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colorectal anastomotic leakage

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https://www.readbyqxmd.com/read/29322627/safety-and-feasibility-of-laparoscopic-reoperation-for-treatment-of-anastomotic-leakage-after-laparoscopic-colorectal-cancer-surgery
#1
Masakatsu Numata, Tomohiro Yamaguchi, Yusuke Kinugasa, Akio Shiomi, Hiroyasu Kagawa, Yushi Yamakawa, Akinobu Furuatni, Shoichi Manabe, Yusuke Yamaoka, Kakeru Torii, Shunichiro Kato
INTRODUCTION: The safety and feasibility of laparoscopic reoperation for anastomotic leakage remain unclear. METHODS: A total of 3321 patients underwent laparoscopic surgery for primary colorectal cancer at a tertiary referral center from September 2002 to May 2016. Of these, 31 patients who underwent reoperation for treatment of anastomotic leakage were enrolled in this study and divided into two reoperation groups: laparoscopic (n = 15) and open (n = 16)...
January 11, 2018: Asian Journal of Endoscopic Surgery
https://www.readbyqxmd.com/read/29316159/safety-of-extraperitoneal-rectal-resection-and-ileo-or-colorectal-anastomosis-without-loop-ileostomy-in-patients-with-peritoneal-metastases-treated-with-crs-and-hipec
#2
Andreas Brandl, Wieland Raue, Felix Aigner, Maria Clara Arroyave, Johann Pratschke, Beate Rau
AIM: Extraperitoneal rectal resection combined with complete peritonectomy of the pelvis in patients with peritoneal metastases is associated with a high rate of morbidity and mortality due to anastomotic leakage (AL). Therefore, many centers tend to perform loop ileostomy to reduce the clinical impact of AL. The aim of this study was to analyze the need for protective stoma creation in this patient group to avoid major complications and mortality in the case of AL. METHOD: We analyzed 53 patients who underwent extraperitoneal rectal resection from 409 consecutive patients treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC) at our department between January 1997 and December 2016...
January 6, 2018: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/29316129/anastomotic-leakage-after-side-to-end-anastomosis-for-rectal-cancer-does-leakage-location-matter
#3
Elisabeth Hain, Léon Maggiori, Magaly Zappa, Justine Prost À la Denise, Yves Panis
AIM: To assess outcome according to location of anastomotic leakage (AL) after side-to-end stapler or manual low colorectal or coloanal anastomosis following laparoscopic total mesorectal excision (TME) for rectal cancer. METHODS: All patients presenting with symptomatic or asymptomatic AL after TME and side-to-end low anastomosis for rectal cancer performed from 2005 to 2014 were identified from our prospective database. CT-scans with contrast enema were reviewed to assess location of AL origin...
January 6, 2018: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/29315418/fertility-outcomes-in-women-experiencing-severe-complications-after-surgery-for-colorectal-endometriosis
#4
C Ferrier, H Roman, Y Alzahrani, E Mathieu d'Argent, S Bendifallah, N Marty, M Perez, C Rubod, P Collinet, E Daraï, M Ballester
STUDY QUESTION: What are the fertility outcomes in women wishing to conceive after experiencing a severe complication from surgical removal of colorectal endometriosis? SUMMARY ANSWER: The pregnancy rate (PR) among women who wished to conceive after a severe complication of surgery for colorectal endometriosis was 41.2% (spontaneously for 80%, after ART procedure for 20%). WHAT IS KNOWN ALREADY: While the long-term benefit of surgery on pain and quality of life is well documented for women with colorectal endometriosis, it exposes women to the risk of severe complications...
January 5, 2018: Human Reproduction
https://www.readbyqxmd.com/read/29306581/pringle-maneuver-increases-the-risk-of-anastomotic-leakage-after-colonic-resection-in-rats
#5
Boris Jansen-Winkeln, Evangelos Tagkalos, Axel Heimann, Timo Gaiser, Daniela Hirsch, Ines Gockel, Jens Mittler, Hauke Lang, Stefan Heinrich
BACKGROUND: Many centers use the Pringle's maneuver during liver resections. Since this maneuver might impair healing of bowel anastomoses, we evaluated its influence on the healing of colonic anastomosis in rats. METHODS: Male Wistar rats underwent median laparotomy and sigmoid resection with end-to-end anastomosis under inhalation anesthesia. Thereafter, rats received a 25 minutes Pringle's maneuver (PM, group 1) or were kept under anesthesia for the same period of time (group 2)...
January 3, 2018: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/29303807/mucus-microbiome-of-anastomotic-tissue-during-surgery-has-predictive-value-for-colorectal-anastomotic-leakage
#6
Jasper B van Praagh, Marcus C de Goffau, Ilsalien S Bakker, Harry van Goor, Hermie J M Harmsen, Peter Olinga, Klaas Havenga
OBJECTIVE: The aim of the present study is to investigate the association of gut microbiota, depending on treatment method, with the development of colorectal anastomotic leakage (AL). BACKGROUND: AL is a major cause for morbidity and mortality after colorectal surgery, but the mechanism behind this complication still is not fully understood. METHODS: Bacterial DNA was isolated from 123 "donuts" of patients where a stapled colorectal anastomosis was made and was analyzed using 16S MiSeq sequencing...
January 4, 2018: Annals of Surgery
https://www.readbyqxmd.com/read/29282510/changes-in-clinical-practice-reduce-the-rate-of-anastomotic-leakage-after-colorectal-resections
#7
Henrik Iversen, Madelene Ahlberg, Marja Lindqvist, Christian Buchli
BACKGROUND: Anastomotic leakage is a serious clinical problem after colorectal resections and is associated with a significantly increased length of stay, morbidity and mortality. The aim of the present study was to evaluate the effect of changes in clinical practice on anastomotic leakage rate after colorectal resections. METHODS: Retrospective cohort study based on prospectively collected data. All 894 patients with primary anastomosis after colorectal resection at a tertiary referral center between 2006 and 2013 were analyzed...
December 28, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/29277820/the-severity-of-anastomotic-leakage-may-negatively-impact-the-long-term-prognosis-of-colorectal-cancer
#8
Hidekazu Takahashi, Naotsugu Haraguchi, Junichi Nishimura, Taishi Hata, Hirofumi Yamamoto, Chu Matsuda, Tsunekazu Mizushima, Yuichiro Doki, Masaki Mori
BACKGROUND: Anastomotic leakage is a major critical complication in colorectal resection. Although its relevance to oncological outcome has been widely investigated, the correlation between the severity of anastomotic leakage and oncological outcome is not well understood. PATIENTS AND METHODS: The clinical characteristics of 615 patients who underwent curative resection of colorectal cancer with anastomosis and normal healing were compared with 44 similar patients who experienced anastomotic leakage...
January 2018: Anticancer Research
https://www.readbyqxmd.com/read/29273883/calcification-of-the-iliac-arteries-a-marker-for-leakage-risk-in-rectal-anastomosis-a-blinded-clinical-trial
#9
Julius Pochhammer, Fridolin Tröster, Gunnar Blumenstock, Julienne Closset, Stefanie Lang, Marie-Pascale Weller, Michael Schäffer
PURPOSE: Anastomotic leakage (AL) is associated with increased morbidity and mortality after colorectal surgery. Calcification of the arteries has been identified as a risk factor for cardiovascular events and can be reliably measured on computed tomography using software assistance. The aim of this prospective study was to prove the value of calcium scoring of the iliac arteries as a predictor of AL after rectal anastomosis. METHODS: Consecutive patients who underwent colorectal resection with rectal anastomosis were analyzed...
December 22, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/29230591/intraoperative-use-of-icg-fluorescence-imaging-to-reduce-the-risk-of-anastomotic-leakage-in-colorectal-surgery-a-systematic-review-and-meta-analysis
#10
REVIEW
R Blanco-Colino, E Espin-Basany
BACKGROUND: Indocyanine green (ICG) fluorescence imaging has been proven to be an effective tool to assess anastomotic perfusion. The aim of this systematic review and meta-analysis was to evaluate its efficacy in reducing the anastomotic leakage (AL) rate after colorectal surgery. METHODS: PubMed, Scopus, WOS, Google Scholar and Cochrane Library were searched up to January 2017 for studies comparing fluorescence imaging with standard care. ClinicalTrials.gov register was searched for ongoing trials...
December 11, 2017: Techniques in Coloproctology
https://www.readbyqxmd.com/read/29202966/choosing-the-right-surgical-technique-for-deep-endometriosis-shaving-disc-excision-or-bowel-resection
#11
REVIEW
Olivier Donnez, Horace Roman
Deep endometriosis (DE) remains the most difficult endometriotic entity to treat. Medical treatment for DE can reduce symptoms but does not cure the disease, and surgical removal of the lesion is required when lesions are symptomatic, impairing bowel, urinary, sexual, and reproductive functions. Although several surgical techniques such as laparoscopic bowel resection, disc excision, and rectal shaving have been described, there is no consensus regarding the choice of technique or the timing of surgery. Our review of publications reporting results and complications of surgery for rectovaginal DE reveals a relatively higher complication rate after bowel resection compared with shaving and disc excision, especially for rectovaginal fistulas, anastomotic leakage, delayed hemorrhage, and long-term bladder catheterization...
December 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/29198926/does-the-application-of-ankaferd-blood-stopper-rectally-have-positive-effects-on-the-healing-of-colorectal-anastomosis-and-prevention-of-anastomotic-leakage-an-experimental-study
#12
Serdar Kuru, Kemal Kismet, Yusuf Murat Bag, Aziz Mutlu Barlas, Mehmet Senes, Murat Durak, Nihat Yumusak, Mustafa Kemal Urhan, Turgut Cavusoglu, Recep Pekcici
The purpose of this experimental study was to evaluate the potential effects on the healing of colorectal anastomoses of the rectal administration of Ankaferd Blood Stopper (ABS). Thirty Wistar-Albino male rats were randomly separated into 3 groups. In the sham group, only laparotomy and colonic mobilization was performed. In the other 2 groups, colon transection and anastomosis were carried out. Saline (2 mL, 0.9% NaCl) was given rectally via a feeding tube for 10 days after the surgical procedure in the sham and control groups...
November 29, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29164809/nonsteroidal-anti-inflammatory-drugs-and-anastomotic-dehiscence-after-colorectal-surgery-a-meta-analysis
#13
REVIEW
Yeqian Huang, Stephen R Tang, Christopher J Young
BACKGROUND: Enhanced recovery after surgery protocols supports the post-operative use of nonsteroidal anti-inflammatory drugs (NSAIDs) to minimize the use of opioids. However, there is an increasing concern on the impaired wound healing of anastomosis associated with NSAID use, potentially causing a higher risk of anastomotic leakage. The aim was to conduct a meta-analysis to evaluate the association of NSAIDs with anastomotic leakage after colorectal surgery. METHODS: A literature search was conducted using the MEDLINE, PubMed, Cochrane Library and Clinicaltrial...
November 22, 2017: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/29164476/diverticular-colitis-with-progression-to-ulcerative-colitis-after-sigmoidectomy
#14
Atsuyo Ikeda, Tsunekazu Mizushima, Yutaro Egashira, Hidekazu Takahashi, Norikatsu Miyoshi, Naotsugu Haraguchi, Taishi Hata, Chu Matsuda, Yuichiro Doki, Masaki Mori
Diverticular colitis is chronic inflammation of the colon where diverticula are present. The endoscopic and histopathological findings of this disease are sometimes similar to those of ulcerative colitis, and several reports describe cases of diverticular colitis that progressed to typical ulcerative colitis. A 77-year-old woman with intramesenteric penetration of the sigmoid diverticulum underwent low anterior resection. One month later, the patient experienced anastomotic leakage, and transverse colostomy was performed...
November 21, 2017: Clinical Journal of Gastroenterology
https://www.readbyqxmd.com/read/29159744/treatment-and-outcome-of-synchronous-colorectal-carcinomas-a-nationwide-study
#15
A C R K Bos, R A Matthijsen, F N van Erning, M G H van Oijen, H J T Rutten, V E P P Lemmens
BACKGROUND: Synchronous colorectal carcinomas (CRC) occur in 1-8% of patients diagnosed with CRC. This study evaluated treatment patterns and patient outcomes in synchronous CRCs compared with solitary CRC patients. METHODS: All patients diagnosed with primary CRC between 2008 and 2013, who underwent elective surgery, were selected from the Netherlands Cancer Registry. Using multivariable regressions, the effects of synchronous CRC were assessed for both short-term outcomes (prolonged postoperative hospital admission, anastomotic leakage, postoperative 30-day mortality, administration of neoadjuvant or adjuvant treatment), and 5-year relative survival (RS)...
November 20, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/29158731/routine-drainage-of-colorectal-anastomoses-an-evidence-based-review-of-the-current-literature
#16
REVIEW
Sameh Hany Emile, Tito M Abd El-Hamed
Background: The use of prophylactic drainage after colorectal anastomoses has been long debated. This report aimed to review the current literature discussing routine drainage of colorectal anastomoses highlighting two opposite perspectives (prodrainage and antidrainage) to demonstrate the clinical utility of prophylactic drainage and its proper indications. Methods: An organized literature search was conducted querying electronic databases and Google Scholar. Articles evaluating the role of routine prophylactic drainage after colorectal anastomosis were included and divided into two categories: articles supporting the use of drains (prodrainage) and articles disputing routine drainage (antidrainage)...
2017: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/29149427/the-impact-of-the-national-bowel-screening-program-in-the-netherlands-on-detection-and-treatment-of-endoscopically-unresectable-benign-polyps
#17
C C M Marres, C J Buskens, E Schriever, P C M Verbeek, M W Mundt, W A Bemelman, A W H van de Ven
BACKGROUND: In January 2014, a national bowel cancer screening program started in the Netherlands. The program is being implemented in phases until 2019. Due to this program, an increase in patients referred for a colorectal resection for benign, but endoscopically unresectable polyps, is expected. So far, most resections are performed according to oncological principles despite no pre-operative histological diagnosis of malignancy. The aim of this study was to analyze the increase in referred patients during the first year of the screening program and to compare pathological results and clinical outcome of resections of patients undergoing resection for benign polyps before and after implementation of screening...
November 2017: Techniques in Coloproctology
https://www.readbyqxmd.com/read/29147895/routine-virtual-ileostomy-following-restorative-proctocolectomy-for-familial-adenomatous-polyposis
#18
Peter C Ambe, Hubert Zirngibl, Gabriela Möslein
BACKGROUND: Anastomotic leakage (AL) is the most feared complication in colorectal surgery. A diverting ileostomy is routinely used to prevent or reduce morbidity and mortality following AL. However, a diverting ileostomy cannot prevent AL. Besides, diverting ileostomy might be associated with relevant complications. Herein, we introduce the virtual ileostomy as an alternative to diverting ileostomy in patients undergoing restorative proctocolectomy with ileal pouch-anal anastomosis (IPAA) for familial adenomatous polyposis (FAP)...
November 16, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/29134504/ketorolac-and-other-nsaids-increase-the-risk-of-anastomotic-leakage-after-surgery-for-gej-cancers-a-cohort-study-of-557-patients
#19
Kaare Terp Fjederholt, Cecilie Okholm, Lars Bo Svendsen, Michael Patrick Achiam, Jakob Kirkegård, Frank Viborg Mortensen
OBJECTIVE: The objective of this study is to investigate the impact of ketorolac and other nonsteroidal anti-inflammatory drugs on anastomotic leakage after surgery for gastro-esophageal-junction cancer. Within the last two decades, the incidence of gastro-esophageal-junction cancer has increased in the western world and surgery is the curative treatment modality of choice. Anastomotic leakage is a feared complication of gastro-esophageal surgery, as it increases recurrence, morbidity, and mortality...
November 13, 2017: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/29130231/-effect-of-postoperative-hyperglycemia-on-clinical-outcome-of-gastrointestinal-fistula-patients-undergoing-gastrointestinal-reconstruction
#20
Qiongyuan Hu, Jian'an Ren, Wenhao Tang, Jieshou Li
OBJECTIVE: To investigate the effect of hyperglycemia within postoperative 48 hours on gastrointestinal (GI) fistula patients without preoperative diagnosis of diabetes undergoing selective GI reconstruction. METHODS: Clinical data of GI fistula patients with age of 18 to 70 years and without diffuse peritonitis and systemic infection undergoing definitive GI reconstruction at Intestinal Fistula Center of Jinling Hospital from September 2012 to December 2015 were retrospectively analyzed...
October 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
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