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colorectal anastomotic leakage

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https://www.readbyqxmd.com/read/29149427/the-impact-of-the-national-bowel-screening-program-in-the-netherlands-on-detection-and-treatment-of-endoscopically-unresectable-benign-polyps
#1
C C M Marres, C J Buskens, E Schriever, P C M Verbeek, M W Mundt, W A Bemelman, A W H van de Ven
BACKGROUND: In January 2014, a national bowel cancer screening program started in the Netherlands. The program is being implemented in phases until 2019. Due to this program, an increase in patients referred for a colorectal resection for benign, but endoscopically unresectable polyps, is expected. So far, most resections are performed according to oncological principles despite no pre-operative histological diagnosis of malignancy. The aim of this study was to analyze the increase in referred patients during the first year of the screening program and to compare pathological results and clinical outcome of resections of patients undergoing resection for benign polyps before and after implementation of screening...
November 17, 2017: Techniques in Coloproctology
https://www.readbyqxmd.com/read/29147895/routine-virtual-ileostomy-following-restorative-proctocolectomy-for-familial-adenomatous-polyposis
#2
Peter C Ambe, Hubert Zirngibl, Gabriela Möslein
BACKGROUND: Anastomotic leakage (AL) is the most feared complication in colorectal surgery. A diverting ileostomy is routinely used to prevent or reduce morbidity and mortality following AL. However, a diverting ileostomy cannot prevent AL. Besides, diverting ileostomy might be associated with relevant complications. Herein, we introduce the virtual ileostomy as an alternative to diverting ileostomy in patients undergoing restorative proctocolectomy with ileal pouch-anal anastomosis (IPAA) for familial adenomatous polyposis (FAP)...
November 16, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/29134504/ketorolac-and-other-nsaids-increase-the-risk-of-anastomotic-leakage-after-surgery-for-gej-cancers-a-cohort-study-of-557-patients
#3
Kaare Terp Fjederholt, Cecilie Okholm, Lars Bo Svendsen, Michael Patrick Achiam, Jakob Kirkegård, Frank Viborg Mortensen
OBJECTIVE: The objective of this study is to investigate the impact of ketorolac and other nonsteroidal anti-inflammatory drugs on anastomotic leakage after surgery for gastro-esophageal-junction cancer. Within the last two decades, the incidence of gastro-esophageal-junction cancer has increased in the western world and surgery is the curative treatment modality of choice. Anastomotic leakage is a feared complication of gastro-esophageal surgery, as it increases recurrence, morbidity, and mortality...
November 13, 2017: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/29130231/-effect-of-postoperative-hyperglycemia-on-clinical-outcome-of-gastrointestinal-fistula-patients-undergoing-gastrointestinal-reconstruction
#4
Qiongyuan Hu, Jian'an Ren, Wenhao Tang, Jieshou Li
OBJECTIVE: To investigate the effect of hyperglycemia within postoperative 48 hours on gastrointestinal (GI) fistula patients without preoperative diagnosis of diabetes undergoing selective GI reconstruction. METHODS: Clinical data of GI fistula patients with age of 18 to 70 years and without diffuse peritonitis and systemic infection undergoing definitive GI reconstruction at Intestinal Fistula Center of Jinling Hospital from September 2012 to December 2015 were retrospectively analyzed...
October 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/29118559/long-term-efficacy-of-vacuum-assisted-therapy-endo-sponge-%C3%A2-in-large-anastomotic-leakages-following-anterior-rectal-resection
#5
Alessandro Mussetto, Rosario Arena, Andrea Buzzi, Lorenzo Fuccio, Silvia Dari, Mario Luciano Brancaccio, Omero Triossi
Background: The aim of our study was to test the long-term efficacy of Endo-SPONGE(®) therapy in a group of patients treated in our center with vacuum-assisted therapy because of anastomotic leakages after colorectal surgery. Methods: Eleven patients [male: 6; mean age: 71 (range: 44-82) years] who had anastomotic leakage treated with Endo-SPONGE(®) placement were included in the study. Patient records were examined retrospectively. All patients with documented anastomotic leakage on abdominal computed tomography following an anterior resection of the rectum for rectal cancer underwent sigmoidoscopy to determine the extent of the anastomotic defect and the size of the presacral abscess...
2017: Annals of Gastroenterology: Quarterly Publication of the Hellenic Society of Gastroenterology
https://www.readbyqxmd.com/read/29112566/what-is-the-risk-of-anastomotic-leak-after-repeat-intestinal-resection-in-patients-with-crohn-s-disease
#6
W Forrest Johnston, Caitlin Stafford, Todd D Francone, Thomas E Read, Peter W Marcello, Patricia L Roberts, Rocco Ricciardi
BACKGROUND: Approximately half of Crohn's patients require intestinal resection, and many need repeat resections. OBJECTIVE: The purpose of this study was to evaluate the increased risk of clinical anastomotic leak in patients with a history of previous intestinal resection undergoing repeat resection with anastomosis for Crohn's disease. DESIGN: This was a retrospective analysis of prospectively collected departmental data with 100% capture...
December 2017: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/29080956/validation-of-an-online-risk-calculator-for-the-prediction-of-anastomotic-leak-after-colon-cancer-surgery-and-preliminary-exploration-of-artificial-intelligence-based-analytics
#7
T Sammour, L Cohen, A I Karunatillake, M Lewis, M J Lawrence, A Hunter, J W Moore, M L Thomas
BACKGROUND: Recently published data support the use of a web-based risk calculator ( www.anastomoticleak.com ) for the prediction of anastomotic leak after colectomy. The aim of this study was to externally validate this calculator on a larger dataset. METHODS: Consecutive adult patients undergoing elective or emergency colectomy for colon cancer at a single institution over a 9-year period were identified using the Binational Colorectal Cancer Audit database. Patients with a rectosigmoid cancer, an R2 resection, or a diverting ostomy were excluded...
October 28, 2017: Techniques in Coloproctology
https://www.readbyqxmd.com/read/29067577/impact-of-hospital-and-surgeon-case-volume-on-morbidity-in-colorectal-endometriosis-management-a-plea-to-define-criteria-for-expert-centers
#8
Sofiane Bendifallah, Horace Roman, Chrystel Rubod, Pierre Leguevaque, Antoine Watrelot, Nicolas Bourdel, Marcos Ballester, Emile Darai
National and international guidelines recommend referring patients with severe forms of endometriosis to expert centers. However, there is a lack of clear criteria to define an expert center. We examined the roles of surgeon and hospital procedure volumes as determinants of morbidity in deep infiltrating endometriosis of the rectum and sigmoid colon (DIERS). METHODS: We conducted a French retrospective multicenter study of hospital facilities performing colorectal surgery for DIERS in 2015...
October 24, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/29065778/upregulation-of-vegfr1-in-a-rat-model-of-esophagogastric-anastomotic-healing
#9
Laura Christina Landes, Daniel Drescher, Evangelos Tagkalos, Peter P Grimminger, René Thieme, Boris Jansen-Winkeln, Hauke Lang, Ines Gockel
INTRODUCTION: Anastomotic leakage after gastrointestinal surgery is a significant cause of morbidity and mortality. Esophagogastric and colorectal anastomoses are vulnerable to leakage. Extended knowledge of growth factors and their receptors is needed to understand anatomic healing. METHODS: The expression pattern of vascular growth factor receptor (VEGFR1-3), epidermal growth factor receptor (EGFR), platelet-derived growth factor receptor (PDGFRα/β) and keratinocyte growth factor receptor (KGFR) were analyzed by semiquantitative-PCR in the rat intestinal tract and in esophagogastric anastomosis 5d after surgery...
October 25, 2017: Acta Chirurgica Belgica
https://www.readbyqxmd.com/read/29061337/c-reactive-protein-as-a-predictor-of-anastomotic-leakage-in-colorectal-surgery-comparison-between-open-and-laparoscopic-surgery
#10
María Ramos Fernández, Francisco Rivas Ruiz, Alberto Fernández López, Carmelo Loinaz Segurola, José María Fernández Cebrián, Fernando de la Portilla de Juan
INTRODUCTION: Anastomotic leak (AL) is a serious complication in colorectal surgery due to its increase in morbidity and mortality. The aim of this prospective non-randomised study is to determine whether C-reactive Protein (CRP) is useful as a predictor of AL in patients undergoing open versus laparoscopic surgery. METHODS: A total of 168 patients undergoing elective colorectal surgery were included. CRP was measured daily during the first 5postoperative days. Complications, specially AL, were analysed...
October 20, 2017: Cirugía Española
https://www.readbyqxmd.com/read/29059489/risk-factors-for-anastomotic-leakage-following-ileosigmoid-or-ileorectal-anastomosis
#11
J Segelman, I Matsson, B Jung, P J Nilsson, G Palmer, C Buchli
AIM: Reconstruction with an ileosigmoidal anastomosis (ISA) or ileorectal anastomosis (IRA) is a surgical option after a subtotal colectomy. Anastomotic leakage (AL) is a significant risk and high rates have been reported (AL) but here is however limited understanding of the risk factors involved. The aim of this study was to assess the established and potential predictors of AL following ISA and IRA. METHOD: This is a retrospective cohort-study including all patients who have undergone ISA or IRA at three Swedish referral centres for colorectal surgery between January 2007 and March 2015...
October 23, 2017: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/29049000/oral-nutrition-as-a-form-of-pre-operative-enhancement-in-patients-undergoing-surgery-for-colorectal-cancer-a-systematic-review
#12
Emma R J Bruns, Tanja E Argillander, Baukje Van Den Heuvel, Christianne J Buskens, Peter Van Duijvendijk, Renate M Winkels, Annette Kalf, Edwin S Van Der Zaag, Eelco B Wassenaar, Willem A Bemelman, Barbara C Van Munster
BACKGROUND: Nutritional status has major impacts on the outcome of surgery, in particular in patients with cancer. The aim of this review was to assess the merit of oral pre-operative nutritional support as a part of prehabilitation in patients undergoing surgery for colorectal cancer. METHODS: A systematic literature search and meta-analysis was performed according to the Preferred Reporting of Systematic Reviews and Meta-Analyses (PRISMA) recommendations in order to review all trials investigating the effect of oral pre-operative nutritional support in patients undergoing colorectal surgery...
October 19, 2017: Surgical Infections
https://www.readbyqxmd.com/read/29024743/stenting-as-a-bridge-to-resection-versus-emergency-surgery-for-left-sided-colorectal-cancer-with-malignant-obstruction-a-systematic-review-and-meta-analysis
#13
REVIEW
Xin Wang, Jianjun He, Xuan Chen, Qingqiang Yang
PURPOSE: This study aims to discuss the safety and feasibility of a combined treatment consisting of stent insertion and elective surgery for left-sided colorectal cancer with malignant obstruction. METHODS: Randomized clinical trials (RCTs) that discussed the safety and feasibility of stenting as a bridge to surgery in malignant colorectal cancer were identified in a search of medical databases, including PubMed, Embase, Cochrane Library, and SCIENCE. Each paper's quality was assessed using the Jadad scale...
October 10, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/29024481/late-leakage-after-anterior-resection-a-defunctioning-stoma-alters-the-clinical-course-of-anastomotic-leakage
#14
H Jutesten, J Draus, J Frey, G Neovius, G Lindmark, P Buchwald, M L Lydrup
AIM: Anastomotic leakage (AL) is common after anterior resection (AR). Long term clinical outcomes of AL including late presenting leakages (LL) are not well studied. This study was undertaken to assess clinical features of LL with respect to incidence, association to predisposing factors, and need for reintervention. METHODS: The Swedish Colorectal Cancer Registry (SCRCR) was explored for AL cases after AR for rectal cancer in patients operated in the south of Sweden from 01-01(_) 2001 to 31-12-2011...
October 12, 2017: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/28970733/definition-of-colorectal-anastomotic-leakage-a-consensus-survey-among-dutch-and-chinese-colorectal-surgeons
#15
Stefanus J van Rooijen, Audrey Chm Jongen, Zhou-Qiao Wu, Jia-Fu Ji, Gerrit D Slooter, Rudi Mh Roumen, Nicole D Bouvy
AIM: To determine the level of consensus on the definition of colorectal anastomotic leakage (CAL) among Dutch and Chinese colorectal surgeons. METHODS: Dutch and Chinese colorectal surgeons were asked to partake in an online questionnaire. Consensus in the online questionnaire was defined as > 80% agreement between respondents on various statements regarding a general definition of CAL, and regarding clinical and radiological diagnosis of the complication. RESULTS: Fifty-nine Dutch and 202 Chinese dedicated colorectal surgeons participated in the online survey...
September 7, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28934741/successful-management-of-a-positive-air-leak-test-during-laparoscopic-colorectal-surgery
#16
Kazuhito Sasaki, Soichiro Ishihara, Hiroaki Nozawa, Kazushige Kawai, Keisuke Hata, Tomomichi Kiyomatsu, Toshiaki Tanaka, Takeshi Nishikawa, Kensuke Otani, Koji Yasuda, Koji Murono, Toshiaki Watanabe
BACKGROUND/AIMS: Anastomotic leakage remains the most serious complications of colorectal surgery. To prevent colorectal anastomotic leakage (CAL), an air leak test (ALT) with intraoperative colonoscopy (IOCS) is performed to detect mechanically insufficient colorectal anastomoses. The approaches to an intraoperative anastomotic air leak (IOAL) have not been fully investigated. This study aimed to clarify the safe management of an IOAL in laparoscopic colorectal surgery. METHODS: One hundred forty-eight consecutive patients who underwent laparoscopic resection with double-stapling technique (DST) anastomosis for left-sided colorectal cancer between April 2015 and June 2016 were included and retrospectively reviewed...
September 22, 2017: Digestive Surgery
https://www.readbyqxmd.com/read/28929306/colorectal-anastomotic-leak-delay-in-reintervention-after-false-negative-computed-tomography-scan-is-a-reason-for-concern
#17
C C M Marres, A W H van de Ven, L G J Leijssen, P C M Verbeek, W A Bemelman, C J Buskens
BACKGROUND: Early detection of anastomotic leakage (AL) after colorectal surgery followed by timely reintervention is of crucial importance. The aim of this study was to investigate the accuracy of computed tomography (CT) imaging for AL and the effects of delay in reintervention after a false-negative CT. METHODS: All files from patients who had colorectal surgery with primary anastomoses between 2009 and 2014 were reviewed. The predictive value of CT scanning for AL was determined and correlated with short-term postoperative patient outcomes...
September 2017: Techniques in Coloproctology
https://www.readbyqxmd.com/read/28901001/-early-versus-traditional-postoperative-oral-feeding-in-patients-undergoing-elective-colorectal-surgery-a-meta-analysis-of-safety-and-efficacy
#18
Kun Zhang, Sirong Cheng, Qi Zhu, Zhenguo Han
OBJECTIVE: To compare the outcomes of early oral feeding (EOF) and the traditional oral feeding (TOF) in postoperative patients with colorectal cancer using Meta-analysis. METHODS: The databases of PubMed, SCI, Ovid, The Cochrane Library, CNKI, CBM, VIP and Wanfang Data were searched to collect randomized controlled trial (RCT) about EOF versus TOF in patients undergoing elective colorectal surgery. The retrieval time span was from inception to June 1, 2016. The studies were screened according to the inclusion and exclusion criteria...
September 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28901000/-diagnostic-value-of-dynamic-monitoring-of-c-reactive-protein-in-drain-drainage-to-predict-early-anastomotic-leakage-after-colorectal-cancer-surgery
#19
Jia Lu, Lei Zheng, Runtian Li, Chunmin Hao, Wenbin Gao, Ziwei Feng, Guangya Yin, Yue Wang
OBJECTIVE: To evaluate the diagnostic value of dynamic monitoring of C-reactive protein (CRP) in drainage fluid in predicting early anastomotic leakage after colorectal surgery. METHODS: This study enrolled 172 patients, who were diagnosed as colorectal cancer before operation and underwent radical surgery, without residual tumor tissues by postoperative pathology and perioperative infection, at the Tianjin Medical University Cancer Hospital between July 2015 and January 2016...
September 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28840326/prophylactic-pelvic-drainage-after-rectal-resection-with-extraperitoneal-anastomosis-is-it-worthwhile-a-meta-analysis-of-randomized-controlled-trials
#20
REVIEW
Benjamin Menahem, Antoine Vallois, Arnaud Alves, Jean Lubrano
BACKGROUND: The role of prophylactic pelvic drainage in reducing the postoperative complication rate after rectal surgery remains unclear and controversial. OBJECTIVE: This review and meta-analysis of prospective randomized controlled trials was performed to determine whether drainage of the extraperitoneal anastomosis after rectal surgery impacts the postoperative complication rate. STUDY ELIGIBILITY CRITERIA: Study eligibility criteria included randomized controlled trials comparing prophylactic pelvic drainage after rectal surgery...
November 2017: International Journal of Colorectal Disease
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