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https://www.readbyqxmd.com/read/28231623/compassion-fatigue-in-nurses-a-metasynthesis
#1
Anna G W Nolte, Charlene Downing, Annie Temane, Marie Hastings-Tolsma
AIM: The purpose of this research was to interpret the body of qualitative work focusing on compassion fatigue to distill a common understanding that could then be applied to nursing care. BACKGROUND: Complex demands place extraordinary stress on nurses struggling to work in overburdened healthcare systems. The result can be the inability to care well for others, leading to compassion fatigue, burnout, and increased numbers leaving the profession. Meta-synthesis offers a means of more fully illuminating compassion fatigue and further understanding of practices which might reduce its negative consequences...
February 23, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28231604/variations-in-body-morphology-explain-gender-differences-in-thermoeffector-function-during-compensable-heat-stress
#2
Sean R Notley, Joonhee Park, Kyoko Tagami, Norikazu Ohnishi, Nigel A S Taylor
Gender is sometimes thought to independently modulate cutaneous vasomotor and sudomotor function during heat exposure. Nevertheless, it was hypothesised that, when assessed during compensable exercise that evoked equal heat-loss requirements across participants, gender differences in those thermoeffectors would be explained by variations in the ratio between body surface area and mass (specific surface area). To evaluate that possibility, vasomotor and sudomotor functions were assessed in sixty individuals (36 males, 24 females) with widely varying (overlapping) specific surface areas (range: 232...
February 23, 2017: Experimental Physiology
https://www.readbyqxmd.com/read/28229110/reliability-of-the-chronic-mild-stress-model-of-depression-a-user-survey
#3
Paul Willner
The chronic mild stress (CMS) model of depression is considered by many to be the animal model of depression that has the greatest validity and translational potential, but it has often been criticized for a perceived lack of reliability. The aims of this study were to establish the extent to which the procedure is reproducible, and to identify experimental variables relevant to its reliability. Because failures to replicate frequently remain unpublished, a survey methodology was used. A questionnaire was circulated to 170 labs identified from a PubMed search as having published a CMS study in the years 2010 or 2015 (with no selection in respect of the results reported)...
February 2017: Neurobiology of Stress
https://www.readbyqxmd.com/read/28227067/computational-estimation-of-the-severity-of-coronary-lesions-with-intravascular-ultrasound-images-a-pilot-study
#4
Panagiotis K Siogkas, Michail I Papafaklis, Bill D Gogas, Habib Samady, Lampros K Michalis, Dimitrios I Fotiadis, Panagiotis K Siogkas, Michail I Papafaklis, Bill D Gogas, Habib Samady, Lampros K Michalis, Dimitrios I Fotiadis, Bill D Gogas, Habib Samady, Michail I Papafaklis, Dimitrios I Fotiadis, Panagiotis K Siogkas, Lampros K Michalis
The fast and accurate hemodynamic functional assessment of the coronary vasculature is of utmost importance in clinical practice due to the fact that Cardiovascular Diseases have become the leading cause of death globally. In this work we propose a novel method that combines two of the most efficient methods of hemodynamic status assessment of coronary arteries, Intravascular UtraSound and virtual Functional Assessment Index, an index that correlates well to the measured Fractional Flow Reserve. One Left Anterior Descending segment was reconstructed both in a straight manner (using only IVUS images) as well as using the actual 3D geometry of the vessel (using IvUS images combined with the respective coronary angiographic images [2])...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28224921/lemna-minor-plants-chronically-exposed-to-ionising-radiation-rna-seq-analysis-indicates-a-dose-rate-dependent-shift-from-acclimation-to-survival-strategies
#5
Arne Van Hoeck, Nele Horemans, Robin Nauts, May Van Hees, Hildegarde Vandenhove, Ronny Blust
Ecotoxicological research provides knowledge on ionising radiation-induced responses in different plant species. However, the sparse data currently available are mainly extracted from acute exposure treatments. To provide a better understanding of environmental exposure scenarios, the response to stress in plants must be followed in more natural relevant chronic conditions. We previously showed morphological and biochemical responses in Lemna minor plants continuously exposed for 7days in a dose-rate dependent manner...
April 2017: Plant Science: An International Journal of Experimental Plant Biology
https://www.readbyqxmd.com/read/28223810/factors-associated-with-caregiver-burden-among-pharmacotherapy-treated-children-adolescents-with-adhd-in-the-caregiver-perspective-on-pediatric-adhd-survey-in-europe
#6
Moshe Fridman, Tobias Banaschewski, Vanja Sikirica, Javier Quintero, M Haim Erder, Kristina S Chen
BACKGROUND: Burden on caregivers of children/adolescents with attention-deficit/hyperactivity disorder (ADHD) is multidimensional, but incompletely understood. OBJECTIVE: To analyze caregiver burden across the concepts of work, social/family life, and parental worry/stress, in relation to selected contributing factors. METHODS: The online Caregiver Perspective on Pediatric ADHD survey was fielded in ten European countries. Analysis included children/adolescents (6-17 years) who were receiving/had received ADHD pharmacotherapy in the previous 6 months...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/28223745/intense-pulsed-light-alone-and-in-combination-with-erbium-yttrium-aluminum-garnet-laser-on-small-to-medium-sized-congenital-melanocytic-nevi-single-center-experience-based-on-retrospective-chart-review
#7
Mi So Lee, Hee Jin Jun, Sang Hyun Cho, Jeong Deuk Lee, Hei Sung Kim
BACKGROUND: Treatment of congenital melanocytic nevi (CMN) with intense pulsed light (IPL) has recently produced promising results. OBJECTIVE: To evaluate the clinical and histological outcomes of small-to-medium sized CMN treated with IPL alone and in combination with erbium: yttrium-aluminum-garnet (Er: YAG) laser. METHODS: We performed a retrospective chart review of 26 small-to-medium sized CMN treated as described above. The reduction in visible pigmentation, signs of recurrence and any adverse skin changes were evaluated by two independent clinicians...
February 2017: Annals of Dermatology
https://www.readbyqxmd.com/read/28222310/circulating-mirna-associated-with-posttraumatic-stress-disorder-in-a-cohort-of-military-combat-veterans
#8
Christiana G Martin, Hyungsuk Kim, Sijung Yun, Whitney Livingston, Joseph Fetta, Vincent Mysliwiec, Tristin Baxter, Jessica M Gill
Posttraumatic stress disorder (PTSD) affects many returning combat veterans, but underlying biological mechanisms remain unclear. In order to compare circulating micro RNA (miRNA) of combat veterans with and without PTSD, peripheral blood from 24 subjects was collected following deployment, and isolated miRNA was sequenced. PTSD was associated with 8 differentially expressed miRNA. Pathway analysis shows that PTSD is related to the axon guidance and Wnt signaling pathways, which work together to support neuronal development through regulation of growth cones...
January 31, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28220135/differential-gene-expression-analysis-in-polygonum-minus-leaf-upon-24-h-of-methyl-jasmonate-elicitation
#9
Reyhaneh Rahnamaie-Tajadod, Kok-Keong Loke, Hoe-Han Goh, Normah M Noor
Polygonum minus is an herbal plant that grows in Southeast Asian countries and traditionally used as medicine. This plant produces diverse secondary metabolites such as phenolic compounds and their derivatives, which are known to have roles in plant abiotic and biotic stress responses. Methyl jasmonate (MeJA) is a plant signaling molecule that triggers transcriptional reprogramming in secondary metabolism and activation of defense responses against many biotic and abiotic stresses. However, the effect of MeJA elicitation on the genome-wide expression profile in the leaf tissue of P...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28219827/the-intervening-role-of-urgency-on-the-association-between-childhood-maltreatment-ptsd-and-substance-related-problems
#10
Rebecca Mirhashem, Holley C Allen, Zachary W Adams, Katherine van Stolk-Cooke, Alison Legrand, Matthew Price
A range of risk factors lead to opioid use and substance-related problems (SRP) including childhood maltreatment, elevated impulsivity, and psychopathology. These constructs are highly interrelated such that childhood maltreatment is associated with elevated impulsivity and trauma-related psychopathology such as posttraumatic stress disorder (PTSD), and impulsivity-particularly urgency-and PTSD are related. Prior work has examined the association between these constructs and substance-related problems independently and it is unclear how these multi-faceted constructs (i...
February 10, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/28219153/-social-support-and-occupational-stress-relationship-analysis-of-1-413-train-drivers-in-a-railway-bureau
#11
G Z Gu, S F Yu, W H Zhou, H Wu, L Kang, R Chen
Objective: To investigate the social support status of train drivers. Methods: Using cluster sampling, a cross-sectional study was conducted in 1 413 male train drivers (including 301 passenger train drivers, 683 freight train drivers, 85 guest scheduling train drivers, 265 cargo adjustable drivers, and 79 high-speed train drivers) from a railway bureau depot. The survey included individual factors, social support, occupational stressors, strains, personalities, and coping strategy using occupational stress instruments and effort-reward imbalance questionnaire...
February 6, 2017: Zhonghua Yu Fang Yi Xue za Zhi [Chinese Journal of Preventive Medicine]
https://www.readbyqxmd.com/read/28219121/a-pilot-study-evaluation-of-psychosocial-competency-training-for-junior-physicians-working-in-oncology-and-hematology
#12
Stefanie Mache, Karin Vitzthum, Inka Hauschild, David Groneberg
BACKGROUND: This pilot and feasibility study evaluated a work-related self-care competency training in Oncology and Hematology Medicine for junior physicians working in Oncology and Hematology Medicine. METHODS: A pilot study was conducted with 80 physicians working in oncology and hematology hospital departments in Germany. Physicians were distributed to either the intervention group receiving competency training or a comparison group. The intervention took place in groups over a period of 12 weeks...
February 20, 2017: Psycho-oncology
https://www.readbyqxmd.com/read/28219078/mechanical-metamaterials-at-the-theoretical-limit-of-isotropic-elastic-stiffness
#13
J B Berger, H N G Wadley, R M McMeeking
A wide variety of high-performance applications require materials for which shape control is maintained under substantial stress, and that have minimal density. Bio-inspired hexagonal and square honeycomb structures and lattice materials based on repeating unit cells composed of webs or trusses, when made from materials of high elastic stiffness and low density, represent some of the lightest, stiffest and strongest materials available today. Recent advances in 3D printing and automated assembly have enabled such complicated material geometries to be fabricated at low (and declining) cost...
February 20, 2017: Nature
https://www.readbyqxmd.com/read/28218994/maternal-stress-and-psychological-distress-preconception-association-with-offspring-atopic-eczema-at-age-12-months
#14
S El-Heis, S R Crozier, E Healy, S M Robinson, N C Harvey, C Cooper, H M Inskip, J Baird, K M Godfrey
BACKGROUND: Perinatal maternal stress and low mood have been linked to offspring atopic eczema. OBJECTIVES: To examine the relation of maternal stress/mood with atopic eczema in the offspring, focusing particularly on stress/psychological distress preconception. METHODS: At recruitment in the UK Southampton Women's Survey, preconception maternal reports of perceived stress in daily living and the effect of stress on health were recorded; in a sub-sample psychological distress was assessed (12-item General Health Questionnaire)...
February 20, 2017: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28217499/factors-associated-with-high-stress-levels-in-adults-with-diabetes-mellitus-attending-a-tertiary-diabetes-care-center-chennai-tamil-nadu-india
#15
Muthappan Sendhilkumar, Jaya Prasad Tripathy, Anthony D Harries, Amol R Dongre, Mohan Deepa, Ashok Vidyulatha, Subramanian Poongothai, Ulaganathan Venkatesan, Ranjit Mohan Anjana, Viswanathan Mohan
OBJECTIVE: We aimed to determine perceived stress levels among adults aged >20 years with type 2 diabetes mellitus (DM) in a tertiary care diabetes center, Chennai, Tamil Nadu, India, assess their association with sociodemographic and clinical characteristics and assess the possible risk factors for stress and coping strategies. METHODS: A mixed-methods (triangulation design) study with quantitative methodology (survey) and qualitative methodology (interviews) was carried out...
January 2017: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28217095/endogenous-protein-interactome-of-human-udp-glucuronosyltransferases-exposed-by-untargeted-proteomics
#16
Michèle Rouleau, Yannick Audet-Delage, Sylvie Desjardins, Mélanie Rouleau, Camille Girard-Bock, Chantal Guillemette
The conjugative metabolism mediated by UDP-glucuronosyltransferase enzymes (UGTs) significantly influences the bioavailability and biological responses of endogenous molecule substrates and xenobiotics including drugs. UGTs participate in the regulation of cellular homeostasis by limiting stress induced by toxic molecules, and by controlling hormonal signaling networks. Glucuronidation is highly regulated at genomic, transcriptional, post-transcriptional and post-translational levels. However, the UGT protein interaction network, which is likely to influence glucuronidation, has received little attention...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28212942/activation-of-type-4-dopaminergic-receptors-in-the-prelimbic-area-of-medial-prefrontal-cortex-is-necessary-for-the-expression-of-innate-fear-behavior
#17
Macarena D Vergara, Victor N Keller, José A Fuentealba, Katia Gysling
The prelimbic area (PL) of the medial Prefrontal cortex (mPFC) is involved in the acquisition and expression of conditioned and innate fear. Both types of fear share several neuronal pathways. It has been documented that dopamine (DA) plays an important role in the regulation of aversive memories in the mPFC. The exposure to an aversive stimulus, such as the smell of a predator odor or the exposure to footshock stress is accompanied by an increase in mPFC DA release. Evidence suggests that the type 4 dopaminergic receptor (D4R) is the molecular target through which DA modulates fear expression...
February 14, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28212306/metabolic-effects-of-berries-with-structurally-diverse-anthocyanins
#18
John Overall, Sierra A Bonney, Mickey Wilson, Arnold Beermann, Mary H Grace, Debora Esposito, Mary Ann Lila, Slavko Komarnytsky
Overconsumption of energy dense foods and sedentary lifestyle are considered as major causes of obesity-associated insulin resistance and abnormal glucose metabolism. Results from both cohort studies and randomized trials suggested that anthocyanins from berries may lower metabolic risks, however these reports are equivocal. The present study was designed to examine effects of six berries with structurally diverse anthocyanin profiles (normalized to 400 µg/g total anthocyanin content) on development of metabolic risk factors in the C57BL/6 mouse model of polygenic obesity...
February 15, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28211130/cancer-survivors-activation-to-self-management-and-its-relationship-with-participation-in-paid-work-and-work-related-problems
#19
Pomme van Maarschalkerweerd, Jany Rademakers, Mieke Rijken
OBJECTIVE: This study aimed to explore cancer survivors' level of patient activation, i.e., their knowledge, skills and confidence for self-management, and to examine its relations to their participation in paid work and work-related problems. METHODS: 524 Dutch cancer survivors, 208 younger than 65 years, completed the Patient Activation Measure (PAM-13) and the RAND-36 General Health scale. Cancer survivors younger than 65 years also reported on their participation in paid work and work-related problems...
February 16, 2017: Psycho-oncology
https://www.readbyqxmd.com/read/28209171/integrated-strategy-for-in-vitro-characterization-of-a-bileaflet-mechanical-aortic-valve
#20
Francesca Maria Susin, Stefania Espa, Riccardo Toninato, Stefania Fortini, Giorgio Querzoli
BACKGROUND: Haemodynamic performance of heart valve prosthesis can be defined as its ability to fully open and completely close during the cardiac cycle, neither overloading heart work nor damaging blood particles when passing through the valve. In this perspective, global and local flow parameters, valve dynamics and blood damage safety of the prosthesis, as well as their mutual interactions, have all to be accounted for when assessing the device functionality. Even though all these issues have been and continue to be widely investigated, they are not usually studied through an integrated approach yet, i...
February 16, 2017: Biomedical Engineering Online
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