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https://www.readbyqxmd.com/read/28531209/the-dynamics-of-a-mediterranean-coralligenous-sponge-assemblage-at-decennial-and-millennial-temporal-scales
#1
Marco Bertolino, Gabriele Costa, Mirko Carella, Riccardo Cattaneo-Vietti, Carlo Cerrano, Maurizio Pansini, Gianluca Quarta, Lucio Calcagnile, Giorgio Bavestrello
This paper concerns the changes occurred over both decennial and millennial spans of time in a sponge assemblage present in coralligenous biogenic build-ups growing at 15 m depth in the Ligurian Sea (Western Mediterranean). The comparison of the sponge diversity after a time interval of about 40 years (1973-2014) showed a significant reduction in species richness (about 45%). This decrease affected mainly the massive/erect sponges, and in particular the subclass Keratosa, with a species loss of 67%, while the encrusting and cavity dwelling sponges lost the 36% and 50%, respectively...
2017: PloS One
https://www.readbyqxmd.com/read/28530668/radioimmunotherapy-augmented-beam-chemotherapy-vs-beam-alone-as-the-high-dose-regimen-for-autologous-stem-cell-transplantation-asct-in-relapsed-follicular-lymphoma-fl-a-retrospective-study-of-the-ebmt-lymphoma-working-party
#2
L Bento, A Boumendil, H Finel, S Le Gouill, S Amorim, H Monjanel, R Bouabdallah, J O Bay, E Nicolas-Virelizier, G McQuaker, G Rossi, R Johnson, A Huynh, P Ceballos, A Rambaldi, E Bachy, R Malladi, K Orchard, D Pohlreich, H Tilly, F Bonifazi, X Poiré, F Guilhot, A Haenel, C Crawley, B Metzner, J Gribben, N H Russell, G Damaj, K Thomson, P Dreger, S Montoto
Relapse remains the most common cause of treatment failure in patients receiving autologous stem cell transplantation (ASCT) for follicular lymphoma (FL). The aim of this study was to evaluate the effect of adding radioimmunotherapy or rituximab (R) to BEAM (carmustine, etoposide, ara-c, melphalan) high-dose therapy for ASCT in patients with relapsed FL. Using the European Society for Blood and Marrow Transplantation registry, we conducted a cohort comparison of BEAM (n=1973), Zevalin-BEAM (Z-BEAM) (n=207) and R-BEAM (n=179) and also a matched-cohort analysis of BEAM vs Z-BEAM including 282 and 154 patients, respectively...
May 22, 2017: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/28530625/-robot-assisted-and-laparoscopic-pyeloplasty
#3
Juan Ignacio Pascual-Piédrola, Imanol Merino-Narro, Mateo Hevia-Suárez, Francisco Javier Ancizu-Marckert, Ángel García-Cortés, Pablo Domenech-López
OBJECTIVES: Uretero-pelvic junction (UPJ) obstruction has been classically treated by open dismembered pyeloplasty. Recently, laparoscopic (LP) and robotic pyeloplasty (RP) have become the techniques of choice for the treatment of UPJ stenosis in adult and pediatric population. Our objective in this paper is to review the results of minimally invasive surgery as the treatment of UPJ obstruction, the trend to use these approaches and the current limits of LP and RP. METHODS: A review of most relevant papers and meta-analysis about LP and RP in pediatric and adult population was performed using PubMed...
May 2017: Archivos Españoles de Urología
https://www.readbyqxmd.com/read/28530618/robotic-colposacropexy
#4
Miguel Angel Ruiz-León, Lorena Fernández-Montarroso, Natalia Pérez-Romero, Isabel Galante-Romo, Luis Eduardo Resel-Folkersma, Jesús Moreno-Sierra
OBJECTIVES: To review the role of robot- assisted laparoscopic colposacropexy (RALCS) as a treatment for pelvic organ prolapse (POP) accordingly with the available literature and our own experience. METHODS: We have analyzed the studies with the results of robot-assisted colposacropexy (RALCS) and others in which this technique is compared with the abdominal (ACS) and/or the laparoscopic approach (LCS), including our own series. The main data collected are surgical time, blood loss, complications, clinical outcomes, quality of life and the different costs of LCS versus RALCS...
May 2017: Archivos Españoles de Urología
https://www.readbyqxmd.com/read/28529537/a-web-based-tool-for-automatic-data-collection-curation-and-visualization-of-complex-healthcare-survey-studies-including-social-network-analysis
#5
José Alberto Benítez, José Emilio Labra, Enedina Quiroga, Vicente Martín, Isaías García, Pilar Marqués-Sánchez, Carmen Benavides
There is a great concern nowadays regarding alcohol consumption and drug abuse, especially in young people. Analyzing the social environment where these adolescents are immersed, as well as a series of measures determining the alcohol abuse risk or personal situation and perception using a number of questionnaires like AUDIT, FAS, KIDSCREEN, and others, it is possible to gain insight into the current situation of a given individual regarding his/her consumption behavior. But this analysis, in order to be achieved, requires the use of tools that can ease the process of questionnaire creation, data gathering, curation and representation, and later analysis and visualization to the user...
2017: Computational and Mathematical Methods in Medicine
https://www.readbyqxmd.com/read/28529383/the-pelskin-project-part-ii-investigating-the-physical-coupling-between-flexible-filaments-in-an-oscillating-flow
#6
Alistair Revell, Joseph O'Connor, Abhishek Sarkar, Cuicui Li, Julien Favier, Laura Kamps, Christoph Brücker
The fluid-structure interaction mechanisms of a coating composed of flexible flaps immersed in a periodically oscillating channel flow is here studied by means of numerical simulation, employing the Euler-Bernoulli equations to account for the flexibility of the structures. A set of passively actuated flaps have previously been demonstrated to deliver favourable aerodynamic impact when attached to a bluff body undergoing periodic vortex shedding. As such, the present configuration is identified to provide a useful test-bed to better understand this mechanism, thought to be linked to experimentally observed travelling waves...
2017: Meccanica
https://www.readbyqxmd.com/read/28528273/addition-of-thiols-to-the-double-bond-of-dipeptide-c-terminal-dehydroalanine-as-a-source-of-new-inhibitors-of-cathepsin-c
#7
Paweł Lenartowicz, Maciej Makowski, Bartosz Oszywa, Kinga Haremza, Rafał Latajka, Małgorzata Pawełczak, Paweł Kafarski
Addition of thiols to double bond of glycyl-dehydroalanine and phenyl-dehydroalanine esters provided micromolar inhibitors of cathepsin C. The structure-activity studies indicated that dipeptides containing N-terminal phenylalanine exhibit higher affinity towards the enzyme. A series of C-terminal S-substituted cysteines are responsible for varying interaction with S1 binding pocket of cathepsin C. Depending on diastereomer these compounds most likely act as slowly reacting substrates or competitive inhibitors...
May 17, 2017: Biochimie
https://www.readbyqxmd.com/read/28526652/retinoic-acid-induces-differentiation-of-buffalo-bubalus-bubalis-embryonic-stem-cells-into-germ-cells
#8
Syed Mohmad Shah, Suresh Kumar Singla, Prabhat Palta, Radhey Sham Manik, Manmohan Singh Chauhan
Development of precise and reproducible culture system for in vitro differentiation of embryonic stem (ES) cells into germ cells counts as a major leap forward for understanding not only the remarkable process of gametogenesis, otherwise obscured by limited availability of precursor primordial germ cells (PGCs), but in finally treating the catastrophic infertility. Taking into account the significant role of retinoic acid (RA) during in vivo gametogenesis, we designed the present study to investigate the effects of its stimulation on directing the differentiation of ES cells into germ cells...
May 16, 2017: Gene
https://www.readbyqxmd.com/read/28525991/correcting-for-day-of-the-week-and-public-holiday-effects-improving-a-national-daily-syndromic-surveillance-service-for-detecting-public-health-threats
#9
Elizabeth Buckingham-Jeffery, Roger Morbey, Thomas House, Alex J Elliot, Sally Harcourt, Gillian E Smith
BACKGROUND: As service provision and patient behaviour varies by day, healthcare data used for public health surveillance can exhibit large day of the week effects. These regular effects are further complicated by the impact of public holidays. Real-time syndromic surveillance requires the daily analysis of a range of healthcare data sources, including family doctor consultations (called general practitioners, or GPs, in the UK). Failure to adjust for such reporting biases during analysis of syndromic GP surveillance data could lead to misinterpretations including false alarms or delays in the detection of outbreaks...
May 19, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28525877/functional-network-connectivity-predicts-treatment-outcome-during-treatment-of-nicotine-use-disorder
#10
Claire E Wilcox, Vince D Calhoun, Srinivas Rachakonda, Eric D Claus, Rae A Littlewood, Jessica Mickey, Pamela B Arenella, Kent E Hutchison
Altered resting state functional connectivity (rsFC) and functional network connectivity (FNC), which is a measure of coherence between brain networks, may be associated with nicotine use disorder (NUD). We hypothesized that higher connectivity between insula and 1) dorsal anterior cingulate cortex (dACC) and 2) dorsolateral prefrontal cortex (dlPFC) would predict better treatment outcomes. We also performed an exploratory analysis of the associations between FNC values between additional key frontal and striatal regions and treatment outcomes...
April 30, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28525616/a-community-laboratory-drop-off-option-for-bowel-screening-test-kits-increases-participation-rates-results-from-an-interrupted-time-series-analysis
#11
P Sandiford, A Buckley, T Robinson, G Tozer, D Holdsworth, J Badkar
Background: Countries with population-based colorectal cancer screening using faecal occult blood test kits performed in the home and posted to the laboratory struggle to achieve higher than 60% uptake. We measured the impact on participation of offering a community laboratory drop-off (CLD) alternative to postal return in New Zealand's Bowel Screening Pilot. Methods: From May to September, 2015, a flyer added to the bowel screening test kit offered CLD as an alternative to returning the kit by post...
May 19, 2017: Journal of Public Health
https://www.readbyqxmd.com/read/28524113/is-increasing-coal-seam-gas-well-development-activity-associated-with-increasing-hospitalisation-rates-in-queensland-australia-an-exploratory-analysis-1995-2011
#12
Angela K Werner, Cate M Cameron, Kerrianne Watt, Sue Vink, Paul Jagals, Andrew Page
The majority of Australia's coal seam gas (CSG) reserves are in Queensland, where the industry has expanded rapidly in recent years. Despite concerns, health data have not been examined alongside CSG development. This study examined hospitalisation rates as a function of CSG development activity in Queensland, during the period 1995-2011. Admissions data were examined with CSG well numbers, which served as a proxy for CSG development activity. Time series models were used to assess changes in hospitalisation rates for periods of "low", "medium", "high", and "intense" activity compared to a period of "very low" activity, adjusting for covariates...
May 18, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28523608/excess-mortality-in-2015-a-time-series-and-cause-of-death-analysis-in-northern-italy
#13
Ugo Fedeli, Giulia Capodaglio, Elena Schievano, Eliana Ferroni, Maria Chiara Corti
AIMS: To investigate the excess mortality registered in the Veneto Region (Northern Italy) in 2015. METHODS: A Seasonal Autoregressive Integrated Moving Average Model was applied to predict overall mortality expected in 2014-2015 based on that observed in 2000-2013. The annual percent change in age-standardized rates (APC) was estimated for specific causes of death in 2007-2015. RESULTS: Compared to 2014, the number of deaths and the overall age-standardized mortality increased in 2015 by 7...
May 18, 2017: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/28523340/patient-and-surgical-characteristics-that-affect-revision-risk-in-dynamic-intraligamentary-stabilization-of-the-anterior-cruciate-ligament
#14
Philipp Henle, Kathrin S Bieri, Manuel Brand, Emin Aghayev, Jessica Bettfuehr, Janosch Haeberli, Martina Kess, Stefan Eggli
PURPOSE: Failure of dynamic intraligamentary stabilization (DIS) that requires revision surgery of the anterior cruciate ligament (ACL) has not been studied. The aim of this study was to investigate the incidence of revision ACL surgery, and the patient characteristics and surgery-related factors that are associated with an increased risk of ACL revision after DIS. METHODS: This study analysed a prospective, consecutively documented single-centre case series using standardized case report forms over a 2...
May 18, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28523169/risk-factors-for-continuous-renal-replacement-therapy-after-surgical-repair-of-type-a-aortic-dissection
#15
Hai-Bo Wu, Wei-Guo Ma, Hong-Lei Zhao, Jun Zheng, Jian-Rong Li, Ou Liu, Li-Zhong Sun
BACKGROUND: To identify the risk factors for continuous renal replacement therapy (CRRT) following surgical repair of type A aortic dissection (TAAD) using the total arch replacement and frozen elephant trunk (TAR + FET) technique. METHODS: The study included 330 patients with TAAD repaired using TAR + FET between January 2014 and April 2015. Mean age was 47.1±10.2 years (range, 18-73 years) and 242 were male (73.3%). Univariate and multivariate analyses were used to identify the risk factors for CRRT...
April 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28522232/efficacy-of-new-measures-saving-time-in-acute-stroke-management-a-quantified-analysis
#16
Ana María Iglesias Mohedano, Andrés García Pastor, Fernando Díaz Otero, Pilar Vázquez Alen, Marta Vales Montero, Elisa Luque Buzo, Nuria Redondo Ráfales, Beatriz Chavarria Cano, Yolanda Fernández Bullido, Jose Antonio Villanueva Osorio, Antonio Gil Núñez
BACKGROUND: Time to treatment remains the most important factor in acute ischemic stroke prognosis. We quantified the effect of new interventions reducing in-hospital delays in acute stroke management and assessed its repercussion on door-to-imaging (DTI), imaging-to-needle (ITN), and door-to-needle (DTN) times. METHODS: Prospective registry of consecutive stroke patients who were candidates for reperfusion therapy attended in a tertiary care hospital from February 1 to December 31, 2014...
May 15, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28521750/data-for-improvement-and-clinical-excellence-a-report-of-an-interrupted-time-series-trial-of-feedback-in-home-care
#17
Kimberly D Fraser, Anne E Sales, Melba Andrea B Baylon, Corinne Schalm, John J Miklavcic
BACKGROUND: There is substantial evidence about the effectiveness of audit with feedback, but none that we know have been conducted in home care settings. The primary purpose of the Data for Improvement and Clinical Excellence - Home Care (DICE-HC) project was to evaluate the effects of an audit and feedback delivered to care providers on home care client outcomes. The objective of this paper is to report the effects of feedback on four specific quality indicators: pain, falls, delirium, and hospital visits...
May 18, 2017: Implementation Science: IS
https://www.readbyqxmd.com/read/28521087/assessment-of-electron-propagator-methods-for-the-simulation-of-vibrationally-resolved-valence-and-core-photoionization-spectra
#18
Alberto Baiardi, Lorenzo Paoloni, Vincenzo Barone, Viatcheslav G Zakrzewski, Joseph Vincent Ortiz
The analysis of photoelectron spectra is usually facilitated by quantum mechanical simulations. Due to the recent improvement of experimental techniques, the resolution of experimental spectra is rapidly increasing, and the inclusion of vibrational effects is usually mandatory to obtain a reliable reproduction of the spectra. With the aim of defining a robust computational protocol, a general time-independent formulation to compute different kinds of vibrationally-resolved electronic spectra has been generalized to support also photoelectron spectroscopy...
May 18, 2017: Journal of Chemical Theory and Computation
https://www.readbyqxmd.com/read/28520761/antibiotic-use-in-south-korea-from-2007-to-2014-a-health-insurance-database-generated-time-series-analysis
#19
Juhee Park, Euna Han, Soo Ok Lee, Dong-Sook Kim
BACKGROUND: Inappropriate antibiotic use significantly contributes to antibiotic-resistance, resulting in reduced antibiotic efficacy and increasing physical burden and cost of disease. The goal of this study was to explore antibiotic usage patterns in South Korea using 2007-2014 health insurance claims data. METHODS: We used the Health Insurance Review & Assessment Service data, which represents nearly the entire population of South Korea, to discern patterns in antibiotic prescribing practices...
2017: PloS One
https://www.readbyqxmd.com/read/28520678/anterior-cruciate-ligament-injury-at-the-time-of-anterior-tibial-spine-fracture-in-young-patients-an-observational-cohort-study
#20
Meredith H Mayo, Justin J Mitchell, Derek P Axibal, Jorge Chahla, Claire Palmer, Armando F Vidal, Jason T Rhodes
BACKGROUND: Anterior tibial spine fractures (ATSF) in the skeletally immature parallel anterior cruciate ligament (ACL) tears in adult patients, yet these injuries are generally regarded as mutually exclusive. Biomechanical analysis suggests that intrinsic ACL damage occurs during ATSF, and long-term clinical studies demonstrate residual anteroposterior knee laxity following ATSF. We aim to describe prevalence, demographics, and characteristics of pediatric patients who sustained ATSF with concomitant ACL injury...
May 17, 2017: Journal of Pediatric Orthopedics
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