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https://www.readbyqxmd.com/read/28224774/comparison-of-luminex-nxtag-respiratory-pathogen-panel-and-xtag-respiratory-viral-panel-fast-version-2-for-the-detection-of-respiratory-viruses
#1
Chun Kiat Lee, Hong Kai Lee, Christopher Wei Siong Ng, Lily Chiu, Julian Wei Tze Tang, Tze Ping Loh, Evelyn Siew Chuan Koay
Owing to advancements in molecular diagnostics, recent years have seen an increasing number of laboratories adopting respiratory viral panels to detect respiratory pathogens. In December 2015, the NxTAG respiratory pathogen panel (NxTAG RPP) was approved by the United States Food and Drug Administration. We compared the clinical performance of this new assay with that of the xTAG respiratory viral panel (xTAG RVP) FAST v2 using 142 clinical samples and 12 external quality assessment samples. Discordant results were resolved by using a laboratory-developed respiratory viral panel...
May 2017: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/28220090/adaptation-and-validation-of-a-chinese-version-of-patient-health-engagement-scale-for-patients-with-chronic-disease
#2
Yaying Zhang, Guendalina Graffigna, Andrea Bonanomi, Kai-Chow Choi, Serena Barello, Pan Mao, Hui Feng
The Patient Health Engagement Scale (PHE-s) was designed to assess the emotional and psychological attitudes of patients' engagement along their healthcare management journey. The aim of this study was to validate a culturally adapted Chinese version of the PHE-s (CPHE-s). Three hundred and seventy-seven participants were recruited from eight community health centers in a sample of patients with chronic disease in Hunan Province, China. The original Italian PHE-s was translated into Mandarin Chinese using a standardized forward-backward translation...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28217540/correlating-the-clinical-assessment-of-impacted-mandibular-third-molars-with-panoramic-radiograph-and-intraoral-periapical-radiograph
#3
P Vani Priya, Fazil A Nasyam, M Ramprasad, Narendra V Penumatsa, Syed Akifuddin, Sandeep
AIMS AND OBJECTIVES: This study was conducted to compare the clinical assessment of impacted third molars of mandible with panaromic radiograph (OPG) and intraoral periapical radiograph (IOPA) and to assess the efficacy of IOPA and. Moreover, we corroborated the OPG and IOPA findings of impacted mandiblar third molar root apex to inferior alveolar canal. MATERIALS AND METHODS: A total of 200 patients with pericoronitis were examined who were indicated for surgical extraction, among which 50 patients were selected for the study...
December 2016: Journal of International Society of Preventive & Community Dentistry
https://www.readbyqxmd.com/read/28214436/impact-of-child-maltreatment-on-meaning-in-life-in-psychiatric-patients
#4
Sébastien Weibel, Sonia Vidal, Emilie Olié, Roland Hasler, Catherine Torriani, Paco Prada, Philippe Courtet, Sébastien Guillaume, Nader Perroud, Philippe Huguelet
Child maltreatment (CM) worsens prognosis and quality of life in several psychiatric conditions. Meaning in life is a construct which relates to the sense of purpose that one can perceive in life, and is a key aspect of recovery in psychiatric patients. The lasting impact of CM on meaning in life and its mediating variables have not been studied in patients with chronic persistent psychiatric conditions. One hundred and sixty-six patients with bipolar disorder (N=35), psychotic disorder (N=73), anorexia nervosa (N=30) or borderline personality disorder (N=28) were assessed for meaning in life (revised version of the Life Regard Index (LRI-R)), for CM (Childhood Trauma Questionnaire (CTQ)) and for internalized/externalized psychopathology...
February 13, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28211548/the-33-item-hypomania-checklist-hcl-33-a-study-of-the-consistency-between-self-and-external-assessments-in-polish-bipolar-patients
#5
Dorota Łojko, Dominika Dudek, Jules Angst, Marcin Siwek, Michał Michalak, Janusz Rybakowski
OBJECTIVES: The Hypomania Checklist (HCL) has become an important tool for the assessment of hypomanic symptoms in patients with mood disorders and in the general population. The HCL-33 scale, containing 33 symptom items, is a new instrument which, in addition to the self-administered questionnaire, has a version for external rating. The aim of this study is to evaluate the consistency between the self - and external assessments using the HCL-33 in Polish patients with bipolar disorder...
December 23, 2016: Psychiatria Polska
https://www.readbyqxmd.com/read/28202735/a-higher-order-theory-of-emotional-consciousness
#6
Joseph E LeDoux, Richard Brown
Emotional states of consciousness, or what are typically called emotional feelings, are traditionally viewed as being innately programmed in subcortical areas of the brain, and are often treated as different from cognitive states of consciousness, such as those related to the perception of external stimuli. We argue that conscious experiences, regardless of their content, arise from one system in the brain. In this view, what differs in emotional and nonemotional states are the kinds of inputs that are processed by a general cortical network of cognition, a network essential for conscious experiences...
February 15, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28194657/eq-5d-and-the-euroqol-group-past-present-and-future
#7
REVIEW
Nancy J Devlin, Richard Brooks
Over the period 1987-1991 an inter-disciplinary five-country group developed the EuroQol instrument, a five-dimensional three-level generic measure subsequently termed the 'EQ-5D'. It was designed to measure and value health status. The salient features of its development and its consolidation and expansion are discussed. Initial expansion came, in particular, in the form of new language versions. Their development raised translation and semantic issues, experience with which helped feed into the design of two further instruments, the EQ-5D-5L and the youth version EQ-5D-Y...
February 13, 2017: Applied Health Economics and Health Policy
https://www.readbyqxmd.com/read/28190638/long-term-toxicity-and-health-related-quality-of-life-after-single-fraction-high-dose-rate-brachytherapy-boost-and-hypofractionated-external-beam-radiotherapy-for-intermediate-risk-prostate-cancer
#8
N Shahid, A Loblaw, H T Chung, P Cheung, E Szumacher, C Danjoux, R Sankreacha, L Zhang, A Deabreu, A Mamedov, G Morton
AIMS: To report health-related quality of life (HRQOL) and toxicity in prostate cancer patients treated with single-fraction high dose rate (HDR) brachytherapy boost and external beam radiotherapy (EBRT). MATERIALS AND METHODS: Patients with intermediate-risk prostate cancer were accrued to a phase II clinical trial of 15 Gy HDR boost and EBRT to a dose of 37.5 Gy in 15 fractions. HRQOL (Expanded Prostate Cancer Index Composite [EPIC]), urinary symptoms (International Prostate Symptom Score [IPSS]), erectile function (International Index of Erectile Function [IIEF]) and toxicity (Common Terminology Criteria for Adverse Events [CTCAE], version 3...
February 9, 2017: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/28188293/asymmetric-configurations-in-a-reengineered-homodimer-reveal-multiple-subunit-communication-pathways-in-protein-allostery
#9
Maria Fe Lanfranco, Fernanda Gárate, Ashton J Engdahl, Rodrigo A Maillard
Many allosteric proteins form homo-oligomeric complexes to regulate a biological function. In homo-oligomers, subunits establish communication pathways that are modulated by external stimuli like ligand binding. A challenge for dissecting the communication mechanisms in homo-oligomers is identifying intermediate liganded states, which are typically transiently populated. However, their identities provide the most mechanistic information on how ligand-induced signals propagate from bound to empty subunits. Here, we dissected the directionality and magnitude of subunit communication in a reengineered, single-chain version of the homodimeric transcription factor cAMP Receptor Protein (CRPSC)...
February 10, 2017: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/28186935/external-validation-of-the-probability-of-repeated-admission-pra-risk-prediction-tool-in-older-community-dwelling-people-attending-general-practice-a-prospective-cohort-study
#10
Emma Wallace, Ronald McDowell, Kathleen Bennett, Tom Fahey, Susan M Smith
OBJECTIVES: Emergency admission is associated with the potential for adverse events in older people and risk prediction models are available to identify those at highest risk of admission. The aim of this study was to externally validate and compare the performance of the Probability of repeated admission (Pra) risk model and a modified version (incorporating a multimorbidity measure) in predicting emergency admission in older community-dwelling people. SETTING: 15 general practices (GPs) in the Republic of Ireland...
November 14, 2016: BMJ Open
https://www.readbyqxmd.com/read/28185338/distinguishing-subtypes-of-extrinsic-motivation-among-people-with-mild-to-borderline-intellectual-disability
#11
N Frielink, C Schuengel, P Embregts
BACKGROUND: According to self-determination theory, motivation is ordered in types, including amotivation, extrinsic motivation and intrinsic motivation. Self-determination theory defines four subtypes of extrinsic motivation: external motivation, introjected motivation, identified motivation and integrated motivation. Although it has been argued theoretically that the different types of motivation are universally applicable, Reid et al. () proposed a dichotomy of broad subtypes of extrinsic motivation for people with intellectual disability (ID) due to their cognitive limitations...
February 10, 2017: Journal of Intellectual Disability Research: JIDR
https://www.readbyqxmd.com/read/28182540/symbiosis-based-alternative-learning-multi-swarm-particle-swarm-optimization
#12
Ben Niu, Huali Huang, Lijing Tan, Qiqi Duan
Inspired by the ideas from the mutual cooperation of symbiosis in natural ecosystem, this paper proposes a new variant of PSO, named Symbiosis-based Alternative Learning Multi-swarm Particle Swarm Optimization (SALMPSO). A learning probability to select one exemplar out of the center positions, the local best position, and the historical best position including the experience of internal and external multiple swarms, is used to keep the diversity of the population. Two different levels of social interaction within and between multiple swarms are proposed...
January 2017: IEEE/ACM Transactions on Computational Biology and Bioinformatics
https://www.readbyqxmd.com/read/28169826/-the-coping-strategies-of-patients-with-malignant-wound-160-an-analytic-study
#13
Nelly Espanet, Sébastien Colson, Karine Baumstarck, Francette Futo, Julien Mancini, Sébastien Salas
<ce:para>Introduction/Background : evolution of the cancerous disease sometimes results in externalization of the tumor to the skin, creating a malignant wound. Limited data describe the coping strategies that individuals will use to deal with this situation.</ce:para><ce:para>Aim : the main objective is to determine the different strategies of adaptations used by patients with malignant wounds, and links with their clinical and sociodemographic characteristics. Secondary objective is to document body image of these individuals...
July 5, 2016: Recherche en Soins Infirmiers
https://www.readbyqxmd.com/read/28168598/brain-activity-underlying-negative-self-and-other-perception-in-adolescents-the-role-of-attachment-derived-self-representations
#14
Martin Debbané, Deborah Badoud, David Sander, Stephan Eliez, Patrick Luyten, Pascal Vrtička
One of teenagers' key developmental tasks is to engage in new and meaningful relationships with peers and adults outside the family context. Attachment-derived expectations about the self and others in terms of internal attachment working models have the potential to shape such social reorientation processes critically and thereby influence adolescents' social-emotional development and social integration. Because the neural underpinnings of this developmental task remain largely unknown, we sought to investigate them by functional magnetic resonance imaging...
February 6, 2017: Cognitive, Affective & Behavioral Neuroscience
https://www.readbyqxmd.com/read/28166169/spanish-translation-cross-cultural-adaptation-and-validation-of-the-american-academy-of-orthopaedic-surgeons-foot-and-ankle-outcomes-questionnaire-in-mexican-americans-with-traumatic-foot-and-ankle-injuries
#15
Boris A Zelle, Ben S Francisco, James P Bossman, Roberto J Fajardo, Mohit Bhandari
BACKGROUND: Hispanics represent the largest minority group within the US population accounting for an estimated 55.4 million individuals. Enrolling Hispanics into clinical outcome studies is important in order for study populations to be externally valid and representative of the US population. Inclusion of Mexican-Americans in clinical studies is frequently limited by the lack of validated outcome measures. The goal of this study was to validate a Spanish version of the American Academy of Orthopaedic Surgeons Foot and Ankle Outcomes Questionnaire (AAOS-FAOQ) in Mexican-Americans with traumatic foot and ankle injuries...
January 24, 2017: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/28162877/humeral-version-in-reverse-shoulder-arthroplasty-affects-impingement-in-activities-of-daily-living
#16
Andreas Kontaxis, Xiang Chen, Julien Berhouet, Daniel Choi, Timothy Wright, David M Dines, Russell F Warren, Lawrence V Gulotta
BACKGROUND: Impingement after reverse shoulder arthroplasty (RSA) has been correlated with implant design and surgical techniques. Previous studies suggested that humeral retroversion can reduce impingement and increase external rotation range of motion (ROM). The purpose of this study was to determine how humeral version affects impingement in activities of daily living (ADLs). MATERIALS AND METHODS: A single surgeon performed virtual RSA on 30 arthritic shoulders that were reconstructed from preoperative computed tomography scans...
February 2, 2017: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/28159800/a-revised-framingham-stroke-risk-profile-to-reflect-temporal-trends
#17
Carole Dufouil, Alexa S Beiser, Leslie A McClure, Philip A Wolf, Christophe Tzourio, Virginia J Howard, Andrew J Westwood, Jayandra J Himali, Lisa M Sullivan, Hugo J Aparicio, Margaret Kelly-Hayes, Karen Ritchie, Carlos S Kase, Aleksandra Pikula, Jose R Romero, Ralph B D'Agostino, Cécilia Samieri, Ramachandran S Vasan, Genevieve Chêne, George Howard, Sudha Seshadri
BACKGROUND: -Age-adjusted stroke incidence has decreased over the past 50 years, likely due to changes in the prevalence and impact of various stroke risk factors. An updated version of the Framingham Stroke Risk Profile (FSRP) might better predict current risks in the Framingham Heart Study (FHS) and other cohorts. We compared the accuracy of the standard (Old), and of a revised (New) version of the FSRP in predicting the risk of all-stroke and ischemic stroke, and validated this new FSRP in two external cohorts, the 3 Cities (3C) and REGARDS studies...
February 3, 2017: Circulation
https://www.readbyqxmd.com/read/28156516/template-based-high-dose-rate-endobronchial-brachytherapy-for-palliation-of-previously-irradiated-obstructive-lung-lesions
#18
Hsienchang Chiu, Michael Ryan Folkert
: 174 Background: Local progression after external beam radiation therapy (RT) for lung cancer may result in clinical compromise from bleeding and/or airway obstruction, and additional RT may be precluded by radiation tolerance. High-dose-rate (HDR) endobronchial brachytherapy (EBT) is an effective salvage treatment for airway obstruction and/or bleeding, but requires significant time and resources; planning and treatment are performed bronchoscopically under anesthesia. We sought to reduce procedure and anesthesia time for EBT through template-based planning...
October 9, 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28154094/use-of-a-3-item-short-form-version-of-the-barthel-index-for-use-in-stroke-systematic-review-and-external-validation
#19
Rachael L MacIsaac, Myzoon Ali, Martin Taylor-Rowan, Helen Rodgers, Kennedy R Lees, Terence J Quinn
BACKGROUND AND PURPOSE: There may be a potential to reduce the number of items assessed in the Barthel Index (BI), and shortened versions of the BI have been described. We sought to collate all existing short-form BI (SF-BI) and perform a comparative validation using clinical trial data. METHODS: We performed a systematic review across multidisciplinary electronic databases to find all published SF-BI. Our validation used the VISTA (Virtual International Stroke Trials Archive) resource...
February 2, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28149366/relationships-between-movements-of-the-lower-limb-joints-and-the-pelvis-in-open-and-closed-kinematic-chains-during-a-gait-cycle
#20
Zdenek Svoboda, Miroslav Janura, Patrik Kutilek, Eva Janurova
Lots of athletic skills performed during practice or competition are initiated by the legs, where athletes either walk or run prior to executing specific skills. Kinematic chains are used to describe the relationships between body segments and joints during movement. The aim of this study was to determine the relationships between movements of lower limb segments and the pelvis in open and closed kinematic chains while walking. The experimental group consisted of 32 males (age 23.3 ± 2.5 years, body mass 78...
June 1, 2016: Journal of Human Kinetics
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