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https://www.readbyqxmd.com/read/28619727/rna-seq-implicates-deregulation-of-the-immune-system-in-the-pathogenesis-of-diverticulitis
#1
Kathleen M Schieffer, Christine S Choi, Scott Emrich, Leonard Harris, Sue Deiling, Dipti M Karamchandani, Anna Salzberg, Yuka I Kawasawa, Gregory S Yochum, Walter A Koltun
Individuals with diverticula or outpouchings of the colonic mucosa and submucosa through the colonic wall have diverticulosis, which is usually asymptomatic. In 10-25% of individuals, the diverticula become inflamed, resulting in diverticulitis. Very little is known about the pathophysiology or gene regulatory pathways involved in the development of diverticulitis. To identify these pathways, we deep sequenced RNAs isolated from full-thickness sections of sigmoid colon from diverticulitis patients and control individuals...
June 15, 2017: American Journal of Physiology. Gastrointestinal and Liver Physiology
https://www.readbyqxmd.com/read/28616930/-a-study-of-etiology-classification-of-minor-stroke-based-on-toast-and-asco-systems
#2
Jie Zhou, Yang Zhang, Yi-Jia Guo, Li He
OBJECTIVES: To investigate the differences in the etiology between minor stroke and non-minor stroke based on TOAST and ASCO systems, and to guide the early intervention for minor stroke. METHODS: We retrospectively analyzed the patients with acute ischemic stroke admitted to our department from July 2012 to July 2014. We sub-typed minor stroke patients and non-minor stroke patients in etiology using Trial of Org 10172 in Acute Stroke Treatment (TOAST) and ASCO (A for atherosclerosis, S for small vessel disease, C for Cardiac source, O for other cause) systems respectively to investigate the difference of etiology between the two groups...
May 2017: Sichuan da Xue Xue Bao. Yi Xue Ban, Journal of Sichuan University. Medical Science Edition
https://www.readbyqxmd.com/read/28602688/quality-control-in-cone-beam-computed-tomography-cbct-efomp-estro-iaea-protocol-summary-report
#3
Hugo de Las Heras Gala, Alberto Torresin, Alexandru Dasu, Osvaldo Rampado, Harry Delis, Irene Hernández Girón, Chrysoula Theodorakou, Jonas Andersson, John Holroyd, Mats Nilsson, Sue Edyvean, Vesna Gershan, Lama Hadid-Beurrier, Christopher Hoog, Gregory Delpon, Ismael Sancho Kolster, Primož Peterlin, Julia Garayoa Roca, Paola Caprile, Costas Zervides
The aim of the guideline presented in this article is to unify the test parameters for image quality evaluation and radiation output in all types of cone-beam computed tomography (CBCT) systems. The applications of CBCT spread over dental and interventional radiology, guided surgery and radiotherapy. The chosen tests provide the means to objectively evaluate the performance and monitor the constancy of the imaging chain. Experience from all involved associations has been collected to achieve a consensus that is rigorous and helpful for the practice...
June 8, 2017: Physica Medica: PM
https://www.readbyqxmd.com/read/28595269/identification-of-a-rare-lamb4-variant-associated-with-familial-diverticulitis-through-exome-sequencing
#4
Joel L Coble, Kathryn Sheldon, Feng Yue, Tarik Salameh, Leonard Harris, Sue Deiling, Francesca Ruggiero, Melanie Eshelman, Gregory S Yochum, Walter A Koltun, Glenn S Gerhard, James R Broach
Diverticulitis is a chronic disease of the colon in which diverticuli, or outpouching through the colonic wall, become inflamed. Although recent observations suggests that genetic factors may play a significant role in diverticulitis, few genes have yet been implicated in disease pathogenesis and familial cases are uncommon. Here, we report results of whole exome sequencing performed on members from a single multi-generational family with early onset diverticulitis in order to identify a genetic component of the disease...
June 8, 2017: Human Molecular Genetics
https://www.readbyqxmd.com/read/28589864/efficient-detection-of-viral-transmissions-with-next-generation-sequencing-data
#5
Inna Rytsareva, David S Campo, Yueli Zheng, Seth Sims, Sharma V Thankachan, Cansu Tetik, Jain Chirag, Sriram P Chockalingam, Amanda Sue, Srinivas Aluru, Yury Khudyakov
BACKGROUND: Hepatitis C is a major public health problem in the United States and worldwide. Outbreaks of hepatitis C virus (HCV) infections associated with unsafe injection practices, drug diversion, and other exposures to blood are difficult to detect and investigate. Molecular analysis has been frequently used in the study of HCV outbreaks and transmission chains; helping identify a cluster of sequences as linked by transmission if their genetic distances are below a previously defined threshold...
May 24, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28573265/a-rare-case-of-malignant-melanoma-of-the-mandible-%C3%A2-ct-and-mri-findings
#6
Ichiro Ogura, Yoshihiko Sasaki, Ayako Kameta, Mikiko Sue, Takaaki Oda
Malignant melanoma of the mandibular gingiva is extremely rare. It is a malignant tumour of melanocytes or their precursor cells, and often misinterpreted as a benign pigmented process. A few reports have described computed tomography (CT) and magnetic resonance imaging (MRI) findings of malignant melanoma in the oral cavity. We report a rare case of malignant melanoma of the mandible and the related CT and MRI findings. Soft tissue algorithm contrast-enhanced CT showed an expansile mass and irregular destruction of alveolar bone in the right side of the mandibular molar area...
2017: Chinese Journal of Dental Research
https://www.readbyqxmd.com/read/28557757/influenza-vaccine-effectiveness-against-pediatric-deaths-2010-2014
#7
Brendan Flannery, Sue B Reynolds, Lenee Blanton, Tammy A Santibanez, Alissa O'Halloran, Peng-Jun Lu, Jufu Chen, Ivo M Foppa, Paul Gargiullo, Joseph Bresee, James A Singleton, Alicia M Fry
BACKGROUND AND OBJECTIVES: Surveillance for laboratory-confirmed influenza-associated pediatric deaths since 2004 has shown that most deaths occur in unvaccinated children. We assessed whether influenza vaccination reduced the risk of influenza-associated death in children and adolescents. METHODS: We conducted a case-cohort analysis comparing vaccination uptake among laboratory-confirmed influenza-associated pediatric deaths with estimated vaccination coverage among pediatric cohorts in the United States...
May 2017: Pediatrics
https://www.readbyqxmd.com/read/28536687/abdominal-and-pelvic-actinomycosis-due-to-longstanding-intrauterine-device-a-slow-and-devastating-infection
#8
Evelyn Sue Nakahira, Linda Ferreira Maximiano, Fabiana Roberto Lima, Edson Yassushi Ussami
Actinomycosis is a chronic or subacute bacterial infection characterized by large abscess formation, caused mainly by the gram-positive non-acid-fast, anaerobic, or microaerophilic/capnophilic, obligate parasites bacteria from the Actinomyces genus. Although pelvic inflammatory disease is an entity associated with the longstanding use of intrauterine devices (IUDs), actinomycosis is not one of the most frequent infections associated with IUDs. We present the case of a 43-year-old female patient who was referred to the emergency facility because of a 20-day history of abdominal pain with signs of peritoneal irritation...
January 2017: Autopsy & case reports
https://www.readbyqxmd.com/read/28536112/necrotic-cutaneous-vasculitic-skin-lesions-a-case-of-atypical-henoch-sch%C3%A3-nlein-purpura-in-a-child-with-heterozygosity-for-factor-v-leiden
#9
Sacha Dhanjal, Anja Saso, Despina Eleftheriou, Sue Laurent
No abstract text is available yet for this article.
May 22, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28526905/effectiveness-of-acellular-dermal-matrix-on-autologous-split-thickness-skin-graft-in-treatment-of-deep-tissue-defect-esthetic-subjective-and-objective-evaluation
#10
Yoo Jung Lee, Myong Chul Park, Dong Ha Park, Hyung Min Hahn, Sue Min Kim, Il Jae Lee
BACKGROUND: A split-thickness skin graft (STSG) is performed to cover a large full-thickness skin defect. Esthetic and functional deficits can result, and many studies have sought to overcome them. This study compared the effectiveness of the acellular dermal matrix (ADM) graft and STSG concerning esthetic and functional effectiveness of ADM on scar quality. METHODS: Of the patients who underwent anterolateral thigh free flap from 2011 to 2015, patients who received skin graft only (n = 10) or skin graft with ADM (n = 20) for coverage of the donor site were enrolled...
May 19, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28513893/relationship-between-iodine-levels-and-papillary-thyroid-carcinoma-a-systematic-review-and-meta-analysis
#11
REVIEW
Joon-Hyop Lee, Yunji Hwang, Ra-Yeong Song, Jin Wook Yi, Hyeong Won Yu, Su-Jin Kim, Young Jun Chai, June Young Choi, Kyu Eun Lee, Sue K Park
BACKGROUND: Iodine excess has been suggested as an exogenous risk factor of papillary thyroid cancer (PTC). We performed a systematic review and meta-analysis to assess the relationship between iodine exposure measured in various forms and PTC prevalence. METHODS: We searched MEDLINE, Embase, and the Cochrane Library for case-control studies on iodine and PTC published up to December 2015. Exposure to iodine was compared between PTC and control groups. RESULTS: From the 16 selected studies, the odds ratio (OR) for the overall effect size between high iodine exposure and PTC risk was 1...
May 17, 2017: Head & Neck
https://www.readbyqxmd.com/read/28503389/rosai-dorfman-disease-of-the-breast
#12
Eileen E Delaney, Anne Larkin, Sue MacMaster, Ali Sakhdari, Carolynn M DeBenedectis
Rosai-Dorfman disease (also known as sinus histiocytosis with massive lymphadenopathy) is a rare benign proliferative disorder of histiocytes that typically involves the lymph nodes and can also involve extranodal sites. Rosai-Dorfman disease confined to the breast is extremely rare, but important to recognize as it can mimic malignancy. We present the case of a 63-year-old woman who presented with a palpable breast lump that was highly suspicious for malignancy based on mammogram and ultrasound appearance...
April 11, 2017: Curēus
https://www.readbyqxmd.com/read/28493767/nursing-a-critically-ill-tetanus-patient-in-an-intensive-care-unit-in-zambia
#13
Chris Carter, Sue Viveash
The global incidence of tetanus has been gradually reducing. Improvements in vaccination and health education programmes and the World Health Organization campaign to eradicate maternal and neonatal tetanus have all resulted in fewer presentations globally. Unfortunately, tetanus mortality remains a significant problem for many developing countries, owing to inadequate vaccination programmes or to conflict or humanitarian disasters during which vaccination programmes are stopped or there is sporadic cover. This case study explores the care of a tetanus patient in an intensive care unit in Zambia, a lower-middle-income country in sub-Saharan Africa...
May 11, 2017: British Journal of Nursing: BJN
https://www.readbyqxmd.com/read/28490390/development-and-evaluation-of-acceptance-and-commitment-therapy-delivered-by-psychologists-and-non-psychologists-in-an-nhs-community-adult-mental-health-service-a-preliminary-analysis
#14
Thomas Richardson, Lorraine Bell, Helen Bolderston, Sue Clarke
BACKGROUND: Previous studies have demonstrated that acceptance and commitment therapy (ACT) is effective for depression and may be useful for complex transdiagnostic clients. AIMS: To conduct a preliminary evaluation of whether ACT is feasible and effective when delivered by psychologists and non-psychologists for complex clients in a National Health Service (NHS) community mental health service for adults. METHOD: Staff were trained in ACT and conducted one-to-one therapy with clients...
May 11, 2017: Behavioural and Cognitive Psychotherapy
https://www.readbyqxmd.com/read/28489216/the-role-of-surgery-in-the-management-of-women-with-gestational-trophoblastic-disease
#15
Lana DE Lourdes Aguiar Lima, Lílian Padron, Raphael Câmara, Sue Yazaki Sun, Jorge Rezende, Antônio Braga
The Gestational Trophoblastic Disease includes an interrelated group of diseases originating from placental tissue, with distinct behaviors concerning local invasion and metastasis. The high sensitivity of the serial dosages of human chorionic gonadotrophin, combined with advances in chemotherapy treatment, have made gestational trophoblastic neoplasia curable, most often through chemotherapy. However, surgery remains of major importance in the management of patients with gestational trophoblastic disease, improving their prognosis...
January 2017: Revista do Colégio Brasileiro de Cirurgiões
https://www.readbyqxmd.com/read/28487308/pancreatic-metastasis-from-an-osseous-solitary-fibrous-tumour
#16
Jennifer Sue Colvin, Gareth Morris-Stiff, Michael Cruise, Andrei Purysko
A 73-year-old man presented with a right-sided chest wall mass that showed an epitheloid neoplasm with mild cytologic atypia on core needle biopsy. He underwent surgical resection, and final pathology revealed solitary fibrous tumour/hemangiopericytoma with negative margins. Three years after surgical resection, the patient presented with fatigue, abdominal pain, weight loss and mildly elevated liver function tests. Further workup revealed a 1.2 cm hypervascular mass in the neck of the pancreas. This case report summarises the surgical treatment and outcomes for a patient who presented with this rare tumour...
May 9, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28471003/australian-validation-of-the-cancer-of-the-prostate-risk-assessment-post-surgical-score-to-predict-biochemical-recurrence-after-radical-prostatectomy
#17
Kerri Beckmann, Michael O'Callaghan, Andrew Vincent, David Roder, Jeremy Millar, Sue Evans, John McNeil, Kim Moretti
BACKGROUND: The Cancer of the Prostate Risk Assessment Post-Surgical (CAPRA-S) score is a simple post-operative risk assessment tool predicting disease recurrence after radical prostatectomy, which is easily calculated using available clinical data. To be widely useful, risk tools require multiple external validations. We aimed to validate the CAPRA-S score in an Australian multi-institutional population, including private and public settings and reflecting community practice. METHODS: The study population were all men on the South Australian Prostate Cancer Clinical Outcomes Collaborative Database with localized prostate cancer diagnosed during 1998-2013, who underwent radical prostatectomy without adjuvant therapy (n = 1664)...
May 4, 2017: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/28467223/haddenham-easywrap-the-latest-innovation-in-the-management-of-lymphoedema
#18
Natalie Lee, Sue Lawrence
The use of velcro compression wrapping devices in the management of lymphoedema and chronic oedema is not a new concept. Wraps have been available for many years and are being used widely in clinic and community settings where bandaging or traditional compression garments are not suitable. Furthermore, they are becoming more common when treating venous disease, patients with wounds and lipoedema. The aim of this article is to introduce the reader and clinician to the new Haddenham easywrap and to demonstrate why it is different to any other velcro wrapping device available...
May 1, 2017: British Journal of Community Nursing
https://www.readbyqxmd.com/read/28464035/modelling-risk-adjusted-variation-in-length-of-stay-among-australian-and-new-zealand-icus
#19
Lahn D Straney, Andrew A Udy, Aidan Burrell, Christoph Bergmeir, Sue Huckson, D James Cooper, David V Pilcher
PURPOSE: Comparisons between institutions of intensive care unit (ICU) length of stay (LOS) are significantly confounded by individual patient characteristics, and currently there is a paucity of methods available to calculate risk-adjusted metrics. METHODS: We extracted de-identified data from the Australian and New Zealand Intensive Care Society (ANZICS) Adult Patient Database for admissions between January 1 2011 and December 31 2015. We used a mixed-effects log-normal regression model to predict LOS using patient and admission characteristics...
2017: PloS One
https://www.readbyqxmd.com/read/28463862/making-a-case-for-entrustable-professional-activities-for-nurse-practitioners-in-emergency-care
#20
K Sue Hoyt, Elda G Ramirez, Jean A Proehl
No abstract text is available yet for this article.
April 2017: Advanced Emergency Nursing Journal
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