Amar Krishnaswamy, Stephen G Ellis, Joe Rak, Samir R Kapadia
OBJECTIVES: This study sought to report outcomes from an efficiency improvement project in a large cardiac cath lab. BACKGROUND: Operational inefficiencies are common in the cath lab, yet solutions are challenging. A detailed report describing and providing solutions for these inefficiencies may be valuable in guiding improvements in productivity. METHODS: In this observational study, the authors report metrics of efficiency before and after a cath lab quality improvement program in June 2014...
January 25, 2018: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29392557/the-antimicrobial-potential-of-a-new-derivative-of-cathelicidin-from-bungarus-fasciatus-against-methicillin-resistant-staphylococcus-aureus
#15
Mercedeh Tajbakhsh, Abdollah Karimi, Abolghasem Tohidpour, Naser Abbasi, Fatemeh Fallah, Maziar Mohammad Akhavan
Cathelicidins are a family of antimicrobial peptides which exhibit broad antimicrobial activities against antibiotic-resistant bacteria. Considering the progressive antibiotic resistance, cathelicidin is a candidate for use as an alternative approach to treat and overcome the challenge of antimicrobial resistance. Cathelicidin-BF (Cath-BF) is a short antimicrobial peptide, which was originally extracted from the venom of Bungarus fasciatus. Recent studies have reported that Cath-BF and some related derivatives exert strong antimicrobial and weak hemolytic properties...
February 2018: Journal of Microbiology / the Microbiological Society of Korea
https://www.readbyqxmd.com/read/29390968/general-practitioner-contributions-to-achieving-sustained-healthcare-for-offenders-a-qualitative-study
#16
Cath Quinn, Katie Denman, Philippa Smithson, Christabel Owens, Rod Sheaff, John Campbell, Ian Porter, Jill Annison, Richard Byng
BACKGROUND: Offenders frequently have substantial healthcare needs and, like many other socially marginalised groups, often receive healthcare in inverse proportion to their needs. Improved continuity of healthcare over time could contribute to addressing these needs. General Practitioners need to be able to support people with complex social and medical problems, even in systems that are not specifically designed to manage individuals with such degrees of complexity. We aimed to examine offenders' perspectives on factors that contributed to, or worked against, creating and sustaining their access to healthcare...
February 2, 2018: BMC Family Practice
https://www.readbyqxmd.com/read/29390004/the-development-and-application-of-bioinformatics-core-competencies-to-improve-bioinformatics-training-and-education
#17
Nicola Mulder, Russell Schwartz, Michelle D Brazas, Cath Brooksbank, Bruno Gaeta, Sarah L Morgan, Mark A Pauley, Anne Rosenwald, Gabriella Rustici, Michael Sierk, Tandy Warnow, Lonnie Welch
Bioinformatics is recognized as part of the essential knowledge base of numerous career paths in biomedical research and healthcare. However, there is little agreement in the field over what that knowledge entails or how best to provide it. These disagreements are compounded by the wide range of populations in need of bioinformatics training, with divergent prior backgrounds and intended application areas. The Curriculum Task Force of the International Society of Computational Biology (ISCB) Education Committee has sought to provide a framework for training needs and curricula in terms of a set of bioinformatics core competencies that cut across many user personas and training programs...
February 2018: PLoS Computational Biology
https://www.readbyqxmd.com/read/29348485/motor-signatures-of-emotional-reactivity-in-frontotemporal-dementia
#18
Charles R Marshall, Chris J D Hardy, Lucy L Russell, Camilla N Clark, Rebecca L Bond, Katrina M Dick, Emilie V Brotherhood, Cath J Mummery, Jonathan M Schott, Jonathan D Rohrer, James M Kilner, Jason D Warren
Automatic motor mimicry is essential to the normal processing of perceived emotion, and disrupted automatic imitation might underpin socio-emotional deficits in neurodegenerative diseases, particularly the frontotemporal dementias. However, the pathophysiology of emotional reactivity in these diseases has not been elucidated. We studied facial electromyographic responses during emotion identification on viewing videos of dynamic facial expressions in 37 patients representing canonical frontotemporal dementia syndromes versus 21 healthy older individuals...
January 18, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29346666/gypsy-roma-and-traveller-access-to-and-engagement-with-health-services-a-systematic-review
#19
Alison McFadden, Lindsay Siebelt, Anna Gavine, Karl Atkin, Kerry Bell, Nicola Innes, Helen Jones, Cath Jackson, Haggi Haggi, Steve MacGillivray
Background: Gypsy, Roma and Traveller people represent the most disadvantaged minority groups in Europe, having the poorest health outcomes. This systematic review addressed the question of how Gypsy, Roma and Traveller people access healthcare and what are the best ways to enhance their engagement with health services. Methods: Searches were conducted in 21 electronic databases complemented by a focussed Google search. Studies were included if they had sufficient focus on Gypsy, Roma or Traveller populations; reported data pertinent to healthcare service use or engagement and were published in English from 2000 to 2015...
February 1, 2018: European Journal of Public Health
https://www.readbyqxmd.com/read/29345604/a-new-approach-of-three-dimensional-guidance-in-paediatric-cath-lab-segmented-and-tessellated-heart-models-for-cardiovascular-interventions-in-chd
#20
Nicole Ehret, Muhannad Alkassar, Sven Dittrich, Robert Cesnjevar, André Rüffer, Michael Uder, Oliver Rompel, Matthias Hammon, Martin Glöckler
BACKGROUND: Optimal imaging is essential for catheter-based interventions in CHD. The three-dimensional models in volume-rendering technique currently in use are not standardised. This paper investigates the feasibility and impact of novel three-dimensional guidance with segmented and tessellated three-dimensional heart models in catheterisation of CHD. In addition, a nearly radiation-free two- to three-dimensional registration and a biplane overlay were used. Methods and results We analysed 60 consecutive cases in which segmented tessellated three-dimensional heart models were merged with live fluoroscopy images and aligned using the tracheal bifurcation as a fiducial mark...
January 18, 2018: Cardiology in the Young
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