keyword
MENU ▼
Read by QxMD icon Read
search

Internal medicine

keyword
https://www.readbyqxmd.com/read/29909405/long-story-short-an-introduction-to-the-short-term-and-long-term-six-sigma-quality-and-its-importance-in-the-laboratory-medicine-for-the-management-of-extra-analytical-processes
#1
Cristiano Ialongo, Sergio Bernardini
There is a compelling need for quality tools that enable effective control of the extra-analytical phase. In this regard, Six Sigma seems to offer a valid methodological and conceptual opportunity, and in recent times, the International Federation of Clinical Chemistry and Laboratory Medicine has adopted it for indicating the performance requirements for non-analytical laboratory processes. However, the Six Sigma implies a distinction between short-term and long-term quality that is based on the dynamics of the processes...
June 18, 2018: Clinical Chemistry and Laboratory Medicine: CCLM
https://www.readbyqxmd.com/read/29909069/antimalarial-activity-of-single-dose-dsm265-a-novel-plasmodium-dihydroorotate-dehydrogenase-inhibitor-in-patients-with-uncomplicated-plasmodium-falciparum-or-plasmodium-vivax-malaria-infection-a-proof-of-concept-open-label-phase-2a-study
#2
Alejandro Llanos-Cuentas, Martin Casapia, Raúl Chuquiyauri, Juan-Carlos Hinojosa, Nicola Kerr, Maria Rosario, Stephen Toovey, Robert H Arch, Margaret A Phillips, Felix D Rozenberg, Jade Bath, Caroline L Ng, Annie N Cowell, Elizabeth A Winzeler, David A Fidock, Mark Baker, Jörg J Möhrle, Rob Hooft van Huijsduijnen, Nathalie Gobeau, Nada Araeipour, Nicole Andenmatten, Thomas Rückle, Stephan Duparc
BACKGROUND: DSM265 is a novel, long-duration inhibitor of plasmodium dihydroorotate dehydrogenase (DHODH) with excellent selectivity over human DHODH and activity against blood and liver stages of Plasmodium falciparum. This study aimed to assess the efficacy of DSM265 in patients with P falciparum or Plasmodium vivax malaria infection. METHODS: This proof-of-concept, open-label, phase 2a study was conducted at the Asociación Civil Selva Amazónica in Iquitos, Peru...
June 13, 2018: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/29908767/a-qualitative-cross-sectional-study-of-positive-and-negative-comments-of-residency-programs-across-9-medical-and-surgical-specialties
#3
Brittany O Dulmage, Lisa Akintilo, Leah J Welty, Matthew M Davis, Maria Colavincenzo, Shuai Xu
IMPORTANCE: Residency applicants often use social media to discuss the positive and negative features of prospective training programs. An examination of the content discussed by applicants could provide guidance for how medical education faculty can better engage with prospective trainees and adapt to meet the educational expectations of a new generation of digital-native physicians. OBJECTIVE: To identify unstructured social media data submitted by residency applicants and categorize positive and negative statements to determine key themes DESIGN: Qualitative analysis of a retrospective cohort SETTING: Publically available data sets PARTICIPANTS: Anonymized medical trainees applying to residency training positions in nine specialties: dermatology, general surgery, internal medicine, obstetrics/gynecology, plastic surgery, otolaryngology, physical medicine and rehabilitation, pediatrics, and radiology from 2007 to 2017...
June 14, 2018: American Journal of Medicine
https://www.readbyqxmd.com/read/29908468/first-report-on-the-pharmacokinetic-profile-of-nimbolide-a-novel-anticancer-agent-in-oral-and-intravenous-administrated-rats-by-lc-ms-method
#4
Shandilya Mahamuni Baira, Amit Khurana, Jaganmohan Somagoni, R Srinivas, Chandraiah Godugu, M V N Kumar Talluri
Nimbolide is a novel, natural compound with promising potential as a drug candidate for anticancer activity. It is isolated from the Indian traditional medicinal plant Azadirachta indica popularly known as neem. The present study was undertaken to explore the oral bioavailability and pharmacokinetic characteristics of nimbolide in rats using the LC/QTOF/MS method. A simple protein precipitation method using acetonitrile was employed for extracting nimbolide from rat plasma. The chromatographic separation of nimbolide and the internal standard (regorafenib) was attained on an Aquity BEH C18 column (100 × 2...
June 2, 2018: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/29907558/resident-and-attending-physicians-perceptions-of-patient-access-to-provider-notes-comparison-of-perceptions-prior-to-pilot-implementation
#5
Deepa Rani Nandiwada, Gary S Fischer, Glenn Updike, Margaret B Conroy
BACKGROUND: As electronic health records have become a more integral part of a physician's daily life, new electronic health record tools will continue to be rolled out to trainees. Patient access to provider notes is becoming a more widespread practice because this has been shown to increase patient empowerment. OBJECTIVE: In this analysis, we compared differences between resident and attending physicians' perceptions prior to implementation of patient access to provider notes to facilitate optimal use of electronic health record features and as a potential for patient empowerment...
June 15, 2018: JMIR Medical Education
https://www.readbyqxmd.com/read/29906268/combined-international-external-quality-assessment-results-of-medical-laboratory-performance-and-reporting-of-samples-with-known-antimicrobial-resistance
#6
Michael A Noble, Robert Rennie
BACKGROUND: Reporting on the presence of antimicrobial resistance is of considerable concern both for individual patient care and for understanding the underlying health status within the community at large. Antimicrobial resistance is solely dependent upon clinical laboratory detection and thus can be impacted upon by the quality and competence of medical laboratories. Proficiency testing or external quality assessment (PT/EQA) is the international standard for the direct measurement of medical laboratory performance on critical testing...
June 15, 2018: Diagnosis
https://www.readbyqxmd.com/read/29905758/short-stay-unit-hospitalisation-vs-standard-care-outcomes-in-older-internal-medicine-patients-a-randomised-clinical-trial
#7
Camilla Strøm, Lars Simon Rasmussen, Anne-Sophie Löwe, Anne Kathrine Lorentzen, Nicolai Lohse, Kim Hvid Benn Madsen, Søren Wistisen Rasmussen, Thomas Andersen Schmidt
Background: the effect of hospitalisation in emergency department-based short-stay units (SSUs) has not been studied in older patients. We compared SSU hospitalisation with standard care at an Internal Medicine Department (IMD) in acutely admitted older internal medicine patients. Methods: pragmatic randomised clinical trial. We randomly assigned patients aged 75 years or older, acutely admitted for an internal medicine disease and assessed to be suitable for SSU hospitalisation to SSU hospitalisation or IMD hospitalisation...
June 13, 2018: Age and Ageing
https://www.readbyqxmd.com/read/29905489/assisted-reproductive-technology-comorbidities-and-cardiovascular-risk-the-experience-of-an-italian-center
#8
Cinzia Fatini, Michela Cirillo, Maria Elisabetta Coccia
BACKGROUND: A growing number of infertile women undergo assisted reproductive technology (ART). Older maternal age and the presence of comorbidities may affect cardiovascular (CV) women health. Safety aspects are central in risk assessment; we report the experience of internal medicine clinical setting at the ART center. MATERIALS AND METHODS: we investigated 243 infertile women (110 autologous and 133 oocyte donation [OD]); cardiometabolic parameters and CV risk factors were investigated during the clinical evaluation...
June 15, 2018: Journal of Women's Health
https://www.readbyqxmd.com/read/29905108/publication-rate-of-avian-medicine-conference-abstracts-and-influencing-factors-2011-2015
#9
Christina Doukaki, Dr MedVet, Hugues Beaufrère, Dr Med Vet, Minh Huynh
International conferences on avian medicine and surgery aim to disseminate scientific and evidence-based information in the form of oral presentations and posters. Most manuscripts presented are printed in the conference proceedings as abstracts. Subsequent publication in a scientific peer-reviewed journal is the natural outcome of the research cycle, although studies have shown that the vast majority of conference abstracts are not published. The purpose of this study was to explore 1) the fate of abstracts presented in avian conferences (Association of Avian Veterinarians, European Association of Avian Veterinarians, International Conference on Avian Herpetological and Exotic Mammal Medicine) in the years 2011-2015, 2) assess the publication rate in peer-reviewed journals, 3) describe the time course of subsequent publication, and 4) identify factors associated with increased likelihood of publication...
June 2018: Journal of Avian Medicine and Surgery
https://www.readbyqxmd.com/read/29904585/recent-advances-in-deep-brain-stimulation-in-psychiatric-disorders
#10
REVIEW
Anne-Hélène Clair, William Haynes, Luc Mallet
Deep brain stimulation (DBS) has been offered to patients suffering of severe and resistant neuropsychiatric disorders like Obsessive Compulsive Disorder (OCD), Gilles de la Tourette Syndrome (TS) and Major Depression (MDD). Modulation of several targets within the cortico-striato-thalamo-cortical circuits can lead to a decrease of symptom severity in those patients. This review focuses on the recent clinical outcomes in DBS in psychiatric disorders. Studies on OCD and TS are now focusing on the long-term effects of DBS, with encouraging results regarding not only the decrease of symptoms, but also quality of life...
2018: F1000Research
https://www.readbyqxmd.com/read/29904575/recent-advances-in-transfusions-in-neonates-infants
#11
REVIEW
Ruchika Goel, Cassandra D Josephson
Transfusions of red blood cells (RBCs), platelets, and plasma are critical therapies for infants and neonates (particularly preterm neonates) in the neonatal intensive care unit, who are the most frequently transfused subpopulation across all ages. Although traditionally a significant gap has existed between the blood utilization and the evidence base essential to adequately guide transfusion practices in infants and neonates, pediatric transfusion medicine is evolving from infancy and gradually coming of age...
2018: F1000Research
https://www.readbyqxmd.com/read/29904220/monographs-for-medicines-on-who-s-model-list-of-essential-medicines
#12
Lukas Roth, Melissa Adler, Tanvi Jain, Daniel Bempong
Objective: To raise awareness about the importance of public pharmaceutical standards, identify if and, if so, where current pharmacopeias are falling short in the development of new and complete monographs and foster collaboration among the various pharmacopeias, to prioritize, develop and make available standards for those key medicines for which no complete monographs exist. Methods: In August 2017, we mined eight pharmacopeias to identify which of the 669 medicines in the 20th edition of the World Health Organization's Model List of Essential Medicines were covered by complete or incomplete monographs...
June 1, 2018: Bulletin of the World Health Organization
https://www.readbyqxmd.com/read/29903642/awareness-use-and-applicability-of-online-risk-calculators-for-non-communicable-diseases-a-cross-sectional-study
#13
Andrea Schueck, Michael von Wolff, Norman Bitterlich, Petra Stute
Chronic non-communicable diseases (NCDs) are the major reason for death and morbidity worldwide. As many NCDs are initially asymptomatic, online risk calculators with easy and inexpensive access have been developed and validated in order to facilitate early NCD detection and prevention. The aim of this study was to assess the awareness, use and applicability of NCD risk calculators among physicians in private practice in the canton of Bern, Switzerland. This was a cross-sectional cohort study of general practitioners and specialists in general internal medicine and gynaecologists...
July 2018: Maturitas
https://www.readbyqxmd.com/read/29902910/-construction-of-high-quality-chrysanthemi-flos-pieces-standard-system-based-on-comprehensive-analysis-of-ancient-and-modern-chinese-and-foreign-pharmacopoeia
#14
Ying Dai, Hua-Qiang Zhai, Lian-Yu Xiao, Xiao-Song Shan, Zhi-Han Liu, Ning-Ning Wang, Si-Yu Li, Guo-Xiu Liu
To study the evolution of Chinese ancient and modern pharmacopoeia standards and compare the domestic and foreign pharmacopoeias, further understand the international requirements on chrysanthemum quality, and establish a more suitable and modern standard system for high quality Chrysanthemi Flos pieces. Newly Revised Materia Medica, Welfare Pharmacy, Collected Essentials of Species of Materia Medica (Bencao Pinhui Jingyao), Chinese Pharmacopoeia and other herbal remedies in various generations were reviewed to summarize the evolution of domestic standards on Chrysanthemi Flos pieces...
May 2018: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29901657/the-changing-face-of-hiv-care-expanding-hiv-training-in-internal-medicine-residency-program
#15
Lydia Aoun Barakat, Dana W Dunne, Jeanette M Tetrault, Sarita Soares, David Chia, Onyema E Ogbuagu, John P Moriarty, Stephen J Huot, Michael L Green
PROBLEM: HIV-infected patients are living longer and are at increased risk of comorbidities. A qualified physician workforce is needed to care for this growing HIV population. APPROACH: This report describes the first 5 years of the development and implementation of a novel 3-year HIV Training Track (HIV TT) within the Primary Care Residency Program from 2012 to 2017. It outlines the process of building the infrastructure of the HIV TT, describes the curriculum development based on HIV-specific Entrustable Professional Activities (EPA), and provides the results of the program evaluation in the 5 year period OUTCOMES:: The program enrolled a cohort of 11 trainees with 5 graduates...
June 12, 2018: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/29901637/extracranial-intracranial-bypass-in-medial-sphenoid-ridge-meningioma-associated-with-severe-stenosis-of-the-intracranial-segments-of-the-internal-carotid-artery-a-case-report
#16
Yabo Huang, Zhong Wang, Qingdong Han
RATIONALE: Tumor resection and extracranial-intracranial bypass concerning medial sphenoid ridge meningioma associated with severe stenosis of the internal carotid artery (ICA) of intracranial segments has been rarely presented. Effective treatment as to the complex lesions may be complicated. Tumor resection and cerebrovascular protection should be both taken into consideration. PATIENT CONCERNS: We presented one case of medial sphenoid ridge meningioma associated with severe stenosis of the internal carotid artery of intracranial segments...
June 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29901620/acupuncture-for-perimenopausal-insomnia-a-systematic-review-and-meta-analysis-protocol
#17
Taipin Guo, Man Jia, Yuhao Jin, Na Xu, Tianzhong Peng
BACKGROUND: Perimenopausal insomnia (PI) is one of the most common complaints in women. Acupuncture is used to treat PI increasingly considering its less side effect. The subject of this study is to explore the effectiveness and safety of acupuncture for PI. METHODS: All the randomized controlled trials(RCT) literatures of acupuncture for PI will be searched in the databases of MEDLINE, Cochrane Library, Web of Science, EMBASE, Springer, WHO International Clinical Trials Registry Platform (ICTRP), China National Knowledge Infrastructure (CNKI), Wan fang, Chinese Biomedical Literature Database (CBM), Chinese Scientific Journal Database (VIP), and other available resources using the subject terms of 'acupuncture" and "perimenopausal insomnia" and their synonyms...
June 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29901556/universal-recommendations-for-the-management-of-acute-diarrhea-in-non-malnourished-children
#18
Alfredo Guarino, Andrea Lo Vecchio, Jorge Amil Dias, James A Berkley, Chris Boey, Dario Bruzzese, Mitchell B Cohen, Sylvia Cruchet, Ilaria Liguoro, Eduardo Salazar-Lindo, Bhupinder Sandhu, Philip M Sherman, Toshiaki Shimizu
OBJECTIVES: Despite a substantial consistency in recommendations for the management of children with acute gastroenteritis (AGE), a high variability in clinical practice and a high rate of inappropriate medical interventions persist in both developing and developed countries.Aim of this study was to develop a set of clinical recommendations for the management of non-severely malnourished children with AGE to be applied worldwide. METHODS: The Federation of International Societies of Pediatric Gastroenterology, Hepatology, and Nutrition (FISPGHAN) Working Group (WG) selected care protocols on the management of acute diarrhea in infants and children aged between 1 month and 18 years...
June 12, 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29900976/turkish-league-against-rheumatism-consensus-report-recommendations-for-management-of-axial-spondyloarthritis
#19
Hatice Bodur, Fatma Gül Yurdakul, Şebnem Ataman, Yeşim Garip, Kemal Nas, Fikriye Figen Ayhan Fikriye Figen Ayhan, Özgür Akgül, Ayşen Akinci, Zuhal Altay, Murat Birtane, Derya Soy Buğdayci, Erhan Çapkin, Remzi Çevik, Tuncay Duruöz, Gülcan Gürer, Cahit Kaçar, Ayhan Kamanli, Ece Kaptanoğlu, Taciser Kaya, Hilal Kocabaş, Ömer Kuru, Meltem Alkan Melikoğlu, Erhan Özdemirel, Sumru Özel, Aylin Rezvani, İlhan Sezer, İsmihan Sunar, Gürkan Yilmaz
Objectives: This study aims to update 2011 Turkish League Against Rheumatism SpondyloArthritis Recommendations, and to compose a national expert opinion on management of axial spondyloArthritis under guidance of current guidelines, and implantation and dissemination of these international guidelines into our clinical practice. Patients and methods: A scientific committee of 28 experts consisting of 14 rheumatologists and 14 physical medicine and rehabilitation specialists (one of them also has an immunology PhD) was formed...
March 2018: Archives of Rheumatology
https://www.readbyqxmd.com/read/29898590/use-of-the-international-classification-of-functioning-disability-and-health-generic-30-set-for-the-characterization-of-outpatients-italian-society-of-physical-and-rehabilitative-medicine-residents-section-project
#20
Francesca Gimigliano, Alessandro De Sire, Marco Gastaldo, Irene Maghini, Marco Paoletta, Andrea Pasquini, Paolo Boldrini, Melissa Selb, Birgit Prodinger
BACKGROUND: The International Classification of Functioning, Disability and Health (ICF) Generic- 30 Set (previously referred to as Rehabilitation Set) is a minimal set of ICF categories for reporting and assessing functioning and disability in clinical populations with different health conditions along the continuum of care. Recently, the Italian Society of Physical and Rehabilitation Medicine (SIMFER) developed an Italian modification of the simple and intuitive descriptions (SID) of these categories...
June 11, 2018: European Journal of Physical and Rehabilitation Medicine
keyword
keyword
1210
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"