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https://www.readbyqxmd.com/read/28938176/genotypic-differences-in-physiological-and-biochemical-responses-to-salinity-stress-in-melon-cucumis-melo-l-plants-prospects-for-selection-of-salt-tolerant-landraces
#1
Behrooz Sarabi, Sahebali Bolandnazar, Nasser Ghaderi, Jaleh Ghashghaie
Melon (Cucumis melo L.) is one of the most important horticultural crops in Iran often cultivated in arid and semiarid regions of the country with salinity problems. The objective of this work was to better understand the mechanisms of physiological and biochemical responses to salinity stress of five Iranian melon landraces "Samsuri", "Kashan", "Khatouni", "Suski-e-Sabz", and "Ghobadlu" from different geographical origins, and "Galia" F1 cultivar. Plants were grown under greenhouse conditions and irrigated with half-strength Hoagland solution containing 0, 30, 60, or 90 mM NaCl for 60 days...
September 13, 2017: Plant Physiology and Biochemistry: PPB
https://www.readbyqxmd.com/read/28931831/hyperhomocysteinemia-alters-retinal-endothelial-cells-barrier-function-and-angiogenic-potential-via-activation-of-oxidative-stress
#2
Riyaz Mohamed, Isha Sharma, Ahmed S Ibrahim, Heba Saleh, Nehal M Elsherbiny, Sadanand Fulzele, Khaled Elmasry, Sylvia B Smith, Mohamed Al-Shabrawey, Amany Tawfik
Hyperhomocysteinemia (HHcy) is associated with several human visual disorders, such as diabetic retinopathy (DR) and age-related macular degeneration (AMD). Breakdown of the blood-retinal barrier (BRB) is linked to vision loss in DR and AMD. Our previous work revealed that HHcy altered BRB in retinal endothelial cells in vivo. Here we hypothesize that homocysteine (Hcy) alters retinal endothelial cell barrier function and angiogenic potential via activation of oxidative stress. Human retinal endothelial cells (HRECs) treated with and without different concentrations of Hcy showed a reduction of tight junction protein expression, increased FITC dextran leakage, decreased transcellular electrical resistance and increased angiogenic potential...
September 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28931004/the-logic-of-the-floral-transition-reverse-engineering-the-switch-controlling-the-identity-of-lateral-organs
#3
Jean-Louis Dinh, Etienne Farcot, Charlie Hodgman
Much laboratory work has been carried out to determine the gene regulatory network (GRN) that results in plant cells becoming flowers instead of leaves. However, this also involves the spatial distribution of different cell types, and poses the question of whether alternative networks could produce the same set of observed results. This issue has been addressed here through a survey of the published intercellular distribution of expressed regulatory genes and techniques both developed and applied to Boolean network models...
September 20, 2017: PLoS Computational Biology
https://www.readbyqxmd.com/read/28930451/a-biomimetic-stress-sensitive-hydrogel-controlled-by-dna-nanoswitches
#4
Swapneel R Deshpande, Roel Hammink, Frank H T Nelissen, Alan E Rowan, Hans A Heus
One of the most intriguing and important aspects of biological supramolecular materials is its ability to adapt macroscopic properties in response to environmental cues for controlling cellular processes. Recently, bulk matrix stiffness, in particular stress sensitivity, has been established as a key mechanical cue in cellular function and development. However, stress-stiffening capacity and the ability to control and exploit this key characteristic is relatively new to the field of biomimetic materials. In this work, DNA-responsive hydrogels, composed of semiflexible PIC polymers equipped with DNA cross-linkers, were engineered to create mimics of natural biopolymer networks that capture these essential elastic properties and can be controlled by external stimuli...
September 20, 2017: Biomacromolecules
https://www.readbyqxmd.com/read/28930172/rhein-induces-oxidative-stress-and-apoptosis-in-mouse-blastocysts-and-has-immunotoxic-effects-during-embryonic-development
#5
Chien-Hsun Huang, Wen-Hsiung Chan
Rhein, a glucoside chemical compound found in a traditional Chinese medicine derived from the roots of rhubarb, induces cell apoptosis and is considered to have high potential as an antitumor drug. Several previous studies showed that rhein can inhibit cell proliferation and trigger mitochondria-related or endoplasmic reticulum (ER) stress-dependent apoptotic processes. However, the side effects of rhein on pre- and post-implantation embryonic development remain unclear. Here, we show that rhein has cytotoxic effects on blastocyst-stage mouse embryos and induces oxidative stress and immunotoxicity in mouse fetuses...
September 20, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28929995/endocrinological-and-subjective-stress-responses-in-children-with-depressive-anxiety-or-externalizing-disorders
#6
Stephanie Stadelmann, Sonia Jaeger, Tina Matuschek, Yoon Ju Bae, Kai von Klitzing, Annette Maria Klein, Mirko Döhnert
In this study, we used a stress test to investigate endocrinological and subjective stress responses of 8- to 14-year-old children with internalizing or externalizing disorders and healthy controls. The sample (N = 170) consisted of clinical and community children. Parents were given a diagnostic interview to diagnose their children's psychiatric condition. We measured saliva cortisol and subjectively experienced arousal in children before and after the Trier Social Stress Test for Children. Children also rated their performance immediately after the stress test, and 1 hr later they rated their positive and negative thoughts about this stressful event...
September 20, 2017: Development and Psychopathology
https://www.readbyqxmd.com/read/28929242/impaired-working-memory-updating-affects-memory-for-emotional-and-non-emotional-materials-the-same-way-evidence-from-post-traumatic-stress-disorder-ptsd
#7
Vahid Nejati, Mohammad Ali Salehinejad, Azam Sabayee
Due to the limited capacity of working memory (WM), efficient suppression of no longer relevant memory contents (inhibition) and revising the current contents of the memory (updating) are crucial factors in memorizing. However, not every individual is able to do so; among them are post-traumatic stress disorder (PTSD) patients who seem to have trouble forgetting trauma-related materials, making their memory overloaded with irrelevant information. The present study assumes that the inability to forget in PTSD patients is due to the impaired updating function of WM and, therefore, suggests that these individuals have inferior WM function for both emotional and unemotional materials...
September 19, 2017: Cognitive Processing
https://www.readbyqxmd.com/read/28927291/differentially-conserved-transcriptomic-response-to-adversity-related-to-self-rated-health-in-the-multi-ethnic-study-of-atherosclerosis
#8
Pia Riestra, Samson Y Gebreab, Yongmei Liu, Ana V Diez Roux, Rumana R Khan, Amadou Gaye, Ruihua Xu, S K Davis
Self-rated health (SRH) is considered a strong indicator of well-being and clinical health status and has been linked to inflammatory markers. The objective of this work was to examine how self-rated physical health (SRPH) and mental health (SRMH) influence the immune system through the regulation of a stress-related gene expression profile known as the 'conserved transcriptional response to adversity' (CTRA), which involves the up-regulation of pro-inflammatory genes and down-regulation of genes involved in type I interferon (IFN) response and antibody synthesis...
January 1, 2017: Experimental Biology and Medicine
https://www.readbyqxmd.com/read/28926769/experimental-study-of-time-response-of-bending-deformation-of-bone-cantilevers-in-an-electric-field
#9
Huimin Kang, Zhende Hou, Qing-Hua Qin
Bone is a complex composite material with hierarchical structures and anisotropic mechanical properties. Bone also processes electromechanical properties, such as piezoelectricity and streaming potentials, which termed as stress generated potentials. Furthermore, the electrostrictive effect and flexoelectric effect can also affect electromechanical properties of the bone. In the present work, time responses of bending deflections of bone cantilever in an external electric field are measured experimentally to investigate bone's electromechanical behavior...
September 13, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28926758/some-aspects-of-the-iodine-metabolism-of-the-giant-kelp-macrocystis-pyrifera-phaeophyceae
#10
Teresa M Tymon, Eric P Miller, Jennifer L Gonzales, Andrea Raab, Frithjof C Küpper, Carl J Carrano
Despite its paramount role in the functioning of coastal ecosystems, relatively little is known about halogen metabolism in giant kelp (Macrocystis pyrifera). This is an important shortcoming given the potential implications for marine and atmospheric chemical processes in the wide distribution range of Macrocystis. The work presented here constitutes the first in depth investigation of the uptake, efflux, and of the physiological function of iodide in this important kelp species. Iodide uptake and efflux rates were measured in adult sporophytes of Macrocystis under normal and stressed (exogenous hydrogen peroxide and an elicitor-triggered oxidative burst) conditions...
September 8, 2017: Journal of Inorganic Biochemistry
https://www.readbyqxmd.com/read/28926000/the-bdnf-val66met-polymorphism-regulates-glucocorticoid-induced-corticohippocampal-remodeling-and-behavioral-despair
#11
M Notaras, X Du, J Gogos, M van den Buuse, R A Hill
The BDNF Val66Met polymorphism has been associated with sensitivity to stress and affective disorders. We therefore sought to model the inter-causality of these relationships under controlled laboratory conditions. We subjected humanized BDNF Val66Met (hBDNF(Val66Met)) transgenic mice to a history of stress, modeled by chronic late-adolescent corticosterone (CORT) exposure, before evaluating affective-related behavior using the forced-swim test (FST) in adulthood. While hBDNF(Met/Met) mice had a depression-like phenotype in the FST irrespective of CORT, hBDNF(Val/Val) wildtype mice had a resilient phenotype but developed an equally robust depressive-like phenotype following CORT...
September 19, 2017: Translational Psychiatry
https://www.readbyqxmd.com/read/28923056/physicians-perceptions-on-the-impact-of-telemedicine-on-recruitment-and-retention-in-underserved-areas-a-descriptive-study-in-senegal
#12
Birama Apho Ly, Ivy Lynn Bourgeault, Ronald Labonté, Mbayang Ndiaye Niang
BACKGROUND: Similar to many places, physicians in Senegal are unevenly distributed. Telemedicine is considered a potential solution to this problem. This study investigated the perceptions of Senegal's physicians of the impact of telemedicine on their recruitment to and retention in underserved areas. METHODS: We conducted individual interviews with a random sample of 60 physicians in Senegal, including 30 physicians working in public hospitals and 30 physicians working in district health centres between January and June 2014, as part of a mixed methods study...
September 18, 2017: Human Resources for Health
https://www.readbyqxmd.com/read/28921994/anisotropic-cracking-of-nanocrystal-superlattices
#13
Benjamin T Diroll, Xuedan Ma, Yaoting Wu, Christopher B Murray
The synthesis colloidal nanocrystals in non-polar organic solvents has led to exceptional size- and shape-control, enabling the formation of nanocrystal superlattices isostructural to atomic lattices built with nanocrystals rather than atoms. The long aliphatic ligands (e.g. oleic acid) used to achieve this control separate nanocrystals too far in the solid-state for most charge-transporting devices. Solid-state ligand exchange, which brings particles closer together and enhances conductivity, necessitates large changes in the total volume of the solid (compressive stress), which leads to film cracking...
September 18, 2017: Nano Letters
https://www.readbyqxmd.com/read/28919763/sociodemographic-variables-and-social-values-relationship-with-work-attendance-problems-in-brunei-public-and-private-sector-employees
#14
Lawrence Mundia, Salwa Mahalle, Rohani Matzin, Gamal Abdul Nasir Zakaria, Nor Zaiham Midawati Abdullah
OBJECTIVE: The study investigated the degree to which selected sociodemographic variables and social values were related to work-attendance problems in a random sample of 860 Brunei public- and private-sector employees and the nature of this relationship. MATERIALS AND METHODS: This quantitative study used the field-survey approach to administer research instruments directly to participants. This enabled the researchers to help participants who needed assistance in completing the measures properly, so as to increase the number of usable returns...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/28919553/social-evaluative-threat-with-verbal-performance-feedback-alters-neuroendocrine-response-to-stress
#15
Jenny M Phan, Ekaterina Schneider, Jeremy Peres, Olga Miocevic, Vanessa Meyer, Elizabeth A Shirtcliff
Laboratory stress tasks such as the Trier Social Stress Test (TSST) have provided a key piece to the puzzle for how psychosocial stress impacts the hypothalamic-pituitary-adrenal axis, other stress-responsive biomarkers, and ultimately wellbeing. These tasks are thought to work through biopsychosocial processes, specifically social evaluative threat and the uncontrollability heighten situational demands. The present study integrated an experimental modification to the design of the TSST to probe whether additional social evaluative threat, via negative verbal feedback about speech performance, can further alter stress reactivity in 63 men and women...
September 15, 2017: Hormones and Behavior
https://www.readbyqxmd.com/read/28918008/a-finite-element-study-on-the-mechanical-response-of-the-head-neck-interface-of-hip-implants-under-realistic-forces-and-moments-of-daily-activities-part-2
#16
Khosro Fallahnezhad, Hamidreza Farhoudi, Reza H Oskouei, Mark Taylor
A finite element model was developed to investigate the effect of loading regimes caused by various daily activities on the mechanical behaviour of the head-neck taper junction in modular hip replacements. The activities included stair up, stair down, sit to stand, stand to sit, one leg standing and knee bending. To present the real mechanical environment of the junction, in addition to the force components, the frictional moments produced by the frictional sliding of the head and cup were applied to a CoCr/CoCr junction having a 12/14 taper with a proximal mismatch angle of 0...
September 7, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28917581/an-engineering-insight-into-the-relationship-of-selective-cytoskeletal-impairment-and-biomechanics-of-hela-cells
#17
Daniele Borin, Luca Puzzi, Valentina Martinelli, Matteo Cibinel, Romano Lapasin, Orfeo Sbaizero
It is widely accepted that the pathological state of cells is characterized by a modification of mechanical properties, affecting cellular shape and viscoelasticity as well as adhesion behaviour and motility. Thus, assessing these parameters could represent an interesting tool to monitor disease development and progression, but also the effects of drug treatments. Since biomechanical properties of cells are strongly related to cytoskeletal architecture, in this work we extensively studied the effects of selective impairments of actin microfilaments and microtubules on HeLa cells through force-deformation curves and stress relaxation tests with atomic force microscopy...
September 8, 2017: Micron: the International Research and Review Journal for Microscopy
https://www.readbyqxmd.com/read/28917571/academy-of-dental-materials-guidance-resin-composites-part-ii-technique-sensitivity-handling-polymerization-dimensional-changes
#18
J L Ferracane, T J Hilton, J W Stansbury, D C Watts, N Silikas, N Ilie, S Heintze, M Cadenaro, R Hickel
OBJECTIVE: The objective of this work, commissioned by the Academy of Dental Materials, was to review and critically appraise test methods to characterize properties related to critical issues for dental resin composites, including technique sensitivity and handling, polymerization, and dimensional stability, in order to provide specific guidance to investigators planning studies of these properties. METHODS: The properties that relate to each of the main clinical issues identified were ranked in terms of their priority for testing, and the specific test methods within each property were ranked...
September 13, 2017: Dental Materials: Official Publication of the Academy of Dental Materials
https://www.readbyqxmd.com/read/28917154/neural-activation-in-stress-related-exhaustion-cross-sectional-observations-and-interventional-effects
#19
Hanna Malmberg Gavelin, Anna Stigsdotter Neely, Micael Andersson, Therese Eskilsson, Lisbeth Slunga Järvholm, Carl-Johan Boraxbekk
The primary purpose of this study was to investigate the association between burnout and neural activation during working memory processing in patients with stress-related exhaustion. Additionally, we investigated the neural effects of cognitive training as part of stress rehabilitation. Fifty-five patients with clinical diagnosis of exhaustion disorder were administered the n-back task during fMRI scanning at baseline. Ten patients completed a 12-week cognitive training intervention, as an addition to stress rehabilitation...
September 13, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28916949/the-latina-birth-weight-paradox-the-role-of-subjective-social-status
#20
Jill Fleuriet, Thankam Sunil
The purpose of this project was to quantitatively test differences in subjective social status scores between non-pregnant and pregnant women to determine the role of subjective social status in birth weight variation between Mexico-born and US-born Mexican-American women. Six hundred low-income pregnant and non-pregnant Mexican immigrant and Mexican-American women in south Texas were surveyed for subjective social status, depression, perceived social stress, parity, and pregnancy intendedness. Psychosocial health variables, parity, and pregnancy intendedness were included due to their significant associations with low birth weight...
September 15, 2017: Journal of Racial and Ethnic Health Disparities
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