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Adrenal pseudotumor

Tao Wu, Pingyu Zhu, Xi Duan, Xuesong Yang, Dongliang Lu
Calcifying fibrous pseudotumor (CFP) is a rare benign soft tissue lesion. We herein present an extremely rare case of CFP of the adrenal gland. A 32-year-old male patient presented to our hospital with a tumor-like lesion in the area of the left adrenal gland detected by ultrasound during a routine check-up several days prior. Contrast-enhanced magnetic resonance imaging examination revealed a solitary, well-circumscribed mass, in close proximity to the medial arterial branch of the left adrenal gland. Histological examination revealed that the tumor consisted of sheets of varying amount of inflammatory cell infiltration; interstitial fibrosis and psammomatous calcifications were also observed...
September 2016: Molecular and Clinical Oncology
Geoffrey C Colin, David Vancraeynest, Delphine Hoton, Paul Jonard, Bernhard Gerber
No abstract text is available yet for this article.
October 27, 2015: Circulation
Jennifer C Alyono, Yangyang Shi, Gerald J Berry, Lawrence D Recht, Griffith R Harsh, Robert K Jackler, C Eduardo Corrales
OBJECTIVE: To describe the presentation, treatment, and outcome of inflammatory pseudotumors (IPs) of the skull base. DATA SOURCES: English-language articles in PubMed, Web of Science, and EMBASE from earliest available through April 2014. STUDY SELECTION: Articles were identified using a keyword search for "inflammatory pseudotumor," "inflammatory myofibroblastoma," or "plasma cell granuloma," including a keyword localizing to the skull base...
September 2015: Otology & Neurotology
Atsushi Okano, Hirofumi Nakatomi, Junji Shibahara, Tsukasa Tsuchiya, Nobuhito Saito
BACKGROUND: Immunoglobulin G (IgG)4-related disease is a syndrome that forms inflammatory pseudotumors with increasing IgG4-positive plasma cells and lymphocytes infiltrating the exocrine gland and other organs. The concept of this disease gradually has gained more recognition. However, reports of intracranial pseudotumors associated with IgG4-related disease are very rare. The purpose of this report is to provide further information helpful in distinguishing IgG4-related disease from multiple meningiomas...
June 2015: World Neurosurgery
Takashi Karashima, Yoshinori Taniguchi, Tsutomu Shimamoto, Tomoya Nao, Hiroshi Nishikawa, Satoshi Fukata, Masayuki Kamada, Keiji Inoue, Kentaro Oko, Hideki Nakajima, Shigetoshi Sano, Manabu Matsumoto, Naoto Kuroda, Yoshihiro Kamei, Taro Shuin
BACKGROUND: We report a case of a 33-year-old man who presented with immunoglobulin (Ig)G4-related disease (IgG4-RD) forming a pseudotumor in the left paratesticular region during oral administration of corticosteroid for Wells syndrome, which involves cellulitis with eosinophilia. CASE PRESENTATION: The patient was introduced to our institution from a private hospital with a 3-month history of asymptomatic left scrotal mass. A 5-cm diameter nodule was palpable in the left scrotum...
2014: Diagnostic Pathology
Claire A Sheldon, Young Joon Kwon, Grant T Liu, Shana E McCormack
Pseudotumor cerebri syndrome (PTCS) is defined by the presence of elevated intracranial pressure (ICP) in the setting of normal brain parenchyma and cerebrospinal fluid (CSF). Headache, vision changes, and papilledema are common presenting features. Up to 10% of appropriately treated patients may experience permanent visual loss. The mechanism(s) underlying PTCS is unknown. PTCS occurs in association with a variety of conditions, including kidney disease, obesity, and adrenal insufficiency, suggesting endocrine and/or metabolic derangements may occur...
February 2015: Pediatric Research
Stuti V Desai, Eleonora F Spinazzi, Christina H Fang, Grace Huang, Senja Tomovic, James K Liu, Soly Baredes, Jean Anderson Eloy
OBJECTIVES/HYPOTHESIS: Inflammatory pseudotumor is a benign idiopathic inflammatory process often misdiagnosed as an infection or neoplasm. This review analyzes all reported cases of sinonasal and ventral skull base inflammatory pseudotumor to date, and provides a framework for evaluation and management of this uncommon condition. DATA SOURCES: MEDLINE/PubMed database. REVIEW METHODS: A search for articles related to sinonasal and ventral skull base inflammatory pseudotumor, along with bibliographies of those articles, was performed...
April 2015: Laryngoscope
Matthew A Kutny, John Gregory, James H Feusner
Acute promyelocytic leukaemia (APL) in children and adolescents shares many features with APL in adults. There are important distinctions, however, between these age groups in the presentation, complications and treatment outcomes. Paediatric patients are more likely to present with high risk features including elevated WBC count or microgranular variant (M3v). Yet the early death rate is lower in paediatric patients compared to adult patients. Overall outcomes such as CR, OS and EFS appear similar in paediatric and adult patients treated on similar regimens except that very young children may have a higher risk of relapse...
March 2014: Best Practice & Research. Clinical Haematology
Aynur Ozge, Hayrunnisa Bolay
The specific aim of this review is to report the features of intracranial pressure changes [spontaneous intracranial hypotension (SIH) and idiopathic intracranial hypertension (IIH)] in children and adolescents, with emphasis on the presentation, diagnosis, and treatment modalities. Headache associated with intracranial pressure changes are relatively rare and less known in children and adolescents. SIH is a specific syndrome involving reduced intracranial pressure with orthostatic headache, frequently encountered connective tissue disorders, and a good prognosis with medical management, initial epidural blood patching, and sometimes further interventions may be required...
July 2014: Current Pain and Headache Reports
Smiti Sripathi, Poonam Mohan Shenoy, Anurag Ayachit, Rajagopal Kadavigere
Sclerosing pseudotumour of the orbit is a rare idiopathic chronic inflammatory process, which greatly mimics neoplasms both clinically and on imaging studies. It is therefore important to differentiate this entity from true neoplasms and to rule out any systemic associations. We present a rare case of sclerosing orbital pseudotumour in an adult man with no systemic illnesses who presented with painless progressive proptosis of both eyes and showed a gradual initial response to steroid therapy but relapsed after a 2-year interval...
2014: BMJ Case Reports
Ankur Girdhar, Amita Singh, Abubakr Bajwa, Adil Shujaat
Inflammatory pseudotumors are rare solid, non-neoplastic masses that can mimic pulmonary malignancy. It occurs most commonly in children and young adults and is usually found incidentally. There are many reports of the existence of this tumor in various organs in the human body. The occurrence of this tumor exclusively in the pleura has not been described before. We present a case of inflammatory pseudotumor of the pleura and its successful management.
April 2014: Journal of Bronchology & Interventional Pulmonology
Jianhua Yan, Peipei Wu
PURPOSE: There is a paucity of reliable data and limited experience on the clinical features and therapeutic outcomes of orbital myositis. The purpose of this study was to collate data on the clinical features, imaging, diagnosis, and therapeutic effects of case reports from patients with myositis of idiopathic orbital inflammation pseudotumor in a tertiary eye hospital in China. METHODS: A retrospective study was performed on the records of 44 Chinese patients with orbital myositis...
May 2014: Journal of Craniofacial Surgery
Sheldon Chong, Carren Teh, Singh Shashinder, Kein Seong Mun, Subrayan Viswaraja
Inflammatory pseudotumor (IPT) is a rare, locally aggressive, benign neoplasm of unknown etiology. It is uncommon in the head and neck region, particularly in the paranasal sinuses. We present an unusual case of IPT of the maxillary sinus and orbit in a 27-year-old woman who presented with cheek swelling, right orbital swelling, double vision, and associated fever and trismus. Computed tomography identified a mass with radiologic features suggestive of a malignancy of the maxillary sinus and orbit; the mass extended into the infratemporal fossa, parapharyngeal space, anterior antral wall, and surrounding soft tissue...
March 2014: Ear, Nose, & Throat Journal
Steven B Graff-Radford, Wouter I Schievink
BACKGROUND: Headache resulting from idiopathic intracranial hypertension (IIH) in a population of moderately to obese women of childbearing age. The causes overall remain unclear. With this review, we provide an overview of clinical treatment and management strategies. RESULTS: IIH management is dependent on the signs and symptoms presented. Symptomatic treatment should attempt to lower intracranial pressure, reduce pain, and protect the optic nerves. Consideration for lumbar puncture and draining fluid as an option for reducing pressure may be helpful; however, repeated treatment is not usually favored by patients...
February 2014: Headache
V Aldasoro-Cáceres, I Aldasoro-Cáceres, J V Pérez-Moreiras, M Murié-Fernández, R Ibáñez-Bosch
CASE REPORT: A patient diagnosed with necrotizing scleritis, c-ANCA+ an orbital pseudotumour, and possible multiple sclerosis in 2003 was treated with oral cyclophosphamide and steroids with partial response. Between 2005-2010 she suffered self-limited episodes. In 2010 a first scleral transplant was performed with poor outcome. She was treated with rituximab, and a second graft was performed with good results. At 12 months there was no change in magnetic resonance and the second graft healed...
January 2014: Archivos de la Sociedad Española de Oftalmología
H Stiebel-Kalish, S Eyal, I Steiner
Idiopathic intracranial hypertension is a common disorder affecting mainly healthy, young, overweight women. The pathogenesis of this condition is unknown, but it has been shown to follow treatment with several compounds including corticosteroids and vitamin A derivatives. This paper will offer a novel hypothesis and insight on the pathogenesis of drug induced intracranial hypertension following a review and analysis of the literature. Both corticosteroids and vitamin A derivatives have been shown to upregulate the expression of aquaporin 1, a water channel protein...
December 2013: Medical Hypotheses
María Celeste Buompadre
INTRODUCTION: Functional impairment of the optic nerve is characterized by visual loss, dyschromatopsia, visual field defects, relative afferent pupillary defect, and swelling or atrophy of the optic nerve. AIM: To describe the spectrum of acute optic neuropathies, focusing on clinical features, diagnosis and treatment with an emphasis on pediatric entities. DEVELOPMENT: Optic neuritis may be monophasic, recurrent, or part of a polysymptomatic demyelinating process...
September 6, 2013: Revista de Neurologia
Zhi-gang Chu, Fa-jin Lv, Zhi-yu Zhu, Yu Ouyang
BACKGROUND: Primary echinococcosis, and especially primary alveolar echinococcosis (AE) is rare among adrenal lesions. METHODS: We report a case of primary AE in a 28-year-old male with low backache and occasional upper limb pain lasting for six months, and review the pertinent but sparse literature on this disorder. RESULTS: Evaluation of the patient revealed an abdominal mass as right adrenal AE. The adrenal gland is a rare extrahepatic site of occurrence of echinococcosis, and particularly of AE...
August 2013: Surgical Infections
M Usman Khan, Heena Khalid, Vincenzo Salpietro, Karl T Weber
BACKGROUND: Idiopathic intracranial hypertension (IIH) is a syndrome consisting of headache, visual field defects and papilledema of uncertain etiology. The prospect was raised previously as to an association between aldosteronism and increased intracranial pressure in 2 middle-aged women with IIH and primary aldosteronism (PAL). Since then, 2 additional adults were identified and 2 other cases were reported from the United Kingdom, whereas 6 cases of IIH and secondary aldosteronism (SAL) in children have been reported in the English literature worldwide...
September 2013: American Journal of the Medical Sciences
Vincenzo Salpietro, Agata Polizzi, Luca Francesco Bertè, Roberto Chimenz, Valeria Chirico, Sara Manti, Valeria Ferraù, Annamaria Salpietro, Teresa Arrigo, Martino Ruggieri
The clinical syndrome idiopathic intracranial hypertension (IIH), also termed pseudotumor cerebri, consists of symptoms of headache, nausea, vomiting and visual field defects in combination with findings of papilledema. IIH is more commonly seen in overweight women where the rise in intracranial pressure is putatively a consequence of an endocrine-based disturbance of electrolytes. Less frequently, it can also occur in men and in the pediatric age group. Associated risk factors include primary and secondary aldosteronism, pregnancy, recombinant growth hormone (r-GH) therapy, oral contraceptives, obesity, vitamin A intoxication or deficiency, Addison disease, corticosteroid therapy or acute withdrawal of steroid therapy and Cushing disease...
2012: Neuro Endocrinology Letters
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