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https://www.readbyqxmd.com/read/29035192/bacillus-cereus-bacteremia-with-central-nervous-system-involvement-a-neuropathological-study
#1
Jean Philippe Brouland, Nathalie Sala, Selin Tusgul, Caterina Rebecchini, Enikö Kovari
Bacillus cereus is a widely-distributed, gram-positive or variable, rod-shaped bacterium frequently considered a contaminant in clinical specimens. It is recognized as a potential pathogen inducing self-limiting emetic or diarrheal food poisoning or localized infection in immunocompetent patients. True B. cereus bacteremia is uncommon and mainly observed in fragile patients, notably in immunocompromised individuals. We report clinical, radiological, and pathological findings of a 64-year-old patient with a history of acute myeloid leukemia who initially presented a fever while neutropenic after the induction of a second cycle of chemotherapy...
October 16, 2017: Clinical Neuropathology
https://www.readbyqxmd.com/read/29034091/phenotypic-and-genotypic-characterization-of-antibiotic-resistance-of-methicillin-resistant-staphylococcus-aureus-isolated-from-hospital-food
#2
Farhad Safarpoor Dehkordi, Hasan Gandomi, Afshin Akhondzadeh Basti, Ali Misaghi, Ebrahim Rahimi
BACKGROUND: Pathogenic biotypes of the Methicillin-resistant Staphylococcus aureus (MRSA) strains are considered to be one of the major cause of food-borne diseases in hospitals. The present investigation was done to study the pattern of antibiotic resistance and prevalence of antibiotic resistance genes of different biotypes of the MRSA strains isolated from various types of hospital food samples. METHODS: Four-hundred and eighty-five raw and cooked hospital food samples were cultured and MRSA strains were identified using the oxacillin and cefoxitin disk diffusion tests and mecA-based PCR amplification...
2017: Antimicrobial Resistance and Infection Control
https://www.readbyqxmd.com/read/29033364/-recurrent-cystisis-no-medicine-preventive-means
#3
J Armelle
OBJECTIVE: To estimate from the literature review, the interest of hygienic and behavioural measures and the use of food supplements (herbal) to prevent female urinary tract infection. METHODS: Pubmed research was focused on the efficiency of prophylactic measures in recurrent cystisis management. RESULTS: Due to many predisposing factors such as anatomical charasteristics, hydration and lifestyle, cystisis is more common in female subjects than in male...
October 12, 2017: Progrès en Urologie
https://www.readbyqxmd.com/read/29032651/complete-genome-sequence-of-salmonella-enterica-subsp-enterica-serovar-typhimurium-st1120-isolated-from-swine-feces-in-korea
#4
Seongok Kim, Eunsuk Kim, Soyeon Park, Tae-Wook Hahn, Hyunjin Yoon
Salmonella enterica subsp. enterica serovar Typhimurium, one of the most common food-borne pathogens, is transmitted mainly through contaminated food derived from infected animals. In this study, S. Typhimurium ST1120, an isolate from pig feces in Korea, was subjected to whole genome analysis to understand its genomic features associated with virulence. The genome of ST1120 was found to have a circular chromosome of 4,855,001 bp (GC content 52.2%) and a plasmid of 6,863 bp (GC content 46.0%). This chromosome was predicted to have 4,558 open reading frames (ORFs), 17 pseudogenes, 22 rRNA genes, and 86 tRNA genes...
October 14, 2017: Journal of Microbiology and Biotechnology
https://www.readbyqxmd.com/read/29030459/household-triclosan-and-triclocarban-effects-on-the-infant-and-maternal-microbiome
#5
Jessica V Ribado, Catherine Ley, Thomas D Haggerty, Ekaterina Tkachenko, Ami S Bhatt, Julie Parsonnet
In 2016, the US Food and Drug Administration banned the use of specific microbicides in some household and personal wash products due to concerns that these chemicals might induce antibiotic resistance or disrupt human microbial communities. Triclosan and triclocarban (referred to as TCs) are the most common antimicrobials in household and personal care products, but the extent to which TC exposure perturbs microbial communities in humans, particularly during infant development, was unknown. We conducted a randomized intervention of TC-containing household and personal care products during the first year following birth to characterize whether TC exposure from wash products perturbs microbial communities in mothers and their infants...
October 13, 2017: EMBO Molecular Medicine
https://www.readbyqxmd.com/read/29030448/prevalence-and-antimicrobial-resistance-of-enterococci-isolated-from-retail-meats-in-the-united-states-2002-2014
#6
Gregory H Tyson, Epiphanie Nyirabahizi, Emily Crarey, Claudine Kabera, Claudia Lam, Crystal Rice-Trujillo, Patrick F McDermott, Heather Tate
Bacteria of the genus Enterococcus are important human pathogens that are frequently resistant to a number of clinically important antibiotics. They are also used as a marker of animal fecal contamination of human foods, and are employed as sentinel organisms for tracking trends in resistance to antimicrobials with gram-positive activity. As part of the National Antimicrobial Resistance Monitoring System (NARMS), we evaluated several retail meat commodities for the presence of enterococci from 2002-2014, finding 92...
October 13, 2017: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/29030192/polyvinyl-alcohol-sodium-alginate-integrated-silver-nanoparticles-as-probable-solution-for-decontamination-of-microbes-contaminated-water
#7
M A Abu-Saied, Tarek H Taha, Nehal M El-Deeb, Elsayed E Hafez
It is well known that the pathogenic multidrug resistant microbes are highly distributed and transferred to human through contaminated food and water. Advanced technologies have been developed for controlling these microbes using synthesized nanoparticles. In this study, bio-synthesized silver nanoparticles were prepared, characterized and integrated with two synthetic and natural polymers. The polymers-silver nanoparticles were characterized using SEM, FTIR and mechanical properties of the membrane synthesized from either polymers with/without nanosilver...
October 10, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29029084/penicillin-binding-protein-encoded-by-pbp4-is-involved-in-mediating-copper-stress-in-listeria-monocytogenes
#8
Cameron Parsons, Ben Costolo, Phillip Brown, Sophia Kathariou
Listeria monocytogenes raises major food safety and public health concerns due its potential for severe foodborne disease and persistent colonization of food processing facilities. Copper is often employed to control pathogens in agriculture and is increasingly used in healthcare facilities, but mechanisms mediating tolerance of L. monocytogenes to copper remain poorly understood. A mariner-based mutant library of L. monocytogenes 2011L-2858, implicated in the 2011 listeriosis outbreak via whole cantaloupe, was screened for growth at sublethal levels of copper yielding mutant G2B4 with decreased copper tolerance...
October 4, 2017: FEMS Microbiology Letters
https://www.readbyqxmd.com/read/29028576/bioelectrochromic-hydrogel-for-fast-antibiotic-susceptibility-testing
#9
Ferran Pujol-Vila, Jiri Dietvorst, Laura Gall-Mas, María Díaz-González, Núria Vigués, Jordi Mas, Xavier Muñoz-Berbel
Materials science offers new perspectives in the clinical analysis of antimicrobial sensitivity. However, a biomaterial with the capacity to respond to living bacteria has not been developed to date. We present an electrochromic iron(III)-complexed alginate hydrogel sensitive to bacterial metabolism, here applied to fast antibiotic-susceptibility determination. Bacteria under evaluation are entrapped -and pre-concentrated- in the hydrogel matrix by oxidation of iron (II) ions to iron (III) and in situ formation of the alginate hydrogel in less than 2min and in soft experimental conditions (i...
September 6, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/29028568/virulence-genotypes-and-antimicrobial-susceptibility-patterns-of-arcobacter-butzleri-isolated-from-seafood-and-its-environment
#10
Srinu Rathlavath, Vandita Kohli, Asem Sanjit Singh, Manjusha Lekshmi, Gayatri Tripathi, Sanath Kumar, Binaya Bhusan Nayak
Arcobacter butzleri is an emerging pathogen isolated from animals, food and the environment. In this study, 147 A. butzleri isolated from seafood and the coastal environment were tested for the presence of ten putative virulence genes (cadF, cj1349, ciaB, mviN, pldA, tlyA, hecA, hecB, irgA, iroE) and antimicrobial susceptibilities. Majority of the isolates harbored mviN (100%), cj1349 (97.2%), ciaB (95.9%), tlyA (91.8%), pldA (91.1%) and cadF (89.7%). Lower detection rates were observed for hecA (10.8%), hecB (19%), iroE (12...
October 3, 2017: International Journal of Food Microbiology
https://www.readbyqxmd.com/read/29022388/our-gut-microbiota-a-long-walk-to-homeostasis
#11
L M T Dicks, J Geldenhuys, L S Mikkelsen, E Brandsborg, H Marcotte
The microbiome of the human gastrointestinal tract (GIT) consists of billions of bacteria, fungi and viruses, of which bacteria play the most important role in nutrition, immune development, production of vitamins and maintaining a well-balanced (homeostatic) microbial population. Many papers have been published on the microbiota in the human GIT, but little is known about the first group of bacteria that colonises an infant. The intestinal tract of an unborn is, despite general belief, not sterile, but contains bacteria that have been transferred from the mother...
October 12, 2017: Beneficial Microbes
https://www.readbyqxmd.com/read/29020146/trends-in-pricing-and-generic-competition-within-the-oral-antibiotic-drug-market-in-the-united-states
#12
Jonathan D Alpern, Lei Zhang, William M Stauffer, Aaron S Kesselheim
Background: In recent years, many older, generic drugs have increased substantially in price, including numerous antibiotics. We sought to analyze recent price changes and extent of generic competition within a cohort of commonly prescribed off-patent oral antibiotics. Methods: We extracted oral antibiotics recommended for common outpatient conditions within the Infectious Disease Society of America Practice Guidelines. We determined all Food and Drug Administration (FDA)-approved manufacturers for each formulation and strength in 2013 and 2016, and the yearly National Average Drug Acquisition Cost (NADAC) price between 2013 to 2016...
July 23, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29019312/widespread-distribution-of-mcr-1-bearing-bacteria-in-the-ecosystem-2015-to-2016
#13
Kaichao Chen, Edward Wai-Chi Chan, Miaomiao Xie, Liangwei Ye, Ning Dong, Sheng Chen
The recently discovered colistin resistance-encoding element, mcr-1, adds to the list of mobile resistance genes whose products rapidly erode the antimicrobial efficacy of not only the commonly used antibiotics, but also the last line agents of carbapenems and colistin. The relative prevalence of mcr-1-bearing strains in various ecological niches including 1,371 food samples, 480 animal faecal samples, 150 human faecal samples and 34 water samples was surveyed using a novel in-house method. Bacteria bearing mcr-1 were commonly detected in water (71% of samples), animal faeces (51%), food products (36%), and exhibited stable carriage in 28% of human subjects surveyed...
September 2017: Euro Surveillance: Bulletin Européen sur les Maladies Transmissibles, European Communicable Disease Bulletin
https://www.readbyqxmd.com/read/29018787/cesarean-section-formula-feeding-and-infant-antibiotic-exposure-separate-and-combined-impacts-on-gut-microbial-changes-in-later-infancy
#14
Farzana Yasmin, Hein Min Tun, Theodore Brian Konya, David S Guttman, Radha S Chari, Catherine J Field, Allan B Becker, Piush J Mandhane, Stuart E Turvey, Padmaja Subbarao, Malcolm R Sears, James A Scott, Irina Dinu, Anita L Kozyrskyj
Established during infancy, our complex gut microbial community is shaped by medical interventions and societal preferences, such as cesarean section, formula feeding, and antibiotic use. We undertook this study to apply the significance analysis of microarrays (SAM) method to quantify changes in gut microbial composition during later infancy following the most common birth and postnatal exposures affecting infant gut microbial composition. Gut microbiota of 166 full-term infants in the Canadian Healthy Infant Longitudinal Development birth cohort were profiled using 16S high-throughput gene sequencing...
2017: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/28993363/rare-postoperative-complication-clostridium-perfringens-septic-shock-following-elective-abdominal-surgery
#15
Michael Bath, Mark McKelvie, Khalid Canna
Postoperative infections are one of the most common complications in general surgery, and while rates have reduced with the routine administration of perioperative antibiotics, around 5% of patients undergoing a surgical procedure will develop an infective complication.(1) The Gram-positive, obligate anaerobe, Clostridium perfringens, is a well-known pathogen that forms part of both the environmental and gastrointestinal flora.(2) While more commonly associated with food poisoning, anaerobic cellulitis and traumatic gas gangrene, rare cases of spontaneous non-traumatic gas gangrene of abdominal viscera have also been recorded...
October 9, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28990821/enrichment-broth-for-the-detection-of-campylobacter-jejuni-and-campylobacter-coli-in-fresh-produce-and-poultry
#16
Youmi Jo, Hye-Min Oh, Yohan Yoon, Sun-Young Lee, Ji-Hyoung Ha, Won-Il Kim, Hwang-Yong Kim, Sanghyun Han, Se-Ri Kim
Although campylobacteriosis caused by Campylobacter jejuni and Campylobacter coli has been increasingly reported worldwide owing to the consumption of contaminated poultry and fresh produce, the current detection protocols are not selective enough to inhibit unspecific microbes other than these pathogens. Five antibiotics were separately added to Bolton broth, and the survival rates of 18 Campylobacter spp. and 79 non-Campylobacter spp. were evaluated. The survival rate of the non-Campylobacter spp. was the lowest in Bolton broth with rifampin (6...
October 9, 2017: Journal of Food Protection
https://www.readbyqxmd.com/read/28990114/clinical-guidance-for-managing-statin-and-antimicrobial-drug-drug-interactions
#17
REVIEW
Leigh Anne Hylton Gravatt, Rachel W Flurie, Estela Lajthia, Dave L Dixon
PURPOSE OF REVIEW: This review discusses potential drug-drug interactions between statins and antimicrobials and provides clinician's guidance on how to manage these interactions. RECENT FINDINGS: In addition to statin utilization increasing in recent years, there is greater emphasis on using moderate to high-intensity statin doses. Statin-related adverse effects are often dose-dependent; therefore, patients may be at increased risk. Antimicrobial use has also increased in recent years, and various efforts have been implemented to ensure appropriate use of antimicrobials...
October 9, 2017: Current Atherosclerosis Reports
https://www.readbyqxmd.com/read/28986269/quantitative-proteomic-analysis-reveals-that-chemotaxis-is-involved-in-chlortetracycline-resistance-of-aeromonas-hydrophila
#18
Wanxin Li, Farman Ali, Qilan Cai, Zujie Yao, Lina Sun, Wenxion Lin, Xiangmin Lin
In recent years, Aeromonas hydrophila, which has been classified as a food borne pathogen, has presented with increased levels of antibiotic resistance, with the mechanisms of this resistance being poorly understood. In this study, iTRAQ coupled mass spectrometry was employed to compare differentially expressed proteins in chlortetracycline (CTC) resistant A. hydrophila relative to a control strain. Result showed that a total of 234 differential proteins including 151 down-regulated and 83 up-regulated were identified in chlortetracycline resistance strain...
October 3, 2017: Journal of Proteomics
https://www.readbyqxmd.com/read/28984427/knowledge-gaps-and-research-priorities-in-staphylococcus-aureus-mastitis-control
#19
P Rainard, G Foucras, J R Fitzgerald, J L Watts, G Koop, J R Middleton
This study assessed knowledge gaps and suggested research priorities in the field of Staphylococcus aureus mastitis. Staphylococcus aureus infecting the mammary gland remains a major problem to the dairy industry worldwide because of its pathogenicity, contagiousness, persistence in the cow environment, colonization of skin or mucosal epithelia, and the poor curing efficacy of treatments. Staphylococcus aureus also constitutes a threat to public health due to food safety and antibiotic usage issues and the potential for bidirectional transmission of strains between humans and dairy animals (cows and small ruminants)...
October 6, 2017: Transboundary and Emerging Diseases
https://www.readbyqxmd.com/read/28970228/expression-of-a-peptidoglycan-hydrolase-from-lytic-bacteriophages-atu_ph02-and-atu_ph03-triggers-lysis-of-agrobacterium-tumefaciens
#20
Hedieh Attai, Jeanette Rimbey, George P Smith, Pamela J B Brown
In order to provide food security, innovative approaches to preventing plant disease are currently being explored. Here, we demonstrate that lytic bacteriophages and phage lysis proteins are effective at triggering lysis of the phytopathogen Agrobacterium tumefaciens Phages Atu_ph02 and Atu_ph03 were isolated from wastewater and induce lysis of C58-derived strains of A. tumefaciens Co-inoculation of A. tumefaciens with phage onto potato discs limits tumor formation. The genomes of Atu_ph02 and Atu_ph03 are nearly identical and ∼42% identical to T7 supercluster phages...
September 29, 2017: Applied and Environmental Microbiology
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