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https://www.readbyqxmd.com/read/29036950/-to-attach-great-importance-to-the-diagnosis-and-treatment-of-psychosomatic-disorders-in-internal-medicine
#1
W Z Wang
No abstract text is available yet for this article.
October 1, 2017: Zhonghua Nei Ke za Zhi [Chinese Journal of Internal Medicine]
https://www.readbyqxmd.com/read/29036749/-paediatrics-in-light-of-the-convention-on-the-rights-of-the-child
#2
Christoph Klein
The United Nations Convention on the Rights of the Child not only grants comprehensive rights to children via international law, it also constitutes a legally binding framework under German federal law. With respect to health care, the convention establishes the "right of the child to the enjoyment of the highest attainable standard of health" and the principle that "the best interests of the child shall be a primary consideration" in all actions undertaken by public or private institutions. Here, some fundamental aspects of the convention and the monitoring of its implementation are summarized and current challenges in paediatric medicine in Germany are discussed in light of the convention...
October 16, 2017: Das Gesundheitswesen
https://www.readbyqxmd.com/read/29036369/referral-of-patients-with-fever-of-unknown-origin-to-an-expertise-center-has-high-diagnostic-and-therapeutic-value
#3
Catharina M Mulders-Manders, Gianni Pietersz, Anna Simon, Chantal P Bleeker-Rovers
Background: up to 50% of patients with fever of unknown origin (FUO) remain undiagnosed despite extensive evaluation. In expertise centers, at least 25-63% of these patients is referred after evaluation in another hospital. The diagnostic and therapeutic yields of referral to an expertise center are currently unknown. Aim: To determine the diagnostic and therapeutic yield of referral of patients with fever of unknown origin (FUO) that remain undiagnosed in non-expertise hospitals...
July 28, 2017: QJM: Monthly Journal of the Association of Physicians
https://www.readbyqxmd.com/read/29036230/predictors-of-adverse-drug-reaction-related-hospitalisation-in-southwest-ethiopia-a-prospective-cross-sectional-study
#4
Mulugeta Tarekegn Angamo, Colin Michael Curtain, Leanne Chalmers, Daniel Yilma, Luke Bereznicki
BACKGROUND: Adverse drug reactions (ADRs) are important causes of morbidity and mortality in the healthcare system; however, there are no studies reporting on the magnitude and risk factors associated with ADR-related hospitalisation in Ethiopia. OBJECTIVES: To characterise the reaction types and the drugs implicated in admission to Jimma University Specialized Hospital, Southwest Ethiopia, and to identify risk factors associated with ADR-related hospitalisation...
2017: PloS One
https://www.readbyqxmd.com/read/29035190/brain-tumor-epidemiology-in-the-era-of-precision-medicine-the-2017-brain-tumor-epidemiology-consortium-meeting-report
#5
Kimberly J Johnson, Judith Schwartzbaum, Carol Kruchko, Michael E Scheurer, Ching C Lau, Adelheid Woehrer, Johannes A Hainfellner, Joseph Wiemels
The Brain Tumor Epidemiology Consortium (BTEC) is an international consortium that aims to advance the development of multicenter and interdisciplinary collaborations that focus on research related to the etiology, outcomes, and prevention of brain tumors. The 18th annual BTEC meeting was held in Banff, AB, Canada, on June 27 - 29, 2017. The meeting focused on the intersection between epidemiology and precision medicine, that is, the use of molecular indicators of risk, early disease and prognosis or precision epidemiology...
October 16, 2017: Clinical Neuropathology
https://www.readbyqxmd.com/read/29035006/applying-systems-thinking-to-inform-studies-of-wildlife-trade-in-primates
#6
Mary E Blair, Minh D Le, Hoàng M Thạch, Anna Panariello, Ngọc B Vũ, Mark G Birchette, Gautam Sethi, Eleanor J Sterling
Wildlife trade presents a major threat to primate populations, which are in demand from local to international scales for a variety of uses from food and traditional medicine to the exotic pet trade. We argue that an interdisciplinary framework to facilitate integration of socioeconomic, anthropological, and biological data across multiple spatial and temporal scales is essential to guide the study of wildlife trade dynamics and its impacts on primate populations. Here, we present a new way to design research on wildlife trade in primates using a systems thinking framework...
October 16, 2017: American Journal of Primatology
https://www.readbyqxmd.com/read/29034866/the-health-effects-of-aluminum-exposure
#7
Katrin Klotz, Wobbeke Weistenhöfer, Frauke Neff, Andrea Hartwig, Christoph van Thriel, Hans Drexler
BACKGROUND: Aluminum is regularly taken up with the daily diet. It is also used in antiperspirants, as an adjuvant for vaccination, and in desensitization procedures. In this review, we present the scientifically documented harmful effects of aluminum on health and the threshold values associated with them. METHODS: This review is based on publications retrieved by a selective search of the PubMed and SCOPUS databases on the topic of aluminum in connection with neurotoxicity, Alzheimer's disease, and breast cancer, as well as on the authors' personal experience in occupational and environmental medicine...
September 29, 2017: Deutsches Ärzteblatt International
https://www.readbyqxmd.com/read/29034514/measurement-of-murine-single-kidney-glomerular-filtration-rate-using-dynamic-contrast-enhanced-mri
#8
Kai Jiang, Hui Tang, Prasanna K Mishra, Slobodan I Macura, Lilach O Lerman
PURPOSE: To develop and validate a method for measuring murine single-kidney glomerular filtration rate (GFR) using dynamic contrast-enhanced MRI (DCE-MRI). METHODS: This prospective study was approved by the Institutional Animal Care and Use Committee. A fast longitudinal relaxation time (T1 ) measurement method was implemented to capture gadolinium dynamics (1 s/scan), and a modified two-compartment model was developed to quantify GFR as well as renal perfusion using 16...
October 16, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29034511/computationally-efficient-combination-of-multi-channel-phase-data-from-multi-echo-acquisitions-aspire
#9
Korbinian Eckstein, Barbara Dymerska, Beata Bachrata, Wolfgang Bogner, Karin Poljanc, Siegfried Trattnig, Simon Daniel Robinson
PURPOSE: To develop a simple method for combining multi-echo phase information from a number of coils in an array that requires no volume coil or additional scans and yields signal-to-noise ratio-optimal images that reflect only ΔB0-related phase. THEORY AND METHODS: Two SNR optimal coil combination methods were developed which retrieve the ΔB0-related phase by determining the coil-dependent phase offsets. The first variant, MCPC-3D-S, requires the unwrapping of one phase image; the second variant, ASPIRE, allows unwrapping to be avoided if two echoes j and k satisfy the echo time relation m⋅TEk=(m+1)⋅TEj, where m is an integer, making this a particularly fast and robust approach...
October 16, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29034509/3d-diffusion-weighted-129-xe-mri-for-whole-lung-morphometry
#10
Ho-Fung Chan, Neil J Stewart, Graham Norquay, Guilhem J Collier, Jim M Wild
PURPOSE: To obtain whole lung morphometry measurements from (129) Xe in a single breath-hold with 3D multiple b-value (129) Xe diffusion-weighted MRI (DW-MRI) with an empirically optimized diffusion time and compressed sensing for scan acceleration. METHODS: Prospective three-fold undersampled 3D multiple b-value hyperpolarized (129) Xe DW-MRI datasets were acquired, and the diffusion time (Δ) was iterated so as to provide diffusive length scale (LmD ) estimates from the stretched exponential model (SEM) that are comparable to those from (3) He...
October 16, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29034505/in-vivo-characterization-of-the-downfield-part-of-1-h-mr-spectra-of-human-brain-at-9-4-t-magnetization-exchange-with-water-and-relation-to-conventionally-determined-metabolite-content
#11
Nicole D Fichtner, Ioannis-Angelos Giapitzakis, Nikolai Avdievich, Ralf Mekle, Daniel Zaldivar, Anke Henning, Roland Kreis
PURPOSE: To perform exchange-rate measurements on the in vivo human brain downfield spectrum (5-10 ppm) at 9.4 T and to compare the variation in concentrations of the downfield resonances and of known upfield metabolites to determine potential peak labels. METHODS: Non-water-suppressed metabolite cycling was used in combination with an inversion transfer technique in two brain locations in healthy volunteers to measure the exchange rates and T1 values of exchanging peaks...
October 16, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29034502/ghost-reduction-in-echo-planar-imaging-by-joint-reconstruction-of-images-and-line-to-line-delays-and-phase-errors
#12
Julianna D Ianni, E Brian Welch, William A Grissom
PURPOSE: To correct line-to-line delays and phase errors in echo-planar imaging (EPI). THEORY AND METHODS: EPI-trajectory auto-corrected image reconstruction (EPI-TrACR) is an iterative maximum-likelihood technique that exploits data redundancy provided by multiple receive coils between nearby lines of k-space to determine and correct line-to-line trajectory delays and phase errors that cause ghosting artifacts. EPI-TrACR was efficiently implemented using a segmented FFT and was applied to in vivo brain data acquired at 7 T across acceleration (1×-4×) and multishot factors (1-4 shots), and in a time series...
October 16, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29034335/reliability-and-validity-of-the-lichtenberg-financial-decision-screening-scale
#13
Peter A Lichtenberg, Jeanne A Teresi, Katja Ocepek-Welikson, Joseph P Eimicke
The scarcity of empirically validated assessment instruments continues to impede the work of professionals in a number of fields, including medicine, finance, and estate planning; adult protective services; and criminal justice-and, more importantly, it impedes their ability to effectively assist and, in some case, protect their clients. Other professionals (e.g. legal, financial, medical, mental health services) are in a position to prevent financial exploitation and would benefit from access to new instruments...
March 1, 2017: Innov Aging
https://www.readbyqxmd.com/read/29033060/a-review-of-international-coverage-and-pricing-strategies-for-personalized-medicine-and-orphan-drugs
#14
REVIEW
Irina Degtiar
BACKGROUND: Personalized medicine and orphan drugs share many characteristics-both target small patient populations, have uncertainties regarding efficacy and safety at payer submission, and frequently have high prices. Given personalized medicine's rising importance, this review summarizes international coverage and pricing strategies for personalized medicine and orphan drugs as well as their impact on therapy development incentives, payer budgets, and therapy access and utilization...
September 29, 2017: Health Policy
https://www.readbyqxmd.com/read/29032820/methodological-quality-assessment-of-meta-analyses-in-endodontics
#15
REVIEW
Sereen Kattan, Su-Min Lee, Meetu R Kohli, Frank C Setzer, Bekir Karabucak
INTRODUCTION: The objectives of this review were to assess the methodological quality of published meta-analyses related to endodontics using the assessment of multiple systematic reviews (AMSTAR) tool and to provide a follow-up to previously published reviews. METHODS: Three electronic databases were searched for eligible studies according to the inclusion and exclusion criteria: Embase via Ovid, The Cochrane Library, and Scopus. The electronic search was amended by a hand search of 6 dental journals (International Endodontic Journal; Journal of Endodontics; Australian Endodontic Journal; Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology; Endodontics and Dental Traumatology; and Journal of Dental Research)...
October 9, 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/29031937/payer-database-and-geospatial-analysis-to-evaluate-practice-patterns-in-treating-allergy-in-north-carolina
#16
Matthew G Crowson, Kristine Schulz, Alex Ulvila, David L Witsell
OBJECTIVE: The objective of this study was to characterize the delivery of allergy care in North Carolina using a large payer charge database and visualization techniques. STUDY DESIGN: Geospatial database analysis. SETTING: North Carolina State claims database. SUBJECTS & METHODS: Medical data from the 2013 FAIR Health National Private Insurance Claims (FH NPIC) database for North Carolina was mined for CPT codes and charges for allergy testing, and for the preparation and provision of allergen immunotherapy...
October 10, 2017: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/29031873/does-specialty-matter-a-survey-on-176-italian-neurosurgeons-and-orthopaedic-spine-surgeons-confirms-similar-competency-for-common-spinal-conditions-and-supports-multidisciplinary-teams-in-comprehensive-and-complex-spinal-care
#17
Matteo Pejrona, Gabriele Ristori, Jorge Hugo Villafañe, Fabrizio Ernesto Pregliasco, Pedro Berjano
BACKGROUND CONTEXT: Spine surgery is a multi-faceted sub-speciality requiring a breadth of knowledge and skill from different branches of medicine for the treatment of pathologies varying from degenerative to deformity, oncological, and trauma. PURPOSE: The aim of the study was to investigate the self-perceived competency of spine surgeons in relation to different types of spinal procedures. STUDY DESIGN/SETTING: Survey study. METHODS: We conducted a survey on 176 surgeons (Orthopaedic surgeons and Neurosurgeons)...
October 11, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29030882/accelerated-multicontrast-volumetric-imaging-with-isotropic-resolution-for-improved-peri-infarct-characterization-using-parallel-imaging-low-rank-and-spatially-varying-edge-preserving-sparse-modeling
#18
Li Zhang, Peng Lai, Mihaela Pop, Graham A Wright
PURPOSE: To achieve consistent effectiveness in reconstruction of fine image features for cases of varying contrast-to-noise ratio (CNR) to facilitate translating accelerated multicontrast volumetric imaging with isotropic resolution toward clinical utility in peri-infarct characterization. THEORY AND METHODS: A low-rank and spatially varying edge-preserving constrained compressed sensing parallel imaging reconstruction method (CP-LASER) is developed to effectively preserve contrast of small-scale structures for highly accelerated multicontrast volumetric imaging in CNR-limited scenarios...
October 13, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29030880/direct-saturation-corrected-chemical-exchange-saturation-transfer-mri-of-glioma-simplified-decoupling-of-amide-proton-transfer-and-nuclear-overhauser-effect-contrasts
#19
Iris Yuwen Zhou, Enfeng Wang, Jerry S Cheung, Dongshuang Lu, Yang Ji, Xiaoan Zhang, Giulia Fulci, Phillip Zhe Sun
PURPOSE: Chemical exchange saturation transfer (CEST) MRI has shown promise in tissue characterization in diseases like stroke and tumor. However, in vivo CEST imaging such as amide proton transfer (APT) MRI is challenging because of concomitant factors such as direct water saturation, macromolecular magnetization transfer, and nuclear overhauser effect (NOE), which lead to a complex contrast in the commonly used asymmetry analysis (MTRasym). Here, we propose a direct saturation-corrected CEST (DISC-CEST) analysis for simplified decoupling and quantification of in vivo CEST effects...
October 13, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29030876/reproducibility-of-cmro2-determination-using-dynamic-17-o-mri
#20
Sebastian C Niesporek, Reiner Umathum, Jonathan M Lommen, Nicolas G R Behl, Daniel Paech, Peter Bachert, Mark E Ladd, Armin M Nagel
PURPOSE: To assess the reproducibility of (17) O MRI-based determination of the cerebral metabolic rate of oxygen consumption (CMRO2 ) in healthy volunteers. To assess the influence of image acquisition and reconstruction parameters on dynamic quantification of functional parameters such as CMRO2 . METHODS: Dynamic (17) O MRI data were simulated and used to investigate influences of temporal resolution (Δt) and partial volume correction (PVC) on the determination of CMRO2 ...
October 13, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
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