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https://www.readbyqxmd.com/read/28934824/acid-fastness-of-histoplasma-in-surgical-pathology-practice
#1
Madhu Rajeshwari, Immaculata Xess, Mehar Chand Sharma, Deepali Jain
BACKGROUND: Histoplasmosis (HP) is diagnosed by visualizing intracellular microorganisms in biopsy and/or culture. Periodic-acid Schiff (PAS) and Gomori methenamine silver (GMS) staining methods are routinely used for identification. The acid-fast property of Histoplasma was identified decades ago, but acid-fast staining has not been practiced in current surgical pathology. Awareness of the acid-fast property of Histoplasma, which is due to mycolic acid in the cell wall, is important in distinguishing Histoplasma from other infective microorganisms...
September 2017: Journal of Pathology and Translational Medicine
https://www.readbyqxmd.com/read/28934818/effects-of-zinc-alpha2-glycoprotein-on-lipid-metabolism-of-liver-in-high-fat-diet-induced-obese-mice
#2
Guoqiang Fan, Yu Qiao, Shixing Gao, Jun Guo, Ruqian Zhao, Xiaojing Yang
Zinc alpha2 glycoprotein (ZAG) is a new type of adipokine involved in adipose tissue mobilization, however, little is known about its lipid metabolism effect in liver. Therefore, we investigated the effects of ZAG in the regulation of hepatic lipid accumulation. Mice were randomly divided into two groups; one was fed a normal diet and another was fed a high-fat diet for eight weeks to establish obesity model. After that, the normal diet group was divided into ND (injection of pcDNA3.1) and NDZ (injection of ZAG recombinant plasmid) and the high-fat diet group was divided into HF (injection of pcDNA3...
September 21, 2017: Hormone and Metabolic Research, Hormon- und Stoffwechselforschung, Hormones et Métabolisme
https://www.readbyqxmd.com/read/28934699/pseudopotential-calculations-of-alsb-under-pressure
#3
H Algarni, O A Al-Hagan, N Bouarissa, M A Khan, T F Alhuwaymel
The dependence on hydrostatic pressure of the electronic and optical properties of zinc-blende AlSb semiconducting material in the pressure range of 0-20kbar has been reported using a pseudopotential approach. At zero pressure, our findings showed that the electron and heavy hole effective masses are 0.11 and 0.38m0, respectively. Moreover, our results yielded values of 3.3289 and 11.08 for refractive index and high frequency dielectric constant, respectively. These results are found to be in good accord with experiment...
September 14, 2017: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/28934659/comparison-on-the-effects-of-water-borne-and-dietary-borne-accumulated-zno-nanoparticles-on-daphnia-magna
#4
Yanjiao Chen, Fengxia Wu, Wenying Li, Tiangang Luan, Li Lin
Nanoparticles (NPs) can exert toxicity to aquatic animals through water and dietary exposure. However, little is known about the contribution of the two exposure pathways to the total toxicity of NPs to aquatic animals. In the present study, we fed Daphnia magna with ZnO NPs-accumulated-algae or directly exposed them to ZnO NPs suspension at the same Zn concentration. The body Zn concentrations were the same in both treatments, but the surface elastic modulus in the water-borne group was lower than that in the dietary-borne group, indicating more severe surface damage in the water-borne treatment...
August 25, 2017: Chemosphere
https://www.readbyqxmd.com/read/28934608/chemical-free-fabrication-of-n-p-dual-doped-honeycomb-like-carbon-as-an-efficient-electrocatalyst-for-oxygen-reduction
#5
Lianwen Zhu, Jun Wu, Qiao Zhang, Xiangkui Li, Yiming Li, Xuebo Cao
Heteroatom-doped nanoporous carbons are now emerging as alternatives to platinum and its alloys as electrocatalysts to facilitate oxygen reduction reaction in metal-air batteries and fuel cells. However, the synthesis of nanoporous carbons usually involve in complicated procedures and intensive chemicals, which may dramatically raise their manufacture cost that even surpasses that of precious platinum. Herein, we demonstrate the single-step, chemical-free fabrication of N, P dualdoped honeycomb carbon that has hierarchically porous structure and oxygen electrocatalysis activity close to the benchmark Pt/C...
August 23, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28934464/recruitment-and-delivery-of-the-fission-yeast-rst2-transcription-factor-via-a-local-genome-structure-counteracts-repression-by-tup1-family-corepressors
#6
Ryuta Asada, Miki Umeda, Akira Adachi, Satoshi Senmatsu, Takuya Abe, Hiroshi Iwasaki, Kunihiro Ohta, Charles S Hoffman, Kouji Hirota
Transcription factors (TFs) determine the transcription activity of target genes and play a central role in controlling the transcription in response to various environmental stresses. Three dimensional genome structures such as local loops play a fundamental role in the regulation of transcription, although the link between such structures and the regulation of TF binding to cis-regulatory elements remains to be elucidated. Here, we show that during transcriptional activation of the fission yeast fbp1 gene, binding of Rst2 (a critical C2H2 zinc-finger TF) is mediated by a local loop structure...
September 19, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/28934413/factors-extending-the-chronological-lifespan-of-yeast-ecl1-family-genes
#7
Hokuto Ohtsuka, Hirofumi Aiba
Ecl1 family genes are conserved among yeast, in which their overexpression extends chronological lifespan. Ecl1 family genes were first identified in the fission yeast Schizosaccharomyces pombe; at the time, they were considered noncoding RNA owing to their short coding sequence of fewer than 300 base pairs. Schizosaccharomyces pombe carries three Ecl1 family genes, ecl1+, ecl2+ and ecl3+, whereas Saccharomyces cerevisiae has one, ECL1. Their overexpression extends chronological lifespan, increases oxidative stress resistance and induces sexual development in fission yeast...
November 1, 2017: FEMS Yeast Research
https://www.readbyqxmd.com/read/28934354/synthesis-of-irregular-graphene-oxide-tubes-using-green-chemistry-and-their-potential-use-as-reinforcement-materials-for-biomedical-applications
#8
Ángel Serrano-Aroca, Sanjukta Deb
Micrometer length tubes of graphene oxide (GO) with irregular form were synthesised following facile and green metal complexation reactions. These materials were obtained by crosslinking of GO with calcium, zinc or strontium chlorides at three different temperatures (24, 34 and 55°C) using distilled water as solvent for the compounds and following a remarkably simple and low-cost synthetic method, which employs no hazardous substances and is conducted without consumption of thermal or sonic energy. These irregular continuous GO networks showed a very particular interconnected structure by Field Emission Scanning Electron Microscopy with Energy-Disperse X-Ray Spectroscopy for elemental analysis and High-resolution Transmission Electron Microscopy with Scanning Transmission Electron Microscope Dark Field Imaging, and were analysed by Raman Spectroscopy...
2017: PloS One
https://www.readbyqxmd.com/read/28934259/copper-and-zinc-content-in-wild-game-shot-with-lead-or-non-lead-ammunition-implications-for-consumer-health-protection
#9
Daniela Schlichting, Christine Sommerfeld, Christine Müller-Graf, Thomas Selhorst, Matthias Greiner, Antje Gerofke, Ellen Ulbig, Carl Gremse, Markus Spolders, Helmut Schafft, Monika Lahrssen-Wiederholt
The aim of this study was to examine the contamination of game meat with copper and zinc and establish whether the use of alternative (non-lead) ammunition can lead to higher or unsafe levels of copper and zinc in the meat of roe deer, wild boar and red deer. The research project "Safety of game meat obtained through hunting" (LEMISI) was conducted in Germany with the purpose of examining the entry of lead as well as copper and zinc into the meat of hunted game when using either lead or non-lead ammunition...
2017: PloS One
https://www.readbyqxmd.com/read/28934220/prediction-of-thermal-conductivity-of-polyvinylpyrrolidone-pvp-electrospun-nanocomposite-fibers-using-artificial-neural-network-and-prey-predator-algorithm
#10
Waseem S Khan, Nawaf N Hamadneh, Waqar A Khan
In this study, multilayer perception neural network (MLPNN) was employed to predict thermal conductivity of PVP electrospun nanocomposite fibers with multiwalled carbon nanotubes (MWCNTs) and Nickel Zinc ferrites [(Ni0.6Zn0.4) Fe2O4]. This is the second attempt on the application of MLPNN with prey predator algorithm for the prediction of thermal conductivity of PVP electrospun nanocomposite fibers. The prey predator algorithm was used to train the neural networks to find the best models. The best models have the minimal of sum squared error between the experimental testing data and the corresponding models results...
2017: PloS One
https://www.readbyqxmd.com/read/28934107/cultivar-and-metal-specific-effects-of-endophytic-bacteria-in-helianthus-tuberosus-exposed-to-cd-and-zn
#11
Blanca Montalbán, Sofie Thijs, Mª Carmen Lobo, Nele Weyens, Marcel Ameloot, Jaco Vangronsveld, Araceli Pérez-Sanz
Plant growth promoting endophytic bacteria (PGPB) isolated from Brassica napus were inoculated in two cultivars of Helianthus tuberosus (VR and D19) growing on sand supplemented with 0.1 mM Cd or 1 mM Zn. Plant growth, concentrations of metals and thiobarbituric acid (TBA) reactive compounds were determined. Colonization of roots of H. tuberosus D19 by Pseudomonas sp. 262 was evaluated using confocal laser scanning microscopy. Pseudomonas sp. 228, Serratia sp. 246 and Pseudomonas sp. 262 significantly enhanced growth of H...
September 21, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28933852/entangled-two-photon-absorption-cross-section-on-the-808-nm-region-for-the-common-dyes-zinc-tetraphenylporphyrin-and-rhodamine-b
#12
Juan Pablo Villabona-Monsalve, Omar Calderón-Losada, Mayerlin Nunez Portela, Alejandra Valencia
We report the measurement of the entangled two photon absorption (ETPA) cross section, σΕ , at 808 nm on organic chromophores in solution in a low photon flux regime. We performed measurements on Zinc tetraphenylporphyrin (ZnTPP) in Toluene and Rhodamine B (RhB) in Methanol. This is, to the best of our knowledge, the first time that σΕ is measured for RhB. Additionally, we report a study of the dependence of σΕ on the molecular concentration for both molecular systems. In contrast to previous experiments, our measurements are based on detecting the pairs of photons that are transmitted by the molecular system...
September 21, 2017: Journal of Physical Chemistry. A
https://www.readbyqxmd.com/read/28933844/mind-the-metal-a-fragment-library-derived-zinc-impurity-binds-the-e2-ubiquitin-conjugating-enzyme-ube2t-and-induces-structural-rearrangements
#13
Francesca E Morreale, Andrea Testa, Viduth K Chaugule, Alessio Bortoluzzi, Alessio Ciulli, Helen Walden
Efforts to develop inhibitors, activators and effectors of biological reactions using small molecule libraries are often hampered by interference compounds, artifacts and false positives that permeate the pool of initial hits. Here we report the discovery of a promising initial hit compound targeting the Fanconi anemia ubiquitin-conjugating enzyme Ube2T and describe its biophysical and biochemical characterization. Analysis of the co-crystal structure led to the identification of a contaminating zinc ion as solely responsible for the observed effects...
September 21, 2017: Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/28933831/one-dimensional-zinc-based-coordination-polymer-as-a-higher-capacity-anode-material-for-lithium-ion-batteries
#14
Yidan Song, Lili Yu, Yuanrui Gao, Changdong Shi, Meiling Cheng, Xianmei Wang, Hong-Jiang Liu, Qi Liu
A zinc-based one-dimensional (1D) coordination polymer ([Zn(H2mpca)2(tfbdc)(H2O)], Zn-ODCP) has been synthesized and characterized by spectroscopic and physicochemical methods, single-crystal X-ray diffraction, and thermogravimetric analysis (H2mpca = 3-methyl-1H-pyrazole-4-carboxylic acid; H2tfbdc = 2,3,5,6-tetrafluoroterephthalic acid). Zn-ODCP shows blue luminescence in the solid state. When Zn-ODCP acts as an anode material for lithium ion batteries, it exhibits a good cyclic stability and a higher reversible capacity of 300 mAh g(-1) at 50 mA g(-1) after 50 cycles...
September 21, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28933531/room-temperature-activation-of-ingazno-thin-film-transistors-via-he-irradiation
#15
Michael G Stanford, Joo Hyon Noh, Kyle Mahady, Anton V Ievlev, Petro Maksymovych, Olga S Ovchinnikova, Philip D Rack
Amorphous indium gallium zinc oxide (a-IGZO) is a transparent semiconductor which has demonstrated excellent electrical performance as thin film transistors (TFTs). However, a high-temperature activation process is generally required which is incompatible for next-generation flexible electronic applications. In this work, He(+) irradiation is demonstrated as an athermal activation process for a-IGZO TFTs. Controlling He+ dose enables the tuning of charge density and a dose of 1×10(14) He(+)/cm(2) induces a change in charge density of 2...
September 21, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28933279/zinc-transporter-protein-tzn-1-may-also-play-a-role-in-conidiation-pathway-of-neurospora-crassa-an-insight-using-proteogenomic-approachusing-proteogenomic-approach
#16
Divya Rupa Venkata Pandala, Jogeswar Gadi, Kiranmayi Patnala
Zinc transporter (tzn-1) of Neurospora crassa plays a crucial role in conidiation pathway, as its removal results in aconidiation which was reported in our earlier studies. Present study depicts the role of tzn-1 in conidiation process, by comparing knockout (KO) mutants zinc transporter KO (Δtzn-1) and aconidiating gene KO (Δacon-3) with wild oak ridge (OR) 74 'A' strain by 'Proteo-genomic' approach. Firstly, nine commonly overexpressed protein spots from the two sets (Δtzn-1 to wild and Δacon-3 to wild) were analyzed by combining 2-Dimensional gel electrophoresis (2DE) with Matrix Associated Laser Desorption/Ionization mass spectrometry -Peptide Mass Fingerprint (MALDI-PMF)...
September 19, 2017: Protein and Peptide Letters
https://www.readbyqxmd.com/read/28933278/an-insight-into-biophysical-characterization-and-genotoxicity-assessment-of-concanavalin-a-immobilized-on-zinc-oxide-nanoparticles
#17
Aabgeena Naeem, Taqi Khan, Tauqir Alam, Qayyum Husain
Concanavalin A (Con A) immobilized on the hexagonal zinc oxide (ZnO) nanoparticles, using various techniques like atomic force microscopy, scanning electron microscopy and X-ray diffraction showed changes in morphology of Con A and ZnO nanoparticles. FT-IR spectroscopy confirmed the linking of Con A amino groups with ZnO nanoparticles. Con A immobilized nanoparticles in contrast to native lectin showed visible changes in hemagglutination activity as confirmed by pH dependence studies using fluorimetry. The Con A coated ZnO nanoparticles did not induce any significant damage to whole cell DNA as revealed from comet assay or plasmid DNA...
September 19, 2017: Protein and Peptide Letters
https://www.readbyqxmd.com/read/28933241/characterization-of-human-s-adenosyl-homocysteine-hydrolase-in-vitro-and-identification-of-its-potential-inhibitors
#18
Weiwei Hao, Yanhua Li, Qiuli Shan, Tian Han, Wencheng Li, Sheng He, Kongkai Zhu, Yumei Li, Xiaojun Tan, Jinsong Gu
Human S-adenosyl-homocysteine hydrolase (SAHH, E.C.3.3.1.1) has been considered to be an attractive target for the design of medicines to treat human disease, because of its important role in regulating biological methylation reactions to catalyse the reversible hydrolysis of S-adenosylhomocysteine (SAH) to adenosine (Ado) and l-homocysteine (Hcy). In this study, SAHH protein was successfully cloned and purified with optimized, Pichia pastoris (P. pastoris) expression system. The biological activity results revealed that, among the tested compounds screened by ChemMapper and SciFinder Scholar, 4-(3-hydroxyprop-1-en-1-yl)-2-methoxyphenol (coniferyl alcohol, CAS: 458-35-5, ZINC: 12359045) exhibited the highest inhibition against rSAHH (IC50= 34 nM)...
December 2017: Journal of Enzyme Inhibition and Medicinal Chemistry
https://www.readbyqxmd.com/read/28933019/effects-of-municipal-solid-waste-and-sewage-sludge-compost-based-growing-media-on-the-yield-and-heavy-metal-content-of-four-lettuce-cultivars
#19
Concetta Eliana Gattullo, Carlo Mininni, Angelo Parente, Francesco Fabiano Montesano, Ignazio Allegretta, Roberto Terzano
Compost has been recently suggested as an alternative to peat for the preparation of growing substrates in soilless cultivation systems. However, some physico-chemical properties of compost may reduce plant performance and endanger the quality of productions, in particular for possible heavy metal accumulation in edible parts. This study aims at evaluating the suitability of a municipal solid waste compost (MSWC) and a sewage sludge compost (SSC) as components of growing media for the soilless cultivation of lettuce (Lactuca sativa L...
September 20, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28932981/the-spatial-distribution-and-accumulation-characteristics-of-heavy-metals-in-steppe-soils-around-three-mining-areas-in-xilinhot-in-inner-mongolia-china
#20
Yongfei Gao, Honglin Liu, Guixiang Liu
Metal deposition has become a major environmental problem in China due to its adverse effects on human and ecosystem health, particularly in Inner Mongolia, where frequent dust storms (due to steppe degradation and desertification) and soil pollution (associated with the increasing mining activities) have occurred in recent decades. To assess spatial distribution of heavy metals and the influences of mining activities on geochemical behavior of heavy metals in soils, soil samples with depth of 0-10, 10-20, and 20-30 cm at each site were collected from different directions in the vicinity of three mines (coal mine, gold mine, and fluorite mine) in a typical steppe zone of Inner Mongolia, China...
September 20, 2017: Environmental Science and Pollution Research International
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