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Vigyan V Bang, Michael S Levy
Exposure to ionizing radiation in cardiovascular imaging and its adverse impact on health is a growing concern. Cath lab imaging dose-reduction technology is an effective way to reduce patient and operator radiation dose. More clinical trials and studies such as this one are needed to assess the short-and long-term impact of this important technology.
June 2018: Catheterization and Cardiovascular Interventions
András Micsonai, Frank Wien, Éva Bulyáki, Judit Kun, Éva Moussong, Young-Ho Lee, Yuji Goto, Matthieu Réfrégiers, József Kardos
Circular dichroism (CD) spectroscopy is a widely used method to study the protein secondary structure. However, for decades, the general opinion was that the correct estimation of β-sheet content is challenging because of the large spectral and structural diversity of β-sheets. Recently, we showed that the orientation and twisting of β-sheets account for the observed spectral diversity, and developed a new method to estimate accurately the secondary structure (PNAS, 112, E3095). BeStSel web server provides the Beta Structure Selection method to analyze the CD spectra recorded by conventional or synchrotron radiation CD equipment...
June 11, 2018: Nucleic Acids Research
Brenda Happell, Brett Scholz, Sarah Gordon, Julia Bocking, Pete Ellis, Cath Roper, Jackie Liggins, Chris Platania-Phung
INTRODUCTION: Australia and New Zealand mental health policy requires consumer participation in all aspects of mental health services. Systemic participation informs and improves the quality of mental health services. Collaboration with consumer researchers should be similarly required. Enhanced understandings of collaborations are needed. AIM: To enhance understanding of the perspectives and experiences of nonconsumer researchers in working collaboratively with consumers as researchers...
June 12, 2018: Journal of Psychiatric and Mental Health Nursing
Felicity Mayer, Debra Bick, Cath Taylor
BACKGROUND: Cardiac disease is associated with adverse outcomes in pregnancy and is the leading cause of indirect maternal death in the United Kingdom (UK) and internationally. National and international guidelines recommend women should receive care from multidisciplinary teams; however evidence is lacking to inform how they should be operationalised. OBJECTIVES: To describe the composition and processes of multidisciplinary care between maternity and cardiac services before, during and after pregnancy for women with cardiac disease, and explore clinicians' (cardiologists, obstetricians, nurses, midwives) and women's experiences of delivering/receiving care within these models...
May 22, 2018: International Journal of Nursing Studies
Tryntsje Cuperus, Marina D Kraaij, Aldert L Zomer, Albert van Dijk, Henk P Haagsman
Host Defense Peptides (HDPs) such as cathelicidins are multifunctional effectors of the innate immune system with both antimicrobial and pleiotropic immunomodulatory functions. Chicken cathelicidin-2 (CATH-2) has multiple immunomodulatory effects in vitro and the D-amino acid analog of this peptide has been shown to partially protect young chicks from a bacterial infection. However, the mechanisms responsible for CATH-2 mediated in vivo protection have not been investigated so far. In this study, D-CATH-2 was administered in ovo and the immune status and microbiota of the chicks were investigated at 7 days posthatch to elucidate the in vivo mechanisms of the peptide...
2018: PloS One
Xialin Zuo, Qinghua Hou, Jizi Jin, Xiaohui Chen, Lixuan Zhan, Yanyan Tang, Zhe Shi, Weiwen Sun, En Xu
Stroke is the leading cause of adult disability in the world. In general, recovery from stroke is incomplete. Accumulating evidences have shown that focal cerebral infarction leads to dynamic trans-neuronal degeneration in non-ischemic remote brain regions, with the disruption of connections to synapsed neurons sustaining ischemic insults. Previously, we had reported that the ipsilateral striatum, thalamus degenerated in succession after permanent distal branch of middle cerebral artery occlusion (dMCAO) in Sprague-Dawley (SD) rats and cathepsin (Cath) B was activated before these relay degeneration...
2018: Frontiers in Aging Neuroscience
Tom P Thompson, Lynne Callaghan, Emma Hazeldine, Cath Quinn, Samantha Walker, Richard Byng, Gary Wallace, Siobhan Creanor, Colin Green, Annie Hawton, Jill Annison, Julia Sinclair, Jane Senior, Adrian H Taylor
INTRODUCTION: People with experience of the criminal justice system typically have worse physical and mental health, lower levels of mental well-being and have less healthy lifestyles than the general population. Health trainers have worked with offenders in the community to provide support for lifestyle change, enhance mental well-being and signpost to appropriate services. There has been no rigorous evaluation of the effectiveness and cost-effectiveness of providing such community support...
June 4, 2018: BMJ Open
Flannery C Dolan, Tzahi Y Cath, Terri S Hogue
The Colorado Water Plan estimates as much as 0.8 million irrigated acres may dry up statewide from agricultural to municipal and industrial transfers. To help mitigate this loss, new sources of water are being explored in Colorado. One such source may be produced water. Oil and gas production in 2016 alone produced over 300 million barrels of produced water. Currently, the most common method of disposal of produced water is deep well injection, which is costly and has been shown to cause induced seismicity...
June 1, 2018: Science of the Total Environment
Willemijn D Scholten, Neeltje M Batelaan, Patricia van Oppen, Johannes H Smit, Adriaan W Hoogendoorn, Harold J G M van Megen, Daniëlle C Cath, Anton J L M van Balkom
No abstract text is available yet for this article.
June 1, 2018: Psychotherapy and Psychosomatics
Stephanie M Riley, Danika C Ahoor, Tzahi Y Cath
Large volumes of water are required for the development of unconventional oil and gas (O&G) wells. Water scarcity coupled with seismicity induced by deep-well disposal promote new O&G wastewater management strategies, specifically treatment and reuse. One technology that has been proven effective for removal of organic matter and solids is biologically active filtration (BAF) with granular active carbon (GAC); however, further optimization is needed to enhance BAF performance. This study evaluated three GAC media (one spent and two new) and two nutrient-mix supplements for enhanced removal of chemical oxygen demand (COD) and dissolved organic carbon (DOC)...
May 31, 2018: Science of the Total Environment
Jane Scott, Jim Stewart
No abstract text is available yet for this article.
July 2018: Heart, Lung & Circulation
Brenda Happell, Sarah Gordon, Julia Bocking, Pete Ellis, Cath Roper, Jackie Liggins, Brett Scholz, Chris Platania-Phung
A crucial development resulting from consumer involvement in mental health services has been engagement as active participants in mental health research, often conducted in collaboration with mental health researchers representing the health disciplines (referred to in this paper as 'other' researchers). Despite progress in mental health consumer research, unequal power relations continue to pose a major barrier. Although power issues are discussed in the literature, there is little research from the perspective of other mental health researchers who have collaborated with consumers on research projects...
May 30, 2018: Issues in Mental Health Nursing
Michela Furlan, Umberto Rosani, Stefano Gambato, Paola Irato, Amedeo Manfrin, Mario Mardirossian, Paola Venier, Alberto Pallavicini, Marco Scocchi
Cathelicidins are an important family of antimicrobial peptide effectors of innate immunity in vertebrates. Two members of this group, CATH-1 and CATH-2, have been identified and characterized in teleosts (ray-finned fish). In this study, we investigated the expression of these genes in different tissues of rainbow trout challenged with 4 different inactivated pathogens. By using qPCR, we detected a strong induction of both cath-1 and cath-2 genes within 24 hours after intraperitoneal inoculation with Lactococcus garvieae, Yersinia ruckeri, Aeromonas salmonicida, or Flavobacterium psychrophilum cells...
May 28, 2018: Journal of Peptide Science: An Official Publication of the European Peptide Society
Senthilnathan Rajendran, Arunachalam Jothi
The Three-dimensional structure of a protein depends on the interaction between their amino acid residues. These interactions are in turn influenced by various biophysical properties of the amino acids. There are several examples of proteins that share the same fold but are very dissimilar at the sequence level. For proteins to share a common fold some crucial interactions should be maintained despite insignificant sequence similarity. Since the interactions are because of the biophysical properties of the amino acids, we should be able to detect descriptive patterns for folds at such a property level...
May 16, 2018: Computational Biology and Chemistry
Kamran Siddiqi, Rumana Huque, Mona Kanaan, Farid Ahmed, Tarana Ferdous, Sarwat Shah, Cath Jackson, Steve Parrott, Jasjit S Ahluwalia, Aziz Sheikh
Introduction: Children exposed to second-hand smoke (SHS) are at increased risk of respiratory illnesses. We piloted a Smoke Free Intervention (SFI) and trial methods before investigating its effectiveness and cost-effectiveness in primary school children. Methods: In a pilot cluster randomised controlled-trial in Bangladesh, primary schools were allocated to usual education (control) or SFI, using minimisation. Year-5 children were recruited. Masking treatment allocation was not possible...
May 16, 2018: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
K Pasha, H R Khan, A A Sumon
A successful cardiac catheterization Laboratory radiation safety program must manage patient and staff safety by reducing exposure to ionizing radiation to a level that is as low as reasonably achievable (ALARA). The first step in radiation safety is to avoid unnecessary use of ionizing radiation by justification of exposure, one of the basic principles of radiation protection. All individuals involved in fluoroscopic imaging procedures should familiarize themselves to the measures to protect themselves from exposure to unsafe doses of ionizing radiation...
April 2018: Mymensingh Medical Journal: MMJ
Anders L Thorsen, Stella J de Wit, Froukje E de Vries, Danielle C Cath, Dick J Veltman, Ysbrand D van der Werf, David Mataix-Cols, Bjarne Hansen, Gerd Kvale, Odile A van den Heuvel
BACKGROUND: Functional neuroimaging endophenotypes of obsessive-compulsive disorder (OCD) have been suggested during executive tasks. The purpose of this study was to investigate whether behavioral and neural responses during emotion processing and regulation also represent an endophenotype of OCD. METHODS: Forty-three unmedicated adult OCD patients, 19 of their unaffected siblings, and 38 healthy control participants underwent 3T functional magnetic resonance imaging during an emotion regulation task including neutral, fear-inducing, and OCD-related visual stimuli...
March 24, 2018: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
Ryan Callahan, James E Lock, Pinak B Shah, Audrey C Marshall
This study assesses the characteristics of coronary obstructions that underwent transcatheter intervention in a pediatric catheterization laboratory, the procedural details, and patient outcomes. Acute cardiac failure due to coronary obstructions in children is rare. The role of catheter based intervention is largely unreported. Single center retrospective review between January 2000 and December 2016. Thirty-three patients (median age 2y/o [0-38], weighing 9.6 kg [2.2-91]) underwent 39 transcatheter interventions on 39 lesions, mainly left main coronary (16/39; 39%) and right coronary (9/39; 23%) arteries...
May 9, 2018: Pediatric Cardiology
Dominika Zoltowska, Jagadeesh Kalavakunta
Totally implantable venous access ports are valuable invention for oncological patients. Erroneous arterial malposition rate is estimated from 1.1% to 3.7% (Bowen et al. Am. J. Surg., 2014, 208, 937). Early recognition and management are crucial to prevent further complications.
May 2018: Clinical Case Reports
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