keyword
https://read.qxmd.com/read/38461983/a-preliminary-assessment-on-spatial-prioritization-for-integrated-urban-flood-management-based-on-source-tracking-method
#1
JOURNAL ARTICLE
Peng Li, Fulin Li, Zongxue Xu, Pengyue Song, Sulin Song
With rapid urbanization and global climate change, the frequency of extreme rainfall and urban flooding has increased significantly, posing a serious threat to human life and property safety. Integrated urban flood management is an important component of urban planning that combines various infrastructure to effectively manage and utilize stormwater. This is essential for dealing with urban inundation disasters. Despite the implementation of numerous engineering and non-engineering measures, flood mitigation still faces a challenge in identifying spatial prioritization due to the lack of consideration for regional spatial connectivity...
March 8, 2024: Science of the Total Environment
https://read.qxmd.com/read/38422677/antimicrobial-activity-of-eugenol-and-carvacrol-against-salmonella-enterica-and-e-coli-o157-h7-in-falafel-paste-at-different-storage-temperatures
#2
JOURNAL ARTICLE
Amin N Olaimat, Murad A Al-Holy, Tareq M Osaili, Mahmoud H Abughoush, Anas A Al-Nabulsi, Maysa Alawneh, Lamees Deseh, Bushra Abazeed, Raghdah Shqair, Sawsan Mutlaq, Mutamed Ayyash, Richard A Holley
The objectives of the current study were: i) to investigate the antimicrobial activity of 0.125, 0.250 and 0.50 % (7.54, 15.08 and 30.17 mmol/Kg of eugenol) and (8.15, 16.31, and 33.61 mmol/Kg of carvacrol) against S. enterica and E. coli O157:H7 in falafel paste (FP) stored at 4, 10 or 25 °C for 10 d; and ii) to study the sensory properties of fried falafel treated with eugenol and carvacrol. S. enterica grew well in untreated falafel (control) samples at 10 and 25 °C, while E...
February 27, 2024: International Journal of Food Microbiology
https://read.qxmd.com/read/38388376/pediatrician-and-parental-evaluation-of-child-neurodevelopment-at-2-years-of-age
#3
JOURNAL ARTICLE
Giulia Segre, Antonio Clavenna, Elisa Roberti, Francesca Scarpellini, Massimo Cartabia, Chiara Pandolfini, Valeria Tessarollo, Ilaria Costantino, Maurizio Bonati
BACKGROUND: The early identification of infants with a risk for neurodevelopmental disorders in the first few years of life is essential for better developmental outcomes. Screenings should be carried out by combining the family pediatricians' and parents' perspectives, the two fundamental sources of information on children's health. The present study has three aims: (a) to test the feasibility of parent-report instruments to detect warning signs in their children's development; (b) to ascertain whether there is an agreement between the family pediatricians' (FP) clinical judgments of warning signs and the parental perceptions; (c) to determine whether there is a link between parents' distress and child development...
February 22, 2024: BMC Pediatrics
https://read.qxmd.com/read/38363362/technology-in-medicine-improving-clinical-documentation
#4
JOURNAL ARTICLE
Derek J Baughman, Paul A Botros, Abdul Waheed
The association between electronic health record (EHR) documentation and physician burnout is well-known. A combination of insufficient time to complete tasks, clinical documentation burden, and electronic inbox overload comprises the definition of documentation-related burnout. Burnout mitigation strategies related to clinical documentation include use of targeted EHR training for documentation, use of medical scribes, and institutional documentation redesign. Mitigation strategies related to electronic inbox overload include assigning designated administrative time for inbox management, tailoring of message content to decrease length, and a team-based approach to clinical workflows...
February 2024: FP Essentials
https://read.qxmd.com/read/38363361/technology-in-medicine-remote-patient-monitoring
#5
JOURNAL ARTICLE
Derek J Baughman, Paul A Botros, Abdul Waheed
Remote patient monitoring (RPM) provides real-time clinical patient data to the medical team. The foundational element of RPM is communication, including data processing and integration in the electronic health record and communication of data between patients and clinicians. Patient portals are integral to this communication and their use can result in improved health outcomes and patient safety. Patient portals promote engagement of patients in their care, increase access to the medical team, and integrate RPM system data...
February 2024: FP Essentials
https://read.qxmd.com/read/38363360/technology-in-medicine-telemedicine
#6
JOURNAL ARTICLE
Derek J Baughman, Paul A Botros, Abdul Waheed
Telemedicine is defined as the provision of clinical services via telephone or video and is a type of telehealth. Telehealth is defined as the use of electronic information and telecommunications technologies for the delivery of health care, health education, and health information. During the COVID-19 pandemic, telemedicine availability and use of telehealth care significantly increased. The integral role of telemedicine during this time prompted the unprecedented integration of telehealth as a quasi-standard of care...
February 2024: FP Essentials
https://read.qxmd.com/read/38363359/technology-in-medicine-optimizing-electronic-health-records
#7
JOURNAL ARTICLE
Derek J Baughman
Electronic health record (EHR) systems have transformed the medical industry. Despite their known benefits, their implementation has resulted in new digital administrative tasks and responsibilities for physicians. This increase in administrative burden has been shown to contribute to physician burnout. Most sources of EHR-related burnout can be categorized into three groups: poor usability, excessive time spent in the EHR, and inefficient workflows. Evidence-based interventions for EHR-related burnout focus on training and education, which improve efficiency in EHR use and may reduce burnout...
February 2024: FP Essentials
https://read.qxmd.com/read/38363358/technology-in-medicine-foreword
#8
JOURNAL ARTICLE
Ryan D Kauffman
No abstract text is available yet for this article.
February 2024: FP Essentials
https://read.qxmd.com/read/38332201/crosstalk-between-cd64-mhcii-macrophages-and-cd4-t-cells-drives-joint-pathology-during-chikungunya
#9
JOURNAL ARTICLE
Fok-Moon Lum, Yi-Hao Chan, Teck-Hui Teo, Etienne Becht, Siti Naqiah Amrun, Karen Ww Teng, Siddesh V Hartimath, Nicholas Kw Yeo, Wearn-Xin Yee, Nicholas Ang, Anthony M Torres-Ruesta, Siew-Wai Fong, Julian L Goggi, Evan W Newell, Laurent Renia, Guillaume Carissimo, Lisa Fp Ng
Communications between immune cells are essential to ensure appropriate coordination of their activities. Here, we observed the infiltration of activated macrophages into the joint-footpads of chikungunya virus (CHIKV)-infected animals. Large numbers of CD64+ MHCII+ and CD64+ MHCII- macrophages were present in the joint-footpad, preceded by the recruitment of their CD11b+ Ly6C+ inflammatory monocyte precursors. Recruitment and differentiation of these myeloid subsets were dependent on CD4+ T cells and GM-CSF...
February 8, 2024: EMBO Molecular Medicine
https://read.qxmd.com/read/38328041/yellow-and-oxidation-resistant-derivatives-of-a-monomeric-superfolder-gfp
#10
Fernando M Valbuena, Adam H Krahn, Sherzod A Tokamov, Annie C Greene, Richard G Fehon, Benjamin S Glick
Fluorescent proteins (FPs) are essential tools in biology. The utility of FPs depends on their brightness, photostability, efficient folding, monomeric state, and compatibility with different cellular environments. Despite the proliferation of available FPs, derivatives of the originally identified Aequorea victoria GFP often show superior behavior as fusion tags. We recently generated msGFP2, an optimized monomeric superfolder variant of A. victoria GFP. Here, we describe two derivatives of msGFP2. The monomeric variant msYFP2 is a yellow superfolder FP with high photostability...
January 26, 2024: bioRxiv
https://read.qxmd.com/read/38323895/nudix-hydrolase-wvnudx24-is-involved-in-borneol-biosynthesis-in-wurfbainia-villosa
#11
JOURNAL ARTICLE
Peng Yang, Yuan-Xia Chen, Tian-Tian Wang, Xue-Shuang Huang, Ruo-Ting Zhan, Jin-Fen Yang, Dong-Ming Ma
Borneol, camphor, and bornyl acetate are highly promising monoterpenoids widely used in medicine, flavor, food, and chemical applications. Bornyl diphosphate (BPP) serves as a common precursor for the biosynthesis of these monoterpenoids. Although bornyl diphosphate synthase (BPPS) that catalyzes the cyclization of geranyl diphosphate (GPP) to BPP has been identified in multiple plants, the enzyme responsible for the hydrolysis of BPP to produce borneol has not been reported. Here, we conducted in vitro and in vivo functional characterization to identify the Nudix hydrolase WvNUDX24 from W...
February 7, 2024: Plant Journal
https://read.qxmd.com/read/38313535/a-salt-bridge-and-disulfide-bond-within-the-lassa-virus-fusion-domain-are-required-for-the-initiation-of-membrane-fusion
#12
JOURNAL ARTICLE
Hallie N Pennington, Daniel Birtles, Zoe W Shi, Jinwoo Lee
Infection with Lassa virus (LASV), an Old-World arenavirus that is endemic to West Africa, causes Lassa fever, a lethal hemorrhagic fever. Delivery of LASV's genetic material into the host cell is an integral component of its lifecycle. This is accomplished via membrane fusion, a process initiated by a hydrophobic sequence known as the fusion domain (FD). The LASV FD (G260 -N295 ) consists of two structurally distinct regions: an N-terminal fusion peptide (FP: G260 -T274 ) and an internal fusion loop (FL: C279 -N295 ) that is connected by a short linker region (P275 -Y278 )...
January 30, 2024: ACS Omega
https://read.qxmd.com/read/38297197/research-on-the-control-rate-of-hypertension-under-family-physician-contracted-service
#13
JOURNAL ARTICLE
Yiping Zheng, Yuqing Liu, Dongyu Xue, Zhao Shang, Baoquan Zhang, Yue Dai
BACKGROUND: Hypertension is one of the global public health problems. Family physician-contracted service (FPCS) is widely used in the health management of hypertension patients in China. The purpose of this study was to assess the effect of FPCS on hypertension control. METHODS: PubMed, Web of Science, the Cochrane Library, China National Knowledge Network, Chinese Scientific and Technological Journal Database (CQVIP), and Wanfang Database were searched for randomized controlled trials related to family physician-contracted service and hypertension control effect, and meta-analysis was performed on the literature meeting the inclusion criteria...
January 31, 2024: BMC Prim Care
https://read.qxmd.com/read/38270149/mechanistic-understanding-of-the-modes-of-ca-2-ion-binding-to-the-sars-cov-1-fusion-peptide-and-their-role-in-the-dynamics-of-host-membrane-penetration
#14
JOURNAL ARTICLE
Juliana Debrito Carten, George Khelashvili, Miya K Bidon, Marco R Straus, Tiffany Tang, Javier A Jaimes, Gary R Whittaker, Harel Weinstein, Susan Daniel
The SARS-CoV-1 spike glycoprotein contains a fusion peptide (FP) segment that mediates the fusion of the viral and host cell membranes. Calcium ions are thought to position the FP optimally for membrane insertion by interacting with negatively charged residues in this segment (E801, D802, D812, E821, D825, and D830); however, which residues bind to calcium and in what combinations supportive of membrane insertion are unknown. Using biological assays and molecular dynamics studies, we have determined the functional configurations of FP-Ca2+ binding that likely promote membrane insertion...
January 25, 2024: ACS Infectious Diseases
https://read.qxmd.com/read/38260675/a-comparison-of-field-portable-x-ray-fluorescence-fp-xrf-and-inductively-coupled-plasma-mass-spectrometry-icp-ms-for-analysis-of-metals-in-the-soil-and-ambient-air
#15
Kelsey Schmidt, Daniel Autenrieth, Raja Nagisetty
When analyzing metal concentrations in the soil and ambient air, accurate and reliable results are essential. Inductively coupled plasma mass spectrometry (ICP-MS) is considered the benchmark analytical method for environmental soil and air filter samples containing metals. Field portable X-ray fluorescence (FP XRF) can provide more timely results with lower ongoing costs, but the results are not as accurate as ICP-MS. The primary goal of this study was to find an optimal method to maximize the level of agreement between FP XRF results and ICP-MS results when analyzing metal concentrations in soil and ambient air samples in a U...
January 11, 2024: Research Square
https://read.qxmd.com/read/38256983/review-on-frontal-polymerization-behavior-for-thermosetting-resins-materials-modeling-and-application
#16
REVIEW
Tingting Luo, Yating Ma, Xiaoyu Cui
The traditional curing methods for thermosetting resins are energy-inefficient and environmentally unfriendly. Frontal polymerization (FP) is a self-sustaining process relying on the exothermic heat of polymerization. During FP, the external energy input (such as UV light input or heating) is only required at the initial stage to trigger a localized reaction front. FP is regarded as the rapid and energy-efficient manufacturing of polymers. The precise control of FP is essential for several manufacturing technologies, such as 3D printing, depending on the materials and the coupling of thermal transfer and polymerization...
January 8, 2024: Polymers
https://read.qxmd.com/read/38233936/association-between-diet-quality-and-risk-of-stunting-among-school-aged-children-in-schistosoma-mansoni-endemic-area-of-western-kenya-a-cross-sectional-study
#17
JOURNAL ARTICLE
Madoka Kishino, Azumi Hida, Evans A Chadeka, Manabu Inoue, Mayuko Osada-Oka, Sohkichi Matsumoto, Sammy M Njenga, Shinjiro Hamano, Sachiyo Nagi
BACKGROUND: Healthy eating habits are essential for improving nutritional status and strengthening immunity against infectious diseases. This study examined the relationship between diet quality and stunting in school-aged children in an infectious disease-endemic area of western Kenya. METHODS: This cross-sectional study included 260 school-aged children (age 9-17 years) enrolled in primary schools in Mbita Sub-county, western Kenya. The nutritional status was assessed using anthropometric measurements...
January 17, 2024: Tropical Medicine and Health
https://read.qxmd.com/read/38232611/is-controlled-ovarian-stimulation-safe-in-patients-with-hormone-receptor-positive-breast-cancer-receiving-neoadjuvant-chemotherapy
#18
REVIEW
C Benvenuti, L Laot, T Grinda, M Lambertini, B Pistilli, M Grynberg
INTRODUCTION: Controlled ovarian stimulation (COS) for oocyte/embryo cryopreservation is the method of choice for fertility preservation (FP) in young patients diagnosed with early-stage breast cancer (eBC). Nevertheless, some challenges still question its role, particularly in the neoadjuvant setting, where concerns arise about potential delay in the onset of anticancer treatment, and in hormone receptor-positive (HR+) disease, as cancer cells may proliferate under the estrogenic peak associated with stimulation...
January 16, 2024: ESMO Open
https://read.qxmd.com/read/38227453/cardiovascular-disease-inflammatory-and-infectious-heart-conditions
#19
JOURNAL ARTICLE
Robert L Gauer, Joel M Guess
Acute pericarditis, the most common inflammatory heart condition, typically is caused by viral infections. Patients have sharp chest pain that improves when leaning forward. Electrocardiogram typically shows widespread ST-segment elevation; echocardiogram may show pericardial effusion; and levels of inflammatory markers may be elevated. Colchicine plus nonsteroidal anti-inflammatory drugs are first-line treatment. Patients with fever, elevated inflammatory marker levels, or pericardial effusion should be hospitalized...
January 2024: FP Essentials
https://read.qxmd.com/read/38227452/cardiovascular-disease-other-common-arrhythmias
#20
JOURNAL ARTICLE
Joel M Guess, Robert L Gauer
Premature atrial contractions (PACs) occur in nearly all individuals. Although typically asymptomatic, they can cause palpitations. PACs previously were considered benign, but there is increasing recognition that frequent PACs are associated with developing atrial fibrillation. After potentially reversible causes (eg, electrolyte abnormalities, hyperthyroidism) are eliminated, symptomatic PACs can be treated with beta blockers; some patients are candidates for ablation. Premature ventricular contractions (PVCs) also are common, occurring in more than two-thirds of the population...
January 2024: FP Essentials
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