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https://www.readbyqxmd.com/read/28339728/comparative-expression-of-host-defense-peptides-in-turkey-poults
#1
Shaimaa K Hamad, Sungwon Kim, Samer W El-Kadi, Eric A Wong, Rami A Dalloul
Host defense peptides (HDPs) are a large group of small, positively charged peptides that play an important role in innate immunity, particularly at early ages when other components of the immune system have not fully developed. There are 3 classes of avian HDPs: avian beta defensins (AvBDs), cathelicidins (Cath), and liver-expressed antimicrobial peptide 2 (LEAP-2). The objective was to compare expression of HDP mRNAs in male turkey poults at day of hatch (d 0), d 7, d 14, d 21 and d 28 from the thymus, spleen, bursa, duodenum, jejunum, and ileum...
February 22, 2017: Poultry Science
https://www.readbyqxmd.com/read/28334456/a-systematic-review-of-combined-student-and-parent-based-programs-to-prevent-alcohol-and-other-drug-use-among-adolescents
#2
REVIEW
Nicola C Newton, Katrina E Champion, Tim Slade, Cath Chapman, Lexine Stapinski, Ina Koning, Zoe Tonks, Maree Teesson
ISSUES: Alcohol and other drug use among adolescents is a serious concern, and effective prevention is critical. Research indicates that expanding school-based prevention programs to include parenting components could increase prevention outcomes. This paper aims to identify and describe existing combined student- and parent-based programs for the prevention of alcohol and other drug use to evaluate the efficacy of existing programs. APPROACH: The PsycINFO, Medline, Central Register of Controlled trials and Cochrane databases were searched in April 2015 and additional articles were obtained from reference lists...
March 23, 2017: Drug and Alcohol Review
https://www.readbyqxmd.com/read/28327572/the-role-of-genetic-counsellors-in-genomic-healthcare-in-the-united-kingdom-a-statement-by-the-association-of-genetic-nurses-and-counsellors
#3
Anna Middleton, Peter Marks, Anita Bruce, Liwsi K Protheroe-Davies, Cath King, Oonagh Claber, Catherine Houghton, Claire Giffney, Rhona Macleod, Claire Dolling, Sue Kenwrick, Diana Scotcher, Georgina Hall, Christine Patch, Laura Boyes
In the United Kingdom, genetic counsellors work together with clinical geneticists and clinical scientist colleagues within specialist genetics services, but they also often work in multidisciplinary teams (MDTs) outside of such services. There, they contribute genetic knowledge together with expert understanding of how to communicate genetic information effectively. They can offer education and support to the MDT, while providing management advice for both affected patients and the extended at-risk family members...
March 22, 2017: European Journal of Human Genetics: EJHG
https://www.readbyqxmd.com/read/28296143/targeting-the-safe-zone
#4
Andrea Mignatti, Patricia Friedmann, David Paul Slovut
OBJECTIVE: The aim of this study was to assess the effectiveness of a quality improvement (QI) program in reducing vascular complications during cardiac catheterization. BACKGROUND: Vascular access complications during cardiac catheterization are associated with higher morbidity and mortality. We implemented a QI program focused on using micropuncture techniques and targeting the "safe zone," an area below the inferior border of the inferior epigastric artery and above the inferior border of the femoral head, for femoral artery puncture...
March 15, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28293489/a-novel-strategy-to-supercharge-a-deep-inferior-epigastric-artery-perforator-flap-after-port-a-cath-removal
#5
Chad M Teven, Adrian S H Ooi, David W Chang, David H Song
Autologous breast reconstruction using the deep inferior epigastric artery perforator (DIEP) flap has become increasingly popular because of its unique advantages. However, compared with some other forms of abdominal-based autologous reconstruction, DIEP flaps are associated with an increased risk of venous congestion. Many techniques-or lifeboats-have been introduced to diagnose and treat this potentially devastating complication. In this case report, we describe a novel strategy to augment venous drainage when venous congestion is encountered...
December 2016: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/28288596/needles-jabs-and-jags-a-qualitative-exploration-of-barriers-and-facilitators-to-child-and-adult-immunisation-uptake-among-gypsies-travellers-and-roma
#6
Cath Jackson, Helen Bedford, Francine M Cheater, Louise Condon, Carol Emslie, Lana Ireland, Philippa Kemsley, Susan Kerr, Helen J Lewis, Julie Mytton, Karen Overend, Sarah Redsell, Zoe Richardson, Christine Shepherd, Lesley Smith, Lisa Dyson
BACKGROUND: Gypsies, Travellers and Roma (referred to as Travellers) are less likely to access health services including immunisation. To improve immunisation rates, it is necessary to understand what helps and hinders individuals in these communities in taking up immunisations. This study had two aims. 1. Investigate the views of Travellers in the UK on the barriers and facilitators to acceptability and uptake of immunisations and explore their ideas for improving immunisation uptake; 2...
March 14, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28271557/early-cardiac-catheterization-leads-to-shortened-pediatric-extracorporeal-membrane-oxygenation-run-duration
#7
Christopher R Burke, Titus Chan, Agustin E Rubio, David M McMullan
OBJECTIVE: Cardiac catheterization in patients receiving extracorporeal life support (ECLS) has previously been shown to be safe and, in many cases, therapeutic. However, the influence of cardiac catheterization on clinical outcomes in this patient population has not been clearly defined. METHODS: A single institution, retrospective review of all pediatric cardiac ECLS patients who underwent cardiac catheterization between January 2006 and September 2015 was performed...
March 8, 2017: Journal of Interventional Cardiology
https://www.readbyqxmd.com/read/28268814/a-machine-learning-framework-for-auto-classification-of-imaging-system-exams-in-hospital-setting-for-utilization-optimization
#8
Meru A Patil, Ravindra B Patil, P Krishnamoorthy, Jacob John
In clinical environment, Interventional X-Ray (IXR) system is used on various anatomies and for various types of the procedures. It is important to classify correctly each exam of IXR system into respective procedures and/or assign to correct anatomy. This classification enhances productivity of the system in terms of better scheduling of the Cath lab, also provides means to perform device usage/revenue forecast of the system by hospital management and focus on targeted treatment planning for a disease/anatomy...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28259143/training-on-domestic-violence-and-child-safeguarding-in-general-practice-a-mixed-method-evaluation-of-a-pilot-intervention
#9
Natalia V Lewis, Cath Larkins, Nicky Stanley, Eszter Szilassy, William Turner, Jessica Drinkwater, Gene S Feder
BACKGROUND: Children's exposure to domestic violence is a type of child maltreatment, yet many general practice clinicians remain uncertain of their child safeguarding responsibilities in the context of domestic violence. We developed an evidence-based pilot training on domestic violence and child safeguarding for general practice teams. The aim of this study was to test and evaluate its feasibility, acceptability and the direction of change in short-term outcome measures. METHODS: We used a mixed method design which included a pre-post questionnaire survey, qualitative analysis of free-text comments, training observations, and post-training interviews with trainers and participants...
March 4, 2017: BMC Family Practice
https://www.readbyqxmd.com/read/28249209/microbial-electrochemical-nutrient-recovery-in-anaerobic-osmotic-membrane-bioreactors
#10
Dianxun Hou, Lu Lu, Dongya Sun, Zheng Ge, Xia Huang, Tzahi Y Cath, Zhiyong Jason Ren
This study demonstrates that by incorporating a microbial electrochemical unit into an anaerobic osmotic membrane bioreactor (AnOMBR), the system addressed several challenges faced by traditional anaerobic membrane bioreactors and recovered biogas, nitrogen, and phosphorus while maintaining high effluent quality with low dissolved methane. The microbial recovery cell (MRC)-AnOMBR system showed excellent organic (>93%) and phosphorus removal (>99%) and maintained effluent COD below 20 mg/L. Furthermore, the reactor effectively recovered up to 65% PO4(3-) and 45% NH4(+) from the influent, which can be further improved if membranes with higher selectivity are used...
February 20, 2017: Water Research
https://www.readbyqxmd.com/read/28227009/a-machine-learning-framework-for-auto-classification-of-imaging-system-exams-in-hospital-setting-for-utilization-optimization
#11
Meru A Patil, Ravindra B Patil, P Krishnamoorthy, Jacob John, Meru A Patil, Ravindra B Patil, P Krishnamoorthy, Jacob John, Meru A Patil, Jacob John, Ravindra B Patil, P Krishnamoorthy
In clinical environment, Interventional X-Ray (IXR) system is used on various anatomies and for various types of the procedures. It is important to classify correctly each exam of IXR system into respective procedures and/or assign to correct anatomy. This classification enhances productivity of the system in terms of better scheduling of the Cath lab, also provides means to perform device usage/revenue forecast of the system by hospital management and focus on targeted treatment planning for a disease/anatomy...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28214966/anomalous-coronary-arteries-and-myocardial-bridges-risk-stratification-in-children-using-novel-cardiac-catheterization-techniques
#12
Hitesh Agrawal, Silvana Molossi, Mahboob Alam, S Kristen Sexson-Tejtel, Carlos M Mery, E Dean McKenzie, Charles D Fraser, Athar M Qureshi
The evaluation of the vast majority of children with anomalous aortic origin of a coronary artery (AAOCA) and/or myocardial bridges is performed with non-invasive testing. However, a subset of these patients may benefit from invasive testing for risk stratification. All patients included in the Coronary Anomalies Program (CAP) at Texas Children's Hospital who underwent cardiac catheterization were included. Techniques included selective coronary angiograms (SCA), intravascular ultrasound (IVUS), and fractional flow reserve (FFR) measurements with provocative testing using adenosine and/or dobutamine infusions...
February 18, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/28191656/utility-and-safety-of-combined-interventional-catheterization-and-electrophysiology-procedures-in-a-children-s-hospital
#13
S Yukiko Asaki, Jeffrey W Orcutt, Christina Y Miyake, Henri Justino, Caridad M DE LA Uz, Jeffrey J Kim, Santiago O Valdes, Athar M Qureshi
BACKGROUND: Interventional cardiac catheterization (cath) and electrophysiology (EP) procedures are not routinely performed together. There are several perceived barriers affecting this practice, though there are also advantages for both the patient and practitioner to a combined approach. METHODS: This was a single center retrospective study reviewing combined cath and EP procedures with a pre-procedural intention to intervene at Texas Children's Hospital from 2001 to 2014...
February 13, 2017: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/28190783/a-retrospective-analysis-of-catheter-based-sources-in-intravascular-brachytherapy
#14
J DeCunha, C Janicki, S A Enger
PURPOSE: Coronary artery disease involves the deposition of plaque along the walls of a coronary artery leading to narrowed or blocked vessels (stenosis) and is one of the main causes of death in developed countries. Percutaneous transluminal coronary angioplasty (PTCA) is used to reverse stenosis. Restenosis (renarrowing) of the treated vessel is a major complication of PTCA. A metal mesh tube (stent) can be placed inside the vessel to prevent restenosis. Tissue stress incurred during PTCA and stenting can provoke neointimal cell proliferation leading to in-stent restenosis (ISR)...
February 10, 2017: Brachytherapy
https://www.readbyqxmd.com/read/28163163/mixed-micelles-of-lipoic-acid-chitosan-poly-ethylene-glycol-and-distearoylphosphatidylethanolamine-poly-ethylene-glycol-for-tumor-delivery
#15
Zeeneh Elsaid, Kevin M G Taylor, Sanyogitta Puri, Cath A Eberlein, Khuloud Al-Jamal, Jie Bai, Rebecca Klippstein, Julie Tzu-Wen Wang, Ben Forbes, Jasminder Chana, Satyanarayana Somavarapu
Many chemotherapeutics suffer from poor aqueous solubility and tissue selectivity. Distearoylphosphatidylethanolamine-poly(ethylene glycol) (DSPE-PEG) micelles are a promising formulation strategy for the delivery of hydrophobic anticancer drugs. However, storage and in vivo instability restrict their use. The aim of this study was to prepare mixed micelles, containing a novel polymer, lipoic acid-chitosan-poly(ethylene glycol) (LACPEG), and DSPE-PEG, to overcome these limitations and potentially increase cancer cell internalisation...
April 1, 2017: European Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28150234/cath-gene3d-generation-of-the-resource-and-its-use-in-obtaining-structural-and-functional-annotations-for-protein-sequences
#16
Natalie L Dawson, Ian Sillitoe, Jonathan G Lees, Su Datt Lam, Christine A Orengo
This chapter describes the generation of the data in the CATH-Gene3D online resource and how it can be used to study protein domains and their evolutionary relationships. Methods will be presented for: comparing protein structures, recognizing homologs, predicting domain structures within protein sequences, and subclassifying superfamilies into functionally pure families, together with a guide on using the webpages.
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28149318/efficacy-and-safety-of-tornus-catheter-in-percutaneous-coronary-intervention-of-hard-or-balloon-uncrossable-chronic-total-occlusion
#17
Mohsen Mohandes, Sergio Rojas, Jordi Guarinos, Francisco Fernández, Xavier Oliva, Marianela Noueched, Alfredo Bardaji
BACKGROUND: Balloon advancement and dilation through chronic total occlusion segment could be challenging in some cases after successful wire crossing. The purpose of this study was to evaluate efficacy and safety of Tornus catheter (Asahi Intecc; Aichi, Japan) in percutaneous coronary intervention of chronic total occlusion in hard or balloon-uncrossable chronic total occlusion. METHODS: The present study is a retrospective and descriptive analysis of 14 hard or balloon-uncrossable chronic total occlusions treated percutaneously in our catheterization laboratory (cath lab)...
July 2016: ARYA Atherosclerosis
https://www.readbyqxmd.com/read/28137783/juggling-confidentiality-and-safety-a-qualitative-study-of-how-general-practice-clinicians-document-domestic-violence-in-families-with-children
#18
Jessica Drinkwater, Nicky Stanley, Eszter Szilassy, Cath Larkins, Marianne Hester, Gene Feder
BACKGROUND: Domestic violence and abuse (DVA) and child safeguarding are interlinked problems, impacting on all family members. Documenting in electronic patient records (EPRs) is an important part of managing these families. Current evidence and guidance, however, treats DVA and child safeguarding separately. This does not reflect the complexity clinicians face when documenting both issues in one family. AIM: To explore how and why general practice clinicians document DVA in families with children...
January 30, 2017: British Journal of General Practice: the Journal of the Royal College of General Practitioners
https://www.readbyqxmd.com/read/28125464/cardiac-output-assessment-in-patients-supported-with-left-ventricular-assist-device-discordance-between-thermodilution-and-indirect-fick-cardiac-output-measurements
#19
David M Tehrani, Jonathan Grinstein, Sara Kalantari, Gene Kim, Nitasha Sarswat, Sirtaz Adatya, Gabriel Sayer, Nir Uriel
Cardiac output (CO) assessed by thermodilution (TD) and indirect Fick (iFK) methods is commonly employed in Left Ventricular Assist Devices (LVAD) patients, however no study has assessed agreement. This study assess correlation between these methods, and association with hemodynamic/echocardiographic data in LVAD patients. Discordance was defined as a 20% difference between TD and iFK CO measurements. Bias and agreement were determined via the Bland-Altman technique in both the overall sample and iFK stratified tertiles...
January 23, 2017: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/28120698/short-course-daptomycin-lock-and-systemic-therapy-for-catheter-related-bloodstream-infections-a-retrospective-cohort-study-in-cancer-patients-with-surgically-implanted-devices
#20
Matteo Vassallo, Pierre-Luc Genillier, Brigitte Dunais, Regis Kaphan, Laurence Saudes, Yannick Duval, Fabien Rolland, Valerie Jullien, Nicolas Weiss, Elea Blanchouin, Annick Boscagli, Christophe Perrin, Nathalie Montagne
PURPOSE: Few in vivo studies have been reported describing efficacy and duration of antibiotic lock therapy (ALT) with daptomycin (DPT) for long-term catheter-related bloodstream infections (CRBSI) due to coagulase-negative staphylococci (CoNS). We retrospectively analysed the efficacy of short-course ALT with DPT in combination with systemic treatment (ST) for CoNS-associated CRBSI in our hospital. METHODS: Patients admitted for CoNS-associated CRBSI and treated with DPT as ALT and ST were retrospectively analysed...
January 25, 2017: Journal of Chemotherapy
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