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colorectal anastomotic leakage

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https://www.readbyqxmd.com/read/28816967/hand-assisted-laparoscopic-surgery-versus-conventional-open-surgery-in-intraoperative-and-postoperative-outcomes-for-colorectal-cancer-an-updated-systematic-review-and-meta-analysis
#1
Xubing Zhang, Qingbin Wu, Chaoyang Gu, Tao Hu, Liang Bi, Ziqiang Wang
AIM: This meta-analysis aims to compare hand-assisted laparoscopic surgery (HALS) and conventional open surgery (OS) for colorectal cancer (CRC) in terms of intraoperative and postoperative outcomes, and to explore the safety, feasibility of HALS for CRC surgery. METHODS: A systematic literature search with no limits was performed in PubMed, Embase, and Medline. The last search was performed on April 23, 2017. The outcomes of interests included intraoperative outcomes (operative time, blood loss, length of incision, transfusion, and lymph nodes harvested), postoperative outcomes (length of hospital stay, length of postoperative hospital stay, time to first flatus, time to first liquid diet, time to first soft diet, time to first bowel movement, postoperative complications, reoperation, ileus, anastomotic leakage, wound infection, urinary complication, pulmonary infection, and mortality)...
August 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28813634/hand-assisted-laparoscopic-surgery-versus-conventional-laparoscopic-surgery-for-colorectal-cancer-a-systematic-review-and-meta-analysis
#2
Xubing Zhang, Qingbin Wu, Tao Hu, Chaoyang Gu, Liang Bi, Ziqiang Wang
AIM: This meta-analysis aims to compare hand-assisted laparoscopic surgery (HALS) with conventional laparoscopic surgery (LAS) for colorectal cancer (CRC) in terms of intraoperative, postoperative, and survival outcomes. MATERIALS AND METHODS: A systematic literature search with no limits was performed in PubMed, Embase, and Medline. The last search was performed on March 31, 2017. The outcomes of interests included intraoperative outcomes (operative time, blood loss, length of incision, transfusion, conversion, and lymph nodes harvested), postoperative outcomes (length of hospital stay, time to first flatus, time to first bowel movement, postoperative complications, mortality, reoperation, ileus, anastomotic leakage, postoperative bleeding, wound infection, intra-abdominal abscess, urinary complication, cardiopulmonary complication, and readmission), and 5-year survival outcomes...
August 16, 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/28799112/the-dgav-risk-calculator-development-and-validation-of-statistical-models-for-a-web-based-instrument-predicting-complications-of-colorectal-cancer-surgery
#3
Alexander Crispin, Carsten Klinger, Anna Rieger, Brigitte Strahwald, Kai Lehmann, Heinz-Johannes Buhr, Ulrich Mansmann
PURPOSE: The purpose of this study is to provide a web-based calculator predicting complication probabilities of patients undergoing colorectal cancer (CRC) surgery in Germany. METHODS: Analyses were based on records of first-time CRC surgery between 2010 and February 2017, documented in the database of the Study, Documentation, and Quality Center (StuDoQ) of the Deutsche Gesellschaft für Allgemein- und Viszeralchirurgie (DGAV), a registry of CRC surgery in hospitals throughout Germany, covering demography, medical history, tumor features, comorbidity, behavioral risk factors, surgical procedures, and outcomes...
August 10, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28761871/the-usefulness-of-intraoperative-colonic-irrigation-and-primary-anastomosis-in-patients-requiring-a-left-colon-resection
#4
Youngki Hong, Soomin Nam, Jung Gu Kang
PURPOSE: The aim of this study is to assess the short-term outcome of intraoperative colonic irrigation and primary anastomosis and to suggest the usefulness of the procedure when a preoperative mechanical bowel preparation is inappropriate. METHODS: This retrospective study included 38 consecutive patients (19 male patients) who underwent intraoperative colonic irrigation and primary anastomosis for left colon disease between January 2010 and December 2016. The medical records of the patients were reviewed to evaluate the patients' characteristics, operative data, and postoperative short-term outcomes...
June 2017: Annals of Coloproctology
https://www.readbyqxmd.com/read/28746154/anastomotic-leakage-and-chronic-presacral-sinus-formation-after-low-anterior-resection-results-from-a-large-cross-sectional-study
#5
Wernard A A Borstlap, Emma Westerduin, Tjeerd S Aukema, Willem A Bemelman, Pieter J Tanis
OBJECTIVES: Little is known about late detected anastomotic leakage after low anterior resection for rectal cancer, and the proportion of leakages that develops into a chronic presacral sinus. METHODS: In this collaborative snapshot research project, data from registered rectal cancer resections in the Dutch Surgical Colorectal Audit in 2011 were extended with additional treatment and long-term outcome data. Independent predictors for anastomotic leakage were determined using a binary logistic model...
July 25, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28739093/individual-surgeon-is-an-independent-risk-factor-for-leak-after-double-stapled-colorectal-anastomosis-an-institutional-analysis-of-800-patients
#6
Eduardo García-Granero, Francisco Navarro, Carlos Cerdán Santacruz, Matteo Frasson, Alvaro García-Granero, Franco Marinello, Blas Flor-Lorente, Alejandro Espí
BACKGROUND: Our aim was to assess whether the individual surgeon is an independent risk factor for anastomotic leak in double-stapled colorectal anastomosis after left colon and rectal cancer resection. METHODS: This retrospective analysis of a prospectively collected database consists of a consecutive series of 800 patients who underwent an elective left colon and rectal resection with a colorectal, double-stapled anastomosis between 1993 and 2009 in a specialized colorectal unit of a tertiary hospital with 7 participating surgeons...
July 21, 2017: Surgery
https://www.readbyqxmd.com/read/28731950/totally-laparoscopic-resection-for-low-sigmoid-and-rectal-cancer-using-natural-orifice-specimen-extraction-techniques
#7
Hideharu Shimizu, Kensuke Adachi, Hideo Ohtsuka, Itaru Osaka, Kunio Takuma, Kijuro Takanishi, Jun Matsumoto
BACKGROUND: A minilaparotomy for specimen extraction during laparoscopy occasionally results in postoperative wound complications. We have performed a totally laparoscopic resection for early colorectal cancer using the natural orifice specimen extraction technique. METHODS: From 2008 to 2013, we have performed a totally laparoscopic resection for clinical stage I and IIA low sigmoid colon and rectal cancers. A prospectively maintained database was reviewed to assess the outcomes after surgery...
August 2017: Surgical Laparoscopy, Endoscopy & Percutaneous Techniques
https://www.readbyqxmd.com/read/28717916/colon-perfusion-patterns-during-colorectal-resection-using-visible-light-spectroscopy
#8
Henry Hoffmann, Tarik Delko, Philipp Kirchhoff, Rachel Rosenthal, Juliane Schäfer, Marko Kraljević, Christoph Kettelhack
BACKGROUND: The impact of blood supply to the anastomosis on development of anastomotic leakage is still a matter of debate. Considering that bowel perfusion may be affected by manipulation during surgery, perfusion assessment of the anastomosis alone may be of limited value. We propose perfusion assessment at different time points during surgery to explore the dynamics of bowel perfusion during colorectal resection and its impact on outcome. METHODS: In this prospective cohort study, patients undergoing elective colorectal resection were eligible...
July 17, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28687432/nonsteroidal-anti-inflammatory-drugs-and-the-risk-of-anastomotic-leakage-after-anterior-resection-for-rectal-cancer
#9
D Kverneng Hultberg, E Angenete, M-L Lydrup, J Rutegård, P Matthiessen, M Rutegård
BACKGROUND: Nonsteroidal anti-inflammatory drugs (NSAIDs) have been widely used in colorectal surgery due to their opioid-sparing effect. However, several studies have indicated an increased risk of anastomotic leakage following NSAID treatment, although conflicting results exist. The primary goal of this study was to further examine whether postoperative NSAIDs are independently associated with anastomotic leakage after anterior resection for rectal cancer. METHODS: Patients who underwent anterior resection for rectal cancer during 2007-2013 in 15 different hospitals in three healthcare regions in Sweden were included in the study...
June 28, 2017: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28682968/prognostic-impact-of-intra-abdominal-pelvic-inflammation-after-radical-surgery-for-locally-recurrent-rectal-cancer
#10
Masahiro Tanaka, Yukihide Kanemitsu, Dai Shida, Hiroki Ochiai, Shunsuke Tsukamoto, Masato Nagino, Yoshihiro Moriya
BACKGROUND: The influence of postoperative infectious complications, such as anastomotic leakage, on survival has been reported for various cancers, including colorectal cancer. However, it remains unclear whether intra-abdominal/pelvic inflammation after radical surgery for locally recurrent rectal cancer is relevant to its prognosis. OBJECTIVE: The purpose of this study was to evaluate factors associated with survival after radical surgery for locally recurrent rectal cancer...
August 2017: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/28682966/management-of-low-colorectal-anastomotic-leakage-in-the-laparoscopic-era-more-than-a-decade-of-experience
#11
Stephen Alexander Boyce, Craig Harris, Andrew Stevenson, John Lumley, David Clark
BACKGROUND: Anastomotic leak after colorectal surgery increases postoperative mortality, cancer recurrence, permanent stoma formation, and poor bowel function. Anastomosis between the colon and rectum is a particularly high risk. Traditional management mandates laparotomy, disassembly of the anastomosis, and formation of an often-permanent stoma. After laparoscopic colorectal surgery it may be possible to manage anastomotic failure with laparoscopy, thus avoiding laparotomy. OBJECTIVE: The purpose of this study was to determine the feasibility of the laparoscopic management of failed low colorectal anastomoses...
August 2017: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/28664443/vacuum-assisted-early-transanal-closure-of-leaking-low-colorectal-anastomoses-the-clean-study
#12
W A A Borstlap, G D Musters, L P S Stassen, H L van Westreenen, D Hess, S van Dieren, S Festen, E J van der Zaag, P J Tanis, W A Bemelman
INTRODUCTION: Non-healing of anastomotic leakage can be observed in up to 50% after total mesorectal excision for rectal cancer. This study investigates the efficacy of early transanal closure of anastomotic leakage after pre-treatment with the Endosponge(®) therapy. METHODS: In this prospective, multicentre, feasibility study, transanal suturing of the anastomotic defect was performed after vacuum-assisted cleaning of the presacral cavity. Primary outcome was the proportion of patients with a healed anastomosis at 6 months after transanal closure...
June 29, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28634627/influence-of-multiple-stapler-firings-used-for-rectal-division-on-colorectal-anastomotic-leak-rate
#13
Tamara Braunschmid, Nikolaus Hartig, Lukas Baumann, Bernhard Dauser, Friedrich Herbst
BACKGROUND: Anastomotic leakage following colorectal resection remains one of the most significant complications with relevant morbidity and mortality. There is evidence that a higher number of stapler firings for rectal division can affect the leak rate in double stapling anastomosis. However, there are no data concerning compression anastomosis. We present our institutional experience addressing this issue. DESIGN: This is a retrospective review of a prospective institutional database of patients undergoing colonic and rectal resection for benign and malignant indications between January 2008 and December 2014 at the surgical department of the St...
June 20, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28628777/effects-of-adipose-stem-cell-sheets-on-colon-anastomotic-leakage-in-an-experimental-model-proof-of-principle
#14
Panithi Sukho, Geesien S A Boersema, Abigael Cohen, Nicole Kops, Johan F Lange, Jolle Kirpensteijn, Jan Willem Hesselink, Yvonne M Bastiaansen-Jenniskens, Femke Verseijden
The most dreaded complication of colorectal surgery is anastomotic leakage. Adipose tissue-derived stem cell sheets (ASC sheets) prepared from temperature-responsive culture surfaces can be easily transplanted onto tissues. These sheets are proposed to improve cell transplant efficiency and enhance wound healing. The aim of this study was to investigate whether application of ASC sheets could prevent leakage of sutured colorectal anastomoses. Insufficient suturing of colorectal anastomoses was performed in Wistar rats to create a colorectal anastomotic leakage model...
June 9, 2017: Biomaterials
https://www.readbyqxmd.com/read/28628353/effect-of-early-vs-late-start-of-oral-intake-on-anastomotic-leakage-following-elective-lower-intestinal-surgery-a-systematic-review
#15
Boudewijn J J Smeets, Emmeline G Peters, Eelco C J Horsten, Teus J Weijs, Harm J T Rutten, Willem A Buurman, Wouter J de Jonge, Misha D P Luyer
BACKGROUND: Experimental and clinical studies have demonstrated a beneficial effect of early enteral nutrition (EN) on anastomotic leakage following colorectal surgery. Early oral intake is a common form of early EN with various clinical benefits, but the effect on anastomotic leakage is unclear. This systematic review investigates the effect of early vs late start of oral intake on anastomotic leakage following lower intestinal surgery. METHODS: A systematic literature search was performed using the PubMed, Embase, Medline, and Cochrane databases...
June 1, 2017: Nutrition in Clinical Practice
https://www.readbyqxmd.com/read/28614172/the-relationship-between-the-number-of-intersections-of-staple-lines-and-anastomotic-leakage-after-the-use-of-a-double-stapling-technique-in-laparoscopic-colorectal-surgery
#16
SeungHun Lee, ByungKwon Ahn, SeungHyun Lee
PURPOSE: Laparoscopic intracorporeal colorectal anastomosis with double stapling technique is difficult because of unsuitable cutting angle in narrow pelvic cavity. For reasons of tilted and long linear staple line of rectal stump, circular anastomotic plane can make multiple intersections. The present study was designed to assess whether multiple intersections after double stapling technique is the risk factor of anastomotic complication in laparoscopic colorectal surgery. MATERIALS AND METHODS: In total, 128 consecutive left colon and rectal cancer patients who underwent laparoscopic rectal resection with double stapling technique were enrolled in this study...
August 2017: Surgical Laparoscopy, Endoscopy & Percutaneous Techniques
https://www.readbyqxmd.com/read/28612478/high-stoma-prevalence-and-stoma-reversal-complications-following-anterior-resection-for-rectal-cancer-a-population-based-multi-centre-study
#17
Klas Holmgren, Daniel Kverneng Hultberg, Markku M Haapamäki, Peter Matthiessen, Jörgen Rutegård, Martin Rutegård
AIM: Fashioning a defunctioning stoma is common when performing an anterior resection for rectal cancer in order to avoid and mitigate consequences of an anastomotic leakage. We investigated the permanent stoma prevalence, factors influencing stoma outcome and complication rates following stoma reversal surgery. METHODS: Patients who had undergone an anterior resection for rectal cancer between 2007 and 2013 in the Northern healthcare region were identified using the Swedish Colorectal Cancer Registry and were followed until the end of 2014 regarding stoma outcome...
June 14, 2017: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/28608118/oncologic-impact-of-anastomotic-leakage-following-colorectal-cancer-surgery-a-systematic-review-and-meta-analysis
#18
Gi Won Ha, Jong Hun Kim, Min Ro Lee
BACKGROUND: Anastomotic leakage (AL) is a major complication of surgery for colorectal cancer (CRC), and is associated with increased morbidity and mortality; However, there are conflicting results on the impact of AL on long-term oncologic outcomes. OBJECTIVE: The aim of this meta-analysis was to assess the oncologic outcomes of AL following restorative surgery for CRC. METHODS: Multiple comprehensive databases, including PubMed, EMBASE, and The Cochrane Library, were searched for studies that assessed the oncologic effects of AL following surgery for CRC...
June 12, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/28595813/reinforcement-of-the-colon-anastomosis-with-cyanoacrylate-glue-a-porcine-model
#19
Geesien S A Boersema, Sandra Vennix, Zhouqiao Wu, Maaike Te Lintel Hekkert, Dirk-Jan G M Duncker, King H Lam, Anand G Menon, Gert-Jan Kleinrensink, Johan F Lange
BACKGROUND: Previous experimental studies on cyanoacrylate (CA) glue for the prevention of colorectal anastomotic leakage (AL) have shown promising results. The aim of this study was to investigate the effect of CA in prevention of leakage in a porcine model of ischemic colorectal AL. METHODS: Twenty-four animals were divided into four groups of six: (1)ischemic anastomosis with sufficient suture (ISCH), (2)ischemic anastomosis with sufficient suture and CA reinforcement (CA-ISCH), (3)ischemic anastomosis with insufficient suture (ISCH-AI), and (4)ischemic anastomosis with insufficient suture and CA reinforcement (CA-ISCH-AI)...
May 10, 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28594720/clinical-relevance-of-a-grading-system-for-anastomotic-leakage-after-low-anterior-resection-analysis-from-a-national-cohort-database
#20
Martine A Frouws, Heleen S Snijders, Steve H Malm, Gerrit-Jan Liefers, Cornelis J H Van de Velde, Peter A Neijenhuis, Hidde M Kroon
BACKGROUND: Anastomotic leakage is a severe complication after low anterior resection for rectal cancer. With a global increase in registration initiatives, adapting uniform definitions and grading systems is highly relevant. OBJECTIVE: This study aimed to provide clinical parameters to categorize anastomotic leakage into subcategories according to the International Study Group of Rectal Cancer. DESIGN: All of the patients who underwent a low anterior resection in the Netherlands with primary anastomosis were included using the population-based Dutch Surgical Colorectal Audit...
July 2017: Diseases of the Colon and Rectum
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