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Desflurane vs sevoflurane

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https://www.readbyqxmd.com/read/29509579/does-equi-minimum-alveolar-concentration-value-ensure-equivalent-analgesic-or-hypnotic-potency-a-comparison-between-desflurane-and-sevoflurane
#1
Kyoung-Ho Ryu, Keulame Song, Tae-Young Lim, Won-Jun Choi, Yun-Hong Kim, Hyun-Soo Kim
BACKGROUND: Minimum alveolar concentration (MAC) has traditionally been used to compare the potency of volatile anesthetics. However, as it reflects the spinal mechanism of immobility rather than the cerebral mechanism of analgesia and hypnosis, it is doubtful that equi-MAC connotes equivalent analgesic or hypnotic potency. The level of analgesia and hypnosis can be assessed using surgical pleth index and bispectral index (BIS) values, respectively. This study was designed to compare the surgical pleth index and BIS values produced by equi-MAC of desflurane and sevoflurane in patients undergoing single-agent volatile anesthesia...
June 2018: Anesthesiology
https://www.readbyqxmd.com/read/29452603/the-effects-of-desflurane-and-sevoflurane-on-nesfatin-1-levels-in-laparoscopic-cholecystectomy-a-randomized-controlled-trial
#2
A T D Ozcan, C B Altin, S Erdogan, M Ergin, A Çiftçi, H Kara, S M Aksoy, A But
BACKGROUND: Nesfatin-1 is involved in cardiovascular regulation, stress-related responses. The objective of this study is to investigate the impact of volatile anesthetics on Nesfatin-1 levels. METHOD: Fourty-two patients aged 30-65 years with the American Society Anesthesiology (ASA) Class I-II who were scheduled for laparoscopic cholecystectomy were included in the study Patients were randomized into two group; desflurane administered group (Group I, n = 21) and sevoflurane administered group (Group II, n = 21)...
February 16, 2018: BMC Anesthesiology
https://www.readbyqxmd.com/read/29239148/effects-of-closed-loop-intravenous-anesthesia-guided-by-the-bispectral-index-in-adult-patients-on-emergence-delirium-a-randomized-controlled-study
#3
Antonella Cotoia, Lucia Mirabella, Renata Beck, Pompeo Matrella, Valentina Assenzo, Thierry Chazot, Gilda Cinnella, Ngai Liu, Michele Dambrosio
BACKGROUND: Emergence delirium (ED) is an acute change in cognition after general anesthesia (GA) occurring in operative room, recovery room or in postanesthesia care. The automated propofolremifentanil titration by Bispectral index (BIS) (AutoTIVA) avoids period of deep (BIS<40) anesthesia and could potentially decrease the ED. The aim of this study was to evaluate ED in surgical patients under AutoTIVA, manual titration of propofol-remifentanil (ManualTIVA) or volatile BIS-guided GA...
December 13, 2017: Minerva Anestesiologica
https://www.readbyqxmd.com/read/29094751/evaluation-of-a-novel-waste-anaesthetic-gas-scavenger-device-for-use-during-recovery-from-anaesthesia
#4
R Tallent, J Corcoran, J Sebastian
Volatile anaesthetic agents are a potential occupational health hazard to theatre and recovery staff. Operating theatres and anaesthetic rooms are required to be equipped with scavenging systems, but recovery units often are not. We compared exhaled, spectrophotometric sevoflurane and desflurane concentrations 15 cm from the mouth ('patient breathing zone') and 91 cm laterally to the patient ('nurse work zone') in 120 patients after tracheal extubation who were consecutively allocated to either ISO-Gard mask oxygen/scavenging or standard oxygen mask, 0 min, 10 min and 20 min after arrival in the theatre recovery unit...
January 2018: Anaesthesia
https://www.readbyqxmd.com/read/29080558/isoflurane-and-postoperative-respiratory-depression-following-laparoscopic-surgery-a-retrospective-propensity-matched-analysis
#5
Alexandre N Cavalcante, Carmelina Gurrieri, Juraj Sprung, Darrell R Schroeder, Toby N Weingarten
Episodes of respiratory depression during the immediate postoperative recovery period (Phase I post-anesthesia recovery) have been associated with respiratory complications during Phase II recovery. Using multivariable analyses in several surgical cohorts, we previously identified potential associations between patient and perioperative factors and increased risk for Phase I respiratory depression. The aim of this study is to use the propensity-matched analysis to specifically assess for a potential association between the use of isoflurane and episodes of Phase I respiratory depression after laparoscopic operations...
February 20, 2018: Bosnian Journal of Basic Medical Sciences
https://www.readbyqxmd.com/read/28924371/comparison-of-the-analgesic-properties-of-sevoflurane-and-desflurane-using-surgical-pleth-index-at-equi-minimum-alveolar-concentration
#6
Kyoungho Ryu, Keulame Song, Jia Kim, Eugene Kim, Seong-Hyop Kim
Background: Traditionally, minimum alveolar concentration (MAC) has been used as the standard measure to compare the potencies of volatile anesthetics. However, it reflects the spinal mechanism of immobility rather than the subcortical mechanism of analgesia. Recently, the surgical pleth index (SPI) derived from photoplethysmographic waveform was shown to reflect the intraoperative analgesic component. This study was designed to compare the SPI values produced by equi-MAC of two commonly used volatile anesthetics, sevoflurane and desflurane...
2017: International Journal of Medical Sciences
https://www.readbyqxmd.com/read/28858134/desflurane-versus-sevoflurane-in-pediatric-anesthesia-with-a-laryngeal-mask-airway-a-randomized-controlled-trial
#7
RANDOMIZED CONTROLLED TRIAL
Eun-Hee Kim, In-Kyung Song, Ji-Hyun Lee, Hee-Soo Kim, Hyun-Chang Kim, Soo-Hyuk Yoon, Young-Eun Jang, Jin-Tae Kim
BACKGROUND: Desflurane with a laryngeal mask airway may have advantages during ambulatory anesthesia. However, desflurane-induced airway irritability makes the use of desflurane challenging, especially in children. This study compared desflurane with sevoflurane maintenance anesthesia in terms of respiratory events and the emergence characteristics in children with a laryngeal mask airway. METHODS: This randomized controlled trial evaluated 200 children undergoing strabismus surgery allocated to desflurane or sevoflurane groups...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28791477/electroencephalographic-effect-of-age-adjusted-1-mac-desflurane-and-sevoflurane-in-young-middle-aged-and-elderly-patients
#8
Shinya Kanazawa, Yutaka Oda, Chika Maeda, Ryu Okutani
PURPOSE: We examined the hypothesis that 1 minimum alveolar concentration (MAC) of desflurane and sevoflurane provides different depth of anesthesia. METHODS: One hundred and twenty young (20-30 years), middle-aged (31-65 years), and elderly (66-80 years) patients were randomly allocated to receive either desflurane or sevoflurane (n = 20, each group). General anesthesia was induced with propofol 2 mg/kg bolus and remifentanil 0.25 µg/kg/min, which was stopped after tracheal intubation...
October 2017: Journal of Anesthesia
https://www.readbyqxmd.com/read/28184263/a-low-dose-of-droperidol-decreases-the-desflurane-concentration-needed-during-breast-cancer-surgery-a-randomized-double-blinded-study
#9
Maiko Satomoto, Yushi U Adachi, Koshi Makita
BACKGROUND: Droperidol (DHB) reportedly reduces the dose of propofol needed to achieve hypnosis when anesthesia is induced and decreases the bispectral index (BIS) in propofol-sedated patients during spinal anesthesia. We reported previously that supplemental DHB decreased the BIS after the administration of sevoflurane and remifentanil. This study investigated the effect of DHB on desflurane (DES) consumption in a clinical setting. METHODS: We conducted a prospective, randomized double-blinded study of 35 women with American Society of Anesthesiologist physical status I or II who underwent a mastectomy...
February 2017: Korean Journal of Anesthesiology
https://www.readbyqxmd.com/read/27273061/postoperative-environmental-anesthetic-vapour-concentrations-following-removal-of-the-airway-device-in-the-operating-room-versus-the-postanesthesia-care-unit
#10
COMPARATIVE STUDY
Sara K Cheung, Timur Özelsel, Saifee Rashiq, Ban C Tsui
PURPOSE: This study was designed to compare waste anesthetic gas (WAG) concentrations within patients' breathing zones after removal of the patient's airway device in the postanesthesia care unit (PACU) vs in the operating room (OR). METHODS: Following Research Ethics Board approval and patient consent, we recruited patients undergoing surgery who received volatile anesthesia via an endotracheal tube or supraglottic airway. Patients had their airway device removed in the OR or in the PACU depending on the attending anesthesiologist's preference...
September 2016: Canadian Journal of Anaesthesia, Journal Canadien D'anesthésie
https://www.readbyqxmd.com/read/26830645/the-effect-of-sevoflurane-versus-desflurane-on-postoperative-catheter-related-bladder-discomfort-in-patients-undergoing-transurethral-excision-of-a-bladder-tumour-a-randomized-controlled-trial
#11
RANDOMIZED CONTROLLED TRIAL
Hyun-Chang Kim, Won-Pyo Hong, Young-Jin Lim, Hee-Pyoung Park
PURPOSE: Catheter-related bladder discomfort (CRBD) due to an indwelling urinary catheter can cause postoperative distress, and the mechanism underlying CRBD is linked to the activation of muscarinic receptors. Inhalation of anesthetic agents, such as sevoflurane and desflurane, has differential inhibitory effects on muscarinic receptors. We aimed to compare the effect of intraoperative sevoflurane vs desflurane inhalation on postoperative CRBD. METHODS: Eighty-nine patients undergoing transurethral resection of a bladder tumour (TURBT) were randomly allocated to two groups...
May 2016: Canadian Journal of Anaesthesia, Journal Canadien D'anesthésie
https://www.readbyqxmd.com/read/26806956/the-influence-of-propofol-and-sevoflurane-on-intestinal-motility-during-laparoscopic-surgery
#12
RANDOMIZED CONTROLLED TRIAL
M Desmet, P Vander Cruyssen, H Pottel, S Carlier, D Devriendt, F Van Rooy, W De Corte
BACKGROUND: Volatile anaesthetics have an influence on small bowel peristalsis during laparoscopic surgery. A recent study concluded that desflurane increased intestinal motility compared to sevoflurane. Hence, a desflurane-based anaesthesia protocol may reduce surgical exposure during intestinal suturing or stapling due to small bowel hyperperistalsis. The effect of propofol on intestinal motility is not well studied. We tested the hypothesis that a propofol-remifentanil anaesthesia increases intestinal contractions in comparison with a sevoflurane-remifentanil anaesthesia...
March 2016: Acta Anaesthesiologica Scandinavica
https://www.readbyqxmd.com/read/26735317/economic-and-environmental-considerations-during-low-fresh-gas-flow-volatile-agent-administration-after-change-to-a-nonreactive-carbon-dioxide-absorbent
#13
Richard H Epstein, Franklin Dexter, David P Maguire, Niraj K Agarwalla, David M Gratch
BACKGROUND: Reducing fresh gas flow (FGF) during general anesthesia reduces costs by decreasing the consumption of volatile anesthetics and attenuates their contribution to greenhouse gas pollution of the environment. The sevoflurane FGF recommendations in the Food and Drug Administration package insert relate to concern over potential toxicity from accumulation in the breathing circuit of compound A, a by-product of the reaction of the volatile agent with legacy carbon dioxide absorbents containing strong alkali such as sodium or potassium hydroxide...
April 2016: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/26487303/effects-of-changing-from-sevoflurane-to-desflurane-on-the-recovery-profile-after-sevoflurane-induction-a-randomized-controlled-study
#14
RANDOMIZED CONTROLLED TRIAL
Ikuomi Mikuni, Shuto Harada, Ryuta Yakushiji, Hiroshi Iwasaki
PURPOSE: Desflurane has the lowest solubility of currently available volatile anesthetics and may allow for more rapid emergence and recovery compared with sevoflurane. Nevertheless, after volatile induction with sevoflurane, it has not been determined whether the use of desflurane provides faster emergence and recovery. The present study aimed to elucidate the effects of changing from sevoflurane to desflurane during the early part of anesthesia. METHODS: Fifty-two patients who were scheduled for vitreous surgery with general anesthesia were enrolled in this randomized controlled study...
March 2016: Canadian Journal of Anaesthesia, Journal Canadien D'anesthésie
https://www.readbyqxmd.com/read/26442399/desflurane-compared-to-sevoflurane-for-cirrhotic-patients-undergoing-major-liver-resection-a-randomized-control-study
#15
RANDOMIZED CONTROLLED TRIAL
M Abou Hussein, F Mahmoud, R Beltagy, A Hasanin, K Yassen, A Attar
BACKGROUND: Major liver resection is associated with haemodynamic, hepatic and renal changes as a result of the procedure. AIM: To compare Desflurane (D) versus Sevoflurane (S) on hepatic, renal functions, haemodynamics and perioperative course for cirrhotic patients undergoing major liver resection. PATIENTS AND METHODS: A prospective randomized control study with 50 patients (Child A) (D, n = 25 and S, n = 25). End tidal D or S adjusted with Entropy (40-60)...
June 2015: Middle East Journal of Anesthesiology
https://www.readbyqxmd.com/read/26427305/length-of-postanesthetic-care-unit-stay-in-elderly-patients-after-general-anesthesia-a-randomized-controlled-trial-comparing-desflurane-and-sevoflurane
#16
RANDOMIZED CONTROLLED TRIAL
Jatuporn Pakpirom, Jitsinee Kraithep, Ngamjit Pattaravit
OBJECTIVE: The purpose of this study was to compare the length of postanesthetic care unit (PACU) stay and recovery profiles of elderly patients after general anesthesia between sevoflurane and desflurane. DESIGN: Randomized, double-blind, controlled clinical trial. SETTING: Tertiary care hospital, university hospital. PATIENTS: Eighty elderly patients undergoing nonemergency surgery under general anesthesia. INTERVENTION: Patients were randomly allocated into 2 groups: sevoflurane group (n = 38) and desflurane group (n = 42) in a double-blind manner...
August 2016: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/26335917/sevoflurane-versus-desflurane-on-the-incidence-of-postreperfusion-syndrome-during-living-donor-liver-transplantation-a-randomized-controlled-trial
#17
RANDOMIZED CONTROLLED TRIAL
Jiwon Lee, Yong-Jae Yoo, Jung-Man Lee, Young Jae Park, Ho Geol Ryu
BACKGROUND: Various interventions to reduce postreperfusion syndrome during liver transplantation have been explored, but the effect of volatile anesthetics used during liver transplantation on the incidence of postreperfusion syndrome has not been evaluated. A randomized controlled trial was performed to compare the incidence of postreperfusion syndrome between 2 commonly used volatile anesthetics, sevoflurane and desflurane. METHODS: Sixty-two adult liver recipients scheduled for living-donor liver transplantation were randomized to receive either sevoflurane or desflurane for general anesthesia...
March 2016: Transplantation
https://www.readbyqxmd.com/read/26198766/desflurane-and-sevoflurane-use-during-low-and-minimal-flow-anesthesia-at-fixed-vaporizer-settings
#18
Maria Horwitz, Jan G Jakobsson
BACKGROUND: The pharmacokinetics for sevoflurane and desflurane makes them suitable for low-flow anesthesia. The aim of the present study was to assess the use of desflurane and sevoflurane at constant vaporizer settings and fixed low fresh gas flows. METHODS: One hundred ASA 1-2 patients undergoing elective laparoscopic surgery were randomized into 4 groups (25 patients each): a fixed fresh gas flow 1.0 or 0.5 L/min with desflurane (D1.0 and D0.5) or sevoflurane (S1...
February 2016: Minerva Anestesiologica
https://www.readbyqxmd.com/read/25882167/accuracy-of-calculated-volatile-agent-consumption-from-fresh-gas-content
#19
P Biro, O Kneschke, O M Theusinger
BACKGROUND: Case-by-case assessment of volatile anesthetic (VA) consumption is necessary to perform agent sparing dosing measures and for billing purposes. The gold standard technique for this purpose is to measure the weight difference of the vaporizer that occurs during VA delivery. Because suitable equipment is rarely available and weighing the vaporizer is only possible in prospectively planned fashion, a calculation method from recorded fresh gas flow (FGF) and VA courses is a viable alternative...
May 2015: Acta Anaesthesiologica Scandinavica
https://www.readbyqxmd.com/read/25829905/comparison-of-intraoperative-brain-condition-hemodynamics-and-postoperative-recovery-between-desflurane-and-sevoflurane-in-patients-undergoing-supratentorial-craniotomy
#20
Surya Kumar Dube, Mihir Prakash Pandia, Arvind Chaturvedi, Parmod Bithal, Hari Hara Dash
BACKGROUND: Post operative recovery has been reported to be faster with desflurane than sevoflurane anesthesia in previous studies. The use of desflurane is often criticized in neurosurgery due to the concerns of cerebral vasodilation and increase in ICP and studies comparing desflurane and sevoflurane in neurosurgey are scarce. So we compared the intraoperative brain condition, hemodynamics and postoperative recovery in patients undergoing elective supratentorial craniotomy receiving either desflurane or sevoflurane...
April 2015: Saudi Journal of Anaesthesia
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