Read by QxMD icon Read

Dong-Chan Oh Korea

Jung-Hyo Cho, Dal-Seok Oh, Sang-Hoon Hong, Heung Ko, Nam-Hun Lee, Sang-Eun Park, Chang-Woo Han, Seung-Mo Kim, Young-Chul Kim, Kang-San Kim, Chang-Won Choi, Seon-My Shin, Ki-Tae Kim, Hong-Sik Choi, Jang-Hoon Lee, Jun-Young Kim, Ji-Young Kang, Dong-Soo Lee, Yo-Chan Ahn, Chang-Gue Son
Discrepant incidence has been reported regarding the incidence of herb-induced liver injury (HILI). To address the growing worldwide concern of HILI, we evaluated the risk of HILI in a nationwide prospective study. Between April 2013 and January 2016, 1001 inpatients (360 males and 641 females) from 10 tertiary hospitals throughout South Korea were treated with herbal drugs and had their liver enzymes periodically measured. A total of six patients met the criteria for HILI with RUCAM scores ranging from 4 to 7...
June 20, 2017: Archives of Toxicology
Sang Eun Lee, Hae-Young Lee, Hyun-Jai Cho, Won-Seok Choe, Hokon Kim, Jin Oh Choi, Eun-Seok Jeon, Min-Seok Kim, Jae-Joong Kim, Kyung-Kuk Hwang, Shung Chull Chae, Sang Hong Baek, Seok-Min Kang, Dong-Ju Choi, Byung-Su Yoo, Kye Hun Kim, Hyun-Young Park, Myeong-Chan Cho, Byung-Hee Oh
BACKGROUND AND OBJECTIVES: The burden of heart failure has increased in Korea. This registry aims to evaluate demographics, clinical characteristics, management, and long-term outcomes in patients hospitalized for acute heart failure (AHF). SUBJECTS AND METHODS: We prospectively enrolled a total of 5625 consecutive subjects hospitalized for AHF in one of 10 tertiary university hospitals from March 2011 to February 2014. Descriptive statistics were used to determine the baseline characteristics of the study population and to compare them with those from other registries...
May 2017: Korean Circulation Journal
Jin Young Ahn, Hea Won Ann, Yongduk Jeon, Mi Young Ahn, Dong Hyun Oh, Yong Chan Kim, Eun Jin Kim, Je Eun Song, In Young Jung, Moo Hyun Kim, Wooyoung Jeong, Nam Su Ku, Su Jin Jeong, Jun Yong Choi, Dongeun Yong, Young Goo Song, June Myung Kim
BACKGROUND: The incidence of Proteus mirabilis antimicrobial resistance, especially that mediated by extended-spectrum β-lactamases (ESBLs), has increased. We investigated the impact of ESBL production on the mortality of patients with P. mirabilis bacteremia in Korea. METHODS: Patients diagnosed with P. mirabilis bacteremia between November 2005 and December 2013 at a 2000-bed tertiary care center in South Korea were included in this study. Phenotypic and molecular analyses were performed to assess ESBL expression...
May 3, 2017: BMC Infectious Diseases
Mi Young Ahn, Joel O Wertheim, Woo Joo Kim, Shin-Woo Kim, Jin Soo Lee, Hea Won Ann, Yongduk Jeon, Jin Young Ahn, Je Eun Song, Dong Hyun Oh, Yong Chan Kim, Eun Jin Kim, In Young Jung, Moo Hyun Kim, Wooyoung Jeong, Su Jin Jeong, Nam Su Ku, June Myung Kim, Davey M Smith, Jun Yong Choi
Molecular epidemiology can help clarify the properties and dynamics of HIV-1 transmission networks in both global and regional scales. We studied 143 HIV-1-infected individuals recruited from four medical centers of three cities in South Korea between April 2013 and May 2014. HIV-1 env V3 sequence data were generated (337-793 bp) and analyzed using a pairwise distance-based clustering approach to infer putative transmission networks. Participants whose viruses were ≤2.0% divergent according to Tamura-Nei 93 genetic distance were defined as clustering...
August 2017: AIDS Research and Human Retroviruses
Munhyung Bae, So Hyun Park, Yun Kwon, Sang Kook Lee, Jongheon Shin, Joo-Won Nam, Dong-Chan Oh
Based on profiles of secondary metabolites produced by marine bacteria obtained using LC/MS, succinilenes A-D (1-4), new triene polyols, were discovered from a culture of a Streptomyces strain SAK1, which was collected in the southern area of Jeju Island, Republic of Korea. The gross structures of 1-4 were primarily determined through analysis of NMR spectra. The double bond geometries of the succinilenes, which could not be established from conventional ¹H NMR spectra because of the highly overlapped olefinic signals, were successfully deciphered using the recently developed quantum-mechanics-driven ¹H iterative full spin analysis (QM-HiFSA)...
February 14, 2017: Marine Drugs
SeonJu Park, Nanyoung Kim, Guijae Yoo, Sang-Nam Kim, Hyun-Jung Kwon, Kiwon Jung, Dong-Chan Oh, Yun-Hee Lee, Seung Hyun Kim
Juglans mandshurica Maxim. (Juglandaceae) is a traditional folk medicine used for treatment of dermatosis and to relieve aches in Korea and China. In this study, eight compounds, along with six known compounds, were isolated from the fruit of J. mandshurica. Among the six known compounds, the absolute configuration of two compounds were determined. The structures of compounds were determined on the basis of extensive spectroscopic methods, including 1D and 2D NMR and CD spectroscopic data. All isolated compounds were tested for their lipolytic activities in differentiated adipocytes using C3H10T1/2 mouse embryonic fibroblasts...
May 2017: Phytochemistry
In Young Jung, Young Goo Song, Jun Yong Choi, Moo Hyun Kim, Woo Yong Jeong, Dong Hyun Oh, Yong Chan Kim, Je Eun Song, Eun Jin Kim, Ji Un Lee, Su Jin Jeong, Nam Su Ku, June Myung Kim
BACKGROUND: In areas where Mycobacterium tuberculosis is endemic, tuberculosis is known to be the most common cause of pericarditis. However, the difficulty in diagnosis may lead to late complications such as constrictive pericarditis and increased mortality. Therefore, identification of patients at a high risk for poor prognosis, and prompt initiation of treatment are important in the outcome of TB pericarditis. The aim of this study is to identify the predictive factors for unfavorable outcomes of TB pericarditis in HIV-uninfected persons in an intermediate tuberculosis burden country...
November 29, 2016: BMC Infectious Diseases
Ju Han Kim, Shung-Chull Chae, Dong Joo Oh, Hyo-Soo Kim, Young Jo Kim, Youngkeun Ahn, Myeong Chan Cho, Chong Jin Kim, Jung-Han Yoon, Hyun-Young Park, Myung Ho Jeong
BACKGROUND: The Korea Acute Myocardial Infarction Registry (KAMIR)-National Institutes of Health (NIH) registry has the aim of evaluating the clinical characteristics, management, and long-term outcomes of patients with acute myocardial infarction (AMI) in Korea. METHODS AND RESULTS: Patients hospitalized for AMI in 20 tertiary university hospitals in Korea have been enrolled since November 2011. The study is expected to complete the scheduled enrollment of approximately 13,000 patients in October 2015, and follow-up duration is up to 5 years for each patient...
May 25, 2016: Circulation Journal: Official Journal of the Japanese Circulation Society
Yu Kyung Cho, Jeong Seop Moon, Dong Su Han, Yong Chan Lee, Yeol Kim, Bo Young Park, Il-Kwun Chung, Jin-Oh Kim, Jong Pil Im, Jae Myung Cha, Hyun Gun Kim, Sang Kil Lee, Hang Lak Lee, Jae Young Jang, Eun Sun Kim, Yunho Jung, Chang Mo Moon
BACKGROUND/AIMS: In Korea, the nationwide gastric cancer screening program recommends biennial screening for individuals aged 40 years or older by way of either an upper gastrointestinal series or endoscopy. The national endoscopic quality assessment (QA) program began recommending endoscopy in medical institutions in 2009. We aimed to assess the effect, burden, and cost of the QA program from the viewpoint of medical institutions. METHODS: We surveyed the staff of institutional endoscopic units via e-mail...
November 2016: Clinical Endoscopy
Munhyung Bae, Kyuho Moon, Jihye Kim, Hyen Joo Park, Sang Kook Lee, Jongheon Shin, Dong-Chan Oh
Mohangic acids A-E (1-5) were isolated from a marine Streptomyces sp. collected from a mudflat in Buan, Republic of Korea. Comprehensive spectroscopic analysis revealed that the mohangic acids are new members of the p-aminoacetophenonic acid class. The relative and absolute configurations of the mohangic acids were determined by J-based configuration analysis and by the application of bidentate chiral NMR solvents followed by (13)C NMR analysis, chemical derivatization, and circular dichroism spectroscopy. Mohangic acid E (5), which is the first glycosylated compound in the p-aminoacetophenonic acid family, displayed significant quinone reductase induction activity...
February 26, 2016: Journal of Natural Products
Kwangzoo Chung, Youngyih Han, Jinsung Kim, Sung Hwan Ahn, Sang Gyu Ju, Sang Hoon Jung, Yoonsun Chung, Sungkoo Cho, Kwanghyun Jo, Eun Hyuk Shin, Chae-Seon Hong, Jung Suk Shin, Seyjoon Park, Dae-Hyun Kim, Hye Young Kim, Boram Lee, Gantaro Shibagaki, Hideki Nonaka, Kenzo Sasai, Yukio Koyabu, Changhoon Choi, Seung Jae Huh, Yong Chan Ahn, Hong Ryull Pyo, Do Hoon Lim, Hee Chul Park, Won Park, Dong Ryul Oh, Jae Myung Noh, Jeong Il Yu, Sanghyuk Song, Ji Eun Lee, Bomi Lee, Doo Ho Choi
PURPOSE: The purpose of this report is to describe the proton therapy system at Samsung Medical Center (SMC-PTS) including the proton beam generator, irradiation system, patient positioning system, patient position verification system, respiratory gating system, and operating and safety control system, and review the current status of the SMC-PTS. MATERIALS AND METHODS: The SMC-PTS has a cyclotron (230 MeV) and two treatment rooms: one treatment room is equipped with a multi-purpose nozzle and the other treatment room is equipped with a dedicated pencil beam scanning nozzle...
December 2015: Radiation Oncology Journal
Hyun Soo Lee, Kee Suck Suh, Dong-Youn Lee, Kwang Hyun Cho, Sang Ho Oh, Soo-Chan Kim, Seok-Jong Lee, Dong Hoon Shin, Tae Young Yoon, Young Ho Won, You Chan Kim
The epidemiological and clinicopathological features of cutaneous lymphoma may vary by geographical area. However, only a few large-scale epidemiological studies of cutaneous lymphoma have been performed, mainly in the USA and Europe. This aim of this study was to determine the recent characteristics of cutaneous lymphoma in Korea according to the WHO/EORTC classification. A total of 422 patients with newly diagnosed cutaneous lymphoma from January 2009 to December 2013 comprising 293 cases of mature T-cell and natural killer (NK)-cell lymphoma and 39 cases of mature B-cell lymphoma were retrospectively reviewed...
May 2016: Acta Dermato-venereologica
Min Cheol Kim, Jung Hwan Lee, Bora Shin, Lalita Subedi, Jin Wook Cha, Jin-Soo Park, Dong-Chan Oh, Sun Yeou Kim, Hak Cheol Kwon
Salinazinones A (1) and B (2), two unprecedented pyrrolidinyl-oxazinones, were isolated from the culture broth of Streptomyces sp. KMF-004 from a solar saltern at Aphae Island, Korea. The structures of these salinazinones, which are unusual and consist of 2-methylpropenyl-1,3-oxazin-6-one bearing 1-oxopyrrolidinyl substituents, were assigned by spectral and chemical analyses using Mosher's method, circular dichroism (CD), and calculated ECD. Salinazinones are the first examples of a natural alkaloid class composed of an oxazinone-pyrrolidone conjugate...
October 16, 2015: Organic Letters
Si-Hyuck Kang, Jin Joo Park, Dong-Ju Choi, Chang-Hwan Yoon, Il-Young Oh, Seok-Min Kang, Byung-Su Yoo, Eun-Seok Jeon, Jae-Joong Kim, Myeong-Chan Cho, Shung Chull Chae, Kyu-Hyung Ryu, Byung-Hee Oh
OBJECTIVE: Plasma level of N-terminal-pro-brain natriuretic peptide (NT-proBNP) is a reliable prognostic factor in patients with heart failure (HF). However, it is unclear how differently the biomarker predicts adverse outcomes in HF with preserved EF (HFpEF) versus HF with reduced EF (HFrEF). METHODS: From the Korean Heart Failure registry, a prospective multicentre cohort for consecutive patients who were hospitalised for acute HF syndrome, those with available NT-proBNP and LVEF measurements were extracted...
December 2015: Heart: Official Journal of the British Cardiac Society
Munhyung Bae, Beomkoo Chung, Ki-Bong Oh, Jongheon Shin, Dong-Chan Oh
Alterations in microbial culture conditions may trigger the production of diverse bioactive secondary metabolites. While applying various culture conditions and monitoring secondary metabolite profiles using LC/MS, hormaomycins B and C (1 and 2) were discovered from a marine mudflat-derived actinomycete, Streptomyces sp., collected in Mohang, Korea. The planar structures of the hormaomycins, which bear structurally-unique units, such as 4-(Z)-propenylproline, 3-(2-nitrocyclopropyl)alanine, 5-chloro-1-hydroxypyrrol-2-carboxylic acid and b-methylphenylalanine, were established as the first natural analogues belonging to the hormaomycin peptide class...
August 2015: Marine Drugs
Keum Ji Jung, Yangsoo Jang, Dong Joo Oh, Byung-Hee Oh, Sang Hoon Lee, Seong-Wook Park, Ki-Bae Seung, Hong-Kyu Kim, Young Duk Yun, Sung Hee Choi, Jidong Sung, Tae-Yong Lee, Sung Hi Kim, Sang Baek Koh, Moon Chan Kim, Hyeon Chang Kim, Heejin Kimm, Chungmo Nam, Sungha Park, Sun Ha Jee
BACKGROUND AND AIMS: To evaluate the performance of the American College of Cardiology/American Heart Association (ACC/AHA) 2013 Pooled Cohort Equations in the Korean Heart Study (KHS) population and to develop a Korean Risk Prediction Model (KRPM) for atherosclerotic cardiovascular disease (ASCVD) events. METHODS: The KHS cohort included 200,010 Korean adults aged 40-79 years who were free from ASCVD at baseline. Discrimination, calibration, and recalibration of the ACC/AHA Equations in predicting 10-year ASCVD risk in the KHS cohort were evaluated...
September 2015: Atherosclerosis
Sung Eun Kim, Chan Woong Kim, Sang Jin Lee, Je Hyeok Oh, Dong Hoon Lee, Tae Ho Lim, Hyuk Joong Choi, Hyun Soo Chung, Ji Yeong Ryu, Hye Young Jang, Yoon Hee Choi, Su Jin Kim, Jin Hee Jung
OBJECTIVES: Although human factors are important in terms of patient safety, there have been very few reports on the attitudes of healthcare professionals working in acute care settings in South Korea. In the present study, we investigated the attitudes of such professionals, their cultures and their management systems. DESIGN: A questionnaire survey with 65 items covering nine themes affecting patient safety. Nine themes were compared via a three-or-more-way analysis of variance, with interaction, followed by multiple comparisons among several groups...
2015: BMJ Open
Myoung Shin Kim, Jae Kyung Kim, Mi Woo Lee, Kee-Chan Moon, Beom Joon Kim, Sang Wook Son, Hyo Hyun Ahn, Sang Ho Oh, Hee Joon Yu, Dong Youn Lee, Kwang Hyun Cho, Baik Kee Cho, Moon Bum Kim, Kee Suck Suh, You Chan Kim, Byung In Ro, Joon Soo Park, Jong Soo Choi, Jee Bum Lee
Deep cutaneous fungal infections (DCFI) occur worldwide and their prevalence is influenced by personal factors of the affected patients and the geographic and cultural features. Surveillance studies of DCFI with respect to the various clinical backgrounds of affected patients can ultimately help to improve their outcome. Expanding on our previous study, we performed a retrospective analysis of patients with DCFI who were treated in a group of university teaching hospitals in Korea to determine the trends within a 5-year period...
October 2015: Journal of Dermatology
Jin Joo Park, Dong-Ju Choi, Chang-Hwan Yoon, Il-Young Oh, Ju Hyun Lee, Soyeon Ahn, Byung-Su Yoo, Seok-Min Kang, Jae-Joong Kim, Sang-Hong Baek, Myeong-Chan Cho, Eun-Seok Jeon, Shung Chull Chae, Kyu-Hyung Ryu, Byung-Hee Oh
AIMS: In acute heart failure (AHF) patients, pulmonary oedema and low tissue perfusion may lead to changes in the acid-base balance, which may be associated with worse outcomes. METHODS AND RESULTS: In this prospective nationwide cohort study from 24 academic hospitals, arterial blood gas (ABG) was measured in 1982 AHF patients at hospital admission. Acidosis was defined as pH <7.36, and alkalosis as pH >7.44. Mortality was stratified according to ABG results...
June 2015: European Journal of Heart Failure
Tae Hyung Won, Chang-Kwon Kim, So-Hyoung Lee, Boon Jo Rho, Sang Kook Lee, Dong-Chan Oh, Ki-Bong Oh, Jongheon Shin
Four new iodobenzene-containing dipeptides (1-4), a related bromotryptophan-containing dipeptide (5), and an iodophenethylamine (6) were isolated from the ascidian Aplidium sp. collected off the coast of Chuja-do, Korea. The structures of these novel compounds, designated as apliamides A-E (1-5) and apliamine A (6) were determined via combined spectroscopic analyses. The absolute configuration of the amino acid residue in 1 was determined by advanced Marfey's analysis. Several of these compounds exhibited moderate cytotoxicity and significant inhibition against Na+/K+-ATPase (4)...
June 2015: Marine Drugs
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"